{"text": "Between 2% and 5% of malignant germ-cell tumors in men arise at extragonadal sites. Of extragonadal germ cell tumors, testicular carcinoma in situ (CIS) are present in 31\u201342% of cases, and CIS are reported to have low sensitivity to chemotherapy in spite of the various morphology and to have a high likelihood of developing into testicular tumors. A testicular biopsy may thus be highly advisable when evaluating an extragonadal germ cell tumor.A 36-year-old man was diagnosed as having an extragonadal non-seminomatous germ cell tumor, that was treated by cisplatin-based chemotherapy, leading to a complete remission. In the meantime, testicular tumors were not detected by means of ultrasonography. About 4 years later, a right testicular tumor was found, and orchiectomy was carried out. Microscopically, the tumor was composed of seminoma.We herein report a case of metachronous occurrence of an extragonadal and gonadal germ cell tumor. In the evaluation of an extragonadal germ cell tumor, a histological examination should be included since ultrasonography is not sufficient to detect CIS or minute lesions of the testis. Between 2% and 5% of malignant germ-cell tumors in men arise at extragonadal sites . Cytogenrd July. Pathology showed the resected tumor was a seminoma with CIS .2. The side effect of CIS therapy  are significant, especially concerning fertility and androgen production.3. Testicular tumors early detected by adequate surveillance respond well to treatments.4. Testicular biopsy is not entitled to detect all the CIS.The author(s) declare that they have no competing interests.IK, MU, HY, KN, TT and ND carried out clinical treatments.TM carried out histopathological studies.The pre-publication history for this paper can be accessed here:"}
{"text": "Late relapses of testicular germ cell tumor are uncommon. We report a case of cervical mature teratoma appeared 17 years after treatment of testicular teratocarcinoma.A 20- year- old patient underwent left sided orchiectomy followed by systemic therapy and retroperitoneal residual mass resection in 1989. He remained in complete remission for 200 months. In 2005 a huge left supraclavicular neck mass with extension to anterior mediastinum appeared. Radical surgical resection of the mass was performed and pathologic examination revealed mature teratoma.This is one of the longest long-term reported intervals of a mature teratoma after treatment of a testicular nonseminoma germ cell tumor. This case emphasizes the necessity for follow up of testicular cancer throughout the patient's life. The prognosis for nonseminomatous germ cell tumor (NSGCT) of the testis has been dramatically improved by using a treatment protocol of cisplatin-based chemotherapy followed by surgical resection of residual tumor mass. The complete response rate of disseminated germ cell tumor with this protocol is between 70%\u201380%.Most patients who relapse do so within the first year of therapy. Late relapse is defined as recurrence after a relapse- free interval of more than two years after completion of primary treatment . The cumThe incidence of late relapse after cisplatin based chemotherapy of germ cell tumor is related to initial tumor burden and patients with bulky retroperitoneal disease appear to be at an increased risk of late relapse. As tumor markers do not rise in one quarter of late relapses, they should undergo CT scans at annual follow-up evaluations. In the remaining patients, history, physical examination, tumor markers and chest X-ray may allow to detect the majority of late asymptomatic relapses .Herein we report a case of late relapse of a bulky teratocarcinoma, 17 years after completion of treatment as a mature teratoma of the neck and upper thorax.A 36 year-old man was admitted to our hospital with chief complaint of left sided neck mass. He had a history of left orchiectomy in 1988 in another center because of testicular teratocarcinoma. At that time he was referred to our center because of huge retroperitoneal mass medial to the left kidney Figure . The othGerm cell tumours, which are in complete remission two years after treatments have a high probability of cure and reports of late relapse, are rare 1.3%\u20136.2%) [% [2-6]. The possible mechanisms of development of a late relapse in germ cell tumors include the followings: malignant degeneration of mature teratoma to germinal malignancy, growth of an occult testicular tumor not eliminated by chemotherapy, development of a second primary germinal malignancy, persistent microscopic viable tumor with an atypical less aggressive biologic behaviour .Patient with bulky retroperitoneal disease and patient found to have teratoma following cisplatin-based chemotherapy appear to be at an increased risk of late relapse. Of 51 patients with mature teratoma in resected retroperitoneal residual tumor masses after chemotherapy, 9 patients (17.6%) relapsed. In five patients (9.8 %) relapse resulted from growing mature teratoma [Teratoma is a chemo resistant, nonseminomatous germ cell tumor composed of somatic cell type from two or more germ layers and is derived from a toti potential, malignant precursor cell . Although teratoma is a benign tumor but its biologic potential is unpredictable and it should be resected completely because it may grow and become unresectable.Disease free survival following resection of teratoma is related to completeness of resection; therefore, there are significant advantages to surgery with low volume disease. Moreover, there is the risk of malignant transformation of teratoma to carcinoma or sarcoma , so unreHerein we report a case of late relapse in the left side of neck 17 years after treatment of left testicular teratocarcinoma. The incidence of cervical metastasis in testicular germ cell tumor is about 5% . In germWhereas chemotherapy has only minor curative potential in the treatment of late relapse, patient with localized resectable disease can be cured. Modified neck dissection has a demonstrated valuable role in the treatment of metastatic non-seminomatus germ cell tumours .Our patient has been well with no evidence of disease after resection of cervical mature teratoma until the date of last follow-up (October 2006). However, continued close follow-up of this case is necessary because the large tumor burden of teratoma is a significant adverse factor predictive for further relapse . In our This case emphasizes the necessity of annual follow-up evaluation of testicular germ cell cancer patient through their life, in order to detect the majority of late relapse at an asymptomatic phase.The author(s) declare that they have no competing interest.RO carried out the surgery and drafted the manuscript.MA assisted in operation and participated in drafting the manuscript.All authors read and approved the final manuscript."}
{"text": "Clear cell sarcoma of the kidney (CCSK) in adults is extremely rare. Optimal treatment of adult patients with CCSK remains unclear.A 22-year-old man presented with a 2-month history of left flank pain. A color duplex sonography revealed a hypervascular, heterogeneous renal mass. Abdominal and pelvic computerized tomography showed a heterogeneous mass originating from the lower pole of the left kidney and infiltrating to the psoas muscle. Further evaluation including bone scan did not demonstrate any evidence of metastases. A left radical nephrectomy with hilar lymphadenectomy through an intraperitoneal approach with an anterior subcostal incision was performed. The histopathological diagnosis of the mass was a clear cell sarcoma of the kidney. No lymph node metastases were found. Concomitant chemo-radiotherapy was performed. Therapy-related serious side effects were not observed. There was no evidence of local recurrence or metastases during the following twenty-four months after therapy.We believe that the combination therapy is efficacious for preventing the local recurrence and distant metastases. Accurate diagnosis is very important and therapy must also include doxorubicin regardless of the disease stage in adult patients with CCSK. Clear cell sarcoma of the kidney (CCSK) is an uncommon pediatric neoplasm distinct from Wilms tumor and also usually tends to metastasize to bones being different from Wilms tumor .CCSK in adults is extremely rare. Optimal treatment of adult patients with CCSK remains unclear. Surgery, radiotherapy and chemotherapy are combined or used separately -4. AdvanHerein, we report a 22-year-old patient with clear cell sarcoma of the left kidney, who was managed with radical nephrectomy, radiotherapy and chemotherapy. We think that our case report might provide additional information about the treatment of CCSK in adults.A 22-year-old man presented with a 2-month history of left flank pain. A color duplex sonography revealed a hypervascular, heterogeneous renal mass 125 \u00d7 156 \u00d7 195 mm. in diameter. Abdominal and pelvic computerized tomography showed a heterogeneous mass originating from the lower pole of the left kidney and infiltrating to the psoas muscle  declare that they have no competing interests.Dr.s ARK and BO have provided the patients and performed the radical nephrectomy, HO has reviewed the charts, CC has evaluated the pathology specimen, IA and FYA have performed the concomitant chemo-radiotherapy. All authors read and approved the final manuscript.The pre-publication history for this paper can be accessed here:"}
{"text": "We report herein a rare case of primary omental gastrointestinal stromal tumor (GIST).\u00ae and is alive well with no sign of relapse.A 65 year-old man was referred to our hospital with a huge abdominal mass occupying the entire left upper abdomen as shown by sonography. On computed tomography (CT), this appeared as a heterogeneous low-density mass with faint enhancement. Abdominal angiography revealed that the right gastroepiploic artery supplied the tumor. With such an indication of gastric GIST, liposarcoma, leiomyosarcoma or mesothelioma laparotomy was performed and revealed that this large mass measured 20 \u00d7 17 \u00d7 6 cm, arising from the greater omentum. It was completely resected. Histopathologically, it was composed of proliferating spindle and epithelioid cells with an interlacing bundle pattern. Immunohistochemically, the tumor was positive for myeloid stem cell antigen (CD34), weakly positive for c-KIT (CD117) and slightly positive for neuron-specific enolase (NSE), but negative for cytokeratin (CK), alpha-smooth muscle actin (SMA) and S-100 protein. A mutation was identified in the platelet-derived growth factor alpha (PDGFRA) juxtamembrane domain  and the tumor was diagnosed as an omental GIST. The postoperative course was uneventful. The patient is treated by Glevec561 substitution. Imatinib therapy as an adjuvant to complete resection has been carried out safely. Because of the rarity of primary omental GISTs, it is inevitable to analyze accumulating data from case reports for a better and more detailed understanding of primary omental GISTs.Our case demonstrated a weak immunohistochemical expression of c-kit (CD117) and a point mutation in PDGFRA exon 12 resulting in an Asp for Val GISTs are mesenchymal tumors, the majority of which is KIT CD117)-positive, typically arising in association with the muscularis propria of the gastrointestinal tract wall. Accordingly, they occur most frequently in the stomach (60%), jejunum and ileum (30%), and less frequently in the duodenum (5%), < 5% colorectal < 1% in the esophagus and appendix 17-positi. To the Here, we report a rare case of primary omental myxoid epithelioid GIST which we have characterized immunohistochemically and genetically. We review the English-language literature on primary omental GISTs.\u00ae 300 mg/day as an adjuvant postoperative molecular targeting chemotherapy and has been living disease-free for 6 months.A 65-year-old man was referred to our hospital in October 2006 with a huge abdominal tumor. A firm mass was palpated extending from the epigastrium to the left hypogastrium. There were no laboratory abnormalities, except a slight elevation of the total bilirubin 1.3 mg/dl) and lactate dehydrogenase (LDH: 217 IU/L) levels in the serum. The tumor markers carcinoembryonic antigen (CEA) and carbohydrate antigen (CA19-9) were within the normal range. Ultrasonography showed that the mass occupied almost the entire upper abdomen anterior to the bowel loops. On computed tomography (CT), a mass behind the left hepatic lobe showed heterogeneous low density with faint enhancement  [Because of possible relapse even after complete resection of omental GISTs -16 and tmerican) ,16. At t561 substitution. Because of the rarity of primary omental GISTs, it is difficult to assess their malignant potential and their overall prognosis. Imatinib therapy as an adjuvant to complete resection has been carried out safely and may prevent relapse to prolong long-term survival. It is essential to analyze accumulating data from case reports for a better and more detailed understanding of primary omental GISTs.Our case demonstrated a weak immunohistochemical expression of c-kit (CD117) and a point mutation in PDGFRA exon 12 resulting in an Asp for ValThe author(s) declare that they have no competing interests.TS, SS and AS had contributed as molecular tumor pathologist. TS, KF, SY, RM and TM contributed as a gastrointestinal surgeon in operative performance and postoperative treatment. NH and YT contributed as gastroenterologist and diagnostic radiologist.All authors read and approved the final manuscript."}
{"text": "Late relapse of a testicular germ cell tumour is an uncommon occurrence. We report a case of osteolytic bone metastasis appearing 23 years after the initial treatment of a metastatic testicular mixed tumour . This is one of the longest periods of recurrence reported for testicular germ cell tumours.A 52-year-old Caucasian man who underwent a right inguinal orchiectomy due to testicular tumour in 1984 presented to our outpatient clinic in a generally bad condition of health and with severe pain of his right hip joint and os ischii caused by osteolytic metastasis.This case emphasizes the need for a life-long follow-up of patients with primary metastatic testicular cancer. The prognosis of malignant testicular tumour has dramatically improved due to cisplatin-based chemotherapy. When diagnosed at an early stage, the disease has a cure rate of 95% to 100%. In advanced stages, cure rates of up to 70% are still possible . HoweverThe most complete report of late relapse was published by Baniel et al. . The autWe report here a case of a late relapse of a germ cell tumour, which occurred 23 years after orchiectomy and following four cycles of chemotherapy and five years of complete remission.A 52-year-old man presented to our outpatient clinic in a bad general condition of health and with severe pain of his right hip joint and os oschii. The pain developed approximately three months prior to presentation.The patient's medical history revealed a right inguinal orchiectomy for the removal of testicular tumour performed in France in 1984. The rest of his anamnesis was clinically insignificant.In 1984, the patient's histopathology revealed a mixed tumour, a choriocarcinoma and an embryonic carcinoma, with retroperitoneal and pulmonary metastases. To treat this, an orchiectomy was performed, followed by four cycles of bleomycin, etoposide and cisplatin (BEP) chemotherapy. Follow-up assessments were initially performed at an interval of three months, and then at an interval of six months until the fifth postoperative year.When the patient presented to our clinic, he appeared to be in bad general health, with severe pain in his right hip joint. His serum level of alpha-fetoprotein was 169.48 ng/ml  and beta-human chorionic gonadotropin (\u00df-hCG) was 1.30 mIU/ml . The patient's lactate dehydrogenase (LDH) level was 1155 U/L  and his alkaline phosphatase level was 104 U/L .Radiological investigation, which was later confirmed through computer tomograms, demonstrated that there was an osteolytic destruction of the patient's os ischii and hip joint Figure . In addiA biopsy of the lytic bone lesion was carried out to confirm the diagnosis. Histological and immunohistochemical investigation of the biopsy cylinders showed an anaplastic seminoma Figure . ImmunohDue to strong pain, analgesia with peripheral and central analgesics was initiated. During the next three days, however, the state of our patient dramatically declined and he died a day before the results of the biopsy were known.After initial therapy, patients with germ cell tumours who have two years of complete remission have a high cure rate. The probability of a late relapse is between 1.3% and 7% -6]. L. L6]. LaLate relapse is defined as a germ cell tumour that appears more than two years after therapy and complete remission . Of the A series of 1263 patients with germ cell testicular tumour treated at the Department of Radiotherapy and Oncology in Surrey, United Kingdom showed that only 14 patients had late relapse between the 5th and 10th year after primary treatment with a calculated annual risk of 1%. In two patients, late relapse occurred later than 10 years. One of these patients presented with metastatic seminoma, while the other presented with nonseminoma during the clinical stage I, which was then followed up by a wait-and-see attitude .The possible mechanisms for the development of late relapses are identified as: 1) the presence of mature teratoma in the germ cell tumour; 2) the growth of the remaining tumour not destroyed by the chemotherapy; and 3) the development of a secondary germ cell carcinoma and the microscopic persistence of tumour cells with atypical biological behaviour .Albers et al. wrote the European Association of Urology (EAU) guidelines on testicular cancer in a limited update in March 2009. Precise recommendations for minimum follow-up schedules in advanced nonseminomatous germ cell tumours and seminoma were provided, indicating the procedures that should be performed at one, two and three to five years after initial therapy and thereafter [Late relapses respond weakly to chemotherapy. Surgical excision remains the best treatment. Baniel et al. showed that chemotherapy alone yields poor results in patients with late relapse . Tumour-Late relapse of malignant germ cell tumours are a rare occurrence. Until recently, it was generally considered sufficient to perform follow-up assessments for up to five years after initial therapy. However, metastatic nonseminomatous tumours form an exception to this general rule, and late tumour relapses do occur. It thus seems necessary that follow-up examinations be performed for longer than five years after the primary therapy. This regime is recommended in the latest 2009 update of the EAU guidelines on testicular cancer as written by Albers and his co-authors.AFP: alpha-fetoprotein; BEP: bleomycin, etoposide and cisplatin; CEA: carcinoembryonic antigen; EAU: European Association of Urology; hCG: Human chorionic gonadotropin; LDH: lactate dehydrogenase.We were unable to obtain consent for the publication of this case due to the death of the patient and despite repeated attempts we were unable to trace the next of kin. Every effort has been made to keep the patient's identity anonymous. We would not expect the patient's family to object to publication.The authors declare that they have no competing interests.GS and TG performed the bone biopsy. SE performed the histological examination. BA was a major contributor in writing the manuscript. All authors read and approved the final manuscript."}
{"text": "Testicular cancer is the most common cancer for males aged 15~35 years old. The initial presentation is typically an asymptomatic enlarged testicle. The retroperitoneum is the most common metastatic area. Other metastatic sites include the lung, liver, brain, adrenal glands, gastrointestinal tract and spleen. Skin metastasis is a rare event and frequently associated with poor prognosis.A 19-year old male was diagnosed testicular mixed germ cell tumor with initial presentation of cutaneous metastasis at scalp and upper abdomen. After radical orchiectomy and four courses of cisplatin-based chemotherapy, the scalp and upper abdominal lesions regressed completely. The size of lung metastases remained unchanged.For advanced stage testicular cancer, cisplatin-based chemotherapy is still effective to achieve partial response. Cutaneous manifestation of an internal malignancy is rare, with an incidence of 2.9-9%,2. The fA 19-year-old male was in good health conditions before admission. He suffered progressively enlarging upper abdominal skin lesions and scalp nodules for 3 months fig. . These nCutaneous metastases originating from a solid organ are roughly 2% . Most ofTesticular mixed germ cell tumors are common, comprising roughly 33% of all testicular tumors. The reason for such a high incidence of testicular mixed germ-cell tumors is because germ cells in the testes are totipotent and can undergo either trophoblast or somatic differentiation. Among all the subtypes of testicular germ cell tumor, choriocarcinoma is the most aggressive with highly metastatic potential .The cutaneous metastasis as the first sign of metastatic choriocarcinoma could have been either an occult or a slow growing primary testis germ cell tumor -15. CutaAccording to the International Germ Cell Consensus Prognosis for Testicular Cancer, the 5-yThe skin is an uncommon site for testicular germ cell metastasis. A cutaneous lesion can be difficult to be differentiated from a primary cutaneous neoplasm. Excisional biopsy is required for definite diagnosis. For advanced stage testicular cancer, cisplatin-based chemotherapy is still effective to achieve biochemical remission.The authors declare that they have no competing interests with people or organizations in preparation of this study.Written informed consent was obtained from the patient for publication of this case report and accompanying images. A copy of the written consent is available for review by the Editor-in-Chief of this journal.KLC was the first author, responsible for the conception and design for the manuscript, the clinical work, the search for the literature, and the editing work.SHU was responsible for the histopathological work. STP, HCC, YHC and CCL helped in the clinical work as well as the literature review. STP and SKL were responsible for editorship of the manuscript. CKC is the head of the department who supervised all the steps of the work."}
{"text": "A burned-out seminoma of the testis is an exceptionally rare clinical entity, with few reports found in the literature.A case of burned-out tumor of the testis in a 31-year-old man is reported. The tumor presented as a retroperitoneal mass with histological characteristic of a seminoma. The testes on clinical examination were normal, and a suspicious lesion in the scrotum was only identified after ultrasound. Incision of the abdominal mass was decided, followed by orchectomy. Histological examination of the testis revealed a suspicious lesion with characteristics of spontaneous regression of germ cell tumors.We describe one of very few cases worldwide, where spontaneous regression of a primary testicular tumor occurred after demonstration of retroperitoneal lymph node metastasis, a phenomenon known as burned-out seminoma, which is hard to recognize and incompletely characterized by physicians. Seminoma is the most frequent carcinoma of the testicle in the fourth decade of life and constitutes 60% to 65% of germ cell neoplasias. Several histopathologic characteristics of the tumor have been evaluated and three types of pure seminoma have been described as follows: a) classic, b) anaplastic and c) spermatocytic.Internationally, three clinical stages for the determination of the extension of the tumor are admissible. Stage I is where the tumor is limited to the testis with or without invasion of epididymis or the spermatic cord. In Stage II the tumor has retroperitoneal lymph node metastases. Finally, in Stage III the tumor has distant metastases.The germ cell tumor often gives lymph node metastasis, except from choriocarcinoma, which in an aggressive fashion is characterized by early hematogenous spread. We describe one of the very few cases worldwide where the spontaneous regression of a primary testicular tumor occurred after demonstration of retroperitoneal lymph node metastasis, a phenomenon known as burned-out seminoma.A 31-year-old man presented with symptoms of incomplete ileus . The patient had no relevant past medical history. Abdominal CT scan showed a retroperitoneal mass of 7 \u00d7 7 \u00d7 5 cm extending along the left side of the aorta, compressing but not completely occluding the left renal vein (Figure The patient had extensive resection of the retroperitoneal mass and lymphadenectomy. Histological examination showed a mass with a thin peripheral necrotic zone and associated dystrophic calcifications and persistent fibrous and inflammatory areas. The neoplastic cells had lymphoplasmacytic and eosinophilic infiltration, which varied in intensity, and numerous nuclear mitotic actions Figure . ImmunohHistological examination of the testis after radical left orchidectomy showed a well-demarcated nodular scar. Many tubules had a Sertoli cell only pattern and others were completely hyalinized. Increased vascularity was manifested by a collection of small, atrophic, non-arborizing vessels. Testicular atrophy was demonstrated by shrunken tubules with decreased or absent spermatogenesis and thickened peritubular basement membranes peripheral to the scar Figures  and 5. TThe phenomenon of spontaneous regression of cancer has not been fully elucidated; it may possibly be defined as partial or complete disappearance of the tumor with no therapy and has been described in renal tumours, breast carcinoma, lymphoma and malignant melanoma .Burned-out seminoma is the spontaneous regression of a testicular germ cell tumor with or without metastasis. In our case report, the primary testicular tumor with histological characteristics of a seminoma regressed after the development of metastasis in the retroperitoneum. Several immunological and ischemic mechanisms have been suggested to explain this spontaneous regression , but immIn patients who present with a retroperitoneal mass, diagnosis of metastatic progression of a germ cell neoplasia should be considered. A burned-out testicular tumor shows a distinctive constellation of findings that usually permits its recognition, which is significant because pure seminomatous germ cell tumors have a long term chance of cure, irrespective of the primary tumor site.CT: computed tomography; \u03b1-FP: \u03b1-fetoprotein; \u03b2-hCG: \u03b2 human chorionic gonadotrophin; LDH: lactate dehydrogenase; PLAP: placental alkaline phosphatase; SUS: scrotal ultrasonography.Written informed consent was obtained from the patient for publication of this case report and accompanying images. A copy of the written consent is available for review by the Editor-in Chief of this journal.The authors declare that they have no competing interests.All authors contributed to conceptualizing and writing this case report."}
{"text": "Germ-cell tumors are a high-proliferative type of cancer that may evolve to significant bulky disease. Tumor lysis syndrome is rarely reported in this setting. The reports of three patients with germ-cell tumors who developed severe acute tumor lysis syndrome following the start of their anticancer therapy are presented. All patients developed renal dysfunction and multiorgan failure. Patients with extensive germ-cell tumors should be kept on close clinical and laboratory monitoring. Physicians should be aware of this uncommon but severe complication and consider early admission to the intensive care unit for the institution of measures to prevent acute renal failure. Acute tumor lysis syndrome (ATLS) is a clinical condition that results from the massive destruction and lysis of malignant cells, and subsequent release of intracellular ions and metabolites into the bloodstream leading to hyperkalemia, hyperphosphatemia, hyperuricemia, and hypocalcemia. ATLS is accompanied by renal failure and metabolic acidosis thus increasing the risk of death. The syndrome is usually a consequence of the treatment of high-grade lymphoproliferative malignancies. It is rarely observed in patients with solid tumors and even less frequent is its spontaneous presentation.\u20133 Germ-cA 41-year-old male presented with left testicular mass, weight loss, dry cough followed by hemoptysis and progressive dyspnea. Computed tomography (CT) scans showed a large retroperitoneal mass and metastases to the lungs, liver, and spleen. There were high levels of human chorionic gonadotropin (HCG) (317.718 mU/ml) and of \u03b1-fetoprotein (93 ng/ml). The patient underwent a radical left orchiectomy and the hystopathological examination showed a mixed germ-cell tumor . On the first day of chemotherapy with bleomycin, etoposide, and cisplatin, he developed massive hemoptisys, acute respiratory failure, and cardiopulmonary arrest. Cardiopulmonary resuscitation was successfully performed. On day 2, he evolved with metabolic acidosis, hyperphosphatemia (8.8 mg/dl), hyperuricemia (9.4 mg/dl), hypocalcemia (6.1 mg/dl), and hyperkalemia (6.7 mEq/l). Chemotherapy was interrupted and hemodyalisis was started. However, the patient died on day 7 due to multiple organ failure.A 39-year-old male presented with weight loss, progressive dyspnea, and right testicular enlargement. CT scan showed large mediastinal, intraperitoneal, and retroperitoneal masses , 2. SeruA 30-year-old male presented with back pain, bilateral leg edema, and dyspnea because of a large retroperitoneal mass and multiple pulmonary nodules. Ultrasound examination disclosed hydronephrosis of the right kidney and deep vein thrombosis. There was no palpable testicular mass on physical examination, but a right testicular nodule was disclosed by ultrasound examination. Tumor markers showed a serum \u03b1-fetoprotein of 19.078 U/l, HCG of 5.4 U/l, and LDH of 7.150 U/l. The patient underwent right radical orchiectomy and nonseminomatous tumor was diagnosed. Etoposide and carboplatin were started. However, on day 1 of chemotherapy, he developed acute respiratory failure requiring mechanical ventilation and was transferred to the ICU. Vigorous hydration and alopurinol were started concerning the risk of tumor lysis syndrome. Nonetheless, the patient developed low urine output, metabolic acidosis, azotemia, hyperphosphatemia, hyperuricemia, hyperkalemia, and hemodynamic instability. Chemotherapy was stopped and broad-spectrum antibiotics and hemodyalisis were started. On day 6, he presented with progressive pancytopenia requiring the use of filgrastim. The patient evolved with progressive improvement of his clinical condition, mechanical ventilation was discontinued on day 22, and he was discharged to the wards on day 24. In the wards, his renal function improved allowing to the discontinuation of hemodyalisis. The patient went home on day 42 with normal renal function and lower tumor markers levels . He received three additional courses of bleomycin, etoposide, and carboplatin with no serious side effects. Two months later, he underwent an exploratory laparotomy and there was no evidence of retroperitoneal masses. However, there was disease progression characterized by the development of recurrent metastases in the central nervous system refractory to surgery, chemotherapy, and radiation therapy. The patient died 20 months after index hospital admission.The reports of three patients with extensive disseminated germ-cell tumors who developed severe ATLS following the start of chemotherapy were presented. ATLS has been occasionally described in patients with solid tumors such as melanoma, medulloblastoma, small-cell lung cancer, neuroblastoma, and germ-cell tumors.\u20135 The ob"}
{"text": "A huge retroperitoneal tumor with a right orbital mass was detected and proved to be an extragonadal nonseminomatous germ cell tumor on biopsy. BEP chemotherapy caused some regression in orbital mass however no change in retroperitoneal tumor size as well as serum tumor marker levels occurred. Herein, we present a rarely seen entity of extragonadal retroperitoneal nonseminomatous germ cell tumor with synchronous orbital metastases and discuss its diagnosis and management. Extragonadal germ cell tumors (EGGCT) accountfor approximately 2\u20135% of all germcell tumors. They are mostly seen in the mediastinum and retroperitoneum. However,it can also be seen in less frequent locations such as sacrococygeal region,pineal region, prostate, orbita, liver, vagina, and gastrointestinal tract , 2.These lesions may grow up to extensivedimensions without any significant symptoms. The diagnosis is usually made in thethird decade. Advanced local disease and distant metastases might exist at thetime of diagnosis in the majority of patients .\u03b2 HCG) level (37.8 mIU/mL) and an increased lactate dehydrogenase (LDH)level (800 IU/L). Serum alpha fetoprotein (AFP) level was within normal limits.A 31-year-old man complaining of bilaterallumber pain, fatigue was diagnosed with right hydronephrosis on ultrasonography (US), and a double J stent was placed into the right ureter at another hospital amonth ago. He then was referred to our institution for further evaluation. Hispast medical history revealed bilateral nephrolithotomy in 1998 and rightnephrolithotomy in 1999. Physical examination of urogenital system was withinnormal limits including the scrotal examination. On admission, there was proptosis(eccentric) present displacing his right eye infero-nasally. His blood hemoglobulinand leukocyte counts were 7.81 g/dL and 21 500, respectively. Blood chemistrywas within normal limits except elevated urea (49 mg/dL) and creatinine (2.1 mg/dL) levels. Serum tumor marker studies revealed an increased beta-humanchorionic gonadotropin  germ cell tumor (EGGCT) with orbital metastasis. Chemotherapy including cisplatin, etoposide, and bleomycine (BEP) wasadministered. After completion of first course chemotherapy, symptoms subsidedwith a significant reduction in proptosis. However, serum tumor marker levelsdid not change. Afterwards, a very rapid progression of the disease has occurredfollowing initial regression of his symptoms. Dimensions of orbital lesion increasedsignificantly with concomitant increase in serum tumor marker levels including AFPand EGGCTs are rarely seen tumors with specificbiological and clinical characteristics. Symptoms depend on the location of thetumor such as presence of a palpable mass, abdominal or back pain, dysphagia, andedema in the limbs when the tumor is located in the retroperitoneum. Constitutionalsymptoms such as fever and weight loss might accompany the disease. Thediagnosis is made histopathologically when seminomatous and nonseminomatouselements of the tumor are seen on biopsy. Tumor markers are also expected toincrease if nonseminomatous elements are present , 2.In our patient, main symptoms were abdominaland low back pain. Immunohistochemical evaluation of the biopsy for AFP and HCGstaining were positive therefore, the patient was diagnosed as having extragonadalnonseminomatous germ cell tumor.Metastases to other tissues depend on thelocalization and histological type of the primary tumor . Lung meScrotal US could easily differentiate aretroperitoneal EGGCT from primary testicular tumor metastases without routinelyperforming testicular biopsy for differential diagnosis .The prognosis is excellent in cases withseminomatous histology regardless of the localization of the EGGCT either in mediastinumor in retroperitoneum. However, prognosis of nonseminomatous EGGCT is worsethan that of the seminomatous variant. Five-year-survival rates have beenreported to be 45% for mediastinal and 62% for retroperitoneal nonseminomatoustumors [Management of patients with EGGCT is accomplishedaccording to the prognostic classification of International Germ Cell Cancer Collaboration Group . StandarSecondary surgery is an integral part of thetreatment strategy in patients with EGGCT and is mandatory in cases withresidual mass, which is true for about 50% of the patient population .We intended to treat our patient with 4 coursesof BEP chemotherapy; however, we were able to administer only two courses. Unfortunately,we lost the patient despite partial response with some regression in thediameter of the orbital mass without any change in serum tumor marker levels.In our case, a right orbital mass accompanyingthe retroperitoneal tumor which we think was metastasis rather than anotherprimary focus regressed after the administration of first course of BEPchemotherapy. Because the volume of the orbital tumor mass was smaller than thevolume of the retroperitoneal tumor, we think that orbital tumor regressed tosome degree while the retroperitoneal mass remained unchanged without anychange in serum tumor marker levels."}
{"text": "We report a case of primary mediastinal seminoma, which presented initially with shortness of breath and a swelling in upper part of anterior chest wall. The diagnosis of primary mediastinal seminoma was established on the basis of histologic findings and was confirmed by immunohistochemical analysis. Abdominal, pelvis and cerebral CT scan, testicular ultrasound and TC-99 MDP bone scintigraphy were negative. Chemotherapy was initiated with B.E.P. protocol ; the patient received four cycles of chemotherapy. After 8 months, the patient was seen in the clinic; he was well. Primary seminomas of the mediastinum are unusual neoplasms that are morphologically indistinguishable from their gonadal counterparts but may have different biologic behavior because they arise at this particular location. The anterior mediastinum is the most common primary extragonadal site for seminoma. There are very few published reports of mediastinal seminomas located in middle and posterior mediastinum.The case presented in this report highlights the importance of considering primary mediastinal seminoma in the differential diagnosis of anterior, middle and posterior mediastinal mass even if no abnormality of the testicle is observed.A 32-year-old male patient was admitted to the hospital with a 6-month history of retrosternal chest pain which was described as compressive in character, localized, associated with mild shortness of breath and painful swelling in upper part of anterior chest wall. On direct questioning, he mentioned weight loss. Other medical history was unremarkable. On examination, the only abnormal physical sign was the presence of fixed tender swelling over manubrium sterni (2 \u00d7 3 cm).Initial investigations revealed WBC 6,400/\u03bcL, hemoglobin 13.2 g/dl, platelets 324,000/\u03bcL, erythrocyte sedimentation rate 66 mm/hour. Blood chemistry, liver profile, arterial blood gas (ABG) analysis at room air and coagulations studies were within normal limits. A tuberculin skin test was negative. Chest X ray showed large mediastinal mass  and CT cFine needle aspiration of mediastinal mass was done and cytological diagnosis was noninformative. Bone marrow aspiration and trephine biopsy showed normal study. CT-guided biopsy was done, but unfortunately the specimen was crushed and full with artifacts. Open biopsy for mediastinal mass done by cardiothoracic surgeon and histological examination of the tissue obtained showed a malignant tumor that had two cell populations; one consisted of lobules, sheets, trabeculae and clusters of large polygonal cells with nuclei having vesicular chromatin, prominent nucleoli and several mitotic figures. The cytoplasm of those cells was moderately abundant and clear. The other cell population was clusters of small mature lymphocytes, which were scattered within the fibrous septa separating the lobules of the large polygonal tumor cells . ImmunopAbdominal, pelvis and cerebral CT scan; testicular ultrasound and TC-99 MDP bone scintigraphy were negative. Tumor markers: \u03b1 fetoprotein was 2.3 IU/ml  and \u03b2-HCG was < 5 IU/L .Chemotherapy was initiated with B.E.P. protocol ; the patient received four cycles of the drugs. Two weeks after the first cycle, tumor size was reduced markedly. After 8 months, the patient was seen in the clinic; he was well.Germ cell tumors occur most commonly in gonads but infrequently appear in other locations such as mediastinum, retroperitoneum, pineal gland and sacral area; 2-5% of germ cell tumors are of extragonadal origin. It has b2The primary mediastinal seminoma has an estimated incidence of 25% of that of primary mediastinal germ cell tumors and is usually located in the anterior mediastinum,5 with th68The origin of extragonadal germ cell tumors (EGCTs) is still uncertain. The cytogenetic findings on chromosome 12q appear to suggest that extragonadal tumors would be of gonadal origin.Primary seminomas of the mediastinum are unusual neoplasms that are morphologically indistinguishable from their gonadal counterparts but may have different biologic behavior because they arise at this particular location.Histopathologically, germ cell tumors are classified as follows: teratomas (including mature and immature groups), germinomas (seminomas), embryonal carcinoma, choriocarcinoma, yolk sac tumors and mixed germ cell tumors. AlthoughExtragonadal germ cell tumors grow slowly and initially produce few symptoms . Around 30% of patients with mediastinal seminoma were asymptomatic and the mass was discovered incidentally during routine chest X ray.According to the results from an international analysis with 635 cases with extragonadal germ cell tumors, 83% (524) were nonseminomatous and 16% (104) seminomatous germ cell tumors.14In this patient the differential diagnosis of mediastinal seminoma includes teratoma, primary large B cell lymphoma and thymoma. Some features commonly associated with seminoma, such as epitheloid granuloma, cystic changes and lymphocytic infiltration, were not prominent, but the application of immunohistochemical studies showed cytoplasmic staining with placental-like alkaline phosphatase. The application of immunohistochemical studies for placental-like alkaline phosphatase may be of discriminatory value in equivocal case.It is accepted that routine biopsy or orchidectomy is not needed in EGCTs if no evidence exists for retroperitoneal involvement and no abnormality of the testicle is observed.15In our patient a careful clinical and ultrasound examination showed normal testis. Abdominal and pelvis CT showed no evidence of retroperitoneal involvement while brain CT scan was normal.With regard to the treatment of mediastinal malignant GCTs, the current consensus is that initial systemic chemotherapy should be followed by aggressive complete resection of all macroscopic residual tumor when necessary.17Prognosis for patients with mediastinal seminoma is fairly good, with a 5-year survival rate of around 90%. Conversely, nonseminomas have a worse prognosis than seminoma, with a 5-year survival rate of around 45%.14 PatienThus, mediastinal seminoma should be considered in the differential diagnosis of middle, posterior and anterior superior mediastinal mass even in the absence of testicle lesions."}
{"text": "Patient.  A 65-year-old man was admitted with a large primary retroperitoneal            tumor and an increased \u03b2-human chorionic gonadotropin (\u03b2-HCG) serum level. A germ            cell tumor was suspected; however, a computed tomography-guided biopsy failed to enable            tumor classification. After two courses of chemotherapy, the \u03b2-HCG serum level had returned            to the normal level and a diagnostic laparotomy with incisional biopsy was performed.            The immunohistochemical examination of the specimen identified the tumor as a            retroperitoneal pleomorphic leiomyosarcoma.            Discussion. Tumor markers play only a marginal role in the work-up            of patients with soft tissue sarcomas. In men with suspected retroperitoneal sarcomas,            however, the determination of germ cell tumor markers occasionally enables a preoperative          distinguishing of primary retroperitoneal germ cell tumors with considerable consequences          for management. In this setting, a retroperitoneal tumor associated with a moderately          elevated \u03b2-HCG is a diagnostic dilemma, and surgeons should be aware of the pitfall          of a \u03b2-HCG-producing leiomyosarcoma in the differential diagnosis."}
{"text": "Candida species were the most frequent (isolated from 75% of participants), followed by Cladosporium (65%), Aureobasidium, Saccharomycetales (50% for both), Aspergillus (35%), Fusarium (30%), and Cryptococcus (20%). Four of these predominant genera are known to be pathogenic in humans. The low-abundance genera may represent environmental fungi present in the oral cavity and could simply be spores inhaled from the air or material ingested with food. Among the culturable genera, 61 were represented by one species each, while 13 genera comprised between 2 and 6 different species; the total number of species identified were 101. The number of species in the oral cavity of each individual ranged between 9 and 23. Principal component (PCO) analysis of the obtained data set followed by sample clustering and UniFrac analysis revealed that White males and Asian males clustered differently from each other, whereas both Asian and White females clustered together. This is the first study that identified the \u201cbasal mycobiome\u201d of healthy individuals, and provides the basis for a detailed characterization of the oral mycobiome in health and disease.The oral microbiome\u2013organisms residing in the oral cavity and their collective genome\u2013are critical components of health and disease. The fungal component of the oral microbiota has not been characterized. In this study, we used a novel multitag pyrosequencing approach to characterize fungi present in the oral cavity of 20 healthy individuals, using the pan-fungal internal transcribed spacer (ITS) primers. Our results revealed the \u201cbasal\u201d oral mycobiome profile of the enrolled individuals, and showed that across all the samples studied, the oral cavity contained 74 culturable and 11 non-culturable fungal genera. Among these genera, 39 were present in only one person, 16 genera were present in two participants, and 5 genera were present in three people, while 15 genera (including non-culturable organisms) were present in \u22654 (20%) participants.  Candida species were the most frequently obtained genera, isolated from 75% of all study participants, followed by Cladosporium (65%), Aureobasidium, Saccharomycetales (50% for both), Aspergillus (35%), Fusarium (30%), and Cryptococcus (20%). The remaining fungi detected in the oral wash samples represent organisms likely originating from the environment. This is the first study that identified the \u201cbasal mycobiome\u201d of healthy individuals, and provides the basis for a detailed characterization of the oral mycobiome in health and disease.We characterized the fungal microbiome (mycobiome) of the oral cavity in healthy individuals. Our results demonstrate that the fungal component of the oral microbiome is diverse as revealed by the presence of 74 culturable and 11 non-culturable fungal genera in the oral cavity. A total of 101 species were identified, with between 9 and 23 culturable species present in each person. Fifteen genera (which included four known pathogenic fungi and non-culturable organisms) were present in \u226520% of the tested samples;  Candida, are important components of oral microbiota and are influenced by the immune status and therapy of affected individuals, studies of oral microbiota have focused largely on the bacterial components. In the only oral microbiome study to date that included some fungal profiling, Aas et al.Candida albicans and Saccharomyces cerevisiae in the subgingival plaque microbiota of HIV-infected patients. These investigators employed a PCR-based approach using the 18S rDNA primers  to characterize the fungi present in the plaques. The approach used by this group provided only a limited snap shot of the fungal members of the microbial biome.Organisms residing in the oral cavity and their collective genome\u2013the oral microbiome\u2013are critical components of health and disease. Disruption of the oral microbiome has been proposed to indicate, trigger, or influence the course of oral diseases, especially among immunocompromised patients (e.g. HIV-infected or cancer patients) To obtain a more comprehensive profile of the fungal microbiome (mycobiome), in this study we utilized a novel Multitag Pyrosequencing (MTPS) approach to interrogate the fungal taxa in the oral cavity using universal internal transcribed spacer (ITS) primers, which have broad fungal specificity Written informed consent was obtained from all participants in this study. Recruitment of study participants was performed according to protocol (number 20070413) approved by the Human Subjects Institutional Review Board (IRB) of Case Western Reserve University, Cleveland, Ohio.http://www.census.gov), in which race has been classified as White , Black/African-American, Asian, Native American/Native Alaskan etc. Inclusion criteria were: >18 years of age, non-smoking, no recent antifungal use, and no clinical signs of oral mucosal disease. Exclusion criteria were: (1) a history of receiving medication or treatment with topical or systemic steroids, pregnancy, and (2) insulin-dependent diabetes mellitus (IDDM).Oral rinse samples were obtained from 20 healthy individuals after informed consent and following review of the IRB at Case Western Reserve University/University Hospitals Case Medical Center. The individuals were all from the Cleveland area and on standard Western diets. Summary demographic information of the study participants is provided in Concentrated oral rinse has been previously used to detect the presence of oral bacteria and fungi CTTGGTCATTTAGAGGAAGTAA) and unlabeled reverse primer ITS2 (GCTGCGTTCTTCATCGATGC). The ITS primers were selected in this study to detect the presence of various fungi since these primers are able to detect consensus sequences present in a broad range of fungal organisms, and have been used for the detection of yeasts (including Candida spp.), moulds and dermatophytes 2, each dNTP at a concentration of 0.25 mM, each primer at a concentration of 0.5 \u00b5M, and 0.5 U of AmpliTaq Gold DNA polymerase . Initial denaturation at 94\u00b0C for 11 min was followed by 35 cycles of denaturation for 30s each at 94\u00b0C, annealing at 50\u00b0C for 30 s, and progressive extension at 72\u00b0C for 2 min. Following the 35 cycles there was a final extension time of 30 min to minimize artifacts induced by TAQ polymerase. Fungal PCR products were separated on the SCE 9610 capillary DNA sequencer  using GenoSpectrum software to convert fluorescent output into electropherograms. Relative peak abundance of fungal amplicons was calculated by dividing individual peak heights by the total peak heights in a given electropherogram using a custom PERL script. Interleaved, normalized abundances were compared as stacked histograms using Microsoft Excel. Mean normalized abundance for each amplicon was calculated from the three PCR replicates of each sample, excluding means below 1%. Results were analyzed by visual inspection and Principal Coordinate (PCO) analysis using Multivariate Statistical Package . Normalized abundance of each peak in the electropherogram was calculated with respect to the total peak area, since it is not possible to calculate absolute abundances with either the LH-PCR or MTPS technology.The first step in the mycobiome analysis was extraction of DNA from the cell pellet  followed by PCR analysis. Samples were extracted individually using the Fast DNA Spin Kit for fungi following manufacturer's instructions . Each extraction tube was agitated three times using a Fast Prep FP120 instrument at a speed setting of 5 for 30 s. Tubes were cooled on ice between agitations. The ITS1 region from DNA sample extracts was amplified in triplicate using primers with high specificity for ascomycete fungi  technique, which can be used for detailed characterization of nucleic acids and has the advantages of accuracy, flexibility, parallel processing, and easy automation potential We developed a custom PERL script to demultiplex the MTPS data by sorting the sequences into bins based on the barcodes and the taxa in the samples, automatically blasting the pyrosequence data against Genbank . The annotations for each sequence were downloaded and a PERL script used to tabulate the taxa as a percentage of the total oral community in each sample. Fungal ITS sequences were compared with the Assembling Fungal Tree of Life (AFTOL) database using the BLAST interface of Web Accessible Sequence Analysis for Biological Inference (WASABI) as well as against the NCBI nucleotide database.Principal Coordinate (PCO) analysis has been recognized as a simple and straight-forward method to group or separate samples in a dataset, and has been used in disease-association studies http://bmf2.colorado.edu/unifrac/index.psp). The analysis was weighted using the abundance of the sequence in each cluster. The P-value generated from the UniFrac significance test describes the degree of similarity between classes. Values reported were Bonferroni corrected for the number of sequences used in comparisons.To compare the phylogenetic distribution between the various gender and race classes and confirm the results of PCO analysis, we used UniFrac significance test The demographic characteristics of the study participants were: 21\u201360 years of age, 8 females and 12 males, no history of smoking, insulin-dependent diabetes mellitus, or active medications; the self-reported ethnicities of study participants were White , Asian  , or African-American . All participants were from the metropolitan Cleveland Ohio area, and were Faculty, staff or students at Case Western Reserve University . Study pCandida (15/20), Cladosporium (13/20), Aureobasidium (10/20), and organisms belonging to the family Saccharomycetales (10/20). Interestingly, a large percentage (36.1%) of fungi belonged to non-culturable category. The minimum number of genera identified in a sample (sample E3) was 3 , while the maximum number of genera identified was 16 in sample A2, which included Candida (5.5%), Dothediomycete (10.7%), Fusarium (4.1%), Aspergillus (3.9%), and Xylariales (7.7%)  were longer than 100 bases and were used in the analysis. Our analyses revealed an average of 1,702 sequences per sample with an average length of 248 bases . A locals (7.7%) . The nonCandida species were the most frequently obtained genera, isolated from 75% of all study participants, followed by Cladosporium (65%), Aureobasidium and Saccharomycetales (50% for both). Other fungi that were present in the oral cavity of healthy individuals were Aspergillus (35%), Fusarium (30%), and Cryptococcus (20%). Fifty three percent (39/74) of the identified genera were observed only once in the tested samples.To determine the basal fungal distribution in healthy individuals, we identified fungi that were present in at least 20%  of the study participants. This analysis revealed that 15 genera were present in \u226520% of the tested samples , followed by Candida (5 species), Cladosporium (4 species), Fusarium (3 species), and Penicillium (3 species) , while the non-albicans Candida species indentified were: C. parapsilosis (15%), C. tropicalis (15%), C. khmerensis and C. metapsilosis (in 5% of the subjects). Two species each of Alternaria, Cryptococcus, Ophiostoma, Glomus, Phoma, Schizosaccharomyces, and Zygosaccharmoyces were identified in the participants.Analysis of the species distribution of the oral mycobiome revealed that 12 fungi were represented by two or more species in the oral rinse samples  . CandidaTo investigate whether there is an association between any of the subject demographics and changes in mycobiome, we performed PCO analysis and sample clustering followed by UniFrac analysis. Our analysis revealed that White and Asian males clustered differently from each other, whereas both Asian and White females clustered together . UniFracIn the current study, we demonstrated the presence of 74 culturable and 11 non-culturable fungal genera in the oral cavity of healthy individuals, with between 9 and 23 culturable species present in each person, representing a total of 101 species for all study participants.Candida; rather it is represented by a large number of diverse fungi. The perception that fungi in the oral cavity are limited to only few species originated from previous studies that relied upon the use of culture-based methods or species-specific targeted PCR approach. In addition to Candida, other fungi previously reported in the oral cavity include S. cerevisiae, Penicillium, Geotrichum, Aspergillus, Scopulariopsis, Hemispora, and HormodendrumOur results demonstrate that the fungal component of the oral microbiome is not limited to a few species, principally et al.Only two previous studies have investigated the profile of microbes present in the oral cavity of healthy individuals and both focused on the bacterial microbiome et al.S. cerevisiae in 4 and C. albicans in 2 patients. No other fungal species were detected in analysis of 306 18S rDNA clones. In contrast, we found that the oral cavity of healthy individuals had 101 fungal species. The reason for this difference could be attributed to differences in: (a) sampling method \u2013 oral rinse versus sub-gingival plaque; oral rinse enables the collection of organisms from the dorsum of the tongue as well as from the ever changing oral mucosal environment as compared to the sub gingival biofilm plaque, (b) detection probe \u2013 18S rDNA probes that detected Candida and eight other genera, versus the pan-fungal ITS1/ITS2 probe that could identify all fungi, and (c) sequencing technique \u2013 cloning of rDNA fragments followed by sequencing, versus real-time pyrosequencing.While the fungal component of the oral cavity has not been investigated in healthy individuals, a previous study identified fungi present in the oral cavity of HIV-infected patients et al.We also found that the distribution of fungal species varied greatly between different individuals. Similar variation was recently reported for bacterial microbiota by Nasidje Candida (present in 75% of the cohort), Aspergillus (35%), Fusarium (30%), and Cryptococcus (20%). While the abundance of Candida in these healthy individuals was not surprising, the actual percentage was higher than reported in earlier culture-based studies, where 40 to 50% of healthy individuals have been shown to contain Candida species in their oral cavity Candida detected in this study could be attributed to the use of the more sensitive ITS/pyrosequencing approach. Another interesting finding was the different types Candida species identified in the oral cavity of healthy individuals. The most abundant Candida species in this study was found to be albicans (in 40% of the subjects), followed by C. parapsilosis (15%), C. tropicalis (15%), C. khmerensis (5%) and C. metapsilosis (5%). These results are in agreement with those reported by earlier studies using culture-based as well as PCR-based analyses The oral mycobiome of at least 20% of the enrolled individuals included the four most common pathogenic fungi \u2013 Aspergillus, Fusarium, and Cryptococcus isolates in the oral cavity of healthy individuals was unexpected, since these fungi have not been reported to be colonizers of the oral cavity. It is possible that the pathogenicity of these fungi is controlled in healthy individuals by other fungi in the oral mycobiome, as well as a functional immune system. It is possible that inter-dependent relationships may exist between components of the oral mycobiome, and need to be investigated using broader sampling and longitudinal studies.The presence of In our studies, we also identified 60 fungal genera that are ubiquitous in the environment  and not normally associated with infections. Among these genera, 39 genera occurred once among the 20 samples analyzed, 16 genera occurred with a frequency of 2, while 5 genera occurred in three individuals. Due to their ubiquitous nature, the presence of these organisms in the oral cavities of healthy individuals was not surprising, which are most likely of environmental origin, from food and mouth breathing.et al.In this study, non-culturable fungi represented a large percentage (36.1%) of the organisms identified in the oral mycobiome of healthy individuals. This is the first study demonstrating the presence of non-culturable fungal organisms in the oral cavity, which may play important role in the oral milieu. The presence of non-culturable organisms has been reported for bacterial species in the oral cavity; about half the population of oral bacteria has been reported to be non-culturable. For example, Aas http://nihroadmap.nih.gov/hmp/)\u201d. Results from our study provides critical information that is likely to form the basis of further \u201chypothesis-driven\u201d studies evaluating the oral mycobiome in terms of individual variabilities, longitudinal trends, and the effect of diet and geography, and studies focused on determining the association of oral mycobiota with health and disease.Ours is the first study that provides a snapshot of the oral mycobiome in various individuals, and addresses an important component of the Human Microbiome Project (HMP). Since this is the first study that identifies the oral mycobiota, our findings complement the HMP  and support its stated goal of \u201cgenerating resources enabling comprehensive characterization of the human microbiota and analysis of its role in human health and disease  in an individual could be the first step in predisposing the host to opportunistic infections. In this regard, oral Candida colonization has been known to be a risk factor for Candida infections in immunocompromised patients The clinical relevance for the presence of a diverse population of fungal species in the oral cavity is unknown. It is possible that the presence of a given fungal isolate (e.g. Table S1Sequence data(1.15 MB ZIP)Click here for additional data file.Table S2Frequency distribution of fungi belonging to different genera present with at least one percent abundance in the oral mycobiome of healthy individuals(0.05 MB XLS)Click here for additional data file.Table S3Species distribution of fungi present in oral cavity of healthy individuals(0.05 MB XLS)Click here for additional data file."}
{"text": "Environ Health Perspect 122:100\u2013106 (2014)], there was an error in Table 1. The number of women in exposure quartile 4 who had missing data for maternal smoking was given as zero instead of 3. The corrected table appears below and has also been corrected online.In the article \u201cExposure to Brominated Trihalomethanes in Water During Pregnancy and Micronuclei Frequency in Maternal and Cord Blood Lymphocytes\u201d by Stayner et al. [EHP regrets the error."}
{"text": "Jasus edwardsii, shows clear phenotypic differences between shallow water (red coloured) and deeper water  individuals. Translocations of individuals from deeper water to shallower waters are currently being trialled as a management strategy to facilitate a phenotypic change from lower value pale colouration, common in deeper waters, to the higher value red colouration found in shallow waters. Although panmixia across the J. edwardsii range has been long assumed, it is critical to assess the genetic variability of the species to ensure that the level of population connectivity is appropriately understood and translocations do not have unintended consequences. Eight microsatellite loci were used to investigate genetic differentiation between six sites  across southern Tasmania, Australia, and one from New Zealand. Based on analyses the assumption of panmixia was rejected, revealing small levels of genetic differentiation across southern Tasmania, significant levels of differentiation between Tasmania and New Zealand, and high levels of asymmetric gene flow in an easterly direction from Tasmania into New Zealand. These results suggest that translocation among Tasmanian populations are not likely to be problematic, however, a re-consideration of panmictic stock structure for this species is necessary.The southern rock lobster,  Human-mediated movement of species, known as translocation or assisted migration, is increasing in popularity as a strategy to maintain species abundance, connectivity and diversity. Translocation has been used commonly throughout agricultural history, and it is currently also an important conservation strategy for threatened species ,2. SucceJasus edwardsii), to determine if it was possible to improve value and productivity of the Australian stock [Pilot translocations were trialled in the southern rock lobster  Iacchei et al [P. interruptus also possesses a long larval duration (240-330 days) [Phenotypic differences between shallow and deep populations of the southern rock lobster are due to differences in habitat, and are not genetic, as pilot studies have shown that translocated, pale individuals change to the more desired phenotype after a single moult ,8. Althoei et al  show sli30 days) . Indeed 30 days) -14.Like many marine species with long larval phases, the southern rock lobster has long been assumed to be panmictic throughout the range of Australasia -17. KnowThis study aims to use microsatellite markers to investigate genetic differentiation among Tasmanian populations of the southern rock lobster, where translocations are under consideration as an ongoing management strategy. Analysis of genetic structure is evaluated at different levels, including between 1) shallow and deep water populations, 2) fine scale geographic separation of Tasmanian populations and 3) the oceanic divide of Tasmania and a New Zealand site. This will help to determine if current translocation efforts stand to negatively impact the southern rock lobster, and if there is significance in the scale and directionality of connectivity for this species. Potential patterns in connectivity and source-sink recruitment relationships may be important in the appropriate management and success of translocation for this species in the future.Lobsters were sampled from six sites across the southern coast of Tasmania, and one site from New Zealand (NZ) . All hanBaited traps deployed and collected from research and commercial vessels were used to catch lobsters. All handling of Tasmanian rock lobsters in this study met the Australian Government National Health and Medical Research Council code of practice for the care and use of animals for scientific purposes. Although currently ethics approval is not required for research on invertebrates under this code of practice, the guidelines for ethical and humane treatment of animals in research were followed in all handling of lobsters. Sampling of rock lobster did not involve interactions with endangered or threatened species. Three shallow water sites sampled , were between 0 and 30 metres water depth, and comprised of lobsters with red coloured phenotypes. Three deep water sites sampled  were greater than 60 metres in depth, and were largely populated by pale coloured lobsters. Distances between sample sites (by sea) range from 10 km (between EP and MBI) to 220 km apart (between HI and TAR). We considered the effects of geographic and oceanic distance, between shallow and deep populations and any potentially resulting genetic patterns on subsequent translocations within the stock.Samples of rock lobster in Taroona reserve were collected on 1-4 February 2012 . A clip of tissue from the pleopod was stored in 95% ethanol, and the lobster released. Pleopod tissue samples from other Tasmanian sites were collected from 15 January to 15 February 2012. In addition, tissue samples were taken from lobsters collected from Taieri Mouth, Otago Harbour and Moeraki on the south island of New Zealand  during AJ. edwardsii  for capillary separation. Results were carefully scrutinised by eye using GENEIOUS PRO version 5.6.4 , using tBinned genotypes scored were formatted in GENALEX version 6.4 . MICRO-CPairwise F-statistics (Fst's) were calculated in FSTAT between assigned groups of individuals. Fst's were tested by hierarchical comparisons between: 1) all populations, 2) shallow water and deep water groups and 3) paired groups of Tasmania and New Zealand.STRUCTURE version 2.3.4 , was useBAYESASS version 3.0.1  was usedhttp://doi.org/10.5061/dryad.656gf). A total of 460 individuals were genotyped for eight microsatellite loci. Despite numerous attempts to optimise PCR conditions for all nine microsatellite loci from Thomas and Bell , locus JA significant frequency of null alleles were detected from loci JE_01, JE_LZ, JE_17, JE_40 and JE_07 using MICRO-CHECKER , althougAllelic richness for each population was similar  . TAR, HIF-statistics were used to compare across 1) all populations, 2) solely between Tasmanian populations and 3) between red  and pale (deep) populations of Tasmania. After Bonferroni correction, the data set indicated a significant difference between NZ and the six Tasmanian populations, the largest oceanographic distance compared (Fst=0.0290-0.0342) . Fst anaWhen Tasmanian populations were combined and compared to the NZ population in a pairwise Fst test, analysis showed significant levels of differentiation (Fst=0.0305) over this large distance. When populations from Tasmania only were compared by grouping the three shallow populations and the three deep populations in a pairwise analysis, no significant difference was detected. Overall, F-statistics indicated a significant difference between Tasmanian and New Zealand individuals, and a small yet still significant level of differentiation among some populations of Tasmania, yet no consistent differences between shallow and deep populations.An analysis of clusters in STRUCTURE revealed no clear grouping of individuals sampled . GroupinDAPC was tested on all individuals with a best fit for clusters found at K = 4 . The majAnalysis using STRUCTURE and DAPC suggested some level of differentiation present between individuals from Tasmania compared to New Zealand, however, no fine scale structuring was noted amongst populations of Tasmania, which suggested a high level of admixture between populations.Evaluation of migrants or admixture between populations was analysed using BAYESASS on hierarchical levels of 1) between all populations and 2) between combined populations of Tasmania and New Zealand. BAYESASS permits migration rates to be asymmetric but they must be small, the number of migrants per generation must not exceed a third, and in scenarios with low genetic differentiation (Fst<0.02) the program will struggle to define resulting migration patterns . A pairwTo take into consideration any effects of unequal number in sample sizes, pairwise comparisons of each individual Tasmanian population were run against the New Zealand population. Results showed no differences except that New Zealand was shown to realistically contribute closer to 1-3% of migrants to Tasmania . BAYESASPilot scale translocations of lobsters from deep to shallow waters around the southern coast of Tasmania and Southern Australia were financially and biologically beneficial ,7,8,47. J. edwardsii should not be disregarded completely. Rather, more complete sampling across the Tasmanian coast and Australia in general is required for a more definitive conclusion on genetic stocks. Detailed studies of population structure have not yet investigated patterns of genetic structure across Australia. The need for further study on Tasmanian populations, and the genetic stock structure of J. edwardsii across Australia is emphasised by the recent study of New Zealand populations [J. edwardsii was not homogeneous throughout its range in New Zealand, and rejected the null hypothesis of panmixia [There is minor evidence of some population structure, with low, yet statistically significant individual pairwise comparisons between some Tasmanian sites. With Fst values <0.003, it is probable that these values are not biologically significant ,49, howeulations . Thomas panmixia , althougNevertheless, finding statistically significant differences in pairwise comparisons of populations is not sufficient enough to confidently conclude that such populations are demonstrating an important level of genetic sub-structuring . StatistJ. edwardsii that are supported by models of larval trajectories that suggest trans-Tasman dispersal from Australia to New Zealand [J. edwardsii and J. novaehollandiae (based on minor differences in morphology) [Assumptions of population panmixia between Australia and New Zealand  appear t Zealand . The undphology) , until ephology) . As somephology) ,16, the J. edwardsii across its entire range of southern Australia and New Zealand. There is evidence that gene flow between distant populations does not occur equally in both directions; with both the results of this study and those of Thomas 2012 [This study provides a detailed investigation of the populations of southern Tasmania, some of which are currently involved in translocation projects. Clearly though it represents only a preliminary study of mas 2012 , suggestGiven the significant influence ocean currents have been suggested to have on population differentiation between Tasmania and New Zealand, they may also play a significant role in determining population connectivity amongst Australian populations. Migration rates were unable to be appropriately resolved between the sampled populations across Tasmania, clearly indicating important gaps in sampling that could have led to a determination of the level of self recruitment, or source stocks for southern Tasmania. Hydrological and gene flow modelling suggests a dominant eastward flow of the transport of larvae between populations , which fThere are a number of large currents across the expanse of southern Australasia that suggest source-sink relationships and an easterly pattern of step wise recruitment driving gene flow in this species . Given tThis analysis did not identify any scale of population structure that would suggest any genetic differences between shallow (red) and deep  populations. There is a significant level of genetic differentiation between Tasmania and New Zealand, and therefore the assumption of widespread population panmixia can be rejected. Although large scale translocations are genetically viable in this region of Tasmania, it is important to understand that if the indications of asymmetric gene flow and population differentiation found are transferable across the rest of this species range, then translocations should only be undertaken on a local scale. Similarly, finding significant genetic structure in an important fishery species, where previously none had been identified, means a much more detailed assessment of lobster connectivity across the range may find more unique genetic stocks, and important source sink relationships which will have important implications for successful translocations and stock structure management schemes. Given these findings, further research in this area is essential, as current management of the southern rock lobster fishery reflects national and state boundaries rather than the species biology.Figure S1STRUCTURE assignment of individuals across all populations into clusters of K=2.Colours indicate percentage contribution of individuals to assigned clusters (y axis), individuals represented by each line (x axis), black lines separate populations from which individuals belong. TAR, Taroona Reserve; MBI, Mutton Bird Island; HI, Hobbs Island; MAT, Maatsyuker Island; CQE, Cape Queen Elizabeth; EP, East Pyramids; NZ, New Zealand.(TIF)Click here for additional data file.Table S1Estimates of null allele frequencies across all populations by loci.Significant frequencies of greater than 10 percent null alleles indicated in bold. TAR, Taroona Reserve; MBI, Mutton Bird Island; HI, Hobbs Island; MAT, Maatsyuker Island; CQE, Cape Queen Elizabeth; EP, East Pyramids; NZ, New Zealand.(DOCX)Click here for additional data file.Table S2Fst's across all populations without locus JE_07.Data set of Fst values. Bold indicates significant values of p value <0.05, * indicates significant values after Bonferroni correction of p<0.002381. TAR, Taroona Reserve; MBI, Mutton Bird Island; HI, Hobbs Island; MAT, Maatsyuker Island; CQE, Cape Queen Elizabeth; EP, East Pyramids; NZ, New Zealand.(Table S2.1) Fst's across all populations without locus JE_17.Data set of Fst values. Bold indicates significant values of p value <0.05, * indicates significant values after Bonferroni correction of p<0.002381. TAR, Taroona Reserve; MBI, Mutton Bird Island; HI, Hobbs Island; MAT, Maatsyuker Island; CQE, Cape Queen Elizabeth; EP, East Pyramids; NZ, New Zealand.(Table S2.2) Fst's across All Populations without Locus JE_01Data set of Fst values. Bold indicates significant values of p value <0.05, * indicates significant values after Bonferroni correction of p<0.002381. TAR, Taroona Reserve; MBI, Mutton Bird Island; HI, Hobbs Island; MAT, Maatsyuker Island; CQE, Cape Queen Elizabeth; EP, East Pyramids; NZ, New Zealand.(Table S2.3) Fst's across all populations without loci JE_07, _17 and _01Data set of Fst values. Bold indicates significant values of p value <0.05, * indicates significant values after Bonferroni correction of p<0.002381. TAR, Taroona Reserve; MBI, Mutton Bird Island; HI, Hobbs Island; MAT, Maatsyuker Island; CQE, Cape Queen Elizabeth; EP, East Pyramids; NZ, New Zealand.(DOCX)Click here for additional data file.Table S3Migration rates (posterior probabilities) across all populations.Bold/italicised values indicate self recruitment, left column indicates where migrants travelled to, top row indicates where migrants originated from. TAR, Taroona Reserve; MBI, Mutton Bird Island; HI, Hobbs Island; MAT, Maatsyuker Island; CQE, Cape Queen Elizabeth; EP, East Pyramids; NZ, New Zealand.(DOCX)Click here for additional data file.Table S4Migration rates (posterior probabilities) compared between each Tasmanian population and New Zealand.Bold/italicised values indicate self recruitment, values in parentheses indicate standard deviation, left column indicates where migrants travelled to, top row indicates where migrants originated from. TAR, Taroona Reserve; MBI, Mutton Bird Island; HI, Hobbs Island; MAT, Maatsyuker Island; CQE, Cape Queen Elizabeth; EP, East Pyramids; NZ, New Zealand(DOCX)Click here for additional data file."}
{"text": "Limited communication resources have gradually become a critical factor toward efficiency of decentralized large scale multi-agent coordination when both system scales up and tasks become more complex. In current researches, due to the agent\u2019s limited communication and observational capability, an agent in a decentralized setting can only choose a part of channels to access, but cannot perceive or share global information. Each agent\u2019s cooperative decision is based on the partial observation of the system state, and as such, uncertainty in the communication network is unavoidable. In this situation, it is a major challenge working out cooperative decision-making under uncertainty with only a partial observation of the environment. In this paper, we propose a decentralized approach that allows agents cooperatively search and independently choose channels. The key to our design is to build an up-to-date observation for each agent\u2019s view so that a local decision model is achievable in a large scale team coordination. We simplify the Dec-POMDP model problem, and each agent can jointly work out its communication policy in order to improve its local decision utilities for the choice of communication resources. Finally, we discuss an implicate resource competition game, and show that, there exists an approximate resources access tradeoff balance between agents. Based on this discovery, the tradeoff between real-time decision-making and the efficiency of cooperation using these channels can be well improved. Communication resources always play a latent role in networked large-scale agent team coordination applications, such as multi-robots system, mobile sensor system, etc. With the expansion of the system, communication resources exert a momentous impact on the cooperative efficiency , and numAs a main technical part of our research. In this paper, we model the decentralized multi-agent multi-channel access problem as a Decentralized Partially Observable Markov Decision Process (Dec-POMDP) problem. We use a continuous time Markov model to simulate the usage of channels while the constant slotted opportunity is used to support agents\u2019 interaction. In addition, we use a sample-based Partially Observable Markov Decision Process (POMDP) to simplify the model. Finally, based on game theory, we model and analyze implicit resource competition between agents, and prove the existence of equilibrium in an ideal state.Even though centralized channel resource allocation methods can provide some sort of optimal solutions, they are less effective in situations where the central point fails. For instance, typical auction-based algorithms generally have low communication requirements , and theOpportunistic Spectrum Access (OSA)  and OppoGame Theory provides another approach to OSA. Stochastic game  as an exMany existing works assume that the observation information obtained from an agent\u2019s neighbors is highly correlated. It can improve the efficiency of multi-agent coordination. In this case, exchange of local observations becomes important in coordination. From this view, we present a decentralized cooperative game model in which agents can iteratively adapt their strategies in terms of reduced competition or conflict, and can meet the minimum communication requirements for each agent timely. This presents a novel approach addressing the gaps in the aforementioned works.In this section, we follow the basic idea of continuous time Markov model to define the basic model of a multi-Channel access problem, and then describe the specific functional definition of each variable and the decision model.N distributed agents. Although the multi-hops information sharing method can make each agent finally gain full knowledge of the global state, this consumes a lot of communication resources and also deteriorates the system\u2019s performance. Therefore, an agent makes decisions based on its limited observations, and the entire system would still be partially observed. The network consists of a set of contiguous, orthogonal (non-interfering) and homogeneous channels , denoted by CH = {c1, c2, \u2026, cK}. The available channels are also numbered from 1 to K, and we assume that N > K agents are seeking channel opportunities in these K channels.We consider a multi-agent Ad-hoc network as being created by agents themselves in an open environment, with set ri can sense a set of channels and a subset of sensed channels to access. Limited by its hardware constraints, ri can sense {C1} channels,  channels and access {C2} channels,  channels. State statistics of the K channels follows a discrete-time Markov process with 2K states, where state is either idle or occupied. The channel sensing and access decisions are made to maximize agents reward by fully exploiting the sensing of vacant opportunities and the history statistics.We should recognize that agents can only access channels if the sensed channels are idle. As shown in For some reasons, some agents change the status of stable channel access, and other agents need to adjust the channel access based on their limited observation so as to ensure the global rational use of resources and QoS. Therefore, the multi-agent multi-channel access problem can be described as cooperative searching for available resources in a partially observable multi-channel network. As such, this can be modeled as a Dec-POMDP problem in terms of interdependence. A finite-horizon Dec-POMDP can be defined as a tuple S = {s0, s1, \u2026sn} denotes the finite set of network states.Ai = {a1, a2, \u2026, am} denotes ri\u2019s available actions set. At each time step, all the agents in T denotes Markovian state transition function. P denotes the probability that doing action \u039bt and being in state s then going to state s\u2032.ri at time t.O denotes observation function, which specifies the probability of joint observation O.t in state s.p0 = {B0, s0} is the initial belief and state distribution.a is determined by the policy \u03c0: b\u2192a, which is the function that maps a belief state to the action that an agent should execute. i \u2264 t\u221211 \u2264 {\u03c9t\u22121} denotes the known network states.Action Qi to denote the possible policy space for agent ri, and Qi\u2212 denotes the sets of policy trees for all agents except ri. With a programming approach, it is required that we generate incrementally the sets of useful policies for each agent. Thus, a joint policy \u03a0 = \u00d7i \u2208 N{\u03c0i} is a vector of policy trees. Evaluating a joint policy can then use the following formulation:\u03c9) is the joint policy of subtree selected after observation \u03c9. So we get the utility function as:Formally, most policies can be represented as decision trees. We use n policies to maximize a total reward function from finite horizon T under initial belief state p0, and the expected joint reward is given by Therefore, the essence of this framework is to find a set of no-information-sharing.In this section, we demonstrate an agent\u2019s decision-making process based on current observation and resource perception, and analyze the computational complexity under the instincts of Shannon\u2019s theory .We can use  use Eqs  and 6)  pi,jp anesign in :U=ri cannot get a full view of the state of the system, since it can only use its observation to update its actions. The goal of this problem\u2019s model is to come up with a joint policy \u03a0* = ri can only infer what action its neighbors may take, but the inference or conflict is inevitable. At each time slot, we can compute the expected value of a policy as follows:Based on the model described above, agent tatistic , and canT policy tree searching process.Solutions to a finite-horizon POMDP can be represented as a decision tree, where nodes denote the actions and arcs denote the observations. Similarly, solving a finite-horizon Dec-POMDP with known state space can be formulated as a multiple vector of horizon Algorithm 1: Resource aware policy search for agent ri.Require:g0 = 0; \u211c0 = {\u03a6}; \u211c \u2208 Qi;\u2003Set Ensure:\u2003foreachrido1: randomselectploicycandidatesset {\u03b7i}from \u211c;2:\u2003 gi(t) = 3:\u2003 forall\u03c0i \u2208 \u03b7ido4:\u2003 excute\u03c0itoobtain\u03c9t;5:\u2003\u2003 computegi(t);6:\u2003\u2003 ifthen7:\u2003\u2003 \u03c0* = \u03c0i;8:\u2003\u2003\u2003 else9:\u2003\u2003 i and get newprune \u03c010:\u2003\u2003\u2003 end if11:\u2003\u2003 argmax {\u03a0\u2032 \u2208 \u211c|V(\u03b7\u2032) > R(\u03b7)};12:\u2003\u2003 end for13:\u2003 return\u03c0* \u2192 \u03a0*;14:\u2003 end for15: Qi denotes the random initialized policy space with completely unspecified candidate policies. gi = \u03b70 from \u211c, if gi\u2019s value is bigger than \u03c0i to \u03c0i and search new lower bound for an optimal joint policy, which can be used to prune the search space. If ri has the minimum gi value in one round, then it will get priority to access its {C2}. Other agents are constantly updated to the new strategy, and after finite times evaluation and exploration that they can get all the apposite policies to fix the gi value. In a limited belief space, by retrieving the limited policies space, and the state transition probability approaching the optimal values, similarly, the decision can approach the optimal policy gi performs a summation over all possible network states and observations, and so the time complexity of this algorithm is O((|S|\u22c5|Qi|)T). The value of a policy is highly dependent on the other agents\u2019 beliefs and the current system status, whereas, without sharing, the policy regeneration can only be derived on the basis of the reckoned joint policies. We define the policy update function as:\u039e\u03c0 represents the conditional expectation given that policy \u03c0i is employed, and B0 is the initial belief, which can be the stationary distribution of the network state. \u03c9t and the known status ri is As shown in Algorithm 1, \u211c \u2208 ri can get a proximate full local observation. Consequently, we refer to the design in . X-axis represents the agents\u2019 number. As in In this simulation, we test the average available channel resources for the new accessed agents under different interaction frequencies of the other agents in the network. We set 5 channels and 100 per slot new accessed agents, which are uniformly distributed in these 5 channels, the max agents number is 1000. The interaction frequency of the other agents was set to According to the experiment\u2019s results, we can make a bold hypothesis that while the number of agents and the resource relatively balance, there should be a suitable interaction frequency that makes each agent obtain available resources to maximize its utility.In this simulation, we discuss the relationship between different team sizes when agents access channels under different assignment. We divide 100 agents into different team sizes, and allow them to access 5 channels. Simulation results are shown in Obviously, we can see that when the combination in each channel distribution is more uniform, the greater resource available, as assignment  and . In an extreme access situation with , all agents are in one channel. When communication demand escalates, all agents almost have no chance to obtain available resources. From above analysis, we can conclude that agents will gain more available resources when they distribute more uniformly.It can be seen that, with 500 tests for the same channel (distribution within the circles), agents can obtain the actual state of the channel. The red trail denotes the search result by POMDP, and black trail denotes the RANDOM method. It is obvious that the randomness and divergence of RANDOM far outweigh that of POMDP.We assumed in this paper that channel state transition probabilities can be entirely perceived, but in practice, this may not be available. The problem then becomes a decision model with unknown transition probabilities, but such mode is beyond the scope of this paper. In our design, we reduce a Dec-POMDP model to a simplified one by separating the problem into single-agent decision coordination, which may result in a low-complexity but potentially suboptimal design. In practical applications, systems Dynamics making use of pure policy space searching to solve all the problems become impractical, and need to be adjusted according to the actual situation and dynamics, and add more factors. In our future work, we will pursue the optimal joint design of the tradeoff between complexity and optimality, and will apply reinforcement learning theory on real multi-robots platform.S1 Table(XLS)Click here for additional data file.S2 Table(XLS)Click here for additional data file.S3 Table(XLS)Click here for additional data file.S4 Table(XLS)Click here for additional data file.S5 Table(XLS)Click here for additional data file.S1 File(DOC)Click here for additional data file."}
{"text": "The Na-H exchanger [NHE] performs an electroneutral uptake of NaCl and water from the lumen of the gastrointestinal tract. There are several distinct NHE isoforms, some of which show an altered expression in the inflammatory bowel diseases (IBD). In this study, we examined a role of NHE-2 in experimental colitis.Colitis was induced in male Sprague-Dawley rats by intra-rectal administration of trinitrobenzenesulphonic acid (TNBS). On day 6 post-TNBS, the animals were sacrificed, colonic and ileal segments were taken out, cleaned with phosphate buffered saline and used in this study.in vitro TNF-\u03b1 treatment of uninflamed rat colonic segment. These changes were selective and localized to the colon as actin, an internal control, remained unchanged. Confocal immunofluorescence microscopy revealed co-localization of NHE-2 and NHE-3 in the brush borders of colonic epithelial cells. Inflamed colon showed a significant increase in myeloperoxidase activity and colon hypertrophy. In addition, there was a significant decrease in body weight and goblet cells\u2019 mucin staining in the TNBS treated colon. These changes were not conspicuous in the non-inflamed ileum.There was a significant decrease in the level of NHE-2 protein as measured by ECL western blot analysis and confocal immunofluorescence microscopy. The levels of NHE-2 mRNA and heteronuclear RNA measured by an end-point RT-PCR and a real time PCR were also decreased significantly in the inflamed colon. However, there was no change in the level of NHE-2 protein in response to These findings demonstrate suppression of NHE-2 expression on the brush borders in the colonic epithelial cells which is regulated transcriptionally. However a role of TNF-\u03b1 in the regulation of NHE-2 is discounted in the present model of colitis. This decrease in the NHE-2 expression will lead to a loss of electrolyte and water uptake thus contributing to the symptoms associated with IBD. The NHEkappa-B [NF-kB] binding site makes it respond to proinflammatory cytokines, infectious agents, and oxidative stress. Therefore, high levels of pro-inflammatory cytokines, such as interferon-\u03b3 [IFN-\u03b3], tumor necrosis factor-\u03b1 [TNF-\u03b1] in IBD might regulate NHE-2 expression leading to alteration in the secretion and absorption of electrolytes in the inflamed colon  solution containing 30 mg TNBS dissolved in 250 \u03bcl of 50% ethanol intra-rectally about 8 cm from the anal margin, and the control group in which each animal received phosphate buffered saline [PBS] in a similar fashion \u201325. The 2O2 converted to water per min per mg tissue.Colitis was characterized by measuring myeloperoxidase activity [MPO] following standard methods \u201325. TissBody weight [BW] of each animal was recorded before induction of colitis on day 0 and on day 6 post-TNBS just before sacrifice. Changes in the BW on day 6 were calculated with respect to their initial BW at day 0. Colon length and weights without feces were also measured on day 0 and day 6 post-TNBS, and colon hypertrophy was expressed as weight [mg] per cm length.Standard methods were used to fix tissues in paraformaldehyde and for embedding in paraffin blocks . Colon sTissue segments were chopped finely with scissors using 10 ml [per gm tissue] of ice cold MOPS-sucrose (3 [N-Morpholino]propanesulfonic acid) buffer, pH 7.4 \u201325. The The samples containing 2\u20133 mg/ml protein were prepared using a 4 x sample buffer, heated in a boiling water bath for 5 min and then transferred directly onto an ice bath before loading onto an 8% polyacrylamide gel. The buffer and gel solutions were prepared following methods as used earlier in this laboratory \u201325. LysaLevels of NHE-2 protein were estimated by measuring the fluorescence units obtained by confocal immunofluorescence microscopy. Paraformaldehyde fixed colonic tissues were embedded in paraffin to prepare paraffin blocks. Tissue sections [7 \u03bcm thickness] were placed onto glass slides, deparaffinized, dehydrated and rehydrated using graded ethanol solutions . SectionTo understand the underlying mechanism of NHE-2 protein expression we quantitated the levels of NHE-2 transcript. Two approaches, an end-point cycle RT-PCR and a SYBR-green real time RT-PCR were used to estimate the level of NHE-2 mRNA. For this purpose upstream [PR1] and downstream [PR2] primers were designed using a published NHE-2 cDNA sequence . The mRNAn aliquot of total RNA (1\u03bcg) was reverse transcribed using 1 pmol of PR3 primer using a single step RT-PCR kit [Amersham], and subsequently amplified for 28 cycles using the primers PR1 and PR2 [100 pmoles each]. The following cycle settings were used: denaturation [94\u00b0C x 30 sec]; annealing [55\u00b0C x 30 sec]; extension [74\u00b0C x 30 sec]. The PCR product  was separated by the agarose gel electrophoresis, and purified. An optimal concentration of the purified CC measured separately was used to spike each sample for its co-amplification with the NHE-2 transcript. This process was called as competitive RT-PCR method because the same set of primers were used to amplify both the target and the control. In this method variations dependent on the structure and composition of the primers, the target and the control are minimized, and hence this quantitation is more accurate than the normal RT-PCR in which a house-keeping gene is amplified using two different sets of primers.Total RNA from rat colon was extracted using a Trizol RNA extraction kit following instructions from the supplier [GIBCO]. Concentration and purity of total RNA were estimated from optical densities obtained at 260 and 280 nm using a spectrophotometer [Pharmacia].The quality of total RNA was assessed using a formaldehyde agarose gel electrophoresis and a nano-drop method . An aliquot of total RNA [5\u201310 \u03bcg] was mixed with an equal volume of 2 x RNA buffer [Ambion] and heated at 80\u00b0C for 5 min. The samples were then separated electrophoretically on a 1.4% agarose gel containing 1% formaldehyde, or on 8% polyacrylamide gel as described earlier , 24\u201325. Different concentrations of CC were used to obtain an optimal concentration for quantitation. A known optimized concentration of CC was then used to spike both the control and colitis samples, and co-amplified by 28 cycles. Individual densities of both the target and the CC bands was obtained from each lane, and a ratio of NHE-2:CC was calculated. This ratio was therefore used to express the level of NHE-2 mRNA in this study. This data was further confirmed using a SYBR green real time PCR method.An aliquot of total RNA [1\u03bcg] was mixed with the primers PR1 and PR2 [100 pmoles of each], buffer and 1 unit of Platinum Taq DNA polymerase supplied with the kit [Promega]. Reactions were performed as follows: Reverse transcription: 42\u00b0C x 45 min \u2192 30 . A standard curve between the cycle threshold [CT] and concentrations of purified CC was prepared separately. The Corresponding CT values were obtained for both the non colitis control and the colitis RNA samples. The level of NHE-2 mRNA was calculated using the CT curve. A change in the mRNA was calculated with respect to the control CT values.www.ncbi.nlm.nih.gov) with the published sequence.The gel-purified PCR fragment was sequenced using a non-radioactive DNA sequencing method [Perkin-Elmer], with the downstream primer using a standard capillary gel electrophoresis method  in the RCF, Health Sciences Center, Kuwait University, Kuwait. Nucleotide sequence was identified using the Blast program  in the steady state level of NHE-2 protein in the crude lysates from inflamed colon as compared to non-colitis controls Figs . On the Since the western blot analysis has multiple variables, it was necessary to support this data with confocal microscopy. The confocal data as shown in The quality and yield [\u03bcg/mg tissue] of total RNA were consistent in both the control (C) and colitis (T) samples . The NHEThe level of NHE-2 mRNA measured using the end-point RT-PCR  in inflaThe level of HnRNA was also significantly decreased in inflamed colon . This dein vitro did not show any difference in the expression of NHE-2 protein levels as compared to untreated controls [data not shown].TNF-\u03b1 has been shown to suppress NHE-2 expression in the epithelial cell line through interaction with NFkB region present in the NHE-2 promoter region . In our + and Ca+2 play an important role in maintaining these functions. Sodium is transported through multiple mechanisms including Na-H exchanger which is located in the plasma membrane and in the inner compartment of eukaryotic cells  and known concentrations of the competitive control was constructed to calculate the level of NHE-2 mRNA expression. Interestingly, the real time PCR findings also showed a similar reduction in the level of NHE-2 mRNA, suggesting that the decrease in NHE-2 protein levels is due to a decrease in the NHE-2 mRNA abundance in inflamed tissue. Furthermore, the yield and the integrity of total RNA used in this study were not different in the inflamed colon than the controls . TherefoTo investigate if transcription has a role in regulating the level of mRNA in inflamed tissue, we measured the level of heteronuclear RNA using the real time RT-PCR with SYBR green. For this purpose we used an upstream primer (PR4) selected from an intron, and a downstream primer (PR5) selected from an adjoining exon of NHE-2 gene sequence . We usedin vitro. Since the level of these inflammatory mediators are induced in IBD [ex vivo findings discount a role of TNF-\u03b1 in the suppression of NHE-2 in the experimental colitis (data not shown). Our findings are different than those reported earlier [in vivo for the action of TNF-\u03b1 as compared to the present ex vivo study. In addition, recombinant cells are different in many respects including that they carried a recombinant NHE-2 gene promoter [ex vivo condition used in the present study. It is worth noting that TNF-\u03b1 is commonly used to treat Crohn\u2019s disease, and in this present model TNF-\u03b1 and other cytokines have been shown to be upregulated [Studies using recombinant cells have shown that NHE-2 gene is immune responsive as it responds to TNF-\u03b1 and INF\u03b3 d in IBD , 20, we d in IBD , 28\u201330.  earlier  which copromoter  which waegulated \u201319.In conclusion, taken together these findings suggest that NHE-2 is colocalized with NHE-3 on the apical domain of the colonic epithelial cells, and that NHE-2 is more abundant than the NHE-3 in the colonic epithelial cells. The decrease in NHE-2 expression together with NHE-3 and NHE-8 , 31\u201335 m"}
{"text": "N=196). The results indicated that there were no statistically significant differences between the intervention and control groups on change in HRQOL, but the final regression models were statistically significant. SF-36 mental component summary (MCS) score at baseline, stress at baseline, and change in stress were significant predictors for predicting change in the SF-36 MCS. SF-36 physical component summary (PCS) at baseline and change in stress were significant predictors for predicting change in the SF-36 PCS. The findings suggest that the development of an effective intervention in improving HRQOL should be considered within individual, interpersonal, societal, and cultural factors for future research and clinical practice.The purpose of this study was to examine the effect of a six-month lifestyle-based intervention on health-related quality of life (HRQOL) in older adults with hypertension. A secondary analysis of a randomized controlled trial was conducted to test the differences between the intervention and control groups on HRQOL ( The older population is growing significantly in the United States and global society. In 2014, the number of Americans aged 65 and above was 46 million, representing 15% of the total U.S. population; by 2030, the older population is estimated to be about 21% of the total population and one in 13 will be older than 85 [The World Health Organization (WHO) has emphasized the importance of assessing and promoting people's quality of life . One of Studies suggested that stress and social support may impact HRQOL in older adults \u201316. FriaThe conceptual framework guiding the current study was derived from the Social Cognitive Theory  and liteThe purpose of this study was to test the effects of a 6-month lifestyle-based intervention on HRQOL in older American adults with hypertension, accounting for stress and social support as mediating variables. After receiving a 6-month lifestyle-based intervention, the intervention group was hypothesized to significantly improve in person (stress) and environment  (H1) and outcome (HRQOL) (H2) in older adults with hypertension from pretest (baseline) to posttest (6 months) compared to the control group.This study was approved by the Institutional Review Board (IRB) of the University of North Carolina at Greensboro (study#: 14-0428). The sample in the current study was drawn from the Well Elderly 2 Study. The data from the Well Elderly 2 Study were provided by the Inter-university Consortium for Political and Social Research , 31. BriIn the present secondary analysis, we used only data collected during the first 6 months of the study (baseline and the first 6-month time point). Participants who self-reported taking blood pressure medication at baseline in the Well Elderly 2 Study were selected as subjects.Demographic characteristics and medical history obtained by participants' self-report included gender, age, race, educational level, prescription medications, over-the-counter medicine, and diagnosis.Stress was measured using the adapted Perceived Stress Scale . The PerSocial support was assessed using the Lubben Social Network Scale (LSNS) . The LSNHRQOL was measured using the 36-Item Short-Form Health Survey  , 39. TheH1 and H2, multiple linear regression using a hierarchical regression model building approach was performed to test the effect of the intervention and make predictions on criterion variables [p value\u2009<\u20090.05 was considered statistically significant. All analyses were performed using SPSS version 23 .Descriptive statistics were initially calculated using means and standard deviations or frequencies and percentages. Continuous variables were checked for outliers and normality in univariate analysis. To test hypotheses ariables , 44. Demp \u2265 0.05).There were a total of 196 participants in this study. Of the 196 participants, 103 were randomly assigned to the intervention group and 93 to the control group. p \u2265 0.05).At baseline, the average stress score was 43.7\u2009\u00b1\u200910.7, and the average of social support score was 27.2\u2009\u00b1\u20099.1. The mean scores of the SF-36 mental component summary (MCS) and physical component summary (PCS) were 46.7\u2009\u00b1\u200911.4 and 39.6\u2009\u00b1\u200910.1, respectively. As shown in p < 0.001). In the final hierarchical regression model, demographic variables , stress at baseline, and intervention versus control significantly accounted for 25% of the variance in change in stress (R2=0.25). In addition, stress at baseline accounted for a significant amount of variance in change in stress after controlling for the effect of demographic variables based on the second step of the hierarchical model building . Four years of college or more, Hispanic/Latino versus White Americans, and stress at baseline were significant predictors. Adjusting for all other factors, participants who received four years of college or more education were associated with a 0.22 increase in standard deviation (SD) units of predicted change in stress compared to participants who received less than high school; Hispanic/Latino participants were associated with a 0.20 increase in SD units of predicted change in stress compared to White participants. For every 1 SD increase in stress at baseline, the predicted mean decrease in change in stress was 0.49 SD units, adjusting for all other factors.p < 0.01). In the final hierarchical regression model, demographic variables, social support at baseline, and intervention versus control significantly accounted for 18% of the variance in change in social support (R2=0.18). Additionally, social support at baseline accounted for a significant amount of variance in change in social support, after controlling for the effect of demographic variables . The only significant predictor was social support at baseline, where for every 1 SD increase in social support at baseline, the predicted mean decrease in change in social support was 0.37 SD units, adjusting for all other factors.p < 0.001). In the final hierarchical regression model, demographic variables, SF-36 MCS score at baseline, intervention versus control, stress at baseline, change in stress, social support at baseline, and change in social support significantly accounted for 39% of variance in change in the SF-36 MCS (R2=0.39). The SF-36 MCS at baseline accounted for a significant amount of variance in change in the SF-36 MCS, after controlling for the effect of demographic variables in the second step of modeling . In the last step, stress at baseline, change in stress, social support at baseline, and change in social support accounted for a significant amount of variance in change in the SF-36 MCS after controlling for the effect of demographic variables, SF-36 MCS score at baseline, and the effect of intervention . The SF-36 MCS score at baseline, stress at baseline, and change in stress were significant predictors in the final model. For every 1 SD increase in the SF-36 MCS at baseline, the predicted mean decrease in the change in the SF-36 MCS was 0.66 SD units; for every 1 SD increase in stress at baseline, the predicted mean decrease in change in the SF-36 MCS was 0.27 SD units; for every 1 SD increase in change in stress, the predicted mean decrease in change in the SF-36 MCS was 0.28 SD units, adjusting for all other factors.p < 0.05). In the final hierarchical regression model, demographic variables, SF-36 PCS score at baseline, intervention versus control, stress at baseline, change in stress, social support at baseline, and change in social support significantly accounted for 18% of the variance in change in the SF-36 PCS (R2=0.18). The SF-36 PCS score at baseline accounted for a significant amount of variance in the change in the SF-36 PCS after controlling for the effect of demographic variables . The SF-36 PCS at baseline and change in stress were significant predictors of change in PCS scores in the final model. For every 1 SD increase in the SF-36 PCS at baseline, the predicted mean decrease in the change in the SF-36 PCS was 0.38 SD units; for every 1 SD increase in change in stress, the predicted mean decrease in change in the SF-36 PCS was 0.18 SD units, adjusting for all other factors.This secondary analysis examined the effectiveness of a lifestyle-based intervention on HRQOL in older adults with hypertension and investigated stress and social support as mediating variables. As many older adults suffer from hypertension, developing effective interventions to enhance older adults' HRQOL is necessary for healthy aging. The results of this analysis provide empirical evidence, advance the scientific knowledge, and propose intervention recommendations for future research and clinical practice in older adults with hypertension.The findings of the study indicated that there were no statistically significant intervention effects on stress, social support, and HRQOL, but the final regression models were statistically significant in the last step of the hierarchical multiple regression analysis. According to Baron and Kenny (1986) criteria for a mediation analysis, social support and stress failed to function as mediators in the current study . This reIn this study, stress at baseline and change in stress were significant predictors in predicting the mental component of HRQOL; change in stress was a significant predictor in predicting the physical component of HRQOL. Gerber also found that higher perceived stress was significantly associated with poorer mental HRQOL in older adults . In addiAging is a multifaceted process and is related to reduced functional capacity and chronic diseases \u201349. ManyThe current study has several limitations. First, the effect of the lifestyle-based intervention was tested from pretest (baseline) to posttest (the 6-month time point). Hence, the lifestyle intervention may not have significant short-term effects on change in social support, stress, and HRQOL , 50, 51.There is limited research to test the effects of lifestyle interventions on HRQOL in older adults with hypertension. In this study, the results revealed that the regression model is statistically significant in predicting changes in HRQOL according to lifestyle-based intervention, stress, and social support. Educational levels, race, stress at baseline are significant predictors for predicting change in stress; social support at baseline is the significant predictor for predicting change in social support. In addition, SF-36 MCS score at baseline, stress at baseline, and change in stress are significant predictors of change in MCS scores in the final model. SF-36 PCS score at baseline and change in stress are significant predictors for predicting change in the SF-36 PCS. As many older adults have high blood pressure and reduced HRQOL, developing effective interventions in promoting hypertension self-management and improving HRQOL for older adults with hypertension is essential. This secondary analysis suggests that stress management and social support resources should be included in the lifestyle intervention for future research and clinical practice. The results indicate that the development of an effective intervention in improving HRQOL should be considered within individual, interpersonal, societal, and cultural factors when implementing the lifestyle-based interventions."}
{"text": "The United States Food and Drug Administration (FDA) reviews class III orthopedic devices submitted for premarket approval with pivotal clinical trials. The purpose of this study was to determine the types of orthopedic devices reviewed, the design of their pivotal clinical trials, and the subjective factors affecting the interpretation of clinical trial data.Meetings of the FDA Orthopaedic and Rehabilitation Devices Panel were identified from 2000\u20132016. Meeting materials were collected from FDA electronic archives and notes were made regarding the device-type and subsequent approval and recall, the design of pivotal clinical trials, and issues of trial interpretation debated during panel deliberations.The panel was convened on 29 separate occasions over the course of 35 days to deliberate 38 distinct topics. Of these, 23 topics included clinical data submitted for approval of a device, and two topics were excluded. Of the 23 devices, five were biologic, three were hip arthroplasty, three were disc arthroplasty, two were viscosupplementation, three were interspinous process devices, and seven were other devices. Of the 23 pivotal trials, 20 (87.0%) were randomized controlled trials (RCTs), consisting of 13 (65.0%) non-inferiority trials and 7 (35.0%) superiority trials, and all RCTs were two-arm trials. At panel, the most commonly debated issues were related to the design and interpretation of non-inferiority trials.A broad array of device types is reviewed by the FDA. The predominance of two-arm non-inferiority trials as pivotal studies indicates that the nuances of their design and interpretation are commercially important. Orthopedic surgery is one of the largest segments of the medical device industry. In the United States jurisdiction, orthopedic devices are regulated by the Division of Orthopedic Devices, Office of Device Evaluation, Center for Devices and Radiologic Health of the Food and Drug Administration (FDA). With few exceptions, many of the most complex, novel, or high-risk orthopedic devices (class III devices) are subject to premarket approval (PMA), the FDA\u2019s most intensive review process for devices . TypicalThe FDA utilizes approximately 50 committees and panels that provide expert advice on matters of science and policy. Of these, the Orthopaedic and Rehabilitation Devices Panel provides advice on orthopedic devices, and PMA applications may be subject to review in a public forum. Though not all PMAs come before the panel , the PMA process including panel review represents the most intensive scrutiny and highest level of scientific deliberation that an orthopedic device may receive in consideration of regulatory approval.The purpose of the present study was to assess the design of pivotal trials of orthopedic devices and their interpretation at FDA panel meetings. This is important because IDE trials are frequently the best scientific evidence available for both regulatory affairs and clinical decision making. The relationship of device characteristics to the rate of device approval and recall was studied, since these are mechanismfigurs by which devices enter and exit the market for routine clinical use. Similarly, the characteristics of the IDE trials were reviewed including the trial designs and their relationship to approval and recall. Finally, those clinically relevant aspects of trial structure that affect panel deliberations were identified.Meetings of the Orthopaedic and Rehabilitation Devices Panel were identified from the beginning of the 2000 calendar year to 2016 from official announcements in the Federal Register. Meeting materials were obtained from the FDA electronic archives, including panel-packs, sponsor executive summaries, FDA executive summaries, rosters, postmeeting summaries, and official meeting transcripts. Notes were made regarding the purpose of the meeting as either reclassification, special advisory, PMA, or premarket notification ).For PMA and 510(k) topics, IDE trials were classified as a randomized clinical trial (RCT) versus observational/nonrandomized study, and superiority versus non-inferiority design. The number of arms and the type of control were recorded. Notes were made regarding comments and questions of panelists regarding complexities in the interpretation of clinical trial data, as reflected in the official transcripts when available. Comments were qualitatively categorized into three major categories: outcome measures, randomized trial conduct, and issues specific to non-inferiority trials. Among outcome measures, subtopics included time points, primary composite endpoint, secondary endpoints, surrogate radiographic endpoints, choice of clinical instruments, and time of final follow-up. For randomized trials, subtopics included power, randomization ratio, blinding, number of arms, choice of control procedure, and rate of crossover, dropout, and missing data. For issues specific to non-inferiority trials, subtopics included the choice of active control, the choice of non-inferiority margin, assay sensitivity, and analysis of datasubsets , modified ITT, as-treated (AT), and per-protocol (PP) analyses).For each device, a note was made of the device type\u2014biologic, hip arthroplasty, disc arthroplasty, viscosupplementation, interspinous process device, or other device . The subsequent approval and recall of devices was noted up to the time of writing. The date of each conducted panel meeting was noted. For the purposes of hypothesis testing, the number of meetings per year was analyzed by dividing the investigation period (2000\u20132016) into two roughly comparable portions\u2014years 2000\u20132008 and 2008\u20132016 inclusive. The rate of device approval was tested with the rate-ratio test for the intensity of Poisson processes. The subsequent approval and recall of devices was investigated up to the time of writing. For the purposes of hypothesis testing, devices were grouped in four dichotomous ways: spinal versus nonspinal, arthroplasty versus nonarthroplasty, biologic versus nonbiologic, and other devices versus non-other. Hypotheses were tested with the Fisher exact test.Between 20 July 2000 and 20 April 2016, the panel was convened on 29 separate occasions over the course of 35 days to deliberate 38 distinct topics. Table\u00a0Of the 23 unique devices with pivotal IDE trial data, 20 (87.0%) were RCTs, consisting of 13 (65.0%) non-inferiority trials and seven (35.0%) superiority trials. The remaining three (13.0%) studies were observational/non-randomized. All non-inferiority studies (13) were two-arm trials versus an active control, and none was a three-arm study including a sham control. Table\u00a0p\u2009>\u20090.05). The results do not change by excluding the middle year 2008 or by assigning it to the earlier or later period.In total, five devices were biologic, three were hip arthroplasty, three were disc arthroplasty, two were viscosupplementation, three were interspinous process devices, and seven were other devices. Figure\u00a0p\u2009>\u20090.05). Regarding device type, there was no significant difference in the rate of approval between spinal versus nonspinal devices (p\u2009=\u20090.66), biologic versus nonbiologic devices (p\u2009=\u20090.28), and other devices versus non-other devices (p\u2009=\u20090.35). The only factor affecting approval was whether the device was an arthroplasty device of any type (p\u2009=\u20090.047), though this is no longer significant after multitest correction.Of 23 devices, the approval status was known for 21 as of the time of writing, as approval decisions and their disclosure takes time from the date of the panel meeting. Of these 21 devices, fourteen devices were approved subsequent to panel review (66.7%), and no device directly reviewed by the panel was subsequently recalled. The clinical trial type of superiority versus non-inferiority was not significantly associated with approval  premarket notification . SubsequRegarding device approval, approximately two-thirds of devices were approved at the time of writing. Arthroplasty devices had the highest rate of approval, and biologic devices had the lowest rate of approval. The only device-related factor associated with approval was whether the device was for arthroplasty; however, this classification represented a diverse group of devices from hip to cervical spine arthroplasty. Of note, it also included a number of hard-on-hard bearing surfaces for hip arthroplasty. Metal-on-metal bearing surfaces have become controversial, and were the subject of a special FDA advisory panel during the study period . DespiteA broad range of devices is reviewed by the FDA\u2019s Orthopaedic Devices Panel. Although few device or trial-related factors affect approval or recall, panel review is associated with no recent recalls. The majority of devices are studied in pivotal two-arm non-inferiority trials which are subject to complex technical issues and nuances in their interpretation."}
{"text": "All six World Health Organization (WHO) regions have established measles elimination goals, and three regions have a rubella elimination goal. Each region has established a regional verification commission to monitor progress toward measles elimination, rubella elimination, or both, and to provide verification of eliminationCountries report data from measles and rubella cases identified through laboratory-supported case-based surveillance systems to WHO. Laboratory testing includes both serologic and molecular confirmation of suspected cases and genetic characterization of viruses from confirmed cases. Participating GMRLN laboratories report MeV and RuV sequence dataAccording to the monthly reports of 184 countries that reported measles and rubella case-based surveillance data in 2018, a total of 317,445 serum specimens were received by the participating GMRLN laboratories from patients with suspected cases, an increase of 101% compared with the number of specimens received in 2016. Among 275,020 (87%) specimens tested for measles immunoglobulin M, 78,950 (29%) were positive; 203,898 (64%) also were tested for rubella immunoglobulin M, and 11,874 (6%) were positive. By the end of 2018, MeaNS contained 47,521 MeV sequences, a 93% increase from the 24,571 sequences reported as of July 1, 2015 . Among the 10 most commonly reported named strains, two appeared in all six regions .During 2016\u20132018, five of the 13 recognized RuV genotypes were detected, and the number of detected RuV genotypes decreased from five in 2016 (58% of the sequences belonged to genotype 1E and 40% to genotype 2B) to two (1E and 2B) in 2018 . HoweverGMRLN continues to provide high-quality laboratory support to surveillance for measles and rubella virus transmission and critical evidence needed for the verification of elimination. The increase in serologic testing and the number of sequences reported to the databases reflect an expansion of the capacity of GMRLN as well as the resurgence of measles in many countries during 2018. With support of the molecular surveillance data provided by GMRLN, measles elimination has been verified by 81 (42%) of the 194 WHO member countries and rubella by 76 (39%) of the 194 countries.The MeaNS database recognizes distinct N450 sequences and assigns DSIds to enable the identification of related MeVs in different countries and regions. In addition, a convention of naming the MeV strains with the same DSId is used. However, when defining endemic circulation of a specific MeV strain, caution should be exercised in interpreting the significance of MeV N450 sequences with different DSIds, named strains, or both. Given the conserved nature of the MeV genome, even within the highly variable N450 coding region, identical N450 sequences can be detected over multiple years and thus might not be linked or in the same direct line of transmission within a country or region. Conversely, sequences with a single nucleotide difference within an identified short chain of MeV transmission will be given different DSIds, with different names, even though they might be epidemiologically linked.The current naming convention does not describe MeV lineages derived from sequence analysis of regions of the MeV genome other than N450. To further differentiate viral transmission chains, additional sequence information from other regions of the genome is needed. Using an expanded sequence window in addition to the N450 sequence has been proposed for countries and regions where measles has been eliminated or is nearing elimination  accounted for 95% of reported sequences. Of 13 rubella virus genotypes, reported genotypes declined from five to two.Diversity of measles and rubella viruses has decreased globally, consistent with progress toward elimination. Continued collection of specimens from all confirmed cases for genotyping and submission of wild-type virus sequences to global databases will strengthen case-based surveillance."}
{"text": "A new family of fluorescent thiophene and thienothiophene-containing squaraine dyes is described with tunable wavelengths that cover the absorption/emission range of 600\u2013800 nm. The deep-red and near-infrared fluorescent compounds were easily prepared by simple synthesis and purification methods. Spectral studies showed that each squaraine was rapidly encapsulated by a tetralactam macrocycle, with nanomolar affinity in water, to produce a threaded supramolecular complex with high chemical stability, increased fluorescence quantum yield, and decreased fluorescence quenching upon dye self-aggregation. Energy transfer within the supramolecular complex permitted multiplex emission. That is, two separate dyes with fluorescence emission bands that match the popular Cy5 and Cy7 channels, could be simultaneously excited with a beam of 375 nm light. A broad range of practical applications is envisioned in healthcare diagnostics, microscopy, molecular imaging, and fluorescence-guided surgery. Organic dyes that emit fluorescence in the near infrared (NIR) window 650\u2013900 nm) are needed for biological imaging as this wavelength region has relatively deep tissue penetration, minimal tissue auto fluorescence, and lower Rayleigh scattering of the light ,2,3. At 0\u2013900 nm Squaraine dyes are a well-known family of NIR fluorescent dyes with intense and narrow absorption bands, high fluorescence quantum yields, and excellent photostabilities . BecauseS1\u2013S3) that were easily prepared from commercially available materials in a few steps, and water-soluble analogues (S1PEG\u2013S3PEG) that were obtained by appending long polyethylene glycol (PEG) chains. We find that the dyes form supramolecular complexes with the tetralactam macrocycles M1 or M2 to produce a suite of 12 fluorescent compounds that span the absorption window of 600\u2013800 nm, making them a very attractive set of dyes for a wide range of future biological imaging applications.We decided to develop a new set of squaraine chromophores with incrementally extended absorption/emission wavelengths. We knew that squaraine structures containing aminophenyl or aminothiophene units would be useful for operation in the region of 600\u2013700 nm . The reaS1 and S2, were synthesized by similar procedures using N,N-dibenzylaminophenyl semisquaraine 2 as a common building block  at one or both ends of the central chromophore, which ensures that macrocycle threading is facile   1 thiophene (4): Thienothiophene  was dissolved in acetic acid (10 mL). N-bromosuccinimide  was added and the reaction mixture was stirred at room temperature for 2 h. Solvent was removed and the residue was dissolved in diethyl ether (80 mL) and washed with NaOH , H2O (100 mL \u00d7 3) and brine (100 mL). The resulting solution was dried over Na2SO4, and the solvent was removed by rotary evaporation to obtain pure 4 as a light yellow liquid . 1H-NMR  \u03b4 7.40 , 7.28 , 7.20\u20137.14 . 13C-NMR  \u03b4 127.57, 126.78, 122.32, 121.98, 119.60, 119.24. HRMS-ESI m/z 217.8837 .2-amino)ethan-1-ol (5): Compound 4 , Cu0 , CuI  and K3PO4\u00b7H2O  were suspended in 2-(methylamino)ethanol (15 mL). The reaction mixture was stirred at 90 \u00b0C over 5 h. After cooling to room temperature, H2O (80 mL) was added, and the reaction mixture was extracted with diethyl ether (100 mL \u00d7 3). The organic phase was combined and dried over Na2SO4, the solvent was removed and the residue was purified by column chromatography  using 10\u201340% EtOAc/hexane to obtain pure 5 as a light yellow solid . 1H-NMR  \u03b4 7.10 , 7.07 , 6.12 , 3.99 , 3.80 , 3.40 , 3.00 . 13C-NMR  \u03b4 206.11, 160.53, 139.67, 120.16, 119.69, 93.96, 59.29, 57.85, 40.43, 29.67, 29.51, 29.36, 29.21, 29.05. HRMS-ESI m/z 214.0379 .N-methyl-N-(2-(prop-2-yn-1-yloxy)ethyl)thienothiophen-2-amine (6): Propargyl bromide  was added to a mixture of compound 5 , aqueous NaOH  and toluene (15 mL). TBA HSO4 (200 mg) was added to the mixture as a phase transfer reagent and the resulting solution was stirred at room temperature for 5 h. Toluene was removed by rotary evaporation and H2O (100 mL) was added to the residue. The resulting solution was extracted with diethyl ether (100 mL \u00d7 3). The organic phase was combined and dried over Na2SO4, the solvent was removed and the residue was purified by column chromatography  using 5\u201320% EtOAc/hexane to obtain pure 6 as a yellow liquid . 1H-NMR  \u03b4 7.11 , 7.09 , 6.16 , 4.18 , 3.75 , 3.49 , 3.00 , 2.93 . 13C-NMR  \u03b4 205.53, 160.12, 139.58, 125.88, 120.28, 119.63, 94.26, 80.10, 75.36, 67.20, 58.03, 54.88, 40.36. HRMS-ESI m/z 252.0540 .S2: Compound 6  and 3-(4-(dibenzylamino)phenyl)-4-hydroxycyclobut-3-ene-1,2-dione  were dissolved in a mixture of 1-butanol (15 mL) and benzene (45 mL). The reaction was heated to reflux with Dean-Stark distillation for 2 h. After cooling to room temperature, the solvent was removed and the residue was purified by column chromatography using 0\u20137% MeOH/CHCl3 to obtain pure S2 as green solid . 1H-NMR  \u03b4 8.28\u20138.14 , 7.39\u20137.27 , 7.25\u20137.13 , 6.85 , 6.23 , 4.77 , 4.17 , 3.81 , 3.67 , 3.25 , 2.44 . 13C-NMR: Limited compound solubility prevented 13C analysis. HRMS-ESI m/z 602.1704 .S2PEG: Compound S2 , azido-mPEG453 , triethylamine (2 drops) and TBTACu(I)Br (2 mg) was dissolved in CHCl3 (5 mL) and the reaction mixture was stirred at room temperature for 12 h. After removing the solvent, the residue was purified by column chromatography (silica gel as stationary phase) using 0\u201310% MeOH/CHCl3 to obtain the crude product. The crude product was further purified by a second column  using 0\u20135% MeOH/CHCl3 to obtain pure S2PEG as green solid . 1H-NMR  \u03b4 8.23\u20138.20 , 7.69 , 7.35 , 7.29 , 7.23\u20137.18 , 6.84 , 6.23 , 4.76 , 4.64 , 4.54\u20134.46 , 3.84\u20133.71 , 3.70\u20133.48 , 3.37 , 3.20 . MS-MALDI (DHBA as matrix) showed a set of peaks around 2421, which reflected the polydispersity of the PEG45 chains.2-amino)ethan-1-ol (7): Compound 4 , Cu0 , CuI  and K3PO4\u00b7H2O  was suspended in 2-(ethylamino)ethanol (15 mL). The reaction mixture was stirred at 90 \u00b0C over 5 h. After cooling to room temperature, H2O (80 mL) was added, and the reaction mixture was extracted with diethyl ether (100 mL \u00d7 3). The organic phase was combined and dried over Na2SO4, the solvent was removed and the residue was purified by column chromatography  using 10\u201340% EtOAc/hexane to obtain pure 7 as light yellow solid . 1H-NMR  \u03b4 7.10 , 7.07 , 6.17 , 3.97\u20133.81 , 3.76 , 3.45\u20133.35 , 1.19 . 13C-NMR  \u03b4 205.64, 159.34, 139.55, 120.06, 119.63, 94.31, 59.32, 55.29, 48.45, 29.53, 29.38, 29.22, 29.07, 28.92, 11.67. HRMS-ESI m/z 228.0534 .N-ethyl-N-(2-(prop-2-yn-1-yloxy)ethyl)thienothiophen-2-amine (8): Propargyl bromide  was added to a mixture of compound 7  in toluene (15 mL) and NaOH solution . TBA HSO4 (200 mg) as phase transfer reagent was added to the mixture and the resulting solution was stirred at room temperature for 5 h. Toluene was removed by rotary evaporation and H2O (100 mL) was added to the residue. The resulting solution was extracted with diethyl ether (100 mL \u00d7 3). Organic phase was combined and dried over Na2SO4, the solvent was removed and the residue was purified by column chromatography  using 5\u201320% EtOAc/hexane to obtain pure 8 as a yellow liquid . 1H-NMR  \u03b4 7.11 , 7.08 , 6.18 , 4.18 , 3.72 , 3.48 , 3.39 , 2.93 , 1.19 . 13C-NMR  \u03b4 205.55, 159.01, 139.54, 125.67, 120.24, 119.65, 94.55, 80.14, 75.39, 67.45, 58.09, 52.51, 48.43, 29.42, 29.27, 29.12, 11.82. HRMS-ESI m/z 266.0685 .S3: Compound 8 , 3,4-dihydroxycyclobut-3-ene-1,2-dione  was dissolved in a mixture of 1-butanol (15 mL) and benzene (45 mL). The reaction was heated to reflux with Dean-Stark distillation for 2 h. After cooling to room temperature, the solvent was removed and the residue was purified by recrystallization in MeOH to obtain pure S3 as a brown solid . 1H-NMR  \u03b4 8.11 , 6.19 , 4.18 , 3.81 , 3.67 , 3.22 , 2.45 . 13C-NMR: Limited compound solubility prevented 13C analysis. HRMS-ESI m/z 608.0921 .S3PEG: Compound S3 , azido-mPEG453 , triethylamine (2 drops) and TBTACu(I)Br (2 mg) were mixed in CHCl3 (5 mL) and the reaction mixture was sonicated at 40 \u00b0C for 4 h. After removing the solvent, the residue was purified by column chromatography (silica gel as stationary phase) using 0\u201310% MeOH/CHCl3 to obtain the crude product. The crude product was further purified by a send column chromatography  using 0\u20135% MeOH/CHCl3 to obtain pure S3PEG as a brown solid . 1H-NMR  \u03b4 8.00 , 7.67 , 6.13 , 4.60 , 4.47 , 3.79 , 3.74 , 3.66\u20133.39 , 3.33 , 1.22 . MS-MALDI (DHBA as matrix) showed a set of peaks around 4391 which reflected the polydispersity of the PEG45 chains.Association Measurements: Stock solutions of squaraine guest, generally 0.03\u20133 \u00b5\u039c were prepared and stock solutions of the host (0.6\u201360 \u00b5M) were made by using the guest solution as the solvent (to keep the concentration of guest constant during the titration). A solution of guest (1 mL) was placed in the cuvette and host solution was titrated into guest solution. Spectra changes were recorded by fluorometer after each injection. Association constants were determined using Origin LabTM 8.6 software  that enabled non-linear least squares fitting of the titration data with an equation for 1:1 binding.Kinetic Measurements: Kinetic studies were performed by using a SFA-20M stopped flow device  . Equal volumes of host solution and guest solution were mixed by the stopped flow device. The spectral changes were monitored by fluorescence. Second order rates constants were determined using Origin LabTM 8.6 software that enabled non-linear least squares fitting of the titration data with an equation for second order kinetics.A new family of fluorescent thiophene and thienothiophene-containing squaraine dyes was prepared using simple synthesis and purification methods. Each squaraine can be rapidly encapsulated by a tetralactam macrocycle in organic or aqueous solution. The threaded supramolecular complexes have nanomolar affinity in water, increased stability towards chemical attack by nucleophiles, and favorable optical properties such as increased fluorescence quantum yield and decreased fluorescence quenching upon dye self-aggregation. Together, the set of squaraine dyes and their macrocycle complexes cover the absorption/emission range of 600\u2013800 nm. A notable favorable attribute with the threaded complexes is the capability to excite each of them with 375 nm light and produce an emission band that is characteristic of the encapsulated squaraine. A wide set of single wavelength and multiplex detection techniques are envisioned using these new dyes for various practical applications in diagnostics, microscopy, molecular imaging, and fluorescence-guided surgery."}
{"text": "Coxiella burnetii is a Gram negative bacterium that survives and grows in a large Coxiella replicative vacuole (CRV), which displays lysosomal and autophagic features. In this report, we present evidence that both, EPAC and its downstream effector Rap2b, were recruited to the CRV. The transient over-expression of the Rap2b wt protein, but not its inactive mutant Rap2b \u0394AAX, markedly inhibited the development of the large CRV. Additionally, Rap2b wtinhibited the fusion of early Coxiella phagosomes with the fully developed CRV, indicating that homotypic fusion events are altered in the presence of high levels of Rap2b wt. Likewise, the fusion of endosome/lysosomal compartments (heterotypic fusions) with the large CRV was also affected by the over-expression of this GTPase. Interestingly, cell overexpression of Rap2b wt markedly decreased the levels of the v-SNARE, Vamp7, suggesting that this down-regulation impairs the homotypic and heterotypic fusions events of the Coxiella vacuole.Cyclic Adenosine 3\u2032,5\u2032-monophosphate (cAMP) is a key second messenger known to directly regulate not only the protein kinase A (PKA) activity but also other important molecules such as the exchange protein activated by cAMP (EPAC), which is as a guanine nucleotide exchange factor (GEF) of the low molecular weight GTPase, Rap2.  Coxiella burnetii, the etiological agent of the Q-fever, is an obligate intracellular bacterium. This microorganism has a biphasic life cycle in which the small cell variant (SCV) and the large cell variant (LCV) alternate. The LCV form is generated in the lysosomal-like large replicative compartment  of infected cells, where the acidic microenvironment favors its replication . In . In Coxim (T4SS)  6]. The. TheCoxiynthesis . We haveynthesis . Furtherynthesis  9]..CoxiellaThe autophagy pathway is a highly conserved, physiological degradation process in eukaryotic cells. During autophagy, small portions of cytoplasm or damaged organelles are sequestered into double-membrane vesicles named autophagosomes. These vesicles then fuse with degradatives organelles which supply the hydrolytic enzymes for breaking down and eventual recycling of the sequestered material. The Microtubule-associated protein light chain 3 (LC3) has been shown to be an autophagosomal marker in mammals. There are two forms of LC3 called LC3-I and LC3-II, which are produced post-translationally in various cell types. LC3-I is a cytosolic protein, whereas LC3-II is membrane-bound and specifically associates with autophagosome membranes.Staphylococcus aureus and Legionella pneumophila, exploit the autophagy pathway for their own benefit in order to survive and replicate in the host cells.  [12 [1211] . Th. Th18]. S. aureus . Th. Th20]. . aureus . That st. aureus .C. burnetii co-opt to generate its replicative vacuole. The results obtained in this work offer a deeper insight into the molecular components of the host cell that are involved in the regulatory mechanism of the development of C. burnetii replicative vacuole.In this work, we aimed at studying the effectors EPAC and Rap2b as key regulators of CRV development. We have demonstrated that the cAMP modulated protein EPAC was recruited to the CRV. In addition by analyzing the EPAC downstream effector Rap2b, we determined that the latter factor, but not its inactive mutant Rap2b \u0394AAX, is also recruited to the CRV from early times p.i. More importantly, we demonstrated that over-expression of Rap2b wt protein, but not Rap2b \u0394AAX, significantly impaired the development of the large CRV. Interestingly, we have shown that the over-expression of Rap2b wt reduced both, the homotypic and the heterotypic fusion capacity of the CRV, and also, decreased the intracellular levels of the v-SNARE Vamp7. These results suggest that the over-expression of the active form of Rap2b affects molecular components of the fusion machinery that Coxiella antiserum and mCherry-Coxiella burnetii were generously provided by Dr. Robert Heinzen . Coxiella-GFP (Tn1832) and the DotA mutant GFP (Tn292) were kindly provided by Dr. Matteo Bonazzi . Texas Red-tagged dextran (3 kDa) was purchased from Molecular Probes. PEGFP-Rap2b wt and pEGFP-Rap2b \u0394AAX plasmids were kindly provided by Dr. MauroTorti . Plasmids for EPAC-GFP, \u0394(1\u2013148)-EPAC-GFP, \u0394(72\u2013148)-EPAC-GFP were kindly provided by Dr. Xiaodong Cheng .D-MEM and alpha-MEM were obtained from Gibco Laboratories ; fetal bovine serum (FBS) was obtained from GIBCO BRL/Life Technologies . The anti-Rap2b antibody and Rap2b siRNA were purchased from Santa Cruz Biotechnology . Rabbit anti-2 atmosphere until 80% confluence was reached.Vero cells , HeLa cells  and Chinese hamster ovary cells (CHO)  were grown in 24-well plates in either D-MEM or \u03b1-MEM, supplemented with 15% FBS, and the antibiotics streptomycin (50\u03bcg/ml) and penicillin (50 \u03bcg/ml), at 37\u00baC in a 5% COCHO cells were transfected with the plasmids (1 \u03bcg/\u03bcl) using the Lipofectamine 2000 reagent  as previously described in . TransfeC. burnetii clone 4, phase II, Nine Mile strain was performed as previously described , . Th. ThS. auC. burnetii (homotypic fusion) or vesicles from the endocytic, autophagic and secretory pathways (heterotypic fusion). As demonstrated before, an inhibition of fusion causes a decrease in the size of the CRVs and therefore increases the number of smaller vesicles containing C. burnetii 35].[35].34][.[35].34] pathway . The mulC. burnetii was not able to fuse with lysosomes or with other CRV in the absence of Vamp7 . We . We 38].of Vamp7 . Since CCoxiella vacuole and that this effect might be at least in part, by modulating the levels of Vamp7. This is a very intriguing observation. However, further studies would be necessary to determine the critical molecular mechanisms involved in this modulation.In conclusion, in this report we have demonstrated that the cAMP effectors EPAC and Rap2b are key regulators of CRV development. We have proved that the small GTPase Rap2b has a critical role in the development of CRV by altering the fusion events of the S1 Table(PDF)Click here for additional data file."}
{"text": "Pre-exposure prophylaxis (PrEP) targeting high-risk men who have sex with men (MSM) has been shown to be a cost-effective HIV control measure. However, the approach could be a challenge in low HIV incidence places with a low proportion of high-risk MSM. To examine the impact of PrEP in such setting in Asia, we developed an epidemic model and conducted cost-effectiveness analysis using empirical multicentre clinical and HIV sequence data from HIV-infected MSM in Hong Kong, in conjunction with behavioural data of local MSM. Without PrEP, the HIV incidence (per 100 person-years) would increase from 1.1 to 1.6 between 2011 and 2021. PrEP could avert 3\u201363% of total new infections in a five-year period (2017\u20132021), the variability of which depends on the implementation strategies and combination with test-and-treat. However, under current market drug price in 2016, the incremental cost per quality-adjusted life-year gained (QALYG) of PrEP (USD1583136/QALYG) is almost 3 times higher than test-and-treat intervention alone (USD396874/QALYG). Assuming 93% fall of PrEP drug price and in combination with test-and-treat, putting 30% of MSM on non-targeting PrEP would be more feasible, cost-effective (USD268915/QALYG), and could avert more new infections (40%). PrEP could contribute to HIV epidemic control in a low incidence place. In Australia, the proportion of HIV-infected MSM receiving treatment increased from 84% in 2014 to 88% in 2016, and the number of new diagnoses decreased by 8% per year1. In UK, the number of new diagnoses among MSM declined by 1% from 2014 to 2015, and the treatment coverage was 95% in 20152. Besides treatment-as-prevention (TasP), the epidemic could further be controlled through addressing prevention needs of HIV negative individuals. The effectiveness of pre-exposure prophylaxis (PrEP), a biomedical preventive measure, was demonstrated in a number of studies, the results of which had been comprehensively reviewed3. In 2012, PrEP was approved by Food and Drug Administration (FDA). PrEP offers new opportunities to protecting HIV uninfected individuals including MSM, the HIV prevalence of which is often higher compared to other community groups in places like Europe and Asia Pacific5. PrEP as a preventive measure has been shown in modelling studies to avert a proportion of new infections and determined to be cost-effective in the estimations9. In a sub-study of iPrEX, a 99% transmission risk reduction was estimated under full adherence to PrEP usage10. The major challenge is to identify the most effective means for implementation.Despite a relatively high antiretroviral treatment (ART) coverage of over 80% in men who have sex with men (MSM) diagnosed with HIV infection since 2015, the annual number of new diagnoses has not fallen by more than 20%, as shown in some places like Australia and the United Kingdom (UK)11. In low HIV incidence setting, introduction of PrEP has been shown in modelling studies (without consideration of cost) to contribute to epidemic control, as reported in Australia6, rural Zambia7, UK12, and Canada13. Some of these modelling studies and a cost-effectiveness analysis study in the Netherlands concluded with the recommendation of prioritizing high-risk groups in low incidence locality for PrEP14. Naturally, with the small proportion of high-risk MSM in these places, the cost of identifying and managing hidden population at high-risk of infection could be very high, while the actual proportion of MSM subsequently put on PrEP would be even smaller. In addition, stigma might be introduced by the targeting approach adopted for PrEP. High-risk MSM might be discouraged to take PrEP, while the programme cannot stop low-risk MSM from taking PrEP if they self-claim to be at high risk of HIV infection. Such phenomena could constitute new challenges to PrEP implementations.In 2014, World Health Organization (WHO) recommended prioritizing populations at substantial risk of HIV infection when offering PrEP. WHO defined substantial risk based on local sub-population epidemiology (HIV incidence \u22653 per 100 person-years) in conjunction with personal assessment17. Hong Kong, an Asian city, has a relatively stable HIV epidemic after an initial expansion phase predominantly affecting MSM, while the rate of infection in heterosexuals has remained low. The situation is different from India and South Korea, where heterosexual transmission continued to predominate. As of 2015, the cumulative number of reported HIV infected MSM cases was 3151  in Hong Kong18. Among MSM, the HIV prevalence is around 5%, and the annual number of new diagnoses had increased from 170 in 2010 to 464 in 201518, despite the low incidence density of 1.1 per 100 person-year (http://www.chp.gov.hk/files/pdf/interim_statement_on_hiv_pre_exposure_prophylaxis.pdf). The rates of linkage to and retention in care, treatment initiation and viral load suppression are high . In such setting, it is a challenge to effectively achieve further control of the HIV epidemic in MSM, and PrEP offers a new opportunity.We hypothesize that the additional benefit of targeting high-risk MSM in low incidence places for PrEP could be very small. To prove the hypothesis, epidemic modelling parameterized by clinical, HIV-1 sequences and behavioural data is a useful approach that has been applied in previous studies. To date, numerous PrEP modelling studies for MSM have been conducted in the United States, Canada, Europe, South America, Africa, and Australia, but only a few were reported in Asian countries (India and South Korea)2, https://www.bycensus2016.gov.hk/en/bc-mt.html). A previous study has estimated that 4.1% of adult male in Hong Kong were MSM, and 47.1% of them were sexually active19. The estimated number of sexually active MSM was around 50,000 in 2017. Apart from a pilot study, PrEP is currently not available as a public health preventive service in Hong Kong, and the cost of self-financed PrEP is very high (~USD23 per dose in 2016) in the absence of programmatic support. While some degree of PrEP awareness has been shown (26.6%), the current number of MSM on PrEP is speculatively small (1%)20.Hong Kong is a metropolitan city, with a highly mobile population  and high population density  Ordinance. Individual consent was waived. The datasets used in the current study are not publicly available because the data are owned separately by third parties. Access to these data and permission could be inquired through Department of Health, Hong Kong Special Administrative Region Government, Queen Elizabeth Hospital and Princess Margaret Hospital.There are three HIV specialist clinics providing treatment to HIV-infected patients in the public service in Hong Kong. Clinical data (baseline and follow-up records) in 1985\u20132014, and HIV-1 genotype resistance testing (GRT) sequences in 1994\u20132012 of HIV-infected adult MSM were collected from all three clinics for model parameterization. The collected data accounted for 96% (1886/1958) of the cumulative reported HIV MSM cases by 2012. Results of our behavioural study on MSM were used to set behavioural parameter values22. Collected sequences  were aligned by MUSCLE in MEGA6. From the constructed neighbour-joining tree, clusters were identified . They were further classified into subgroups by size of the clusters (number of cases) and by HIV subtype. Each subgroup was represented by one sub-model, and each sub-model included high and low-risk MSM for both HIV negative and positive MSM. A MSM is classified as belonging to the low-risk category if he has lower partner exchange rate , or high-risk if there has been higher partner exchange rate  high-risk and low-risk susceptible MSM, (b) undiagnosed non-locally acquired infections, (c) undiagnosed individuals in acute infection, chronic infection categorized by CD4 levels of \u2264200/\u03bcL, 201\u2013350/\u03bcL, 351\u2013500/\u03bcL, >500/\u03bcL, and AIDS, (d) diagnosed individuals in pre-treatment care with chronic infections and AIDS and (e) loss to follow-up before antiretroviral treatment (ART), (f) patients on treatment with non-suppressed (>500copies/mL) and suppressed viral load, and (g) loss to follow-up after treatment initiation. To incorporate the principles of TasP, we assumed minimal transmission risk for HIV-infected MSM with suppressed viral load Appendix\u00a0.23). The average difference in the number of new diagnoses in 2011 between basecase and 100 simulations was 4.9 persons (SD 3.12 persons)  and Neisseria gonorrhoeae (NG). HIV-infected MSM were assumed to have 4 specialist clinic visits, CD4 and viral load measurements in a year. For those on treatment, the ART cost reported locally was included. We adopted the CD4 level specific utility list applied in a previous cost-effectiveness analysis among MSM in Australia26. We assumed 3.5% annual discounted rate in the analysis26. List of cost and utility parameters is shown in Table\u00a0For each HIV negative MSM on PrEP, high adherence was defined as 87.5% (mid-point of 75% and 100%) usage and low adherence as 38% (mid-point of 1% and 75%) usage of daily oral PrEP, attending 4 visits at HIV specialist clinics with HIV testing, a yearly test for creatinine, syphilis, In the study, PrEP implementation was assumed to have started from 2017. We assumed that a proportion of susceptible MSM was on PrEP at the beginning of the year, with some dropping out in the remainder of the year. At the beginning of the following year, the total number of dropped-out users was replaced to maintain a constant coverage.basecase without PrEP (A1); with 10%, 30% and 90% coverage of PrEP (A2) involving both low-risk and high-risk MSM (i.e. non-targeting approach) with low or high adherence usage; and involving high-risk MSM only (i.e. targeting approach) (A3) with low or high adherence usage;test-and-treat without PrEP (B1); with 10%, 30% and 90% coverage of PrEP through a non-targeting approach (B2) with low or high adherence usage; and through a targeting approach (B3) with low or high adherence usage;To compare the relative impacts of PrEP implementation with improving engagement in the cascade of HIV care, we developed scenarios in the model and conducted cost-effectiveness analysis from 2017 onwards, with different coverage of PrEP in (A) basecase, and with (B) a high rate of diagnosis and treatment initiation :As it was obvious that low adherence PrEP would not be cost-effective, only scenarios with high adherence PrEP had been developed in the cost-effectiveness analysis.We performed two-way sensitivity analyses with different levels of PrEP coverage  in high- and low-risk MSM, stratified by high and low adherence in the epidemic model. We also developed hypothetical scenarios in high HIV incidence environment (\u22653 per 100 person-years) to analyse the impact of PrEP implementation strategies. For cost-effectiveness analysis, we performed sensitivity analyses for different pricing scale of PrEP drug cost .The opinions and assertions contained herein are private views of the authors and do not necessarily reflect those of the affiliating institutions. Part of the preliminary model projection results have been presented at Health Research Symposium 2017 in Hong Kong, and at Asia Pacific AIDS & Co-infections Conference (APACC) 2018 in Hong Kong [oral presentations].27).Among 1886 MSM cases with clinical data, the median age was 34 (IQR\u2009=\u200928\u201342), and 1541 (82%) were Chinese. For those with subtyping performed (1157 MSM), 254 (22%) belonged to subtype CRF01_AE, 835 (72%) to subtype B, and 68 (6%) to other subtypes. A total of 841 (45%) had a negative HIV test result before HIV diagnosis. Among them, 579 (69%) underwent the test \u22643 years before HIV diagnosis. By 2012, 1443 (77%) of MSM cases had initiated ART, after a median interval between HIV diagnoses and treatment initiation of 8 months (IQR\u2009=\u20092\u201329 months). Among those on treatment, 1286 (89%) cases had ever achieved viral load suppression (\u2264500/mL) by 2012 , 44 small clusters (four to ten connected nodes), 88 dyads or very small clusters (two to three connected nodes) and 447 isolates. The distribution of these clusters by subtype is shown in Fig.\u00a018.In the basecase model, the annual number of new diagnoses was projected to increase continuously from the year 2012 to 2021 Fig.\u00a0. Model eIf PrEP is implemented from 2017, it could avert 8% (10% high adherence PrEP) to 55% (90% high adherence PrEP) of total new infections above basecase scenario in 2017\u20132021 Table\u00a0. In the In the scenario of test-and-treat without PrEP, the proportion of new infections averted would increase from 6% in 2017 to 41% in 2021  and with high adherence, a non-targeting approach could avert an additional 5\u201324% of the total new infections in five years  to assess the situation in perspective. The impact is obviously high when targeting high-risk MSM for PrEP, as shown in the sensitivity analyses in Appendix\u00a013, our results illustrated positive impact of PrEP intervention on HIV epidemic control among MSM, despite the low incidence in the locality.In the deterministic compartmental model, we estimated that PrEP implementation since 2017 could avert 3\u201363% of total new MSM infections above basecase in Hong Kong in 2017\u20132021, the extent of which would vary with PrEP coverage and the effectiveness of implementing mixed interventions with the incorporation of test-and-treat intervention. Similar to other studies28. Although both studies suggested targeting MSM with higher sexual activity for PrEP, its definition was set at having more than one new sexual partner a year, with the adoption of a low threshold approach28. Our simulation results were however completely different from other PrEP modelling studies in low HIV incidence places that had adopted a targeted approach. Elsewhere, the results supported the prioritization of high-risk MSM for PrEP usage29. The discrepancy might have arisen from the different assumptions adopted for population mixing. Assortative mixing was assumed in our models, the results of which fitted well with the reported annual number of new diagnoses. We have developed a separate model with the incorporation of proportionate mixing pattern  approach could avert more new infections than offering PrEP exclusively to MSM belonging to one distinct risk category. The finding was in line with those from UK\u2019s modelling studiesAppendix\u00a0, which s31. A modelling study in Los Angeles projected that 59% new infections could be averted by a mixed PrEP and test-and-treat strategy30, and a study in San Diego projected 50% reduction of new infections by the mixed approach31.In the implementation of PrEP, it is important to focus on adherence, as high adherence PrEP would avert additionally 10% or more new infections than low adherence Appendix\u00a0ppendix\u00a0A33. While targeting 30% high risk MSM for PrEP was 11% more cost-effective than non-targeting approach, the proportion of new infections averted would be 12% lower than that of non-targeting approach. Combined with test-and-treat intervention, a non-targeting approach with 30% coverage could avert 8% more new infections, and was 3% in Plan B or 15% in Plan C more cost-effective than targeting approach in the five-year period.Taking the current high drug cost of PrEP  into consideration, PrEP intervention alone in the low HIV incidence setting does not appear to be cost-effective (at least USD1583136/QALYG). In the case of Hong Kong, a 93% reduction of the drug cost  is desirable in order to demonstrate PrEP\u2019s cost-effectiveness. Drug price as an important determinant of cost-effectiveness for PrEP is consistent with previous cost-effectiveness analyses in the published literature34, suggesting that a non-targeting approach might already be able to attract more high-risk than low-risk MSM for PrEP. Similar relationship between intention to use PrEP and risk behaviour was observed in people who inject drugs35. Naturally, informing MSM and connecting them with an accessible PrEP service should be prioritized, which can normally be achieved with the collaborative efforts of community organisation and strategic use of Internet36.It is important to note that the cost implicated in PrEP includes not just drug cost but the accompanying programme cost of establishing/running an accessible PrEP service (cost not included in this study), coupled with the means to enrol eligible persons, the latter depending naturally also on the approach to be adopted. Resources should also be spent to enhance adherence. For a targeting approach, the identification of people at high risk of infection, who may otherwise be hidden in the low HIV incidence population, is a challenge. It can be argued that if the impact of PrEP implementation via a targeting or non-targeting approach is similar, it might not be necessary to pay for this additional cost aiming to identify MSM with very high risk behaviours. From a previous study, high-risk MSM had higher intention for future PrEP use37. Third, only two types of sexual partnership, serial monogamy and random mixing were assumed, which might have underestimated the impact of concurrent partnership and group sex. We also assumed that the HIV transmission hazard of MSM was 1.2 times higher than heterosexuals. The value was determined under model calibration in our previous study22. As the basecase model estimation was close to the observed data , model fitness was implied. Fourth, the effectiveness of PrEP was categorized in two levels, corresponding to low and high adherence of PrEP. However, with different mode of PrEP usage, including daily oral, event-driven and time-driven, the adherence pattern and overall effectiveness of PrEP would be very different in real life situation38. The effectiveness of PrEP would likely increase with the optimization of regimens in the future. From our sensitive analysis, more new infections would be averted with the increasing effectiveness of PrEP. Fifth, as the occurrence of adverse events of PrEP is unlikely to be related to the implementation approach, it had not been included in the model. However, we acknowledged the impact of adverse events in risk benefit calculation, when the HIV infection risk is minimal with PrEP usage. Finally, cost-effective analyses have been conducted to provide a broader perspective in evaluating possible strategic approach to PrEP. We have included drug cost and monitoring cost in the analyses, on the assumption that programmatic cost would be similar irrespective of the approach adopted. This can be an over-simplification of the actual situation should PrEP become implemented. Furthermore, the cost-effectiveness analyses only estimate a five-year period instead of longer duration. The incremental cost per QALYG might have been overestimated.This study carries some limitations. First, bisexual individuals were subsumed as MSM for analytic simplicity. Theoretically they could function as the epidemiological link, allowing HIV to spread from MSM to heterosexual population. In models projecting both heterosexual and MSM population, especially in the presence of a high proportion of bisexuals, further adjustment would be needed when applying our model structure. Second, the impact of condom usage on transmission risk was considered during high and low risk group classification, and as such, condom intervention and risk compensation (i.e. less condom use after PrEP usage) had not been modelled in the analyses. The potential impacts of sexually transmitted infections (STI) had not been factored in, though we acknowledged the potentially higher transmission risk of STI among PrEP usersIn conclusion, for low incidence places such as Hong Kong, PrEP could contribute to the control of the HIV epidemic in MSM in addition to the benefits from adopting a test-and-treat strategy. Offering PrEP without prioritization by behavioural risk in moderate coverage (say 30%) would be a feasible and cost-effective means for averting more new infections if PrEP drug cost is low enough. This strategy would likely be applicable for places with similarly low HIV incidence in particular in Asia, on the assumption that the networking patterns of MSM were similar. Our study shows that it is important not just to establish the baseline HIV incidence but consider the strategic approach for PrEP implementation in its development as part of a city/country\u2019s HIV prevention programme.Appendix A"}
{"text": "Pre-exposure prophylaxis (PrEP) with daily oral tenofovir/emtricitabine dramatically reduces HIV risk in men who have sex with men (MSM). However, uptake is slow worldwide.We administered anonymous cross-sectional questionnaires to MSM presenting for anonymous HIV testing at a Toronto sexual health clinic at four successive time points during the period 2013\u20132016. We assessed trends in PrEP awareness, acceptability, and use over time using the Cochran-Armitage Trend Test, and identified barriers to using PrEP by constructing \u201cPrEP cascades\u201d using 2016 data. We assumed that to use PrEP, MSM must (a) be at risk for HIV, (b) be at objectively high risk (HIRI-MSM score \u2265\u200910), (c) perceive themselves to be at medium-to-high risk, (d) be aware of PrEP, (e) be willing to use PrEP, (f) have a family doctor, (g) be comfortable discussing sexual health with that doctor, and (h) have drug coverage/be willing to pay out of pocket.p\u2009<\u20090.0001), reaching 91.3% and 5.0%, respectively, in the most recent wave. Willingness to use PrEP rose to 56.5%, but this increase did not reach statistical significance (p\u2009=\u20090.06). The full cascade, ABCDEFGH, suggested few could readily use PrEP under current conditions (11/400\u2009=\u20092.8%). The largest barriers, in descending order, were low self-perceived HIV risk, unwillingness to use PrEP, and access to PrEP providers.MSM participants were mostly white (54\u201359.5%), with median age 31\u00a0years (IQR\u2009=\u200926\u201338). PrEP awareness and use increased significantly over time (both To maximize its potential public health benefits, PrEP scale-up strategies must address self-perceived HIV risk and increase access to PrEP providers. Men who have sex with men (MSM) continue to see stable or increasing rates of HIV incidence worldwide  April\u2013June 2013, (2) May\u2013August 2014, (3) November 2014\u2013April 2015, and (4) May\u2013August 2016. Adult MSM who understood English were eligible to complete the survey immediately after their point-of-care HIV test or within 2\u00a0weeks if they returned to the study site. All participants were offered a CAD$10 gift card.Hassle Free Clinic is a busy sexual health clinic in downtown Toronto that conducts approximately 5400 point-of-care HIV tests among MSM every year. Of these, over half are performed at four community-based satellite clinics across the city. Demographic characteristics and HIV positivity rates are generally similar across sites. Collectively, Hassle Free Clinic has the highest positivity rate (1.7%) of all 38 anonymous HIV testing sites in Ontario .Questionnaire content varied slightly between waves 1 and 4, but included demographic characteristics, sexual practices, recreational drug use, and perceived HIV risk, as well as awareness of, willingness to use, and current use of HIV prevention technologies such as post-exposure prophylaxis (PEP) and PrEP.We quantified HIV risk using the HIV Incidence Risk Index for MSM (HIRI-MSM), a seven-item scale that incorporates (1) age, (2) number of male partners, (3) number of HIV-positive partners, (4) frequency of condomless receptive anal sex, (5) frequency of condomless insertive anal sex with HIV-positive partners, (6) amyl nitrate use, and (7) amphetamine use in the past 6\u00a0months  to reduce their risk of HIV infection. This pill contains two anti-HIV drugs (tenofovir/emtricitabine or Truvada\u00ae) and research suggests that it is relatively safe and is over 90% effective if taken consistently. It is much less effective if not taken every day and it does not protect against other STIs. Taking PrEP would require a visit to the doctor every 3 months in order to be tested for HIV, STIs and side effects. Truvada\u00ae was recently approved to be used for PrEP in Canada.\u201d This description was modified for each wave of survey administration, in keeping with the approval status and available data on PrEP efficacy at the time. Each version was pilot-tested with five participants for clarity and face validity.Awareness of PrEP was defined as responding \u201cyes\u201d to the question, \u201cBefore today, had you ever heard of PrEP?\u201d Willingness to use PrEP was defined as responding with either \u201cagree\u201d or \u201cstrongly agree\u201d on a five-point Likert-type scale to the statement, \u201cI would be interested in taking PrEP to reduce my current risk of HIV infection\u201d. Participants were also asked to indicate their reasons for being interested or not interested in PrEP, using a list of options derived from literature review and discussions with community members, including a free-text \u201cother\u201d field.We summarized participant characteristics using descriptive statistics, with continuous variables summarized by measures of central tendency and dispersion and categorical variables by proportions. We used Kruskal-Wallis and chi-square tests to assess for differences in participant characteristics between survey waves.To achieve our primary objective, we calculated the proportion of respondents in each survey wave who had each outcome of interest , and conducted Cochran-Armitage Trend tests to assess for linear increasing trends in these proportions.p\u2009<\u20090.01), only one was considered for inclusion in the multivariable model, based on model fit (AIC). We constructed models using forward selection, where variables were added one at a time and retained if statistically significant at a threshold of alpha\u2009=\u20090.10  and analyzed them visually for gaps. We repeated this process using a higher HIRI-MSM score of \u2265\u200925 for defining high risk, as suggested by our prior work and by cost-effectiveness analyses  with reasonable precision, as previously described  to 58.3% (95% CI\u2009=\u200953.3\u201363.3%) to 71.8% (95% CI\u2009=\u200967.2\u201376.1%) to 91.3% (95% CI\u2009=\u200988.0\u201393.8%)  suggested that only 2.8% (11/400) participants had no individual or system barriers to using PrEP, similar to our previous findings Fig.\u00a0. The greSince MSM at high objective HIV risk (HIRI-MSM \u2265\u200910) who indicate willingness to use PrEP represent an important group that should be prioritized for PrEP initiation, we tabulated perceived barriers to PrEP initiation in this group. While the most common barriers were related to financial access, including not having private drug insurance  or believing that PrEP was not covered by one\u2019s private insurance , other common concerns included simply not having looked into getting PrEP yet , not having a doctor , and not feeling comfortable asking doctors for PrEP , suggesting that efforts to increase the availability of trained PrEP providers and more actively facilitate linkages with PrEP services could increase uptake.Those with high objective HIV risk who were unwilling to use PrEP are another group whose perspectives are important to understand Table . Common p\u2009=\u20090.09) and less likely to cite interest in condomless sex as reasons .Finally, we examined reasons for PrEP interest among those not at high objective HIV risk who nevertheless were willing to use PrEP Table . OverallIn this series of four surveys among Toronto MSM undergoing anonymous HIV testing during the period 2013\u20132016, we observed a significant increase in PrEP awareness over time, reaching 91.3% in 2016. Although PEP awareness, PEP use and higher objective HIV risk were predictors of PrEP awareness in univariable analyses, time remained the strongest independent predictor when building the multivariable model. This association with time did not, however, correspond to a significant increase in willingness to use PrEP over time, which was 56.5% in 2016. In addition, PrEP uptake was low, with only 5.0% in the most recent survey reporting ever using PrEP.The high degree of PrEP awareness in our 2016 sample is striking, and given the lack of concerted public health messaging about PrEP in Canada, is testament to the capacity of communities and healthcare providers to raise awareness about important health interventions at a population level. Conduct of Canada\u2019s first PrEP demonstration project in the city from 2014 to 2016 , these changes reflect the changing contexts in which respondents formulated their opinions about PrEP, and were necessary to ensure that information provided to participants about PrEP was up-to-date. Wording changes also necessitated imputation of some values when calculating HIRI-MSM scores for survey waves 1 and 2; such changes may have contributed to the small observed differences in participant characteristics between waves but would not have affected our primary or secondary outcomes. Third, HIRI-MSM has limited sensitivity for identifying HIV seroconverters in some contexts, and thus may have underestimated the proportion of those who should use PrEP (Lancki et al. Our study identified increasing awareness and consistent, moderate willingness to use PrEP among at-risk Toronto MSM. To maximize the potential public health benefit or PrEP, next steps should include developing strategies for helping men better understand their HIV risk, publicizing the excellent safety and efficacy of PrEP, training providers for PrEP delivery, and identifying funding strategies to facilitate PrEP use."}
{"text": "To assess the safety profile, pharmacokinetics, pharmacodynamics andpreliminary antitumour activity of fixed-dose SHR-1210, a novel anti-PD-1antibody, in advanced solid tumours.A total of 36 patients with advanced solid tumours receivedintravenous SHR-1210 at 60\u2009mg, 200\u2009mg and 400\u2009mg  until disease progression or intolerable toxicity.The concentration of SHR-1210 was detected for pharmacokinetics, and receptoroccupancy on circulating T lymphocytes was assessed for pharmacodynamics.No dose-limiting toxicities were observed. Maximum administered dosewas not reached. Most adverse events were grade 1 or 2. Treatment-related severeadverse events were found in two patients. No treatment-related death wasreported. Two complete responses  and sevenpartial responses were seen. In responders, the median follow-up time was 16.0months (range 8.3\u201319.5), and the median duration of response was not reached(range 2.7\u201317.5+ months). The half-life of SHR-1210 was 2.94 d, 5.61 d and 11.0 dfor 3 dose levels, respectively.Our results demonstrated a promising antitumour activity and amanageable safety profile of SHR-1210, displayed an explicit PK evidence of thefeasibility of fixed dose, and established the foundation for furtherexploration. To the best of our knowledge, there are no phase 1 clinicaltrials evaluating the efficacy of anti-PD-1 antibodies at fixed dose.Monoclonal antibodies are usually given based on the body weight,which has recently been re-evaluated because of the specific properties, and theincreased convenience and improved safety of the administration paradigm of fixeddose.Based on this consideration, we initiated this phase 1 trial(NCT02742935) of PD-1 blockade with a novel humanised high-affinity IgG4-kappamonoclonal antibody SHR-1210 in 36 patients with advanced solid tumours, assessingthe safety profile, preliminary antitumour activity, PK and receptor occupancy (RO)rate at fixed doses, establishing the feasibility of this dosing strategy and thebasis for further clinical expansion.Eligible patients had documented advanced solid tumours; an agebetween 18 and 75 years old; an Eastern Cooperative Oncology Group (ECOG)performance status of 0 or 1 ; had experienced PD orrecurrence after at least one systemic treatment for advanced or metastaticdisease; at least one measurable lesion according to Response Evaluation Criteriain Solid Tumors (RECIST) (version 1.1); adequate haematologic, hepatic and renalfunction. Patients with brain metastasis were enrolled only when the lesions hadbeen stable for at least 3 months. Patients with a history of or active autoimmunedisease, a concomitant secondary cancer, history of organ transplantation orPD-1/PD-L1 treatments, active hepatitis B or C viral infection, or ongoingsystemic immunosuppressive therapy were excluded. Previous cancer treatment,radiotherapy or radiosurgery must have been completed at least 4 weeks before theenrolment. All patients provided written informed consent before theenrolment.This multicenter, single-arm, open-label, phase 1 clinical trial wasapproved by the institutional review board and independent ethics committee of theNational Cancer Center, Cancer Hospital, Chinese Academy of Medical Sciences. Itwas conducted in accordance with the Declaration of Helsinki and the internationalstandards of good clinical practice. Informed consents had been obtained frompatients.This study consisted of an initial dose-escalation and subsequentexpansion phase. During dose-escalation, patients were treated with SHR-1210 at afixed dose of 60\u2009mg every 2 weeks, with escalation to 200 and 400\u2009mg. We chosethese dose levels mainly based on the PK and toxicity properties of SHR-1210 givenin previous phase 1 study conducted in Australia in 2015. Meanwhile, 200\u2009mg Q3W ofother anti-PD-1 antibodies, such as Pembrolizumab and Nivolumab, have both beenconfirmed to have promising efficacy and tolerability in several tumours and havebeen approved in worldwide. Based on these information and significant efficacysignal in the 60\u2009mg cohort, the dose escalation did not proceed beyond 400. Aquantity of 400\u2009mg was the preplanned maximum administered dose. The drug wasadministered as an intravenous infusion at week 1, week 5, and then every 2 weeks.The first cycle  was designed for observation of dose-limitingtoxicity (DLT), which was defined as \u2265grade 2 uveitis, \u2265grade 2 interstitialpneumonia, \u2265grade 3 non-haematologic and \u2265grade 3 haematologic adverse events(AEs) related to study medications occurring during the first cycle. Doseescalation proceeded when 3 patients had completed the safety observation periodat a given dose level without any DLT, otherwise 3 extra patients were required atthis dose level, and if the 3 extra patients developed DLT, the dose escalationterminated, the dose prior to which was defined as maximum-tolerated dose (MTD).Intra-patient dose escalation was not permitted. A modified definition of DLT wasincorporated in the study\u2019s protocol. Delayed DLT such as severe immune-relatedAEs was also recorded for safety analysis after the first 4 weeks, but notinfluencing the dose escalation. No escalation was continued after 400\u2009mg groupeven if no DLT was observed.On the basis of initial signals of activity, subsequent expansioncohorts of extra 9 patients each were enrolled at 60, 200 and 400\u2009mg. Alltreatments were to continue until intolerable toxicity, confirmed diseaseprogression, death or withdrawal of consent. Treatment beyond initial diseaseprogression (PD) was allowed in clinically stable patients  at the discretion of the investigator.Safety evaluation, including clinical examination and laboratoryassessments were conducted for all patients treated with SHR-1210 at baseline andregular intervals. Notably, the laboratory assessments for endocrine function wererepeated every 4 weeks, while the liver and kidney function tests repeated every 2weeks. SHR-1210 administration could be interrupted or delayed forprotocol-defined reasons, but dose modification was not permitted. The severity ofall AEs was graded according to the National Cancer Institute Common TerminologyCriteria for Adverse Events (NCI CTCAE), version 4.03. General AEs were handledbased on established safety guidelines. Specific AEs, such as immune-related AEswere handled according to the study protocol, as well as those clinical routinelyused guidelines. Patients could receive the treatment again after the AEsrecovered to initial state or grade 1. Severe adverse event (SAE) was defined asany event lead to death, life threaten, hospitalisation or prolongedhospitalisation, forever or severe deformity or dysfunction, innate abnormalitiesor birth defect and other vital medical events deteriorating the patient\u2019sdisease.Independent radiologic evaluation by CT or MRI was done at baselineand every 8 weeks during the first 6 months, and every 12 weeks thereafter.Overall response rate (ORR) was summarised as the proportion of response-evaluablepatients who had a best response of complete response (CR) or partial response(PR), based on RECIST, version 1.1, as assessed by independent radiologists.Disease control rate (DCR) was defined as the proportion of CR, PR and stabledisease (SD) patients.The concentration of SHR-1210 was detected for PK studies. Plasmasamples for SHR-1210 PK analysis were collected at \u22120.5\u2009h, 5\u2009min (\u00b12\u2009min), 2\u2009h(\u00b15\u2009min), 6\u2009h (\u00b15\u2009min), 24\u2009h (\u00b15\u2009min), 48\u2009h (\u00b130\u2009min), day 8 (\u00b160\u2009min), day 15(\u00b160\u2009min), day 22 (\u00b160\u2009min) from the initiation of drug in Cycle 1, and \u22120.5\u2009h,5\u2009min (\u00b12\u2009min) from drug administration on day 1 and day 15 from Cycle 2. Sampleswere stored at \u221280\u2009\u00b0C until measurement. Serum concentrations of SHR-1210 weredetermined using a validated enzyme-linked immunosorbent assay (ELISA) by Covance(Shanghai) with a lower limit of quantification (LLOQ) of 157\u2009ng/mL. Thebioanalytical method validation of the ELISA was performed based on the FDA\u2019srecommendation, including the validation of \u201cCalibration Standards\u201d, \u201cQualityControls Intra and Inter Assay Bias and Precision\u201d, \u201cQuality Control Samples\u201d,\u201cSelectivity\u201d, etc. Anti-PD-1 antibody was obtained from Sino Biological andanti-human IgG (Fab specific) peroxidase antibody produced in goat was obtainedfrom Sigma-Aldrich. RO on circulating T lymphocytes was assessed forpharmacodynamics studies. The plasma samples for pharmacodynamics studies werealso collected at above-mentioned time points expect for 5\u2009min (\u00b12\u2009min) from drugadministration on day 1 and 15 from Cycle 2. RO of SHR-1210 was determined as theratio of CD45+/CD3+ cells after incubation with control IgG4 (in vivo bindingsites of SHR-1210) to that observed cells after incubation with SHR-1210 .11 For cases in which the tissue sample had notbeen optimally collected or prepared or in which PD-L1 expression could not beassessed, the PD-L1 status was categorised as unevaluable.We measured PD-L1 expression in pretreatment, archival tumoursamples with an investigational version of the Human PD-L1 ImmunohistochemistryKit using the 6E8 antibody .For each sample, the membrane expression of PD-L1 in tumour cells was determinedby two independent pathologists blinded to the clinical data. PD-L1 cell scoreswere generally based on a single section. All the neoplastic cells were scorable.PD-L1 positivity was defined as \u22655% of tumour cell membranestaining.All statistical tests for PK and correlative studies analyses useda two-sided significance level 0.05, adjusted for multiple comparisons. TheClopper-Pearson method was used to calculate the 95% CI for ORR. Theprogression-free survival (PFS) were estimated with the Kaplan\u2013Meier method. PKand pharmacodynamics parameters of SHR-1210 were calculated usingnon-compartmental approaches by WinNonlin 5.3 software. SPSS statistics version 22software was used for all analyses.A total of 36 patients with advanced solid tumours, includingoesophageal squamous cell carcinoma (ESCC), gastric cancer, triple-negative breastcancer (TNBC), colorectal cancer, non-small-cell lung cancer (NSCLC),nasopharyngeal cancer (NPC), hepatocellular cancer, bladder cancer and cervicalcancer, were included between April 26, 2016 and December6, 2016. The median treatment duration was 3.2months (range 0.5\u201319.3), and eight patients remained on study treatment. A totalof 28 (77.8%) patients discontinued SHR-1210. The most common reason for treatmentdiscontinuation was disease progression (24/28). Two patients stopped SHR-1210because of lung infection that may not related to the study treatment. One patientdied from upper gastrointestinal haemorrhage, which thought to be related totumour progression. The other patient stopped SHR-1210 because of grade IVneutropaenia.The MTD was not reached, and no DLT (including delayed DLT) wasobserved in three dose groups. At the date of analysis, 35 patients 97.2%) hadexperienced at least one AE, and 32 (88.9%) of them were treatment-related AE(TRAE) (Table\u00a0% hadexpTwo patients (5.6%) had treatment-related SAE. One patient withcervical cancer (200\u2009mg) developed grade IV neutropaenia and thrombocytopenia,leading to the termination of treatment. The grade 4 neutropaenia appeared 12 daysafter the first dose of SHR-1210. The results of autoimmune antibodies tests wereall negative. Patient refused bone marrow aspiration. After continuous treatmentof granulocyte colony-stimulating factor and thrombopoietin, neutropaeniapersisted for 3 weeks and patient recovered without any signs of infection. Theother patient with ESCC (60\u2009mg) experienced grade 1 elevation of troponin, leadingto hospitalisation and suspending of treatment. After coronary angiographyexcluding the possibility of myocardial infarction, he resumed SHR-1210 andresulted in sustained partial response.12 All the patients with hypothyroidism had nosymptoms and were successfully treated with replacement therapy. irAEs greaterthan grade 3 were observed in 2 patients (5.6%): grade 4 neutropaenia, anaemia andthrombocytopenia in one patient (2.8%); and grade 3 diarrhoea in the other patient(2.8%).Immune-related AEs (irAEs) were observed in 31 patients (86.1%),the most of which were reactive capillary hemangioma, pruritus, hypo- orhyperthyroidism, abnormal liver function test, diarrhoea and skin rash, etc. Mostof the irAEs were grade 1 or 2. The incidence of hypothyroidism in patients whohad normal thyroid function at baseline was 12.1% (4/33), which was similar tothat of other anti-PD-1 antibodies.Based on independent central review assessment, antitumour activitywas observed at all doses Fig.\u00a0. TwopatAt the time of the data cutoff, 28 patients (77.8%) had diseaseprogression and 22 patients had died. The median PFS as assessed by independentreview and median OS were 1.8 months (95% CI: 1.6\u20132.0) and 9.8 months (95% CI:7.3\u201312.3), respectively. The Kaplan\u2013Meier analysis estimated a 6-month PFS rate of38.4% (95% CI: 22.3\u201354.5) and a 6-months OS of 80.6% (95% CI: 67.7\u201393.5). Amongthe 28 patients who had progressive disease, progression occurred in preexistingtarget lesions (10 patients), new metastatic sites (3 patients), or both (15patients). There are no significant differences among 3 dose groups in terms ofPFS or OS.  of SHR-1210increased in a dose-dependent manner from 60 to 400\u2009mg, ranging from 2.94 to 11.0days; similarly, Cmaxand AUC were also directly dose-dependent. After repeated doses, the accumulationratio of SHR-1210 at Cmin from C1D1 to C5D1 was 2.54\u20133.07 atsteady state (1st infusion in Cycle 5); whereas, the accumulation index at the endof infusion (Ceoinf)ranged from 1.08 to 1.53  after 1st infusion of Cycle 5\u00a0was 67,77 and 76% for 60, 200 and 400\u2009mg, respectively.The PD-1 RO results indicate that SHR-1210 has high affinity toPD-1after a single-intravenous infusion, which is dose-dependent and with a meanpeak occupancy of 85%  , and progressivedisease for nine patients (six ESCC and two gastric cancer). Notably, the PD-L1expression of tumour-infiltrating mononuclear cells in the patient with gastriccancer who experienced complete response was relatively high (30%).To the best of our knowledge, this is the first study reporting theantitumour activity, safety and PK of SHR-1210, a novel anti-PD-1 antibody at afixed dose in heavily-treated patients with advanced solid tumours, indicating theclinical potential of SHR-1210 due to its promising antitumour activity and amanageable toxicity profile.4 The data of this phase I clinicaltrial demonstrated that 25% of the patients treated with all doses of SHR-1210 haddurable objectives responses. The ORR and DCR of ESCC was 21.4 and 42.9%, slightlyhigher than those treated with nivolumab reported in a phase II clinical trial .13 The ORR of stomach cancer, lung cancer, NPC, livercancer, bladder cancer was 20, 33.3, 33.3, 50, 100%, respectively, not completelyconsistent to the previous reported data,4 which may be explained by the limited samplesize, yet still providing a comparative clinical efficacy with other checkpointinhibitors. Notably, no responses or disease control could be observed intriple-negative breast cancer and cervical cancer. In the previously reportedclinical trials on immunotherapy in patients with breast cancer, immune checkpointinhibition like pembrolizumab and atezolizumab demonstrated a response rate of 18.5and 24%, respectively.15In terms of cervical cancer, the ORR of pembrolizumab in PD-L1 positive patients was17%, and the responses were long-lasting with a mean duration of 26weeks.16All these results should be interpreted with caution due to the unselected patientsregardless of PD-L1 expression and the small sample size in this study.The inhibition of PD-1 displays a wide spectrum of clinicalantitumour activity among multiple tumours.18Interestingly, two patients experienced PD after treatment of SHR-1210, followed bysubsequent remission or stable status after continuous treatment with the immunecheckpoint inhibitor. Response after initial progression, which would otherwise beclassified as PD by RECIST 1.1, is described as \u201cpseudo-progression\u201d. This achallenging phenomenon during immune checkpoint inhibitor treatment, as severalstudies had reported,20and that is why we need to confirm the response at least 4 weeks after the firstevaluation of PD, in order to avoid the premature termination of treatment becauseof pseudo-progression, offering the necessity of the combination or alteration ofresponse evaluation criteria from conventional RECIST 1.1 to immune-related responsecriteria (iRECIST).21In addition to the responses, durable objective responses were alsonoteworthy in multiple types of tumours. Within the median follow-up time of 10.1months, the median duration of response was not reached. The longest duration hasreached 17.5+ months, and the response was still lasting. The relativelylong-lasting duration of response was similar with those treated with pembrolizumaband nivolumab.22 suggesting this therapy could be delivered in anoutpatient setting. The most commonly reported AE was reactive capillary hemangioma, which appeared after the initiation of treatment and regressedspontaneously both during and after treatment. Despite the notably high incidence,no patients discontinued or postponed the treatment due to this AE. Although,immune-related skin events were not unexpectedly, reactive capillary hemangioma is arare phenomenon and has never been reported in other anti-PD-1 antibodiespreviously. The mechanism of capillary hemangioma was still under investigation,with a possible explanation of the imbalance between enhancers and inhibitors ofangiogenesis as several reports suggested.24 The investigation of the mechanism of capillaryhemangioma induced by SHR-1210 is ongoing.Most of the toxicities reported in this study were grade 1 or 2,which could be resolved with appropriate supportive treatment, and were consistentwith other previously reported anti-PD 1 antibodies,7 Aquantity of 200\u2009mg Q3W of pembrolizumab has been confirmed to have comparableefficacy and tolerability in melanoma and NSCLC clinical trials. Based on PKproperties of given pembrolizumab either in weight-based or fixed doses, studiesdemonstrated that both dosing strategies were appropriate.25 With a similar maximal efficacyand acceptable tolerability, the administration of pembrolizumab at fixed dose wasapproved in NSCLC and head and neck squamous cell carcinoma in the UnitedStates,27 and is continuing to beinvestigated in trials for various indications. For SHR-1210 in patients withadvanced solid tumours, our results showed some correlation trends of patients\u2019 bodyweight with PK properties of SHR-1210, but not with receptor occupancy rate.Meanwhile, the CV% for the exposure of SHR-1210, as shown in Table\u00a0Another critical question this study brought up is that can anti-PD-1antibody at fixed-dose reach the comparable clinical efficacy with given based onbody weight. Dosing of therapeutic monoclonal antibodies is usually given based onbody weight. However, this traditional dosing paradigm has recently beenre-evaluated because of the specific properties and the increased convenience,elimination of wastage, improved safety, and improved compliance of fixeddose.28 and it\u2019s one of the most vitalparameters to determine the recommended dose of the drug. Our data display that thedrug concentration could be basically maintained higher than 2000\u2009ng/ml to realisesufficient RO saturation within 28 days after the initial infusion at a dose notlower than 200\u2009mg. Based on the above-mentioned studies and analysis, SHR-1210 givenat a fixed dose of 200\u2009mg could display a sufficient clinical efficacy and haveacceptable tolerance. Although, the frequency of administration requires clinicalsupport from further studies, the fixed dose of 200\u2009mg could be the recommended dosein the further clinical expansion.The pharmacodynamics of SHR-1210 were assessed according to PD-1 ROon circulating T lymphocytes. The RO is an important factor to test whether the drugdevelops biological activity by determining whether the pathway leading toantitumour activity is effectively saturated,29A series of trials have enroled only patients with PD-L1 positivetumours.17 Our data also suggest apossible association between anti-tumour activity and higher PD-L1 expression ontumour cells, although the number of patients is too small to make definiteconclusions. It\u2019s premature to assert the validity of PD-L1 as predictive biomarkerin patients treated with SHR-1210.Data from several studies suggested improved response of anti-PD-1antibodies in patients with PD-L1 positive tumours.In summary, our results demonstrated a promising antitumour activityand a manageable safety profile of SHR-1210 in pretreated patients with advancedsolid tumours, displayed an explicit PK and RO evidence of the feasibility of fixeddose, and determined the recommended dose of 200\u2009mg.Supplementary Figure 1Supplementary Figure 2Supplementary Figure 3"}
{"text": "Extracellular vesicles (EVs) play a central role in intercellular communication, which is relevant for inflammatory and immune processes implicated in neurodegenerative disorders, such as Parkinson\u2019s Disease (PD). We characterized and compared distinctive cerebrospinal fluid (CSF)-derived EVs in PD and atypical parkinsonisms (AP), aiming to integrate a diagnostic model based on immune profiling of plasma-derived EVs via artificial intelligence. Plasma- and CSF-derived EVs were isolated from patients with PD, multiple system atrophy (MSA), AP with tauopathies (AP-Tau), and healthy controls. Expression levels of 37 EV surface markers were measured by a flow cytometric bead-based platform and a diagnostic model based on expression of EV surface markers was built by supervised learning algorithms. The PD group showed higher amount of CSF-derived EVs than other groups. Among the 17 EV surface markers differentially expressed in plasma, eight were expressed also in CSF of a subgroup of PD, 10 in MSA, and 6 in AP-Tau. A two-level random forest model was built using EV markers co-expressed in plasma and CSF. The model discriminated PD from non-PD patients with high sensitivity (96.6%) and accuracy (92.6%). EV surface marker characterization bolsters the relevance of inflammation in PD and it underscores the role of EVs as pathways/biomarkers for protein aggregation-related neurodegenerative diseases. A major current medical need in the field of neurology is the identification of reliable biomarkers in vivo for the diagnosis of neurodegenerative diseases. Parkinson\u2019s Disease (PD) is the second most common neurodegenerative disorder of the elderly, characterized by the progressive loss of dopaminergic neurons in the substantia nigra . To dateExtracellular vesicles (EVs) are emerging as novel and sensitive biomarkers for neurodegenerative diseases ,5. EVs aIn a previous work, we demonstrated that distinctive pools of plasma-derived EV surface markers related to inflammatory and immune cells stratified patients with PD and AP according to the clinical diagnosis. We characterized distinctive EV subpopulations in plasma by simultaneously immunophenotyping 37 different membrane proteins using a flow cytometry multiplex bead-based platform ,13 and tTherefore, the aims of the present study were: (1) to characterize CSF-derived EVs in healthy subjects and patients with PD, MSA and AP-Tau; (2) to compare EVs profiling in matched CSF and plasma samples of PD and AP patients; (3) to improve our previous diagnostic model, based on plasma-derived EVs by integrating information provided by CSF-derived EVs immunophenotyping.A total of 16 patients, for which matched plasma and CSF samples were analyzed in the current study, made up the optimization cohort: 4 idiopathic PD, 4 probable MSA and 4 probable AP-Tau, among which 3 had probable progressive supranuclear palsy and 1 had possible corticobasal degeneration. The plasma discovery cohort included 84 subjects  9]. Sub. Sub9]. g at 10 \u00b0C, to eliminate cellular components; then, three consecutive centrifuges were performed to further purify the plasma, eliminating apoptotic bodies and larger EVs . We previously demonstrated no significant change in flowcytometric analysis by MACSPlex assay of plasma samples with and without EV enrichment by ultracentrifugation [In total, 10 mL of blood was collected into anticoagulant-EDTA tubes, after at least 4 h fasting. The following protocol was performed to obtain EV enriched plasma  Figure a: samplefugation . Samplesg at 4 \u00b0C). Pellets were resuspended in 30 \u00b5L of particle-free PBS. The storage period varied among samples according to the consecutive enrollment of subjects in the study, between 2015-07 and 2020-10.Five mL of CSF was collected into 15 mL polypropylene tubes, and immediately frozen a. After g at 4 \u00b0C. The obtained pellet was resuspended in 100 \u00b5L of particle-free PBS. A total of 1 \u00b5L of ultraconcentrated plasma or CSF was diluted in particle-free PBS\u20141:500 and 1:250, respectively. NTA analyses were performed as previously described [Nanoparticle concentrations and diameters were measured by NanoSight LM10  equipped with a 405 nm laser and Nanoparticle Tracking Analysis NTA 2.3 software . Only for NTA analysis, to rule out a confounding effect of ultracentrifugation on EV amount and diameter, plasma samples (100 \u00b5L) were centrifuged akin to CSF samples for 18 h at 100,000\u00d7 escribed .The screening approach  was previously described ,13 and iIn total, 60 \u00b5L of plasma and 30 \u00b5L of ultracentrifuged CSF were added to the MACSPlex Buffer solution  and analyzed with MACSQuant Analyzer-10 flow cytometer . As a blank control we used MACSPlex Buffer incubated with beads and detection antibodies. Median fluorescence intensity (MFI) for each EV surface marker was normalized by the mean MFI for specific EV markers . All analyses were based on normalized MFI (nMFI) values. Samples were analyzed blind to the clinical diagnosis.Tests for the reliability/specificity of MACSPlex human Exosome Kit for EVs and for the technical consistency and reproducibility of the assay were performed in our previous work .Statistics was performed using IBM SPSS Statistics 22.0 , PYTHON 2.7 , and GraphPad PRISM 7.0a . A Kolmogorov\u2013Smirnov test was applied to evaluated variable distribution. Non-normally distributed variables  were expressed as medians (interquartile range) and analyzed by Kruskal\u2013Wallis\u2019 test. Normally distributed variables (age) were expressed as mean \u00b1 standard deviation (SD) and analyzed by 1-way ANOVA test with Bonferroni\u2019s correction for multiple comparisons. Categorical variables (sex) were expressed as absolute number and percentage (%) and analyzed by \u03c7\u00b2 (when applicable) or Fisher\u2019s tests. Matched measurements (plasma vs. CSF), variables were analyzed by Wilcoxon pairs signed rank test.Supervised learning algorithms were used to combine levels of expression of single EV surface markers in a specific EV surface marker signature and discriminate patients according to clinical diagnosis. Linear discriminant analysis was used as a feature reduction strategy to build the 3D canonical plots ; canonical components were calculated from the weighted linear combination of expression levels for the 37 EV markers in order to maximize the separation between the 4 groups ; each point represents a patient and spheres include patients with a linear combination coefficient that falls within the mean of canonical components 1, 2, and 3 \u00b1 SD. The diagnostic models were built exploiting a random forest (RF) classification algorithm, as previously reported ,22,23. BThe basic RF models were built on the expression of 17 EV surface markers , which were demonstrated to be differentially expressed in plasma samples in HC, PD, MSA, and AP-Tau in our previous study [The integrated version of RF models  was built selecting only markers expressed in CSF- and plasma-derived EVs from patients with PD , MSA , or AP-Tau . Integrated models were directly validated on the original discovery cohort. A representative classification tree was shown for each model, and a confusion matrix reported accuracy, sensitivity, specificity, positive and negative predictive values.p > 0.05 for all comparisons). The plasma discovery cohort included 84 patients from our previous study [The optimization cohort included 16 patients: 4 PD, 4 MSA, 4 AP-Tau , and 4 healthy controls (HC). These subjects underwent plasma and CSF collection for paired flow cytometry analysis. Clinical characteristics are summarized in us study  and was p = 0.048); this difference was mainly due to larger vesicles  revealed higher concentration of CSF-derived nanoparticles/mL in PD compared to HC . Plasma samples showed higher numbers of nanoparticles/mL compared to CSF, even after stratification for EV diameter , compared to CSF (p = 0.005). Among the 37 EV surface markers analyzed in paired plasma vs. CSF samples, 5 markers were differentially expressed in the PD group, 11 in MSA, and 8 in AP-Tau. All these markers were more highly expressed in plasma than CSF except for CD9 in the MSA group . A random forest (RF) model (we will refer to this model as \u201cbasic\u201d throughout the present manuscript) was built combining levels of expression of these EV markers . Among tn = 84; The level 1 RF basic model  , generated via outward budding of the plasma membrane, rather than exosomes (40\u2013120 nm) produced in multivesicular bodies via endosomal pathway . Indeed,Regarding the EV immune profiling by MACSPlex human exosome assay applied to CSF-derived EVs, no statistically significant differences were observed in the 37 surface markers between groups. This is certainly due to the main limitation of this explorative study which is the low number of subjects analyzed in each diagnostic category. However, the simultaneous quantification of multiple EV markers increased the power of the assay and displayed different EV profiles of expression in subjects with PD and AP vs. HC, which allowed a good discrimination of patients in accordance with the clinical diagnosis by linear discriminant analysis. Of interest, PD and AP patients expressed higher amounts of HLA-I, CD8, CD2, CD3, CD14 and CD20 in CSF, while no or very low detection was observed in HC, suggesting a CNS activation of the immune system, in particular of the T cell-mediated immunity with particular emphasis on intracellular endogenous synthetized antigens that involves the activation of HLA class I  and are CD105 is highly expressed in CSF of PD and MSA. Even if it is used as an endothelial cell marker during angiogenesis , it was Finally, levodopa represents the first-line therapy in PD. Several drugs may influence the mechanism of biogenesis and release of EVs ; howeverThis is an explorative study and the low number of subjects in the CSF cohort is certainly a limitation; therefore, larger studies and validation in external cohorts of patients are warranted. In addition, it is an antemortem study, lacking the diagnostic confirmation of brain histopathologic analysis. Finally, although it is beyond the primary scope of this paper, a deeper characterization of CSF-derived EVs with different techniques such as transmission electron microscopy (TEM), would be insightful. However, the enrichment of vesicle fraction by immunocapturing displays an inherent limitation for TEM analysis; in fact, a bead\u2013EV complex might impair the ultrastructural morphological characterization of nanosized vesicles. Nevertheless, we can speculate that at least for plasma-derived EVs, by avoiding ultracentrifugation, which is known to lead to EV deformation and rapture into smaller particles , the morIn conclusion, a diagnostic model based on plasmatic EVs, built via machine learning, integrating information provided by the simultaneous profiling of CSF and plasma could potentially impact on clinical practice. Furthermore, the EV surface markers characterization bolsters the concept of a relevant involvement of inflammation in PD and it underscores the importance of EVs as pathways/biomarkers for protein aggregation-related neurodegenerative diseases."}
{"text": "To reduce patient and procedure identification errors by human interactions in radiotherapy delivery and surgery, a Biometric Automated Patient and Procedure Identification System (BAPPIS) was developed. BAPPIS is a patient identification and treatment procedure verification system using fingerprints.etc. To identify a patient, the BAPPIS reads a fingerprint, identifies the patient, verifies with a second fingerprint to confirm when multiple patients have same fingerprint features, and connects to the patient\u2019s record in electronic medical record (EMR) systems. To validate the system, 143 and 21 patients ranging from 36 to 98 years of ages were recruited from radiotherapy and breast surgery, respectively. The registration process for surgery patients includes an additional module, which has a 3D patient model. A surgeon could mark \u2018O\u2019 on the model and save a snap shot of patient in the preparation room. In the surgery room, a webcam displayed the patient\u2019s real-time image next to the 3D model. This may prevent a possible surgical mistake.The system was developed using C++, the Microsoft Foundation Class Library, the Oracle database system, and a fingerprint scanner. To register a patient, the BAPPIS system requires three steps: capturing a photograph using a web camera for photo identification, taking at least two fingerprints, and recording other specific patient information including name, date of birth, allergies, nd fingerprints from 143 patients as the system designed. A false positive recognition was not reported. The 96.9% completion ratio is because the operator did not verify with another fingerprint after identifying the first fingerprint. The reason may be due to lack of training at the beginning of the study.1,271 (96.9%) of 1,311 fingerprints were verified by BAPPIS using patients\u2019 2We successfully demonstrated the use of BAPPIS to correctly identify and recall patient\u2019s record in EMR. BAPPIS may significantly reduce errors by limiting the number of non-automated steps. Patient identification and procedure verification are well-known problems in the medical industry. The number of serious or even fatal consequences is growing. Accreditation by the Joint Commission demands accuracy of patient identification by using at least two patient identifiers .Unfortunately, the most popular identifier, wristbands, is proving to have an unacceptable error rate. These misidentifications can lead to a medical misadministration and falls under the category of a \u2018sentinel event\u2019. A \u2018sentinel event\u2019 is defined by the Joint Commission as \u201can unexpected occurrence involving death or serious physical or psychological injury, or the risk thereof\u2009\u201d . The senThe Joint Commission analyzed the causes of misadministration in 2005 as illustrated in The \u2018two patient identifiers\u2019 specified by the Joint Commission have a two-fold purpose: firstly, to reliably identify the individual and secondly, to match the service or treatment to that individual. The identifiers may be in the same location, such as a wristband. They must be directly associated with the individual, and the same two identifiers must be directly associated with the treatments or procedure. The \u2018two-identifier\u2019 requirement also applies to an \u2018order for care\u2019 and to report critical test results. Wristband systems are the most common patient identifier in use. These identifiers play an important role in the Joint Commission protocol to reduce surgical misadministration.Effective July 1, 2004, compliance with the Universal Protocol for Preventing Wrong Site, Wrong Procedure, Wrong Person Surgery has been required of all Joint Commission accredited organizations, to the extent that these requirements are relevant to the services provided by the organization . An impoThere are a few competing technologies for patient identification, namely barcode and radio frequency identification (RFID) chips. RFID can be used to track the patient\u2019s location and extract patient information using a remote scanner \u20138. HowevBarcode or RFID chips can be taped on patient wristbands. However, their effectiveness of identifying patients is not convincing. There are two critical studies of the barcoded wristbands, which have a significant pool. The first study was reported by the State University of New York, Downstate Medical Center in Brooklyn, New York . The wriDuring the two years, wristbands were examined 1,757,730 times, and 45,197 wristband errors were found. The mean wristband error rate for the first quarter was 7.4%. However, by the eighth quarter, the mean wristband error rate had fallen to 3.05%. Even with this improvement, sentinel events continued to rise as shown in A second study was conducted at the Veterans Affairs Medical Center in West Los Angeles, California, and compared wristband identification errors for 712 hospitals. Phlebotomists checked 2,463,727 patients\u2019 wristbands, finding 67,289 errors .Ten percent of these hospitals had error rates of 10.9% greater. Patients\u2019 wristbands were missing in 33,308 cases, representing 49.5% of errors. Multiple wristbands with different information occurred 8.3% of the time; wristbands with incomplete data 7.5%; erroneous data 8.6%; illegible data 5.7%; and patients wearing wristbands with another patient\u2019s identifying information occurred 0.5% of the time.We developed a biometric system using fingerprints to meet the Joint Commission\u2019s recommendations and minimize error rates. Our system was designed to interact with Radiology Information System (RIS) and EMR and can potentially eliminate most of the problems associated with wristband systems while helping clinics meet the goals set by the Joint Commission. Patient misidentification is limited to the failure rate of fingerprint identification, which is approximately one out of a billion (provided the patient can offer two fingerprints). Also, procedure verification can be performed biometrically by interacting with the relevant patient database such as an electronic chart or RIS system. Moreover, fingerprints are not subject to loss, damage, or switching between patients in the same way as plastic wristbands. Multiple records for one patient can be prevented since there is one set of unique biometric information , 13. AlsThe project team included a Human Factors Analysis expert to insure the total system (hardware and humans) functions, not just the technical aspects. System design has recently begun to focus on human factors\u2019 considerations. According to Kukula et\u00a0al. , The HumThe successful deployment of biometric systems, regardless of application, needs to take into consideration how individuals interact with the device. Failure to do so will cause a degradation of the optimal performance of the biometric sensor, causing problems such as failure to acquire, failure to enroll, and impacts on the false rejection rate. Moreover, if the individual cannot successfully interact with the biometric device, there is a potential for a failure to function even when the device is implemented.e.g. the patient), the other equally important person in the interaction is the user, the person using the fingerprint biometric device to identify the patient. In fact, the success or failure of the biometric device usually depends on the performance of the user who will provide instructions to the patient and guide the patient through correct finger orientation, force application, and placement in order to acquire a fingerprint sample of sufficient quality for reliable identification. Rood and Jain  cables as illustrated in The hardware consists of personal computers, a database server, optical fingerprint scanners, and web cameras. They are connected The model of the optical fingerprint scanner is SFR300-S (Suprema Inc.). It has a 500 dpi/256 Gy scale optical fingerprint sensor in a plastic case. The scan window is 16\u00a0mm \u00d7 18\u00a0mm. Its physical dimension is 40\u00a0mm (width) \u00d7 77\u00a0mm (length) \u00d7 70.5\u00a0mm (height). Scanning time takes less than a second. The web camera used is an inexpensive CS431 by Intel.\u00ae Visual C++. Each patient\u2019s record in the fingerprint database consists of three components: fingerprint images, a photo image, and a text record. Each scanned fingerprint has key information extracted and stored in a proprietary format  (Our program is written in Microsoftryption) . The phoFingerprint recognition is handled through the UniFinger Engine, a proprietary algorithm provided with the scanner. When we use fingerprint recognition engines, we need to take into account two possible errors. The first one is the false match (FM), and the second one is the false non-match (FNM). The FM refers to the mismatching fingerprints. The FNM is the inability to match a fingerprint to one in the database. These two errors can be adjusted as variables in our system. If the FM rate is set low because false match is a serious security problem, then the fingerprint recognition engine rejects even the tiny mismatch. As a result, the rate of false non-match (rejection) increases. This will translate into more frequent rejections and retries. According to the result of the international fingerprint verification competition in 2006 (FVC2006), the fingerprint recognition algorithm that we are using resulted in a 1.36% FNM rate when FM rate was set to 0%, and a 0.79% FNM rate when the FM rate was set to 0.1%  .We employed two-fingerprint identification step with two different fingers in our system. We set FM rate to 0.1% for the first fingerprint identification to avoid FNM. Then, for the second fingerprint, we verify the identification result by setting FM rate to 0.000001%, so that we can prevent the false positive identification. With two fingerprints, the identification error probability is one out of 100 billion. In single fingerprint mode (using one fingerprint), the error probability is one in 100,000.We also utilize a quality index of the initial fingerprint registration. UniFinger engine provided the fingerprint image quality index in a percentile scale. A good quality fingerprint has distinguishable patterns and features that allow the extraction of features that are useful for subsequent matching of fingerprint pairs. The fingerprint image quality index is a predictor of a pattern recognition algorithm\u2019s performance , and it Our scanner system connects to the fingerprint database using an open-database connectivity (ODBC) driver. ODBC provides a standard method for using database management systems (DBMS). ODBC is designed to be independent of programming languages, database systems, and operating systems . ODBC mae.g., importing a picture to the wrong patient).We felt it was important to make the initial record creation of a patient\u2019s one seamless operation run by a single program. To create a new record, the text information is entered and the patient was photographed with a web camera as displayed in After scanning one finger, the system identifies a patient , and the patient photograph is displayed. Scanning only one finger is an option. A second finger is then scanned to confirm identification. The photograph display is an additional visual check for the patient and staff.We designed the software to interact with other hospital databases using a modular approach. The current module interacts with the radiation oncology Mosaiq , RIS (PACS), and EMR database as shown in etc. A combined fingerprint database was created from both departments, one database from each department. This was designed to prevent duplicate files for a patient.Our project included two departments to test our prototype. For the testing of our prototype system and full clinical study, we acquired an Institutional Review Board (IRB) protocol (CC862) approval. A timing routine was programmed into the software to track the amount of time the user interacted with the software as one measure of functionality and usability. The measurements were saved in log files. The measurements included user logins, fingerprint recognition failures, process durations, All operations with patient information were automatically recorded on encrypted database log files. The files were reviewed once a week by the Principal Investigator. For physical security, the computer database was protected in a locked data server room, while the clinical computers were subject to hospital security measures.For radiation therapy, our system was set up at a receptionist desk and treatment machine console areas to perform two basic tasks: 1) The identification of a patient and entering them into the treatment queue; and 2) The identification of a patient being prepared for treatment and the loading of their treatment settings to the machine. At the receptionist desk, the hardware includes a webcam with a resolution of 640 \u00d7 480, a personal computer, and an optical fingerprint scanner. A receptionist enrolled new patients through the process. When patients returned to the clinic for daily scheduled treatments, they were asked to scan one/two fingers depending on whether the single or two-fingerprint identification mode was being used on the scanner at the reception desk. Our program identified these patients and added them to the waiting list maintained in the Mosaiq system. This process allowed the therapists at the treatment machine to know that the patient had arrived for treatment.When a patient walked into the treatment room, he/she was asked to scan his/her fingers. The photo window was displayed for the therapist to use for visual confirmation of the patient as a second identification after the patient\u2019s fingerprint match. Next, our system retrieved the patient treatment machine settings in the Mosaiq system for their radiotherapy.At each patient visit, after fingerprint(s) were scanned, the system identified and displayed the patient\u2019s photo. It provided the connection to other hospital databases, such as Mosaiq, RIS, and electronic medical record.We installed the BAPPIS system in the UH Cleveland Medical Center Surgery Department where an average of 40 breast surgeries per month are performed in 30 surgical suites. Our systems were installed in two breast consultation suites, one surgery preparation room, one surgery reception desk, and two consultation rooms. Our software provided a module for the surgery department, which allowed a surgeon to create a procedure/orientation verification display consisting of an anatomical sketch, procedure description, and digital image of the patient in treatment position. Once a patient information was recorded in the system, his/her surgeon could create a short surgery description and added an anatomical sketch appropriate to the surgical site from a library, which was available from our software. Most of the information was entered by the surgeon in the consultation room, allowing them to discuss the procedures with the patient. The surgeon clearly marked \u201cyes\u201d on the sketch following the Joint Commission recommendation  for markAt the time of surgery, as the patient entered the surgical suite, his/her fingers were scanned and identified. Once the patient was placed on the surgical couch, a photo was taken and displayed next to the anatomy sketch as illustrated in Once the surgery was completed, the patient file including notes and digital image after surgery was exported to an electronic patient chart and saved in our software system. This eliminated possible confusion during future additional surgeries.A module was designed for adding an authorized user along with their fingerprint to the database. There was a range of privileges that could be assigned to the user based on security requirements and the users\u2019 function. Only privileged users were able to open a patient\u2019s history and modify the patient\u2019s information.We created two clinical fingerprint databases, one for the radiation oncology department and one for the surgery department. The two clinical databases were combined and stored in a node server. This multi-database system could be scaled up to model an entire hospital with multiple satellite clinics.The multi-database architecture used asymmetric cryptography for safe data transfer when communicating between databases. A pair of keys was used to encrypt and decrypt a message and signature so that it was transmitted securely. The communication between fingerprint database servers was therefore confidential and secure, as required by HIPAA , 23. OurAsymmetric cryptography can be illustrated by an example where \u2018John\u2019 wanted to send a fingerprint to \u2018Susie\u2019 securely. A fingerprint was sent to Susie (the remote server) encrypted using Susie\u2019s public-key, and John\u2019s signature (credibility) was included, but encrypted with John\u2019s private-key. John could get Susie\u2019s public key from a public administrator. When Susie got the fingerprint, she decrypted it with her private key, to which no one else should have access. However, she had to verify that it was John who sent the package. John sent his signature encrypted with his private key to Susie who used John\u2019s public key to decrypt his signature. This asymmetric cryptography had been used for internet banking .via network as it dictates the header information to be used for standardized communication when transmitting biometric information (like fingerprints).We also implemented the Common Biometric Exchange Formats Foundation (CBEFF) proposed by the National Institute of Standards and Technology (NIST) . CBEFF wBAPPIS identified 1,311 fingerprints from 143 patients prior to treatment as a graph created in We successfully demonstrated the use of BAPPIS to correctly identify and recall patient plan information using fingerprint identification. BAPPIS could help significantly reduce the number of errors by limiting the number of non-automated steps in the treatment delivery process. The cost of this system is very minimal. A fingerprint scanner\u2019s cost was less than $100, and data server was about $5,000.A significant effort was made toward developing a user-friendly interface . And emphasis was placed on creating a system that patients and professionals could easily use with minimal training. We performed a human factor analysis in every interface during an identification and minimized challenges to the successful operation of the device, such as when handling patients with cognitive or attention limitations, frail elderly patients with loose skin in the fingertips, and patients with vision, hearing, and language difficulties. Every attempt was made to include persons having these characteristics. The inclusion of these patients as test subjects was not subjected to sampling restrictions associated with statistical predictive validity since the total number of subjects was restricted for practical purposes, and the impetus for the testing was not to predict levels of performance in the general population, but rather to identify and eliminate performance problems associated with the device.We opened an IRB protocol and received all participated patients\u2019 consents. We followed HIPAA regulations and recommendations for medical information protection. Our system only stored the identification information  with data encryption. Firewall software was installed on the database server, and security patches were monitored and installed. The patient database only exists within the secure hospital intranet and was never exposed to the internet. Communication between hospitals was through virtual private networks (VPNs). There were few patients who had concerns about taking fingerprints and did not enroll.The comparison between current identification and the use of BAPPIS will be done in the future. Since clinical studies with an IRB required the use of the current identification method by asking name and birthday in addition to BAPPIS, the error rates between two methods were not analyzed.Since we initiated our study, many other biometric systems have been introduced such as fingerprint and vein scanners, palm scanners, and face recognition systems.We successfully demonstrated the use of BAPPIS to correctly identify and recall patient\u2019s record in EMR. BAPPIS may significantly reduce errors by limiting the number of non-automated steps.The original contributions presented in the study are included in the article/supplementary materials; further inquiries can be directed to the corresponding authors.The studies involving human participants were reviewed and approved by Case Western Reserve University and University hospital IRB. The patients/participants provided their written informed consent to participate in this study.JS took charge in the PI and writing of the manuscript. HK and SP developed the system as Co-Inv and wrote the manuscript. SL contributed to the writing of the manuscript. JM and TM were in charge of Co-Inv and writing of the manuscript. TK, MY, CK, SL, RS, and MM participated in the research and writing of the manuscript. All authors contributed to the article and approved the submitted version.The project in this manuscript was supported by an AHRQ 5R18HS017424 GRANT. For this clinical study, an IRB was approved by the University Hospitals of Cleveland and Case Western Reserve University School of Medicine. Case Comprehensive Cancer Center; 5P30CA043703.SP was employed by Cure-In Incorporated. TM was employed by Carlow International Incorporated.The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest."}
{"text": "The potential scarring effects of long-term youth unemployment and social disengagement have for many years challenged policymakers to develop successful and sustainable interventions."}
{"text": "In"}
{"text": "Figs"}
{"text": "Though verification of uninterpreted programs (with no axioms) is already undecidable, a recent work introduced a subclass of coherent uninterpreted programs, and showed that they admit decidable verification\u00a0[We consider the decidability of the verification problem of programs fication\u00a0. We unde"}
{"text": "There is an error in the labels in"}
{"text": "The authors apologize to the readership for any confusion this may have caused."}
{"text": "We have been made aware that a number of figures in the paper cited above  contain We apologize to our readership that this went undetected until now."}
{"text": "PLOS ONE   2] are tXZ and AQ agreed with the retraction. LD, YY, HL, JL, LW, YL, ZD, XJ, HW, ZL, and GZ either did not respond directly or could not be reached. CW did not agree with the retraction."}
{"text": "Furthermore, they apologise to the readership for any inconvenience caused.The authors have re-examined their data and realized that"}
{"text": "The renewal capacity of the heart is extremely limited, with less than 1% cardiomyocyte turnover per year in an adult human heart  is an important factor in regulating cardiomyocyte maturation and cardiomyocyte cell cycle activity  but also achieve complete regeneration of an adult heart."}
{"text": "Correction to: Oncogene10.1038/s41388-018-0495-6Since the publication of this Erratum, the Authors noticed a further error in Fig."}
{"text": "The lecture will be given by the2019 Baltes Award recipient, Allison Bielak, PhD, FGSA, of Colorado State University. The recipient of the2020 Baltes Award is William J. Chopik, PhD. The Margret M. and Paul B. Baltes Foundation Award in Behavioral and Social Gerontology recognizes outstanding early-career contributions in behavioral and social gerontology. The award is generously funded by the Margret M. and Paul B. Baltes Foundation."}
{"text": "The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates."}
{"text": "In"}
{"text": "The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates."}
{"text": "This manuscript has been updated in order to amended incorrect affiliation indices for several authors. The publisher apologies for any confusion caused."}
{"text": "The abstract was originally included twice and this duplication was, unfortunately, not caught by our copy editors. We have removed the duplicated text."}
{"text": "Transthoracic echocardiography revealed large heterogeneous masses adhered to the myocardium with no clear cleavage plane, an intermediate echogenicity and involving the right ventricle, the atrioventricular groove and the large vessels Echocardiographic 2D cine loops Echocardiographic 2D cine loops"}
{"text": "Anshu Bharwaj is now affiliated with CSIR Institute of Microbial technology, Chandiagarh, India. Their updated email address is:"}
{"text": "In each variant of the The approach is robust: it still holds when extending the calculi with operators and extra rules to model some additional computational features."}
{"text": "Cartesian differential categories are categories equipped with a differential combinator which axiomatizes the directional derivative. Important models of Cartesian differential categories include classical differential calculus of smooth functions and categorical models of the differential"}
{"text": "Furthermore, they apologise to the readership for any inconvenience caused.The revised versions of"}
{"text": "The online version has been amended.This paper by Weedon and colleagues (BMJ 2021;372:n214, doi:"}
{"text": "COASTAL is a program analysis tool for Java programs. It combines concolic execution and fuzz testing in a framework with built-in concurrency, allowing the two approaches to cooperate naturally."}
{"text": "This chapter presents the different medical classifications and terminologies as ICD diagnosis codes, SNOMED CT, MeSH, UMLS, ATC etc."}
{"text": "Trypanosoma brucei . It . It M. o"}
{"text": "The last two authors, Ta-Liang Chen and Chien-Chang Liao, should be noted as contributing equally to this work."}
{"text": "In our paper All the authors have read the erratum and agree with the correction."}
{"text": "The following scientists assisted the journal by reviewing manuscripts during the period November 1, 2019 to October 31, 2020.We gratefully acknowledge their critical evaluation and assistance in selecting articles for publication."}
{"text": "In"}
{"text": "In the article titled \u201cLow-Grade Endometrial Stromal Sarcoma with a Nodule-in-Nodule Appearance in Preoperative Magnetic Resonance Images\u201d , there w"}
{"text": "Given the complexity of genetic predisposition to cancer for each individual, implementing an appropriate screening programme for this is simply not feasible at present."}
{"text": "The"}
{"text": "There is an error in"}
{"text": "Wrong:Received: December 24, 2005Right:Received: December 25, 2004"}
{"text": "We believe these issues can be addressed by removing claims of universal scope and adding critical historical and mathematical context to appropriately frame the novelty and scope of this contribution."}
{"text": "In Europe, and elsewhere, it is critical to recognize that this clean energy investment project will pay for itself in full over time in strictly financial terms \u2013 i.e. in addition to its obvious ecological benefits."}
{"text": "The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates."}
{"text": "The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates."}
{"text": "The authors sincerely apologize for this mistake, and regret any inconvenience this mistake has caused.The revised version of"}
{"text": "These have now been added."}
{"text": "In our paper"}
{"text": "It should read \u201cBrewer thioglycolate medium \u201d.The authors regret this error."}
{"text": "The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates."}
{"text": "The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates."}
{"text": "The affiliations for the second and fifth author are incorrect. Filipe C. Serrano and Marcio Martins are not affiliated with #2 but with #3: Departamento de Ecologia, Instituto de Bioci\u00eancias, Universidade de S\u00e3o Paulo, S\u00e3o Paulo, S\u00e3o Paulo, Brazil."}
{"text": "JEM regrets that in the original version of this paper, the x- and y-axes labels in"}
{"text": "The title and caption of Table 12 does not correspond to the table content. The correct title and caption is: \u201cTable 12. Growth chart for fetal femur length/biparietal diameter ratio.\u201dThe title and caption of Table 12 does not correspond to the table content. The correct title and caption is: \u201cTable 13. Growth chart for fetal femur length/head circumference ratio.\u201d"}
{"text": "The first, third, and fourth authors, Jakob D. Wikstrom, Margareta Frohm-Nilsson, and Ada Girnita, should be noted as contributing equally to this work."}
{"text": "The Clark Tibbitts Award lecture will feature an address by the 2020 award recipient, Jan Abusharkrah, PhD, FAGHE. AGHE\u2019s Clark Tibbitts Award was established in 1980 and named for an architect of the field of gerontological education. The award is given each year to an individual or organization that has made an outstanding contribution to the advancement of gerontology and geriatrics education."}
{"text": "Clinical Pharmacology & Safety Sciences, R&D, AstraZeneca, Cambridge, United Kingdom. The correct affiliation is Clinical Pharmacology & Safety Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge, United Kingdom.The authors regret that one affiliation address is mistaken in the published paper. Matthew Bridgland-Taylor's affiliation was incorrectly listed as The authors would like to apologise for any inconvenience caused."}
{"text": "The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates."}
{"text": "The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates."}
{"text": "The caption for"}
{"text": "The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates."}
{"text": "The Editor has retracted this article  because Authors Chuncheng Zhang, Jing Yue, Mingyue Li, Wei Jiang, Yu Pan, Zhimin Song, Cailian Shi, Weixuan Fan and Zhenxiang Pan all agree to this retraction."}
{"text": "The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates."}
{"text": "The authors have retracted this poster abstract  because All authors agree to this retraction."}
{"text": "Furthermore, they apologize to the readership for any inconvenience caused.The authors have re-examined their data and realized that"}
{"text": "The labelling on the x-axis in"}
{"text": "The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates."}
{"text": "The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates."}
{"text": "The authors sincerely apologize for this mistake, and regret any inconvenience this mistake has caused.The revised version of"}
{"text": "The revised version of"}
{"text": "In"}
{"text": "The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates."}
{"text": "We appreciate Zins and Abraham  commenti"}
{"text": "Due to an error during production and a corrupted data set, Importantly, these changes do not modify the significance and the related conclusions in any way. The authors would like to apologize for any inconvenience to the readers caused by this error.As depicted in"}
{"text": "The authors wish to add funding project UIDB/00100/2020 into the Funding section of this paper ["}
{"text": "The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates."}
{"text": "In this paper, we present MachSMT, an algorithm selection tool for Satisfiability Modulo Theories (SMT) solvers. MachSMT supports the entirety of the SMT-LIB language. It employs machine learning (ML) methods to construct both empirical hardness models (EHMs) and pairwise ranking comparators (PWCs) over state-of-the-art SMT solvers. Given an SMT formula"}
{"text": "The online version has been amended.In this paper by Harriet Forbes and colleagues (BMJ 2021;372:n628, doi:"}
{"text": "In"}
{"text": "The Irving S. Wright Award of Distinction Lecture will feature an address by the 2020 recipient James L. Kirkland, MD, PhD. This award is given by the American Federation for Aging Research, Inc."}
{"text": "A recent paper  comparedA recent review on ML methods in a clinical epidemiological context shows that benefits of ML tend to arise in biased comparisons . In the"}
{"text": "NUT\u764c\u662f\u4ee5\u67d3\u8272\u4f5315q14\u4e0a\u777e\u4e38\u6838\u86cb\u767d\uff08nuclear protein in testis, NUTM1\uff09\u91cd\u6392\u4e3a\u7279\u5f81\u7684\u4e00\u79cd\u7f55\u89c1\u7684\u6076\u6027\u7a0b\u5ea6\u6781\u9ad8\u7684\u80bf\u7624\uff0c\u5176\u53d1\u75c5\u673a\u5236\u53ca\u6cbb\u7597\u65b9\u6cd5\u76ee\u524d\u5c1a\u4e0d\u660e\u786e\uff0c\u5176\u9884\u540e\u6781\u5dee\u3002\u56e0\u5176\u597d\u53d1\u90e8\u4f4d\u4e3b\u8981\u96c6\u4e2d\u5728\u8eaf\u4f53\u4e2d\u7ebf\u4f4d\u7f6e\uff0c\u5982\u773c\u7736\u3001\u9f3b\u8154\u3001\u4e0a\u989a\u3001\u7eb5\u9694\u7b49\uff0c\u6545\u53c8\u79f0\u4e3a\u4e2d\u7ebf\u764c\u3002\u56db\u5ddd\u5927\u5b66\u534e\u897f\u533b\u9662\u80f8\u90e8\u80bf\u7624\u79d1\u6536\u6cbb\u4e861\u4f8b\u80baNUT\u764c\u60a3\u8005\uff0c\u4e3a70\u5c81\u8001\u5e74\u7537\u6027\uff0c\u521d\u8bca\u4e3a\u4f53\u68c0\u53d1\u73b0\u5de6\u80ba\u95e8\u5360\u4f4d\uff0c\u672f\u540e\u75c5\u7406\u63d0\u793a\u4f4e\u5206\u5316\u764c\uff0c\u7ecf\u8367\u5149\u6807\u8bb0\u7684\u539f\u4f4d\u6742\u4ea4\u6280\u672f\u8bc1\u5b9e\u4e3aNUT\u764c\uff0c\u672f\u540e\u7ecf\u5316\u7597\u3001\u6297\u8840\u7ba1\u6cbb\u7597\u3001\u653e\u7597\u7b49\u7efc\u5408\u6cbb\u7597\u83b7\u5f97\u4e86\u8f83\u957f\u7684\u751f\u5b58\u671f\u3002\u672c\u6587\u7ed3\u5408\u6587\u732e\u56de\u987e\u62a5\u544a\u4e86\u80baNUT\u764c\u8fd9\u4e00\u5c11\u89c1\u5b9e\u4f53\u7624\u7684\u4e34\u5e8a\u3001\u75c5\u7406\u7279\u5f81\u53ca\u6cbb\u7597\u7b56\u7565\u3002"}
{"text": "In"}
{"text": "In the Data Deposition section of the Material and Methods, there is an error in the seventh sentence. The sentence should read: sRNA-seq of AGO1 IP and AGO10 IP from AGO10 OE (three replicates)."}
{"text": "China*Contributed equallyThe authors regret their oversight in this regard, and apologize for any inconvenience caused."}
{"text": "Drs. Low and Turner for their thoughtful comments on our paper [We would like to thank ur paper  and theiur paper \u20134 (\u201cthreur paper , althougur paper \u20139. Howevur paper  without ur paper . This isur paper . Low andur paper , which iur paper . We shou"}
{"text": "The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates."}
{"text": "Europe has a window of opportunity to embark on a recovery that tilts towards digitalisation and a greener economy, and stands to generate sustainable benefits for its people."}
{"text": "Early assessment of diffusion and possible expansion of SARS-CoV-2 Lineage 20I/501Y.V1  in France, January to March 2021\u2019 by Gaymard et al., published on 4 March 2021, a recognition of the laboratories belonging to the ColVHB network was added to the Acknowledgements section. This change was made on request of the authors on 5 March 2021.In the article \u2018"}
{"text": "The first three authors, Timo Tondelli, Tobias G\u00f6tschi, and Roland S. Camenzind, should be noted as contributing equally to this work. The publisher apologizes for the error."}
{"text": "We consider parameterized concurrent systems consisting of a finite but unknown number of components, obtained by replicating a given set of finite state automata."}
{"text": "In,"}
{"text": "The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates."}
{"text": "Wrong:Received: December 24, 2005Right:Received: December 25, 2004"}
{"text": "The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates."}
{"text": "The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates."}
{"text": "This report describes the 2020 Competition on Software Verification (SV-COMP), the 9"}
{"text": "The captions for Figs"}
{"text": "This abstract contained reference to the drug \u2018azithromycin\u2019 where \u2018aztreonam\u2019 should have been stated.The authors apologise for any inconvenience."}
{"text": "Keynote at the 20th European Conference on Eye Movement Research (ECEM) in Alicante, 20.8.2019.Video stream:https://vimeo.com/357889739"}
{"text": "We provide graded extensions of algebraic theories and Lawvere theories that correspond to graded monads. We prove that graded algebraic theories, graded Lawvere theories, and finitary graded monads are equivalent via equivalence of categories, which extends the equivalence for monads. We also give sums and tensor products of graded algebraic theories to combine computational effects as an example of importing techniques based on algebraic theories to graded monads."}
{"text": "Cross-cultural validation of the FACE-Q Satisfaction with Facial Appearance Overall Scale (FACE-Q SFAOS) in Brazilian rhytidoplasty patientsIn the article Replace"}
{"text": "In the article titled \u201cCaffeine's Vascular Mechanisms of Action\u201d , there w\u201cCaffeine metabolism yields paraxanthine as a final product, which represents 72 to 80% of caffeine metabolism. There are five main metabolic pathways which contribute to caffeine metabolism in adults . The first three consist of demethylization of N-3 to form Paraxanthine, N-1 to form Theophylline , and N-7 to form Theophylline .\u201dAccordingly, the paragraph should read as follows:\u201cCaffeine metabolism yields paraxanthine as a final product, which represents 72 to 80% of caffeine metabolism. There are five main metabolic pathways which contribute to caffeine metabolism in adults . The first three consist of demethylization of N-3 to form Paraxanthine, N-1 to form Theobromine , and N-7 to form Theophylline .\u201d"}
{"text": "Sooner or later, the ECB must accept that monetary financing in support of deficit spending is a necessity not just for mitigating the coronavirus crisis, but also for averting a downward deflationary cycle that could pull the eurozone apart."}
{"text": "In our paper"}
{"text": "The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates."}
{"text": "Munidopsis lauensis and M. verrilli: Novel gene arrangements and phylogenetic implications\u201d, which was published in volume 9 issue 22, November In \u201cThe complete mitochondrial genomes of two vent squat lobsters, M. lauensis and M. verrilli, were captured from a hydrothermal vent chimney at a depth of 1374 m  in the northwest Pacific Ocean.The hydrothermal vent squat lobsters,"}
{"text": "Minthostachys mollis: A Medicinal Plant Commonly Used in the Traditional Andean Medicine in Peru\u201d [In the article titled \u201cPotential Toxicity of the Essential Oil from in Peru\u201d , there w"}
{"text": "The authors regret the use of incorrect panels in Fig.\u00a05 B1) and Fig.\u00a06  of their publication [ and Fig.The corrected Figs."}
{"text": "The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates."}
{"text": "Figs"}
{"text": "In"}
{"text": "This article originally contained the following statement in reference to ZELNORM (tegaserod): \"It is not prescribed in the USA.\"However, on August 15, 2019, ZELNORM (tegaserod) was reintroduced to the United States market. Therefore, the text has been amended to reflect that\u00a0ZELNORM (tegaserod) is indeed currently prescribed in the USA. The authors and Cureus sincerely regret the error."}
{"text": "The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates."}
{"text": "The Donald P. Kent Award lecture will feature an address by the 2019 Kent Award recipient, Terry Fulmer, PhD, of The John A. Hartford Foundation. The Kent Award is given annually to a member of The Gerontological Society of America who best exemplifies the highest standards of professional leadership in gerontology through teaching, service, and interpretation of gerontology to the larger society. The Robert W. Kleemeier Award lecture will feature an address by the 2019 Kleemeier Award recipient, Steven Zarit of Pennsylvania State University. The Kleemeier Award is given annually to a member of The Gerontological Society of America in recognition for outstanding research in the field of gerontology"}
{"text": "The fifth author, T. N. C. Ramya, was incorrectly attributed equal contribution to this work with Kamaldeep Kaur, Indu Khatri, and Akil Akhtar. Only the first three authors, Kamaldeep Kaur, Indu Khatri, and Akil Akhtar, should be noted as contributing equally to this work. The publisher apologizes for the error."}
{"text": "Epidemiology & Infection with the indication that A. Pich\u00f3n Riviere's surname should be indexed as \u2018Riviere, AP\u2019 instead of \u2018Pich\u00f3n Riviere, A.\u2019 and was originally published as such.The above paper was originally submitted to This has been rectified in the online PDF and HTML copies and re-indexed accordingly."}
{"text": "The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates."}
{"text": "The authors wish to make the following erratum in this paper .Research Center for Eco-Environment Sciences, Chinese Academy of Sciences, Beijing 100085, China; ljbao_st@rcees.ac.cn (L.B.); dretfr456@gmail.com (W.C.); chenhao@rcees.ac.cn (H.C.); yswei@rcees.ac.cn (Y.W.)College of Resources and Environment, University of Chinese Academy of Science, Beijing, 100049, ChinaThere are mistakes in the spelling of the first and second institute names of the authors:Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China; ljbao_st@rcees.ac.cn (L.B.); dretfr456@gmail.com (W.C.); chenhao@rcees.ac.cn (H.C.); yswei@rcees.ac.cn (Y.W.)College of Resources and Environment, University of Chinese Academy of Sciences, Beijing, 100049, ChinaThe corrected spelling should be:The authors apologize for any inconvenience this may have caused."}
{"text": "In the Funding statement, the RSP number from the funder Researchers Supporting Project, King Saud University, Riyadh, Saudi Arabia is listed incorrectly. The correct RSP number is: RSP-2020/194."}
{"text": "The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates."}
{"text": "EML4-ALK)\u878d\u5408\u5360\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u60a3\u8005\u76843%-5%\u3002\u968f\u7740\u5bf9\u8be5\u9a71\u52a8\u57fa\u56e0\u7684\u6df1\u5165\u7814\u7a76\uff0c\u4ee5Crizotinib\u4e3a\u4ee3\u8868\u7684ALK\u6291\u5236\u5242\u9010\u6e10\u88ab\u5f00\u53d1\u5e76\u5e94\u7528\u4e8e\u4e34\u5e8a\u3002\u7136\u800c\uff0c\u4e0d\u540c\u60a3\u8005\u5bf9ALK\u9776\u5411\u6cbb\u7597\u7684\u53cd\u5e94\u5b58\u5728\u5dee\u5f02\uff0c\u4e14\u591a\u6570ALK\u9776\u5411\u6cbb\u7597\u60a3\u8005\u6700\u7ec8\u4f1a\u4e0d\u53ef\u907f\u514d\u5730\u51fa\u73b0\u8010\u836f\uff0c\u5bfc\u81f4\u80bf\u7624\u8fdb\u5c55\u3002\u5229\u7528\u9884\u540e\u6807\u5fd7\u7269\u76d1\u6d4b\u60a3\u8005\u7597\u6548\u53ca\u65f6\u6539\u53d8\u6cbb\u7597\u65b9\u6848\uff0c\u4ee5\u53ca\u6839\u636e\u8010\u836f\u673a\u5236\u9009\u62e9\u4e2a\u4f53\u5316\u7684\u540e\u7eed\u6cbb\u7597\uff0c\u53ef\u4ee5\u6709\u6548\u5730\u6539\u5584\u60a3\u8005\u7684\u9884\u540e\u3002\u672c\u6587\u5c06\u5bf9ALK\u6291\u5236\u5242\u7684\u8010\u836f\u673a\u5236\u4ee5\u53ca\u76f8\u5173\u7684\u9884\u540e\u6807\u5fd7\u7269\u5c55\u5f00\u7efc\u8ff0\uff0c\u63a2\u8ba8ALK\u9776\u5411\u6cbb\u7597\u7597\u6548\u9884\u6d4b\u4ee5\u53ca\u8010\u836f\u60a3\u8005\u540e\u7eed\u6cbb\u7597\u65b9\u6848\u7684\u9009\u62e9\u3002\u68d8\u76ae\u52a8\u7269\u5fae\u7ba1\u76f8\u5173\u7c7b\u86cb\u767d4-\u95f4\u53d8\u6027\u6dcb\u5df4\u7624\u6fc0\u9176(echinoderm microtubule-associated protein like 4-anaplastic lymphoma kinase,"}
{"text": "We focus on the large central charge sector of the 3 with the corresponding cutoff surface, given a holographic dictionary which identifies gravity parameters with In this article we probe the proposed holographic duality between"}
{"text": "The following correction has been made to this paper : We woul"}
{"text": "Trichosanthes tricuspidata Lour. Methanol Extract Exhibits Anti-Inflammatory Activity by Targeting Syk, Src, and IRAK1 Kinase Activity\u201d [In the article titled \u201cctivity\u201d . The aut"}
{"text": "Furthermore, they apologize to the readership for any inconvenience caused.The authors regret the error that was made in the preparation of the published figure, and confirm that this error did not affect the conclusions reported in the study. The authors are grateful to the editor of"}
{"text": "Social distancing restrictions, as measured by the Oxford stringency indicator, constitute the one variable that is most tightly correlated with the recession and recovery across EU member states."}
{"text": "It has the traditional advantage that algorithms for branching bisimilarity are more efficient than ones for other weak behavioural equivalences, especially weak bisimilarity. With lgorithm\u00a0, resulti"}
{"text": "CDO1\u4f5c\u4e3a\u6291\u764c\u57fa\u56e0\u5e38\u5728\u80bf\u7624\u53d1\u751f\u65e9\u671f\u4fbf\u4f1a\u53d1\u751f\u7532\u57fa\u5316\u6539\u53d8, \u56e0\u6b64\u672c\u7814\u7a76\u65e8\u5728\u63a2\u8ba8CDO1\u7532\u57fa\u5316\u5728\u80ba\u764c\u65e9\u671f\u8bca\u65ad\u4e2d\u7684\u4ef7\u503c\u3002\u80ba\u764c\u7684\u53d1\u751f\u7387\u548c\u6b7b\u4ea1\u7387\u5e38\u5c45\u6240\u6709\u6076\u6027\u80bf\u7624\u7684\u9996\u4f4d, DNA\u7532\u57fa\u5316\u4f5c\u4e3a\u8868\u89c2\u9057\u4f20\u5b66\u4e4b\u4e00\u53c2\u4e0e\u80bf\u7624\u7684\u53d1\u751f\u53d1\u5c55\u8fc7\u7a0b, \u6536\u96c6\u80bf\u7624\u60a3\u8005\u548c\u5065\u5eb7\u4eba\u7fa4\u7684\u5916\u5468\u8840\u6db2\u6837\u672c, \u6e38\u79bbDNA\u901a\u8fc7\u4e9a\u786b\u9178\u76d0\u4fee\u9970\u5e76\u7ed3\u5408\u5b9e\u65f6\u8367\u5149\u5b9a\u91cfPCR\u68c0\u6d4bCDO1\u5728\u5916\u5468\u8840\u4e2d\u7684\u7532\u57fa\u5316\u6c34\u5e73\u3002CDO1\u7684\u7532\u57fa\u5316\u6c34\u5e73\u5728\u6027\u522b\u3001\u6dcb\u5df4\u7ed3\u8f6c\u79fb\u548c\u80bf\u7624\u539f\u53d1\u7076-\u6dcb\u5df4\u7ed3-\u8f6c\u79fb\u5206\u671f\u7684\u5206\u5c42\u6bd4\u8f83\u4e2d\u5b58\u5728\u663e\u8457\u6027\u5dee\u5f02(P < 0.05)\u3002CDO1\u5bf9\u80ba\u764c\u8bca\u65ad\u7684\u7075\u654f\u5ea6\u548c\u7279\u5f02\u6027\u5206\u522b\u4e3a52.2%\u548c78.6%\u3002\u5176\u8bca\u65ad\u7684\u6574\u4f53\u51c6\u786e\u5ea6\u660e\u663e\u9ad8\u4e8e\u5e94\u7528\u4e8e\u4e34\u5e8a\u7684\u80bf\u7624\u6807\u5fd7\u7269\u800c\u4e14\u5bf9I\u671f\u3001II\u671f\u60a3\u8005\u7684\u8bca\u65ad\u7075\u654f\u5ea6\u8868\u73b0\u6700\u597d\u3002\u6b64\u5916, CDO1\u53ef\u6709\u6548\u589e\u52a0\u591a\u9879\u8054\u68c0\u4e2d\u8bca\u65ad\u7684\u7075\u654f\u6027\u3002\u80ba\u764c\u60a3\u8005\u7684\u5916\u5468\u8840\u7684\u57fa\u56e0\u7532\u57fa\u5316\u6c34\u5e73\u660e\u663e\u9ad8\u4e8e\u80ba\u90e8\u826f\u6027\u75be\u75c5\u60a3\u8005\u53ca\u5065\u5eb7\u4eba\u7fa4\u3002\u80ba\u764c\u60a3\u8005CDO1\u7684\u7532\u57fa\u5316\u6c34\u5e73\u5bf9\u80ba\u764c\u7684\u65e9\u671f\u8bca\u65ad\u5177\u6709\u6f5c\u5728\u7684\u5de8\u5927\u4f18\u52bf\u3002\u68c0\u6d4b"}
{"text": "Acta Cryst. (2020), E76, 742\u2013746.Corrigendum to  Acta Cryst. (2020), E76, 742\u2013746], there is an error in the chemical names of the title compounds.In the paper by Sugiyama [ Abstract are correct.The chemical names of the title compounds in the paper by Sugiyama 2012 are inco"}
{"text": "Figs"}
{"text": "The authors of \u201cTowards a cancer mission in Horizon Europe: recommendations\u201d : 1589\u20101615. PMID: 32749074) ["}
{"text": "On 2 April 2020, the European Commission (2020) duly put forward a proposal for the creation of a European instrument for temporary Support to mitigate Unemployment Risks in an Emergency (SURE). This bold and innovative move must be welcome, but the actual profile of this new instrument requires clarification to avoid misunderstandings, false expectations and eventual disappointment."}
{"text": "The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates."}
{"text": "It has been brought to our attention that the methods and results presented in  are almoSensors.MDPI is a member of the Committee on Publication Ethics and takes seriously its responsibility to publish only high-quality research. We regret that this was not discovered prior to publication and offer our apologies to the readers of"}
{"text": "Keynote at the 20th European Conference on Eye Movement Research (ECEM) in Alicante, 22.8.2019Video stream:https://vimeo.com/361729502"}
{"text": "The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates."}
{"text": "In Figs"}
{"text": "In the original publication the photo of the gregarious adult locust in Fig."}
{"text": "In"}
{"text": "The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates."}
{"text": "The authors regret that original paper was published with errors in Table\u00a02. The number of men have been switched. Correct values areMenNonobese n\u00a0=\u00a0163,Obese n\u00a0=\u00a089.The authors apologies for any inconvenience caused."}
{"text": "The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates."}
{"text": "In"}
{"text": "The Joseph T. Freeman Award lecture will feature an address by the2020 Freeman Award recipient Cynthia Brown, MD, MSPH. The Joseph T. Freeman Award is a lectureship in geriatrics awarded to a prominent physician in the field of aging, both in research and practice. The award was established in1977 through a bequest from a patient\u2019s estate as a tribute to Dr. Joseph T. Freeman."}
{"text": "The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates."}
{"text": "The COVID-19 pandemic carries heavy threats, and preserving stable and coordinated international trade relations will be essential to avoid catastrophic disorders or conflicts."}
{"text": "Although austerity was particularly strong in the aftermath of the economic crisis of 2008 and its consequences in the euro area, Italian fiscal policies have been characterised by tough consolidation periods ever since the 1990s."}
{"text": "We extend the"}
{"text": "Due to a technical error with the Cureus software, all instances of P-values measuring \"< .0001\" were erroneously omitted from Tables 1-3. These p-values have been restored to the tables. Cureus sincerely regrets the technical and editorial errors that led to this article being published without the p-values."}
{"text": "There is an error in the footnote of"}
{"text": "Keynote by Enkelejda Kasneci at the 20th European Conference on Eye Movement Research (ECEM) in Alicante, 18.8.2019,Video stream of presentation: https://vimeo.com/356314274"}
{"text": "It was highlighted that the original article  containeIncorrectThe returned similarity score is based on Jaccard similarity [18] of Morgan-style connectivity fingerprints [19] with a radius of up to 5.CorrectThe returned similarity score is based on Jaccard similarity [18] of Morgan-style connectivity fingerprints [19] with a radius of up to 3."}
{"text": "Therefore, we\u2019d like to declare a correction to the authorship that Prof. Ma is listed as one of the corresponding authors."}
{"text": "The revised version of"}
{"text": "An investigation was conducted in accordance with Frontiers guidelines and the authors failed to provide a satisfactory explanation.This retraction was approved by the Chief Editors of Frontiers in Oncology and the Editor-in-Chief of Frontiers. The authors agree to this retraction."}
{"text": "The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates."}
{"text": "Supplement 1 published in Volume 20 of BMC Plant Biology contained several incorrect 'received dates'"}
{"text": "Medicine has published two,2 articles with protocol mistakenly added to the title. The titles have been updated to remove this.In recent issues,"}
{"text": "A toolkit of tagged glp-1 alleles reveals strong glp-1 expression in the germline, embryo, and spermatheca. microPublication Biology. The authors correct the following:JK5525 glp-1(q46) III; qSi155[Cbr-unc-119 + glp-1::Halotag] IV\u2019is corrected to\u2018JK5225 glp-1(q46) III; qSi155[Cbr-unc-119 + glp-1::Halotag] IV\u2019In the Methods section:The strain\u2018JK5526 glp-1(q46) III; qSi156[Cbr-unc-119 + glp-1::Halotag] IV\u2019is corrected to\u2018JK5226 glp-1(q46) III; qSi156[Cbr-unc-119 + glp-1::Halotag] IV\u2019The strain\u2018Throughout the text and in the Methods section:3xOLLAS]\u201dis corrected to:\u201c[glp-1::2xOLLAS]\u201dThe genotype of strain JK5973\u201c[glp-1::"}
{"text": "It has been brought to our attention that this paper  was susp"}
{"text": "The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates."}
{"text": "In In"}
{"text": "The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates."}
{"text": "In our paper"}
{"text": "The affiliations for the first author are incorrect. Minlu Li is not affiliated with both #1 and #2, but #1 only: General Ward of Neurology, West China Hospital/ West China School of Nursing, Sichuan University, Chengdu, Sichuan, China."}
{"text": "The authors regret that the funding information given in the original manuscript was incorrectly shown. The authors declare that there was no financial support for this research.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates."}
{"text": "With distinct levels of completeness and capabilities to model different developmental stages, embryo models offer an experimental platform for To view this SnapShot, open or download the PDF."}
{"text": "The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates."}
{"text": "In our paper"}
{"text": "The online version of the \u201cClinico-radiological Observations in Meconium Aspiration Syndrome\u201d:510\u20135) has been updated according to the letter to the editor and respective authors' reply published in JNMA 213 Issue."}
{"text": "In"}
{"text": "The authors would like to make the following corrections to the published paper .Replacing the Institutional Review Board number 2019800990B0 with 201800990B0."}
{"text": "The authors should be congratulated on reporting their findings in a large radical cystectomy cohort for muscle-invasive (MIBC) and metastatic bladder cancer . The man"}
{"text": "The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates."}
{"text": "Sci., 2021, DOI: 10.1039/d1sc00001b.Correction for \u2018Mechanochemical generation of acid-degradable poly(enol ether)s\u2019 by Jinghui Yang  The authors regret an error in The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "In our paper"}
{"text": "TED\u2019 by Yuka Kobayashi et al., Chem. Sci., 2020, DOI: 10.1039/d0sc03521a.Correction for \u2018Crystal structure and metallization mechanism of the \u03c0-radical metal  The authors regret an error in The correction of The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "There is an error in the affiliation for authors Stephane Perrey and Makii Muthalib. The correct affiliation is: EuroMov Digital Health in Motion, Univ Montpellier, IMT Mines Ales, Montpellier, France."}
{"text": "The corrected list of affiliations is as shown here.The authors regret that the one of the affiliations (affiliation The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "In"}
{"text": "The journal is issuing this expression of concern to alert readers to significant concerns regarding the paper cited above .Serious concerns have been raised about misinterpretation of the data and the conclusions.The major concern is the misrepresentation of the COVID-19 vaccination efforts and misrepresentation of the data, e.g., Abstract: \u201cFor three deaths prevented by vaccination we have to accept two inflicted by vaccination\u201d. Stating that these deaths linked to vaccination efforts is incorrect and distorted.We will provide an update following the conclusion of our investigation. The authors have been notified about this Expression of Concern."}
{"text": "The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates."}
{"text": "The hazard ratio label on the first line of"}
{"text": "In the original publication  there waNone.Taishan Scholars Program of Shandong Province (NO.ts 20190982)."}
{"text": "The authors of  would li"}
{"text": "Italy\u2019s economy is not expected to return to pre-pandemic levels before the first half of 2023, and an early return to budgetary constraints would be disastrous."}
{"text": "Following the publication of the original article , we wereCorrected units are represents in Bold:Table 2109/L)WBC (1012/L)RBC (HGB (g/L)HCT (L/L)MCV (fL)MCHC (g/L)RDW (%)109/L)PLT (109/L)Neutrophils (109/L)Lymphocytes (109/L)Monocytes (109/L)Eosinophils (109/L)Basophils (Table 3(nmol/L)Total T4"}
{"text": "Furthermore, they regret that these errors were introduced into the paper, even though they did not substantially alter any of the major conclusions reported in the paper, and apologize to the readership for any inconvenience caused.The corrected versions of"}
{"text": "Page 1, line 23: \u201c>3 kb\u201d should read \u201c<3 kb.\u201dVolume 10, no. 39, e00715-21, 2021,"}
{"text": "The first sentence, \u201cThe United Nations Humanitarian Commission for Refugees (UNHCR)\u201d should say \u201cUnited Nations High Commissioner for Refugees (UNCHR)\u201d.In the original publication,The author apologises for this error."}
{"text": "Hortae werneckii, which occurs mainly in tropical and subtropical regionsTinea nigra is a rare, chronic, asymptomatic, and superficial keratophytosis caused by the dematiaceous fungus"}
{"text": "There is an error in"}
{"text": "In"}
{"text": "The authors regret errors in Fig.\u00a0Fig. 2 TEM (a) and HRTEM (b) images of FMSPs. d Magnetic curve of FMSPs. g PL emission and excitation spectra of FMSPs"}
{"text": "After having been in contact with the authors, they agreed with the decision to retract the paper. The Editor apologizes to the readership for any inconvenience caused."}
{"text": "Bioscience Reports at the request of the authors following receipt of a notification from a reader, alerting the Editorial Office to the data in Figures 5A and 5C as well as the Western blots in Figures 1C and 6B.This article is being retracted from The Editorial Office contacted the authors to request the raw data and raw images of the Western blots, to which the authors responded with the Retraction request stating that the integrity of the research was damaged. Given the concerns raised the Editor-in-Chief and Editorial Board agree with the Retraction. The co-corresponding author Huang-Shan wishes to take full responsibility for their negligence, and apologizes for the inconvenience caused to the journal and readers."}
{"text": "In the original publication, the authors contributing equally to this paper was not presented clear.The corrected text is given below:Jian-Jun Zhao and Song-Yu Li have contributed equally to this work."}
{"text": "In Tables"}
{"text": "CLINICS (Sao Paulo). 2021;76:e2914errhttps://doi.org/10.6061/clinics/2021/e2914, published in 2021.Erratum for: doi: Expression of Amphiregulin in Enchondromas and Central Chondrosarcomas, RESULTS section in the Abstract, remove the following sentences:In the article \u201cEnchondromas or chondrosarcomas? Please clarify. This will help understand the next sentence on enchondromas localized in short bones and long bones.\u201d"}
{"text": "To the editor,We appreciate very much your comment about our paper published recently in Int Braz J Urol . In respThe Authors"}
{"text": "The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates."}
{"text": "The Editorial Office has been made aware of potential issues surrounding the scientificvalidity of this paper, hence has issued an expression of concern to notify readerswhilst the Editorial Office investigates."}
{"text": "In our paper"}
{"text": "The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates."}
{"text": "The correct affiliations are listed in this correction notice.The authors regret that affiliation The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Sci., 2019, 10, 10524\u201310530, DOI: 10.1039/C9SC03829A.Correction for \u2018A hybrid blue perovskite@metal\u2013organic gel (MOG) nanocomposite: simultaneous improvement of luminescence and stability\u2019 by Samraj Mollick  The formula should read EA2PbBr4.The authors regret that the formula used for the 2D perovskite EAPbBrThe Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "There is an error in the caption of"}
{"text": "Erratum zu:Bundesgesundheitsbl 202110.1007/s00103-021-03396-9In der urspr\u00fcnglichen Originalfassung des Artikels wurden einige Namen der Autorinnen und Autoren nicht korrekt wiedergegeben.Die Namen wurden nun korrigiert."}
{"text": "In this paper, the phrases should be corrected as follows:4. Desmoceras (D.) japonicum Yabe.1)\u201dFor \u201c4. Desmoceras (P.) japonicum Yabe.1)\u201d.read \u201c5. Desmoceras ezoanum Matsumoto.\u201dFor \u201c5. Desmoceras (P.) ezoanum Matsumoto.\u201d.read \u201c"}
{"text": "In"}
{"text": "In the original publication, the section \u201cAcknowledgments\u201d is not be included. The Acknowledgments section is given in in this correction.Acknowledgments This research was partly supported by AMED under Grant Number JP18ck0106463."}
{"text": "Across the board statements on who suffers most are not helpful and may actually be a disservice to the fight for greater gender equality."}
{"text": "It should instead read\u2009\u2212\u20095.94 .The authors found\u00a0two\u00a0minor errors in the text, abstract and Table 2:"}
{"text": "Too much blood in terms of unemployment and sweat in terms of intellectual effort has been spent on trying to determine the amount of fiscal space that economies have \u2014 our policy focus instead should be on what to do with the fiscal space that almost all advanced economies (and a surprising number of emerging market economies) actually have."}
{"text": "In our paper"}
{"text": "Endocanin 22.1% . Those c"}
{"text": "The Editorial Office has been made aware of potential issues surrounding the scientificvalidity of this paper, hence has issued an expression of concern to notify readerswhilst the Editorial Office investigates."}
{"text": "N/A C.iwatai was collected from Yunnan: Baoshan, instead of Yunnan: Menglian Dai; C.kaihuanus was collected from Yunnan: Jinghong, instead of Yunnan: Guangnan county; and C.filippovi was collected from Sichuan: Mount Emei, instead of Sichuan: Emeishan city.It has come to our attention that in the work referenced above, Figure"}
{"text": "Second EDN3-OE \u2019.Molecular Medicine Reports for granting them the opportunity to publish this. The authors regret that these errors were included in the paper, and also apologize to the readership for any inconvenience caused.All the authors approve of the publication of this corrigendum, and the authors are grateful to the Editor of"}
{"text": "Changes of immune cells in patients with hepatocellular carcinoma treated by radiofrequency ablation and hepatectomy, a pilot study. Open Life Sci. 2021;16(1):1002\u20139. The authors apologize to the Journal, readers, and their colleagues for the mistake and any inconvenience it caused."}
{"text": "To the editor,We thank the comments made by Dr. Atan regarding our manuscript \u201cImpact of COVID-19 pandemic on a urology residency program\u201d , 3. ThesThe Authors"}
{"text": "N- and N,N\u2032-alkyl indigo derivatives\u2019 by Daniela Pinheiro et al., Chem. Sci., 2020, DOI: 10.1039/d0sc04958a.Correction for \u2018Deep in blue with green chemistry: influence of solvent and chain length on the behaviour of  The authors regret that incorrect compound names and values are reported in The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates."}
{"text": "The caption for"}
{"text": "The Donald P. Kent Award lecture will feature an address by the 2020 Kent Award recipient, David Ekerdt, PhD, FGSA, of the University of Kansas. The Kent Award is given annually to a member of The Gerontological Society of America who best exemplifies the highest standards of professional leadership in gerontology through teaching, service, and interpretation of gerontology to the larger society. The Robert W. Kleemeier Award lecture will feature an address by the 2020 Kleemeier Award recipient, Matt Kaeberlein, PhD, FGSA, of the University of Washington. The Kleemeier Award is given annually to a member of The Gerontological Society of America in recognition for outstanding research in the field of gerontology."}
{"text": "The authors wish to make the following corrections to this paper . In the Dr. SangJoon Lee has been requested by Ulsan National Institutes of Science and Technology (UNIST) that his affiliation of UNIST be removed from the Affiliations, because Dr. Lee\u2019s position was not officially assigned by UNIST when the paper was published.2: Department of Infection Biology, Faculty of Medicine, University of Tsukuba, Ibaraki 305-8577, Japan. The corrected affiliation section should be: SangJoon LeeThe authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. The original publication has also been updated."}
{"text": "Following the publication of this paper, the authors have realized that they overlooked indicating that Zhikun Chen and Qin Che contributed equally to this work. Therefore, the affiliations for this paper should have been written as follows:1*, QIN CHE2* and CHUNXUE XIE3ZHIKUN CHEN1Emergency, 2Infectious Diseases and 3General Practice, Jingmen No. 1 People's Hospital, Jingmen, Hubei 448000, P.R. ChinaDepartments of *Contributed equallyThe authors confirm that there are no further errors in the study, and all the authors agree to this correction. The authors regret their oversight, and apologize for any inconvenience caused."}
{"text": "In the current version of the Table S13, we have listed the correct values. The correction of this error does not affect any of the reported results or conclusions of the paper but nevertheless should be stated correctly. The authors sincerely apologize to the readers for this unintended lack of thoroughness and any confusion that may have resulted from that."}
{"text": "Retraction Note: Rice 14, 32 (2021)https://doi.org/10.1186/s12284-021-00474-zThe authors have retracted this article. Following publication, errors were discovered in Figure 1, Figure 5 and Table 1. The authors have stated that the phenotypic characterization of oslil3 mutant still needs further experiments to analyze the intermediate metabolites in carotene biosynthesis such as the contents of alfa-carotene and\u00a0beta-carotene, and that the analysis of oslil3 mutant is not precisely described. In addition, the authors have stated\u00a0that they need to further analyze the protein accumulation levels of OsPSYs in the mutant as compared with the WT via the PSYs specific antibodies to more accurately validate the interaction between LIL3 and PSYs. The authors intend to resubmit a revised manuscript. All authors agree with this retraction."}
{"text": "This abstract has been withdrawn."}
{"text": "Page 2: In the Fig. 1 legend, line 11, \u201creverse transcription [RT]\u201d should read \u201cretention time [RT].\u201dVolume 6, no. 5, e00585-21, 2021,"}
{"text": "The affiliation for the fourth author is incorrect. Nikita B. Gudimchuk is not affiliated with #3 but with #2. The full affiliation for Nikita B. Gudimchuk is as follows:1 Department of Physics, Lomonosov Moscow State University, Moscow, Russia, 2 Center for Theoretical Problems of Physicochemical Pharmacology, Moscow, Russia, 4 Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology, Moscow, Russia"}
{"text": "Rhizoctonia solani by Malik et al.(2019) should be Arshi Malik (2019)Bioinformation. 2019 15:227. PMID: 31285645The first author in \"Molecular docking and pharmacokinetic evaluation of natural compounds as targeted inhibitors against Crz1 protein in"}
{"text": "We are issuing this expression of concern in consultation with the publisher to fulfil their reporting obligation regarding the publication  mentioneOne of the authors has raised concerns regarding the methodology employed in the study, the conclusions drawn and the insufficient consideration of laboratory staff and resources. In order to keep the highest scientific standards, an in-depth investigation is initiated by the responsible editors together with the journal\u2019s editorial office in collaboration with the editorial board, and in accordance with the Committee on Publication Ethics (COPE) guidance. The article will be updated and any necessary corrections made at the conclusion of the investigation process."}
{"text": "The authors of  would liAudie L. Murphy Division, South Texas Veterans Health Care System, San Antonio, TX 78229, USA."}
{"text": "In Chenggui Wang,1"}
{"text": "When this paper first published, it was missing the below conflict of interest statements from the authors. These conflict of interest statements now appear in the paper online.Dr Patrick Blin wishes to record that he is an employee of the Bordeaux PharmacoEpi team in the University of Bordeaux, and the studies were performed by this team at the request of the French Health Technology Assessment agency, with a grant from Lundbeck and according to the European Network of Centres for Pharmacoepidemiology and Pharmacovigilance (ENCEEP) code of conduct and independence.Dr Fran\u00e7ois Paille wishes to record that he has received payments for consulting activity  and for invitations to speak at conferences connected with Lundbeck, Indivior and Pfizer."}
{"text": "There is an error in"}
{"text": "The authors declare that a patent application entitled \u201cCell-based vehicles for potentiation of viral therapy\u201d has been filed on August 8, 2019 by the inventors Dobrin Draganov and Aladar A. Szalay ["}
{"text": "The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates."}
{"text": "The authors wish to make the following changes to the published paper  as listecis-1,4-isoprene) were wrongly labelled and have been corrected as shown below.Chemical structures for poly(\u00df-oxidation should be replaced by oxiAB.oxiAB should be replaced by \u00df-oxidation.In the original manuscript,"}
{"text": "In"}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a satisfactory response. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, the authors contacted the office to inform us that they had made errors in the compilation of the tumour images shown in Fig. 4A. Further to the contact we received from these authors, an independent enquiry was conducted in the Editorial office, after which we were able to ascertain that the data in question had appeared in slightly modified form in another publication written by different authors 6 years previously. Owing to the fact that the contentious data in the above article had already been published elsewhere prior to its submission to"}
{"text": "HemaSphere. 2020;4:e356), the authors requested a change to their selected Creative Commons (CC) license. The license previously chosen was CC BY-NC-ND, but is now CC BY to comply with funding mandates. This adjustment has been made and does not affect the outcome of this publication.Since the publication of the article entitled \u201cRapid Emergence of Chronic Lymphocytic Leukemia During JAK2 Inhibitor Therapy in a Patient With Myelofibrosis\u201d (https://journals.lww.com/hemasphere/Fulltext/2020/06000/Rapid_Emergence_of_Chronic_Lymphocytic_Leukemia.9.aspxThe change has been made online:"}
{"text": "We welcome feedback from the authors Deng and Qin through their comment  on our pThank you for considering our response to the comment."}
{"text": "Under \u201cAssessment of Metals in Maternal Urine,\u201d the sentence on the limits of detection now reads as follows: \u201cThe limits of detection were 0.399 \u03bcg/L for arsenic, 0.066 \u03bcg/L for cadmium, 0.022 \u03bcg/L for lead, 0.016 \u03bcg/L for cobalt, 0.225 \u03bcg/L for copper, 0.090 \u03bcg/L for nickel, 0.008 \u03bcg/L for thallium, and 0.417 \u03bcg/L for zinc.\u201d This article has been corrected.1In the Original Investigation titled \u201cAssociation Between Prenatal Exposure to Metals and Atopic Dermatitis Among Children Aged 4 Years in Taiwan,\u201d"}
{"text": "The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates."}
{"text": "The final author in the author list, Professor Akio Matsubara , contacted the Editorial Office to say that he should not have been listed as an author in this published article. His inclusion as an author on the paper arose as a misunderstanding on the part of some of the other authors.The revised authorship on the paper is shown above, now excluding Akio Matsubara. All the remaining authors agree with the revision made to the authorship on this paper, and the authors remaining on the paper apologize for any inconvenience caused. Therefore, the revised authors\u2019 names and affiliations in this paper are as follows:1, Daiki Murata2, Shogo Inoue1, Tetsutaro Hayashi1, Koji Mita2, Yasuhisa Hasegawa3, Masao Kato4, Mitsuru Kajiwara5, Masanobu Shigeta6, Satoshi Maruyama7, Hiroyuki Moriyama8 and Seiji Fujiwara9Jun Teishima1Department of Urology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima 734-8551; 2Department of Urology, Hiroshima-City Asa Citizens Hospital, Hiroshima 731-0293; 3Department of Urology, Fukuyama Medical Center, Fukuyama, Hiroshima 720-8520; 4Department of Urology, Hiroshima General Hospital, Hatsukaichi, Hiroshima 738-8503; 5Department of Urology, Hiroshima Prefectural Hospital, Hiroshima 734-8530; 6Department of Urology, Kure Medical Center and Chugoku Cancer Center, Kure, Hiroshima 737-0023; 7Department of Urology, Miyoshi Central Hospital, Miyoshi, Tokushima 728-8502; 8Department of Urology, Onomichi General Hospital, Onomichi, Hiroshima 722-8508; 9Department of Urology, Higashi-Hiroshima Medical Center, Higashi-Hiroshima, Hiroshima 739-0041, Japan"}
{"text": "Correction to: Microbiome 10, 8 (2022)https://doi.org/10.1186/s40168-021-01202-xFollowing publication of the original article , the autFrom: \"JP, ML, and ZL designed the experiment; WX collected the samples, with the contribution of ZS and CD; JP and ZC performed the informatics work; JP, LL, and ML wrote the paper, with the contributions from all authors.\"To: \"JP, ML, and ZL designed the experiment; ZS and CD collected the samples; WX performed the laboratory works; JP and ZC performed the informatics works; JP, LL, and ML wrote the paper, with the contributions from all authors.\"The authors apologize for this error."}
{"text": "R. Soc. Open Sci.7, 192151 (Published 5 August 2020) (doi:10.1098/rsos.192151)This correction refers to an error in the numeric values reported in This error has no implications on the results and conclusions drawn in the publication. The paper has now been updated."}
{"text": "DOI: 10.1039/C9RA00302A.Correction for \u2018Investigation of plasma metabolomics and neurotransmitter dysfunction in the process of Alzheimer\u2019s disease rat induced by amyloid beta 25-35\u2019 by Mengying Wei  The authors regret that, due to personal negligence, The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "In the published version of this article, there was an error in the second sentence of the section \u2018Properties\u2019.The sentence \u2018It is a facultative aerobe that grows via aerobic respiration and anaerobic respiration with nitrate as the terminal electron acceptor.\u2019 should have read \u2018It is a facultative anaerobe that grows via aerobic respiration and anaerobic respiration with nitrate as the terminal electron acceptor\u2019.The authors apologise for any inconvenience caused."}
{"text": "There is an error in affiliation 2 for authors Zawiyah Mohammad Yusof and Hazura Mohamed. The correct affiliation 2 is: Faculty of Information Science and Technology, Universiti Kebangsaan Malaysia, Selangor, Malaysia."}
{"text": "Alam  The authors regret that in the published version of the above article the position of the footnote symbol (\u2020) indicating three authors who contributed equally to the paper was incorrect. The footnote symbol should be positioned after the first three authors Israt S. Alam,\u2020 Rory L. Arrowsmith,\u2020 and Fernando Cortezon-Tamarit\u2020 as shown above.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Erratum zu:Pathologe 202110.1007/s00292-021-00986-xIn Abb."}
{"text": "Correction to: Environ Sci Pollut Res (2020) 27:26103\u20132611410.1007/s11356-020-08881-3The correct Supplementary Material is presented in this paper.ESM 1(PDF 458 kb)"}
{"text": "In the \u201cExperimental Procedures\u201d section, in the subsection \u201cDifferentiation of iPSCs to HSs,\u201d the text \u201cTo promote hippocampal differentiation, NDM was supplemented with CHIR-99021 \u2026\u201d now reads, \u201cTo promote hippocampal differentiation, NDM was supplemented with CHIR-99021 \u2026\u201d(2)Page 4 of the supplemental information. In the section \u201cSUPPLEMENTAL EXPERIMENTAL PROCEDURES,\u201d in the subsection \u201cDifferentiation of iPSCs to hippocampal spheroids,\u201d the text \u201cTo promote hippocampal differentiation, NDM was supplemented with CHIR-99021 \u2026\u201d now reads, \u201cTo promote hippocampal differentiation, NDM was supplemented with CHIR-99021 \u2026\u201d(3)Page 4 of the supplemental information. In the section \u201cSUPPLEMENTAL EXPERIMENTAL PROCEDURES,\u201d in the subsection \u201cDifferentiation of iPSCs to hippocampal spheroids,\u201d the text \u201cAdherent cells were grown for 6\u00a0days in NDM supplemented with CHIR-99021 (0.5\u00a0mM)\u2026\u201d now reads, \u201cAdherent cells were grown for 6\u00a0days in NDM supplemented with CHIR-99021 (0.5\u00a0\u03bcM)\u2026\u201dThe authors would like to thank their colleagues for identifying this error and apologize for any inconvenience caused. These instances in the manuscript online and in the supplemental information have now been corrected. The text that reads differently is provided below."}
{"text": "Injection targets including fat compartments and potential spaces will be outlined in key facial aesthetic subunits, including temple, cheek, lip, and jawline.This video will discuss high yield 3-dimensional surface topography landmarks for facial filler injections."}
{"text": "The authors would like to update the supplementary information in the published original version. The updated supplementary material is provided in this correction.Supplementary file1 (PDF 1110 kb)Below is the link to the electronic supplementary material."}
{"text": "Subsequently to the publication of the above paper, the authors realized that the layouts of Consequently, the correctly organized versions of"}
{"text": "The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates."}
{"text": "RETRACTED  RETRACTED RETRACTED RETRACTED RETRACTED"}
{"text": "The Introduction to Part I contains an overview of both issues [This issue is the second part of a two-part issue on \u2018Voice modulation: from origin and mechanism to social impact\u2019. Part I can be found at"}
{"text": "For the authors Ladan Khodaparast, Laleh Khodaparast, Bert Houben, Frederic Rousseau, and Joost Schymkowitz, the affiliation \u201cVIB, Center for Brain & Disease Research, Leuven, Belgium\u201d should be included as shown above.Volume 12, no. 4, e01129-21, 2021,"}
{"text": "After publication of the original article , the autThese errors have been corrected in the original article. Please find below a summary of the errors that have been corrected:\u201c6.7 million\u201d had been written instead of \u201c8.8 million\u201d\u201c90.5%\u201d had been written instead of \u201c61%\u201dIn the Results of the Abstract:\u201c50.92%\u201d had been written instead of \u201c38.82%\u201dIn Table 2, in the row \u2018AOM Myringotomy\u2019:\u201823.8%\u201d had been given for the effectiveness estimate of PCV13 against all-cause pneumonia\u2019, while the value should read \u201823.7%\u2019.In the subsection \u2018All-cause pneumonia effectiveness\u2019:\u201c17\u201d and \u201c17\u201d, respectively, had been detailed instead of \u201c19\u201d and \u201c19\u201d, respectivelyIn Table 6, in the row \u2018Death due to IPD/pneumonia\u2019, under columns \u2018PCV13 (A)\u2019 and \u2018PHiD-CV (B)\u2019, respectively:\u201cNTD 557 957\u201d had been written instead of \u201cNTD 557 887\u201dIn Table 6, in the row \u2018All-cause pneumonia\u2019, under the column \u2018Difference (B\u2013A)\u2019:\u2212\u20090.6 had been written instead of \u2212\u00a05.9\u2212\u20096.6 had been written instead of \u2212\u20098.8\u2212\u20093.9 had been written instead of \u2212\u20094.8\u2212\u20090.8 had been written instead of \u2212\u20091.2\u2212\u20097.1 had been written instead of \u2212\u20099.3\u2212\u200914.4 had been written instead of \u2212\u200919.60.15 had been written instead of 5.5\u2212\u20096.7 had been written instead of \u2212\u20098.8\u2212\u200988.2 had been written instead of \u2212\u00a090.4In Table 8, column \u2018Cost (millions)\u2019 (in descending order):8 had been written instead of 146 had been written instead of 521 had been written instead of 2238 had been written instead of 3938 had been written instead of \u2212\u200912In Table 8, column \u2018QALY\u2019 (in descending order):\u201c\u2212\u00a06.7 million\u201d had been written instead of \u201c\u2212\u00a08.8 million\u2019In the Footnote of Table 8:\u201cThe supplementary Fig. 2 stresses the general context and observations that were made in the present study.\u201dAt the end of the \u2018Conclusion\u2019, the following sentence was missing:The authors apologize for any inconvenience caused."}
{"text": "BMJ Open Resp Res 2021;8:e000857.Wilcox CR, Islam N, Dambha-Miller H. Association between influenza vaccination and hospitalisation or all-cause mortality in people with COVID-19: a retrospective cohort study. The authors want to alert readers to the following correction made to the published version.Christopher Wilcox and Nazrul Islam are the joint first authors."}
{"text": "In \u201cToward Designs of Workplace Stress Management Mobile Apps for Frontline Health Workers During the COVID-19 Pandemic and Beyond: Mixed Methods Qualitative Study\u201d :e30640) the authors noted one error.In the originally published manuscript, the title was incorrectly set as:Toward Designs of Workplace Stress Management Mobile Apps for Frontline Health Workers During the COVID-19 Pandemic and Beyond: Design Implications for a Mixed Methods Qualitative StudyThe title has been corrected to:Toward Designs of Workplace Stress Management Mobile Apps for Frontline Health Workers During the COVID-19 Pandemic and Beyond: Mixed Methods Qualitative StudyThe correction will appear in the online version of the paper on the JMIR Publications website on January 25, 2022, together with the publication of this correction notice. Because this was made after submission to PubMed, PubMed Central, and other full-text repositories, the corrected article has also been resubmitted to those repositories."}
{"text": "The axis labels for"}
{"text": "The authors wish to make the following corrections to this paper :The affiliation of Tom\u00e1\u0161 Tak\u00e1\u010d should have been:Centre of the Region Han\u00e1 for Biotechnological and Agricultural Research, Department of Cell Biology, Faculty of Science, Palack\u00fd University Olomouc, 783 75 Olomouc, Czech Republic; tomas.takac@upol.czThe authors apologize for any inconvenience that may have been caused."}
{"text": "Figs"}
{"text": "The captions for Figs"}
{"text": "There is hope that the Russian war on Ukraine could expedite the energy transition in Europe leading to a new and more environmentally sustainable steady state."}
{"text": "CD137 and PD-L1 targeting with immunovirotherapy induces a potent and durable antitumor immune response in glioblastoma models. Journal for ImmunoTherapy of Cancer 2021;9:e002644. doi: 10.1136/jitc-2021-002644Puigdelloses M, Garcia-Moure M, Labiano S, This paper has been updated since first published to amend author name 'Jaime G\u00e1llego P\u00e9rez-Larraya'."}
{"text": "In"}
{"text": "In the right notes of Fig.\u00a0There add efferent nerve fibers at the bottom of hair cells in both Figs. The authors found mistakes in 2 figures of their publication \"Progress in protecting vestibular hair cells \", published online 13 May 2021. They have redrawn Fig."}
{"text": "The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates."}
{"text": "Please find the retraction statement below:Following publication, concerns were raised regarding image manipulation and duplication. The authors failed to provide a satisfactory explanation during the investigation, which was conducted in accordance with Frontiers\u2019 policies.This retraction was approved by the Chief Editors of Frontiers in Oncology and Chief Executive Editor. The authors agreed to this retraction."}
{"text": "The online version has been amended.In this paper by Jasper Tromp and colleagues (BMJ 2021;372:n461, doi:"}
{"text": "Following publication of the original article , the aut1Biomechanics Labs of Orthopaedics Institute, Tianjin Hospital, Tianjin, 300050 People\u2019s Republic of China\u201d to \u201c1Biomechanics Labs of Orthopaedics Institute, Clinical College of Orthopedics, Tianjin Medical University, Tianjin, 300050 People\u2019s Republic of China\u201d.The correct affiliation should be changed from \u201c"}
{"text": "In the originally published version of this manuscript, Figure S5E included duplicated fluorescent images. The incorrect version was included due to a technical oversight from the production team.The production team regrets this error.1"}
{"text": "This issue focuses on how nutrition and environment interacts with the epigenome and may influence phenotypic expression. The ultimate consequences on animal production and animal health are examined for their potential application to animal agriculture ."}
{"text": "Therefore, the revised version of the Funding section paragraph should read as follows:"}
{"text": "The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates."}
{"text": "In our paper"}
{"text": "The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates."}
{"text": "Here is the updated graphic for"}
{"text": "The corrected version of the figure with the R group as (CH2)4Ph is shown below.The authors regret that an incorrect version of The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "In"}
{"text": "In the abstract \u201cPublic health guidance for the COVID\u201019 pandemic: A preliminary qualitative analysis,\u201dAdria Lam, Peter Taber, Elisa Rocha, Saifon Phengphoo, Guilherme Del Fiol, Catherine J. Staes, Saverio M. Maviglia, Roberto A. Rocha.We apologize for this error."}
{"text": "In the original publication the labelling in middle and bottom panels of Fig."}
{"text": "Sci., 2018, 9, 6325\u20136339, DOI: 10.1039/C8SC01043A.Correction for \u2018Polariton chemistry: controlling molecular dynamics with optical cavities\u2019 by Raphael F. Ribeiro  The authors regret that incorrect values are reported in The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "The authors regret that the affiliations were incorrectly shown in the original manuscript. The corrected list of affiliations is as shown above.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "We appreciate the commentary by Mrakic-Sposta et al. on our published article . We apol2\u2212 and \u00b7OH [We are also glad about the further input regarding the capability of the technique to be applied to frozen/stored samples, including frozen saliva . Indeed, and \u00b7OH  and anti and \u00b7OH ), and th and \u00b7OH , or ROS, and \u00b7OH . Thus, w"}
{"text": "Because they exert cross-border spillover effects, fiscal policies of individual EU member states are a common concern for the entire EU."}
{"text": "Image-guidance for frame-based stereotaxis is facilitated by incorporating three to four N-localizers\u00a0or Sturm-Pastyr localizers\u00a0into a stereotactic frame. An extant frame that incorporates only two N-localizers violates the fundamental principle of the N-localizer, which requires three non-colinear points to define a plane in three-dimensional space. Hence, this two N-localizer configuration is susceptible to error. The present article proposes the V-localizer that comprises multiple diagonal bars to provide four or more non-colinear points to minimize\u00a0error. Image-guidance for frame-based stereotaxis is facilitated by incorporating three to four N-localizers or Sturm-Pastyr localizers into a stereotactic frame ,2. Montege plane .Overview of the V-localizerTo enable the incorporation of only two localizers, wherein one localizer is attached to each lateral face of a rectangular stereotactic frame, several localizers that comprise\u00a0two or more diagonal bars  have been proposed recently . The mosFigure Figure Monte Carlo simulationThis article reports root mean square errors (RMSe) calculated via MC\u00a0simulation for the two and four V-localizer configurations. These RMSe are compared\u00a0to the RMSe for the M-localizer, the Z-localizer, a four N-localizer configuration, and the\u00a0Brown-Roberts-Wells (BRW) localizer that embodies a\u00a0three N-localizer configuration\u00a0,4,7. MC The transformation of a target point from 2D to 3D is facilitated by fiducials; for example, the fiducials depicted in Figure nal bars . This apnal bars . The oveMC simulation randomly perturbs the For each type of localizer, MC simulation performs Figure nal bars . Fourth,nal bars ,9,10.The low-slope diagonal bars of the V-localizer abut against vertical bars, as shown in Figure\u00a0Figure The four V-localizer configuration creates two colinear sets of fiducials that lie in close proximity to one another near each of the left and right edges of the CT image, as shown in Figure\u00a0Figure Figure The BRW localizer and the four N-localizer configuration have two advantages relative to the M-localizer, Z-localizer, and V-localizer. First, because the three N-localizers of the BRW localizer are positioned at In contrast to the four N-localizer configuration, the BRW localizer shares an important feature with the M-localizer, Z-localizer, and V-localizer. None of its three N-localizers obscure\u00a0the patient's face; hence, claustrophobia is eliminated and patient comfort is maintained.\u00a0In contrast to the BRW localizer and the four N-localizer configuration, none of the M-localizer, Z-localizer, or V-localizer surround the patient's cranium; hence, all of them are more susceptible to error anteriorly and posteriorly than laterally. Moreover, with the possible exception of the M-localizer, they lack the simplicity of the N-localizer.The M-localizer, Z-localizer, and V-localizer are all designed for attachment to the two lateral faces of a rectangular stereotactic frame. These localizers all create sufficient fiducials in a CT image to determine the three-dimensional spatial orientation of the CT image plane relative to the stereotactic frame. With the possible exception of the M-localizer, they create more complex fiducial patterns than do\u00a0the four N-localizer configuration and the BRW localizer.Monte Carlo simulations have calculated the RMSe for the M-localizer, Z-localizer, BRW localizer,\u00a0two and four V-localizer configurations, and\u00a0four N-localizer configuration. The simulations predict the following comparative accuracies for these localizers. The M-localizer, Z-localizer, and V-localizer are less accurate anteriorly and posteriorly\u00a0than laterally. The accuracies of the Z-localizer, BRW localizer, four N-localizer configuration, and four V-localizer configuration\u00a0are symmetric side-to-side but the accuracies of the two V-localizer configuration and the M-localizer are asymmetric side-to-side. The\u00a0two V-localizer configuration and the BRW localizer are more accurate than the M-localizer. The Z-localizer and both V-localizer configurations are more accurate than the BRW localizer. The four V-localizer configuration is more accurate than the four N-localizer configuration and hence is the most accurate of all localizers."}
{"text": "In this paper, the phrases should be corrected as follows:1C2C5 \u2245 0.65.\u201dFor \u201ccoefficients jointly takes a value of C1C2C5 \u2245 1.0.\u201dRead \u201ccoefficients jointly takes a value of C1\u00b7C2\u00b7C5 = 0.65.\u201dFor \u201cjointly as C1\u00b7C2\u00b7C5 = 1.0.\u201dRead \u201cjointly as C"}
{"text": "The authors wish to make the following erratum to this paper :youribroekhuizen@me.com (Y.C.B.B.); m.w.jaspers@amc.uva.nl (M.W.M.J.); their contributions: writing\u2014original draft: Y.C.B.B.; conceptualization, writing\u2014review and editing: M.W.M.J.The addition of authors Youri C. B. Broekhuizen and Monique W. M. Jaspers due to an omission. Additionally, their affiliation and emails: Center of Human Factors Engineering of Health Information Technology (HIT-Lab), Institute of Biomedical Informatics, Amsterdam Public Health Research Institute\u2014Location Academic Medical Center (AMC), University of Amsterdam (UvA), 1012 WX Amsterdam, The Netherlands; The authors would like to apologize for any inconvenience caused to the readers by these changes."}
{"text": "Retracted RetractedRetractedRetractedRetractedRetracted"}
{"text": "Text TK."}
{"text": "Page 4: This erratum corrects Volume 12, no. 4, e01548-21, 2021,"}
{"text": "Lanosterol in the ligand-binding pocket (LBP) of CYP51 that was published [In the original publication, there was a mistake in"}
{"text": "Molecular Medicine Reports for allowing them the opportunity to publish this corrigendum, and apologize to the readership of the Journal and to the funding body in question for any inconvenience caused.The authors regret their oversight in providing this incorrect information in the Funding section of their paper. They thank the Editor of"}
{"text": "The authors regret that the image of BCP group without Cal in 12 W in the Fig."}
{"text": "More than other EU \u2018Unions\u2019, the proposed Health Union requires proper definition because the EU\u2019s competences are limited in this domain."}
{"text": "Figure\u00a01 has now been corrected online and appears below. This change does not affect the conclusions of the paper. The authors sincerely apologize to the readers for any confusion that may have resulted from this error."}
{"text": "The authors used only 60 fmol of DNA template per 10 \u03bcl PURE reaction.In Materials and Methods, under the section \u2018Expressing protein and measuring fluorescence The authors apologise for this error."}
{"text": "Furthermore, Fig. 3 contained data that bore striking similarities to data published in Fig. 6 in another paper published in Molecular Medicine Reports has determined that the above paper should be retracted from the Journal on account of a lack of confidence concerning the originality and the authenticity of the data. The authors were asked for an explanation to account for these concerns, but the Editorial Office never received any reply. The Editor regrets any inconvenience that has been caused to the readership of the Journal.After having conducted an independent investigation in the Editorial Office, the Editor of"}
{"text": "Page 1: The affiliations should appear as given in this Erratum.Volume 9, no. 1, e00022-21, 2021,"}
{"text": "The authors would like to correct an error in the name of the condition in the recently published paper . The ter"}
{"text": "P\u00a0=\u00a00.30) nor reduced non-fatal cardiovascular outcomes  and docosahexaenoic acid (DHA) with suboptimal statin therapy can bias results in favor of EPA+DHA. The authors correctly pointed out that GISSI-P outcomes .FigureMeOur meta-analysis Safi U. Khan: data abstraction, analysis, and manuscript drafting.Deepak L. Bhatt: supervision and critical revision.Dr. Safi Khan has nothing to disclose.Dr. Bhatt reports grants from Amarin, grants from AstraZeneca, grants from Bristol-Myers Squibb, grants from Eisai, grants from Ethicon, grants from Medtronic, grants from sanofi aventis, grants from The Medicines Company, other from FlowCo, grants and other from PLx Pharma, other from Takeda, personal fees from Duke Clinical Research Institute, personal fees from Mayo Clinic, personal fees from Population Health Research Institute, personal fees, non-financial support and other from American College of Cardiology, personal fees from Belvoir Publications, personal fees from Slack Publications, personal fees from WebMD, personal fees from Elsevier, other from Medscape Cardiology, other from Regado Biosciences, other from Boston VA Research Institute, personal fees and non-financial support from Society of Cardiovascular Patient Care, non-financial support from American Heart Association, personal fees from HMP Global, grants from Roche, personal fees from Harvard Clinical Research Institute , other from Clinical Cardiology, personal fees from Journal of the American College of Cardiology, other from VA, grants from Pfizer, grants from Forest Laboratories/AstraZeneca, grants from Ischemix, other from St. Jude Medical (now Abbott), other from Biotronik, grants and other from Cardax, other from Boston Scientific, grants from Amgen, grants from Lilly, grants from Chiesi, grants from Ironwood, personal fees from Cleveland Clinic, personal fees from Mount Sinai School of Medicine, other from Merck, grants from Abbott, grants from Regeneron, other from Svelte, grants and other from PhaseBio, grants from Idorsia, grants from Synaptic, personal fees from TobeSoft, grants, personal fees and other from Boehringer Ingelheim, personal fees from Bayer, grants and other from Novo Nordisk, grants from Fractyl, personal fees from Medtelligence/ReachMD, personal fees from CSL Behring, grants and other from Cereno Scientific, grants from Afimmune, grants from Ferring Pharmaceuticals, other from CSI, grants from Lexicon, personal fees from MJH Life Sciences, personal fees from Level Ex, grants from Contego Medical, grants and other from CellProthera, personal fees from K2P, personal fees from Canadian Medical and Surgical Knowledge Translation Research Group, grants and other from MyoKardia/BMS, grants from Owkin, grants from HLS Therapeutics, grants and other from Janssen, grants from 89Bio, grants and other from Novo Nordisk, grants from Garmin, grants and other from Novartis, grants and other from NirvaMed, other from Philips, outside the submitted work."}
{"text": "Sci., 2022, DOI: 10.1039/d1sc06035j.Correction for \u2018Catalytic asymmetric hydrometallation of cyclobutenes with salicylaldehydes\u2019 by F. Wieland Goetzke  The authors regret that the absolute stereochemistry in The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "The authors regret that an incorrect version of The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "The authors regret that some incorrect representative images were accidentally used in our previously published paper"}
{"text": "Furthermore, Fig. 6 contained data that bore striking similarities to data published in Fig. 8 in another paper published in Molecular Medicine Reports has determined that the above paper should be retracted from the Journal on account of a lack of confidence concerning the originality and the authenticity of the data. The authors were asked for an explanation to account for these concerns, but the Editorial Office never received any reply. The Editor regrets any inconvenience that has been caused to the readership of the Journal.After having conducted an independent investigation in the Editorial Office, the Editor of"}
{"text": "There is an error in the caption for"}
{"text": "The lecture will be given by the 2020 Baltes Award recipient, William Chopik, PhD, of Michigan State University. The recipient of the 2021 Baltes Award is Laura B. Zahodne, PhD, of the University of Michigan. The Margret M. and Paul B. Baltes Foundation Award in Behavioral and Social Gerontology recognizes outstanding early-career contributions in behavioral and social gerontology. The award is generously funded by the Margret M. and Paul B. Baltes Foundation."}
{"text": "An incorrect version of"}
{"text": "In"}
{"text": "The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates."}
{"text": "Nature Genetics 10.1038/s41588-021-00790-6, published nline 25 February 2021.Correction to: This paper was originally published without open access. As of the date of this correction, the paper is available online as an open-access paper under a Creative Commons Attribution 4.0 International License. The Acknowledgements have additionally been updated to specify the funding agency for NCI Cancer Moonshot grant U2CCA233311."}
{"text": "The following scientists assisted the journal by reviewing manuscripts during the period November 1, 2020 to October 31, 2021.We gratefully acknowledge their critical evaluation and assistance in selecting articles for publication."}
{"text": "Sci., 2021, DOI: 10.1039/D1SC01748A.Correction for \u2018Development of a structure-based computational simulation to optimize the blocking efficacy of pro-antibodies\u2019 by Bo-Cheng Huang  The authors regret that a funding source was omitted from the original article. The following funding information should have been acknowledged: Ministry of Science and Technology, Taiwan (MOST 109-2627-M-037-001) and Kaohsiung Medical University, Taiwan (KMU-DK(B)11000-4).The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "African Health Sciences. The supplement epitomizes successful completion of training of African fellows in Global leadership. The fellows have authored diverse manuscripts in three themes: HIV, reproductive and child health.Welcome to this Afya Bora supplement of This is a welcome break from the COVID-19 pandemic. The HIV papers are basically on antiretroviral therapy (ART), with special emphasis on outcome"}
{"text": "Chem., 2021, 12, 1765\u20131770, DOI: 10.1039/D1MD00215E.Correction for \u2018Estimating the cooperativity of PROTAC-induced ternary complexes using  The sentence \u201cCMP98 (The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Correction to: Oncogene;10.1038/onc.2015.355; Published online 21 Sept 2015In Fig."}
{"text": "The original publication of this article  containeIncorrectPXD00008293.The mass spectrometry proteomics data have been deposited to the ProteomeXchange Consortium [16] via the PRIDE partner repository with the dataset identifier CorrectPXD008293.The mass spectrometry proteomics data have been deposited to the ProteomeXchange Consortium [16] via the PRIDE partner repository with the dataset identifier IncorrectPXD00008293.The SILAC mass spectrometry proteomics data have been deposited to the ProteomeXchange Consortium (16) via the PRIDE partner repository with the dataset identifier CorrectPXD008293.The SILAC mass spectrometry proteomics data have been deposited to the ProteomeXchange Consortium (16) via the PRIDE partner repository with the dataset identifier"}
{"text": "Sustainability in livestock production systems will play a critical role in reaching the Sustainable Development Goals developed by the United Nations . Globall"}
{"text": "There is an error in Figs"}
{"text": "Correction to: Diabetologia10.1007/s00125-021-05391-wThis paper was published with Open Access. The copyright line has been updated to indicate that the authors retain copyright."}
{"text": "The captions for Figs"}
{"text": "Nature Genetics 10.1038/s41588-020-00750-6, published online 7 January 2021.Correction to: This paper was originally published without open access. As of the date of this correction, the paper is available online as an open-access paper under a Creative Commons Attribution 4.0 International License."}
{"text": "We regret the unprofessional behavior of the authors involved.hongruiyan001@163.com> (new email)Correspondence: Ruihong Yan: <"}
{"text": "In"}
{"text": "Furthermore, Figs. 5 and 6 in the above paper appeared to share data with Figs. 7 and 11, respectively, in a paper published in Phytomedicine .Following the publication of the above paper, a concerned reader drew to the Editor's attention that several figures bore striking similarities to other papers that were published at around the same time written by different authors based in different research institutions. Fig. 3 (in colour) was essentially the same as a greyscale figure  in a paper published in Molecular Medicine Reports has determined that the above paper should be retracted from the Journal on account of a lack of confidence concerning the originality and the authenticity of the data. The authors were asked for an explanation to account for these concerns, but the Editorial Office never received any reply. The Editor regrets any inconvenience that has been caused to the readership of the Journal.After having conducted an independent investigation in the Editorial Office, the Editor of"}
{"text": "After this article  was publSpecifically:In Figure 1A in this article, the 0 RBV (\u03bcg/ml), 100 IFN-\u03b1 (IU/ml) panel appears similar to the 40 RBV (\u03bcg/ml), 10 IFN-\u03b1 (IU/ml) panel; the 10 RBV (\u03bcg/ml), 0 IFN-\u03b1 (IU/ml) panel appears similar to the 20 RBV (\u03bcg/ml), 10 IFN-\u03b1 (IU/ml) panel; and the 20 RBV (\u03bcg/ml), 0 IFN-\u03b1 (IU/ml) panel appears similar to the 20 RBV (\u03bcg/ml), 1000 IFN-\u03b1 (IU/ml) panel.In Figure 1D in this article, the 0 RBV (\u03bcg/ml), 100 IFN-\u03b1 (IU/ml) panel appears similar to the 10 RBV (\u03bcg/ml), 10 IFN-\u03b1 (IU/ml) panel; and the 0 RBV (\u03bcg/ml), 250 IFN-\u03b1 (IU/ml) appears similar to the 20 RBV (\u03bcg/ml), 250 IFN-\u03b1 (IU/ml) panel.PLOS ONE Editors issue this Expression of Concern.Follow-up on these issues is ongoing; in the meantime, the In addition, please note that reference 16 in this article ."}
{"text": "CLL-IPI\u4e0eCSI\u7ec4\u5408\u6784\u5efa\u65b0\u578b\u9884\u540e\u8bc4\u5206\u4f53\u7cfb\uff1a\u6211\u4eec\u5c06CLL-IPI\u4e0eCSI\u7ec4\u5408\u6784\u5efa\u65b0\u7684\u9884\u540e\u8bc4\u5206\u6a21\u578b\u5e76\u901a\u8fc7ROC\u66f2\u7ebf\u548cAUC\u8bc4\u4f30\u9884\u6d4b\u7cbe\u5ea6\u3002\u7ed3\u679c\u663e\u793a\uff0c\u5bf9\u4e8eOS\uff0cCSI\u8054\u5408CLL-IPI\u8f83\u5355\u7eafCLL-IPI\u7684AUC\u503c\u66f4\u9ad8\u4e14\u5dee\u5f02\u5177\u6709\u7edf\u8ba1\u5b66\u610f\u4e49\uff080.783\u5bf90.761\uff0cCLL\u60a3\u8005\u7684\u4e34\u5e8a\u8fc7\u7a0b\u5448\u9ad8\u5ea6\u5f02\u8d28\u6027\uff0c\u65b0\u836f\u6216\u65b0\u7684\u6cbb\u7597\u7b56\u7565\u5df2\u7ecf\u53ef\u4ee5\u514b\u670d\u6216\u90e8\u5206\u514b\u670d\u4e00\u4e9b\u65e2\u5f80\u4e0d\u826f\u9884\u540e\u56e0\u7d20\uff0c\u4f46\u7531\u4e8e\u7ecf\u6d4e\u548c\u6280\u672f\u4e0a\u7684\u9650\u5236\uff0c\u4ecd\u7136\u6709\u5fc5\u8981\u8fdb\u4e00\u6b65\u63a2\u7d22\u65b0\u7684\u9884\u540e\u56e0\u7d20\u3002\u8840\u6813\u6813\u585e\u662f\u764c\u75c7\u6b7b\u4ea1\u7684\u7b2c\u4e8c\u5927\u539f\u56e0DD\u662f\u7ea4\u7ef4\u86cb\u767d\u964d\u89e3\u7684\u6700\u7ec8\u4ea7\u7269\uff0c\u6709\u7814\u7a76\u663e\u793a\u5176\u4e3a\u8bb8\u591a\u5b9e\u4f53\u7624\u7684\u9884\u540e\u6807\u5fd7\u7269Mohren\u7b49\u672c\u7814\u7a76\u56de\u987e\u6027\u5206\u6790\u4e86329\u4f8b\u521d\u8bcaCLL\u60a3\u8005\uff0c\u7ed3\u679c\u8868\u660e\u9ad8\u6c34\u5e73APTT\u548cDD\u4e0e\u60a3\u8005TTFT\u548cOS\u65f6\u95f4\u7f29\u77ed\u76f8\u5173\u3002\u5728\u6b64\u57fa\u7840\u4e0a\uff0c\u6211\u4eec\u63d0\u51fa\u4e86\u4e00\u79cd\u65b0\u7684\u9884\u540e\u6a21\u578b\u2014\u2014CSI\uff0cCSI\u8f83\u9ad8\u7684\u60a3\u8005\u5177\u6709\u8f83\u5dee\u7684TTFT\u548cOS\u3002\u800cCSI\u8054\u5408CLL-IPI\u80fd\u66f4\u597d\u5730\u9884\u6d4bCLL\u60a3\u8005\u7684OS\u3002\u603b\u4e4b\uff0cAPTT\u548cDD\u6c34\u5e73\u9ad8\u7684CLL\u60a3\u8005TTFT\u3001OS\u5dee\u3002\u800c\u7531\u8fd9\u4e24\u9879\u6307\u6807\u7ec4\u6210\u7684CSI\u8054\u5408CLL-IPI\u53ef\u4ee5\u63d0\u9ad8\u540e\u8005\u5bf9OS\u7684\u9884\u6d4b\u80fd\u529b\u3002\u4f46\u7531\u4e8e\u672c\u9879\u7814\u7a76\u4e3a\u56de\u987e\u6027\u7814\u7a76\u4e14\u7eb3\u5165\u75c5\u4f8b\u4ec5\u6765\u6e90\u4e8e\u5355\u4e2d\u5fc3\uff0c\u53ef\u80fd\u5b58\u5728\u504f\u501a\uff0c\u672a\u6765\u4ecd\u9700\u591a\u4e2d\u5fc3\u548c\u524d\u77bb\u6027\u7814\u7a76\u9a8c\u8bc1\u76f8\u5173\u7ed3\u8bba\u3002"}
{"text": "Dr. Hodes will provide an overview of NIA's structure and mission, in addition to discussing research foci from across the Institute's scientific divisions."}
{"text": "Commun., 2018, 54, 12234\u201312237.Correction for 'CuAAC click chemistry for the enhanced detection of novel alkyne-based natural product toxins' by Edward S. Hems  The authors regret that The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "The original Competing Interests statement is incomplete. An updated Competing Interests statement is as follows: SMT is a former employee of Senseye, Inc. (2015\u20132016) and is named as a co-inventor on a patent/patent application(s) related to eye movement and mental state . SMT does not consider this a potential competing interest. The other authors have declared that no competing interests exist."}
{"text": "The authors independently contacted the Editorial Office requesting that the paper be retracted.Following the publication of this paper, an interested reader drew to the attention of the Office that the GAPDH control bands shown in Fig. 5 were strikingly similar to data appearing in different form in other articles by different authors. Owing to the fact that the contentious data in the above article had already been published elsewhere, or were already under consideration for publication, prior to its submission to The Editor apologizes to the readership for any inconvenience caused."}
{"text": "In"}
{"text": "Pharmaceutical Biotechnology with the companion article, \u201cMechanism of Thimerosal-Induced Structural Destabilization of a Recombinant Rotavirus P[4] Protein Antigen Formulated as a Multi-Dose Vaccine\u201d [J Pharm Sci 110 (2021) 1054\u20131066].This paper was miscategorized in the March 2021 issue and should have been included under the subject category of"}
{"text": "The accession code will be added in Section 2.8. Structural Features of Iripin-8: The coordinates and structure factors of Iripin-8 are deposited in the Protein Data Bank under accession code 7PMU.This addendum does not cause any changes to the results or conclusions in the original published paper ."}
{"text": "The Funding statement is incorrect. The correct statement is: Funding to support open access publication of this manuscript was provided by The Society for Companion Animal Studies (SCAS)."}
{"text": "There is an error in affiliation designation for authors Caroline Goujon and Olivier Moncorg\u00e9. The correct affiliation is affiliation 3: Institut de Recherche en Infectiologie de Montpellier (IRIM), UMR 9004\u2014CNRS, Universit\u00e9 de Montpellier, Montpellier, France."}
{"text": "In our paper"}
{"text": "British Journal of Cancer (2020); 10.1038/s41416-020-01145-4, published online 5 November 2020Correction to: Since the publication of this paper the authors have noticed an error in the name of Wouter Hendrickx, where Dr. Hendrickx\u2019s name was incorrectly listed as Wouter Hendricks. This has been corrected above."}
{"text": "They alerted the Editorial Office to the fact that the same data, albeit with a different view, had been selected to show the \u2018CON\u2019 and \u2018NC\u2019 experiments for the colony-formation assays featured in Fig. 6. The Editor has agreed to the authors\u2019 request that the paper be retracted. All the authors agree to this retraction, and apologize for any inconvenience caused."}
{"text": "The authors regret that the original version of this paper"}
{"text": "The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates."}
{"text": "Due to the sensitive nature of this topic and the associated health and safety risks,this case report is being retracted and the content has been removed, both at therequest of the authors and with the agreement of the editors"}
{"text": "Due to a misunderstanding between authors, two of the original authors were not listed on this article at the time of submission and publication. All three authors have discussed this and determined that adding the two missing authors is the best solution. The two new authors are:Neha ShahDepartment of Physical Medicine and Rehabilitation, Northwestern Medicine at Marianjoy Rehabilitation Hospital, Wheaton, USAPrempreet BajajDepartment of Orthopedic Surgery and Rehabilitation, Loyola University Medical Center, Maywood, USA"}
{"text": "Dear Editor,The diverse microbial community present in the human intestine plays a vital role in translating the food to nutrients and metabolites essential for maintaining host physiology, including digestion, lipid and glucose metabolism, immune homeostasis, and proper development of the brain and cognitive functions . Consumal., 2018). Modulaal., 2018). The poal., 2018; \u00c1ngel Gal., 2018). A deepal., 2018; Conternal., 2018; de Olival., 2018; Guevaraal., 2018; Istas eal., 2018; Lima etal., 2018; Medina-al., 2018; Ntemirial., 2018; Park etal., 2018; Vilela al., 2018) summariThe authors thank the American University of Ras Al Khaimah for the support and facilities provided.The authors declare no conflict of interest."}
{"text": "The captions for Figs"}
{"text": "The captions for Figs"}
{"text": "After having been in contact with the authors, they agreed with the decision to retract the paper. The Editor apologizes to the readership for any inconvenience caused.Owing to the fact that the contentious data in the above article had already appeared in different form in other articles prior to its submission to"}
{"text": "In"}
{"text": "The authors wish to make the following corrections to this paper : in the In Abstract: Every year, the world is producing around 100 million tons of waste glass (WG), the majority of them are going to landfills that create massive environmental problems.In Introduction: (first sentence of second paragraph)Globally, around 130 million tons of glass are being produced each year among which approximately 100 million tons are being discarded as waste. The authors apologize for this error and state that the scientific conclusions are unaffected. The original article has been updated."}
{"text": "Lycopene is a C40 tetraterpene that is composed of eight isoprene units joined by regular head to tail bindings, except in the middle of the molecule, where tail to tail binding forms an asymmetric structure  . Its abThis work was supported by the Incheon National University Research Concentration Professors Grant in 2021.The authors declare no conflict of interest."}
{"text": "This article has been corrected: In Figure 6D authors mistakenly used the same picture for si-LRP6-1 and si-LRP6-2. In the new Figure 6, provided below, they replaced panel 6D. New panel 6D contains new image for si-LRP6-2 from the original set of experiments. The authors guarantee that the correction doesn't affect the interpretation of the data or the conclusions drawn from it."}
{"text": "The authors also regret that this inadvertent error was included in the paper, even though it did not substantially alter any of the major conclusions reported in the study, and apologize to the readership for any inconvenience caused.The authors were able to locate their original data, and the corrected version of"}
{"text": "Subsequently to having performed these experiments, the authors have realized that their MCF-7 cells had become contaminated while performing the colony formation and transwell experiments. Furthermore, they were unable to reproduce the results from the Following a further investigation in the Editorial Office, it also came to light that there were other possible anomalies associated with the presentation of the tumor images in Fig. 6B and the colony formation assay data in Fig. 2C. Therefore, theos article has been retracted from the Journal; all the authors agree to this retraction. The Editor and the authors would like to apologize for any inconvenience caused."}
{"text": "The text originally read, \u201cEarly research suggests that bulk MoSThe Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "The journal retracts the 12 April 2021 article cited above for the following reasons.Following publication, concerns were raised regarding the integrity of the methodology used in the study. The authors failed to provide a satisfactory explanation during the investigation, which was conducted in accordance with Frontiers\u2019 policies.This retraction was approved by the Chief Editors of Frontiers in Pharmacology and the Chief Executive Editor of Frontiers. The authors did agree to this retraction."}
{"text": "We regret the unprofessional behavior of the authors involved.fuyan0059@sina.com>Correspondence: Yan Fu: <"}
{"text": "The German change of attitude concerning fiscal policy and the mutualisation of efforts to fight the pandemic is driven by self-interest, and as such might be structural."}
{"text": "The authors agreed with the retraction of the paper. The Editor apologizes to the readership for any inconvenience caused."}
{"text": "Sci., 2021, DOI: 10.1039/D1SC02413B.Correction for \u2018Suppressing carboxylate nucleophilicity with inorganic salts enables selective electrocarboxylation without sacrificial anodes\u2019 by Nathan Corbin  We regret that there was a minor error in the structure of the benzyl chloride in The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Euro area inflation has been rising strongly in the wake of the COVID-19 pandemic, giving rise to concerns that there could be second-round effects, with higher inflation leading to higher inflation expectations, which in turn lead to higher inflation. This could result in more persistent rises in inflation."}
{"text": "The authors regret, that the incorrect graph is showing as Figure 5a. The correct graph is shown below.The authors would like to apologise for any inconvenience caused."}
{"text": "We sincerely apologize for the inconvenience of updating the authorship. The previous authorship was Jianjia Wang, Xichen Wu, Mingrui Li, and the updated authorship is Jianjia Wang, Xichen Wu, Mingrui Li, Hui Wu, Edwin R. Hancock. Ms. Hui Wu and Professor Edwin R. Hancock should be added to the list of contributing authors. Ms. Hui Wu contributed to the formal analysis, methodology, and investigation in the original manuscript. Professor Edwin R. Hancock contributed to the supervision, methodology, and the review and editing of the manuscript. We have added them to the authorship of our paper  and upda"}
{"text": "In this paper, the phrase should be corrected as follows:For \u201cwith 50 \u03bcM ionomycin/1 \u03bcM phorbol\u201dread \u201cwith 0.5 \u03bcM ionomycin/10 nM phorbol\u201d."}
{"text": "In the original publication the email addresses of corresponding authors have not been displayed. The correct email addresses of corresponding authors are provided in this correction. Fang-Cheng Li (sjwklfc@126.com), Fei Hu (neuron111@163.com), Min-Hua Luo (luomh@wh.iov.cn)."}
{"text": "The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates."}
{"text": "Correction to: Archives of Women's Mental Healthhttps://doi.org/10.1007/s00737-021-01105-8The names of the authors were incorrect.1. Bao-Yen Luong-Thanh appears twice \u2013 please remove Yen L\u01b0\u01a1ng Thanh B\u1ea3o2. Replace Yen L\u01b0\u01a1ng Thanh B\u1ea3o with Thang Van Vo (see below)."}
{"text": "R123\u2013R144. The error relates to the Funding section on page R135.The authors and journal apologise for an error in the above paper, which appeared in volume 24 part 4, pages The original paper stated:DGO is supported by a Garvan Foundation Fellowship generously sponsored by May Dariymple.\u2019This should have stated:DGO is supported by the Garvan Research Foundation and generous donor, Mrs May Dalrymple.\u2019"}
{"text": "Sci., 2021, DOI: 10.1039/d0sc06208a.Correction for \u2018Iridium-catalyzed enantioselective olefinic C(sp The authors regret a minor error in The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "The authors regret that contact details for the corresponding authors were not provided. The corrected contact details for the corresponding authors are provided below.wuxingzhi@usts.edu.cn (Xingzhi Wu), yjy2010@suda.edu.cn (Junyi Yang), ylsong@hit.edu.cn (Yinglin Song).* Corresponding author. E-mail addresses: The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Sci. Rep.2011, 1, 2422355543Butovich et al. ) and type II diesters , which were not cited in the original paper.All conclusions in our submission are unchanged, including originaland expanded characterization data.Since the publication of theoriginal"}
{"text": "The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates."}
{"text": "The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates."}
{"text": "After having been in contact with the authors, they agreed with the decision to retract the paper. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors attention by a concerned reader that the GAPDH bands shown in the western blots in Fig. 6A were strikingly similar to data appearing in different form in other articles by different authors. Owing to the fact that the contentious data in the above article had already been published elsewhere prior to its submission to"}
{"text": "Mibyou) before Metabolic Syndrome in Mice by a Traditional Japanese Medicine (Kampo Formula) Bofutsushosan\u201d [In the article titled \u201cSuppression of Dynamical Network Biomarker Signals at the Predisease State (ushosan\u201d , the autushosan\u201d , and wer"}
{"text": "The authors regret that the following sentence should have read as: There are likely to be elements of both of these behaviours over time (Table 2).The authors would like to apologise for any inconvenience caused."}
{"text": "After publication of the original article , an erroThe incorrect authors\u2019 affiliations list is:1 Department of Oral and Maxillofacial Surgery (Zhang Zhiyuan Academician Workstation), Hainan Western Central Hospital , Hainan Branch, Danzhou, Hainan 571700, China.2 Department of Oral and Maxillofacial-Head and Neck Oncology, Ninth People\u2019s Hospital, School of Medicine, Shanghai Jiao Tong University, 639 Zhi-zao-ju Road, Shanghai 200011, China.The correct authors\u2019 affiliations list is:1 Department of Oral and Maxillofacial-Head and Neck Oncology, Ninth People's Hospital, School of Medicine, Shanghai Jiao Tong University, 639 Zhi-zao-ju Road, Shanghai, 200011, China.2 Department of Oral and Maxillofacial Surgery (Zhang Zhiyuan Academician Workstation), Hainan Western Central Hospital , Danzhou, Hainan, 571700, China.The original article has been corrected."}
{"text": "The authors regret that three of the authors were associated with the incorrect affiliations. The correct list of authors and affiliations is as shown here.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "We regret that the original version of our paper"}
{"text": "The caption for"}
{"text": "In our paper"}
{"text": "Retraction Note: BMC Anesthesiol 21, 194 (2021)https://doi.org/10.1186/s12871-021-01417-3The Editor has retracted this article because after obtaining approval for this clinical trial from the Institutional Ethical Review Committee for Clinical Trials of The First Affiliated Hospital of Sun Yat-sen University the authors made changes to the protocol without obtaining the Committee's approval. All authors agree to this retraction."}
{"text": "There is an error in the Conflict of Interest statement. The correct statement is \u201cML has received lecture and consultancy fees from Alexion, Amgen, Kyowa Kirin, Menarini, Sandoz, Takeda, UCB and Will-Pharma. JS has received lecture, consultancy fees, and conference support from Kyowa Kirin, Alexion, Eli-Lily, Ferring, Ipsen, Menarini, Novo Nordisk, Pfizer, Sandoz, and Siemens Healthcare. DT has received conference support from Novo Nordisk. NG, JLa, and KH have received consultancy fees from Kyowa Kirin. EB has received conference support from Novo Nordisk and Pfizer. CH has received conference support from Novo Nordisk and Ferring. EC has received consultancy fees from bioM\u00e9rieux, Diasorin, Fujirebio, IDS, and Menarini. PH is an employee of GlaxoSmithKline but participates in his own capacity. J-FK has received consultancy fees and conference support from Heel Belgium, Sanofi, and TRB Chemedica. KW has received conference support from Alexion, Ferring, Kyowa Kirin and Novo Nordisk. CV has received conference support from Boehringer Ingelheim. GM has received consultancy fees from Alexion, Biomarin, Kyowa Kirin, and Pfizer. EL has received consultancy fees and travel support from Kyowa Kirin, Chiesi, and Recordati. JV has received conference support and consultancy fees from Alexion, Bellco, Ferring, Medtronic, and Kyowa Kirin.The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.There should be a change to Treatment section. A 0.4 mg/kg bodyweight dose is mentioned, whereas the most recently approved dose is a 0.8 mg/kg bodyweight dose. In the subsection \u201cBurosumab\u201d in the fifth paragraph, the first sentence should read as follows: The EMA-approved dose in children is a 2-weekly s.c. injection starting 0.8 mg/kg bodyweight, increased with 0.4 mg/kg dose increments  to achieve fasting plasma phosphate concentrations in the low-normal range for age.The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated."}
{"text": "Along with the Green Deal, the von der Leyen Commission immediately started to look at how to adopt an industrial strategy that would promote EU competitiveness and support the Commission\u2019s self-assigned \u201cgeopolitical\u201d role by boosting strategic autonomy."}
{"text": "Sci., 2020, 11, 4999\u20135006, DOI: 10.1039/D0SC00317D.Correction for \u2018A straightforward approach to antibodies recognising cancer specific glycopeptidic neoepitopes\u2019 by Hajime Wakui  The authors regret that part The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "The following information is missing from the Funding statement: EAH: RO1-NS-061902, PO1-AI-077774, T32-OD-010437 , CKM: R01-NS-076894 . The publisher apologizes for the error."}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office never received any reply. The Editor apologizes to the readership for any inconvenience caused."}
{"text": "After having been in contact with the authors, they agreed with the decision to retract the paper. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors\u2019 attention by a concerned reader that the data shown in Fig. 5 and 6 were the same as those featured in another paper by different authors. Owing to the fact that the contentious data in the above article were already under consideration for publication elsewhere prior to its submission to"}
{"text": "RSC Advances article due to concerns with the reliability of the data. The images in the article were screened by an image integrity expert who raised concerns with the integrity of the western blot panels. Many of the published western blot panels share the same background, indicating that the images have been manipulated.The Royal Society of Chemistry hereby wholly retracts this In Fig 2F, 5 of the panels share the same background.In Fig 3D, all 4 panels share the same background.In Fig 5D, 3 of the panels share the same background.In Fig 6A and B, all 4 panels share the same background.The authors were asked to provide the raw data for this article, but did not respond. Given the significance of the concerns about the validity of the data, and the lack of raw data, the findings presented in this paper are not reliable.The authors have been informed but have not responded to any correspondence regarding the retraction.RSC AdvancesSigned: Laura Fisher, Executive Editor, th January 2021Date: 7"}
{"text": "The authors would like to make the following corrections about the published paper .Replacing the Institutional Review Board Statement from: The study was approved by the Institutional Review Board of Kyung-il University (KIU-1041459-202007-HR-002-01)."}
{"text": "The authors regret an errorin the version of"}
{"text": "There is an error in panel D of"}
{"text": "The Journal and Authors retract the 14 January 2021 article cited above for the following reasons provided by the Authors:Following publication, concerns were raised regarding the integrity of the images in the published figures. The authors failed to provide a satisfactory explanation during the investigation, which was conducted in accordance with Frontiers\u2019 policies.This retraction was approved by the Chief Editors of Frontiers in Oncology and the Chief Executive Editor of Frontiers. The authors agree to this retraction."}
{"text": "Regarding our paper"}
{"text": "The article titled \u201cOutcome of a Low-Cost Glaucoma Implant versus the Baerveldt Glaucoma Implant for Paediatric Glaucoma in a Tertiary Hospital in Egypt\u201d  has been"}
{"text": "In an articleThe authors apologize for the error."}
{"text": "Human Reproduction Open, 2021, hoab002, https://doi.org/10.1093/hropen/hoab002In the originally published version of this manuscript, the first name/family name order of each of the authors\u2019 names were incorrect. The author list should read: \u201cMarjan Van Reckem, Christophe Blockeel, Maryse Bonduelle, Andrea Buysse, Mathieu Roelants, Greta Verheyen, Herman Tournaye, Frederik Hes, and Florence Belva\u201d instead of \u201cVan Reckem Marjan, Blockeel Christophe, Bonduelle Maryse, Buysse Andrea, Roelants Mathieu, Verheyen Greta, Tournaye Herman, Hes Frederik, and Belva Florence\u201d. This error has now been corrected online."}
{"text": "The authors wish to make the following corrections to this paper: .Error in Figure\u201d and \u201cCurrent acquisition\u201d are reversed. The corrected  appears below.In the original publication, there was a mistake in Missing FundingAuthor would like to modify the funding section to:Funding: This work is supported by State Grid Shaanxi Electric Power Co., Shaanxi Electric Power Research Institute .The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. The original publication has also been updated."}
{"text": "Microorganisms [We have found one inadvertent error in our paper published in rganisms :The authors wish to insert this additional sentence in the Materials and Methods Section 2.4: The sequences supporting the conclusions of this article are available in the European Nucleotide Archive repository under the accession numbers PRJEB39148 and PRJEB39175.The authors wish to insert this additional sentence in the Acknowledgments section: We gratefully acknowledge Dr. G. Cantalapiedra-Hijar for his technical support, knowledge and assistance in analyzing and interpreting the natural abundance of nitrogen stable isotopes.These changes have no material impact on the conclusions of our paper. We apologize to our readers."}
{"text": "In Gang Guo,"}
{"text": "The Journal and Authors retract the 28 October 2020 article cited above for the following reasons provided by the Authors:Following publication, concerns were raised regarding data misrepresentation. The authors failed to provide a satisfactory explanation during the investigation, which was conducted in accordance with Frontiers\u2019 policies.This retraction was approved by the Chief Editors of Frontiers in Oncology and Chief Executive Editor. The authors agreed to this retraction."}
{"text": "In our paper"}
{"text": "The title should have been \u201cAssociation of Medicaid vs Marketplace Eligibility With Maternal Coverage and Access to Prenatal and Postpartum Care.\u201d This article and its supplement have been corrected.1In the Original Investigation titled \u201cAssociation of Medicaid vs Marketplace Eligibility on Maternal Coverage and Access With Prenatal and Postpartum Care,\u201d"}
{"text": "Figs"}
{"text": "Figure 2 as published. The structures of hydroxypropyl-\u03b2-cyclodextrin and sulphobutyl-\u03b2-cyclodextrin were not representing the most chemically abundant species that are formed during the reactions of chemical substitution of OH groups by 2-hydroxypropyl and sulfobutyl residues, respectively. The corrected Figure 2 appears below this text.In the original publication , there wThe authors apologise for any inconvenience caused and state that the scientific conclusions are unaffected. The original publication has also been updated."}
{"text": "The authors regret that an incorrect version of The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates."}
{"text": "The authors noticed that the E-factor (E) was calculated using a wrong Equation 2 in the original publication:The correct Equation 2 should be the following:Accordingly, the Conclusion section should be amended with the following sentence:A high AE of 74% and a low E-factor of 0.43 highlight the green character of the procedure.The authors apologize for any inconvenience caused by the originally published wrong Equation 2."}
{"text": "Dear Editor,We would like to share ideas on the publication \u201cMonitoring of cases of anosmia may help control the COVID-19 pandemic.The authors declare no conflicts of interest."}
{"text": "The following information is missing from the Funding statement: Authors would like to extend their sincere appreciation to the Researchers Supporting Project number (RSP-2020/173), King Saud University, Riyadh, Saudi Arabia."}
{"text": "The video-based free social media app, TikTok, has grown in popularity during the COVID-19 pandemic, with half of British children using Tik Tok regularly. With more than 2 billion downloads, it was the most downloaded app of 2020. Child and Adolescent Mental Health Services (CAMHS) is currently found on TikTok via the hashtag #CAMHS. The aim of this study was to explore how CAMHS is represented on TikTok through reviewing the hashtags associated with CAMHS and exploring the themes of videos with the #CAMHS hashtag.The Tik Tok app was downloaded and a search for the hashtags which featured the word #CAMHS was undertaken. A thematic analysis of the top 100 most popular uploaded videos featuring the #CAMHS was conducted. The number of likes, views and shares of the videos featuring each theme was recorded.Videos with the hashtag #CAMHS had 203.9 million views, followed by: #camhsmeme(s) totalling 43.1 million views, #camhsjokes with 21.4 million views and #camhskids, 12.5 million views. The top 100 most popular videos represented 24% of total viewed videos with the hashtag #CAMHS.The most popular recurrent themes associated with the hashtag #CAMHS in our sample were: raising awareness of mental health symptoms and management (40% of videos), reference to self-harm (27% of videos) and negative perception of CAMHS (27% of videos).Raising awareness of mental health symptoms and management had the most likes  and views . This was followed by videos with themes of reference to self-harm . The most shared themes were: reference to suicide  and videos which portrayed a theme of negative perception of CAMHS . Videos with themes of a negative perception of CAMHS also garnered 1,762,500 likes and 8,666,900 views.CAMHS is actively represented on TikTok through freely accessible unregulated videos. Videos with themes of raising awareness of mental health symptoms and management can potentially allow young people to share their experiences. Nonetheless, popular hashtags such as #CAMHSmemes and #CAMHSjokes, as well as videos featuring themes of negative perception of CAMHS, could potentially undermine the reputation of CAMHS to existing and future service users. The content of these videos should be taken seriously by CAMHS clinicians as it can potentially provide an insight into service users\u2019 experiences of CAMHS on a scale that has not been observed before. Presently these videos are not screened or modulated by the NHS CAMHS service."}
{"text": "Finally, the third sentence in the \u201cAntitumor activity of TFTD in the human gastric MKN45 intraperitoneal xenograft model\u201d subsection of the Results, towards the end of p. 642, should have read as follows (without the reference to 5FU): \u201cTFTD exhibited a significant antitumor effect compared with S-1 and CDDP in the MKN45 intraperitoneal xenograft model (P<0.01; Subsequently to the publication of the above paper, after having re-examined their raw data the authors have realized that  P<0.01; .\u201dOncology Letters for presenting them with the opportunity to publish this Corrigendum and apologize to the editor and to the readership of the journal for any inconvenience caused.The revised versions of"}
{"text": "Following publication, concerns were raised to the editorial office regarding the reliability of the scientific evidence as presented in some figures. The authors failed to provide a satisfactory explanation during the investigation, which was conducted in accordance with Frontiers' policies.This retraction was approved by the Chief Editors of Frontiers in Cardiovascular Medicine and the Chief Executive Editor of Frontiers. The authors did not agree to this retraction."}
{"text": "RSC Advances article due to concerns with the reliability of the data.The Royal Society of Chemistry hereby wholly retracts this The images in the article were screened by an image integrity expert who confirmed that some of the western blot images in this paper had been duplicated in other articles. There are no common authors between the papers.The control bands (GAPDH) in Fig. 3A of this paper are identical to the western blot control bands (GAPDH) presented in Fig. 1E of ref. The control bands (GAPDH) in Fig. 4A of this paper are identical to the western blot control bands (GAPDH) presented in Fig. 2C and Fig. 4G of ref. One of the blots in the control band (GAPDH) in Fig. 4A has also been reused as a blot in Fig. 3D of ref. The authors were asked to provide the raw data for this article but did not respond. Given the significance of the concerns about the validity of the data, and the lack of raw data, the findings presented in this paper are not reliable.The authors have been informed but have not responded to any correspondence regarding the retraction.RSC Advances.Signed: Laura Fisher, Executive Editor, th January 2021.Date: 7"}
{"text": "The authors regret that Figures 6 and 11b in ["}
{"text": "In the third column of"}
{"text": "Nature Communications 10.1038/s41467-021-25309-9, published online 17 August 2021.Correction to: Supplementary Movies\u00a0Supplementary Movie 1Supplementary Movie 2Supplementary Movie 3Supplementary Movie 4Supplementary Movie 5Description of Additional Supplementary Files"}
{"text": "The corrected graphics are given here.The authors would like to apologize for any inconvenience caused.The authors regret that theoriginal version of this article unfortunately contained a mistakein all of the graphics depicting polysaccharide derivatives with fucosylbranches (Abstract Graphic, Abstract Graphic:"}
{"text": "Scientific Reports 10.1038/s41598-021-83318-6, published online 23 February 2021Correction to: In this Article, the authors neglected to include a potential conflict of interests. The Competing Interests section should read:\u201cT.H. reported a potential conflict of interest related to patent royalties of the quantitative sequencing method for eDNA quantification. The other authors declare no competing interests.\u201d"}
{"text": "The authors would like to make the following correction to the published paper .There is a mistake in the last sentence of the second paragraph in Section 3.2 Antimicrobial Susceptibility Testing.The sentence should read \u201cARGs conferring resistance to macrolide (mreA) was found in F49\u201d.This change will not alter the conclusions drawn in the paper."}
{"text": "In"}
{"text": "The authors regret that the original version of our paper unfortunately contained some incorrect representative images. The transwell images in Figure The authors confirm that the corrections made in this erratum do not affect the original conclusions. The authors apologize for any inconvenience that the errors may have caused."}
{"text": "Bioscience Reports at the request of the Editor-in-Chief and the Editorial Board following receipt of a notification from a reader, alerting the Editorial Board to the backgrounds of the Western blots throughout the paper which unexplainedly contain the same features.This article is being retracted from The authors have been contacted in regards to the Retraction, and have not responded to the Journal's queries and the concerns raised. Given the extent of the issues raised, the Editorial Board stand by the decision to retract the article."}
{"text": "The following sentence should be added to the end of the first paragraph of the Acknowledgments section: \u201cCollection and export of fecal samples was also facilitated by the Filoha Hamadryas Project with the generous permission of the Ethiopian Wildlife Conservation Authority.\u201dVolume 4, no. 4, e00271-19, 2019,"}
{"text": "Vol. 219, No. 3 | 10.1083/jcb.201808017 | February 11, 2020The initial published version of Table S1 included a Rab1 RNAi line, P{TRiP.JF02609}attP2. That line was not tested in the RNAi screen and has been removed from the supplemental file. The authors apologize for any confusion. This error appears only in versions of Table S1 downloaded on or before January 26, 2022."}
{"text": "The authors wish to add one reference  to this On page 1, the original sentences are as follows: Progress toward new methods without cameras has been made through the use of accelerometer sensors mounted on the structure to capture floor vibration for human activities detection [13\u201315].Correction to be: Progress toward new methods without cameras has been made through the use of accelerometer sensors mounted on the structure to capture floor vibration for human activities detection [13\u201316].The sequential references originally in the paper  will shift by one .The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. The original article has been updated."}
{"text": "J Clin Exp Dent. 2021 Apr1;13(4):e418-21), there is an error in the authors of the manuscript. Thecorrect author list is: Pablo Garrido-Mart\u00ednez, Juan-Francisco Pe\u00f1a-Cardelles, NorbertoQuispe-L\u00f3pez, Jos\u00e9-Juan Pozo-Kreilinger, Germ\u00e1n Esparza-G\u00f3mez, N\u00e9stor Montesdeoca-Garc\u00eda,Jos\u00e9-Luis Cebri\u00e1n-Carretero.In this article by Garrido-Mart\u00ednez P and colleagues ("}
{"text": "Penicillium chrysogenum to Penicillium rubens. However, the Seventeenth International Botanical Congress  , as was outlined in previous papers , project KU 517/15-1."}
{"text": "Adv. Sci. 2020, 7, 200054210.1002/advs.202000542DOI: In the originally published article, one affiliation of Chang Liu was missing. Please find the complete affiliations here:Dr. S. Chen, Dr. W. Zhang, C. Sun, M. Song, S. Liu, M. Xu, Prof. C. LiuState Key Laboratory of Natural Medicines, School of Life Science and TechnologyChina Pharmaceutical UniversityNanjing 211198, ChinaDr. X. Zhang, Prof. L. LiuDepartment of GeriatricsFirst Affiliated Hospital with Nanjing Medical UniversityNanjing 210029, ChinaProf. C. LiuState key Laboratory of Pharmaceutical BiotechnologyNanjing UniversityNanjing 210046, Chinachangliu@cpu.edu.cnE\u2010mail: The authors apologize for any inconvenience this may have caused."}
{"text": "The authors wish to make following corrections in this paper .Shih-Chen Chen is included as a corresponding author in the updated publication. There was an error in the original publication. In the first paragraph of page 7, in the sentence \u201cThe LCE of NP-GaN structure is found to be enhanced by 66.2% for green QD and 124.0% for red QD\u201d, the 124.0% should be changed to 52.7%. In Figure 5c,f, the LCE of the red QD film and red NPQD are 62.9% and 96.1%. As a result, the enhancement is 52.7%, not 124.0%.This change does not affect the scientific results or conclusions in the original published paper.The authors would like to apologize for any inconvenience caused to the reader by making this change."}
{"text": "Sci., 2020, 11, 6085\u20136096, DOI: 10.1039/D0SC02066D.Correction for \u2018Mechanistic details of the cobalt-mediated dehydrogenative dimerization of aminoquinoline-directed benzamides\u2019 by Li-Ping Xu  The authors regret the omission of one of the authors, Manjaly J. Ajitha, from the original manuscript. The corrected list of authors and affiliations for this paper is as shown above.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "The authors apologize that the original version of this paper unfortunately contained two incorrect figures and a terminology error due to negligence in drafting and proofreading. Firstly, in Section A of Figure 2, the DAPI and Merge images of the control group were not presented correctly. Secondly, Section B and Section C of Figure 7 were reversely marked. In addition, the term MI-LV-shPHD2-BMSC in the last paragraph of the Results section should be \u201cMI-LV-GFP-BMSC\u201d (Page 4977).The authors apologize for any inconvenience these errors may have caused. Luckily they have no influence on the conclusion drawn by the study. The correct figures are shown below."}
{"text": "The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates."}
{"text": "In \u201cElectronic Video Consent to Power Precision Health Research: A Pilot Cohort Study\u201d :e29123) the authors noted six errors.The title of the originally published article appeared as follows:Electronic Video Consent to Power Precision Research: A Pilot Cohort StudyIn the corrected version, the title has been revised to:Electronic Video Consent to Power Precision Health Research: A Pilot Cohort StudyIn the original version, author Liliana Johansen's name was displayed incorrectly as follows:Lilliana JohansenIn the revised version, it has been corrected as follows:Liliana JohansenIn the originally published paper, Affiliation 1 appeared as follows:UCLA Center for SMART Health, Clinical Translational Science Institute, David Geffen School of Medicine at UCLA, Los Angeles, CA, United StatesIn the revised version, it has been revised to:UCLA Center for SMART Health, Clinical and Translational Science Institute, David Geffen School of Medicine at UCLA, Los Angeles, CA, United StatesIn the originally published paper, Affiliation 2 appeared as follows:David Geffen UCLA School of Medicine, Los Angeles, CA, United StatesIn the revised version, it has been revised to:David Geffen School of Medicine at UCLA, Los Angeles, CA, United StatesIn the originally published paper, Affiliation 4 appeared as follows:Office of Clinical Research, Clinical and Translational Science Institute, David Geffen School of Medicine at UCLA, Los Angeles, CA, United StatesIn the revised version, it has been revised to:Embedded Clinical Research and Innovation Unit, CTSI Office of Clinical Research, Los Angeles, CA, United StatesIn the originally published paper, the following email address of the corresponding address was provided:arashnaeim@gmail.comIn the revised version, it has been changed to:anaeim@mednet.ucla.eduThe corrections will appear in the online version of the paper on the JMIR Publications website on October 21, 2021, together with the publication of this correction notice. Because this was made after submission to PubMed, PubMed Central, and other full-text repositories, the corrected article has also been resubmitted to those repositories."}
{"text": "Horiz., 2022, DOI: 10.1039/d1mh01343b.Correction for \u2018Bipolarons rule the short-range terahertz conductivity in electrochemically doped P3HT\u2019 by Demetra Tsokkou  The authors regret that the wrong version of The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Bioscience Reports at the request of the authors following receipt of a notification from a reader, alerting the Editorial Office to unusual data presented in Figures 2 and 3.This article is being retracted from The Editorial Office requested the raw data from the authors and this has not been provided. The authors wish to retract the article. The Editor-in-Chief and Editorial Board agree with the Retraction."}
{"text": "The withdrawal has been agreed because the article has been submitted and approved for publication by Emad Karrar without consent by several co\u2010authors.Withdrawal: Ahmad N, Hussain M, Sameen A, et al. Extraction and enrichment of maize bran cell wall in bread and its textural, and microbial assessment. Food Sci Nutr. 2021;00:1\u20108."}
{"text": "Despite all the difficulties inherent to our political organisation, the European Union has taken a bold step by doubling the EU budget for the next six years with the NGEU fund."}
{"text": "The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates."}
{"text": "Sci., 2020, 11, 9904\u20139909, DOI: 10.1039/D0SC02646H.Correction for \u2018Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors\u2019 by Karen Sargsyan  The authors regret the omission of three of the authors, Jian-Jong Liang, Chen-Che Liao and Yi-Lang Lin, from the original manuscript. The corrected list of authors and affiliations for this paper is as shown above.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Erratum zu:Bundesgesundheitsbl 202110.1007/s00103-021-03338-5In der urspr\u00fcnglichen Originalfassung des Artikels wurde leider Abb."}
{"text": "Bioscience Reports at the request of the Editorial Board following receipt of a notification from a reader, alerting the Editorial Office to duplications in the Western blots of Figure 2D and flow-cytometry in Figure 3A which have been published in several other publications by different authors.This article is being retracted from The authors contacted the Editorial Office to request a Correction however, given the extent of the issues raised, the Editorial Board stand by the decision to retract the article. The authors disagree to the Retraction."}
{"text": "Consequently, owing to a lack of confidence in the presented data, the authors requested that this paper be retracted from the Journal.Following the publication of this paper, an interested reader drew the authors\u2019 attention to the fact that several of the tumour images shown in Fig. 6B were strikingly similar to images that had appeared in another paper by different authors published at around the same time. The authors also admitted that the The Editor was in agreement that the paper should be retracted. All authors agree with the retraction of this article, and the Editor apologizes to the readership for any inconvenience caused."}
{"text": "The authors agree with the decision to retract the paper. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors' attention by a concerned reader that the tumor images shown in Fig. 6B bore unexpected similarities to data appearing in different form in other articles by different authors. In addition, there were potential anomalies associated with the cell migration assay data shown in Fig. 2E. Owing to the fact that some of the contentious data in the above article had already been published elsewhere, or were already under consideration for publication, prior to its submission to"}
{"text": "Figs"}
{"text": "Abbas Masoom, helping her mother publish the Danesh newspaper. Another document (Morteza Gholi Khan Hedayat (1856\u20131911 AD), the first chairman of the Iranian parliament and minister of \u201cEducation and Endowments and Public Benefits\u201d in Qajar dynasty, has issued the permission for publication of Danesh newspaper by Lady Dr. Kahhal on August 31, 1910. The last document (In a previously published paper , we had document  is a letdocument  is the l There is no conflict of interest. The authors would like to thank the National Library and Archives of the Islamic Republic of Iran for the cooperation in providing the documents."}
{"text": "We find that the supersymmetric intersections govern many aspects of the theory of W-algebras, including degenerate modules, the Miura transform and Coulomb gas constructions. We give an algebraic interpretation of the Pandharipande-Thomas box counting in \u2102"}
{"text": "Vol. 218, No. 4 | 10.1084/jem.20202187 | January 19, 2021The authors regret that the amino acid sequence of one of the T epitopes in The error appears in print and in PDFs downloaded before September 30, 2021."}
{"text": "Sci., 2020, 11, 9703\u20139711, DOI: 10.1039/D0SC01122C.Correction for \u2018Rational design of a \u201cdual lock-and-key\u201d supramolecular photosensitizer based on aromatic nucleophilic substitution for specific and enhanced photodynamic therapy\u2019 by Kun-Xu Teng  The authors regret an error in Additionally, there was a minor error in The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "N-aryl pyrazoles\u2019 by Tung T. Nguyen et al., RSC Adv., 2021, 11, 9349\u20139352, DOI: 10.1039/D1RA00975C.Correction for \u2018Cobalt-catalyzed, directed arylation of C\u2013H bonds in  All mentions of CeSO4 in the paper and ESI should be read as the commercially available cerium(iv) sulfate, Ce(SO4)2. The conclusions of the paper have not been affected.The authors regret that due to a typing error in the manuscript, the compound Ce(SOThe Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Furthermore, they apologize to the readership for any inconvenience caused.The revised versions of"}
{"text": "The Editorial Office has been made aware of potential issues surrounding the scientificvalidity of this paper, hence has issued an expression of concern to notify readerswhilst the Editorial Office investigates."}
{"text": "We regret the unprofessional behavior of the authors involved.joethomas5725@gmail.com>Correspondence: Wenhao Zhang: <"}
{"text": "Consequently, the authors no longer feel confident about the reported results, and consider the conclusions of this study to be unreliable.The Editor has granted the authors\u2019 request that the paper be retracted, and all the named authors agree to this retraction. The authors sincerely apologize for their errors, and regret any inconvenience caused."}
{"text": "Binsley  The authors regret that the following items are incorrect in the original article.\u22121 as opposed to kg m\u22121 s\u22121). This impacts Firstly, the units of viscosity are incorrectly labelled throughout the paper (listed as kg msQ and vpeak was found to be \u223c775/2104, which is in fact a value taken from an intermediate step, which was also miscalculated. The correct ratio between Q and vpeak should be stated as \u223c0.430 \u00d7 10\u22126. Due to the miscalculation included, the flow rates represented in the abstract and Additionally, in section 2.6, a constant ratio between Please find the corrected figures below.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "The threat of an epidemic narrows the scope for political competition. As Fidesz\u2019s position within the EU has weakened significantly with the withdrawal from the European People\u2019s Party, and the COVID-19 crisis is generating serious social tensions, the questions seem to be more open in the spring of 2022 than during the previous three elections."}
{"text": "Scientific Reports 10.1038/s41598-021-00945-9, published online 02 November 2021Retraction of: The Authors have retracted this Article.in Figure\u00a01C, the middle panel in the left column for the invasion assay overlaps partially with the middle panel in the right column for the migration assay;in Figure\u00a05D, the following four panels overlap partially: migration control, invasion control, migration 50uM and invasion 50uM.After publication the Authors became aware of anomalies in two of the figures. Specifically:All Authors agree with this retraction and its wording."}
{"text": "Cell Death DiscoveryCorrection to: 10.1038/s41420-019-0203-5 published online 5 August 2019Following publication, an error was noticed in Fig. In the Fig. The authors apologise for any inconvenience caused by these errors."}
{"text": "Rohiwal et al., RSC Adv., 2021, 11, 4308\u20134317, DOI: 10.1039/D0RA09301G.Correction for \u2018Self-assembly of bovine serum albumin (BSA)\u2013dextran bio-nanoconjugate: structural, antioxidant and  The authors regret that the affiliations for Gaber El-Saber Batiha were incorrectly shown in the original manuscript. The corrected list of affiliations is as shown above.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "GENETICS, 2021, 217(3), https://doi.org/10.1093/genetics/iyab004In the originally published version of this paper, on page 20 the first line of data in the \u201cChemoreceptors\u201d column of Table 3 has now been changed to \u201cSRBC-64, SRBC-66\u201d. It originally read \u201cSRG-64, SRG-66\u201d.All other results and conclusions of the manuscript remain unchanged."}
{"text": "The editor and the author would like to make the following corrections about the published paper . The chaReplacing the sentence in \u201cSection 3. Results\u201d in page of 7:1.596).All 550 questionnaires were returned. Among these 550 questionnaires, 328 were valid and thus retained .All 550 questionnaires were returned. Among these 550 questionnaires, 328 were valid and thus retained (valid response rate: 59.6%; remaining landscape socialization points:"}
{"text": "Labels in Volume 13, issue 1, e03252-21, 2021,"}
{"text": "In: Vijay S, Sharma M, Misri J, Shome BR, Veeraraghavan B, et al. An integrated surveillance network for antimicrobial resistance, India. Bull World Health Organ. 2021 Aug 1;99(8):562\u201371, On page 563,"}
{"text": "This work is an updated and extended version of the early local presentation made at KOREA INFORMATION SCIENCE SOCIETY conference by the same authors: \"Bike Sharing Demands Prediction based on GCN\", Proceedings of the KISS Conference p832-834, 2018."}
{"text": "The authors would like to make the following correction to the published paper :Salmonella spp. The primers reported in the original version of the manuscript targeted the fimA as well, but they were not the ones used for the detection of Salmonella spp. The correct oligonucleotides designed in this study, targeting the fimA gene, are fimA F: CAC TAA ATC CGC CGA TCA AAC G and fimA R: TTC AGG ACG ATG GAG AAA GGC.There is a mistake in the primer sequences provided in Table 2 for the detection of"}
{"text": "This Retraction follows an Expression of Concern relating to this article previously published by Portland Press.Bioscience Reports at the request of the Editor in Chief and the Editorial Board following receipt of a notification from a reader, alerting the Editorial Board to duplication in Figure 5F. The Editorial Office has also identified evidence of potential image manipulation in this Figure.This article is being retracted from The authors were contacted regarding the concerns raised and provided a replacement Figure 5F, however given that the original image showed signs of potential manipulation the Editorial Board stands by the decision to retract. The authors do not agree that the images were deliberately manipulated, but agree to the retraction."}
{"text": "DOI: 10.1039/D1RA06994B.Correction for \u2018The binary aluminum scandium clusters Al The corrected list of affiliations is as shown above.The authors regret that the one of the affiliations (affiliation The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "An additional affiliation is missing for the third author. Karina Motta Melo is also affiliated with Universidade Federal Rural da Amaz\u00f4nia, Campus Tom\u00e9 A\u00e7u, Tom\u00e9 A\u00e7u, Par\u00e1, Brazil.There are errors in Figs There is an error in the"}
{"text": "Journal of Power Sources1 without being cited and without permission from the publisher to reproduce the image.The authors regret that Fig. 6A was re-used from an article published in the The authors have now received the permission to reuse the image and the corrected caption is shown below:g-G (B). (a). Reproduced from Hadi Hosseini et al., with permission from Elsevier, 2014.Fig. 6 HR-TEM images of graphene oxide (A), and Au NP@SIL-The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates."}
{"text": "Sci., 2019, 10, 3535\u20133542.Correction for \u2018Rapid room temperature synthesis of red iridium( Journal of Materials Chemistry C1 and Materials Chemistry Frontiers,2 which should have been cited in this Chemical Science paper. The authors understand that they should have notified the journal\u2019s editors about the related manuscripts when this Chemical Science paper was under review.This correction is being published to draw the readers\u2019 attention to the authors\u2019 closely related papers, published at a similar time in iii) complexes that contain a four membered ring based on the same Ir\u2013S\u2013C\u2013S backbone. However, the complexes reported in each paper have different cyclometalated moieties and/or different dithiocarbamate derivatives as the main ligands and ancillary ligands, respectively.All three papers report cyclometalated iridiumphenyl)quinazoline as the main ligand and three dithiocarbamate derivatives as ancillary ligands. In In this iii) complexes with similar structures, these materials show different photophysical properties and device performances. However, Chemical Science paper.Therefore, although all the papers reported iridium(The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "The authors wish to make the following corrections to the published paper . They shMissing FundingPostgraduate Research & Practice Innovation Program of Jiangsu Province, SJCX20_1116 to Henan Zhang and Zhibin Ling was not included. The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated.In the original publication, the funder"}
{"text": "Due to a production error, the equal contribution of Zeyu Chen and Lanqing Yang was not included. The publisher apologizes for this mistake."}
{"text": "Soc. Rev., 2019, 48, 937\u2013961, DOI: 10.1039/C8CS00193F.Correction for \u2018Strong light\u2013matter interactions: a new direction within chemistry\u2019 by Manuel Hertzog  The authors regret that eqn (16) was missing a factor of \u00bd. The corrected equation isThe Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "This change is marked in bold in the updated table below.In the original published version of the paper of Giallauria Table 1. Characteristics of the trials includedFigureFigureFigureFigureThere were also changes noted in"}
{"text": "There is an error in"}
{"text": "Sci., 2021, DOI: 10.1039/d1sc00127b.Correction for \u2018Light-induced assembly and disassembly of polymers with Pd The correct version of The authors regret that the structure of the cyclised photoacid in The authors also regret that the direction of the reaction arrows between the open and closed form of the photoacid in Fig. S32 of the ESI was previously incorrect, and unrelated ref. S12\u2013S14 about crystallographic work were listed. Fig. S32 has now been corrected in the ESI, and the previous ref. S12\u2013S14 have been removed.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Sci., 2020, 11, 27\u201336.Correction for \u2018Influenza as a molecular walker\u2019 by P. H. (Erik) Hamming  The authors regret that incorrect details were given for ref. 70 in the original article. The correct version of ref. 70 is given below as The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "In"}
{"text": "Ghule  The authors regret that an incorrect version of The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates."}
{"text": "In the originally published version of this manuscript, there was an error in thetitle. The title referred to: \u201cSystemic sclerosis-related digitalcalcinosis; a pilot study of cutaneous oxygenation and perfusion\u201d. This hasnow been corrected to online to: \u201cSystemic sclerosis-related digital ulcers;a pilot study of cutaneous oxygenation and perfusion\u201d."}
{"text": "Following publication of the original article , the autThe sentence currently reads:Locked twins is a rare and hazardous obstetric complication, which occurs in approximately 1:100 twin pregnancies.The sentence should read:Locked twins is a rare and hazardous obstetric complication, which occurs in approximately 1:1000 twin pregnancies.The sentence currenty reads:Locked twins is a rare, hazardous obstetric complication, which occurs in approximately 1:100 twin pregnancies , 3.The sentence should read:Locked twins is a rare, hazardous obstetric complication, which occurs in approximately 1:1000 twin pregnancies , 3.The original article  has been"}
{"text": "The journal retracts the 08 November 2019 article cited above.Following publication, concerns were raised regarding the integrity of the images in the published figures. The authors failed to provide a satisfactory explanation during the investigation, which was conducted in accordance with Frontiers' policies.This retraction was approved by the Chief Editors of Frontiers in Molecular Neuroscience and the Chief Executive Editor of Frontiers. The authors did not agree to this retraction."}
{"text": "Dear Editor,Although we appreciate the author's attention to our paper (Ali & Amin,\u00a0The authors are correct that de\u2010attenuated correlation may improve the energy\u2010adjusted agreement, but this was beyond our study methodology. However, the authors misinterpreted our study findings. The authors selectively picked up the weighted kappa value of \u2018poor\u2019 for four nutrients but ignored the \u2018slight\u2019 and \u2018fair\u2019 categories of agreements for other micronutrients (Landis & Koch,\u00a0The authors declare that they have no conflicts of interest."}
{"text": "All the authors agree to the publication of the authors, and they apologize to the readership for any inconvenience caused.A corrected version of"}
{"text": "The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates."}
{"text": "This article  has beenThe decision to retract has been taken in agreement with the authors and approved by the Editor-in-Chief.Nanomaterials for any inconvenience caused. To ensure the addition of only high-quality scientific work to the field of scholarly publication, this paper [The Nanomaterials Editorial Office and authors apologize to the readers of is paper  is retra"}
{"text": "S. aureus adhesion on pristine PMMA, HA-5% lysozyme in The authors regret to inform that, the representative images of waterborne The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "N-acyl amidines to amidoximes: a convenient synthetic approach to molnupiravir (EIDD-2801) from ribose\u2019 by Ajaz Ahmed et al., RSC Adv., 2021, 11, 36143\u201336147, DOI: 10.1039/D1RA06912H.Correction for \u2018Conversion of  The corrected affiliation is shown here.The authors regret that affiliation The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "The authors wish to make the following corrections to this paper :According to our previous researches , in a DLSC, detonation waves that propagate in the LE are no longer centered at the From the geometric relationship in In the subsequent research process, we found that there was no need to calculate the values of R is the curvature radius of the liner):For the calculation of the incident angle of the detonation wave, when When From the geometric relationship in Since this part only introduces the collapsing process of the liner in the figure, it has not been theoretically calculated and this part has no influence on the main research ideas and contents of the paper. The modification in this section does not affect the subsequent numerical simulation analysis and experimental results.We apologize for the inconvenience caused to the readers by our mistakes."}
{"text": "In our paper"}
{"text": "The following funding disclosure was left out of the manuscript during the submission and production process. The original manuscript has been updated to include this statement.Research reported in this publication was supported by the National Library of Medicine of the National Institutes of Health under Award Number G08LM013198. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health."}
{"text": "Vol. 218, No. 11 | 10.1084/jem.20210479 | September 21, 2021The authors regret that the legends to The errors appear only in PDFs downloaded before September 27, 2021."}
{"text": "The authors wish to correct the following in this paper .1\u00a0Graduate Institute of Life Sciences, National Defense Medical Center, Taipei 114, Taiwan3\u00a0School of Public Health, National Defense Medical Center, Taipei 114, TaiwanThe fourth author, Ching-Huang Lai, should be affiliated with:The authors would like to apologize for any inconvenience caused to the readers by this change."}
{"text": "After having been in contact with the authors, they agreed with the decision to retract the paper. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors\u2019 attention by a concerned reader that certain of the Transwell cell migration assay data shown in Figs. 4B and 5B were strikingly similar to data appearing in different form in other articles by different authors. Owing to the fact that the contentious data in the above article had already been published elsewhere, or were already under consideration for publication, prior to its submission to"}
{"text": "The critical relations are the building blocks of the relational clone of a relational structure with respect to the relational operations intersection and direct product. In this paper we describe the critical relations of crowns. As a consequence, we obtain that the subpower membership problem for any crown is polynomial-time solvable."}
{"text": "On behalf of all authors, I would like to reply as follows:"}
{"text": "The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates."}
{"text": "In"}
{"text": "Biol., 2021, 2, 713\u2013724. DOI: 10.1039/d1cb00007a.Correction for \u2018Antibody recruiting molecules (ARMs): synthetic immunotherapeutics to fight cancer\u2019 by Silvia Achilli  The authors regret mistakes in the structures depicted in The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Sci., 2020, DOI: 10.1039/d0sc04044d.Correction for \u2018Direct synthesis of the organic and Ge free Al containing BOG zeolite (ITQ-47) and its application for transformation of biomass derived molecules\u2019 by Qintong Huang  In the original manuscript, the affiliations of authors Anmin Zheng and Avelino Corma were displayed incorrectly. The corrected affiliations are as displayed above.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Dear Editor,I would like to share ideas on the publication \u2018Ivermectin: potential role as repurposed drug for COVID-19\u2019 . Ivermec"}
{"text": "Chem., 2021, 12, 1391\u20131401, DOI: 10.1039/D1MD00110H.Correction for \u2018Truncated S-MGBs: towards a parasite-specific and low aggregation chemotype\u2019 by Daniel P. Brooke  The authors regret that they omitted to include the following statement at the end of the Acknowledgements section: this work is based on research funded in part by the Bill & Melinda Gates Foundation (Investment ID OPP1093639) and with UK aid from the UK Government (Project 300504) through GALVmed. The findings and conclusions contained within are those of the authors and do not necessarily reflect positions or policies of the Bill & Melinda Gates Foundation or the UK Government.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "DOI: 10.1039/C3RA23176CCorrection for \u2018Nanochannel conduction in piezoelectric polymeric membrane using swift heavy ions and nanoclay\u2019 by Karun Kumar Jana  This correction does not alter the conclusions presented in this The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "After reviewing these requests, the Editors feel the findings of the manuscript can no longer be relied upon and have decided to retract the paper. The corresponding author has agreed to the retraction."}
{"text": "Sci., 2021, DOI: 10.1039/d1sc01178b.Correction for \u2018Unexpected formation of 1,2- and 1,4-bismethoxyl Sc In the 13C NMR spectrum of 1, the peaks corresponding to the sp3 carbons of the fullerene cage and the methoxy groups were wrongly identified. The correct version of The authors regret a mistake in 13C NMR spectrum in the Results and discussion section should therefore read: Resonance for the two sp3Ih-C80 cage-carbons bonded to the OCH3 groups appears at 74.49 ppm, while the peak for the two sp3 OCH3 carbons appears at 53.76 ppm.The description of the 13C NMR results in the Experimental section should therefore read: 74.49 , 53.76 ppm .The description of the These corrections do not influence any conclusions of the original paper.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "The correct corresponding author is Sonoko D. Bellingrath-Kimura. Sonoko D. Bellingrath-Kimura\u2019s email address is: There are errors in the Author Contributions. The correct contributions are:Conceptualization: Ei Phyu WinData curation: Ei Phyu WinFormal analysis: Ei Phyu WinFunding acquisition: Ei Phyu WinInvestigation: Ei Phyu WinMethodology: Ei Phyu WinProject administration: Kyaw Kyaw WinResources: Ei Phyu WinSoftware: Ei Phyu WinSupervision: Sonoko D. Bellingrath-Kimura, Aung Zaw OoValidation: Sonoko D. Bellingrath-Kimura, Aung Zaw OoVisualization: Sonoko D. Bellingrath-Kimura, Aung Zaw OoWriting\u2013original draft: Ei Phyu WinWriting\u2013review & editing: Sonoko D. Bellingrath-Kimura, Aung Zaw Oo"}
{"text": "Jon Pines FRSEditor-in-Chief, Open Biology"}
{"text": "In , Wei\u2010guaThe authors' names and the numerals linking their affiliations should thus appear as follows in the author by\u2010line:1,2, Yan\u2010bin Zhu1, Jiang\u2010tao Ma1, Xiao\u2010li Yan1, Ying\u2010ze Zhang1.Wei\u2010guang ZhaoThe reordered and renumbered affiliations should appear as follows:1Department of Trauma Emergency Center, The Third Hospital of Hebei Medical University, Orthopaedics Research Institute of Hebei Province, Key Laboratory of Biomechanics of Hebei Province, Shijiazhuang and 2Department of Orthopaedic Surgery, HanDan Central Hospital, HanDan, China.The authors apologize for the error and any inconvenience it may have caused."}
{"text": "Retraction Note: J Exp Clin Cancer Res 36, 162 (2017)https://doi.org/10.1186/s13046-017-0628-8Figure 1a: the panels for LC3B/WHO III and ATG5/WHO IV appear to be identicalFigure 5b: the lanes for Smad and TFG-B2 appear to be identicalFigure 7e: the panels for TGF-B2/LY2157299 and ATG7/LY2157299+CQ appear to be identicalFigure 7e: the panels for ATG5/LY2157299+CQ and MMP9/LY2157299+CQ appear to be identicalFigure 7e: the panels for ATG7/LY2157299 and MMP2/LY2157299+CQ appear to be identicalFigure 7e: the panels for TGF-B2/Con and MMP2/LY2157299 appear to be identicalThe authors have retracted this article. Concerns were raised regarding a number of figures, specifically;In addition, the authors have stated they found some additional errors in Figs 5c, 5d and 5j. Additionally, the authors have stated they have reviewed the original data and images that should have been included in this article, but given the extent of the misplaced figures, they have agreed to retract the article. The authors would like to apologize for any inconvenience caused by this retraction.All authors agree to this retraction."}
{"text": "P. Adarsh Krishna  The authors regret that the first sentence in Section 2 (Occurrence and isolation) contained errors. The correct sentence is the following:Psoralea corylifolia L. Medik  by a team of scientists at the National Chemical Laboratory (NCL), Pune, India.\u201d\u201cBakuchiol (Syn. Chiba) was first extracted from the seeds of The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "We would like to share our ideas on the paper \u201cEvaluating Voice Assistants\u2019 Responses to COVID-19 Vaccination in Portuguese: Quality Assessment\u201d . In addiSer\u00f3dio Figueiredo et al  assessed"}
{"text": "After having been in contact with the authors, they agreed with the decision to retract the paper. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors\u2019 attention by a concerned reader that certain of the western blotting data shown in Fig. 3C, 4D, 5A and 6D bore unexpected similarities to data appearing in different form in other articles by different authors. Owing to the fact that the contentious data in the above article had already been published elsewhere, or were already under consideration for publication, prior to its submission to"}
{"text": "In the article titled \u201cApplication of 3D Printing-Assisted Articulating Spacer in Two-Stage Revision Surgery for Periprosthetic Infection after Total Knee Arthroplasty: A Retrospective Observational Study\u201d , some of"}
{"text": "After having been in contact with the authors, they agreed with the decision to retract the paper. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors\u2019 attention by a concerned reader that certain of the cell cycle assay data shown in Figs. 2D and 5C were strikingly similar to data appearing in different form in other articles by different authors. Owing to the fact that the contentious data in the above article had already been published elsewhere, or were already under consideration for publication, prior to its submission to"}
{"text": "This article published in Cell J (Yakhteh), Vol 23, No 2,2021, on pages 191-198, corresponding author andcorresponding address were changed based on authors\u2019request. The authors would like to apologies for anyinconvenience caused."}
{"text": "Zingiber officinale var. rubrum (red ginger) is widely used in traditional medicine in Asia. Unlike other gingers, it is not used as a spice in cuisines. To date, a total of 169 chemical constituents have been reported from red ginger. The constituents include vanilloids, monoterpenes, sesquiterpenes, diterpenes, flavonoids, amino acids, etc. Red ginger has many therapeutic roles in various diseases, including inflammatory diseases, vomiting, rubella, atherosclerosis, tuberculosis, growth disorders, and cancer. Scientific evidence suggests that red ginger exhibits immunomodulatory, antihypertensive, antihyperlipidemic, antihyperuricemic, antimicrobial, and cytotoxic activities. These biological activities are the underlying causes of red ginger\u2019s therapeutic benefits. In addition, there have been few reports on adverse side effects of red ginger. This review aims to provide insights in terms the bioactive constituents and their biosynthesis, biological activities, molecular mechanisms, pharmacokinetics, and qualitative and quantitative analysis of red ginger. Zingiber officinale, consisting of seven species, is mainly distributed in Asia , of which two are accepted names and six are synonyms. Based on the size and color of the rhizome, common ginger can be categorized into three varieties: giant ginger or white ginger , small white ginger or emprit ginger Rhizome , and red ginger  [Zingiber officinale Roscoe var. rubrum. Its synonyms are Zingiber officinale Roscoe var Sunti Val., Zingiber amomum L., Zingiber cholmondeleyi (F.M. Bailey) K. Schum., Zingiber missionis Wall., Zingiber officinale var. macrorhizonum Makino, Zingiber officinale var. rubens Makino, and Zingiber sichuanense. It is red, with a yellow to pink cross section on the outside of the rhizomes, while the base of the leaf shoot is red. It is an annual plant that grows up to 50\u2013100 cm high. The rhizomes are thick and reddish-brown. It is morphologically similar to common ginger. It is smaller and more pungent than common ginger. The leaves are narrow and lancet-shaped, 5\u201325 cm in length and 8\u201320 mm in width. The plant has an ovoid-shaped composite that emerges from the rhizomes, with a stem length of 10\u201325 cm and small leaves at the base of the flower. The corollas are funnel-shaped, 2\u20132.5 cm long, and dark purple with creamy yellow spots. The petals are small, tubular, and tridentate. Unlike common ginger, its petiole is reddish, and the lip is scarlet red [There is a taxonomic challenge when identifying the correct species as many synonyms are reported for ginger. There are eight plant names for the species  rubrum) . Red ginrlet red . Red ginZingiber officinale var. rubrum\u201d, \u201cHalia Bara\u201d, and \u201cred ginger\u201d. Only articles published in English are included in this review. A few additional references from the web that were deemed useful for the completion of this review article were included.The Pubmed, Scopus, and Web of Science databases were used to collect the information on red ginger. The keywords used were \u201cZingiber officinale var. rubrum. This review aims to provide an exhaustive summary of the (1) traditional uses, (2) chemical constituents and their biosynthesis, (3) bioactivities and molecular mechanisms, (4) analysis and quality control, and (5) medicinal products. Research gaps in the literature are identified and we have suggested future research opportunities. Perspectives on further improving the medicinal value of red ginger are provided.To the best of our knowledge, this review article is the first on The chemical composition of red ginger is complex, containing about 169 chemical constituents ,11,12,13The chemical structures of constituents and their respective compound classes are recorded in The vanilloids are biosynthesized from the amino acid phenylalanine, as shown in Red ginger is reported to possess a wide range of biological and pharmacological activities. In traditional medicine, it is used for treating headaches, indigestion, nausea, vomiting, and cancer. In addition, it is widely used to treat autoimmune diseases , hypertePseudomonas aeruginosa, Staphylococcus aureus, and Bacillus subtilis. The rhizome oil was moderately active against Bacillus licheniformis, Bacillus spizizenii, Staphylococcus aureus, and Escherichia coli [Many studies have reported the antimicrobial and antifungal effects of ethanol and methanol extracts of red ginger ,64. Red Candida albicans, Staphylococcus aureus, and Streptococcus mutans; therefore, the combinations may help treat orals infections. Another study found that the combination of nisin and red ginger essential oil had a synergistic effect against Bacillus cereus [Red ginger extract has been used as an auxiliary medicine for treating oral infections. Sukandar et al.  investigs cereus . Studiess cereus . Irawan s cereus  have incs cereus  optimize\u03b2-caryophyllene has predominant antimicrobial activity [Bacillus cereus > Escherichia coli > Salmonella typhimurium > Pseudomonas aeruginosa [Staphylococcus aureus > Escherichia coli > Aspergillus niger > Bacillus cereus > Pseudomonas fluorescens > Salmonella typhimurium. In contrast, the fresh red ginger extract showed stronger activity against Staphylococcus aureus and E. coli [Streptococcus mutans is more potent than that of common ginger [The primary antimicrobial compounds in red ginger are monoterpenes, of which activity . The majactivity . The antruginosa  and Stap E. coli . The antn ginger . Many st2B activity and pain sensitization [The analgesic activity of red ginger is comparable to that of aspirin . Neuropatization . Anothertization ,73. Red tization . Camphentization ,35.Red ginger inhibits saccharide hydrolyzing enzymes and, thus, can be used for controlling hyperglycemia in type 2 diabetic patients. Safithri et al.  found thOboh et al.  reportedMany studies have confirmed that chronic inflammation is the underlying cause for many diseases such as allergies, atherosclerosis, cancer, diabetes, infection, obesity, and neurodegeneration ,78. Red Many studies have confirmed red ginger\u2019s free radical scavenging activity in different test models ,44,45. Tortho-dihydroxy group on the aromatic ring in vanilloids play a significant role in the anticancer activity [The anticancer activity of red ginger is mainly due to certain pungent vanilloids . Severalactivity . Vimala activity  reportedactivity ,47. Studactivity  reportedactivity . Multiplactivity ,50,51 (Fw/v) inhibited the actions of Angiotensin-I converting enzyme (ACE), iron(II) ion, and sodium nitroprusside (SNP)-induced lipid peroxidation in rats\u2019 hearts via reducing malondialdehyde levels. The activity of red ginger in this respect is more remarkable than that of common ginger [2+ release from intracellular stores. The vanilloids are attributed to the antihypertensive activity of red ginger.The antihyperlipidemic, antihypertensive, and antihypercholesterolemic mechanisms of action are as shown in n ginger . The antn ginger . Razali n ginger  demonstrIt is well known that red ginger extract contains phenolic compounds, which have been shown to protect against metabolic disorders such as hypercholesterolemia. Hypercholesterolemia results from increased cholesterol levels and increased production of free radicals. Phenolic compounds reduce the risk of hypercholesterolemia by (1) increasing the activity of antioxidant enzymes, (2) decreasing the formation of free radicals, hydroxyl radicals, and superoxide anions, (3) inhibiting lipid peroxidation, and (4) regulating low-density lipoprotein (LDL) receptors .Red ginger is reported to (1) inhibit lipid peroxidation, (2) increase antioxidant enzymes, (3) regulate low-density lipoprotein (LDL) receptors, and (4) regulate 3-hydroxy-3-methylglutaryl coenzyme-A receptors (HMG-CoA), which affect cholesterol absorption in the liver ,91.Oboh et al. have reported the acetylcholinesterase (AChE) inhibitory effect of red ginger in SNP-induced mice . Red ginThe vanilloids of red ginger have a potent antioxidant effect . Yang etAedes albopictus, Aedes aegypti, and Culex quinquefasciatus. The major principal constituents in the extract were zingerone (14.92%) and benzaldehyde dimethyl thiol acetal (11.61%). Another study reported the insecticidal activity of red ginger against Spodoptera frugiperda [Mahardika et al.  reportedugiperda  via incrEscherichia coli-infected mice [E. coli strain O157 [Red ginger is usually one of the ingredients in immunomodulating supplements. A study showed that the administration of black cincau and red ginger had immunomodulatory effects in infected mice. Exposure of infected mice to red ginger and black cincau can help them to recover the small intestine mucosa structure. This study demonstrates that red ginger extract can have an immunomodulatory effect in ted mice . The comted mice . Due to ain O157 .Red ginger is one of the ingredients in Wedang uwuh . WU has antioxidant activity, can promote blood circulation, and improves immunity. WU extract administered via 27 mL/kg injections had a dose-dependent immunomodulatory potential in diabetic rats. The results showed that WU significantly inhibited the expression of pro-inflammatory cytokines and anti-inflammatory cytokines and achieved a balance between pro-inflammatory and anti-inflammatory cytokines that was not significantly different from that of normal controls. This study\u2019s results confirm that the use of WU can result in immunomodulatory activity in diabetic rats.Yamauchi et al.  reportedGrowth conditions influence the chemistry and content of active ingredients in any plant; therefore, developing analytical methods to determine the identity and quality is essential. Two anam/z. A Waters Atlantis T3 column  was used and the column temperature was maintained at 40 \u00b0C. The mobile phase was a binary eluent of (A) 5 mM (NH4)OAc solution and (B) CH3CN under the following gradient conditions: 0\u201330 min, linear gradient from 10% to 100% B; 30\u201340 min, isocratic at 100% B. The flow rate was 0.2 mL/min.The chemical fingerprint analysis was reported using HPLC-TOF-MS. The optRed ginger has gained traction, especially in Asia, where it is known for its medicinal effects: dispelling wind from the body, relieving indigestion, improving blood circulation, and relieving inflammation. The beneficial effects attributed to the constituents of red ginger have occasioned the creation of various medicinal products. In Southeast Asia, red ginger is locally known as halia bara, halia merah, or jahe merah. Currently, the red ginger products marketed in Southeast Asia include foodstuffs such as dried ginger pieces and pickled ginger, and red ginger extracts in instant beverages such as tea and coffee. Furthermore, red ginger extracts are also added to body lotions, creams, ointments, and capsules.Our research group has avidly studied ginger, its constituents, and their pharmacological properties. We prepared this review to present a concise summary of the information on red ginger gathered from the scientific literature thus far. We believe that this will be useful to researchers who are working on ginger, natural products, functional foods, and even ethnomedicine. From our perspective, based on our experience with ginger variants, the following are the main differences between red ginger and common ginger. They are: (1) they differ in color and size; (2) fresh red ginger is more pungent than fresh common ginger; (3) upon drying, red ginger turns black, while common ginger does not; (4) dried red ginger is much harder than dried common ginger; (5) the constituents are reported to be the same in both gingers; however, red ginger is reported to be more biologically active; (6) a few studies have reported that the active constituents (gingerols and shogaols) are higher in red ginger than in common ginger; (7) it is very difficult to distinguish these two variants based on the chemical composition via simple analytical techniques using HPLC and GC instruments; (8) there have been no studies characterizing the constituent that gives red ginger its color; (9) there are no studies on why red ginger is hotter than common ginger; and (10) there are no detailed studies that compare the bioactivities of red ginger and common ginger under the same experimental conditions that clearly explain why red ginger is preferred in ethnomedicine, etc.To date, conclusions on the differences between red ginger and common ginger have yet to be drawn. We strongly believe that it is still worth scientifically exploring the effects of red ginger. The research should be carried out on a standardized extract rather than individual compounds in the physiologically relevant models and molecular mechanisms. It is well established that vanilloids are unique compounds in all ginger variants. Based on our experience with ginger, we believe that red ginger\u2019s chemistry (both primary and secondary metabolites) is different from common ginger, giving rise to a difference in the hotness and biological activities. In our opinion, the plant preparations (consisting of active and inactive constituents) in ethnomedicine are equivalent to modern formulations  and excipients). It is well known that excipients in a formulation influence the bioactivity of API. Similarly, the inactive constituents in a plant extract also influence the bioactivity of the active constituents.https://go.drugbank.com/drugs, accessed on 20 November 2021), which indicates the potential for ginger to be used in modern medicine for therapeutic purposes.Red ginger extracts are scientifically validated for their beneficial effects in inflammatory diseases, metabolic diseases, cancer, neurological diseases, and cardiovascular diseases. Research in these disease areas is still a priority for many researchers, institutions, and the pharmaceutical industry. Thus, like herbal medicine, we argue that red ginger has a lot of potential to provide breakthroughs for these diseases. The ginger extract, ginger oil, and zingerone (pungent components of ginger) are included in DrugBank (This review summarizes the latest research progress on red ginger regarding its chemistry, ethnomedicinal uses, biological activities, molecular mechanism, and analytical methods. We have provided our perspectives on the value of red ginger in metabolic and neurological diseases. The vanilloids are unique to ginger, and are stable in ginger. However, upon isolation in pure form, they are not stable at room temperature. Although vanilloids are simple molecules, their synthesis is still challenging. Thus, further exploring the potential of red ginger in medicine is essential. Many herbal formulations containing red ginger are famous in various traditional systems of medicine. Many scientific studies worldwide have proven the efficacy of red ginger in a wide array of diseases\u2014metabolic, neurological, cardiovascular, infectious, and cancer. Despite red ginger being relatively safe ,95, cons"}
{"text": "Error in Institutional Review Board Statement :In the original publication, the Institutional Review Board Statement was incorrect. The authors apologize for the omission and for any inconvenience caused, and state that the scientific conclusions are unaffected. The original publication has also been updated.Corrected Institutional Review Board Statement:\u201cThe authors confirm that this study has been ethically reviewed by the Bio-Ethics Committee of the University of Turin [UOR: SI000045\u2014Classif. III/11] under protocol number 0011298 and that ethical approval was granted in January 2012.\u201d"}
{"text": "Subsequently to the comments raised by the reader, the authors themselves contacted the Editorial Office to request a retraction of the above paper on account of not being to reproduce the results shown in the Oncology Reports, and in line with the authors\u2019 own request, the Editor has decided that this paper should be retracted from the Journal. The Editor apologizes to the readership for any inconvenience caused.Owing to the fact that the contentious data in the above article had already been published elsewhere prior to its submission to"}
{"text": "The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates."}
{"text": "Furthermore, they regret any inconvenience that this mistake has caused."}
{"text": "Therefore, the affiliations for this paper should have been written as follows (changes are highlighted in bold):1*, ZHENG LI1*, GUANGMING WANG1, XIAOXUE TIAN1, JIE ZHOU1, WENLEI YU1, ZHUOYI FAN1, LIN DONG1, JINYUAN LU1, JUN XU2, WENJUN ZHANG1 and AIBIN LIANG1FANGCE WANG1Department of Hematology, Tongji Hospital, Tongji University School of Medicine, Shanghai 200092; 2Medical Center for Stem Cell Engineering and Transformation, East Hospital, Tongji University School of Medicine, Shanghai 200120, P.R. China*Contributed equallyThe authors confirm that there are no further errors in the paper, and all the authors agree to this correction. The authors and the Editor apologize for any inconvenience caused."}
{"text": "Entropy 2020, 22, 61\u201d. Firstly, there was an obvious and easily corrected mathematical error at the end of Section 6 of the paper. In the Clifford algebra under consideration, the basis bivectors M does square to the identity and hence non-zero divisors of zero, Corrections are made to my paper \u201cGill, R.D. Does Geometric Algebra Provide a Loophole to Bell\u2019s Theorem? ad hominem and ad verecundam arguments, a number of scientifically superfluous but insulting sentences have been deleted, and other disrespectful remarks have been rendered neutral by omission of derogatory adjectives. I would like to apologize to Dr. Joy Christian for unwarranted offence.Secondly, in response to a complaint about The end of Section 6 of Gill (2020)  discusseM squares to v. It satisfies One can take as basis for the eight-dimensional real vector space M squares to But the bivectors"}
{"text": "After publication of this article  and ExprThe authors stated that this overlap was due to an error in figure preparation, and that the IRF1 panels are incorrect. They provide here an updated version of PLOS ONE Editors apologize that this issue was not identified prior to publication of the Expression of Concern [The  Concern .S2 FileLevel of glycoprotein expression was determined by immunofluorescence assay for the group of IRF1 and its control (pcDNA3), and the group of sh-IRF1 and its control (pSilencer).(ZIP)Click here for additional data file."}
{"text": "Experimental & Molecular Medicine 10.1038/s12276-018-0133-y, published online 05 September 2018Retraction to: The authors have retracted this article. After publication they repeated the experiments further increasing the expression of KCNMA1 but found that this did not activate the cGMP PKG signaling pathway. The authors now believe that the mechanism by which the KCNMA1 gene inhibits the cGMP PKG signaling pathway affecting the disease is not one-to-one regulation. All authors agree to this retraction."}
{"text": "The authors apologize for The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Erratum zu:Chirurg 202110.1007/s00104-021-01364-2Der Name des Erstautors Ralf B\u00f6thig ist im urspr\u00fcnglich publizierten Beitrag nicht korrekt genannt worden. Die Autoren bitten den Fehler zu entschuldigen."}
{"text": "This abstract has been withdrawn."}
{"text": "Nature Communications 10.1038/s41467-021-26743-5, published online 18 November 2021.Correction to: The HTML version of this Article incorrectly omitted Supplementary Movie 1\u201314. Supplementary Movie 1\u201314 can be found as Supplementary Information associated with this Correction.Supplementary Movie 1Supplementary Movie 2Supplementary Movie 3Supplementary Movie 4Supplementary Movie 5Supplementary Movie 6Supplementary Movie 7Supplementary Movie 8Supplementary Movie 9Supplementary Movie 10Supplementary Movie 11Supplementary Movie 12Supplementary Movie 13Supplementary Movie 14"}
{"text": "Affordable, reliable and high-quality child and elderly care services are essential for employees to do teleworking in an efficient manner."}
{"text": "Retracted RetractedRetractedRetractedRetractedRetracted"}
{"text": "Effective treatment of glioma requires a nanocarrier that can cross the blood\u2013brain barrier (BBB) to target the tumor lesion. In the current study, elemene (ELE) and cabazitaxel (CTX) liposomes were prepared by conjugating liposomes with transferrin (Tf) and embedding the cell membrane proteins of RG2 glioma cells into liposomes , which exhibited effective BBB infiltration to target glioma.The findings showed that Tf-ELE/CTX@BLIP was highly stable. The liposomes exhibited highly significant homologous targeting and immune evasion in vitro and a 5.83-fold intake rate compared with classical liposome (ELE/CTX@LIP). Bioluminescence imaging showed increased drug accumulation in the brain and increased tumor penetration of Tf-ELE/CTX@BLIP in orthotopic glioma model nude mice. Findings from in vivo studies indicated that the antitumor effect of the Tf-ELE/CTX@BLIP led to increased survival time and decreased tumor volume in mice. The average tumor fluorescence intensity after intravenous administration of Tf-ELE/CTX@BLIP was 65.2, 12.5, 22.1, 6.6, 2.6, 1.5 times less compared with that of the control, CTX solution, ELE solution, ELE/CTX@LIP, ELE/CTX@BLIP, Tf-ELE/CTX@LIP groups, respectively. Histopathological analysis showed that Tf-ELE/CTX@BLIP were less toxic compared with administration of the CTX solution.These findings indicate that the active-targeting biomimetic liposome, Tf-ELE/CTX@BLIP, is a promising nanoplatform for delivery of drugs to gliomas.The online version contains supplementary material available at 10.1186/s12951-021-01048-3. P-gp) occurs on the BBB, which further increases clearance of chemotherapy drugs \u2009=\u200920\u00a0\u03bcg/mL) and incubated for 2\u00a0h. In addition, RG2 cells were seeded into a 6-well plate (3\u2009\u00d7\u2009105 cells/well) and incubated with ELE/CTX@LIP, ELE/CTX@BLIP, Tf-ELE/CTX@LIP and Tf-ELE/CTX@BLIP (Rho B\u2009=\u200920\u00a0\u03bcg/mL) for 2\u00a0h. The medium was removed and cells were fixed with 4% paraformaldehyde, stained with DAPI and washed thrice with PBS. The cellular uptake was determined by confocal laser scanning microscope imaging  and flow cytometry [Tf-ELE/CTX@BLIP was incubated with SPC-A-1 cells, A549 cells, MDA-MB-231 cells, LM-3 cells, U251 cells, C6 cells, and RG2 cells, separately. Cells were inoculated into 6-well plates  for 2\u00a0h. Effect on immune evasion was then determined by CLSM and flow cytometry .Cytotoxicity effects of ELE/CTX@LIP, ELE/CTX@BLIP, Tf-ELE/CTX@LIP and Tf-ELE/CTX@BLIP on RG2 cells were determined using a CCK-8 kit. RG2 cells (3000\u00a0cells/well) were inoculated in 96-well plates and incubated for 24\u00a0h. After incubation, cells were exposed to ELE/CTX@LIP, ELE/CTX@BLIP, Tf-ELE/CTX@LIP and Tf-ELE/CTX@BLIP (CTX concentrations ranging from 0.4 to 200\u00a0ng/mL) for 48\u00a0h. Non-treated cells were used as negative controls. Medium was evaluated as the blank control. Cytotoxicity was quantitatively determined by measuring the absorbance at 450\u00a0nm using a Spark multi-functional microporous plate testing platform .Furthermore, apoptotic cells were determined by FACS analysis . RG2 cells were incubated with ELE/CTX@LIP, ELE/CTX@BLIP, Tf-ELE/CTX@LIP and Tf-ELE/CTX@BLIP and 50\u00a0ng/mL CTX for 48\u00a0h then treated with the apoptosis detection kit  for 10\u00a0min. Percentage of apoptotic cells was determined using a FACS Calibur System. Non-treated cells were used as the negative control .5\u00a0cells/well) and incubated for 24\u00a0h. Rhodamine 123  was preconditioned with ELE/CTX@LIP, ELE/CTX@BLIP, Tf-ELE/CTX@LIP, Tf-ELE/CTX@BLIP (50\u00a0ng/mL) and verapamil (0.625\u00a0\u03bcg/mL) separately for 30\u00a0min then it was exposed to bEnd.3 for 2\u00a0h. The medium was removed and bEnd.3 cells were fixed with 4% paraformaldehyde for 30\u00a0min and washed thrice with PBS. Cells were then analyzed using fluorescence microscope and flow cytometry. Relative expression level of P-gp in bEnd.3 cells was determined by WB assay. bEnd3 cells in 6-well plates were conditioned with medium and verapamil, ELE/CTX@LIP, ELE/CTX@BLIP, Tf-ELE/CTX@LIP, Tf-ELE/CTX@BLIP were added [bEnd.3 cells were cultured as described in the \u201cre added .Female nude mice  were obtained from Shanghai Slack Laboratory Animal Co. LTD. Mice were allowed to acclimatize at room temperature for 7\u00a0days prior to the performing animal studies. Animals were housed under the animal care facility and allowed free access to food/water. All animal experiments were approved by the animal ethics committee of Hangzhou Normal University .7 glioma-luc cells in medium were injected slowly into the brain right striatum of nude mice . The needle was maintained at the injection point for 1\u00a0min after injection and then pulled out slowly. Alcohol cotton swabs were used to disinfect the skin, the skin was sewn with a needle and thread. The mice were then placed back to the cage to wake up naturally. Rate of growth of intracranial tumor was monitored by magnetic resonance imaging (MRI) and fluorescence imaging.Glioma-luc cells were injected into the right striatum of nude mice to develop a orthotopic glioma-bearing model. Nude mice were anesthetized through administration of 10% chloral hydrate and the head was immobilized on a stoelting . Approximately 2.5\u2009\u00d7\u200910Cypate\u2009=\u20090.1\u00a0mg/mL) were injected into normal mice and glioma-bearing mice through the tail vein. Bioluminescence imaging was performed at fixed times  using a small animals in vivo 3D bioluminescence imaging system .The nude mice were then sacrificed, and brains, liver, heart, spleen, lung, and kidney were collected for quantitative biodistribution analysis and ex vivo bioluminescence imaging [Orthotopic glioma-bearing model was established by injecting RG2 cells into the brain striatum as described above. Cypate, Cypate@LIP, Cypate@BLIP, Tf-Cypate@LIP and Tf-Cypate@BLIP (CP-gp.Orthotopic glioma-bearing model nude mice were randomly assigned into seven groups (6 mice/group) as follows: (1) control ; (2) CTX solution; (3) ELE solution (25\u00a0mg/kg ELE); (4) ELE/CTX@LIP; (5) ELE/CTX@BLIP; (6) Tf-ELE/CTX@LIP; (7) Tf-ELE/CTX@BLIP, to explore the anti-tumor effect in vivo. Treatments were administered by intravenous injection through the tail at day 1, 3, 5, 7, 9 and 11. Group 2, 4, 5, 6, 7 was administered with 2.5\u00a0mg/kg (CTX) on the first time and 0.625\u00a0mg/kg for the subsequent 5 injections. Bioluminescence imaging was performed at day 1, 5, 10, and 15 to explore tumor growth. Body weight and survival time were recorded every 3\u00a0days. Nude mice were euthanized 2\u00a0h post-treatment and their brains were collected for H&E staining, TUNEL immunofluorescence staining and detection of glioma Glioma-bearing nude mice were assigned into seven groups and were administered with (1) control ; (2) CTX solution; (3) ELE solution; (4) ELE/CTX@LIP; (5) ELE/CTX@BLIP; (6) Tf-ELE/CTX@LIP; (7) Tf-ELE/CTX@BLIP, 6 times and every other day. Whole blood samples were collected from retro-orbital sinus of glioma-bearing nude mice 2\u00a0h post-treatment. A portion of the complete blood samples was used for complete blood count analysis. The supernatant (serum) of the portion of blood obtained after centrifugation  was used for determination of biochemical indexes of liver and kidney, including total bilirubin, blood urea nitrogen, uric acid, alanine transaminase, creatinine and aspartate transaminase level. Liver, heart, spleen, lung and kidney sections were stained with H&E to evaluate effects of free ELE, CTX solution and liposomes toxicity .t test for comparison between two groups and ANOVA for comparison among multiple groups. Statistical difference was defined as significant for *p\u2009<\u20090.05 and highly significant for **p\u2009<\u20090.01.GraphPad Prism 8.0.2.263 software  was used for statistical analysis. Data were expressed as mean\u2009\u00b1\u2009SD. Experimental data were analyzed using two-tailed Student Additional file 1: Table S1. Encapsulation efficiency stability of the drug in 4 liposomes at 3 months\u00a0(n = 3). Fig. S1. Diameter and \u03b6-potential of Tf-ELE/CTX@BLIP, Tf-ELE/CTX@LIP, ELE/CTX@BLIP and ELE/CTX@LIP. Fig. S2. 7-days stability of TF-ELE/CTX@BLIP diameter in different medium. Fig. S3. Flow cytometry analysis of RG2 glioma cells after incubation with Tf-ELE/CTX@BLIP, Tf-ELE/CTX@LIP, ELE/CTX@BLIP and ELE/CTX@LIP for 2 h. Rho B = 20 \u03bcg/mL. Fig. S4. CLSM images of RG2, U251 and C6 glioma cells treated with Tf-ELE/CTX@BLIP for 2 h. Scale bar = 50 \u03bcm. Fig. S5. Flow cytometry analysis of RAW264.7 cells treated with Tf-ELE/CTX@BLIP, Tf-ELE/CTX@LIP, ELE/CTX@BLIP and ELE/CTX@LIP for 2 h. Rho B = 20 \u03bcg/mL. Fig. S6. WB analysis of P-gp in bEnd.3 cells. Relative protein expression was calculated. Cells preconditioned with (1) control; (2) verapamil; (3) ELE/CTX@LIP; (4) ELE/CTX@BLIP; (5) Tf-ELE/CTX@LIP; (6) Tf-ELE/CTX@BLIP. . Fig. S7. Corresponding quantitative fluorescent analysis of brain, liver, heart, spleen, lung and kidney at 48 h post-injection in glioma-beard mice. *p < 0.05. Fig. S8. In vivo fluorescence imaging of Tf-Cypate@BLIP, Tf-Cypate@LIP, Cypate@BLIP and Cypate@LIP in normal mice. Cypate = 0.5 mg/kg. Fig. S9. Averaged fluorescent intensity of saline, free CTX, free ELE, ELE/CTX@LIP, ELE/CTX@BLIP, Tf-ELE/CTX@LIP and Tf-ELE/CTX@BLIP in nude mice bearing orthotopic glioma brain within 15 days of treatments. Fig. S10. H&E staining of brain sections of orthotopic glioma-bearing mice in different formulation groups. Fig. S11. Biochemical parameter analysis after treated with saline, free CTX, free ELE, ELE/CTX@LIP, ELE/CTX@BLIP, Tf-ELE/CTX@LIP and Tf-ELE/CTX@BLIP. (A) BLI-T: total bilirubin, (B) BUN: blood urea nitrogen, (C) URIC: uric acid, (D) ALT: alanine transaminase, (E) CRE: creatinine, (F) AST: aspartate transaminase."}
{"text": "TP53 aberrations exert a more detrimental prognostic impact, compared to biallelic alterations.\u201d This is incorrect. It should read: \u201cMonoallelic TP53 alterations exert a less detrimental prognostic impact, compared to biallelic alterations.\u201dThere was an error in the original publication. Page 3. \u201cMonoallelic TP53 mutations [2].\u201d Reference [2] was erroneously cited. The correct reference here should be reference [1]. This sentence should read: \u201cIn fact, among our recently reported cohort of 20 spontaneously regressing CLL cases, three harbored TP53 mutations [1].\u201dThere was an error in the original publication. Page 13. \u201cIn fact, among our recently reported cohort of 20 spontaneously regressing CLL cases, three harbored There was an error in the original publication. Page 14. \u201cin combination with existing immunomodulatory agents such as the PD-1/PD-L1 inhibitors lenalidomide and ibrutinib\u201d This sentence should read in \u201cin combination with existing immunomodulatory agents such as PD-1/PD-L1 inhibitors, lenalidomide and ibrutinib.\u201dIn the original publication, there was a mistake in Table 1: \u201cD\u00f6hner\u201d was misspelt as \u201cDoner\u201d. The corrected The authors wish to make the following corrections to their paper :There waThe authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. The original publication has also been updated."}
{"text": "In"}
{"text": "The authors regret that the image of OS-RC-2 invasion group was wrongly attached due to their carelessness in assembling figures Fig.D 1. The The correction made in this erratum does not affect the original conclusions. The authors apologize for any inconvenience or misunderstanding that this error may have caused."}
{"text": "Bioinformatics (2020) doi: 10.1093/bioinformatics/btaa758\u201cThe title of this paper was originally, erroneously displayed as \u201cDecombinator V4: an improved AIRR compliant-software package for T-cell receptor sequence annotation?\u201d. This should have appeared as \u201cDecombinator V4: an improved AIRR-C compliant software package for T-cell receptor sequence annotation. This has now been corrected online\u201d."}
{"text": "We acknowledge the points raised by Hodac and Wittekind  and woulWe thank the authors for the opportunity to discuss our findings in more detail. A more in-depth comparison between our estimates and the one provided by  is limit"}
{"text": "After publication of the original article, the authors noted that thefollowing error had occurred:Molecular profilingidentified a subset of SOX2-regulated miRNAs in glioma stemcells\u201d. In the passage that reads:The wrong publication was referenced in the analysis performed to identifySox2-regulated miRNAs in the section entitled \u201cTo provide robustness to this miRNA profile, we cross-referenced ourmiRNA array results to a set of miRNAs identified by Lopez-Bertoni andcolleagues to be regulated by exogenous expression of SOX2 in GSCs. Lopez et. al. identified 21 down-regulated and 56up-regulated miRNAs in GSCs expressing exogenous SOX2."}
{"text": "The beginning of the Supplemental text should have appeared as below. The error only exists in PDFs downloaded before March 9, 2021.f(t) that describes the kinetics of a Ca2+ transient:Let\u2019s have a function"}
{"text": "The authors have retracted this article because following verification, the results of the statistical analysis of the data presented in Fig.\u00a04D and Fig.\u00a06D were identified to be incorrect; specifically, the TUNEL assay results indicated that microRNA-144 could not reverse the effects of HCG11 on apoptosis, which affected the overall conclusions of the study.All authors agree to this retraction."}
{"text": "In"}
{"text": "None of the authors should have been attributed equal contribution to this work."}
{"text": "The authors regret that the affiliations for Professor F. Puglisi are incorrect. They should be:CRO Aviano National Cancer Institute IRCCS, Aviano, Italy and Department of Medicine (DAME), University of Udine, Udine, ItalyThe authors would like to apologise for any inconvenience caused."}
{"text": "The Competing Interests statement published incorrectly. The publisher apologizes for the error. The correct statement is as follows: The authors have read the journal\u2019s policy and the authors of this manuscript have the following competing interests: JT discloses a consulting relationship with Genetika, and JKW discloses paid employment with the Center for Translational Bioethics and Health Care Policy at Geisinger during the conduct of this study but no active competing interests at the time of publication. The authors have declared that no other competing interests exist and that the authors have no financial interests  related to this study to declare. This does not alter our adherence to PLOS ONE policies on sharing data and materials."}
{"text": "We apologize for the errors and for any inconvenience thatthis may have caused the readers of"}
{"text": "There are errors in the Funding statement. The correct Funding statement is as follows: The authors received no specific funding for this work."}
{"text": "After having been in contact with the authors, they agreed with the decision to retract the paper. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors attention by a concerned reader that certain of the western blotting data shown in Figs. 4C, 5B and 6D were strikingly similar to data appearing in different form in other articles by different authors. Owing to the fact that the contentious data in the above article were already under consideration for publication, or had already been published, elsewhere prior to its submission to"}
{"text": "The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates."}
{"text": "Investigation of a pertussis outbreak and comparison of two acellular booster pertussis vaccines in a junior school in South East England, 2019\u2019 by Tessier et al., published on 25 March 2021, Repevax was mistakenly stated as having ten times more pertussis toxid than Infanrix. The text was corrected on 13 January 2022 on request of the authors. In the article \u2018"}
{"text": "This Retraction follows an Expression of Concern relating to this article previously published by Portland Press.Bioscience Reports at the request of the Editor-in-Chief and the Editorial Board following receipt of a notification from a reader, alerting the Editorial Board to a duplicated image in Figure 4D.This article is being retracted from The authors were contacted regarding the concerns raised and provided a replacement images for Figures 2D, 3F and 4D, however given that the replacement images for Figure 2D also contained a new duplicated image, the Editorial Board stands by the decision to retract. The authors were contacted in regards to the retraction but did not respond."}
{"text": "The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates."}
{"text": "The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates."}
{"text": "There is an error in"}
{"text": "While Europe\u2019s response to the pandemic has been laudable, there remains more to be done in order to prevent economic scarring and ensure a robust recovery."}
{"text": "PLOS Genetics Editors that results from experiments reported in Fig 5M and 5N were not reproducible in follow-up experiments, raising questions about the validity of the main conclusions.Following publication of this article , the autIn Fig 5M and 5N of this article , the autGiven the results noted above, the authors consider the conclusions, and in particular the results reported in Fig 5M and 5N, invalid. Therefore, the authors are retracting this publication.PLOS Genetics for the inconvenience.The authors apologize to the readers and editors of All authors agreed with the retraction."}
{"text": "In the article titled \u201cChaperone-Mediated Autophagy Markers LAMP2A and HSC70 Are Independent Adverse Prognostic Markers in Primary Resected Squamous Cell Carcinomas of the Lung\u201d , the aut\u201cLAMP2A HSC70 \u201dto\u201cLAMP2A HSC70 \u201d"}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office never received any reply. The Editor regrets any inconvenience that has been caused to the readership of the Journal.After having conducted an independent investigation in the Editorial Office, the Editor of"}
{"text": "In"}
{"text": "Erratum for Volume 12, no. 3, e00560-21, 2021, In"}
{"text": "Fig. S3D and E).\u201d Following the publication of the above article, the authors have realized that, on p. 8, some of the supplementary data were cited incorrectly in the main text. In the right-hand column, second paragraph, the sentence beginning on line 5 should have read as follows (changed text is highlighted in bold): \u201cMeanwhile, the expression of miR-513b-5p in tumor tissues was decreased and the expression of PRPF39 was increased in tumor tissues with knockout of circ-G004213 (The authors regret their oversight in failing to correct the inaccurate citation of the data in the paper, are grateful to the Editor for allowing them the opportunity to publish this Corrigendum, and apologize to the readership for any inconvenience caused."}
{"text": "The authors would like to make an addendum to their published paper .The animal experimentation methodology was reviewed and approved by the Animal Welfare Committee of E\u00f6tv\u00f6s Lor\u00e1nd University (reference number TTK/6859/1 (2021), certificate number ELTE-AWC-011/2021), and additionally by a higher governmental office .Furthermore, the authors retrospectively obtained the approval for the human ethical aspects of the informed consent form and the participant prospectus for the dog owners who participated with their dogs in the experiments .Animals.The authors submitted all the above mentioned documents, along with a copy of the owner consent form and participant prospectus, to In the originally published version of this article, ethical information was omitted, so the authors wish to add the following information regarding the ethical approval process of the experimental protocols:The change does not affect the scientific results.The rest of the manuscript does not need to be changed."}
{"text": "Bioinformatics (2021), Volume 37(Suppl1), i468\u2013i476, doi:10.1093/bioinformatics/btab331Precision and Recall  were erroneously provided as: In the original published version, the formulae for\u00a0The correct formulae that were consistently used throughout the experiments are as follows:The error is thus only in mis-typing the formulae themselves; not in the actual calculations of the precision and the recall used throughout the paper.As such, the other parts of the manuscript \u2013 specifically the experimental results reported, all stand as they appear in the original publication, and are not impacted by this correction."}
{"text": "In our paper"}
{"text": "In fact, in the original publication, the spectra are plotted as functions of angular frequency.The authors wish to make the following corrections to this paper: . In SectBecause of the above mentioned"}
{"text": "Soc. Rev., 2021, 50, 7820\u20137880, DOI: 10.1039/D0CS00729C.Correction for \u2018The multifaceted nature of antimicrobial peptides: current synthetic chemistry approaches and future directions\u2019 by Bee Ha Gan  The authors regret that the following funding information was omitted from the original article: \u201cWe gratefully acknowledge the financial support from the Swiss National Science Foundation (P2BEP2-191784) to B. H. G.\u201dThe Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "In"}
{"text": "The COVID-19 crisis has revealed the deep technological and production dependencies of the EU on third countries in sectors deemed as particularly strategic and has thus fuelled the debate on (the lack of) European technological sovereignty in critical fields. This article argues that in the light of a renewed interest in relaunching a European industrial policy, technological sovereignty considerations must be fully incorporated into policy objectives and instruments."}
{"text": "After having been in contact with the authors, they agreed with the decision to retract the paper. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors\u2019 attention by a concerned reader that the western blotting assay data shown in Fig. 2B were strikingly similar to data appearing in different form in other articles by different authors. Owing to the fact that the contentious data in the above article had already been published elsewhere, or were already under consideration for publication, prior to its submission to"}
{"text": "Humanities and Social Sciences Communications 10.1057/s41599-021-00805-x, published online 27 May 2021.Correction to: The affiliation of one of the authors was wrongly stated as:Kumaran Rajandran, School of Humanities, Universiti Sains, Sains, MalaysiaThis has now been corrected to:Kumaran Rajandran, School of Humanities, Universiti Sains Malaysia, George Town, MalaysiaThis has been corrected in all versions of the paper."}
{"text": "Correction of conflict of interest statementOriginal statement: The authors declare that they have no conflict of interest.Corrected version:Conflict of interestThe authors, except dr. Philippe Lambin, declare that they have no conflict of interest.Dr. Lambin reports, within and outside the submitted work, grants/sponsored research agreements from Varian medical, Oncoradiomics, ptTheragnostic, Health Innovation Ventures and DualTpharma. He received an advisor/presenter fee and/or reimbursement of travel costs/external grant writing fee and/or in kind manpower contribution from Oncoradiomics, BHV, Merck and Convert pharmaceuticals. Dr Lambin has shares in the company Oncoradiomics SA and Convert pharmaceuticals SA and is co-inventor of two issued patents with royalties on radiomics  licensed to Oncoradiomics and one issue patent on mtDNA (PCT/EP2014/059089) licensed to ptTheragnostic/DNAmito, three non-patentable invention (softwares) licensed to ptTheragnostic/DNAmito, Oncoradi\u00adomics and Health Innovation Ventures."}
{"text": "The following statement should be added to the Acknowledgments section of this paper: \u201cCRediT roles for this study are as follows: Mohammed Mufrrih: Investigation; Biyao Chen: Formal analysis, Investigation; Shiu-Wan Chan: Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing - original draft, Writing - review & editing.\u201dVolume 6, no. 3, e00361-21, 2021,"}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office never received any reply. The Editor regrets any inconvenience that has been caused to the readership of the Journal.After having conducted an independent investigation in the Editorial Office, the Editor of"}
{"text": "The journal retracts the article, Effects of a Single Dose of Ivermectin on Viral and Clinical Outcomes in Asymptomatic SARS-CoV-2 Infected Subjects: A Pilot Clinical Trial in Lebanon , cited aFollowing publication, the authors contacted the editorial office regarding an error between files used for the statistical analysis.Adhering to our complaints procedure, an investigation was conducted that confirmed the error reported by the authors.This retraction was approved by the Editor in Chief of the journal.The authors agreed to this retraction."}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive any reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors\u2019 attention by a concerned reader that the Transwell cell migration assay data shown in Fig. 2C were strikingly similar to data appearing in different form in other articles by different authors. Owing to the fact that the contentious data in the above article had already been published elsewhere, or were already under consideration for publication, prior to its submission to"}
{"text": "The authors wish to make the following corrections to this paper :Change in Author Names (Add a new one)In the original version of our article , the stuThe corrected author list, affiliation list, authors contribution, and acknowledgements are provided below:Mart\u00ednezGuillermo1MerineroManuel1P\u00e9rez-ArandaMar\u00eda1P\u00e9rez-SorianoEva Mar\u00eda2OrtizTamara3VillamorEduardo4BeginesBel\u00e9n1*AlcudiaAna1*1Department of Organic and Medicinal Chemistry, Faculty of Pharmacy, University of Seville. C/Profesor Garc\u00eda Gonz\u00e1lez, 2, 41012 Seville, Spain; mtnezmun@gmail.com (G.M.); lolo191995@gmail.com (M.M.); mariapar89@gmail.com (M.P.-A.)2Department of Materials Science and Engineering and Transport, Escuela Polit\u00e9cnica Superior, University of Seville, 41011 Seville, Spain; evamps@us.es3Department of Normal and Pathological Cytology and Histology, Faculty of Medicine, University of Seville, 41009 Seville, Spain; tortiz@us.es4Faculty of Pharmacy, University of Seville. C/Profesor Garc\u00eda Gonz\u00e1lez, 2, 41012 Seville, Spain; eduardovillamors@gmail.com*Correspondence: bbegines@us.es (B.B.); aalcudia@us.es (A.A.)Authors\u00a0Contributions:Conceptualization and methodology, B.B. and A.A.; investigation, G.M., M.M., M.P.-A., and E.V.; writing\u2014original draft preparation, G.M., M.M., M.P.-A., E.M.P.-S., T.O., and E.V.; writing\u2014review and editing, T.O. and E.M.P.-S.; supervision, B.B., A.A.; funding acquisition, A.A. All authors have read and agreed to the published version of the manuscript.Acknowledgments:\u00a0University of Seville Library for providing access to scientific and technical information resources. Some figures have been designed using resources from Freepik.com.The authors would like to apologize for any inconvenience caused to the readers by these changes."}
{"text": "Furthermore, the flow cytometric plots shown in Fig. 2B in the above paper appeared to be remarkably similar to data presented in a paper published in Oncology Reports has determined that the above paper should be retracted from the Journal on account of a lack of confidence concerning the originality and the authenticity of the data. The authors were asked for an explanation to account for these concerns, but the Editorial Office never received any reply. The Editor regrets any inconvenience that has been caused to the readership of the Journal.After having conducted an independent investigation in the Editorial Office, the Editor of"}
{"text": "The authors apologize for the original versions of our paper unfortunately contained some incorrect representative images. We used the wrong representative images during figure assembly. The IHC images of 7dCon-Runx2, 10dCon-CD146/COL1A1 and 10dT-Del-Runx2 in Figure The authors confirm that the corrections made in this erratum do not affect the original conclusions. The authors apologize for any consequences that these errors may have caused."}
{"text": "The authors regret that the scale bars for the SEM image in Fig. 3a and c were mislabelled. The correct scale bar should be 100 \u03bcm, and the corresponding SEM images are shown below.Fig. 3a SEM surface morphology for single layer DLC film.Fig. 3c SEM surface morphology for multilayer DLC film.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "We thank Ravnskov  for his"}
{"text": "There is an error in There is also an error in In Tables"}
{"text": "In the ITS2 fragment sequence analysis subsection of the Results, there is an error in the fifth sentence of the first paragraph. The correct sentence is: For example, a sample from western Sumba (SM1-108) possessed a G>T transversion at nt 538 but lacked a base transition at nt 479 .The images for Figs"}
{"text": "VOLUME 285 (2010) PAGES 26532\u201326544C panel 3is duplicated in Fig.\u00a010A, b iii. Fig.10A, a iii is duplicated as Fig.\u00a01 inMicrobiology (2009), 155: 780\u2013790.Fig.\u00a05C panel 6 is duplicated asFig.\u00a01A, b ii right, Fig.\u00a010A, a iii isduplicated as Fig.\u00a01A, a ii right, andFig.\u00a010A, c is duplicated in Fig.\u00a01A, din Plant Signaling & Behavior (2011) 6(5): 723\u2013725,respectively representing different experimental conditions. Plant Signaling& Behavior as well as Microbiology havereplaced and corrected the figures which were overlapping with theJBC figures as mentioned above. Both PlantSignaling & Behavior and Microbiology havepublished a corrigendum related to the respective figures.This article has been withdrawn by the authors except Ajay Kumar Saxenaand Deepak Kumar Deep who could not be contacted. Fig.\u00a05"}
{"text": "The authors regret that incorrect versions of The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "BJPsych Open (2022). Cambridge University Press 8(1), E14. DOI: Following publication in December 2021, discrepancies between Table 1 and the Abstract, Results and Discussion sections were discovered and the authors notified. Upon detailed investigation, further statistical and methodological problems were found and the Editors concluded that a corrigendum would not be sufficient to resolve these issues.The authors of the article agree with the decision."}
{"text": "Retraction Note to: BMC Pediatr 21, 299 (2021)https://doi.org/10.1186/s12887-021-02775-0The Editor has retracted this article because of concerns with the data presented and ethics approval for this study. After publication, the authors became aware of fundamental errors in the data presented in Tables\u00a02 and 3 that undermined the conclusions drawn in this study and contacted the journal to request a retraction. Additional concerns have been raised about the Ethics Approvals for the study since the protocol was updated, but the authors were unable to provide evidence that these changes were approved by all relevant Institutional Review Boards.Authors Ting Yang, Xi Lai, Li Chen, Jie Chen, Ming Xue and Tingyu Li agree to this retraction. Authors Jing Wen, Jiang Zhu, Min Guo and Ting Tang have not responded to any correspondence from the editor or publisher about this retraction."}
{"text": "After having been in contact with the authors, they agreed with the decision to retract the paper. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors attention by a concerned reader that certain of the western blotting data shown in Figs. 5D and 6 bore unexpected similarities to data appearing in different form in other articles by different authors. Owing to the fact that the contentious data in the above article had already been published elsewhere, or were already under consideration for publication, prior to its submission to"}
{"text": "Sci., 2021, 12, 13101\u201313119, DOI: 10.1039/D1SC04181A.Correction for \u2018HCOOH disproportionation to MeOH promoted by molybdenum PNP complexes\u2019 by Elisabetta Alberico  The authors regret that in Please note that complex 8 is also shown in Scheme 4 in the proposed mechanism for HCOOH decarbonylation (green part), and in i)-hydride species {Mo(H)(CO)2(CH3CN)[CH3N(CH2CH2P(CH(CH3)2)2)2]}. The correct formula, in agreement with the X-ray structure, is as follows and is shown above in 2(CH3CN)[CH3N(CH2CH2P(CH(CH3)2)2)2]}.Furthermore, a mistake was made in the caption of Fig. 6, showing the solid-state structure of complex 9: the latter has been incorrectly described as a Mo(The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Scientific Reports 10.1038/s41598-020-68117-9, published online 07 July 2020Correction to: The original version of this Article contained an error in the Acknowledgments section.\u201cThis paper is supported by the SILICOFCM project that has received funding from the European Union\u2019s Horizon 2020 research and innovation programme under grant agreement No 777204. This research was also funded by Ministry of Education and Science of Serbia, grants OI 174028, III 41007, III 45019 and PROMIS, Science Fund of the Republic of Serbia. The authors acknowledge support from the City of Kragujevac, Serbia.\u201dnow reads:\u201cThis paper is supported by the SILICOFCM project that has received funding from the European Union\u2019s Horizon 2020 research and innovation programme under grant agreement No 777204. This research was also funded by Ministry of Education and Science of Serbia, grants OI 174028, III 41007, III 45019. The authors acknowledge support from the City of Kragujevac, Serbia.\u201dThe original Article has been corrected."}
{"text": "The authors also apologize for any inconvenience caused, and agree to address any additional questions regarding their results. All raw data are available from the authors upon request.The corrected versions of"}
{"text": "Cardiovasc Res., cvab077, https://doi.org/10.1093/cvr/cvab077The authors have requested that Ralph Kn\u00f6ll be removed from the acknowledgments section of the paper and be added as a co-author.This change does not affect the overall scientific message of the paper."}
{"text": "With the help of Wen-Jing Li, the authors realized there was a mistake of surface temperature in the paper above. The surface temperature in the paper refers to the temperature recorded in images which was detected by the temperature receptors of the field infrared camera, instead of the real surface temperature. As there was no shelter to the field infrared camera in alpine meadow grasslands, the temperature of the camera increased rapidly under the sunshine. Thus the conclusion of the preferable temperature for pikas may be around 31~35\u00b0C was not right, neither the temperature in Figure 6. As there was no equipment to measure the surface temperature in the observation, it is hard to restore the original surface temperature. The data in Figure 6 can be used to compare the behavior characteristics of plateau pikas at different relative temperature.The authors would like to declare that the temperature in the paper refers to the temperature recorded in images which was detected by the temperature receptors of the field infrared camera, instead of the real surface temperature. The historic high air temperature in Dari County was 23.2\u00b0C . The temperature of the camera could increase rapidly under the sunshine, so the temperature in the paper can only be taken as a reference of the relative temperature.The authors would like to give an extra special thanks to Wen-Jing Li, who provides the professional advice and help.\u00a0 Thanks to the letter by The authors would like to declare that the temperature in the paper refers to the temperature recorded in images detected by the field infrared camera\u2019s temperature receptors, and does not reflect the actual surface temperature. The historic high air temperature in Dari County was 23.2\u00b0C , so the The authors would like to acknowledge Dr. Wen-Jing Li for pointing out this discrepancy in surface temperatures."}
{"text": "Addendum to:Cancer Gene Therapy10.1038/cgt.2016.51After careful review and discussions with the authors, the Editor-in-Chiefis issuing an editorial expression of concern to alert readers that the cell lines usedin this study  may have"}
{"text": "Staphylococcus aureus by silver ions\u2019 by Xiangwen Liao et al., RSC Adv., 2020, 10, 33221\u201333226. DOI: 10.1039/D0RA06357F.Retraction of \u2018Functional disruption of staphylococcal accessory regulator A from  RSC Advances article as there is an error in the data and the conclusions of the paper are not supported.We, the named authors, hereby wholly retract this +via its conserved cysteine residues.Fig. 3B does not show the titration data of SarA, it is the titration data of a different protein, and therefore we cannot unequivocally conclude that SarA binds AgThe corresponding authors regret this oversight and apologise for any inconvenience to readers.Signed: Xiangwen Liao, Guijuan Jiang, Jing Wang and Jintao Wangth February 2021Date: 17RSC AdvancesRetraction endorsed by Laura Fisher, Executive Editor,"}
{"text": "After having been in contact with the authors, they agreed with the decision to retract the paper. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors attention by a concerned reader that certain of the western blotting data shown in Figs. 3A and 4A, and tumor images in Fig. 5A, bore unexpected similarities to data appearing in different form in other articles by different authors. Owing to the fact that some of the contentious data in the above article had already been published elsewhere, or were already under consideration for publication, prior to its submission to"}
{"text": "Following publication of the original article , the autThe authors alsofound that the cells in the left three columns  were inconsistent with those in the right three columns. In order to facilitate the readers\u2019 understanding of that part of the content and avoid any possible confusion, we hereby provide the cells consistent with the right three columns as a supplement. The supplementary pictures are shown below in Fig.\u00a03 (the last row). The original full field view of the last row of Fig.\u00a03 is also provided in supplementary information Fig S2.In summary, we provide a correction of Figure 2f and a supplementary image for the last row of Fig.\u00a03 as follows:1. The correction of Fig.\u00a0Supplementary information Fig S1:2. The supplementary image for Fig.\u00a03 (the last row):Supplementary information Fig S2:The authors apologize for these errors and any inconvenience to the reader."}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive any reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors' attention by a concerned reader that certain of the Transwell cell migration assay data shown in Fig. 5A were strikingly similar to data appearing in different form in other articles by different authors. Owing to the fact that the contentious data in the above article had already been published elsewhere, or were already under consideration for publication, prior to its submission to"}
{"text": "The authors wish to make the following corrections to the paper : During 1Thi Tuong Vy Phan 1\u00a0phanttuongvy4@duytan.edu.vnCenter for Advanced Chemistry, Institute of Research and Development, Duy Tan University, 03 Quang Trung, Hai Chau, Danang 550000, Vietnam; We apologize for this unintentional mistake, which, however, does not affect the results of this manuscript and the conclusions drawn from them."}
{"text": "This Retraction follows an Expression of Concern relating to this article previously published by Portland Press.Bioscience Reports at the request of the Editor-in-Chief and the Editorial Board following receipt of a notification from a reader, alerting the Editorial Board to unusual repeated background features in the Western blots.This article is being retracted from The authors have been contacted in regard to the retraction and were asked to provide the raw images for these Western blots. However as the images provided during the investigation differed from those in the published paper and appear to show signs of editing, the Editorial Board stands by the decision to retract. The authors were asked to agree to the retraction but did not respond to the Editorial Office."}
{"text": "VOLUME 284 (2009) PAGES 16183\u201316190B and 5C, a portion ofthe actin immunoblots were reused in the SMMC7721 panels. InFig.\u00a06B, si-p53 panel, the p53 immunoblot bands for ICNand parental lanes are duplicated. Also in Fig.\u00a06B, si-p53panel, the DR5 immunoblot bands for mock and parental lanes are duplicated. InFig.\u00a0S1, the Notch 2 and Notch 3 panels are duplicated. The authors state that theydisagree with the Journal\u2019s findings. This study was conducted nearly 15\u00a0years ago.The age of the work and the lack of availability of data storage makes it difficultfor the authors to retrieve the requested raw data. The authors\u2019 offer to replacethe images in question with those from other experiments under the same conditionswas declined by the Journal. The authors state that the above issues do not affectthe interpretation of the data nor conclusions of this work. The authors state thatthe conclusions of this article have been confirmed by other independent studies.The authors have indicated that they plan to resubmit their findings elsewhere forpublication.This article has been withdrawn by the authors. The Journal statesthat in Figs.\u00a05"}
{"text": "The authors regret that the original version of our paper"}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a satisfactory reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors\u2019 attention by a concerned reader that the scratch-wound assay data shown in Fig. 2C were strikingly similar to data appearing in different form in other articles by different authors. Owing to the fact that the contentious data in the above article had already been published elsewhere, or were already under consideration for publication, prior to its submission to"}
{"text": "The authors would like to make corrections to a recently published paper . The reaOriginal Figure 5:We would like it to be corrected as shown below.1.New Figure 5:2.The result of Section 3.1. Clinicopathological Characteristics and Progression of Breast Cancer.A total of 264 LN+ patients, with a median age of 56 years.3.The result of Section 3.2. A Significant Correlation Among RNF8, SNAI1, and CDH1 mRNA Expression in Patients with Breast Cancer.SNAI1 showed a significant positive correlation .4.J. Clin. Investig.2009, 119, 1420\u20131428. http://doi.org/10.1172/jci39104.The right reference No. 6 is: Kalluri, R.; Weinberg, R.A. The basics of epithelial-mesenchymal transition. JPM for this error. The published version will be updated on the article webpage, with a reference to this correction notice.These changes do not change the results or conclusions of our paper. The authors would like to apologize to readers of"}
{"text": "Cell Death & Disease 10.1038/s41419-019-1748-1, published online 1 July 2019Correction to: The authors would like to correct Figs. The revised Fig. The revised Fig."}
{"text": "In the following article,2H2]\u2010glucose  and [U\u201013C]\u2010palmitate  were started using a Gemini PC2 Pump .After blood and air sampling, infusions of [6.6\u2010The authors apologise for the errors."}
{"text": "The Journal and Authors retract the 8 February 2021 article cited above for the following reasons provided by the Authors:Following publication, concerns were raised regarding the integrity of the images in the published figures. The authors failed to provide a satisfactory explanation during the investigation, which was conducted in accordance with Frontiers\u2019 policies.This retraction was approved by the Chief Editors of Frontiers in Oncology and the Chief Executive Editor of Frontiers. The authors agree to this retraction."}
{"text": "The authors have requested that the following changes be made to their paper .The original authors wish to add Dr. Amanda M. Fretts as a coauthor to this paper, as she was mistakenly left off in the original published version. Contributions by Dr. Fretts included study conceptualization, supervision, and revision/editing of the manuscript. She approved the final manuscript for publication during August 2020. Unfortunately, it was not recognized by the authors until after publication that Dr. Fretts had been mistakenly left off of the author list.We would like to apologize for any inconvenience caused to the authors and readers by this mistake. The published version will be updated on the article webpage, with reference to this notice."}
{"text": "We regret the unprofessional behavior of the authors involved.li06yh@126.com>Correspondence: Yinghao Li: <"}
{"text": "Proc. R. Soc. B288, 20210839. (Published online 28 July 2021) (doi:10.1098/rspb.2021.0839)Proc. R. Soc. B 288, 20210839. http://doi.org/10.1098/rspb.2021.0839In the paper Roi Harel, J. Carter Loftus and Margaret C. Crofoot 2021. Locomotor compromises maintain group cohesion in baboon troops on the move. The required change is to change the first institution for all of the authors from Department of Ecology, Evolution and Behavior, The Life Sciences Institute, The Hebrew University of Jerusalem, Givat Ram, Jerusalem 9190401, Israel to Department for the Ecology of Animal Societies, Max Planck Institute of Animal Behavior, B\u00fccklestra\u03b2e 5, Konstanz 78467, Germany."}
{"text": "In paper \u201cVISTO: An Open-Source Device to Measure Exposure Time in Psychological Experiments\u201d, a device that measures the onset of experimental visual stimuli is described. This device acquires luminance information through a light sensor BPW42, and then records luminance waveforms or onset times. Throughout the paper however, sensor BPW42 was erroneously described as a photodiode, while it is a phototransistor. Moreover, the wiring scheme in In the revised The authors would like to apologize for any inconvenience caused."}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive any reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors\u2019 attention by a concerned reader that certain of the Transwell cell migration data shown in Fig. 4C were strikingly similar to data appearing in different form in other articles by different authors. Owing to the fact that the contentious data in the above article had already been published elsewhere, or were already under consideration for publication, prior to its submission to"}
{"text": "The Journal and Authors retract the 9 September 2020 article cited above for the following reasons provided by the Authors:Following publication, concerns were raised regarding image manipulation. The authors failed to provide a satisfactory explanation during the investigation, which was conducted in accordance with Frontiers\u2019 policies.This retraction was approved by the Chief Editors of Frontiers in Oncology and Chief Executive Editor. The authors agree to this retraction."}
{"text": "Cell DiscoveryCorrection to: 10.1038/s41421-021-00281-2, published online 13 July 20211, we missed labeling the co-first authors. The first two authors, Jiayan Zhang and Hui Wang, who have contributed to this work equally, should have been designated with a footnote of \u201cThese authors contributed equally: Jiayan Zhang, Hui Wang\u201d. This correction does not affect the description of the results or the conclusion of this work.In the original publication of this Correspondence"}
{"text": "Furthermore, text for an Acknowledgments section for this paper has been added as follows:Acknowledgmentswww.pulsenotes.com).Note that the figure used in this review was reproduced with kind permission of The Pulsenotes Team (Oncology Letters regrets that this review was published without a proper acknowledgement being made to The Pulsenotes Team as the source of the figure, and the Journal is grateful to them for raising this matter with us as a concern. Furthermore, we apologize to The Pulsenotes Team for the inconvenience caused.These corrections have also been added to the published version of the paper. Note that the authors were also consulted, but the Editorial Office did not receive a timely response from them. The Editor of"}
{"text": "The authors also apologize to the readership for any inconvenience these errors may have caused.Consequently, the corrected versions of"}
{"text": "In our paper"}
{"text": "In particular, the authors became aware of these errors when they\u00a0prepared a webinar presentation in which they presented their validation work. The original Table 3 reported values for the tests performed\u00a0by operator # 1, for dilutions G and H, different from the original raw data. Furthermore, by reanalyzing all the data in this table, we noticed that all the standard deviation measurements were calculated incorrectly. These have now been corrected online. The authors regret this error."}
{"text": "Oxidative Medicine and Cellular Longevity has retracted the article titled \u201cStearoyl-CoA Desaturase 1 Potentiates Hypoxic plus Nutrient-Deprived Pancreatic Cancer Cell Ferroptosis Resistance\u201d [istance\u201d . SpecifiThe authors do not agree to the retraction."}
{"text": "Following publication of the original article , the autIncorrect2 Translational Oncology, National Center for Tumor Diseases, German Cancer Research Center, Heidelberg, GermanyBenedikt Brors affiliations\u20141,2,5Correct2 Division of Translational Medical Oncology, National Center for Tumor Diseases, German Cancer Research Center, Heidelberg, GermanyBenedikt Brors affiliations\u20141,5"}
{"text": "Dear Editor,In our publication  we stateThis statement is erroneous. Recently, it was pointed out to us that the Royal College of Obstetricians and Gynecologists of Canada Objectives of Training in the Specialty of Obstetrics and Gynecology were amended and include the following statement applicable after July 1, 2016:\u201cThe following procedures in List A are those that the fully trained resident in Obstetrics and Gynecology must be competent to perform independently: 5.2.2.41. Limited cystoscopy\u201dWe regret our error and apologise for any inconvenience.E-mail: gjacob2010@gmail.comG.P. Jacob, G.A. Vilos, F. Al Turki, G. Bhangav, B. Abu-Rafea, AG.. Vilos, A. Ternamian"}
{"text": "The authors regret that:The EPSRC grant number currently stated in Funding Source section is `EP/K030957/1', which is incorrect. The correct funding source is `EP/N024818/1'.The authors would like to apologise for any inconvenience caused."}
{"text": "There is an error in"}
{"text": "Sci., 2021, DOI: 10.1039/d0sc06186g.Correction for \u2018Rhodium-catalysed selective C\u2013C bond activation and borylation of cyclopropanes\u2019 by Yandong Wang  The authors regret that there were a few errors in I is the kinetically favoured product\u201d to the end of this paragraph should be corrected to \u201cFinally, the catalytic species A is regenerated via dissociation of 12 or E13- from the Rh center. The enamide E13- is the kinetically favoured product, which supports the observation of 13 in Scheme 3A-3, where HBpin is not added.\u201dOn pages 6\u20137 of the original manuscript, the sentences from \u201cThe enamide These changes do not alter the scientific conclusions of the manuscript.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "After having been in contact with the authors, they agreed with the decision to retract the paper. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors attention by a concerned reader that certain of the flow cytometric and western blotting data shown in Fig. 3A and C respectively, and the tumor images shown in Fig. 7A, bore unexpected similarities to data appearing in different form in other articles by different authors. Owing to the fact that some of the contentious data in the above article had already been published elsewhere, or were already under consideration for publication, prior to its submission to"}
{"text": "Sci., 2020, 11, 12731\u201312736, DOI: 10.1039/D0SC02351E.Correction for \u2018On the electronic structure and hydrogen evolution reaction activity of platinum group metal-based high-entropy-alloy nanoparticles\u2019 by Dongshuang Wu  The authors regret that there was an error in The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "The dates for the cohort of people with 1 or more office-based addiction treatment encounters given as \u201cJanuary 1\u201d and \u201cDecember 21, 2018,\u201d should have been \u201cJanuary 1, 2008,\u201d and December 31, 2018.\u201d This article has been corrected.1In the Original Investigation titled \u201cOffice-Based Addiction Treatment Retention and Mortality Among People Experiencing Homelessness,\u201d"}
{"text": "Sci., 2014, 5, 4474\u20134482, DOI: 10.1039/C4SC01605J.Correction for \u2018Hydrogen-activation mechanism of [Fe] hydrogenase revealed by multi-scale modeling\u2019 by Arndt Robert Finkelmann  In p and the oxypyridine O atom was given as 1.82 \u00c5 and the distance between Hp and the Fe atom was given as 1.7 \u00c5. However, it should read 1.82 \u00c5 between Hp and Fe and 1.70 \u00c5 between Hp and the oxypyridine O atom. In p and Fe was shown to be 1.70 \u00c5 and the distance between Hd and Fe was given as 1.73 \u00c5. However, it should read 1.73 \u00c5 between Hp and Fe and 1.70 \u00c5 between Hd and Fe. The correct versions of these figures are given below. The results and conclusions are not affected by these typographical errors.The authors regret that there were minor typographical errors in two figures. In The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "The Editorial Office has been unable to confirm such findings directly with authorities at the institution in accordance with standard practice. Given the nature of the concerns raised, the Editor-in-Chief wishes to alert the readers to interpret the results presented here with caution.Corresponding authors Insug Kang and Eui-Ju Yeo stated on behalf of all co-authors that they agree to this Expression of Concern."}
{"text": "Furthermore, flow cytometric data featured in Fig. 2D were strikingly similar to those in another previously published paper, and cell cyle data included in Fig. 3 had apparently previously published elsewhere.Owing to the fact that the contentious data in the above article had already appeared in different form in other articles prior to its submission to Molecular Medicine Reports, the Editor has decided that this paper should be retracted from the Journal. The authors also expressed their intention to retract the paper on the grounds that the corresponding author and several of the authors failed to confirm the approval of the final version of the manuscript. The Editor apologizes to the readership for any inconvenience caused."}
{"text": "The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates."}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office never received any reply. The Editor regrets any inconvenience that has been caused to the readership of the Journal.After having conducted an independent investigation in the Editorial Office, the Editor of"}
{"text": "Sci., 2021, 12, 14432\u201314440, DOI: 10.1039/d1sc04138j.Correction for \u2018Plasticizer and catalyst co-functionalized PEDOT:PSS enables stretchable electrochemical sensing of living cells\u2019 by Jing Yan  The authors regret that there was an error in the equation of the calibration curve of PPL/PDMS in The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Following the publication of this article, the authors have reaized that Table II was printed containing certain numerical errors, although these were not significant enough to have affected the statistical results.Oncology Letters for allowing them the opportunity to publish this corrigendum, and all the authors agree to this corrigendum. Furthermore, the authors apologize to the readership for any inconvenience caused.The corrected version of Table II is shown on the next page, and the corrected data  are highlighted in bold. The authors are grateful to the Editor of"}
{"text": "The affiliation of the corresponding author Sharon A. Tooze to the Institute of Cancer Research, Olso, Norway was incorrectly added. The authors would like to apologize for any inconvenience caused."}
{"text": "The authors regret that in the original article an incorrect email address was given for the corresponding author Sang-Wha Lee. The correct email address is shown here.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Dauncey et al., Chem. Sci., 2019, 10, 7728\u20137733.Correction for \u2018A dual photoredox-nickel strategy for remote functionalization  The authors regret that The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "CLINICS (Sao Paulo). 2021;76:e1512errhttps://doi.org/10.6061/clinics/2020/e1512, published in 2020.Erratum for: doi: Randomized trial of physiotherapy and hypertonic saline techniques for sputum induction in asthmatic children and adolescentsIn the article \u201cKarina Pierantozzi Verganid\u201d for: \u201cKarina Pierantozzi Vergani\u201dReplace and Page 6 \u2013 AUTHOR CONTRIBUTIONS\u201cVerganid KP\u201d replace for \u201cVergani KP\u201dwhere it reads"}
{"text": "The tenth and eleventh authors, Dante R. Culqui and Joan A. Cayl\u00e0, should be noted as joint senior authors of this work. The publisher apologizes for the error."}
{"text": "Sci., 2020, 11, 6907\u20136914, DOI: 10.1039/D0SC02717K.Correction for \u2018Effect of heterocycle content on metal binding isostere coordination\u2019 by Benjamin L. Dick  The authors regret that a complete Conflicts of interest section was not shown in the original article. The correct Conflicts of interest section is shown below.The authors declare the following competing financial interest(s): S. M. C. is a co-founder of and has an equity interest in Cleave Therapeutics, Forge Therapeutics, and Blacksmith Medicines, companies that may potentially benefit from the research results. S. M. C. also serves on the Scientific Advisory Board for Blacksmith Medicines and serves on the Scientific Advisory Board and receives compensation from Forge Therapeutics. The terms of this arrangement have been reviewed and approved by the University of California, San Diego in accordance with its conflict of interest policies.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a satisfactory reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors\u2019 attention by a concerned reader that certain of the western blot assay data shown in Figs. 1C and 6A were strikingly similar to data appearing in different form in another article written by different authors. Owing to the fact that the contentious data in the above article were already under consideration for publication prior to its submission to"}
{"text": "The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates."}
{"text": "After having been in contact with the authors, they agreed with the decision to retract the paper. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors\u2019 attention by a concerned reader that the western blot assay data shown in Figs. 1B, 5A, 6A and C were strikingly similar to data appearing in different form in other articles by different authors. Owing to the fact that the contentious data in the above article were already under consideration for publication prior to its submission to"}
{"text": "Retraction to: BMC Complement Altern Med 17, 458 (2017)https://doi.org/10.1186/s12906-017-1958-yIn Fig.\u00a02 it appears that \u2018Control Positive\u2019 and \u2018Leaf\u2019 show the same image and that \u2018Bark\u2019 and \u2018Root\u2019 show the same imageIn Fig.\u00a05 it appears that \u2018CH Leaves\u2019 and \u2018CH Bark\u2019 show the same image, albeit rotatedIn Fig.\u00a05 it appears that \u2018CH Flowers\u2019 and \u2018EA Bark\u2019 show the same image, albeit rotatedIn Fig.\u00a05 it appears that \u2018HE Bark\u2019 and \u2018EA Roots\u2019 show the same image, albeit rotatedIn Fig.\u00a05 it appears that \u2018EA Flowers\u2019 and \u2018HE Roots\u2019 shows the same imageThe Editor in Chief has retracted this article  because The authors provided additional data, but were not able to show original images for these figures. The Editor-in-Chief therefore no longer has confidence in the integrity of the data in this article.Both authors, P.V.V. Satish and K. Sunita have not explicitly stated whether they agree to this retraction notice."}
{"text": "VOLUME 293 (2018) PAGES 19025\u201319037D, the PLA images forXPA-WT, XPA-K63Q, and XPA-K67Q were duplicated. Also inFig.\u00a03D, the DAPI merged images for XPA-WT and XPA-K63Qwere duplicated.This article has been withdrawn by the authors except StuartJarrett, who could not be reached. The withdrawing authors were unable to provideoriginal data corresponding to many of the micrographs presented in the articleaccording to Journal policy. In Fig.\u00a03"}
{"text": "After having been in contact with the authors, they agreed with the decision to retract the paper. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors\u2019 attention by a concerned reader that the western blotting data in Figs. 3 and 6 were strikingly similar to data appearing in different form in other articles by different authors at different research institutes. Owing to the fact that the contentious data in the above article were already under consideration for publication, or had already been published, elsewhere prior to its submission to"}
{"text": "The authors regret to acknowledge financial support from Ministerio de Ciencia e Innovaci\u00f3n (MCI), Agencia Estatal de Investigaci\u00f3n (AEI) and Fondo Europeo de Desarrollo Regional (FEDER) through MOCCA Project (RTI2018-093941-B-C31).The authors would like to apologise for any inconvenience caused."}
{"text": "Following publication, concerns were raised regarding image manipulation. The authors failed to provide a satisfactory explanation during the investigation, which was conducted in accordance with Frontiers' guidelines.This retraction was approved by the Chief Editors of Frontiers in Cellular and Development and the Editor-in-Chief of Frontiers. The authors [did] agree to this retraction."}
{"text": "There is an error in the affiliations for authors Miraine D\u00e1vila Felipe and Olivier Gascuel. Neither author should have a current address listed and both authors have two affiliations.Both authors are affiliated to #1: Unit\u00e9 Bioinformatique Evolutive, D\u00e9partement de Biologie Computationelle, Institut Pasteur, Paris, France.The correct second affiliation for Miraine D\u00e1vila Felipe is: Universit\u00e9 de technologie de Compi\u00e8gne, LMAC (Laboratory of Applied Mathematics of Compi\u00e8gne), Compi\u00e8gne, France.The correct second affiliation for Olivier Gascuel is: Institut de Syst\u00e9matique, Evolution, Biodiversit\u00e9 , Paris, France."}
{"text": "Ms. Jill Harris has requested that she should be removed from the list of contributing authors. After re-considering her contribution, we wish to remove her from the authorship of our paper  and add"}
{"text": "There is an error in the Conclusion subsection of the Abstract. The correct sentence is: A low autonomic nervous system activity, i.e. low SDNN or Energy, and a predominance of the parasympathetic system, i.e. high HFnu or ANIm, due to the sympathetic depletion in COVID-19 patients are associated with a worse prognosis, higher mortality, and higher IL-6 levels."}
{"text": "The authors regret that the affiliations of three of the authors  were shown incorrectly in the original article. The corrected author list and affiliations are as shown above.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "The authors state that the images used in the original"}
{"text": "Sci., 2023, https://doi.org/10.1039/D2SC05051J.Correction for \u2018Bond breaking of furan\u2013maleimide adducts  The authors regret that a typo in the corresponding author designation in the list of authors, appeared in the original manuscript. The corrected list of authors for this paper is as shown above.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Behavioral Ecology, Volume 30, Issue 2, March/April 2019, Pages 348\u2013355, https://doi.org/10.1093/beheco/ary171This is an Expression of Concern regarding: Molly M Ashur, Danielle L Dixson, Multiple environmental cues impact habitat choice during nocturnal homing of specialized reef shrimp, The Editor-in-Chief has been alerted to concerns about the credibility of the data in the above paper.The journal is publishing this Expression of Concern to alert readers while we investigate to determine whether further action is required."}
{"text": "Unfortunately, the authors could not provide the original data, despite the paper being published so recently. The authors re-analysed their samples and supplied cropped replicate blots and analyses, stating that these results support the conclusions of the paper.The journal concluded that without the original data for the published figures, we have no option but to retract this paper. This course of action follows the advice set out by COPE (Committee on Publication Ethics), of which Biology Open is a member.The authors did not respond to say whether they agree with this retraction."}
{"text": "Communications Biology 10.1038/s42003-022-03193-3, published online 15 March 2022.Correction to: In this Q&A the affiliation details for Victor Garcia were incorrectly given as \u201cAssociate Professor at New York Medical College\u201d but should have been \u201cAssistant Professor at New York Medical College\u201d.Both errors have now been corrected in the HTML and PDF versions of the Q&A."}
{"text": "Increases in life expectancy over the last 50 years has been matched by an increase in the burden of diseases (e.g. herpes zoster (HZ)) in adults \u226550 years of age (YOA). Without intervention, around 30% of individuals can expect to develop HZ in their lifetime, which would impact their daily activities and healthy ageing.We conducted a narrative review on published literature on the impact of developing HZ on healthy ageing and the ability of vaccination to prevent the burden of disease due to HZ. Specifically, we describe HZ impact on quality of life (QoL), and impact of the adjuvanted recombinant zoster vaccine (RZV) on reducing the burden of HZ in adults \u226550 YOA.In adults \u226550 YOA with HZ, 65.1% and 15.8% reported severe pain and worst imaginable pain, respectively. Pain persisted for up to 90 days  in 10-20% of HZ patients, and occasionally for years after initial symptoms. Pain due to HZ impacted all domains of QoL . Evidence suggested that RZV reduced HZ burden of illness and burden of interference on daily activities by > 90%. Reports also suggested that RZV retained vaccine efficacy of > 90% in all frailty subgroups, who typically respond poorly to other vaccinations. Long-term follow-up data reported vaccine efficacy against HZ of 84.1% , 8 years post-vaccination. Modelling studies demonstrated that vaccination resulted in reduced hospitalization and other healthcare visits related to HZ.Vaccination with RZV can protect older adults from HZ, thus maintaining QoL and promoting active and healthy ageing.\u2022\u2002There is significant burden of disease due to HZ among adults \u226550 YOA due to ageing and immunosenescence.\u2022\u2002Vaccination can reduce burden of disease among the elderly and frail individuals and maintain QoL."}
{"text": "Ind. Crop & Prod. A,1 which should have been cited in this RSC Advances paper.The authors wish to draw the readers\u2019 attention to their closely related paper, in The authors regret the unattributed text, figure and data overlap between their article and ref. 1. Table 1, Fig. 2, Fig. 3 and Table 2 were re-used in part or in full from ref. 1 without being correctly attributed and without permission from the Publisher.The authors have now received the permission to reuse the images and the corrected captions are shown below:Ind. Crops Prod., 2015, 74, 417\u2013424, with permission from Elsevier.Table 1 Effect of SW water extractives on the mechanical performance of gypsum. Reprinted in part from Dasong Dai and Mizi Fan, \u2018Preparation of bio-composite from wood sawdust and gypsum\u2019, Ind. Crops Prod., 2015, 74, 417\u2013424, with permission from Elsevier.Fig. 2 ATR-FTIR spectra of WBE coating SW, raw SW and subtraction from the surface of WBE coating SW. Reprinted from Dasong Dai and Mizi Fan, \u2018Preparation of bio-composite from wood sawdust and gypsum\u2019, Ind. Crops Prod., 2015, 74, 417\u2013424, with permission from Elsevier.Fig. 3 Matching result of subtraction from the surface of WBE coating sawdust with OMNIC software. Reprinted from Dasong Dai and Mizi Fan, \u2018Preparation of bio-composite from wood sawdust and gypsum\u2019, Ind. Crops Prod., 2015, 74, 417\u2013424, with permission from Elsevier.Table 2 Effect of SW modification on the mechanical performance of gypsum/SW composite (with ultrasonic pretreatment). Reprinted in part from Dasong Dai and Mizi Fan, \u2018Preparation of bio-composite from wood sawdust and gypsum\u2019, The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "The journal retracts the 22 August 2019, article cited above.Following publication, concerns were raised regarding the substantial similarity of content with two of the authors\u2019 previous publications. An investigation was conducted in accordance with Frontiers\u2019 policies, whereby it was confirmed that the degree of reuse of the previously published content is inconsistent with our editorial requirements for originality. Following the Committee on Publication Ethics guidelines, this article, published most recently, is retracted. This retraction was approved by the Chief Editors of Frontiers in Pharmacology, and the Chief Executive Editor of Frontiers. The authors agree to this retraction.The authors concur with the retraction and sincerely regret any inconvenience this may have caused to the reviewers, editors, and readers of Frontiers in Pharmacology."}
{"text": "Journal of Healthcare Engineering has retracted the article titled \u201cThe Potential Mechanism of Exercise Combined with Natural Extracts to Prevent and Treat Postmenopausal Osteoporosis\u201d [porosis\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifiThe authors do not agree to the retraction."}
{"text": "One microscopic image of tissue sections of the mouse brain in Fig. S5 (Supplementary Files) was chosen incorrectly due to wrong data naming. We have performed the histological examination again to ensure scientific rigor in this work. The newly arranged Fig. S5 is as follows. Notably, the correction does not affect the main conclusion of our paper. We genuinely apologize to the Editor and the readership of the journal for any inconvenience it caused."}
{"text": "N-(6-(4-(pyrazine-2-carbonyl)piperazine/homopiperazine-1-yl)pyridin-3-yl)benzamide derivatives as anti-tubercular agents\u2019 by Singireddi Srinivasarao et al., RSC Adv., 2020, 10, 12272\u201312288, DOI: 10.1039/D0RA01348J.Correction for \u2018Seeking potent anti-tubercular agents: design and synthesis of substituted- The authors regret that the name of one of the authors (Linda De Vooght) was shown incorrectly in the original article. The corrected author list is as shown above.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "A new MRI examination showed a persistent lack of enhancement and involvement of U-fibers (A 78-year-old man was admitted to the emergency department because of disorientation, gait imbalance, and dysarthria for 3 weeks. Brain ic edema . LaboratU-fibers . Based o"}
{"text": "The authors regret that an incorrect figure caption was given for The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "The authors regret that the affiliations were incorrectly shown in the original manuscript. The corrected list of affiliations is as shown above.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "The following information is missing from the Competing Interests statement:PLOS ONE policies on sharing data and materials.Dr. Harald Matthes is a member of the board of directors at Weleda AG, a company that until 2016 distributed Iscador, a mistletoe preparation. In addition, Dr. Harald Matthes is a member of the board of the Hufelandgesellschaft e. V. in Germany; President of the DAHN (German Academy for Homeopathy and Naturopathy); and medical director and managing director of Gemeinschaftskrankenhaus Havelh\u00f6he, a hospital for anthroposophic medicine. Dr. Harald Matthes is also a recipient on an endowed professorship from Charit\u00e9 in Berlin on Integrative and Anthroposophical Medicine. These competing interests do not alter the authors\u2019 adherence to"}
{"text": "The authors regret a mistake in the author names of ref. 44. The correct reference is shown below as ref. The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Independently of the reader's enquiry, the authors contacted the Editorial Office to request that the paper be retracted on account of the fact that they were unable to reproduce the results presented in Fig. 2.Oncology Reports, and in line with the authors' own request, the Editor has decided that this paper should be retracted from the Journal. The Editor apologizes to the readership for any inconvenience caused.Owing to the fact that the contentious data in the above article were already under consideration for publication, or had already been published, elsewhere when it was submitted to"}
{"text": "Sci., 2021, 14, 2335\u20132348; DOI: 10.1039/D0EE02984J.Correction for \u2018Optimizing accuracy and efficacy in data-driven materials discovery for the solar production of hydrogen\u2019 by Yihuang Xiong  The following funding source was missing from the Acknowledgments section:The National Science Foundation through the Research Experiences for Undergraduates and Research Experiences for Teachers in Nanoscale Physics and Materials at Pennsylvania State University under Grant No., DMR142062 and DMR2011839.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "The text should read \u201cThe precursor glass (PG) compositions (mol%) is 17.5 KF-17.5 ZnFThe Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "The identification of causative genetic variants for hereditary diseases has revolutionized clinical medicine and an extensive collaborative framework with international cooperation has become a global trend to understand rare disorders. The Initiative on Rare and Undiagnosed Diseases (IRUD) was established in Japan to provide accurate diagnosis, discover causes, and ultimately provide cures for rare and undiagnosed diseases. The fundamental IRUD system consists of three pillars: IRUD diagnostic coordination, analysis centers (IRUD-ACs), and a data center (IRUD-DC). IRUD diagnostic coordination consists of clinical centers (IRUD-CLs) and clinical specialty subgroups (IRUD-CSSs). In addition, the IRUD coordinating center (IRUD-CC) manages the entire IRUD system and temporarily operates the IRUD resource center (IRUD-RC). By the end of March 2021, 6301 pedigrees consisting of 18,136 individuals were registered in the IRUD. The whole-exome sequencing method was completed in 5136 pedigrees, and a final diagnosis was established in 2247 pedigrees (43.8%). The total number of aberrated genes and pathogenic variants was 657 and 1718, among which 1113 (64.8%) were novel. In addition, 39 novel disease entities or phenotypes with 41 aberrated genes were identified. The 6-year endeavor of IRUD has been an overwhelming success, establishing an all-Japan comprehensive diagnostic and research system covering all geographic areas and clinical specialties/subspecialties. IRUD has accurately diagnosed diseases, identified novel aberrated genes or disease entities, discovered many candidate genes, and enriched phenotypic and pathogenic variant databases. Further promotion of the IRUD is essential for determining causes and developing cures for rare and undiagnosed diseases. Identification of the causative genetic variants of hereditary diseases has revolutionized clinical medicine to enhance diagnostic accuracy, understand disease pathogenesis, and develop therapies. The major technical breakthrough behind the revolution was the development of whole-genome sequencing (WGS) and whole-exome sequencing (WES) methods employing next-generation sequencing (NGS), enabling identification of causative genetic variants by simultaneously capturing all candidate variants potentially causing diseases in affected individuals. Additionally, tremendous amounts of variant data have been generated using sequencers and remarkable advances have been made in bioinformatics exploiting such big data with powerful computational data analysis methods. Accumulation of variant data via registration in public databases has also accelerated the discovery of pathogenic variants by filtering known variants that are not associated with diseases.https://www.omim.org/), 9514 hereditary diseases were registered as of November 2021, of which 3288 diseases with (suspected) Mendelian basis are classified as having an unknown molecular basis. A complete understanding of the molecular basis of these diseases is one of the ultimate goals of human molecular genetics, which remains highly challenging even in the NGS era. The difficulty lies in identifying multiple pedigrees with pathogenic variants in the same genes to verify causality, particularly when researchers attempt to discover causative genetic variants for ultra-rare diseases, which are thought to comprise most unsolved diseases [However, there still remain many diseases for which causative genetic variants have not been identified. According to Online Mendelian Inheritance in Man (OMIM) (URL: https://irdirc.org/about-us/history/) established a worldwide network to connect individual projects to conduct international collaborative studies, further promoting the discovery of causative genetic variants [To solve the N-of-1 problem, the formation of extensive collaborative frameworks with international cooperation has become a global trend . The Undvariants . In 2015variants  and set variants . Furthervariants . One of variants . MME adovariants  and faciEven when causative genetic variants have been established, genetic diagnosis of rare diseases remains difficult in clinical settings. One reason for this is that a limited number of patients undergo WGS- or WES-based genetic diagnosis. Accessibility is among the key factors that can drive the utilization of this innovative technology in clinical genetics, necessitating a nationwide infrastructure to regionally equalize this testing. Additionally, determining pathogenic variants among a large number of variants yielded by WGS/WES and establishing the final diagnosis in which the pathogenic variants fully account for clinical manifestations is labor-intensive. Particularly, a substantial number of rare and undiagnosed diseases present with complex phenotypes with multiple affected organs, making the determination difficult by researchers in a single specialty. Therefore, it is recommended that diagnostic boards composed of physicians with a wide range of specialties and geneticists should discuss the final diagnosis based on the phenotypes and WGS/WES data.Enhancing the diagnostic accuracy of rare diseases has been vigorously pursued in Japan. Remarkable achievements have been made in the research and countermeasures for rare and intractable diseases, designated as \u201cNan-byo,\u201d by the Ministry of Health, Labor and Welfare in Japan, which was established in 1972 after the subacute myelo-optic neuropathy endemic. In 2015, a new intractable disease law was enforced to expand \u201cNan-byo\u201d from 56 to 333 diseases, further promoting the diagnosis of rare and intractable diseases. Nevertheless, two surveys conducted by AMED showed that more than 37,000 cases remained undiagnosed .To address these issues, the Initiative on Rare and Undiagnosed Diseases (IRUD) was launched in 2015 as a nationwide project in Japan supported by AMED . IRUD aiThe IRUD entry criteria are as follows .1. The patient remains undiagnosed for \u22656 months (not necessary for infants) and suffers from disabilities in daily life, AND2\u20131. Objective signs exist that cannot be attributed to a single organ; OR2\u20132. Direct or indirect evidence exists of a genetic etiology (e.g. similar symptom(s) found in the patient\u2019s relatives) .Here, an undiagnosed disease is clearly distinguished from an undetermined disease in which a clinical diagnosis has been made but its causative genetic variants have not been confirmed. For example, if spinocerebellar degeneration is clinically diagnosed, although its causative genetic variants have not been analyzed and disease type has not been determined, it is classified as an undetermined disease and excluded from the IRUD. This clearly distinguishes the IRUD from genetic diagnostic services.https://annovar.openbioinformatics.org/) together with RefSeq (http://www.ncbi.nlm.nih.gov/RefSeq/), 1000 Genomes Project Database (http://www.1000genomes.org/), dbSNP135 (http://www.ncbi.nlm.nih.gov/projects/SNP/), gnomAD (http://www.gnomad.broadinstitute.org), and in-house databases.Blood samples were obtained from the participants fulfilling the criteria mentioned above with informed consent, DNA samples were extracted, and B-cell lymphoblast cell lines were established. Genomic DNA was subjected to enrichment of exonic sequences using Agilent SureSelect . Massively parallel sequencing (100-base pair paired-end reads) was performed using NGS . The sequences were aligned to the reference genome (GRCh37/hg19) using the Burrows-Wheeler Aligner or NovoAlign. Removal of potential polymerase chain reaction duplicates, recalibration of base quality values, local realignment, and variation calls were performed using SAMtools, Picard, and GATK with default parameter settings for alignment of raw reads and detection of single-nucleotide variants and short insertion/deletion variants. These variants were annotated using ANNOVAR  was established in IRUD-A as one of the leading model projects in AMED to facilitate the ethical review process in multi-institutional large-scale collaborative research. All but one of the individual institutional ethical committees in IRUD-A delegated the reviewing process to the CEC. The delegation process had been further promoted upon the integration of IRUD-A and IRUD-P.A unified research protocol for IRUD was reviewed and approved by the CEC. The ethics committee of individual institutions delegated the review process to the CEC, where approval of the protocol allowed each institute to initiate IRUD research based on the unified protocol. Amendment of the unified protocol, such as authentication of newly participating institutes, is accomplished in a one-step review process as an entire IRUD project. This study was approved by the CEC at Tohoku University on February 20, 2018 (CEC No. 2017-2-303).The most important achievement of IRUD is establishment of a unified all-Japan diagnostic and research system for rare and undiagnosed diseases covering entire geographic areas and clinical specialty/subspecialty fields. The IRUD system consists of three pillars: IRUD diagnostic coordination, analysis centers (IRUD-ACs), and a data center (IRUD-DC). IRUD diagnostic coordination consists of clinical centers (IRUD-CLs) and clinical specialty subgroups (IRUD-CSSs). In addition, the IRUD coordinating center (IRUD-CC) manages the entire IRUD system and temporarily operates the IRUD Resource Center (IRUD-RC) Fig.\u00a0.Fig. 1InThe principal role of IRUD-CC is administration of the whole system through monthly IRUD-PB meetings as the highest decision-making organization. The constituents of IRUD-PB include representatives of the IRUD-CC , AMED (program officers) as the funding agency, IRUD-CLs, IRUD-CSSs, IRUD-ACs, and IRUD-DCs. IRUD-CC drafts a unified research protocol that is ratified by IRUD-PB and subjected to CEC, with the one-step approval process contributing to timely modification of the IRUD research. In addition, IRUD-CC monitors the progress of the entire research by conducting a regular survey. IRUD-CC also operates the sample and information logistics system described in detail in a subsequent section.IRUD-CL/SCL is the only contact site for patients with IRUD. Upon patient entry, parents are recruited so that trio analysis can be performed. IRUD-CL/SCL operates the IRUD Diagnostic Board (IRUD-DB), which manages the process from patient entry decisions to final diagnosis establishment. IRUD-SCLs are designed to fill the geographic gaps of IRUD-CLs, although no funding was provided. IRUD Cooperative Hospitals refer candidates for IRUD entry to IRUD-CL/IRUD-SCL. The IRUD-DB plays a central role in the regional diagnostic network with IRUD Cooperative Hospitals. The IRUD-DB is composed of pediatricians and physicians of various specialties/subspecialties for adults, clinical geneticists, genetic counselors, and data scientists. The IRUD protocol stipulates the participation of representative physicians from local medical associations in each IRUD-DB to promote regional cooperation.IRUD-DB holds regular meetings during which thorough pre-entry evaluation is conducted based on the clinical information described in a regular format on a \u2018patient sheet\u2019 to determine whether the candidate is suitable for IRUD entry and if sufficient investigation has already been completed, including whether clinical workups and available genetic tests such as chromosome analysis or gene-panel analysis have been performed. Similarly, post-analysis evaluation is conducted at the regular meetings to determine whether the pathogenic variant reported by IRUD-AC fully accounts for the clinical phenotypes leading to the final clinical diagnosis. In addition, the activities of the IRUD-DB include genetic counseling, further follow-up and reevaluation of the pedigree, public relations, and human resource development. Thus, IRUD-CL/SCL plays an essential role in the clinical aspects of the IRUD system.IRUD-CSSs are organized by assembling members of IRUD-DBs across entire IRUD-CLs according to their specialties/subspecialties. IRUD-CSSs support the activities of individual IRUD-DBs and provide professional advice based on their specialties/subspecialties for cases that cannot be resolved by IRUD-CLs alone.Thus, IRUD-CLs and IRUD-CSSs form the IRUD Diagnostic Coordination covering entire geographic areas and specialty/subspecialty fields in Japan.Each IRUD-CL/IRUD-SCL sends DNA samples via an outsourcing provider to a corresponding single IRUD-AC, which conducts comprehensive genomic analysis, identifies pathogenic variants, and reports to the IRUD-CL/IRUD-SCL via the IRUD-CC. When pathogenic variants are undetermined, further intensive research is conducted to identify novel aberrated genes/pathogenic variants using WGS, multi-omics analysis, and functional studies.IRUD-DC operates the IRUD Exchange, the data-sharing platform described above, promotes data sharing among IRUD researchers, and serves as a gateway to domestic and international collaboration. Phenotypic and genomic information has been accumulated to promote the establishment of new causative genetic variants and disease concepts. The IRUD Exchange is also used as a database to understand the overall epidemiological landscape of rare and undiagnosed diseases registered in the IRUD. All IRUD-CLs and IRUD-SCLs have a computer terminal for the IRUD-Exchange, and phenotypic and genotype data are transferred to IRUD-DC through a specific virtual private network to ensure security.IRUD-RC establishes a resource repository for clinical information and DNA samples/B cell lines and manages a utilization committee for examining the utilization of repositories. The IRUD-CC temporarily serves as the IRUD-RC, which is planned to be established as an independent facility assigned by AMED.IRUD-CC organizes a unified workflow to facilitate sample and information sharing among the IRUD-CLs/IRUD-SCLs, IRUD-ACs, and IRUD-CC and establishes a centralized repository in IRUD-RC Fig.\u00a0.Fig. 2SaUpon entry into the IRUD, an individual identification (ID) number, composed of a three-alphabetical institutional code and five-digit numerical number, is allotted to each registrant, whose DNA/cell line samples, clinical information, and analysis results are handled with a specific ID. The workflow utilizes an outsourcing provider to extract genomic DNA samples and establish B lymphoblast cell lines. The genomic DNA samples are sent to the IRUD-ACs and IRUD-CC, and B lymphoblast cell lines are sent to the IRUD-CC. Each IRUD-CL/IRUD-SCL sends the samples to a specific IRUD-AC designated by IRUD-CC. Clinical information in the form of a \u2018patient sheet\u2019 is also sent to IRUD-ACs via an outsourcing provider. The analysis results and clinical information are sent from the IRUD-ACs to the IRUD-CC and reported to the corresponding IRUD-CLs. Clinical information is accumulated in the IRUD-DC through IRUD-Exchange from the IRUD-CLs. Text-based clinical data on the patient sheet delivered from the IRUD-CL/SCL via the IRUD-AC and analysis reports delivered from the IRUD-AC are also stored in the IRUD-CC. Genomic DNA samples and B lymphoblast cell lines are deposited in the IRUD-RC.In March 2021, the IRUD diagnostic system comprised 450 institutions consisting of 37 IRUD-CLs, 15 IRUD-SCLs, and 398 cooperative hospitals  Fig.\u00a0. Among ties Fig.\u00a0 . Particularly, approximately one-half of pedigrees with an established diagnosis possess unique aberrated genes. Importantly, such diseases are individually \u2018ultra-rare\u2019 but not as a whole, necessitating further vigorous endeavors to provide accurate diagnosis and develop therapeutic measures for individual \u2018ultra-rare\u2019 diseases.The IRUD has established an accurate diagnosis for a large number of patients and, in some cases, led to the use of specific therapies with positive effects . Pathogehttps://www.ncbi.nlm.nih.gov/clinvar/), LOVD (https://www.lovd.nl/), and MGeND (https://mgend.med.kyoto-u.ac.jp/) as well as disease databases such as OMIM and Orphanet (https://www.orpha.net/).The IRUD has had important impacts on basic research by identifying many novel aberrated genes, establishing novel disease entities, and detecting novel pathogenic variants in known aberrated genes. Disease-causing genes are the most reliable pathogenic molecules with greatest impact on the development, course and prognosis of the disease. Identification of these genes has led to an increased understanding of disease pathogenesis and identification of druggable seeds, promoting research of rare and undiagnosed diseases, common diseases, and human physiology. Furthermore, the IRUD has greatly contributed to genomic medicine by identifying a large number of novel pathogenic variants in known aberrated genes. Approximately two-thirds of the identified pathogenic variants were novel, supporting the indispensable role of the IRUD in genomic medicine in addition to its diagnostic services. Aggregation of phenotypic and pathogenic variant data can enrich variant databases such as ClinVar (https://www.matchmakerexchange.org/participants.html). The collaboration network provides a collective dataset spanning more than 150,000 cases from more than 11,000 contributors in 88 countries [A remarkable feature of the IRUD is the extensive data sharing through the IRUD Exchange, which has accumulated HPO-based phenotypic and genetic data to enable searches for similar cases automatically by pattern-matching algorithms and solving N-of-1 problems. The IRUD Exchange is compatible with MME and functions as a gateway to domestic and international collaborative networks. The IRUD is one of the principal eight nodes of international genomic research projects connected via the MME . Activities in the IRUD encompass entire fields of genome medicine or research, including phenotyping, genetic analysis, informatics, diagnosis, and counseling. Experiences in the IRUD would be of great help in individual career development. The IRUD also provides excellent educational opportunities for medical geneticists, genetic counselors, and data scientists. Therefore, the IRUD is not only a nationwide diagnostic and research system, but also a sustainable human resource development system in Japan.Notwithstanding the exhaustive WES, nearly 3000 pedigrees remained undiagnosed. Particularly, 313 pedigrees belonged to the N-of-1 category, for which discovery of another pedigree with the same candidate genes should be definitely necessary. Further promotion of international collaboration is the key to address the N-of-1 issue. On top of that, reasons for the undetermined causes are thought to include mosaicism, genomic alterations, gene regulation, and complex inheritance, all of which are difficult to capture by WES . To addrList of genes and number of novel and known pathogenic variantsNovel genes and phenotypes"}
{"text": "Note that all the authors agree with the decision to retract this article. The Editor and the authors regret any inconvenience that this retraction will cause to the readership of the Journal.The Editor of"}
{"text": "DOI: 10.1039/C5RA25870GRetraction of \u2018CuS nanocrystal@microgel nanocomposites for light-regulated release of dual-drugs and chemo-photothermal synergistic therapy  The Royal Society of Chemistry hereby wholly retracts this RSC Advances article due to concerns with the reliability of the data in the published article.The TEM image in Fig. 1c contains duplicating features and inconsistencies within the image, which indicates that it has been manipulated.Given the significance of the concern about the validity of the data, the findings presented in this paper are no longer reliable.Jie Sun, Rijun Gui, Hui Jin, Na Li and Xiaojing Wang state that Fig. 1c has not been manipulated but have not been able to provide any satisfactory raw data to confirm its authenticity. The authors oppose the decision to retract.Signed: Laura Fisher, Executive Editor, RSC Advancesst September 2020Date: 21"}
{"text": "The authors would like to make corrections to a recently published paper .In the original publication, the funder German Research Foundation (Deutsche Forschungsgemeinschaft), DFG FOR 2959, project-id: 409800133; grant number: DI 1757/2-1 to authors Jonas Lander and Marie-Luise Dierks was not included. The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. The original publication has also been updated."}
{"text": "The authors wish to make the following corrections to this paper :After the publication of the manuscript, the authors recognized an error in the second paragraph of Section 3.1. The Trial Demonstrated PCV13 Efficacy for Prevention of First Episodes of VT CAP, Nonbacteremic/Noninvasive VT CAP and VT IPD. In the published version, it was stated that \u201cFor VT CAP, NB/NI VT CAP, and VT IPD, respectively, PCV13 demonstrated similar efficacy in the mITT population for first VT episodes  and all VT episodes  [29].\u201dTo the correct version, as follows:\u201cFor VT CAP, NB/NI VT CAP, and VT IPD, respectively, PCV13 demonstrated similar efficacy in the mITT population for first VT episodes  and all VT episodes  .\u201dThe authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. The original publication has also been updated."}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors\u2019 attention by a concerned reader that one of the data panels shown for the cell invasion assays in Fig. 2D was strikingly similar to another data panel that had appeared in different form in another article by different authors. Owing to the fact that the contentious data in the above article had already been published elsewhere prior to its submission to"}
{"text": "The authors regret that the figures throughout the article were incorrectly referenced. The correct references for each figure are described in The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "B. Eng., 2018, 154, 99\u2013107, https://doi.org/10.1016/j.compositesb.2018.08.001.The authors regret that part of Fig. 1 and the Graphical Abstract were reproduced from a published article without appropriate acknowledgment. The reference to be included is Gir\u00e3o et al. have granted permission for part of their Fig. 1 to be used in \u201cPreparation and characterization of a novel drug-loaded Bi-layer scaffold for cartilage regeneration\u201d.Gir\u00e3o The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "The authors regret the Author Disclosure information was missing from the above-mentioned published article. The information is now reproduced below. The authors would like to apologise for any inconvenience caused.No conflict declared."}
{"text": "The authors regret that the name of one of the authors (Naeem F. Qusty) was shown incorrectly in the original article. In addition, the author contributions were incorrectly given. The corrected author list and contributions are as shown here.A. S. (Abdu Saeed): conceptualization, software, data curation, writing \u2013 review & editing. S. Y. Q. (Safaa Y. Qusti): conceptualization, supervision, writing \u2013 review & editing. R. H. A. (Rawan Hamdan Almarwani): methodology, investigation, experiment measurements, writing \u2013 original draft. E. J. J. (Ebtihaj J. Jambi): validation, writing \u2013 review & editing. E. M. A. (Eida M. Alshammari): validation, writing \u2013 review & editing. N. F. Q (Naeem F. Qusty): validation, writing \u2013 review & editing. M. J. B. : conceptualization, supervision, writing \u2013 review & editing.\u00a0The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Maximilian Klein et al., CrystEngComm, 2015, 17, 2070\u20132073, https://doi.org/10.1039/C4CE02347A.Correction for \u2018A 3-dimensional {4 The correct Schl\u00e4fli symbol is {42\u00b784}\u00b7{42\u00b784} corresponding to a pts net.The authors regret an error in the assignment of the net descriptor. In the original paper, the Schl\u00e4fli symbol was given as {4lvt should appear as pts, and the assignment of {42\u00b784} is corrected to {42\u00b784}\u00b7{42\u00b784}.Throughout the paper, including the title, The authors apologise for this error and for any inconvenience caused to readers.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "The authors regret that the following Patient Consent Statement was missing from the above article:Patient ConsentAll patients were informed that data can be used for research and QA purposes, and possibly used in scientific publications (anonymized).The authors would like to apologise for any inconvenience caused."}
{"text": "The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Computational and Mathematical Methods in Medicine has retracted the article titled \u201cAnalysis of Anesthesia Effect of Dexmedetomidine in Clinical Operation of Replantation of Severed Finger\u201d [ Finger\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifiThe authors do not agree to the retraction."}
{"text": "The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Erratum zu:Herzschr Elektrophys 202210.1007/s00399-022-00855-xIn der Originalversion des Beitrags stand der Hinweis zu Teil\u00a02 im Untertitel. Dieser Hinweis wurde nun in den Haupttitel eingef\u00fcgt.Der Originalbeitrag wurde korrigiert."}
{"text": "In Evolutionary Applications 15:12, for the article by Lamarins et al.\u00a0 entitledAll authors contributed equally to the conceptualization of the ideas developed in this study, and to the initial review and synthesis of the literature. Hence, the first five authors  should be considered as co\u2010first authors, while the five last authors  should be considered as co\u2010senior authors. The doctoral students  wrote the first draft of this manuscript and designed the figures. A smaller group  took on the second literature survey required by the reviewers. All authors reviewed, edited and approved the final manuscript. J.L and C.P were involved in the acquisition of funds."}
{"text": "Correction to: Behav Res10.3758/s13428-021-01759-3The authors report changes to Fig, 1 of this paper (below). ORCIDs and affiliations have also been updated."}
{"text": "The authors regret that the image used for Fig. 1e in the original manuscript was from an incorrect sample.The correct image is given here.The authors state that the findings and overall conclusions presented in the original article are unaffected by this change.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "The symbols following their names originally appeared as follows:a Ding Ren,a,b,1Hui Liu,They now appear as follows:a,\u2021 Ding Ren,a,b,\u2021Hui Liu,Xiaojin Luo and Pingli Lu are the authors for correspondence. The symbols following their names originally appeared as follows:a,e,1 and Pingli Lua,b,1Xiaojin Luo,They now appear as follows:a,e,* and Pingli Lua,b,*Xiaojin Luo1 to *. The superscript appearing before the line \u201cThese authors contributed equally to this work\u201d has been changed from 1 to \u2021.Additionally, the superscript appearing before the addresses for correspondence has been changed from We apologize to the authors for the errors above."}
{"text": "DOI: 10.1039/C6RA12414C.Correction for \u2018Facile preparation of novel quaternary g-C The authors regret that incorrect images were used in Fig. 2i (page 106575) and Fig. 3b (page 106576). The correct images are shown below.3N4/Fe3O4/AgI/Bi2S3 (30%) nanocomposite.Fig. 2i. EDX mapping of the g-C3N4/Fe3O4/AgI/Bi2S3 (30%) nanocomposite.Fig. 3b TEM image of the g-CThe Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Prod. Rep., 2022, 39, 1438\u20131464, https://doi.org/10.1039/D2NP00003B.Correction for \u2018Fruity, sticky, stinky, spicy, bitter, addictive, and deadly: evolutionary signatures of metabolic complexity in the Solanaceae\u2019 by Paul D. Fiesel  The authors regret that the acylation positions on the sugar backbone of the acylsugars depicted in The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Retraction Note: J Ovarian Res 9, 57 (2016)10.1186/s13048-016-0266-3The Editor-in-Chief has retracted this article. After publication, the authors informed the journal that the associated data and documents were lost to technical issues. Therefore, the authors are no longer able to provide the raw data or evidence of ethics approval and patient consent.None of the authors have responded to any correspondence from the editor or publisher about this retraction notice."}
{"text": "The authors of \u201cRevision Total Knee Arthroplasty Using Robotic Arm Technology\u201d  would liWe have reviewed the article by Steelman et\u00a0al  and openMatthew Bullock is a paid presenter for Smith & Nephew; is an unpaid consultant for Osso VR; has stock in Stryker; received educational support from Stryker, Smith & Nephew, Depuy, and Zimmer/Biomet; is a part of Editorial Board Arthroplasty Today; is a board member of AAKHS Patient Education Committee and West Virginia Orthopaedic Society Education Committee. The other authors declare no potential conflicts of interest.https://doi.org/10.1016/j.artd.2022.101091.For full disclosure statements refer to"}
{"text": "The authors regret that in the above-stated article, the number and percentage of people taking vitamin D in the placebo group was incorrectly listed as \u201c3 (80.5)\u201d in Table\u00a01. The correct number and percentage are \u201c33 (80.5).\u201dThe authors would like to apologize for any inconvenience caused."}
{"text": "Journal of Healthcare Engineering has retracted the article titled \u201cClinical Efficacy and Safety of Percutaneous Spinal Endoscopy versus Traditional Open Surgery for Lumbar Disc Herniation: Systematic Review and Meta-Analysis\u201d [nalysis\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifiThe authors do not agree to the retraction."}
{"text": "Computational Intelligence and Neuroscience has retracted the article titled \u201cNomogram to Predict Overall and Cancer-Specific Survival in Patients with Synovial Sarcoma in the Extremities: A Population-Based Study\u201d [d Study\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifiThe authors do not agree with the retraction."}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors\u2019 attention by a concerned reader that certain of the data shown for the cell invasion assays in Figs. 4D and 5D were strikingly similar to data appearing in different form in other articles by different authors. Owing to the fact that the contentious data in the above article had already been published elsewhere, or were already under consideration for publication, prior to its submission to"}
{"text": "Journal of Healthcare Engineering has retracted the article titled \u201cApplication of Rapid Rehabilitation Nursing in Thoracic Surgery Nursing\u201d [Nursing\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifi"}
{"text": "The authors regret that that the title of their published work requires an update. While we utilized the term \u201cplacebo-controlled\u201d in our original title and methods, we believe that \u201cactive-controlled\u201d trial more accurately describes the design of our study. Subjects randomized to the control arm received a fractionated dose of intradermal IPV without the mucosal adjuvant (dmLT) under study, making their designation as a placebo arm inappropriate. This is an important distinction which we feel significantly impacts both interpretation of the resultant data and any conclusions of the study. We apologize that this was not noticed prior to publication and the revised title is now reproduced above.The authors would like to apologise for any inconvenience caused."}
{"text": "This article has been retracted: Oncotarget has completed its investigation of this paper. We found that Figures 2C, 2E, 6B, and 6F contain similarities with data appearing in other articles by different authors. The data had already been published elsewhere, or were already under consideration for publication prior to submission to Oncotarget. On June 15, 2022 Oncotarget received a signed letter asking to retract the paper because certain experiments, including cell colony formation and in vivo assay, were unable to be reproduced. Oncotarget has notified the affiliated institution regarding this retraction.2825-2834. https://doi.org/10.18632/oncotarget.13747Original article: Oncotarget. 2017; 8:2825\u20132834."}
{"text": "This abstract has been withdrawn."}
{"text": "Correction to: Eur J Nucl Med Mol Imaging (2022) 49:632\u2013651https://doi.org/10.1007/s00259-021-05603-wThe authors regret a typo in the units assessing hyperglycaemia, which should be defined as > 8.9 mmol/L, and not as erroneously mentioned in the published version as > 8.9 nmol/L."}
{"text": "Table"}
{"text": "In this article, the authors assess the clinical presentation of patients with urethral cuff erosion after the implant of an Artificial Urinary Sphincter (AUS) and also attempt to establish risk factors in this patient population   . As wel"}
{"text": "In"}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors\u2019 attention by a concerned reader that certain of the data shown for the cell migration and invasion assays in Figs. 2C and 4C were strikingly similar to data appearing in different form in other articles by different authors. Owing to the fact that the contentious data in the above article had already been published elsewhere, or were already under consideration for publication, prior to its submission to"}
{"text": "The Editors-in-Chief would like to alert readers that concerns have been raised regarding the data in this article . SpecifiNone of the authors have responded to any correspondence from the editor or publisher about this Editorial Expression of Concern."}
{"text": "The revised version of"}
{"text": "In the original publication , there wThe correct title appears below.n) with records of ARD-T, and lung and ovarian cancer in the 29 municipalities (H-ASB) and for all Brazilian municipalities, 2000\u20132017.Table 1. Number of deaths (In the original publication , there wThe authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. The original publication has also been updated."}
{"text": "In the version of this article initially published, there were errors resulting from merged authors\u2019 names. The following sentences highlight the errors and the corrected details:1 Abayomi Fadeyi, 2 Adekunle Olatayo Adeoti, 3 Muhammed Akanbi Nurudeen Adeboye, 4 Joseph Abioye Awosanya, 5 Ibironke Omowumi Oluwadiya, 6* Kehinde Sunday Oluwadiya.Should read:1Fadeyi Abayomi, 2 Adeoti Adekunle Olatayo, 3Adeboye Muhammed Akanbi Nurudeen, 4Awosanya Joseph Abioye, 5Oluwadiya Ibironke Omowumi, 6*Oluwadiya Kehinde Sunday."}
{"text": "In the initially published version of our article, we recently realized that there are errors in several figures and Table 2 due to misplace of images and data. The corrections are provided below.Finally, the author list in the paper should be updated as above in this erratum.The correction does not change the overall conclusions of this paper. We apologize for the error and for any inconvenience that may cause to the readers and the editors of this journal."}
{"text": "To the Editors:We read with interest the recent paper in your journal by Holzmann\u2010Littig and colleagues entitled \u201cEstimating serum\u2010ionized magnesium concentration in hemodialysis patients\u201d.ion is methodologically challenging and cost\u2010intensive in clinical practice.\u201d.In the introduction, the authors state that \u201c\u2026accurate measurement of MgThe authors are to be commended for the work involved in developing and validating this formula. The authors state that \u201cAn equation containing three variables performed well both in terms of accuracy to estimate the ionized value and to predict normomagnesemia.\u201d However, this formula has only been found to be 84% accurate in the external validation cohort, with an area under the curve (AUC) of only 0.78 for determining normomagnesemia.Both authors are employees of Nova Biomedical."}
{"text": "Furthermore, they apologise to the readership for any inconvenience caused.The authors have re-examined their data and realized that"}
{"text": "The Margret M. and Paul B. Baltes Award Lecture will feature an address by the 2021 Baltes Award recipient, Laura B. Zahodne, PhD, of the University of Michigan. This session will also include the presentation of the 2022 Margret M. and Paul B. Baltes Award to recipient Eric S. Kim, PhD, of the University of British Columbia. The Margret M. and Paul B. Baltes Foundation Award in Behavioral and Social Gerontology recognizes outstanding early-career contributions in behavioral and social gerontology. The award is generously funded by the Margret M. and Paul B. Baltes Foundation."}
{"text": "Communications Biology 10.1038/s42003-021-02787-7, published online 19 November 2021.Correction to: An oversight was committed in neglecting to include several Malian co-authors who conducted the clinical study and provided samples for the study in the list of authors. This has now been corrected in the PDF and HTML versions of the Article.Corrected list of authors and affiliations:1, Justin Y.A. Doritchamou1, Bergeline C. Nguemwo Tentokam1, Robert D. Morrison1, Matthew V. Cowles1, Martin Burkhardt1, Rui Ma1, Almahamoudou Mahamar2, Oumar Attaher2, Bacary S. Diarra2, Moussa Traore2, Alassane Dicko2, Niraj H. Tolia1, Michal Fried1, Patrick E. Duffy1Jonathan P. Renn1 Laboratory of Malaria Immunology and Vaccinology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.2 Malaria Research and Training Center, University of Sciences, Techniques, and Technologies of Bamako, Bamako, Mali."}
{"text": "Sci., 2022, https://doi.org/10.1039/d2sc04846a.Correction for \u2018ThC The authors regret that incorrect details were given for ref. 53 and 54 in the original article. The correct version of ref. 53 and 54 is given below.Phys. Rev. Lett., 1996, 77, 3865\u20133868.53. J. P. Perdew, K. Burke and M. Ernzerhof, Phys. Rev. Lett., 1998, 80, 891.54. J. P. Perdew, K. Burke and M. Ernzerhof, The authors also regret that there was an error in the sentence in lines 12\u201313 in the left column on page 5 of the original article. The text originally read, \u201cThe carbon lone pairs are even stronger donating, with 13% weight at thorium.\u201d This sentence should read, \u201cThe carbon lone pairs are even stronger donating, with 14% weight at thorium.\u201dThe Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Paleomagnetism measures apparent polar wander (APW), continental motion relative to the magnetic pole, where APW = plate motion + true polar wander (TPW).  Although the authors rule in favor of plate motion, by their own admission: \u201cThat said, it is technically possible to ascribe all observed motions to two successive TPW events.\u201d If the APW is instead due to TPW, then the Paleoarchean data have no bearing on ancient tectonics.Early plate tectonics is hotly debated, and paleomagnetic data can provide critical tests . BrennerTheir argument against TPW is that the two APW segments identified have orientations that differ by 48\u00b0 to 90\u00b0, and \u201cdue to persistence in the geoid shape,\u201d this is unlikely for TPW. Much of this difference derives from the structural rotation of the younger two poles from the same syncline relative to the rest of Pilbara. But the authors consider scenarios between 0 and 70\u00b0 rotation because its magnitude is uncertain and may be zero. Without structural rotation, then the three poles exhibit an essentially continuous direction of polar motion, thus invalidating the empirical basis of their argument against TPW A.Assuming their preferred structural rotation of the young poles is correct, the two APW events are nearly orthogonal B. A signAPW speed is used to bolster their tectonic interpretation . The Pal"}
{"text": "Following publication, concerns were raised regarding the integrity of the images in the published figures. The authors failed to provide a satisfactory explanation during the investigation, which was conducted in accordance with Frontiers\u2019 policies.Given the concerns, the editors no longer have confidence in the findings presented in the article.During correspondence, the authors did not respond to the question of whether they agree or disagree to the retraction.This retraction was approved by the Chief Editors of Frontiers in Physiology and the Chief Executive Editor of Frontiers."}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors\u2019 attention by a concerned reader that certain of the cell migration assay data shown in Fig. 2C were strikingly similar to data that had appeared in different form in another article by different authors. Owing to the fact that the contentious data in the above article had already been published elsewhere prior to its submission to"}
{"text": "Scientific Data 10.1038/s41597-022-01292-8, published online 29 April 2022Correction to: Figure 2 of the paper was incorrect in the original version, with the labels for \u201cNon-zero electric dipole\u201d and \u201cZero electric dipole\u201d switched around. This has been corrected in the HTML and pdf versions of the paper, which now indicates that \u201cNon-zero electric dipole moment\u201d sits within the Design principles for Rashba SS box on the right side of the figure, and \u201cZero electric dipole\u201d sits within the Design Principles for Dresselhaus SS on the left, as the authors originally intended."}
{"text": "Journal of Healthcare Engineering has retracted the article titled \u201cApplication of Deep Learning Technology in Glioma\u201d [ Glioma\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifi"}
{"text": "Erratum zu:Herzschr Elektrophys 202210.1007/s00399-022-00917-0In diesem Artikel wurde Abb.\u00a0Der Originalbeitrag wurde korrigiert."}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of the above paper, a concerned reader drew to the Editors' attention that the Transwell cell migration and invasion assay data shown in Fig. 3C appeared to overlap in a pair of the data panels within this figure; in addition, data that were strikingly similar to those included in this figure had already appeared in previously published papers written by different authors at different institutes. Moreover, there was an unexpected level of similarity regarding the control \u03b2-actin bands shown in the three western blot experiments in Fig. 4B, even though these experiments related to three different cell lines. Having considered the issues identified, the Editor of"}
{"text": "The updated affiliation information can be seen in the affiliation part of this correction.\u201cIFPDP-31-22\u201d to \u201cMohammad Zubair Alam\u201d was not included. The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. The original publication has also been updated.In the original publication , the funThe corrected Funding and Acknowledgment appear below:"}
{"text": "Journal of Healthcare Engineering has retracted the article titled \u201cDiscipline Construction and Development of Medical Universities in Complex Environment under Digital Technology and Structural Equation Model\u201d [n Model\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifiThe authors do not agree to the retraction."}
{"text": "The authors wish to make the following changes to their paper .F = 169.3, p < 0.001; Sham vs. HSI + Scramble, p < 0.001; Sham vs. HSI + Agomir-let-7i, p = 0.803; HSI + Scramble vs. HSI + Agomir-let-7i, p < 0.001) .\u2019 has been amended to read \u2018Next, we examined whether there are any expression changes in STING in agomir-let-7i-treated uninjured brains. Consistent with our expectations, a reduced STING mRNA expression level was observed in the hippocampi of agomir-let-7i-treated mice compared to scramble-treated mice F = 169.3, p < 0.001; Vehicle vs. Agomir-let-7i, p < 0.001; Vehicle vs. Scramble, p = 0.803; Scramble vs. Agomir-let-7i, p < 0.001) \u2019.In the text of this article initially published (PDF version), there were typing errors in the last paragraph of Page 10. The text originally reading \u2018Next, we examined whether there are any expression changes in STING in agomir-let-7i-treated HSI brains. Consistent with our expectations, a reduced STING mRNA expression level was observed in the hippocampi of agomir-let-7i-treated HSI mice compared to scramble-treated HSI mice (Figures 3, 4 and 6 should be replaced. In the original publication, there were labeling errors in Figures 3 and 6. In Figure 3B, the labels \u2018HIS + Scramble\u2019 and \u2018HIS + Agomir-let-7i\u2019 were inadvertently swapped. The corrected In Figure 4A of the initially published article, the separate image of TUNEL staining in the HIS + Agomir-let-7i group was erroneously flipped horizontally. The error does not affect the conclusions reported in the paper. The corrected x-axis label, now reading \u2018Vehicle\u2019 and \u2018Scramble\u2019, initially appeared as \u2018\u2018Control\u2019 and \u2018Agomir-NC\u2019. In Figure 6E, the x-axis label, now reading \u2018HIS + Scramble\u2019 and \u2018HIS + Agomir-let-7i\u2019, initially appeared as \u2018Stroke + Scramble\u2019 and \u2018Stroke + Agomir-let-7i\u2019. In the Figure 6D caption, the text originally reading \u2018the hippocampi of sham, scramble-treated and agomir-let-7i-treated HSI mice\u2019 has been amended to read \u2018the hippocampi of Vehicle-, scramble- and agomir-let-7i-treated uninjured mice\u2019. The corrected In Figure 6D, the The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "The authors are grateful to the interested reader for drawing this matter to their attention, and also apologize to the readership for any inconvenience caused.The authors have consulted their original data, and realize that errors were made with the semiquantification of the data; therefore, a revised version of"}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors' attention by a concerned reader that various panels showing data from flow cytometric experiments in Figs. 2D and 5D were strikingly similar to data appearing in different form in other articles by different authors. Owing to the fact that the contentious data in the above article were already under consideration for publication, or had already been published, elsewhere when it was submitted to"}
{"text": "Retraction to: Nature Communications 10.1038/s41467-020-17310-5, published online 15 July 2020The\ufeff data in Fig. 3c did not originate from three biological replicates as claimed in the legend;In Figs. 3c and 5f, multiple lanes could not be matched back to the original raw data in the laboratory records;The GAPDH bands in Figs. 3c, 5f and 6e could not be matched with raw data;The LC-3B image in Fig. 5f was duplicated and rotated 180 degrees in Fig. 6e to represent p-AMPK (T172);In Fig. 7d, the 4X and 10X images did not originate from the same samples;In Fig. 7d, the 10X images of Mtb H37Rv + Ornithine and Mtb H37Rv + Imidazole contain overlap.The Editor has retracted this Article at the authors\u2019 request. Following concerns from a reader, the authors initiated an internal investigation. After comparing the laboratory record and the figures, it was concluded that:Further data similarities have been identified in Figs. 2j and S1, as well as within Figs. S5, S10, S11 and S16. In light of these issues, the authors have requested to retract this Article.Ramya Sivangala Thandi has not responded to any correspondence from the editor or publisher about this retraction. All other authors agree to this retraction."}
{"text": "In addition, the spectra in the original figure do not match with the relevant discussion of 3N4, CaFe2O4 and CaFe2O4/g-C3N4/CNT composite. The correct image for The authors regret that mistakes were made during the preparation of The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "The stu"}
{"text": "Journal of Healthcare Engineering has retracted the article titled \u201cDiscussion on Health Service System of Mobile Medical Institutions Based on Internet of Things and Cloud Computing\u201d [mputing\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifi"}
{"text": "DOI: 10.1039/D1RA04855D.Correction for \u2018An indenocarbazole-based host material for solution processable green phosphorescent organic light emitting diodes\u2019 by Eun Young Park  The authors regret that an incorrect version of The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Correction: Mol Cancer 14, 10 (2015)https://doi.org/10.1186/s12943-014-0274-0; Published: 27 January 2015The Editor-in-Chief is issuing an editorial expression of concern to alert readers that this article shows signs of irregularities within the 1st and 4th image of VEGF in Figure 6G after this was highlighted by a reader. The Editor-in-Chief advises the readers to interpret the data with due caution. All authors agree to this Editorial Expression of Concern."}
{"text": "Journal of Healthcare Engineering has retracted the article titled \u201cClinical Study on the Relationship between the SNP rs8192675 (C/C) Site of SLC2A2 Gene and the Hypoglycemic Effect of Metformin in Type 2 Diabetes\u201d [Following an investigation conducted by the Hindawi Research Integrity team , signifiThe authors do not agree to the retraction."}
{"text": "Abstract citation ID ckac131.313 has been removed"}
{"text": "At the request of the authors, we report that in the paper published in the Sao Paulo Medical Journal, volume 137, issue number 6, DOI: 10.1590/1516-3180.2018.0370160919, page 550:Where it read:IPhD. Doctoral Student, Faculty of Industrial Management, Universiti Malaysia Pahang, Kuantan, Malaysia\u201d\u201cIt should read:\u201cPhD. Assistant Professor, Electrical Engineering Department, Institute of Business Management (IoBM), Karachi, Pakistan\u201d"}
{"text": "Furthermore, they apologize to the readership for any inconvenience caused.The revised version of"}
{"text": "In view of the fact some of these data had already apparently been published previously, the Editor of Oncology Reports has decided that this paper should be retracted from the Journal. The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors\u2019 attention by a concerned reader that certain of the Transwell invasion assay data panels shown in Fig. 3A were strikingly similar to data appearing in different form in other articles written by different authors, but which had already been published elsewhere prior to this paper's submission to"}
{"text": "Escherichia coli by random mutagenesis for improved lycopene\u2019 by Hailin Chen et al., RSC Adv., 2018, 8, 15021\u201315028.Correction for \u2018Directed evolution of mevalonate kinase in  Microbial Cell Factories,1 which should have been cited in this RSC Advances paper.The authors wish to draw the readers\u2019 attention to their closely related paper, published in RSC Advances paper and RSC Advances article.The authors regret that there is unattributed overlap in text between this RSC Advances paper, a directed evolution strategy was used to optimize the activity of MK to enhance the tolerance for farnesyldiphosphate (FPP) and geranylgeranyldiphosphate (GGPP), to enhance the affinity of mevalonate and MK, and to improve lycopene production. The catalytic mechanisms of both enzymes are very different; however improving their activities can improve lycopene production.Two different rate-limiting enzymes in the lycopene synthetic pathway were studied using the same methods, mevalonate kinase (MK) in this paper and isopentenyl diphosphate isomerase (IDI) in The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors\u2019 attention by a concerned reader that the data in the centre panel shown for the cell invasion assays in Fig. 2C were strikingly similar to data appearing in different form in other articles by different authors. Owing to the fact that the contentious data in the above article had already been published elsewhere prior to its submission to"}
{"text": "National Science Review, Volume 10, Issue 1, 2023, https://doi.org/10.1093/nsr/nwac256). In the original published version of this manuscript, only Xiaotie Deng is listed as the corresponding author. The published manuscript has now been corrected to also include Ningyuan Li and Yaodong Yang as corresponding authors.Xiaotie Deng, Ningyuan Li and Yaodong Yang are corresponding authors of \u2018On the complexity of computing Markov perfect equilibrium in general-sum stochastic games\u2019 ("}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a satisfactory reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors\u2019 attention by a concerned reader that certain of the cell migration and invasion assay data shown in Figs. 2C and 5C were strikingly similar to data appearing in different form in other articles by different authors. Owing to the fact that the contentious data in the above article had already been published elsewhere, or were already under consideration for publication, prior to its submission to"}
{"text": "They also wish to apologize to the readership of the Journal for any inconvenience caused.The revised version of"}
{"text": "The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper hence has issued an Expression of Concern to notify readers whilst the Editorial Office investigates. A duplicated, modified region has been identified between the miR-145 mimic and siHOXA1 panels of Figure 4C, as well as concerns raised regarding the western blots in Figures 6 and 7."}
{"text": "For this paper the corresponding author should be as indicated above. Additionally in the Acknowledgements section the following should have been included: We acknowledge support by Deutsche Forschungsgemeinschaft and Open Access Publishing Fund of Karlsruhe Institute of Technology.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Journal of Oncology has retracted the article titled \u201cIdentification of the Novel Methylated Genes' Signature to Predict Prognosis in INRG High-Risk Neuroblastomas\u201d [astomas\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifiThe authors agree to the retraction."}
{"text": "Therefore, for the academic rigor of the paper, we modify Equation (8) to the correct form. The corrected Equation (8) appears below.There was an error in the original publication . In the The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. The original publication has also been updated."}
{"text": "Babesia microti is not transmitted transovarially. Babesia crassa-like agent has been found in I. persulcatus ticks in China rather than I. scapularis ticks. Several minor spelling and capitalization errors also were identified. There were two factual errors in the original publication of our manuscript  entitledThe authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "Nucleic Acids Research, Volume 29, Issue 17, 1 September 2001, Pages 3539\u20133545, https://doi.org/10.1093/nar/29.17.3539In November 2021, a reader raised concerns about potential image manipulation in Figure 3A. The authors are unable to provide the original data generated more than 20 years ago. The editors and the authors\u2019 institution have since examined the image, and the results were inconclusive. The editors advise readers to consider this image with care.Julian E. Sale and Barry L. StoddardSenior Executive Editors"}
{"text": "Missing FundingThe authors wish to make the following correction to this paper .Missingthe supporter and funder, Italian Ministry of Health\u2014Ricerca Corrente 2022, was not included. The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated.In the original publication,"}
{"text": "The authors would like to update the affiliations for Umair Umer and Syed Kazim Usman in the published publication . In addiThe authors state that the scientific conclusions are unaffected. The original publication has also been updated."}
{"text": "Journal of Healthcare Engineering has retracted the article titled \u201cThe Application of DOMS Mechanism and Prevention in Physical Education and Training\u201d [raining\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifiThe authors do not agree to the retraction."}
{"text": "Gurz\u0119da  The authors regret that the incorrect project number as financial support was included in the original article. The correct project number is 2015/17/B/ST8/00371.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "The authors regret the error in Fig."}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors attention by a concerned reader that the western blotting assay data shown in Figs. 5B, 5E, 6C and 7A were strikingly similar to data appearing in different form in other articles by different authors. Owing to the fact that the contentious data in the above article had already been published elsewhere, or were already under consideration for publication, prior to its submission to"}
{"text": "Correction to: Naunyn-Schmiedeberg's Archives of Pharmacology (2022) 395:867\u201388510.1007/s00210-022-02250-2We regret to inform readers that our paper  had mistakenly stated that tralokinumab \u201cis administered via weekly subcutaneous injection\u201d (p. 873). This should have read that tralokinumab \u201cis administered as a loading dose, followed by subcutaneous injection every other week\u201d. We apologize for any inconvenience this mistake may have caused."}
{"text": "Trianthema portulacastrum Linn. on dermal wounds via removal of oxidative stress and inflammation\u2019 by Ekta Yadav et al., RSC Adv., 2018, 8, 21621\u201321635, https://doi.org/10.1039/C8RA03500H.Expression of concern for \u2018Ameliorative effect of biofabricated ZnO nanoparticles of  RSC Advances is publishing this expression of concern in order to alert our readers that we are presently unsure of the reliability of the data reported in Fig. 3 of the article. A number of the wound healing images in Fig. 3 have been duplicated either within the figure, or in two of the authors' publications in Biomedicine & Pharmacotherapy.1,2The authors have provided a replacement figure for consideration and say that the new data does not affect the conclusions of the paper. The Royal Society of Chemistry has asked the affiliated institution to investigate this matter and establish whether the replacement images provided by the authors provide an accurate representation of the experiments that were conducted, and confirm the integrity and reliability of the new data provided. An expression of concern will continue to be associated with this manuscript until we receive information from the institution on this matter.Laura Fisherth January 202324RSC AdvancesExecutive Editor,"}
{"text": "This article has been retracted: Aging has completed its investigation of this paper. We found overlap between some transwell assay images used for Figures 3G and 6E and data previously published by different authors. The authors confirmed the overlap and also raised a concern that the statistical methods used for some analyses were inappropriate. As a result, all of the listed authors agreed that the article should be retracted.The Administration of the First Affiliated Hospital of Xinxiang Medical University was notified about the retraction by Aging Journal. The Ethics Committee of The First Affiliated Hospital of Xinxiang Medical University agreed that this paper should be retracted because the errors in the statistical methods led to an insufficiently rigorous analysis of the results and because of the improper use of several pictures included in this manuscript. The authors deeply regret any inconvenience this publication has caused for the scientific community."}
{"text": "Following the publication of this article , concern\u25cb Fig 4 left \u03b2-actin panel lanes 3 and 5, Fig 4 right \u03b2-actin panel lanes 3 and 5, and Fig 4 bottom \u03b2-actin panel lanes 1, 2, and 3.\u25cb Fig 4 left \u03b2-actin panel lane 4, and Fig 4 right \u03b2-actin panel lanes 2 and 4.\u25cb Fig 8 ACAT-2 panel lanes 2 and 4.\u25cb Fig 9 \u03b2-actin panel lanes 1 and 5\u25cb Fig 13A RXR\u03b1 panel lanes 2 and 5.\u25cb Figs 13A, 13B, 13C, 13D, 14B, and 14D GAPDH panels\u25cb Fig 13B RXR\u03b2 panel lanes 1 and 4.\u25cb Fig 13C LXR\u03b1 panel lane 5 and Fig 13D LXR\u03b2 panel lane 1.\u25cb Fig 14A PPAR\u03b1 lanes 1\u20132 and Fig 14C PPAR\u03b3 lanes 4\u20135.\u25cb Fig 14A and Fig 14C GAPDH panels.\u25cb Fig 14B PPAR\u03b2 panel lanes 2 and 5.\u25cb Fig 14D SREBP2 panel lanes 1 and 4.The following results appear similar:\u25cb Fig 2 NPY1R panel, between all lanes\u25cb Fig 4 NPC1L1 panel, between lanes 2\u20133 and lanes 3\u20134.\u25cb Fig 4 CD36 panel, between lanes 3\u20134.\u25cb Fig 12 MTP panel, between lanes 3\u20134.\u25cb Fig 13C LXR\u03b1 panel, between lanes 4\u20135.\u25cb Fig 14C PPAR\u03b3 panel, between lanes 2\u20133.\u25cb Fig 14D SREBP2 panel, between lanes 2\u20133.When levels are adjusted to visualize background, there appear to be vertical irregularities suggestive of splice lines in:The corresponding author states that the similarity between proteins is due to the stripping and re-probing of the same blot, and clarifies that some blots were spliced to remove extra lanes and/or duplicate or triplicate samples from the panel. The underlying data for the figures or concern are no longer available.PLOS ONE Editors retract this article.In light of the concerns affecting multiple figure panels that question the integrity of these data, the EG, CG and ED either did not respond directly or could not be reached. EL did not agree with the retraction."}
{"text": "The revised version of Experimental and Therapeutic Medicine for granting them the opportunity to publish this; furthermore, they apologize to the readership for any inconvenience caused.Note that this error did not have a major impact on either the overall results or on the conclusions reported in this study. The authors regret the errors that were made during the compilation of the data into"}
{"text": "Bioscience Reports at the request of the Editor-in-Chief and the Editorial Board following receipt of a notification from a reader, alerting the Editorial Board to multiple similarities between the western blots of this manuscript and those of other articles. The GAPDH bands from Figure 3F are similar to those found in Fig. 6A A549/GAPDH from Wang et al. 2019 (doi: 10.1042/BSR20182433) and Fig. 4C AMC-HN-8/GAPDH from Li et al. 2019 (doi: 10.1042/BSR20181882). The authors have been contacted with regards to the retraction and have not responded to the Journal's queries or the concerns raised. Given the extent of the issues raised, the Editorial Board stand by the decision to retract the article.This article is being retracted from"}
{"text": "Scientific Reports 10.1038/s41598-020-69192-8, published online 22 July 2020Retraction of: The Editors have retracted this Article. Following publication, concerns were raised about the rationale for the approach presented and the underlying reasoning. A post-publication review of the authors' mathematical arguments revealed a lack of clarity in the terms presented and inferences that are not adequately justified. The Editors therefore no longer have confidence in the conclusions presented.Muhammad Aslam and Khushnoor Khan do not agree to this retraction. Abdulmohsen Al Shareef did not respond to correspondence relating to this retraction."}
{"text": "The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an Expression of Concern to notify readers whilst the Editorial Office investigates. Duplications have been identified across multiple papers with no common authors. Figure panel 3b appears to be the same as Figure 3B of the article \u2018Long noncoding RNA 00460 (LINC00460) promotes glioma progression by negatively regulating miR-320a\u2019 (DOI: 10.1002/jcb.28232) and as Figure 3D  of the article \u2018STAT3-mediated upregulation of lncRNA HOXD-AS1 as a ceRNA facilitates liver cancer metastasis by regulating SOX4\u2019 (DOI: 10.1186/s12943-017-0680-1). The authors have been contacted with regards to these concerns."}
{"text": "A final reflection on the importance of evaluation aspects will be proposed at the end of the workshop."}
{"text": "Journal of Healthcare Engineering has retracted the article titled \u201cThe Clinical Effect of High-Flow Oxygen Therapy through the Nose on Patients with Acute Left Heart Failure and Hypoxemia\u201d [poxemia\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifiThe authors disagree to the retraction."}
{"text": "Enterobacter faecalis MSI12 and its effect on the disruption of Candida albicans biofilm\u2019 by G. Seghal Kiran et al., RSC Adv., 2015, 5, 71573\u201371585, DOI: 10.1039/C5RA10302A.Correction for \u2018Characterization of an exopolysaccharide from probiont  The authors regret that incorrect versions of Accordingly, the experimental methods followed in the phase contrast microscopy and large-size images of The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "The authors wish to make a change to the author names  for this paper . Daskala1,*, Pierre-Christian Violet 2, Gustavo Vasquez 1, Katherine Belden 1, Michael Foster 3, Bret Mullin 3, Devon Magee 3, Isabelle Mikell 4, Lokesh Shah 4, Victoria Powers 4, Brian Curcio 5, Daniel Monti 6 and Mark Levine 2,*Dagan Coppock Author Contributions: P.-C.V., D.M. (Daniel Monti) and M.L. conceived the study; D.C., D.M. (Daniel Monti), M.L. and M.F. developed the trial methodology; D.C., G.V., K.B. and B.M. reviewed and enrolled subjects; D.C., D.M. (Daniel Monti), G.V. and K.B. provided clinical oversight and monitored safety; B.M., D.M. (Devon Magee), I.M., L.S. and V.P. were responsible for preparing and curating data; B.C. and D.C. performed formal analyses; D.C. and M.L. prepared the original manuscript draft; all authors reviewed and edited the manuscript; D.M. (Daniel Monti) acquired funding; D.C., D.M. (Daniel Monti) and M.L. supervised overall efforts. All authors have read and agreed to the published version of the manuscript.The \u201cAuthor Contributions\u201d statement thus should be updated to the following version:The second correction was the inclusion of the words \u201cstudy-related\u201d to the sentence: \u201cThere were no reported deaths in either arm.\u201d This sentence has been changed to now read: \u201cThere were no reported study-related deaths in either arm.\u201dThe authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "Journal of Healthcare Engineering has retracted the article titled \u201cEffect of Protein Nutrition Level on Protein Metabolism during Volleyball Exercise Based on Edge Computing in the Medical System\u201d [ System\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifiThe authors do not agree to the retraction."}
{"text": "Pogostemon cablin Benth) using a microwave air-hydrodistillation method as a new green technique\u2019 by Heri Septya Kusuma et al., RSC Adv., 2017, 7, 1336\u20131347.Expression of concern for \u2018The extraction of essential oils from patchouli leaves ( RSC Advances is publishing this expression of concern in order to alert our readers that we are presently unsure of the reliability of the data reported in the article.Periodica Polytechnica Chemical Engineering, 2017, 61, 82\u201392), which has not been cited in this RSC Advances paper. The reproducibility seen between the GCMS data in these two papers is very unlikely. The authors have been unable to provide raw GCMS data for the measurements presented in the RSC Advances article.The Royal Society of Chemistry has been provided with credible information suggesting that the GCMS results presented in the paper may not be reliable. The majority of the microwave hydrodistillation (MHD) GCMS data presented in Table 5 has been reproduced from a previously published paper by the authors (The Royal Society of Chemistry is currently seeking support from the affiliated institution in order to investigate this matter and establish whether the reported results are reliable. An expression of concern will continue to be associated with this manuscript until we receive information from the institution on this matter.Andrew Shore19th November 2018RSC AdvancesExecutive Editor,"}
{"text": "Lastly, the authors apologize to the readership for any inconvenience these errors may have caused.The corrected versions of"}
{"text": "The authors regret that an incorrect grant number for B. Y. Chen was given in the original manuscript. The correct acknowledgements section is as shown below.The authors gratefully acknowledge the financial support provided by the Ministry of Science and Technology (MOST), Taiwan, under Grant No. MOST 104-2221-E-197-004-MY3 (S. H. Chang), 105-2221-E-002-047-MY3 (J. Z. Chen) and 106-2221-E-197-020-MY3 (B. Y. Chen).The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "In the original publication , a mistaThe authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "Frontiers and Cell Development; due to our inattention, the citation [14] was not reported in the paper in Biology and should be added.In the original publication , there wThe authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "Journal of Oncology has retracted the article titled \u201cTMEM60 Promotes the Proliferation and Migration and Inhibits the Apoptosis of Glioma through Modulating AKT Signaling\u201d [gnaling\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifiThe authors do not agree to the retraction."}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors' attention by a concerned reader that certain of the panels shown for the cell invasion assays in Figs. 2C and 6C were strikingly similar to data appearing in different form in other articles by different authors. Owing to the fact that the contentious data in the above article had were already under consideration for publication prior to its submission to"}
{"text": "In the published article in Additionally, in Fig. S7 (ESI), kidney slice pictures of control and GO groups and lung slice pictures of ssDNA-AgNPs and ssDNA-AgNPs@GO were duplicated. A revised version of the ESI has been published.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "To the editor,We appreciate the editorial comments on our manuscript , 2. UnfoThe authors."}
{"text": "BMJ\u00a02022;379:o2459, doi:10.1136/bmj.o2459) during editing. James Kigera and Siaka Sidib\u00e9 were omitted and as a result the affiliations for many of the authors were also incorrect. The online version has been amended. We introduced errors in the author list of this editorial by Lukoye Atwoli and colleagues ("}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors\u2019 attention by a concerned reader that certain of the cell migration assay data shown in Fig. 2D were strikingly similar to data that had appeared in different form in other articles by different authors. Owing to the fact that the contentious data in the above article had already been published elsewhere, or were already under consideration for publication, prior to its submission to"}
{"text": "The authors have retracted this article. After publication it came to the authors attention that there were issues with the quality of the data used in this study. The authors, therefore, no longer have confidence in the results or conclusions of this study. All authors agree to this retraction."}
{"text": "DOI: 10.1039/D1RA03207K.Correction for \u2018Natural bamboo leaves as dielectric layers for flexible capacitive pressure sensors with adjustable sensitivity and a broad detection range\u2019 by Zhihao Liu  The authors regret that an incorrect image was used for The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "The Editors-in-Chief have retracted this article because there are regions of overlap between Fig.\u00a02A and Fig.\u00a04A. The Editors-in-Chief therefore no longer have confidence in the data presented.Li Chen does not agree to this retraction. None of the other authors has responded to any correspondence from the publisher about this retraction."}
{"text": "Euglossa imperialis between April and June. However, this result is incorrect. After reanalyzing the differences between April and June in the amount of blends, the result is not significant .In the paper published by Arriaga\u2010Osnaya et al.\u00a0, the autThe authors apologize for this oversight."}
{"text": "In the acknowledgements, the contract number (3000033429) was wrongly used instead of the fund number (MAUX1801) for the final funding body, and this last funder should read, Ministry of Business, Innovation and Employment Endeavour Fund of New Zealand (MAUX1801).The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "She completed her treatment (see Figure The authors declare they have no conflicts of interest.The photograph was taken with the patient's informed consent and in accordance with the\u00a0declaration of HelsinkiThe authors received no specific funding for this work.Informed consent was obtained."}
{"text": "After a discussion with allof the authors, we have agreed on thefollowing changes to the original manuscript:The authors andaffiliations have been corrected as presented inthis Addition and Correction.The acknowledgments have beencorrected as follows: The authorsthank Dr. Rachael Simister for the technical assistance of matrixpolysaccharide analyses. The authors are grateful to Prof. Simon J.McQueen-Mason for the support at the Centre for Novel AgriculturalProducts (CNAP), University of York, York, U.K., and the Dixon laboratoryat University of North Texas for support with the lignin compositionalanalyses.The author contributions have been corrected as follows:Rosa AnaMalvar and Rogelio Santiago conceived of the study. Rogelio Santiago,Rosa Ana Malvar, and Ana L\u00f3pez-Malvar participated in the experimentaldesign, carried out the field trials, and participated in sample collection.Ana L\u00f3pez-Malvar carried out biochemical determinations andstatistical analysis. Ana L\u00f3pez-Malvar wrote the draft. JaimeBarros-Rios and Leonardo D. G\u00f3mez assisted in biochemical analysisand Results and Discussion. Xose Carlos Souto contributed to the Resultsand Discussion. All authors read and approved the final manuscript."}
{"text": "Circular RNAs (circRNAs) are a new category of endogenous non\u2010protein coding RNAs (ncRNAs), and show the characteristics of high conservation, stability, and tissue specificity. Due to rapid advances in next\u2010generation sequencing and transcriptome profiling technologies, circRNAs have been widely discovered in many organisms and participated in the development and progress of a variety of diseases. As a type of molecular sponge, circRNAs mainly absorb micro RNAs competitively and interplay with RNA\u2010binding proteins to modulate the splicing as well as transcription of target genes.This review is based on a literature search using the Medline database. Search terms used were \u201ccircular RNAs and leukemia,\u201d \u201ccircRNAs and leukemia,\u201d \u201ccircRNAs and acute lymphoblastic leukemia,\u201d \u201ccircRNAs and chronic lymphoblastic leukemia,\u201d \u201ccircRNAs and acute myeloid leukemia,\u201d \u201ccircRNAs and chronic myeloid leukemia,\u201d and \u201ccircRNAs, biomarker, and hematological system.\u201dCircRNAs have been proven as potential biomarkers and therapeutic targets in a variety of tumors. Recent research has found that circRNAs aberrantly exist in hematological cancers, especially leukemia, and are significantly associated with the incidence, progress, and metastasis of diseases as well as the prognosis of patients.The current work summarizes the latest findings on circRNAs in various types of leukemia, aiming to propose prospective therapies and new drug screening methods for the treatment of leukemia. The current work reviews the latest research on circular RNAs\u00a0in various types of leukemia, aiming to provide promising therapeutic methods and novel drug screening strategies for leukemia. Depending on the extent of differentiation and maturation of leukemia as well as its progressive course, leukemia can be categorized into acute or chronic leukemia.2This review is based on a literature search using the Medline database. Search terms used were \u201ccircular RNAs and leukemia,\u201d \u201ccircRNAs and leukemia,\u201d\u00a0\u201ccircRNAs and acute lymphoblastic leukemia,\u201d\u00a0\u201ccircRNAs and chronic lymphoblastic leukemia,\u201d\u00a0\u201ccircRNAs and acute myeloid leukemia,\u201d \u201ccircRNAs and chronic myeloid leukemia,\u201d and \u201ccircRNAs, biomarker, and hematological system.\u201d3As a novel noncoding gene fragment, circRNAs participate in various biosynthetic courses as well as the occurrence of diseases. Compared with other linear RNA fragments, circRNAs do not have the 5\u2032\u2010terminal cap structure or the 3\u2032\u2010end polyA\u2010tail structure, instead, circRNAs are closed\u2010loop structures formed by covalent bonds.CircRNAs are primarily derived from protein\u2010coding exons, they are noncoding sequences formed via reverse shearing of pre\u2010mRNAs during transcription.CircRNAs are abnormally expressed in a variety of diseases. CircRNAs act as a \u201csponge\u201d\u00a0to specifically adsorb miRNAs, prevent them from binding to the target genes and thus inhibit target gene regulation.4CircRNAs are widely expressed in the whole blood, platelets, and exosomes in the hematological system.55.1AML belongs to a hematological malignancy featured with abnormal proliferation of immature myeloid cells, which affect the normal formation of bone\u2010marrow hematopoietic cells.CircRNAs exert key roles in AML. The dysregulation of circRNA expression may result from the abnormal damage in leukemia cells and participate in AML pathogenesis and the mechanism of chemotherapeutic resistance. circMYBL2 was found to exist more abundantly in AML patients carrying FLT3\u2010ITD mutations.APL is an uncommon type of AML featured with the formation of PML\u2010RAR\u03b1 fusion protein.5.2BCR\u2010ABL fusion gene and expression of the BCR\u2010ABL1 fusion protein,CML is a malignant myeloid proliferative tumor occurring in pluripotent hematopoietic stem cells with an annual incidence of 1\u22122 per 100,000 people.In addition to the BCR\u2010ABL fusion gene, there are also certain ncRNAs that regulate the transcription and translation of specific genes and participate in the progress of CML. The upregulation or downregulation of circRNAs takes an important part in assessing the prognosis, pathogenesis, and resistance to chemotherapeutic drugs of CML.5.3ALL is a common malignant tumor in childhood, most of which are genetically heterogeneous tumors induced by malignant proliferation of lymphoid progenitor cells with gene mutations, accompanied by varying degrees of development or differentiation arrest.5.4+ B lymphocytes in bone marrow, peripheral blood, spleen, and lymph nodes.CLL is a chronic lymphoproliferative disease of B cells, featured by the continuous accumulation of monoclonal CD5Current studies mainly focus on circRNAs originating from the nuclear genome, however, the biological and clinical properties of mitochondrial genome\u2010derived (mt) circRNAs remain sparsely characterized, particularly in CLL. Mc\u2010COX2, a kind of mt\u2010circRNA, was abundantly presented in CLL patient\u2010derived plasma exosomes and positively related to leukemogenesis and deteriorated condition in CLL patients.6Currently, the research on circRNAs has become a hot spot. CircRNAs can function as miRNA targets, transcription regulators, protein adapters, or protein translation factors, exerting numerous regulatory roles by sponging specific miRNAs. CircRNAs show high abundance and evolutionary conservation across species, characterized by tissue/cell\u2010specific expression. More importantly, circRNAs could be extensively detected in peripheral blood, presenting the feasibility as noninvasive biomarker. Therefore, circRNAs play latently important roles in the early diagnosis, prognostic evaluation, pathogenesis, and chemotherapeutic resistance of leukemia, as well as the proliferation, differentiation, and progression of leukemia cells.However, compared with other linear RNAs, the research on circRNAs is still very limited, many problems need to be solved before their application in preclinical and clinical studies. For example, the current approaches for quantifying circRNAs have shown certain limitations that restrain the development of clinically applicable quantitative assays. A recent study analyzed the expression profile of circRNAs in several B cell malignancies via high\u2010throughput RNA\u2010seq,\u00a0and quantified multiple differentially expressed circRNAs by NanoString technology.Deng Wei: conceived, prepared, and revised the manuscript.\u00a0Deng Wei, Chao Rong, and Zhu Shengdong: made the data acquisition and interpretation. All authors approved the final manuscript for publication.The authors declare no conflict of interest."}
{"text": "Sci., 2022, https://doi.org/10.1039/d2sc04969d.Correction for \u2018An exchange coupled  During the editorial production of the finished article, the graphics associated with The intended version of The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "The authors regret their names were incorrectly published. This has been corrected as above. The authors would like to apologise for any inconvenience caused."}
{"text": "Journal of Healthcare Engineering has retracted the article titled \u201cCircRNA RERE Promotes the Oxidative Stress-Induced Apoptosis and Autophagy of Nucleus Pulposus Cells through the miR-299-5p/Galectin-3 Axis\u201d [-3 Axis\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifiThe authors do not agree to the retraction."}
{"text": "Pseudokirchneriella subcapitata by Monte Carlo approach\u2019 by Shahram Lotfi et al., RSC Adv., 2022, 12, 24988\u201324997, https://doi.org/10.1039/D2RA03936B.Correction for \u2018Ecotoxicological prediction of organic chemicals toward  The authors regret the omission of one of the co-corresponding authors\u2019 email addresses from the original manuscript. The corrected email addresses are shown below.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Had we been aware of this important prior work,we certainly would have referenced it. For this reason we are nowpublishing this minor correction so the prior article is properlycited and the two articles in the record (and on indexing services)are more transparent to the community.Near the time of the submissionof our now published manuscript"}
{"text": "The given name and family name of all the authors were reversed in the original version of the publication. It has been corrected with this erratum."}
{"text": "DOI: 10.1039/C9RA08707ACorrection for \u2018Boron-doped few-layer graphene nanosheet gas sensor for enhanced ammonia sensing at room temperature\u2019 by Shubhda Srivastava  The authors regret that affiliation b was incorrectly provided as Academy of Scientific and Innovative Research (AcSIR), CSIR-National Physical Laboratory Campus, Dr K S Krishnan Road, New Delhi 110012, India.The correct details are provided in the Affiliations section of this document.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "To solve the problem of inflexibility of offline hand\u2013eye calibration in \u201ceye-in-hand\u201d modes, an online hand\u2013eye calibration method based on the ChArUco board is proposed in this paper. Firstly, a hand\u2013eye calibration model based on the ChArUco board is established, by analyzing the mathematical model of hand\u2013eye calibration, and the image features of the ChArUco board. According to the advantages of the ChArUco board, with both the checkerboard and the ArUco marker, an online hand\u2013eye calibration algorithm based on the ChArUco board is designed. Then, the online hand\u2013eye calibration algorithm, based on the ChArUco board, is used to realize the dynamic adjustment of the hand\u2013eye position relationship. Finally, the hand\u2013eye calibration experiment is carried out to verify the accuracy of the hand\u2013eye calibration based on the ChArUco board. The robustness and accuracy of the proposed method are verified by online hand\u2013eye calibration experiments. The experimental results show that the accuracy of the online hand\u2013eye calibration method proposed in this paper is between 0.4 mm and 0.6 mm, which is almost the same as the offline hand\u2013eye calibration accuracy. The method in this paper utilizes the advantages of the ChArUco board to realize online hand\u2013eye calibration, which improves the flexibility and robustness of hand\u2013eye calibration. The application of industrial robots has greatly improved the production efficiency and product quality of enterprises ,2. HowevCompared with the hand\u2013eye calibration method based on the 3D calibrators, the hand\u2013eye calibration method based on 2D images is more widely used. Since the feature points of the checkerboard pattern are easy to detect, most of the classical hand\u2013eye calibration theories use it as the calibrator ,11,12. ITo solve these problems, an online hand\u2013eye calibration method based on the ChArUco board is proposed in this paper. The ChArUco board is a combination of an ArUco marker and a checkerboard, and possesses the advantages of both. The ChArUco board rectifies the shortcomings of the ArUco marker\u2019s poor positioning accuracy by using the high sub-pixel detection accuracy of the checkerboard corners of the calibration board, and solves the problem of the poor anti-interference of the checkerboard through the unique encoding of the ArUco marker. Based on the detection advantages of the ChArUco board, this paper designs a closed-loop feedback adjustment system for the robot to realize online hand\u2013eye calibration of eye-in-hand mode.The other parts of the paper are arranged as follows: R and the translation vector t. The essence of hand\u2013eye calibration was to solve the problem of AX = XB [The purpose of hand\u2013eye calibration was to calculate the coordinate transformation relationship between the camera coordinate system, and the robot coordinate system, that is, to solve the rotation matrix  AX = XB ,18,19. HAs shown in Formula (2), the hand\u2013eye calibration matrix could be solved through the calculation of the robot pose transformation, and the camera extrinsic parameters.Let According to the described mathematical model of hand\u2013eye calibration, the solution process of hand\u2013eye calibration needed to obtain the homogeneous matrix ArUco markers have the advantages of flexibility and easy detection. However, the ArUco marker has the problem that the detection accuracy of the edge corners is not high. Even if sub-pixel processing is performed on the corner, the expected accuracy is still not achieved. The black and white interlaced pattern of the checkerboard makes the corners easy to detect. Unfortunately, the flexibility of the checkerboard is not as extensive as the ArUco marker. When the checkerboard was used as a calibration object, the checkerboard needed to be completely visible, and could be blocked. The ChArUco board possessed the advantages of both the checkerboard and the ArUco marker. In addition, the ChArUco board ameliorated the deficiencies of both. As shown in As shown in In addition, the pose of each recognizable encoding pattern on the ChArUco board could be computed as if the pose of a single ArUco marker were recognized. Based on the detection advantages of the ChArUco board, this paper designed a closed-loop feedback adjustment system for the robot to realize online hand\u2013eye calibration. As shown in n method . In addiIn this paper, Hikvision\u2019s MV-CE050-30GM camera, FUJINON\u2019s CF8ZA-1S lens and ABB\u2019s IRB2600-20 robot were used to build the experimental platform. The experimental platform is shown in Before the experiment, the internal parameters of the camera used in the experiment were calibrated. The calculation results of camera internal parameters were as follows:In this paper, 10 sets of hand\u2013eye calibration independent experiments were carried out, and 25 sets of hand\u2013eye calibration data, based on the ArUco marker, the checkerboard and the ChArUco board, were collected in each experiment. The calculation results of camera extrinsic parameters for the three calibration methods are shown in In online hand\u2013eye calibration experiments based on the ChArUco board, 10 sets of online hand\u2013eye calibration independent experiments were carried out. In a single set of independent experiments, 25 sets of robot teaching actions were set, and the ChArUco board was placed away from the center of the camera\u2019s field of view. In addition, as shown in Based on the above experimental results, it can be seen that the online hand\u2013eye calibration method proposed in this paper could effectively solve the problem of online hand\u2013eye calibration, and had good performance in robustness and accuracy.In order to reflect the practicability of this method, the performance of this method was compared with the existing methods, and the results are shown in Aiming at the problem of inflexible offline hand\u2013eye calibration in eye-in-hand mode, an online hand\u2013eye calibration method based on the ChArUco board was proposed in this paper. The method in this paper utilized the advantages of the ChArUco board, which has the advantages of high sub-pixel recognition accuracy of the checkerboard corner, and the strong flexibility of the ArUco marker, to realize the positioning of the calibration board. The position relationship between the calibration board and the robot was established. Then, the closed-loop feedback automatically adjusted the robot by detecting the position of the ChArUco board in the image. Enough hand\u2013eye calibration data were collected by robot automatic control to complete online hand\u2013eye calibration. In this paper, the accuracy of hand\u2013eye calibration based on the ChArUco board was verified by comparative experiments. The robustness and accuracy of the method were verified by online hand\u2013eye calibration experiments.In the current research of this paper, the influence of the hand\u2013eye calibration caused by the robot motion error was not considered. In future work, we will study the influence of robot motion error on hand\u2013eye calibration accuracy, and consider how to eliminate the influence of robot motion error. This will be an interesting and meaningful research direction."}
{"text": "Computational Intelligence and Neuroscience has retracted the article titled \u201cLNCRNA XIST Inhibits miR-377-3p to Hinder Th17 Cell Differentiation through Upregulating ETS1\u201d [Following an investigation conducted by the Hindawi Research Integrity team , signifi"}
{"text": "There was an error in the original publication  in the fJ. Gen. Virol.2010, 91, 2341\u20132350.\u201d (It has been changed to Ref. [112] in the updated version). The correct reference is \u201cRissanen, I.; Stass, R.; Zeltina, A.; Li, S.; Hepojoki, J.; Harlos, K.; Gilbert, R.J.C.; Huiskonen, J.T.; Bowden, T.A.; Sundquist, W.I. Structural Transitions of the Conserved and Metastable Hantaviral Glycoprotein Envelope. J. Virol.2017, 91.\u201d . With this correction, the order of some references has been adjusted accordingly.In addition, there is an error in the reference for the following sentence: \u201cThe dissociation of the Gn/Gc complexes at a low pH is thought to make the tripartite fusion loop accessible for membrane fusion, although this dissociation does not seem to trigger membrane fusion and seems to even be reversible [39].\u201d The reference here in the original publication is \u201cHepojoki, J.; Strandin, T.; Wang, H.; Vapalahti, O.; Vaheri, A.; Lankinen, H. Cytoplasmic tails of hantavirus glycoproteins interact with the nucleocapsid protein. The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "All the authors agree to the publication of this corrigendum, and apologize to the readership for any inconvenience caused.The authors have re-examined their original data, and have realized that this figure was inadvertently assembled incorrectly owing to the similarity of the data shown in the two affected panels. The revised version of"}
{"text": "Moreover, a universal reverse primer was used for the reverse primer of miR-15b-5p, as provided by the kit ; however, a different primer sequence used in the authors\u2019 lab was erroneously written as the reverse primer of miR-15b-5p in the manuscript. Finally, note that the title was published with a typographical error: \u201cmiR-15p-5p\u201d in the title should have been written as \u201cmiR-15b\u22125p\u201d, as appeared elsewhere throughout the paper, and the corrected title is presented above.Following the publication of this article, an interested reader drew to the authors\u2019 attention that the primer sequences written for lncRNA DQ786243 and miR-15b-5p on p. 2 in the study were incorrect. Upon requesting an explanation of these errors from the authors, they realized that, regarding the sequence of the reverse primer for lncRNA DQ786243, three nucleotides were omitted from its 3\u2019-end . Regarding the primers of miR-15b-5p, the authors used the mature miR-15b-5p sequence as the forward primer; however, they inadvertently overlooked replacing U with T in the description of the forward primer of miR-15b-5p, and therefore the sequence of the forward primer of miR-15b-5p on line 27 should have been written as 5\u2019-Molecular Medicine Reports for allowing them the opportunity to publish this corrigendum, and all the authors agree with its publication. The authors also regret the inconvenience that these mistakes have caused.The authors are grateful to the Editor of"}
{"text": "In the original publication, errors were found in Figure 6D and Table S1. During statistics analysis, the Spearman analyze between PTPROt mRNA expression and \u03b3-GT were misused with the data of ALT in Figure 6D and Table S1. The correct figures and table are shown below. The authors confirm that these corrections do not change the result interpretation or conclusions of the article. The authors are deeply sorry and sincerely apologize for any inconvenience or misunderstanding that may have caused."}
{"text": "Retraction Note: Stem Cell Research & Therapy (2021) 12:85https://doi.org/10.1186/s13287-021-02154-7The authors have retracted this article. After publication the authors noted that they used the incorrect \u03b2-actin protein expression data in Fig.\u00a01E. Yao Fu did not participate in the experiments presented and were included in the author list without their permission. Meng Zhou, Yao Fu and Zi Wang agree to this retraction. Mingjiao Chen and Jin Li do not agree to this retraction."}
{"text": "The 1H NMR spectra show the appearance and disappearance of two of the characteristic peaks for 4-methylphenyl in the reactions to synthesise PEG\u2013N\u2013OH2 . Subsequently, the characteristic methyl peak of the macroinitiator (PEG\u2013N\u2013Br2) is also observed . The MALDI-TOF MS spectrum of the product of each reaction shows a set of peaks with a spacing of 44 m/z . The main peak position changes as the terminal group changes. The absolute molecular weight of each product obtained through MALDI-TOF MS matches well with the calculated molecular weight.The authors have added additional The electronic supplementary information (ESI) of the original article has been updated to reflect these changes.1H NMR spectrum, shown in In addition, the authors regret that the signal for the CH\u2013Br group in the The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "After having been in contact with the authors, they agreed with the decision to retract the paper. The Editor apologizes to the readership for any inconvenience caused.Subsequently to the publication of the above article, a concerned reader drew to the Editors' attention that the cell invasion and migration assay data shown in Fig. 3B and D were strikingly similar to data appearing in different form in other articles by different authors. Owing to the fact that these contentious data in the above article had already been published elsewhere, or were already under consideration for publication, prior to its submission to"}
{"text": "PLOS ONE Editorial Board member. This does not alter the authors\u2019 adherence to all the PLOS ONE policies on sharing data and materials.The Competing Interests statement for this article  is incomThe VSL#3 used in this study was obtained from VSL Pharmaceuticals and produced by Danisco/Dupont in the US."}
{"text": "Awais Shabbir was mistakenly written as \u201cMuhammad Awais\u201d in the original publication . The corAuthor Contributions: Conceptualization, A.S., M.S. (Muhammad Sharif), K.A., A.I.A. and M.S. (Muhammad Saeed); methodology, A.S., M.S. (Muhammad Saeed), K.A., A.I.A. and M.S. (Muhammad Sharif); software, A.S. and M.S. (Muhammad Saeed); validation, A.S., M.S. (Muhammad Sharif), K.A., A.I.A. and M.S. (Muhammad Saeed); investigation, A.S., M.S. (Muhammad Sharif), K.A., A.I.A. and M.S. (Muhammad Saeed); resources, A.D.C. and M.A.; data curation, A.S., M.S. (Muhammad Sharif), K.A., A.I.A. and M.S. (Muhammad Saeed); writing\u2014original draft preparation, A.S., M.S. (Muhammad Sharif), K.A., A.I.A. and M.S. (Muhammad Saeed); writing\u2014review and editing, A.D.C. and M.A.; visualization, A.D.C. and M.A.; supervision, A.D.C. and M.A.; project administration, A.D.C. and A.S. All authors have read and agreed to the published version of the manuscript.There was an error in the original publication. The name of pH meter \u201cOrion portable pH meter model 230A, pH triode electrode; Orion Research, Inc., Boston, MA, USA\u201d was mistakenly written.paragraph number 4 and line numbers 6\u20138:A correction has been made to the above-mentioned error in Materials and Methods, \u201cPortable pH meter  was used for immediate ruminal pH determination\u201dThe authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "Correction: World J Surg (2019) 43:1928\u20131934 10.1007/s00268-019-04981-5Since the publication of this work, S. Kanavati has changed their name from O. Kanavati. This has now been amended."}
{"text": "In the original publication , there wIn the original publication , the funFunding: CIBERDEM is an initiative from Instituto de Salud Carlos III . M.G.-C. held a predoctoral fellowship from the Ministerio de Educaci\u00f3n, Cultura y Deporte, FPU15/03005. This project was developed within the framework of the Doctorate in the Department of Medicine, Autonomous University of Barcelona."}
{"text": "Journal of Healthcare Engineering has retracted the article titled \u201cAn Early Warning of Atrial Fibrillation Based on Short-Time ECG Signals\u201d [Signals\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifiThe authors do not agree to the retraction."}
{"text": "RSC Advances article due to a significant amount of unattributed text overlap with The Royal Society of Chemistry hereby wholly retracts this Somayeh Sohrabi, Nour kassir and Mostafa Keshavarz Moraveji have not agreed to the retraction.RSC Advances Executive Editor.Signed: Laura Fisher, th November 2022.Date: 25"}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors\u2019 attention by a concerned reader that certain of the B-scan ocular ultrasound images portraying cardiac function shown in Fig. 4A and B and Fig. 5A were strikingly similar to data appearing in different form in other articles published by different authors who were based at different institutions. Owing to the fact that the contentious data in the above article had already been published elsewhere prior to its submission to"}
{"text": "Single\u2010crystal X\u2010ray structure analyses and theoretical studies give evidence of through\u2010space delocalization of  \u03c0\u2010electrons of peripheral (hetero)aromatic rings in toroidal and [4]catenated topology (light blue rings).Sterically highly crowded and twisted thienylene\u2010phenylenes are synthesized and structurally characterized. Single\u2010crystal X\u2010ray structure analyses and theoretical studies give evidence of through\u2010space delocalization of  More recently, the sophisticated concepts were used by the M\u00fcllen group to prepare to date inconceivable structures of defined graphene nanoribbons as a new family of carbon\u2010based semiconductors via solution and on\u2010surface chemistry. In contrast to graphene, the band gap in these nanoribbons is opened due to the geometric confinement and therefore can be applied in electronic application such as switches and transistors. A highly challenging project in this category was the synthesis of \u201cphenylogous\u201d model compounds for cubic graphite as hypothetical carbon allotrope which fascinates due to an exceptional 3D structure entirely comprising benzene rings, from which each of them is connected to six other rings. Such a model and precursor subunit of \u201cphenylogous\u201d cubic graphite with the extended hexaphenylbenzene structure 3 was formed in a threefold [4+2]\u2010cycloaddition\u00a0of tetracyclone 1 and triply ethynylated quaterphenyl 2 under harsh reaction conditions and isolated in 2% yield besides the doubly reacted product 4 (34% yield) biphenyl 6 also revealed steric hindrance and propeller\u2010like arrangement of the peripheral thiophene rings, but reduced steric congestion and distortion effects due to the smaller geometric extension of thiophene compared to benzene. Interestingly, through\u2010space \u03c0\u2010conjugation of the ipso\u2010carbons in a toroidal and catenated topology has been evidenced from X\u2010ray structure analysis and theoretical calculations (anisotropy of the induced current density (ACID)) benzene )) Figure1. Furt3 by corresponding thiophene units to result in targeted trigonal thienylene\u2010phenylene 9  and the pure product was collected in 3% yield as colorless solid. Increased reaction temperature had negative impact and did not lead to higher yields, because the substrates started increased decomposition. As the main product, the doubly reacted 10 was isolated in 54% yield by column chromatography.The preparation of crowded thienylene\u2010phenylene 9 was assigned by high\u2010resolution mass spectrometry (HRMS), which showed the intense molecular\u2010ion peak at m/z = 1711.4489  for the \u03b2\u2010protons in 3\u2010position of the inner three thiophenes is observable .The molecular structure of dendrimer 9 but with an increased ratio of thiophene rings by similar reaction of precursor 8 and tetra(2\u2010thienyl)cyclopentanone 11 resulted in only the mono\u2010reacted derivative 12 in low yield  solution. The molecule crystallizes in the monoclinic space group C2/c with eight molecules in the unit cell  \u00c5, b = 7.352(3) \u00c5, c = 16.854(8) \u00c5, and \u03b1\u00a0= 90\u00b0, \u03b2 = 100.86(2)\u00b0, \u03b3 = 90\u00b0 benzene\u20101,3,5\u2010triyl]tris}trithiophene ll Figure2c. The 8 presents disorder in five of the six thiophene rings due to the possibility of syn\u2010anti arrangment whereby keeping the same molecular volume. Higher torsion angles between 48.0(2)\u00b0 and 81.3(2)\u00b0 were identified for the thiophenes directly attached to the central benzene ring, whereas the thiophenes connected through the ethynylene bridge are closer to planarity by 18.4(2)\u00b0 to 27.1(2)\u00b0  to 1.486(3) \u00c5. These distances are undercut by the ones to the ipso\u2010C atoms of the ethynyl bridges which lie between 1.433(3) and 1.437(3) \u00c5  \u00c5, b = 8.8041(7) \u00c5, c = 20.8851(9) \u00c5, and \u03b1\u00a0= 104.484(4)\u00b0, \u03b2\u00a0\u00a0= 97.403(4)\u00b0, \u03b3\u00a0= 92.008(4)\u00b0  via [2+2+2+2]\u2010cycloaddition,[12]\u00a0was introduced by Reppe et\u00a0al. and has been intensively investigated since then. Besides nickel, diverse transition metals such as cobalt, rhodium, palladium, ruthenium, and others were used and the general mechanism of the catalytic cycle was established. With this background, we have alternatively applied the Wilkinson catalyst [RhCl(PPh3)3] for the cyclooligomerization of butadiyne 7. As in the case of Co2(CO)8 as catalyst, hexasubstituted benzene 8 was isolated as main product in a moderate yield of 10% besides cyclopentamers 13 after tedious chromatographic work\u2010up. However, an additional fraction comprising a tetrameric product was isolated in 2% yield which in HRMS showed a molecular ion peak at the mass of a cyclotetramer (m/z = 855.96114)  \u00c5, b = 11.4821(4) \u00c5, c = 19.3739(5) \u00c5, and \u03b1\u00a0= 102.118 (3)\u00b0, \u03b2\u00a0= 96.605(3)\u00b0, \u03b3\u00a0= 98.016(3)\u00b0. In the refinement of the X\u2010ray structure, disorder due to syn\u2010anti\u2010isomerization in six thiophene rings has been found. Key parameters of the crystal structure refinement are summarized in Table Colorless single crystals of 5\u2010(thien\u20102\u2010yl)\u20104\u2010(thien\u20102\u2010ylethynyl)\u20106\u2010benzothiophene unit are localized with mean bond alternance of 0.03 \u00c5 which is typical for benzo[b]thiophenes  which indicates lack of conjugation between the aromatic rings as a consequence of the crowded structure. On the contrary, the ethynyl\u2010bridged thiophenes remain closer to planarity (17.1\u00b0 and 25.4\u00b0) with respect to the central benzene ring chromophores is reduced leading to hypsochromically shifted absorption and emission compared to the more planar 8.The optoelectronic properties of twisted phenylene\u2010thienylene precursor 2.5 The ACID scalar field is interpreted as the density of delocalized electrons and can be plotted as an isosurface buta\u20101,3\u2010diyne 7, tetracyclone 1, and 2,3,4,5\u2010tetra(2\u2010thienyl)cyclopenta\u20102,4\u2010dien\u20101\u2010on [1319] were prepared according to literature. Dried tetrahydrofuran  was used from an MB SPS\u2010800 solvent purification system (MBraun). 1,4\u2010Dioxane (Merck) was dried over CaH2 and distilled prior to use. DCM, methanol, petroleum ether (PE), and n\u2010hexane were purchased from VWR and distilled prior to use. n\u2010Butyl lithium  was purchased from Acros Organics, Co2(CO)8 from Sigma Aldrich. Thin\u2010layer chromatography was performed on aluminum plates, precoated with silica gel, Merck Si60 F254. Preparative column chromatography was carried out on glass columns packed with silica gel, Merck Silica 60, particle size 40\u201363\u00a0\u00b5m. HPLC was performed on a Shimadzu CBM\u201020A equipped with an SPD\u201020A UV/VIS detector and an LC\u20108A solvent system with a Macherey\u2010Nagel column (Nucleosil 100\u20135 NO2). NMR spectra were recorded on a Bruker Avance 400  at 293\u00a0K. Chemical shift values (\u03b4) were given in parts per million (ppm) and were calibrated on residual nondeuterated solvent peaks  as an internal standard. The splitting patterns were labeled as follows: s (singlet), d (doublet), dd (doublet of doublet), and m (multiplet). Melting points were measured using a B\u00fcchi Melting Point M\u2010565. High\u2010resolution mass spectra  were recorded on a Bruker Solarix , using trans\u20102\u2010[3\u2010(4\u2010tert\u2010butylphenyl)\u20102\u2010methyl\u20102\u2010propenylidene]malononitrile (DCTB) as a matrix. Elemental analyses were performed on an Elementar Vario EL. UV/Vis absorption spectra were recorded on a Perkin Elmer Lambda 19 spectrometer. Fluorescence spectra were recorded on a Perkin Elmer LS 55 Luminescence spectrometer. Cyclic voltammetry experiments were carried out using a computer\u2010controlled Autolab PGSTAT30 potentiostat in a three\u2010electrode single\u2010compartment cell with a platinum working electrode, a platinum wire counter electrode, and a Ag/AgCl reference electrode. All potentials were internally referenced to the ferrocene/ferricenium couple. The diffraction data of crystals of 8, 9, and 12 were collected in a stream of nitrogen at 180 K on an Agilent SuperNova, Cu at zero, Atlas CCD using graphite\u2010monochromated Cu K\u03b1 radiation. Data collection strategy was performed with the APEX2 software, data reduction, absorption correction, and cell refinement with CrysAlisPro 171. The structure was solved by direct methods with SHELXL\u20102016/6, revealing all atoms of the derivatives. H atoms were discernible from difference Fourier maps during refinement on F2 with SHELXL\u201097. For the final model, all atoms were refined anisotropically.1,4\u2010Dibenzene\u20101,3,5\u2010triyl]tris}trithiophene8: 1,4\u2010Di(thien\u20102\u2010yl)buta\u20101,3\u2010diyne 7  and Co2(CO)8  in 20\u00a0mL abs. 1,4\u2010dioxane were stirred at 110 \u00b0C for 2 days. The solvent was removed and the residue was purified by column chromatography (PE/DCM 3:1). Phenylene\u2010thienylene 8  was obtained as light\u2010yellow solid after twofold recrystallization from methanol and n\u2010hexane/DCM. M.p. 276\u2013279 \u00b0C; H NMR : \u03b4 7.63  = 5.1\u00a0Hz, 4J = 0.9\u00a0Hz, 3H, 5\u2010Th\u03b1\u2010H), 7.40\u20137.37 , 7.19  = 5.0, 3.6\u00a0Hz, 3H, 4\u2010Th\u03b2\u2010H), 6.92  = 5.0, 3.7\u00a0Hz, 3H, 4\u2032\u2010Th\u03b2\u2010H), 6.87  = 3.6, 4J = 1.0\u00a0Hz, 3H, \u03b2\u20103\u2032\u2010ThH) ppm; 13C NMR : \u03b4 139.5, 138.8, 132.8, 130.1, 128.9, 127.7, 127.3, 127.0, 125.6, 123.1, 92.8, 91.7\u00a0ppm; HRMS (MALDI\u2010FTICR) m/z: calcd. for C52H30S10: 641.97273; found 641.97251 [M]+ (\u03b4m/m = 0.7\u00a0ppm), 892.11948 [M+DCTB]+, 1142.26549 [M+2DCTB]+; CCDC 1884748.13 were obtained as side products and were separated by HPLC . Isolated derivative A: 1H NMR : \u03b4 7.58  = 5.1\u00a0Hz, 4J = 1.2\u00a0Hz, 1H, 5\u2010Th\u03b1\u2010H), 7.45  = 3.6\u00a0Hz, 4J = 1.2\u00a0Hz, 1H, 3\u2010Th\u03b2\u2010H), 7.42  = 5.0\u00a0Hz, 4J = 1.2\u00a0Hz, 1H, 5\u2010Th\u03b1\u2010H), 7.37  = 5.0\u00a0Hz, 4J = 1.2\u00a0Hz, 2H, 5\u2010Th\u03b1\u2010H), 7.34  = 4.9\u00a0Hz, 4J = 1.4\u00a0Hz, 2H, 5\u2010Th\u03b1\u2010H), 7.27  = 5.1\u00a0Hz, 4J = 1.2\u00a0Hz, 1H, 5\u2010Th\u03b1\u2010H), 7.25\u20137.21 , 7.06\u20137.02 , 7.01\u20136.95 , 6.94\u20136.87 , 6.83  = 3.6\u00a0Hz, 4J = 1.2\u00a0Hz, 2H, 3\u2010Th\u03b2\u2010H), 6.78  = 3.7\u00a0Hz, 4J = 1.1\u00a0Hz, 1H, 3\u2010Th\u03b2\u2010H) ppm; HRMS (MALDI\u2010FTICR) m/z: calcd. for C60H30S10: 1069.95491; found m/z = 1069.95351 [M]+ (\u03b4m/m = 1.3\u00a0ppm), 1321.10808 [M+DCTB]+. Isolated derivative B: 1H NMR : \u03b4 7.57  = 5.1\u00a0Hz, 4J = 1.2\u00a0Hz, 1H, 5\u2010Th\u03b1\u2010H), 7.55  = 5.1\u00a0Hz, 4J = 1.2\u00a0Hz, 1H, 5\u2010Th\u03b1\u2010H), 7.43  = 3.6\u00a0Hz, 4J = 1.2\u00a0Hz, 1H, 3\u2010Th\u03b2\u2010H), 7.38\u20137.34 , 7.32\u20137.27 , 7.26\u20137.17 , 7.05  = 3.6\u00a0Hz, 4J = 1.2\u00a0Hz, 2H, 3\u2010Th\u03b2\u2010H), 6.98  = 5.1\u00a0Hz, 3J = 3.6\u00a0Hz, 2H, 4\u2010Th\u03b2\u2010H), 6.95\u20136.94 , 6.93\u20136.88 , 6.85  = 3.6\u00a0Hz, 4J = 1.2\u00a0Hz, 1H, 3\u2010Th\u03b2\u2010H), 6.82  = 3.7\u00a0Hz, 4J = 1.2\u00a0Hz, 2H, 3\u2010Th\u03b2\u2010H), 6.73  = 5.1, 3.6\u00a0Hz, 1H, 4\u2010Th\u03b2\u2010H), 6.37  = 3.6, 4J = 1.2\u00a0Hz, 1H, 3\u2010Th\u03b2\u2010H) ppm; HRMS (MALDI\u2010FTICR) m/z: calcd. for C60H30S10: 1069.95491; found m/z = 1069.95401 [M]+ (\u03b4m/m = 0.8\u00a0ppm), 1320.09927 [M+DCTB]+.Derivatives of cyclopentamers 1,3,5\u2010Tris(thien\u20102\u2010yl)\u20102,4,6\u2010tris{benzene}\u2010benzene9: Trithiophene 8  and tetracyclone 1  were stirred at 265 \u00b0C in the melt for 24 h. Dendrimer 9  was obtained as colorless solid after purification by column chromatography (PE/DCM 3:1 \u2192 1:1) and purification by HPLC . M.p. >\u00a0350 \u00b0C; 1H NMR : \u03b4 7.23  = 5.1\u00a0Hz, 4J = 1.1, 2H, \u03b1\u20105\u2032\u2010ThH), 7.21  = 5.1\u00a0Hz, 4J = 1.2, 1H, \u03b1\u20105\u2032\u2010ThH), 6.89  = 5.0\u00a0Hz, 4J = 1.2\u00a0Hz, 1H, \u03b1\u20105\u2010ThH), 6.88\u20136.77 , 6.76  = 5.1, 3.8\u00a0Hz, 3H, \u03b2\u20104\u2032\u2010ThH), 6.74\u20136.61 , 6.59\u20136.55 , 6.48\u20136.43 , 6.42  = 5.1, 3.8\u00a0Hz, 2H, \u03b2\u20104\u2010ThH), 6.37\u20136.35 , 5.38\u20135.29  ppm; 13C NMR : \u03b4 142.9, 142.7, 142.3, 142.2, 142.1, 141.5, 141.4, 141.2, 141.2, 140.4, 139.5, 138.5, 138.2, 136.7, 136.7, 132.8, 131.4, 131.2, 130.7, 130.6, 126.8, 126.7, 126.7, 126.6, 126.2, 126.0, 126.0, 125.8, 125.5, 125.2, 125.0, 124.9, 124.9, 124.7, 124.6, 124.2, 123.3\u00a0ppm; HRMS (MALDI\u2010FTICR) m/z: calcd. for C120H78S6: 1710.44278; found 1710.43980 [M]+ (\u03b4m/m = 1.7\u00a0ppm), 1734.43117 [M+Na]+, 1960.59622 [M+DCTB]+; CCDC 1884754.2,2\u2032,2\u2033,2\u2034,2\u2033\u2033\u2010\u2010\u20102\u2033,3\u2032,4\u2033,6\u2033,6\u2034\u2010pentayl)pentathiophene10  was obtained as main product after purification by column chromatography (PE/DCM 3:1 \u2192 1:1). M.p. >\u00a0300 \u00b0C; 1H NMR : \u03b4 7.44  = 5.1, 3.0\u00a0Hz, 1H, \u03b2\u20104\u2010ThH), 7.38\u20137.34 , 7.18  = 5.1\u00a0Hz, 4J = 1.1\u00a0Hz, 1H, \u03b1\u20105\u2010ThH), 6.98\u20136.91 , 6.90\u20136.55 , 6.55\u20136.49 , 6.43  = 5.1, 3.6\u00a0Hz, 1H, \u03b2\u20104\u2010ThH), 6.36  = 5.1, 3.6\u00a0Hz, 1H, \u03b2\u20104\u2010ThH), 5.62\u20135.58 , 5.54  = 3.6, 4J = 1.2\u00a0Hz, 1H, \u03b2\u20103\u2010ThH), 5.41  = 3.6, 4J = 1.2\u00a0Hz, 1H); 13C NMR : \u03b4 143.0, 142.9, 142.7, 142.7, 142.7, 142.6, 142.5, 141.7, 141.5, 141.4, 141.2, 140.7, 139.9, 139.7, 139.1, 139.1, 138.2, 138.0, 137.6, 136.0, 132.7, 132.1, 131.9, 131.7, 131.5, 131.3, 131.1, 130.6, 127.5, 126.9, 126.9, 126.8, 126.8, 126.7, 126.6, 126.4, 126.1, 126.1, 125.7, 125.6, 125.6, 124.6, 124.5, 124.5, 124.0, 95.1\u00a0ppm . HRMS (MALDI\u2010FTICR) m/z: calcd. for C92H58S6: 1354.28573; found 1354.28541 [M]+ (\u03b4m/m = 0.24\u00a0ppm).4\u2010(Thien\u20102\u2010yl)\u20106\u2010(thien\u20102\u2010ylethinyl)\u20105\u2010benzo[b]thiophene14: 1,4\u2010Di(thien\u20102\u2010yl)buta\u20101,3\u2010diyne 7  and [RhCl (PPh3)3]  in 20\u00a0mL abs. o\u2010xylene were stirred at 130 \u00b0C for 3 days. The reaction was stopped by addition of water. The separated organic phase was extracted with DCM and washed with water and dried with sodium sulfate. After removal of the solvent, column chromatography  and HPLC  delivered benzo[b]thiophene 12 as beige\u2010colored solid . M.p. >\u00a0400 \u00b0C; 1H NMR : \u03b4 7.87  = 0.9\u00a0Hz, 1H, 5\u2010PhH), 7.58  = 5.1\u00a0Hz, 4J = 1.2\u00a0Hz, 1H, 5\u2010Th\u03b1\u2010H), 7.47  = 5.6\u00a0Hz, 1H, 4\u2033\u2033\u2010Th\u03b2\u2010H) 7.45  = 3.6\u00a0Hz, 4J = 1.2\u00a0Hz, 1H, 3\u2010Th\u03b2\u2010H), 7.40  = 4.9\u00a0Hz, 4J = 1.0\u00a0Hz, 1H, 5\u2010Th\u03b1\u2010H), 7.39  = 5.3\u00a0Hz, 5J = 0.7\u00a0Hz, 1H, 5\u2033\u2033\u2010Th\u03b1\u2010H), 7.31  = 5.1\u00a0Hz, 4J = 1.2\u00a0Hz, 1H, 5\u2034\u2010Th\u03b1\u2010H), 7.24  = 5.1, 3.5\u00a0Hz, 1H, 4\u2010Th\u03b2\u2010H), 7.22  = 5.1\u00a0Hz, 4J = 1.2\u00a0Hz, 2H, 5\u2032\u2010Th\u03b1\u2010H), 7.19  = 5.1\u00a0Hz, 4J = 1.2\u00a0Hz, 2H, 5\u2033\u2010Th\u03b1\u2010H), 7.13  = 3.6\u00a0Hz, 4J = 1.2\u00a0Hz, 1H, 3\u2010Th\u03b2\u2010H), 7.06  = 5.1, 3.6\u00a0Hz, 1H, 4\u2010Th\u03b2\u2010H), 7.00  = 5.2, 3.6\u00a0Hz, 1H, 4\u2034\u2010Th\u03b2\u2010H), 6.94  = 3.6\u00a0Hz, 4J = 1.2\u00a0Hz, 2H, 3\u2032\u2010Th\u03b2\u2010H), 6.88  = 5.1, 3.7\u00a0Hz, 2H, 4\u2032\u2010Th\u03b2\u2010H), 6.87  = 3.6\u00a0Hz, 4J = 1.2\u00a0Hz, 1H, 3\u2034\u2010Th\u03b2\u2010H), 6.84  = 5.1, 3.6\u00a0Hz, 2H, 4\u2033\u2010Th\u03b2\u2010H), 6.80  = 3.7\u00a0Hz, 4J = 1.2\u00a0Hz, 2H, 3\u2033\u2010Th\u03b2\u2010H) ppm; 13C NMR : \u03b4 141.4, 140.2, 140.0, 139.3, 139.2, 138.9, 138.4, 136.8, 132.6, 132.2, 130.7, 130.3, 130.0, 128.6, 128.6, 128.5, 127.9, 127.6, 127.2, 127.1, 126.9, 126.9, 126.8, 126.2, 126.1, 125.3, 124.2, 123.6, 123.3, 122.4, 94.3, 92.4, 92.2, 88.3\u00a0ppm; HRMS (MALDI\u2010FTICR): m/z berechnet f\u00fcr C48H34S8: 855.96382; gefunden: 855.96114 [M]+ (\u03b4m/m = 3.1\u00a0ppm), 1106.10659 [M+DCTB]+; CCDC 1884744.ACID: The anisotropy of the current density was calculated using ACID method implemented in the Gaussian09 D.01[18] program using NMR calculations with continuous set of gauge transformations (CSGT) and the IOp(10/93) option. For an adequate description of the expected through\u2010space conjugation, the Pople basis 6\u2013311+G** with diffuse functions and the standard B3LYP density functional was employed. The orientation of the magnetic field vector was orthogonal to the peripheral ring current and pointing toward the viewer.The authors declare no conflict of interest.Supporting InformationClick here for additional data file."}
{"text": "The authors regret that the article included the wrong image in Fig.\u00a05. This has now been amended.The authors would like to apologise for any inconvenience caused."}
{"text": "RSC Advances article. There is a significant amount of unattributed text overlap with articles by different author groups that were not cited, including articles published in Scientific Reports by Zhenjian Zhuo et al.1 and Carcinogenesis by Dong-Mei Zhang et al.2The Royal Society of Chemistry hereby wholly retracts this In addition, the raw data provided by the authors could not be used as verifiable raw data to validate the published western blot images.The considerable amount of unattributed text overlap, and lack of verifiable raw data, undermines the integrity and reliability of the entire article.Jie Liu agrees to the retraction. The other authors have been informed but have not responded to any correspondence regarding the retraction.RSC AdvancesSigned: Laura Fisher, Executive Editor, Date: 29th March 2022"}
{"text": "In the \u201cSpectral data modeling\u201d subsection of the \u201cResults\u201d section, there is an error in the fifth sentence of the first paragraph. The correct sentence is: \u201cCombining laser and sedimentation methods in Set2 improved the clay predictions with R2 values of 0.80\u20130.85.\u201dilr differences. The authors have provided a corrected version here.In There are errors in"}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors' attention by a concerned reader that data shown in various of the panels portraying the results from flow cytometric experiments in Fig. 2D, 5D and 6D were strikingly similar to data appearing in different form in other articles by different authors. Owing to the fact that the contentious data in the above article had already been published elsewhere, or were already under consideration for publication, prior to its submission to"}
{"text": "JCI Insight. 2018;3(16):e122204. https://doi.org/10.1172/jci.insight.122204Original citation: JCI Insight. 2023;8(4):e169136. https://doi.org/10.1172/jci.insight.169136Citation for this corrigendum: It has been brought to the authors\u2019 attention that the STR profile of the head and neck squamous cell carcinoma line UT-SCC-54C presented in Supplemental Table 1 is markedly different from that of UT-SCC-54A and UT-SCC-54B, which originated from the same patient. Upon further investigation, the authors have determined that the UT-SCC-54C cultures used in this study almost exclusively comprise colon cancer\u2013derived HCT116 cells, as demonstrated by STR, gene expression, and mutation profiling. The authors regret contamination of the UT-SCC-54C line reported here and confirm that uncontaminated UT-SCC-54C cultures are available from earlier frozen stocks. The authors have stated that the conclusions of the study are not affected."}
{"text": "This misrepresentation of data without appropriate attribution represents a severe abuse of the scientific publishing system. The authors did not respond to the request to retract the paper."}
{"text": "First nitroxides containing tellurium atom\u2019 by Jerzy Zakrzewski  The authors regret that incorrect text concerning names of specific chemical compounds were included in the original article.3a, 3-(phenyltellanyl)propylamine 3b (according to a known procedure20 with some modifications)\u201d on page 98831, \u20183-(Phenyltellanyl)ethylamine 3a\u2019 should read as \u20182-(Phenyltellanyl)ethylamine 3a\u2019.In the subheading \u201c3-(Phenyltellanyl)ethylamine 3a (M = 248.6)\u201d on page 98831, \u20183-(Phenyltellanyl)ethylamine 3a\u2019 should read as \u20182-(Phenyltellanyl)ethylamine 3a\u2019.In the subheading \u201c3-(Phenyltellanyl)ethylamine 4a, and 3-(phenyltellanyl)propyl isothiocyanate 4b. General procedure\u201d on page 98831, \u20183-(Phenyltellanyl)ethyl isothiocyanate 4a\u2019 should read as \u20182-(Phenyltellanyl)ethyl isothiocyanate 4a\u2019.In the subheading \u201c3-(Phenyltellanyl)ethyl isothiocyanate 6a\u20136f, general procedure\u201d on page 98832, in the sentence reading \u201c2-(Phenyltellanyl)ethyl isothiocyanate  or 2-(phenyltellanyl)propyl isothiocyanate\u201d, \u20182-(phenyltellanyl)propyl isothiocyanate\u2019 should read as \u20183-(phenyltellanyl)propyl isothiocyanate\u2019.Following the subheading \u201cTellurium nitroxides The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "DOI: 10.1039/D1NA00466B.Correction for \u2018Influence of the surrounding medium on the luminescence-based thermometric properties of single Yb The authors regret the omission of two authors, Prof. Rog\u00e9ria R. Gon\u00e7alves and Luiz F. dos Santos, from the original manuscript. The corrected author list is as shown above.In addition the authors acknowledge the financial support from the Brazilian science funding agencies Coordena\u00e7\u00e3o de Aperfei\u00e7oamento Pessoal de N\u00ecvel Superior (CAPES), Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico \u2013 (CNPq) (grant number: 303110/2019-8 and 142199/2020-6 for the scholarship), Minist\u00e9rio da Sa\u00fade (PRONON-SIPAR Project #25000.077093/2015-86), Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo , Funda\u00e7\u00e3o de Amparo \u00e0 Ci\u00eancia e Tecnologia do Estado de Pernambuco (FACEPE) and the National Photonics Institute \u2013 INFo/CNPq.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Retraction: Hui Ren, Guoqin He, Zhiyuan Lu, Qianting He, Shuai Li, Zhexun Huang, Zheng Chen, Congyuan Cao, Anxun Wang, \u201cArecoline induces epithelial\u2010mesenchymal transformation and promotes metastasis of oral cancer by SAA1 expression\u201d, Cancer Science 2021,112 (6), pp. 2173\u20132184.https://onlinelibrary.wiley.com/doi/full/10.1111/cas.14866), has been retracted by agreement between the authors, the journal Editor in Chief, Masanori Hatakeyama, and John Wiley and Sons Australia, Ltd.The above article, published online on 24 February 2021 in Wiley Online Library (The retraction has been agreed following an investigation based on allegations raised by a third party. Several duplicated cell micrographs were found in figures 1, 4, 5 and S4. The authors provided new images and stated that a substantial part of raw data was lost in the meantime. However, concerns about the integrity of the data remain for the newly provided figures. Accordingly, the conclusions of this article are considered invalid."}
{"text": "The main ingredients of proof include a basic hypergeometric summation by George Gasper, the method of creative microscoping (a method recently introduced by the first author in collaboration with Wadim Zudilin), and the Chinese remainder theorem for coprime polynomials.In this paper, three parametric  Han Hamme  numericaq, which we call q-analogues of supercongruences, or simply q-supercongruences , 23q, whces  and n be an integer such that q-supercongruence.Very recently, the present authors  proved tLet q-supercongruence: Let d and r be odd integers satisfying r may be negative) and n be an integer such that q-supercongruence , and d and r are coprime, and Further, the present authors k,by  and /d in , we see -1)/d in , where wves that  is true k in the range q-congruence , and d and r are coprime, and The present authors [Here we point out that  is also is case [ clearly"}
{"text": "Mater. Chem. A, 2019, 7, 20369\u201320382, https://doi.org/10.1039/C9TA07361B.Correction for \u2018Blade coated P3HT:non-fullerene acceptor solar cells: a high-throughput parameter study with a focus on up-scalability\u2019 by Enrique Pascual-San-Jos\u00e9  The authors regret that the labels for IDTBR and IDFBR in A corrected version of The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "The authors have agreed to the retraction."}
{"text": "Journal of Healthcare Engineering has retracted the article titled \u201cHyperleukocytic Acute Leukemia Circulating Exosomes Regulate HSCs and BM-MSCs\u201d [BM-MSCs\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifi"}
{"text": "Alexandre Huat, S\u00e9bastien Thureau, David Pasquier, Isabelle Gardin, Romain Modzelewski, David Gibon, Juliette Thariat and Vincent Gr\u00e9goire were not included as authors in the original publication . The cor"}
{"text": "In"}
{"text": "On page 1, an affiliation is missing from the first and last authors. The affiliations should appear as shown in this erratum.Volume 5, no. 6, e01234-20, 2020, On page 11, in the Acknowledgments section, \u201cBasic Research Fund of Shenzhen City (20170410160041091)\u201d should be revised to \u201cBasic Research Fund of Shenzhen City (JCYJ20170818104557243).\u201d"}
{"text": "In this article the statement in the Funding information section was incorrectly given as \u2018SEOM and SEAP acknowledge the financial support for this project in the form of unrestricted collaboration in the logistics from AstraZeneca\u2019 and should have read \u2018SEOM and SEAP acknowledge the financial support for this project in the form of unrestricted collaboration in the logistics from Merck\u2019."}
{"text": "In the original publication , there wThe authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "Owens  In order to avoid misleading readers, the sentence on page 35448 \u201cThe same clean disposable plastic nozzles have previously been used by Babel and Rudolph,The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "The authors regret that there was a mistake in line 8 of the second paragraph of the right hand column of page 7821 of the original article. The text originally read \u201cindirect band gap was 3.15 eV\u201d. The corrected text should read \u201cindirect band gap was 0.315 eV\u201d.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Retraction Note to: Cardiovascular Toxicology (2021) 21:655\u2013668 10.1007/s12012-021-09657-yThe authors have retracted this article because after publication they found that they were unable to replicate the key results from the cardiomyocyte size experiments. It was also noted that images in Fig.\u00a04B and E had been used in previous publications , 2. Ther"}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors\u2019 attention by a concerned reader that certain of the cell invasion assay data shown in Figs. 2C and 4C were strikingly similar to data appearing in different form in other articles by different authors. Owing to the fact that the contentious data in the above article had already been published elsewhere, or were already under consideration for publication, prior to its submission to"}
{"text": "Due to miscommunication, in the original publication there is a discrepancy in the project number and funding institution, located in Funding Information and Acknowledgement . The corOriginal:Funding: Deputyship for Research & Innovation, Ministry of Education in Saudi Arabia [Grant number IFPRC-146-141-2020].This should be replaced with:Funding: This research work was funded by Institutional Fund Projects under grant No. (IFPDP-39-22).The authors state that the scientific conclusions are unaffected. All co-authors agree with the content of this correction and wish to apologize for any inconvenience caused for the readers resulting from this error."}
{"text": "Open Med. 2021;16(1):1215\u201327. DOI: This article has been retracted due to possible irregularities in the data images presented in results discovered by author. His team is working currently on repeat experiment to investigate any other issues of lack of rigor. In order to avoid confusion about scientific issues, all co-authors requested to withdraw the manuscript."}
{"text": "Snowdon et al., RSC Adv., 2019, 9, 6752\u20136761, DOI: 10.1039/C9RA00034H.Correction for \u2018Comparative study of the extrinsic properties of poly(lactic acid)-based biocomposites filled with talc  The authors regret that the values given for oxygen and water vapor permeability in The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "The authors wish to make the following correction to the original paper :The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. The original publication has been updated."}
{"text": "The journal retracts the 23 February 2018 article cited above.Following publication, concerns were raised regarding the integrity of the images in the published figures. The authors failed to provide a satisfactory explanation during the investigation, which was conducted in accordance with Frontiers\u2019 policies.This retraction was approved by the Chief Editors of Frontiers in Endocrinology and the Chief Executive Editor of Frontiers. The authors agree to this retraction."}
{"text": "Biomol. Chem., 2020, 18, 9018\u20139028, https://doi.org/10.1039/D0OB01912G.Correction for \u2018Tyrosine bioconjugation \u2013 an emergent alternative\u2019 by Peter A. Szijj  The authors regret that there were some errors in the compound numbering shown in o-quinones (e.g. compound 35) produced in the second step can be attacked by nucleophiles\u2019, the sentence \u2018Recently, the suitability of anilines and cyclic amines as nucleophiles was compared, with anilines (e.g. compound 28) exhibiting higher efficiency.51\u2019 should read \u2018Recently, the suitability of anilines and cyclic amines as nucleophiles was compared, with anilines (e.g. compound 38) exhibiting higher efficiency.51\u2019In addition, in the paragraph starting \u2018The The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "In the article titled \u201cEffectiveness of Transcutaneous Electrical Nerve Stimulation with Taping for Stroke Rehabilitation\u201d , the aut\u201cAll authors have read and approved the final version of the manuscript. T.-s.I and J.-h.J are co-first authors. Conceptualization was performed by K.-s.J. and T.-s.I.; writing  was performed by T.-s.I.; writing (review and editing) was performed by K.-s.J. and H.-y.C.; methodology was performed by H.-y.C.; formal analysis was performed by K.-s.J.; investigation was performed by J.-h.J.; measurement visualization was performed by J.-h.J.\u201d"}
{"text": "The authors regret that the original version of our paper unfortunately contained some incorrect representative images. The transwell images of tube formation in Figure The authors confirm that the corrections made in this erratum do not affect the original conclusions. The authors apologize for any inconvenience that the errors may have caused."}
{"text": "There is an error in point 3 of the numbered list in the Previous literature on tax avoidance subsection of the Introduction. The correct statement is: The authors assumed that the intermediate station in a given network route includes only one or two countries . One recent study [20] expanded the scope of its analysis of investment (ownership) structures to three countries and van\u2019t Riet and Lejour [18] expanded it to four intermediate countries. However, in reality, an intermediate station in a tax treaty network can include any number of countries."}
{"text": "However,the wrong labeling of the axes can lead to confusion. Below, an amended The authors regret that"}
{"text": "Nature Communications 10.1038/s41467-022-28533-z, published online 16 February 2022Retraction to: The Authors have retracted this article following discussion with Editors. After publication, the authors Ooi and Perera became aware that data presented in Fig. 3F and Supp Fig. 10 does not correspond to the raw data or patient samples. Further investigation by NUS Research Integrity Office found the data was falsified and fabricated by the first author, Saravanan Gunaseelan. The Integrity Office recommended the authors retract the article.All authors agree to this retraction."}
{"text": "After having been in contact with the authors, they agreed with the decision to retract the paper. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors' attention by a concerned reader that three data panels featured in the flow cytometric plots shown in Figs. 5D and 6D, and several panels from the cell invasion assays shown in Figs. 5C and 6C, were strikingly similar to data appearing in different form in other articles by different authors. Owing to the fact that the contentious data in the above article were already under consideration for publication prior to its submission to"}
{"text": "Sci., 2022, https://doi.org/10.1039/d2bm00844k.Correction for \u2018Inflammatory serum factors from aortic valve stenosis patients modulate sex differences in valvular myofibroblast activation and osteoblast-like differentiation\u2019 by Brandon J. Vogt  The authors regret the incorrect inclusion of an author in the original manuscript. The corrected authorship list is as shown above.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates. It is noted that two similar regions exist between the miR-140-5p inhibitor panel and the miR-140-5p inhibitor+si-Notch1 panel of Figure 7B, as well as the miR-140-5p inhibitor panel and the si-NC panel of Figure S3. Concerns also exist regarding the western blot images in Figures 2, 3, 5, 9, S1 and S5."}
{"text": "In"}
{"text": "Distribution of groundwater pollution to nitrate in GIS environment: A case study of Songhar plain. Journal of Kermanshah University of Medical Sciences (improvement) . 1393 [cited 2021October28]; 18 (3 (76)): 157\u2013164. Available from: The authors regret to say that they have forgotten to cite a key reference for the Table 4 and Fig. 7 during the preparation of draft manuscript. In this regard, the following citation should be considered as the reference for the mentioned sections:The authors would like to apologize for the authors of the above-detailed article any inconvenience caused."}
{"text": "We mourn, and briefly describe the life and contributions of, Andrew H. Wyllie, who was a co-author of the first paper to describe apoptosis, and a primary proponent of the concept. With sorrow we announce the passing of Andrew H Wyllie Fig.\u00a0 on May 2Wyllie later emphasized the characteristics and the importance of apoptosis . In a th"}
{"text": "In our paper"}
{"text": "In the original publication , the refRadiat. Res.2019, 192, 538\u2013561.6. Paulbeck, C.; Griffin, K.; Lee, C.; Cullings, H.; Egbert, S.D.; Funamoto, S.; Sato, T.; Endo, A.; Hertel, N.; Bolch, W.E. Dosimetric Impact of a New Computational Voxel Phantom Series for the Japanese Atomic Bomb Survivors: Pregnant Females. With this correction, the order of references has not been changed. The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "There is an error in"}
{"text": "The authors have re-examined their original data, and have realized that the errors arose as a consequence of inadvertently misfiling and mishandling the data.Following the publication of the above paper, an interested reader drew to the authors attention that, in Oncology Reports for allowing them the opportunity to publish it; furthermore, they apologize for any inconvenience caused to the readership of the Journal.The corrected version of"}
{"text": "Following publication, concerns were raised regarding the validity of the data in the article. The authors failed to provide the raw data or a satisfactory explanation during the investigation, which was conducted in accordance with Frontiers\u2019 policies. Given the concerns, and the lack of raw data, the editors no longer have confidence in the findings presented in the article.This retraction was approved by the Chief Editors of Frontiers in Pharmacology and the Chief Executive Editor of Frontiers. The authors have agreed to the retraction."}
{"text": "In both theTOC and Abstractgraphics and in"}
{"text": "The authors regret that incorrect details were given for ref. 18. The correct version of ref. 18 is given here as ref. The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Cholinergic regulation of hippocampal theta rhythm has been proposed as one of the central mechanisms underlying hippocampal functions including spatial memory encoding. However, cholinergic transmission has been traditionally associated with atropine-sensitive type II hippocampal theta oscillations that occur during alert immobility or in urethane-anesthetized animals. The role of cholinergic regulation of type I theta oscillations in behaving animals is much less clear. Recent studies strongly suggest that both cholinergic muscarinic and nicotinic receptors do actively regulate type I hippocampal theta oscillations and thus provide the cholinergic mechanism for theta-associated hippocampal learning. Septal cholinergic activation can regulate hippocampal circuit and theta expression either through direct septohippocampal cholinergic projections, or through septal glutamatergic and GABAergic neurons, that can precisely entrain hippocampal theta rhythmicity. The hippocampus has been widely accepted as the brain region for memory encoding and short-term memory storage. The hippocampus receives major excitatory inputs from entorhinal cortex and sends the major output back to the entorhinal cortex ,2. The hSeptal cholinergic and GABAergic inputs to the hippocampus have been traditionally deemed as the pacemakers of theta oscillations, providing rhythmic excitatory and inhibitory hippocampal inputs, respectively . HoweverThere is strong evidence supporting cholinergic involvement in not only type II theta but also type I theta. Several studies have observed elevated septal cholinergic firing rate or hippocampal acetylcholine (ACh) release during both type I and type II theta dominant behavioral states ,21,22,23Both hippocampal muscarinic and nicotinic receptors may contribute to theta regulation ,26,27,28Calcium imaging studies showed that calcium activities in dorsal CA1 pyramidal neurons are high during theta states including active exploration and REM sleep, and low during non-theta states including quiet wakefulness and slow wave sleep. Systemic or local hippocampal administrated mAChR antagonist scopolamine significantly reduced calcium activities in pyramidal neurons . Higher MSDB is indispensable for both type I and type II theta generation and has been proposed as the host of theta pacemakers ,47,48. TOther than septal GABAergic neurons, septal glutamatergic neurons can also regulate theta frequency. Rhythmic optogenetic activation of local septal glutamatergic neurons lineally entrained hippocampal type I theta frequency in behaving mice in the 6\u201310 Hz range but had little effect on peak theta power . Septal Although direct optogenetic activation of septal cholinergic neurons only had mild effect on type I theta , septal cholinergic activation can still regulate theta through septal GABAergic and glutamatergic neurons, or through direct septohippocampal cholinergic pathway. Systemic or intraseptal administration of atropine mildly decreased type I theta frequency in freely moving rats ,51. The In addition to theta oscillations, there are gamma oscillations in the hippocampus with a frequency ranging from 25 to 100 Hz . Gamma oRecordings from the CA1 area of freely moving mice show that gamma activity is amplitude-modulated at \u03b8 frequencies. This theta-gamma coupling is stronger during active exploration than during awake immobility. Intraperitoneally administrated atropine increased theta irregularity, reduced gamma power and theta-gamma coupling during explorative behavior . Stronge+ current [The mechanism underlying this cholinergic modulation of theta-gamma coupling is not clear. Studies suggest that hippocampal interneurons are critical for gamma generation. Slow gamma is driven by interneurons that are activated by CA3 inputs, while fast gamma is driven by interneurons activated by medial entorhinal cortical inputs ,74,76,87 current . Gamma a current , suggestSeptal cholinergic neurons are activated during both type II and type I theta states. Cholinergic activation can regulate hippocampal theta through both direct septohippocampal cholinergic pathway and indirect local septal circuit . ElevateLocal septal cholinergic action is essential for type II theta generation but is less important for type I theta and usually only has a moderate effect on type I theta frequency regulation. The relationship between type II theta centered on septal hippocampal loop and type I theta centered on the entorhinal hippocampal loop is currently unclear. Some researchers consider that type II theta coexists with type I theta in behaving animals and is only unmasked by anesthesia administration. It is also possible that each type of theta only occurs during its preferential states. Even if type II and type I theta coexist in behaving animals, it is still not clear if and how they are integrated to modify various aspects of behavior outcomes. Current studies seem to suggest that type II theta is more related to internal drive arising from past experiences, and type I theta is more related to external drive arising from ongoing activities.Cholinergic transmission can target both glutamatergic and GABAergic neurons in MSDB and the hippocampus through both mAChRs and nAChRs. It is currently unclear if septal cholinergic activation directly regulates septal GABAergic neurons or indirectly through local glutamatergic neurons, or both, and what cholinergic receptor subtypes underlie such mechanisms, respectively. An Intersectional Recombinases-mediated Area-and-cell-Specific gene Excision (IRASE) method has recently been developed to achieve receptor knockout with spatial and cell-type specificity . In this"}
{"text": "Journal of Healthcare Engineering has retracted the article titled \u201cControlled Hypotension Combined with Femoral Nerve Block for Knee Replacement without Tourniquet\u201d [rniquet\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifi"}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a satisfactory reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors\u2019 attention by a concerned reader that certain of the data shown for the cell migration and invasion assays in Figs. 2C and 5C were strikingly similar to data appearing in different form in other articles by different authors. Owing to the fact that the contentious data in the above article had already been published elsewhere, or were already under consideration for publication, prior to its submission to"}
{"text": "The authors regret that an incorrect grant number was shown in the Acknowledgements section of the published article. The corrected section should read:We acknowledge financial support from the General Directorate of Research Grants, \u0623\u062a-34-405, from King Abdul-Aziz City of Science and Technology (KACST), Kingdom of Saudi Arabia.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "The authors would like to correct The authors apologise for this error."}
{"text": "The authors have provided the original correct data for 0.03 MPa.The Royal Society of Chemistry has asked the affiliated institution (Tianjin University) to investigate this matter and confirm the integrity and reliability of the new data and figures provided.An expression of concern will continue to be associated with this manuscript until we receive information from the institution on this matter.Laura Fisher10th November 2022RSC AdvancesExecutive Editor,"}
{"text": "He had no systemic or B symptoms. The physical examination showed a violaceus lesion soft in consistency on the left leg Figures\u00a0 and\u00a02. Ms Figure\u00a0. The nexThe authors report no conflict of interest.All authors wrote and edited the manuscript. The patient provided written informed consent for the publication of this Clinical Picture."}
{"text": "The authors wish to make the following corrections to this paper :After the publication of the manuscript, the authors recognized that one reference in the discussion session (in the main text) was wrong and should be replaced with a new one. The changes are provided below. Furthermore, Potts et al. [58] in a recent work reported differences in hydrocarbons removal between shallow and deep sediment consortia , highlighting the role of consortium origin.FEMS Microbiol. Ecol.2018, 94, 127.58.\u2003Potts, L.D.; Calderon, L.J.P.; Gontikaki, E.; Keith, L.; Gubry-Rangin, C.; Anderson, J.; Witte, U. Effect of spatial origin and hydrocarbon composition on bacterial consortia community structure and hydrocarbon biodegradation rates. The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. The original publication has also been updated."}
{"text": "BCR-ABL negative myeloproliferative neoplasm that usually affects older adults with a poor prognosis. Leukemia cutis is an extramedullary manifestation of leukemia and may be misdiagnosed by dermatologists. Here, we describe a case of CNL in a 6-year-old Chinese girl with leukemia cutis as the first manifestation. Her skin rashes failed to attract the attention of dermatologists in early stages. The diagnosis was confirmed by peripheral smear, bone marrow studies, genomic analysis and skin biopsy.Chronic neutrophilic leukemia (CNL) is a rare  BCR-ABL negative myeloproliferative neoplasm that is characterized by neutrophilia, splenomegaly, and poor prognosis (CSF3R) gene have been identified in most cases of CNL (Chronic neutrophilic leukemia (CNL) is a rare rognosis . CNL usurognosis . Activatnosis CSFR gene has of CNL . Leukemis of CNL . Here, w9/L, neutrophils: 87.3%, lymphocytes: 9.1%, monocytes: 0.9%, eosinophils: 0.3%, basophils: 2.4%, red blood cells: 3.01 \u00d7 1012/L, hemoglobin: 99 g/L, and platelet count: 190 \u00d7 109/L. The peripheral smear revealed a predominance of mature neutrophils with rare blasts (1%). Bone marrow studies revealed hypercellular marrow with granulocytic hyperplasia  and minor(s)\u2019 legal guardian/next of kin, for the publication of any potentially identifiable images or data included in this article.RW and JY were responsible for the diagnosis and treatment of the patient. YZ and JY prepared the manuscript. RW and ZX participated in the revision of the manuscript. All authors contributed to the article and approved the submitted version."}
{"text": "This should have been 3J70.The authors regret that they incorrectly quoted the structure template reference as Therefore, the authors would like to make the following corrections:http://www.rcsb.org) with accession IDs are 5FYK12 and 5FUU13 at 3.11 \u00c5 and 4.19 \u00c5 resolution, respectively.\u201d This should read \u201cProtein Data Bank  with accession IDs 5FYK12 and 3J70 at 3.11 \u00c5 and 20 \u00c5 resolution, respectively.\u201dThe first sentence of Section 2.1 currently contains the text \u201cProtein Data Bank  Ribbon representation of the closed and open gp120 with PDB IDs of 5FYK and 3J70, respectively.\u201dThe caption for Fig. 1 currently contains the text \u201cThe structural models of gp120. (A and B) Ribbon representation of the closed and open gp120 with PDB IDs of Ref. 13 should not have been included in the reference list as it corresponds to the incorrect structure template reference.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "The authors regret that the data availability statement was not correctly given in the original article. The correct statement is as shown below.10.15125/BATH-01212.Data supporting this work is freely accessible in the University of Bath research data archive at DOI: The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "The authors have retracted this article. Following publication, errors were identified affecting Figs.\u00a04 and 6. The values of mean total chlorophyll concentration in control plants and individual leaves  reported in the article were several fold higher than those from other reports. Moreover, the chlorophyll a/b ratios of control plants presented in Fig.\u00a04c were also much higher than reported values for tree seedlings. The authors believe these discrepancies are due to technical errors and intend to submit a revised manuscript which will undergo peer review. All authors agree with this retraction."}
{"text": "Brassica oleracea var. sabellica) as miracle food with special reference to therapeutic and nutraceuticals perspective\u201d, by Waseem Khalid, Muhammad Sajid Arshad, Muhammad Imran, Rabia Shabir Ahmad, Ali Imran, Tahira Batool Qaisrani, Zubia Asghar, Adnan Husain, Faqir Muhammad Anjum, Hafiz Ansar Rasul Suleria, Food Science & Nutrition, 2022. The above article, published online on 5 November2021 in EarlyView section on Wiley Online Library (https://doi.org/10.1002/fsn3.2476), has been retracted by agreement between the authors, the journal\u2019s Editor\u2010in\u2010Chief, Prof. Y. Martin Lo, and Wiley Periodicals, LLC. The retraction has been agreed as the editorial office found unambiguous evidence that the manuscript was accepted solely based on compromised reviewer reports.Retraction: \u201cKale ("}
{"text": "The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates. Some of the western blot bands for Figure 5C, specifically the Cyclin/BT474 bands, appear to be highly similar to the Figure 5C B-Carwnin/HO-8910 bands in a paper by Cheng et al. 2015 (doi: 10.18632/oncotarget.4541), which has no related authors."}
{"text": "The Publisher retracts the cited article.Following publication, the publisher uncovered evidence that false identities were used in the peer-review process. The assignment of a fake reviewer was confirmed by an investigation, conducted in accordance with Frontiers\u2019 policies and the Committee on Publication Ethics (COPE) guidelines.The investigation also uncovered concerns about the presentation and validity of the data in the article that normally would have led to a rejection. When contacted, the authors failed to provide a data set that adequately supports the reported conclusions.The authors do not agree to this retraction.This retraction was approved by the Chief Editors of Frontiers in Physiology and the Chief Executive Editor of Frontiers."}
{"text": "The authors regret that an incorrect grant number was shown in the acknowledgements section of the published article. The corrected section should read:This work was financially supported by the National Natural Science Foundation of China (No. 21663020) and Special talent start-up project of Ningxia Medical University (XT2020017).The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Necrotizing esophagitis is rare and poorly understood. The etiologies reported in what little has been published  seem somewhat simplistic and lack any direct evidence. The following paper illustrates a recent clinical case while laying out arguments supporting esophageal spasm as a possible contributing factor. The images depict a case of necrotizing esophagitis in a 32-year-old man having ingested cocaine  and 2. NOn the other hand, animal studies have shown that esophageal spasm can increase luminal pressures sufficiently to cause ischemia of the esophageal wall . EsophagThe authors certify that this manuscript represents original work, that they have the rights in the work, and that it is not being considered for publication elsewhere and has not already been published elsewhere.All authors participated fully in drafting of the manuscript. All authors have read and approved submission."}
{"text": "The authors would like to correct their conflict of interest declaration. It should read: Dr. Emery N. Brown declares he is a cofounder of PASCALL Systems, which is a startup for a next generation wearable brain monitoring system for patient care. The other authors declare no conflicts of interest."}
{"text": "Dear Editor,we would like to share ideas on the publication \u201cPrevalence of COVID-19 Vaccine Side Effects among Early-Vaccinated Healthcare Workers in Eastern Ethiopia . Another"}
{"text": "The authors were able to consult their original data files, and realized that these figures had indeed been assembled incorrectly; subsequently, they requested that a corrigendum be published to take account of the errors that were made during the compilation of these figures.Oncology Reports has considered the authors' request to publish a corrigendum, but has decided to decline this request on account of the large number of errors that have been identified; rather, the article is to be be retracted from the Journal on the basis of an overall lack of confidence in the presented data. The Editor apologizes to the readership of the Journal for any inconvenience caused.Having investigated this matter in the Editorial Office, however, additional panels of overlapping data were identified, comparing between Figs. 3 and 5; specifically, overlapping data panels were also identified in panels in Figs. 3C, E and F, and 5C and D. The Editor of"}
{"text": "The authors wish to make the following corrections to this paper :Remove Figure 3 and update References 167 and 168.J. Sports Sci. in press.\u201d\u201c167. Johnson, D.; Cumming, S.; Bradley, B.; Williams, S. The Influence of Exposure, Growth and Maturation on Injury Risk in Academy Football Players. \u201c168. Johnson, D.; Cumming, S.; Bradley, B.; Sheree, B.; Williams, S. Can We Reduce Injury Risk during the Growth Spurt? An Iterative Sequence of Prevention in Male Academy Footballers. Ph.D. Thesis, Training Load in Adolescent Footballers, University of Bath, Bath, UK. in press.\u201dThe corrected references appear below:Figure 3 has been removed.https://www.researchgate.net/publication/340175460_David_Johnson_Sports_Kongress_Poster_2020 (accessed on 1 September 2021).\u201d\u201c167. Johnson, D.M.; Williams, S.; Bradley, B.; Cumming, S. The Interaction between Training Volume, Growth, Maturation, and Injury Risk in Adolescent Football Players. Paper Presented at: Sport Kongress 2020; 30 January 2020. Available online: https://www.youtube.com/watch?t=1291&v=wDE8lyYfZ64&feature=youtu.be (accessed on 1 September 2021).\u201d\u201c168. Johnson, D.M.; Williams, S.; Bradley, B.; Cumming, S. Growth, Maturation and Bio-Banding in Football. Paper Presented at: Webinarium Elitprojektet Online; 16 April 2021. Available online: The authors would like to apologize for any inconvenience caused to the readers by these changes."}
{"text": "Computational and Mathematical Methods in Medicine has retracted the article titled \u201cEpidemiological Features of COVID-19 in Makkah City: A Retrospective Data Analysis\u201d [Following an investigation conducted by the Hindawi Research Integrity team , signifiThe authors do not agree to the retraction."}
{"text": "The authors regret that the TEM image and the values from the distribution histogram of nanoparticles were incorrectly shown in The corrected version of The authors also regret that there was an error in the first sentence below Fig. 1 of the original article. The text originally read: TEM images of DOX\u2013AuGCs display a spherical shape and a narrow dispersion of the nanoparticle size with an average diameter of 50 \u00b1 3 nm .This sentence should read: TEM images of DOX\u2013AuGCs display a spherical shape and a relatively narrow dispersion of the nanoparticle size with an average diameter of 50 \u00b1 30 nm .The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Erratum zu:Herzschr Elektrophys 202210.1007/s00399-022-00854-yIn der Originalversion des Beitrags stand der Hinweis zu Teil\u00a01 im Untertitel. Dieser Hinweis wurde nun in den Haupttitel eingef\u00fcgt.Der Originalbeitrag wurde korrigiert."}
{"text": "In Fig.\u00a02Volume 11, no. 5, e02536-20, 2020,"}
{"text": "Several errors were introduced after proofreading, and the authors hence wish to make the following corrections to this paper :In the original publication, there was a mistake in the legend for Figure 1. The figure note \u201c* Weighted measure. ** Weighted or unweighted measure.\u201d was redundant as this information is included in Figure 1. The corrected legend is shown below.Figure 1. Overview of summary measures of health inequality.In the original publication, there was a mistake in Tables A7 and A9. Several numbers in the tables were missing a decimal. The corrected Tables A7 and A9 are shown below. There was an error in the original publication. There were several formatting errors in Section 3. Summary Measures of Health Inequality, including sub-section headers should have been italic; summary measure names (headers) should have been bold; headers for \u201cDefinition\u201d, \u201cCalculation\u201d and \u201cInterpretation\u201d should not have been numbered; text for \u201cDefinition\u201d, \u201cCalculation\u201d and \u201cInterpretation\u201d should not have been italic. A correction has been made to 3. Summary Measures of Health Inequality. Please refer to the publication for the corrected text.The authors apologize for any inconvenience caused and wish to state that the scientific conclusions are unaffected. The original publication has also been updated."}
{"text": "Nature Communications 10.1038/s41467-021-27698-3, published online 10 January 2022.Correction to: In Supplementary Fig.\u00a0In the caption of Supplementary Fig.\u00a0In the caption of Supplementary Fig.\u00a0In the caption of Supplementary Fig.\u00a0The HTML has been updated to include a corrected version of the\u00a0Updated Supplementary Information"}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a satisfactory reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors' attention by a concerned reader that certain of the Transwell migration assay data shown in Fig. 3A were strikingly similar to data appearing in different form in other articles by different authors. Owing to the fact that the contentious data in the above article were already under consideration for publication prior to its submission to"}
{"text": "The authors regret that an incorrect grant number was shown in the acknowledgements section of the published article. The corrected section should read:This work was supported by the National Natural Science Foundation of China [31870201] and the Overseas Cooperation Project of Jilin Province [20200801069GH]. This work was performed at the High Performance Computing Center of Jilin University.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Phil. Trans. R. Soc. B377, 20200493. (Published 7 March 2022) (doi:10.1098/rstb.2020.0493)The originally published version of this paper used the term \u2018North Vietnam\u2019 to refer to northern Vietnam and not the former Democratic Republic of Vietnam. For clarity, this term has been changed to \u2018northern Vietnam\u2019."}
{"text": "BMC Psychology (2023) 11:2110.1186/s40359-023-01052-2Following publication of the original article [1], the authors flagged that a 'model consent form\u2019 completed in the Dutch language had been erroneously added to Figure 2. The figure has since been corrected to remove the form. The authors thank you for reading this correction and apologize for any inconvenience caused."}
{"text": "The authors regret that in the original version of the manuscript the affiliations of Jang Ho Kim and Ki Taek Lim were reversed. The correct affiliations are presented in this correction notice.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "The authors would like to correct this error and apologize for any inconvenience it may have caused. The correct format of the authors\u2019 list is as follows:In the published article \u201cConstruction and effect evaluation of different sciatic nerve injury models in rats\u201d (Siwei Qu, Ning Ma, Weixin Wang, Sen Chen, Qi Wu, Yangqun Li, Zhe Yang"}
{"text": "Retraction Note: J Ovarian Res 13, 13 (2020)https://doi.org/10.1186/s13048-020-0611-4The Editors-in-Chief have retracted this article. After publication, concerns were raised regarding similarities between the western blot Figs. 5c and 6b) and flow cytometry  data presented in this article and a number of other articles by different authors that were under consideration in different journals within a similar time frame \u20135. Furthc and 6b The Editors-in-Chief therefore no longer have confidence in the presented data.Zhengfang Xiong, Bing Li, Wenjuan Wang, Xianghui Zeng, Binye Li and Liyun Wang agree to this retraction. Shengyan Jian has not responded to any correspondence from the editor or publisher about this retraction."}
{"text": "The authors declare that these corrections do not change the results or conclusions of this paper. The authors have provided the corrected version of Figs. 2 and 3 here. The authors also would like to correct the description of statistics in the Methodology Statistics section as \u201cThe results are expressed as the mean value\u2009\u00b1\u2009SEM and were interpreted by the The revised Fig."}
{"text": "Phil. Trans. R. Soc. B377, 20210025. (Published online 24 January 2022) (https://doi.org/10.1098/rstb.2021.0025)After publication, the authors identified errors in two panels of b), the legend for the relative read abundances of COI and 18S markers previously showed values for the incorrect marker, with the values shown for COI (green) showing those for 18S (purple) and vice versa.In panel (Clavelina lepadiformis (panel (d)) showed a gradual increase from 1950 to 2000; however, the species was first recorded in 2000. Additionally, the plots for Microcosmus squamiger and Styela plicata were incorrectly switched.Owing to an error in plotting, the historic range of None of the above errors affected the conclusions or analyses in the study.This has been corrected on the publisher's website."}
{"text": "Journal of Healthcare Engineering has retracted the article titled \u201cCandidate Genes of Allergic Dermatitis Are Associated with Immune Response\u201d [esponse\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifiThe authors agree to the retraction."}
{"text": "The authors would like to correct errors in their prior publication . In the The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected."}
{"text": "Journal of Healthcare Engineering has retracted the article titled \u201cIopromide and Iodixanol in the Development of Postoperative Contrast Nephropathy in Patients with Renal Insufficiency: A Meta-Analysis\u201d [nalysis\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifiThe authors do not agree to the retraction."}
{"text": "In Fig.\u00a02I, there are partial duplications in the N-GSDMD_1-242 and N-GSDMD_1-252 panels and the N-GSDMD_1-252 and N-GSDMD_1-262 panelsVolume 13, no. 1, e03600-21, 2022, Due to the large number of original pictures, when processing the data, the authors inadvertently placed the results of different angles of N-GSDMD_1-242 to the positions of N-GSDMD_1-252 and N-GSDMD_1-262 by mistake. Figure\u00a02I has been updated with the correct images, as shown below. The authors apologize for the error and state that the error does not change the scientific conclusions of the article in any way."}
{"text": "There was an error in the original publication . The des2. Subjects and Methods, 2.2. Characteristics Measured, 1st Paragraph, lines 2\u20137:A correction was applied to Fecal samples were collected within 3 days prior to the study by using a commercial tube kit , and stored at 4 \u00b0C until the DNA was extracted, as previously reported . The gut microbiota composition was investigated by conducting a next-generation sequencing analysis targeting the V3\u2013V4 region of the prokaryotic 16S rRNA genes, as previously described [23].The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "Authors regret that the original version of our paper unfortunately contained some incorrect representative images in Figure Authors confirm that the corrections made in this erratum do not affect the original conclusions. We apologize for any inconvenience that the errors may have caused."}
{"text": "Signal Transduction and Targeted Therapy 10.1038/s41392-021-00739-5, published online 03 December 2021Correction to: 1, the author found two images in the supplement materials were used incorrectly. Additionally, there is an error in the chemical structure of Aiphanol in Figs. After online publication of the letterSupplemental materialsSupplementary Fig S1cSupplementary Fig S4b"}
{"text": "In a previous study, C57BL/6J mice were considered to resist 5/6 nephrectomy\u2010induced CKD, which was presented as no hypertension, less glomerular damage, and renal fibrosis even 16\u00a0weeks after 5/6 nephrectomy; instead, 129S3 and CD\u20101 (ICR) mice exhibited prominent CKD after 5/6 nephrectomy.et al.It is curious that Kawao Despite our doubts, we were so impressed that the conception of the study conducted by the authors may provide a potential therapeutic strategy to treat the CKD\u2010mineral bone disorder and sarcopenia in CKD patients.The authors declare that they have no conflict of interests."}
{"text": "Bioscience Reports at the request of the Editor-in-Chief and the Editorial Board following receipt of a notification from a reader, alerting the Editorial Board to multiple similarities between figures of this manuscript with those of other articles. The Figure 4B invasion/siFEZF1-AS1 panel and the Migration/NC panel show similarities with panels from Fig.3B and 5C from Li et al. 2019 (doi: 10.1042/BSR20181882), and the Figure 4A 0h/NC panel shows similarities with a panel from Fig. 7F of Li et al. 2021 (doi: 10.18632/aging.202847). The authors have been contacted with regards to the retraction and have not responded to the Journal's queries or the concerns raised. Given the extent of the issues raised, the Editorial Board stand by the decision to retract the article.This article is being retracted from"}
{"text": "U.S. Medicare covers many palliative services; however, Iowa\u2019s rurality and high rate of older adults (OAs) aged 65 or over make it unclear whether older Iowans have equitable service access. Hospital-based palliative care services (HBPCSs) include curative treatment, whereas other providers of palliative care may not. Thus, this study only examined OAs\u2019 geographic access to HBPCSs in Iowa.This study used the American Hospital Association and U.S. Census Bureau estimate in 2017. The geographical distribution of hospitals and HBPCSs was examined using a county-level approach, considering rural/urban status (using the Office of Management and Budget\u2019s definitions) and OA population proportion.Of the 99 counties in Iowa, 89 were rural. Of the 116 hospitals statewide, one urban county and nine rural counties had no hospital. A total of 52 hospitals provided HBPCSs in 43 counties across nine urban and 34 rural counties. HBPCSs were primarily located in central Iowa, with northern and southern Iowa having the lowest access to HBPCSs. The OA population ratio was higher in counties without HBPCSs (19%) than HBPCSs (15.7%). All 54 counties with over a 20% OA population were concentrated in rural counties, while only 37% of these rural counties had HBPCSs.This study suggests a regional imbalance of HBPCS providers for OAs in Iowa. Results showed that rural communities with a high ratio of OAs lack HBPCSs and suggest HBPCSs should be expanded at hospitals in northern and southern Iowa counties where many OAs live."}
{"text": "The authors regret that the following funding information was omitted from the Acknowledgements section of the original article.Funding for this research was provided by: Association Nationale de la Recherche et de la Technologie (CIFRE No. 2018/1314).The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "The consequences of schizophrenia stigma are numerous and highly damaging to individuals, their families, the health care system and society. Mental health professionals (MHP) are considered to be one of the main sources of schizophrenia stigmatization.The aim of the study was to identify individual and contextual factors associated with stigmatization in MHP in its three dimensions.An online survey was conducted with specific measures of MHP stigmatization . Four categories of potential associated factors were also measured: sociodemographic information, contextual characteristics (e.g. work setting), individual characteristics  and theoretical beliefs . Models of prediction were computed when applicable.Responses of 357 MHP were analysed. The main factors associated with stigmatization  in MHP are of two types: i) individual beliefs  and ii) characteristics of practices .These original results suggest new strategies for reducing stigma in mental health practices such as focusing on individual beliefs and fostering recovery-oriented practice and professional utility beliefs.No significant relationships."}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors\u2019 attention by a concerned reader that certain of the cell migration and invasion assay data shown in Fig. 5D were strikingly similar to data appearing in different form in other articles by different authors. Owing to the fact that the contentious data in the above article had already been published elsewhere, or were already under consideration for publication, prior to its submission to"}
{"text": "In the original publication , the BasThe authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "ICEID is organized by the Centers for Disease Control and Prevention and Task Force for Global Health, Inc.Emerging Infectious Diseases is providing access to these abstracts on behalf of the ICEID 2022 program committee (Emerging Infectious Diseases has not edited or proofread these materials and is not responsible for inaccuracies or omissions. All information is subject to change. Comments and corrections should be brought to the attention of the authors."}
{"text": "Journal of Healthcare Engineering has retracted the article titled \u201cInfluence of Virtual Reality Technology on Clinical Thinking Cultivation of Medical Students\u201d [tudents\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifi"}
{"text": "The corrected **** appears below. The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated.In the original publication , there w"}
{"text": "The authors regret that there were two errors in the original article. In the \u201cExperimental details\u201d section on page 115205, \u201c1 M sodium sulfide at 70\u201380 \u00b0C for 24 h\u201d should have read \u201c0.5 M sodium sulfide at 70\u201380 \u00b0C for 24 h\u201d. Additionally, The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Seabuckthorn silver nanoparticles (SBT@AgNPs) featuring high stability and longevity, antibacterial, antioxidant potential: a nano disinfectant future perspective\u2019 by Thiyagarajan Kalaiyarasan et al., RSC Adv., 2017, 7, 51130\u201351141, DOI: 10.1039/c7ra10262c.Correction for \u2018One pot green preparation of  The authors regret that an incorrect versions of The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "In the original publication , the funCorrected Funding:This research was funded by S\u00e3o Paulo State Research Support Foundation FAPESP, Grant Number 2019/03415-3, and Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior\u2014Brasil (CAPES), Finance Code 001.The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "Retraction Note: BMC Neurosci19, 7 (2018).10.1186/s12868-018-0406-3The Editor has retracted this article at the corresponding author\u2019s request. After publication, concerns were raised regarding similarities in the presented data. Specifically:In Fig.\u00a06, the PFC 5xFAD\u2009+\u2009SLCP (2d) and CA1 5xFAD\u2009+\u2009Cur (2d) images appear highly similar;Also in Fig.\u00a06, the CA3 5xFAD\u2009+\u2009Cur (2d) and 5xFAD\u2009+\u2009SLCP (2d) appear to originate from the same sample;Figure\u00a08a GFAP 5xFAD (top) appears highly similar to Fig.\u00a013a GFAP 5xFAD (bottom) with a brightness adjustment.The authors checked their data and identified additional errors:In Fig.\u00a011a, the two Iba-1 5xFAD images originated from the same sample;In Fig.\u00a014a, the two Iba-1 5xFAD images originated from the same sample.The Editor and the authors therefore no longer have confidence in the presented data.All authors agree to this retraction.BMC Neurosci19, 7 (2018). 10.1186/s12868-018-0406-3.[1] Maiti, P., Paladugu, L. & Dunbar, G.L. Solid lipid curcumin particles provide greater anti-amyloid, anti-inflammatory and neuroprotective effects than curcumin in the 5xFAD mouse model of Alzheimer\u2019s disease."}
{"text": "Computational and Mathematical Methods in Medicine has retracted the article titled \u201cInvestigation of Influencing Factors on the Prevalence of Retinopathy in Diabetic Patients Based on Medical Big Data\u201d [ig Data\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifiThe authors do not agree to the retraction."}
{"text": "In the Acknowledgements section, the attribution \u201cthe Czech Republic from ERDF \u201cInstitute of Environmental Technology \u2013 Excellent Research\u201d (No. CZ.02.1.01/0.0/0.0/15_019/0000853), should read \u201cthe Czech Republic from ERDF OP RDE project No. CZ.02.1.01/0.0/0.0/16_019/0000853\u201d.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "There was an error in the original publication . The funFundingThis work was funded by the Deanship of Scientific Research (DSR), King Abdulaziz University, Jeddah, under grant No. (G: 405-135-1443). The authors, therefore, gratefully acknowledge the technical and financial support from the DSR. Additionally, the authors were supported by the Engineering Mathematics and Physics Department, Faculty of Engineering and Technology, Future University in Egypt, New Cairo 11845, Egypt.FundingThis work was funded by the Deanship of Scientific Research (DSR), King Abdulaziz University, Jeddah, under grant No. (G: 405-135-1443). The authors, therefore, gratefully acknowledge the technical and financial support from the DSR. AcknowledgmentAdditionally, the authors were supported by the Engineering Mathematics and Physics Department, Faculty of Engineering and Technology, Future University in Egypt, New Cairo 11845, Egypt.The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "Due to a production error, there was a mistake in"}
{"text": "DOI: 10.1039/D0RA04898D.Correction for \u2018Sustainable waste management and recycling of Zn\u2013Al layered double hydroxide after adsorption of levofloxacin as a safe anti-inflammatory nanomaterial\u2019 by Samar M. Mahgoub  The authors regret that, in the originally published version of this article, the name of the author Fatma I. Abo El-Ela was incorrectly displayed as Fatma L. Abo El-Ela. The correct author list is displayed above.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "In the published manuscript  in the RThe authors apologize for any inconvenience. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "Consequently, the article has been retracted with the agreement of the Editorial Board.The authors agree with this retraction."}
{"text": "Computational and Mathematical Methods in Medicine has retracted the article titled \u201cApplication of Molecular Techniques for Assessment of SOX2 and miR126 Expression as Prognostic Markers in Esophageal Carcinoma\u201d [Following an investigation conducted by the Hindawi Research Integrity team , signifiThe authors do not agree to the retraction."}
{"text": "Journal of Healthcare Engineering has retracted the article titled \u201cPreparation of Drug Sustained-Release Scaffold with De-Epithelized Human Amniotic Epithelial Cells and Thiolated Chitosan Nanocarriers and Its Repair Effect on Spinal Cord Injury\u201d [ Injury\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifiThe authors do not agree to the retraction."}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors\u2019 attention by a concerned reader that certain of the cell migration and invasion assay data shown in Figs. 2C, 4C and 5C were strikingly similar to data appearing in different form in other articles by different authors. Owing to the fact that the contentious data in the above article had already been published elsewhere, or were already under consideration for publication, prior to its submission to"}
{"text": "The authors regret that a funder was omitted that should have been acknowledged. This acknowledgement is as follows:This research was supported by the Ministry of Education of Republic of Korea and the National Research Foundation of Korea (NRF-2019R1G1A1005342).The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Gemma Battagliese was not included as an author in the original publication [lication . The corAuthor Contributions: M.P.M., G.B., A.D., R.C., L.T., M.F., F.P., M.F., G.F., M.V. and M.C.: Protocol/project development-Data analysis; M.P.M., G.B., A.D., F.P., R.C., L.T.: Data collection or management; M.C., G.B., G.F., A.D. and M.F.: Subtle Data Analysis; M.F., G.B., M.C. and A.D.: Manuscript writing. All authors read and approved the final version of the manuscript.1. We have deleted the original affiliation 3 and added Gemma Battagliese\u2019s affiliation \u201cCentro di Riferimento Alcologico della Regione Lazio, Mental Health Department, ASL Roma 1, 00185 Rome, Italy\u201d.2. The right postcode of affiliation 7 is 60122.The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. The original publication has also been updated."}
{"text": "H-1,2,4-triazol-1-yl)-NNO-azoxy]furazans: energetic materials containing an N(O)N\u2013N fragment\u2019 by Dmitry A. Gulyaev et al., RSC Adv., 2021, 11, 24013\u201324021, DOI: 10.1039/D1RA03919A.Correction for \u2018[(3-Nitro-1 The corrected formula should read as \u201ci\u201d.In the original article, in Table 2 the formula \u201cThe Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "However, because of the comparison with the methods represented by colored lines, replacing this figure does not affect to the substantive meaning of the results obtained, including our conclusion, or anything other than the revised sentences.The authors wish to make the following correction to this paper . There w"}
{"text": "Retraction Note: BMC Public Health 20, 1657 (2020)https://doi.org/10.1186/s12889-020-09765-4The Editor has retracted this article. After publication, concerns were raised regarding the data analysis and conclusions in the paper. The authors have provided raw data, and post-publication review found inconsistencies in methodology and major misinterpretation of the primary result. None of the authors agree to this retraction."}
{"text": "An ensemble of 29 wheat crop models simulates seasonal wheat growth well under locally recommended sowing conditions, but needs improvements to capture the yield response to early sowing, especially under high sowing density. Crop multi-model ensembles (MME) have proven to be effective in increasing the accuracy of simulations in modelling experiments. However, the ability of MME to capture crop responses to changes in sowing dates and densities has not yet been investigated. These management interventions are some of the main levers for adapting cropping systems to climate change. Here, we explore the performance of a MME of 29 wheat crop models to predict the effect of changing sowing dates and rates on yield and yield components, on two sites located in a high-yielding environment in New Zealand. The experiment was conducted for 6 years and provided 50 combinations of sowing date, sowing density and growing season. We show that the MME simulates seasonal growth of wheat well under standard sowing conditions, but fails under early sowing and high sowing rates. The comparison between observed and simulated in-season fraction of intercepted photosynthetically active radiation (FIPAR) for early sown wheat shows that the MME does not capture the decrease of crop above ground biomass during winter months due to senescence. Models need to better account for tiller competition for light, nutrients, and water during vegetative growth, and early tiller senescence and tiller mortality, which are exacerbated by early sowing, high sowing densities, and warmer winter temperatures. Wheat is the most traded crop commodity at the global scale and provides more than 20% of calories and protein in human diets . For decAdapting sowing conditions to climate change requires an understanding of how crop growth and yield development are affected by sowing date and density. Increased temperature shortens the growing season of wheat and shifts optimal sowing dates . The abiProcess-based crop growth models were developed to study the multiple interacting factors affecting crop growth, development, and yield formation under field conditions  are used to simulate the effect of climate variability and change on cropping systems  and Wakanui  in the Canterbury Region of the South Island of New Zealand . \u2018Wakanu\u22122, while at Wakanui, only the locally recommended sowing density was used (150 seeds m\u22122).In the Canterbury region of New Zealand, winter wheat is usually sown between early April and mid-May, with some farmers sowing in late March in recent years . At LeesThe objective of the Leeston trials was to increase wheat production in a high yielding environment without water and nitrogen stress. The trials investigated the complex interaction between tiller development, ear population, and grain yield, with the goal of finding the optimal sowing density for an early sowing date. The experiments consisted of a split-plot design with sowing dates as the main plots and sowing rates as the subplots, with four replicates. The Wakanui trials used a single sowing density and investigated different cultivars, sowing dates, and the use of plant growth regulators (2015\u20132016) or defoliation (2016\u20132017 and 2017\u20132018), at different sowing dates. The experiments were designed as randomized blocks with sowing dates as the main plots and cultivar by plant growth regulation or defoliation as the subplots, replicated four times. In our study, we considered only the data of the \u2018Wakanui\u2019 cultivar grown under standard growth regulation and without defoliation.\u22121 and irrigation up to 210 mm of water.The field management was adapted each year to obtain ideal growth conditions: crops received a yearly N fertilization of between 122 and 284 kg N haIndividual plots (12 m\u00d71.65 m) were drilled into a top worked seed bed. At both sites, the soil type was Temuka clay loam (Fluventic Endoaquents in the USDA classification), a deep, low permeability soil with high plant available water capacity  participated in this study and contributed to the MME output  Wheat group  anthesis (Zadoks 65) and physiological maturity (Zadoks 87). In addition, the grain, stem, chaff, and leaf dry weight at maturity, ear number and grain number, grain unit dry weight, and harvest index were provided. Also, time series of measurements of total above ground dry biomass, leaf number per stem, and LAI were provided, as well as NDVI and FIPAR.After calibration, simulations were conducted by each model for all combinations of sowing date, sowing density, and growing season , for a tGY) to the mean , was quantified with the coefficient of variation (CV), which is the ratio of the standard deviation  and the simulated (S) values and is given as:The root mean square error (RMSE) is the standard deviation of the residuals and is calculated as the squared root of the mean squared difference between the observed (The model accuracy was quantified using the relative RMSE (RRMSE), expressed as a percentage, which is useful to compare outputs with different units. RRMSE is obtained by dividing RMSE by the mean of the observations  was performed to test if year, sowing date, and sowing rate had significant main or interaction effects on grain yield. We considered only the Leeston trials, where both sowing date and rate were tested . The anaP>0.05) but the ANOVA showed a significant variation of measured grain yield with year (P<0.001) and sowing date (P<0.01). The sowing density had no significant effect on measured grain yield , the MME performance was good for simulating the in-season development of the total above ground biomass, LAI and FIPAR, as well as the final grain yield measured in the field  to excellent (RRMSE of 5.75 for harvest index) ; Fig. 2.The simulated interannual variability of grain yield increased with increasing RRMSE , meaning\u22122 in the simulations, while in the measurements we observed a slight decrease between 150 and 200 seeds m\u22122. Conversely, average grain dry mass and harvest index showed little change with sowing density , under earlier sowing the final total above ground biomass and grain yield increased for both measurements and MME simulations , the effect of sowing date on final above ground biomass and grain yield initially showed a decrease between February and early March sowing and then an increase  the decrease of NDVI and FIPAR during winter was also observed for March sowings, highlighting that the decrease could be observed in later sowings , final total above ground biomass and grain yield increased with earlier sowing (\u22122), early sowing increased tillering, and thus increased competition and tiller mortality  simulated a decrease in FIPAR after the rapid increase with the February sowing in 2015 and only two  with the February sowing in 2014, while none of the models simulated the decrease measured with the March sowing in 2014. Interestingly, the models that were more successful in simulating the FIPAR response represent different modelling approaches, SQ being a very sophisticated model that represents tillering, grain number, and size explicitly, while HE is based on a one-leaf and one-grain approach. Furthermore, the models that captured the decrease in FIPAR did not show better performance in simulating yield . This shThe comparison of the MME and experimental data highlighted that the MME was not able to correctly represent the response of yield to increasing sowing rate at early sowing dates and the response to sowing date at the currently recommended sowing rate. Some of the models showed better performance than the MME in predicting grain yield at an early sowing date, but none was more accurate than the MME at a low sowing rate .Although previous studies have shown that MMEs were effective in reducing uncertainty in predicting yield .Fig. S2. Measured normalized difference vegetation index, measured and simulated fraction of intercepted PAR, and total above ground biomass and grain yield versus days after sowing for wheat crops sown on 20 February, 10 March, 26 March, and 23 April 2014 at the locally recommended density (150 seeds mTable S1. List of the 29 wheat crop models used in the AgMIP Wheat Phase 4 studyTable S2. Statistical evaluation of model error and interannual variability of measured and simulated grain yield, considering wheat sown at the locally recommended sowing date and plant density.Table S3. Statistical evaluation of model error in grain yield, considering wheat sown at the locally recommended plant density vs low sowing density.Table S4. Statistical evaluation of model error in grain yield, considering wheat sown at the locally recommended date versus early sowing.Protocol S1. Crop model performance and evaluation metrics.erac221_suppl_Supplementary_MaterialsClick here for additional data file."}
{"text": "Chem. Chem. Phys., 2022, 24, 9403\u20139410, https://doi.org/10.1039/D2CP00686C.Correction for \u2018Modeling the heating and cooling of a chromophore after photoexcitation\u2019 by Elizete Ventura  The published version of this article contained errors in part of the funding information in the Acknowledgements. The corrected funding information for M. T. do C., J. M. T. and M. B. is as follows: M. T. do C., J. M. T. and M. B. have received funding from the European Union\u2019s Horizon 2020 research and innovation programme under the grant agreement no. 828753.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "After having been in contact with the authors, they agreed with the decision to retract the paper. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors' attention by a concerned reader that certain of the colony formation assay data shown in Fig. 2C and the tumor images shown in Fig. 2E were similar to data appearing in different form in other articles by different authors. Owing to the fact that the contentious data in the above article had already been published elsewhere, or were already under consideration for publication, prior to its submission to"}
{"text": "In the original publication , there wFigure 8 legend becomes:t-test p-value equal to 0.005.Clustering analysis from Inception V3 deep learning features based on combined superficial and deep OCT-As. The mean 1-year BVCA for C1 and C2 was 66.67 and 49.1, respectively, with a In the original publication, there was a mistake in There was an error in the original publication. Values for C1 and C2 were inverted.p = 0.005)A correction has been made to Abstract, sentence: best-corrected visual acuity (BCVA) C1 = 49.10 (18.60 SD) and BCVA C2 = 66.67 . best-corrected visual acuity (BCVA) C1 = 66.67 (16.00 SD) and BCVA C2 = 49.10 A correction has been made to Results, Paragraph 9, sentence: In this configuration, the mean of letters for C1 and C2 was 49.1 and 66.67, respectively, with a The sentence becomes:t-test p-value equal to 0.005 .In this configuration, the mean of letters for C1 and C2 was 66.67 and 49.1, respectively, with a The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "Computational and Mathematical Methods in Medicine has retracted the article titled \u201cLiraglutide Is Protective against Brain Injury in Mice with Febrile Seizures by Inhibiting Inflammatory Factors\u201d [Factors\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifi"}
{"text": "Acta Cryst. (2014), E70, o72.Corrigendum to  et al. , there is an error in the order of the authors.In the paper by Chang"}
{"text": "In the Rare disease awareness and patient advocacy subsection of the Results, there is an error in the second sentence of the third paragraph. The correct sentence is: Additionally, there are also many other societies, such as the Welfare Association for Dwarfism Malaysia and Spinal Muscular Atrophy (SMA) Malaysia, that represent patients according to the specific disorder."}
{"text": "Therefore, two partial overlapping cropped images of the same field (striatum anti-GFAP WT\u00a0+ CLR01) were used in the panel.The correct version of Figure\u00a04A is included here. The authors apologize for the error."}
{"text": "The authors would like to make the following corrections to the published paper . ReplaciThe authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "In \u201cA Web-Based Prostate Cancer\u2013Specific Holistic Needs Assessment (CHAT-P): Multimethod Study From Concept to Clinical Practice\u201d : e32153]) the authors noted one error in the order of the authors.The author list appeared as:Rebecca Appleton, Veronica Nanton, Nisar Ahmed, Joelle Loew, Julia Roscoe, Radha Muthuswamy, Prashant Patel, Jeremy Dale, Sam H AhmedzaiWhereas it should have been:Veronica Nanton, Rebecca Appleton, Nisar Ahmed, Joelle Loew, Julia Roscoe, Radha Muthuswamy, Prashant Patel, Jeremy Dale, Sam H Ahmedzaist November 2022, together with the publication of this correction notice. Because this was made after submission to PubMed, PubMed Central, and other full-text repositories, the corrected article has also been resubmitted to those repositories.The correction will appear in the online version of the paper on the JMIR Publications website on 1"}
{"text": "In the published paper the Acknowledgements section was omitted; this should read:This work was supported by Major Scientific and Technological Projects of Guangzhou Science and Technology Plan Projects (No. 201802020004).The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "RSC Advances article due to concerns with the reliability of the data in the published article.The Royal Society of Chemistry, with the agreement of the named authors, hereby wholly retracts this Repeating fragments can be observed in the XRD spectrum for GONs in Fig. 1C, which indicates that it has been manipulated. In addition, there are unexpected similarities in the baseline of the XRD data presented for MWCNTs and AC  in the 32.5\u201340\u00b0 and 45\u201357.5\u00b0 regions.Given the significance of the concern about the validity of the data, the findings presented in this paper are no longer reliable.Signed: Yubing Sun, Dadong Shao, Guixia Zhao, Shubin Yang and Xiangke Wangth March 2020Date: 27Changlun Chen, Jiaxing Li and Xiaoli Tan were contacted but did not respond.RSC AdvancesRetraction endorsed by Laura Fisher, Executive Editor,"}
{"text": "Due to a production error, affiliations 9 and 10 are incorrect.9LEPSE, Univ Montpellier, INRAE, Institut Agro, Montpellier, France\u201d it should be \u201c9CEFE, Univ Montpellier, CNRS, EPHE, Institut Agro, IRD, Montpellier, France.\u201dFor affiliation 9, instead of \u201c10CEFE, Univ Montpellier, CNRS, EPHE, Institut Agro, IRD, Universit\u00e9 Paul Valery Montpellier, Montpellier, France\u201d it should be \u201c10LEPSE, Univ Montpellier, INRAE, Institut Agro, Montpellier, France.\u201dFor affiliation 10, instead of \u201c1,9,\u201d \u201cElena Kazakou10,\u201d and \u201cDenis Vile9,\u201d it should be \u201cJustine Floret1,10,\u201d \u201cElena Kazakou9,\u201d and \u201cDenis Vile10.\u201dIn addition, there was an error regarding the affiliations for Justine Floret, Elena Kazakou, and Denis Vile. Instead of \u201cJustine FloretThe publisher apologizes for this mistake. The original article has been updated."}
{"text": "Dear Editor,We read the letter of Chen et\u00a0al. with interest and we thank the authors for pointing out an inadvertent error in our manuscript . We noti"}
{"text": "A 52\u2010year\u2010old man, who 8 months previously received single\u2010unit cord blood transplantation for acute myeloid leukemia, presented with a 4\u2010day history of nonproductive cough and sore throat. Chest radiography and computed tomography revealed the presence of bilateral ground glass opacities affecting mainly the upper lobes Figure\u00a0. TestingThe authors declare no conflict of interest.All authors participated in the care of the patient. Takaaki Konuma wrote the first manuscript draft."}
{"text": "Adv. Sci. 2021, 9, 210488410.1002/advs.202104884DOI: In the subpart \u201c2.5. Enzymatic\u2010Photocatalytic Heterogeneous Cascade Reactions of Enzyme\u2010Photocatalyst in Suprastructures\u201d of the original published article, the citation of the Equation are wrongly displayed. The corrected part is shown below:Then, the produced proton helps the oxidization of iodide into iodine in the presence of hydrogen peroxide, as described in[52]Equation\u00a0.[52]..4).[55,5The authors apologize for any inconvenience caused."}
{"text": "DOI: 10.1039/D0RA10177JCorrection for \u2018The highly efficient removal of HCN over Cu The authors regret that in the original manuscript, the author affiliations corresponding to the letters a and b were the wrong way round, meaning the authors were associated with the wrong affiliations.The correct affiliation information is as given in this correction notice.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "K. Jesudoss  RSC Advances article due to concerns with the reliability of the data.The Royal Society of Chemistry, with the agreement of the authors, hereby wholly retracts this In Fig. 2 the data for (a), (b) and (c) contains sections of identical noise.In Fig. 7 there are several instances of overlapping images. Fig. 7a and e are identical, Fig. 7b and f have partial overlap, and Fig. 7c and d have partial overlap.Given the significance of these concerns, the findings presented in this paper are no longer reliable.Signed: S. K. Jesudoss, J. Judith Vijaya, K. Kaviyarasu, L. John Kennedy, R. Jothi Ramalingam, Hamad A. Al-Lohedanth August 2022.Date: 18RSC Advances.Retraction endorsed by Laura Fisher, Executive Editor,"}
{"text": "Declaration of Competing Interest statements were not included in the published version of the following article that appeared in the August 2021 issue of Comprehensive Psychoneuroendocrinology.The appropriate Declaration/Competing Interest statements, provided by the Authors, are included below.\u201cLove, fear, and the human-animal bond: On adversity and multispecies relationships\u201d  10.1016/j.cpnec.2021.100071. Declaration of competing interest: The Authors have no interests to declare."}
{"text": "Scientific Reports 10.1038/srep39950, published online 2 February 2017Retraction of: 1 to address these issues. However, additional concerns have been raised:p-IkB\u03b1 lanes 2 and 3 in Fig.\u00a01f. appear highly similar to p65 lanes 1 and 2 in Fig.\u00a03d;IkB\u03b1 lanes 4 and 5 in Fig.\u00a01f. appear highly similar;IKK\u03b1 lanes 1 and 2 in Fig.\u00a01g appear to be highly similar to lanes 3 and 4;Fig.\u00a06a appears to contain duplicated data patterns in the flow cytometry plots representing the 10 and 20\u00a0\u03bcM groups .Given these additional concerns, the Editors no longer have confidence in the presented data.The Editors have retracted this Article. After publication, concerns were raised regarding partial image duplication in Figs. 1g, 2e, 5a,b, 6b and 8e. The Authors issued a CorrectionQinglong Guo does not agree to this retraction. Xuefen Xu, Xiaobo Zhang, Yi Zhang, Lin Yang, Yicheng Liu, Shaoliang Huang, Lu Lu, Lingyi Kong, Zhiyu Li, and Li Zhao have not responded to any correspondence from the Editors or publisher about this retraction."}
{"text": "The Science of Nature grants the Arnold Berliner Award to an article\u2019s lead author who is distinguished by excellent, original, and\u2014especially\u2014interdisciplinary research. As such, the winning articles clearly reflect the vision of Arnold Berliner (Autrum Every year, r Autrum . Springer Autrum , a 2-yeaI am very proud that, this year, the Editorial Board has decided to award Samuel Zschokke Fig.\u00a0 for his On behalf of the Editorial Board, I congratulate Samuek Zschokke and his team on the award."}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors\u2019 attention by a concerned reader that the Bcl-2 protein western blotting data shown in Fig. 2D were strikingly similar to data appearing in different form in another article written by different authors who were based at different research institutes. Owing to the fact that the contentious data in the above article were already under consideration for publication prior to its submission to"}
{"text": "Computational and Mathematical Methods in Medicine has retracted the article titled \u201cDesign of Exercise Nursing Program for Pelvic Floor Muscle Function Recovery at 42 Days Postpartum\u201d [tpartum\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifiThe authors do not agree to the retraction."}
{"text": "RSC Advances article due to a lack of reproducibility in the results of the paper. We have been unable to replicate the results of miRNA detection, shown in Fig. 8, and as a result, the conclusions of this paper are not supported.We, the named authors, hereby wholly retract this Signed: Erlin Sun, Lining Wang, Xiaodong Zhou, Chengquan Ma, Yan Sun, Mingde Lei, Bingxin Lu and Ruifa Hanth July 2020Date: 14RSC AdvancesRetraction endorsed by Laura Fisher, Executive Editor,"}
{"text": "Journal of Healthcare Engineering has retracted the article titled \u201cEffect of EPOC on Serum MicroRNA Expression in Patients with Hypertension\u201d [tension\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifiThe author does not agree to the retraction."}
{"text": "The authors wish to make the following corrections to this paper :In the original publication, there was a mistake in"}
{"text": "They also regret any inconvenience caused to the readership of the Journal.After having examined their original data, the authors have realized that inadvertent errors were made during the process of compiling these figures. Corrected versions of"}
{"text": "Pseudomonas aeruginosa via LasIR/RhlIR circuitry\u2019 by Mayank D. Shah et al., RSC Adv., 2019, 9, 40228\u201340239.Correction for \u2018Potassium 2-methoxy-4-vinylphenolate: a novel hit exhibiting quorum-sensing inhibition in  The authors would like to add affiliation d as the current affiliation for Prashant S. Kharkar. The corrected list of affiliations is as shown above.The authors regret that one of the affiliations (affiliation The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "The authors wish to make the following corrections to this paper :For The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. The original publication has also been updated."}
{"text": "Scientific Reports 10.1038/s41598-019-50538-w, published online 01 November 2019Retraction of: The Authors have retracted this Article.Subsequent to the publication of a Correction , a numbeShady Kotb, Robert Pola, Michal Pechar, Rajiv Kumar, Bijay Singh, Reza Taleeli, Florian Trichard, Vincent Motto-Ros, Lucie Sancey, Alexandre Detappe, Sayeda Yasmin-Karim, Andrea Protti, Ilanchezhian Shanmugam, Thomas Ireland, Tomas Etrych, Srinivas Sridhar, Olivier Tillement, Mike Makrigiorgos, and Ross I. Berbeco agree with the retraction and its wording. Sijumon Kunjachan and Felix Gremse did not respond to the correspondence about this retraction."}
{"text": "Countrywide multi-serotype outbreak of Salmonella Bovismorbificans ST142 and monophasic Salmonella Typhimurium ST34 associated with dried pork sausages in France, September 2020 to January 2021\u2019 by Pardos de la Gandara et al., upon publication on 12 January 2023, the title was missing the year of 2020 after September. This was corrected on 13 January 2023 at the request of the authors.In the article \u2018"}
{"text": "This abstract has been withdrawn"}
{"text": "Correction : Stem Cell Research & Therapy (2022) 12:344 10.1186/s13287-021-02423-5Following the publication of this article, the authors regretfully found two errors in the article and would like to make corrections:18F-FDG uptake between different treatments for Fig.\u00a0In Figure 1b, the 1st image of hBMSCs was chosen incorrectly. In Figure 5a, the 2nd image in the first row  was chosen incorrectly. This mistake occurred due to the carelessness in picking the representative images when the authors tried to compare the morphology for hBMSCs and hEMSCs (Fig.\u00a0The corrected 1st image in Fig.\u00a0Please note that these corrections do not affect the results and conclusions of our publication and all the authors have agreed on the correction of this negligence. We apologize to the Editor and the readership of the journal for any inconvenience it caused."}
{"text": "Page 5, Volume 9, no. 2, e01185-21, 2021, Correction of this figure does not change the conclusions of this paper."}
{"text": "Journal of Healthcare Engineering has retracted the article titled \u201cBiometric Recognition of Finger Knuckle Print Based on the Fusion of Global Features and Local Features\u201d [eatures\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifi"}
{"text": "This abstract has been withdrawn"}
{"text": "Computational and Mathematical Methods in Medicine has retracted the article titled \u201cAnalysis of the Mechanism and Safety of Bisphosphonates in Patients with Lung Cancer and Bone Metastases\u201d [astases\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifiThe authors agree to the retraction."}
{"text": "The authors would like to make corrections to a recently published paper .https://www.marinepharmacology.org/ (accessed on 30 September 2022) [The authors wish to acknowledge the web resource at Names of Marine Natural ProductsWrong or Incomplete NCT CodesCorrected NCT CodesPhase IIIPlitidepsin (depsipeptide)[NCT0478455][NCT04784559]Marizomib[NCT03345095][NCT03345095][NCT00667082]Phase IIRC88 (MMAE)[NCT0417584][NCT04175847]ARX788 (auristatin variant)[NCT03319628][NCT04829604]In Table 3, the NCT codes listed below have been corrected.The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. The original publication has also been updated."}
{"text": "Georgia Mavria was not included as an author in the original publication, the correct authorship is as below:The authors wish to make the following corrections to this paper :1.\u00a0Addi1,*, Gary C. Shaw 1, Daniel Tams 1, Tim Brend 1, Hitesh Sanganee 2, Simon T. Barry 3, Gregory Hamm 4, Richard J. A. Goodwin 4, John G. Swales 4, Henry King 1, Lynette Steele 1, Ruth Morton 1, Anastasia Widyadari 1, Thomas A. Ward 1, Filomena Esteves 1, Marjorie Boissinot 1, Georgia Mavria 1, Alastair Droop 5, Sean E. Lawler 6 and Susan C. Short 1,*The author contribution should also be updated to include GM as below:Anke Br\u00fcning-Richardson 2.\u00a0Email CorrectionConceptualization, S.C.S. and A.B.-R.; methodology, A.B.-R., G.C.S., D.T., T.B., H.S., S.T.B., G.H., R.J.A.G., J.G.S., H.K., L.S., R.M., A.W., T.A.W., F.E., M.B., A.D., G.M.; software, A.D.; validation, S.C.S., S.E.L.; formal analysis, S.C.S., G.C.S., A.B.-R.; investigation, A.B.-R., G.C.S., D.T., T.B., H.S., S.T.B., G.H., R.J.A.G., J.G.S., H.K., L.S., R.M., A.W., T.A.W., F.E., M.B., A.D.; resources, H.S., S.T.B., G.H., R.J.A.G.; data curation, S.C.S., A.D.; writing\u2014original draft preparation, A.B.-R., S.C.S., S.E.L.; writing\u2014review and editing, S.C.S., S.E.L.; visualization, A.B.-R., S.C.S.; supervision, S.C.S.; project administration, S.C.S.; funding acquisition, S.C.S., A.B.-R. All authors have read and agreed to the published version of the manuscript.3.\u00a0Text CorrectionThe correct email address of Susan C. Short is s.c.short@leeds.ac.ukWe have also been alerted to an error in affiliation in the text of the paper: In Section 2.1 Cell lines, sentence 2 and 3: In addition, patient-derived cell lines GBM1 and GBM4 [15] were included in this study. Neural progenitor cells (NP1) and normal human astrocytes (NHA) were obtained from Dr Heiko Wurdak (Leeds Institute of Cancer and Pathology). It should be replaced with the following: The patient-derived tumour models GBM1, GBM4, and the adult human brain progenitor line NP1 were a kind gift from H. Wurdak  and were used as previously described in .The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. The original article has been updated."}
{"text": "In \u201cMultimedia Knowledge Translation Tools for Parents About Childhood Heart Failure: Environmental Scan\u201d :e34166) the authors noted one error.In the originally published paper, Multimedia Appendix 1 contained one incorrect value. In the \u201cDuplicate apps removed before screening\u201d box, the value was listed as \u201c6\u201d.In the corrected version of the paper, In the \u201cDuplicate apps removed before screening\u201d box, the value is listed as \u201c5\u201d. The updated version of Multimedia Appendix 1 is available below.The correction will appear in the online version of the paper on the JMIR Publications website on June 21, 2022, together with the publication of this correction notice. Because this was made after submission to PubMed, PubMed Central, and other full-text repositories, the corrected article has also been resubmitted to those repositories."}
{"text": "The publisher regrets that the Informed Consent statement for this paper was not published in the final version. The relevant Informed Consent statement can be found below:Informed consent\u201cThis article including the images was published with permission of both patients.\u201dThe publisher would like to apologise for any inconvenience caused."}
{"text": "The authors wish to make the following correction to the published paper :Figure 6 data that do not belong to the analyzed samples. Therefore, Figure 6 and the corresponding discussion must not be considered part of the work.The original paper erroneously reports in ** Materials and Methods **, ** Au@LCC Synthesis and Characterization **, ** 2.1 **:A correction has been made to ** XPS spectra were acquired using a Thermo Scientific system, equipped with a monochromatic Al-Ka source (1486.6 eV), operating in a constant analyzer energy (CAE) mode with a pass energy of 20 eV for high-resolution spectra and a spot size of 400 \u03bcm. X-ray diffraction (XRD) patterns were recorded in the 2 theta range from 20\u00b0 to 80\u00b0 using a Bruker D8 Advance X-ray diffractometer with Cu Ka radiation (1.5406 \u00c5). **The last sentences now read: ** Results **, ** Physico-Chemical Characterization of Au@LCC Nanocolloids **, ** 3.1 **:A correction has been made to The original Figure 6 and the corresponding explanatory text have been removed and the subsequent figures have been renumbered accordingly.The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. The original publication has been updated."}
{"text": "Journal of Healthcare Engineering has retracted the article titled \u201cRelationship between Artificial Intelligence-Based General Anesthetics and Postoperative Cognitive Dysfunction\u201d [unction\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifi"}
{"text": "The authors regret that incorrect details were given for ref. 22, 26 and 81 in the original article. The correct versions of ref. 22, 26 and 81 are given below.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "College of Life Sciences, Henan Normal University, Xinxiang, Henan, China.The Observation and Research Field Station of Taihang Mountain Forest Ecosystems of Henan Province, Xinxiang, Henan, China.In the recent article by Chen et al. , the thiWe apologize for the inconvenience this may cause."}
{"text": "Due to a production error, the \u201c\u2020\u201d symbol, denoting \u201cThese authors have contributed equally to this work,\u201d was attached to authors Hao Li and Li-Wen Gu. It should be attached to authors Hao Li and Xiao-Gang Liu.The publisher apologizes for this mistake. The original version of this article has been updated."}
{"text": "Furthermore, they apologise to the readership for any inconvenience caused.The authors have re-examined their data and realized that"}
{"text": "Retraction Note to: Nanoscale Res Lett (2021) 16:63 10.1186/s11671-021-03520-3The Editors in Chief have retracted this article. After publication, concerns were raised concerning the appearance of Western blots and a possible similarity between the STAT3 bands in Fig.\u00a05 b and e. The authors did not respond to requests for further clarification and did not supply raw images or the ethics permit. The editors, therefore, have lost confidence in the integrity of the article's findings. The editor was not able to obtain a current email address for Authors Shuai Zhang and Jingyan Liang. Authors have not responded to any correspondence from the editor or publisher about this retraction."}
{"text": "Figs. 4i and 5f appear to contain overlap;Figs. 4e and 6i appear to contain overlap;Figs. 4h and 6a appear to share the same control bands (stretched/squished);There are similarities in various groups in Fig.\u00a06e;Figs. S4a and S4c appear to contain the same gel with different exposure (as a mirror image).The Editors-in-Chief have retracted this article. After publication, concerns were raised regarding the data presented in Figs.\u00a04\u20136 and S4. Specifically:The authors have been unable to provide the full raw data to address these concerns.\u00a0The Editors-in-Chief therefore no longer have confidence in the presented data.Ruby Singh does not agree to this retraction. Yousuf Ansari and Pradeep Das have not explicitly stated whether they agree to this retraction notice. Bidyut Purkait, Kumar Abhishek, Savita Saini, Sushmita Das, Sudha Verma, Abhishek Mandal, Ayan Kr. Ghosh, Ashish Kumar, Abul H. Sardar, Ajay Kumar and Pradeep Parrack have not responded to any correspondence from the editor or publisher about this retraction."}
{"text": "This abstract has been withdrawn"}
{"text": "National Science Centre, Poland, grant no. DEC-2012/06/M/NZ4/00138 granted to Wojciech Fortuna was not included. The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated.In the original publication , the fun"}
{"text": "Said  RSC Advances article because the enzymes GPP and FPP synthase used in the paper were genetically engineered by another colleague and used without permission. In addition, the synthesis of phospholipids as described in the paper was done according to unpublished PhD thesis work and we did not have permission to publish it.We, the named authors, hereby wholly retract this Signed: Madhukar S. Said, Govinda R. Navale, Jayant M. Gajbhiye and Sandip S. Shindeth January 2020Date: 8RSC AdvancesRetraction endorsed by Laura Fisher, Managing Editor,"}
{"text": "Correction to: Current Treatment Options in Oncology (2022) 23:1503-152110.1007/s11864-022-01006-7The original version of this article, unfortunately, contained mistakes.The author list was arranged incorrectly. The correct sequence of authors is presented below:Jingqin Zhong, MDWangjun Yan, PhDChunmeng Wang, PhDWanlin Liu, MDXinyi Lin, MDZijian Zou, MDWei Sun, PhD*Yong Chen, PhD**Email: Yong Chen, chenyong@fudan.edu.cn; Wei Sun, wsun14@fudan.edu.cn"}
{"text": "Retraction Note: BMC Anesthesiol 22, 20 (2022)https://doi.org/10.1186/s12871-021-01542-zThe authors have retracted this article because they did not obtain ethics committee approval for changes to the protocol of their study.All authors agree to this retraction."}
{"text": "Retraction Note:J Exp Clin Cancer Res39, 186 (2020)https://doi.org/10.1186/s13046-020-01697-6Fig. 4C appears to contain image overlap between different treatment groups and cell lines.Fig. 4F appears to contain overlapping areas with two articles on unrelated circRNAs that were under consideration within a similar time frame , 2.Figs. 6G and 7G appear to contain image overlap between different treatment groups and cell lines.The Editor-in-Chief has retracted this article at the authors' request. After publication, concerns were raised regarding the published images. Specifically:The authors have stated that the microscopy images in Fig. 4F were provided by a third party.Due to the number of concerns with the images, the Editor-in-Chief and the authors no longer have confidence in the presented data.All authors agree to this retraction."}
{"text": "On page 36478 for According to this error, \u03b1 value of BaTiO3@Ni\u2013P/PVDF has increased distinctly within the frequency ranges of 2\u201311.3, 12.7\u201315.3, and 16.6\u201318 GHz compared with that of BaTiO3/PVDF. In addition, the BaTiO3@Ni\u2013P/PVDF/PANI sample clearly exhibits a higher attention constant \u03b1 than that of BaTiO3@Ni\u2013P/PVDF within the frequency range of 8.8\u201318 GHz\u201d to \u201cthe attention constant \u03b1 is in the order: BaTiO3@Ni\u2013P/PVDF > BaTiO3@Ni\u2013P/PVDF/PANI > BaTiO3/PVDF > PVDF\u201d.In addition, the corresponding description in the text (pp. 36478\u201336479) should be corrected from \u201cthe attenuation constant The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "We regret that the original version of our paper unfortunately contained some incorrect representative images. The images of migrated and invaded MHCC97H cells with miR-302c-3p mimics transfection in Figure"}
{"text": "Computational Intelligence and Neuroscience has retracted the article titled \u201cA Quantitative Analysis of Country Relations in Foreign Direct Investment\u201d [estment\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifiThe authors agree to the retraction."}
{"text": "The authors thank you for reading this erratum and apologize for any inconvenience caused."}
{"text": "In the recent article by Olivera\u2010Hyde et al.\u00a0, the autJess Jones: Conceptualization ; funding acquisition ; investigation ; project administration ; resources ; supervision ; writing \u2013 review & editing .We apologize for these errors."}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of the above paper, it was drawn to the Editors' attention by a concerned reader that certain of the flow cytometric data featured in Figs. 2D, 4D and 5D, the colony formation assay data shown in Figs. 2C, 4C and 5C, and the tumor images shown in Fig. 7A were strikingly similar to data appearing in different form in other articles by different authors. Owing to the fact that the contentious data in the above article were already under consideration for publication, or had already been published, prior to its submission to"}
{"text": "Bioscience Reports at the request of the Editor-in-Chief and the Editorial Board following receipt of a notification from a reader, alerting the Editorial Board to what appear to be duplicate regions between two panels of Figure 7B; specifically, between the miR-140-5p inhibitor panel and the miR-140-5p inhibitor+si-Notch1 panel. The Editorial Office has also identified similar regions in two panels of Figure S3, between the miR-140-5p inhibitor panel and the si-NC panel. There are additional concerns regarding the western blots from figures 2, 3, 5, 9, S1 and S5. The authors have been contacted with regards to the retraction and have not responded to the Journal's queries or the concerns raised. Given the extent of the issues raised, the Editorial Board stand by the decision to retract the article.This Retraction follows an Expression of Concern relating to this article previously published by Portland Press. This article is being retracted from"}
{"text": "The journal retracts the article, \u201cAEG-1/miR-221 Axis Cooperatively Regulates the Progression of Hepatocellular Carcinoma by Targeting PTEN/PI3K/AKT Signaling Pathway\u201d [We have been made aware that a number of figures in the paper cited above  contain We apologize to our readership that this went undetected until now."}
{"text": "Adaptive single-KIR+NKG2C+ NK cells expanded from select superdonors show potent missing-self reactivity and efficiently control HLA-mismatched acute myeloid leukemia. J Immunother Cancer 2022;10:e005577. doi: 10.1136/jitc-2022-005577Haroun-Izquierdo A, Vincenti M, Netskar H, This article has been updated since it was first published online. The paragraph under the heading \u2018ADAPT-NK cell expansion protocol\u2019 has been updated to include the sentence \u201810% human ab serum , 2mM L-glutamine (Cytiva-FisherScientific)\u2019."}
{"text": "Zr\u2010bptc  shows a high SO2 uptake of 6.2\u2005mmol\u2009g\u22121 at 0.1\u2005bar and 298\u2005K, reflecting excellent capture capability and removal of SO2 at low concentration (2500\u2005ppm). Dynamic breakthrough experiments confirm that the introduction of amine, atomically\u2010dispersed CuII or heteroatomic sulphur sites into the pores enhance the capture of SO2 at low concentrations. The captured SO2 can be converted quantitatively to a pharmaceutical intermediate, aryl N\u2010aminosulfonamide, thus converting waste to chemical values. In situ X\u2010ray diffraction, infrared micro\u2010spectroscopy and inelastic neutron scattering enable the visualisation of the binding domains of adsorbed SO2 molecules and host\u2013guest binding dynamics in these materials at the atomic level. Refinement of the pore environment plays a critical role in designing efficient sorbent materials.We report reversible high capacity adsorption of SO 2 uptake. The incorporation of atomically\u2010dispersed CuII, amine or heteroatomic sulphur sites enhances the uptake of SO2 at low concentrations. This work confirms that control of pore environments is an important approach for optimising the adsorption of SO2 at low concentrations.A series of Zr\u2010based metal\u2013organic framework materials have been investigated for reversible SO MOFs constructed from {Zr6} clusters are renowned for their high stability. and Zr\u2010DMTDC6(\u03bc3\u2010O)4(\u03bc3\u2010OH)4(OOCR)12} clusters bridged by dicarboxylates to give cubic structures of fcu topology 4(\u03bc3\u2010OH)4(OOCR)12} clusters and tetracarboxylate ligands in an open framework of ftw topology.2\u2009g\u22121. MFM\u20101336(OH)8(OH)8(OOCR)8} clusters and thcb4\u2212 ligands \u20102,2\u2032,4,4\u2032,6,6\u2032\u2010hexamethyl\u20101,1\u2032\u2010biphenyl) to form a flu topology. MFM\u2010133 shows an axially elongated octahedral cage (10.4\u00d710.4\u00d725.9\u2005\u00c5) and a BET surface area of 2156\u2005m2\u2009g\u22121 8(OH)8(OOCR)8} clusters with the tetratopic ligand 3,3\u2032\u2032,5,5\u2032\u2032\u2010tetrakis(4\u2010carboxyphenyl)\u2010p\u2010terphenyl (H4tcpt) to give a neutral framework of sqc topology. MFM\u2010422 is comprised of a trigonal cage  and a hexagonal cage .Zr\u2010bptc is built from 12\u2010connected {Zr2 have been recorded for these MOFs at 273\u2013298\u2005K and from 0\u20131\u2005bar  (36.7\u2005mmol\u2009g\u22121) under the same conditions.2, UiO\u201066\u2010CuII, Zr\u2010DMTDC, Zr\u2010bptc, MFM\u2010133 and MFM\u2010422, show fully reversible uptakes of SO2 of 8.6, 8.8, 8.2, 9.6, 7.8, 8.9 and 13.6\u2005mmol\u2009g\u22121, respectively . The comparable adsorption uptakes of UiO\u201066, UiO\u201066\u2010NH2 and UiO\u201066\u2010CuII at 1\u2005bar (8.2\u20138.8\u2005mmol\u2009g\u22121) suggest that decoration of the pore environment with functional groups or open CuII sites has little impact on the total uptake capacity, which is determined primarily by the surface area. The slightly higher uptake of Zr\u2010DMTDC (9.6\u2005mmol\u2009g\u22121) is consistent with its higher surface area (1345\u2005m2\u2009g\u22121), compared with the other three UiO\u201066 materials. In contrast, enhancements in the uptake at 0.1\u2005bar were observed for UiO\u201066\u2010NH2, UiO\u201066\u2010CuII and Zr\u2010DMTDC, compared with UiO\u201066  for SO2 uptake show decreasing values of 45\u201350, 44\u201332, 38\u201334, 32\u201329, 37\u201327, 31\u201327 and 26\u201319\u2005kJ\u2009mol\u22121 for Zr\u2010bptc, UiO\u201066\u2010NH2, UiO\u201066\u2010CuII, Zr\u2010DMTDC, UiO\u201066, MFM\u2010422 and MFM\u2010133, respectively. Compared with UiO\u201066, the materials UiO\u201066\u2010NH2, UiO\u201066\u2010CuII and Zr\u2010DMTDC show higher values for Qst, consistent with the enhanced adsorption at low pressure. The relatively low values of Qst for MFM\u2010133 and MFM\u2010422 are consistent with their large pores, reducing the strength of host\u2013guest interactions.Gravimetric adsorption isotherms of SO2 and N2 have also been recorded for Zr\u2010bptc, UiO\u201066\u2010NH2, UiO\u201066\u2010CuII, Zr\u2010DMTDC and UiO\u201066 to assess the adsorption selectivity 2/CO2 (1/99) and SO2/N2 (1/99)  at 298\u2005K and 1.0\u2005bar. UiO\u201066, UiO\u201066\u2010NH2, Zr\u2010DMTDC and UiO\u201066\u2010CuII exhibit retention times for SO2 in the expected order of 33, 53, 58 and 100\u2005min\u2009g\u22121, respectively  with retention times of 80, 175, 157 and 175\u2005min\u2009g\u22121 for UiO\u201066, UiO\u201066\u2010NH2, Zr\u2010DMTDC and UiO\u201066\u2010CuII, respectively  and SO2/N2 (2500\u2005ppm SO2/75\u2009% CO2 in He), respectively 4(bdc)6\u2009\u22c5\u2009(SO2)7.7] reveal two binding sites I and II located in cage T (SO2/{Zr6}=5.1) and cage O (SO2/{Zr6}=2.6), respectively \u2005\u00c5] and dipole\u2013dipole interaction [O2S\u22c5\u22c5\u22c5phenyl ring=3.69(2)\u2005\u00c5] stabilise SO2 (I)  is stabilised by two hydrogen bonds  4(bdc\u2212NH2)6\u2009\u22c5\u2009(SO2)8.1], two binding sites I\u2032 and II\u2032 are observed in cage T (SO2/{Zr6}=4.7) and cage O (SO2/{Zr6}=3.4), respectively \u2005\u00c5] was identified and works together with an interaction [O2S\u22c5\u22c5\u22c5phenyl ring=3.58(1)\u2005\u00c5] and hydrogen bonding [OSO\u22c5\u22c5\u22c5\u03bc3\u2010HO=2.94(5)\u2005\u00c5] that stabilise SO2 binding at site I\u2032 \u2005\u00c5, SO2\u22c5\u22c5\u22c5NH2=1.73(3), 2.43(6), 2.87(7), 3.21(1), 3.30(3) and 3.63(8)\u2005\u00c5], which work together with two further dipole\u2013dipole interactions [O2S\u22c5\u22c5\u22c5NH2=2.40(4) and 3.10(7)\u2005\u00c5] to stabilise SO2 at site II\u2032 4(DMTDC)2\u2009\u22c5\u2009(SO2)13.1], four binding sites were revealed (I\u2032\u2032\u2010IV\u2032\u2032). Sites I\u2032\u2032, II\u2032\u2032 and III\u2032\u2032 are localised in cage T   and 3.52(7)\u2005\u00c5; O2S\u22c5\u22c5\u22c5thiophene ring=3.65(3)\u2005\u00c5]  and 2.70(4)\u2005\u00c5; O2S\u22c5\u22c5\u22c5thiophene ring=3.72(3) and 3.72(3)\u2005\u00c5] and supramolecular interaction [O2S\u22c5\u22c5\u22c5\u03bc3\u2010O=3.63(9)\u2005\u00c5]. In addition, dipole\u2013dipole interaction between SO2 at sites I\u2032\u2032 and II\u2032\u2032 [OSO(I\u2032\u2032)\u22c5\u22c5\u22c5SO2(II\u2032\u2032)=2.81(7)\u2005\u00c5] was identified \u2005\u00c5] and [OSO\u22c5\u22c5\u22c5S\u2010ring=3.97(6)\u2005\u00c5] were identified between SO2(III\u2032\u2032) and the framework  and 3.77(8)\u2005\u00c5] and a hydrogen bond [OSO\u22c5\u22c5\u22c5H3C=2.42(2)\u2005\u00c5] 4(bptc)3\u2009\u22c5\u2009(SO2)5.8], six binding sites were revealed (I\u2013VI) \u2005\u00c5] and by two hydrogen bonds [OSO\u22c5\u22c5\u22c5H\u2212C=2.79(8)\u2005\u00c5 and OSO\u22c5\u22c5\u22c5\u03bc3\u2010OH=2.36(5)\u2005\u00c5] \u22c5\u22c5\u22c5SO2(I)=2.06(8) and 3.07(2)\u2005\u00c5, OSO(I)\u22c5\u22c5\u22c5SO2(II)=3.28(1)\u2005\u00c5] with SO2 at site I \u22c5\u22c5\u22c5OSO(V)=2.99(7)\u2005\u00c5, OSO(III)\u22c5\u22c5\u22c5SO2(V)=3.13(5)\u2005\u00c5] with SO2 at site V immobilised by dipole\u2013dipole interactions [O2S\u22c5\u22c5\u22c5phenyl ring=3.72(5)\u2005\u00c5] and two\u2010fold electrostatic interactions [OSO\u22c5\u22c5\u22c5H\u2212C=2.78(1) and 2.93(9)\u2005\u00c5] \u2005\u00c5] and dipole\u2013dipole interaction [OSO(IV)\u22c5\u22c5\u22c5SO2(VI)=3.83(5)\u2005\u00c5] with SO2 at site VI , 1.88(6), 2.23(5), 2.23(5) and 2.69(7)\u2005\u00c5] and two dipole\u2013dipole interactions [O2S\u22c5\u22c5\u22c5OOC=3.07(2) and 3.07(2)\u2005\u00c5]  and carboxylic groups and multiple strong hydrogen bonding at site VI jointly facilitate the exceptional SO2 uptake at low pressure.In SO2 (0\u20131\u2005bar) in the UiO\u201066 type systems have been analysed by in situ synchrotron infrared micro\u2010spectroscopy. For all the MOFs, clear binding of SO2 to the hydroxyl group is observed with a red shift of the \u2212OH stretching vibration at \u22483671\u2005cm\u22121 by 86, 95, 83 and 82\u2005cm\u22121 in UiO\u201066, UiO\u201066\u2010NH2, UiO\u201066\u2010CuII and Zr\u2010DMTDC, respectively  mode was monitored to examine the displacement of bound CO2 by SO2  stretch corresponding to the bare and CO2\u2010loaded materials are approximately equal. Due to weak interaction between CO2 and the \u03bc3\u2010OH group, the bare \u03bc3\u2010OH band is not fully depleted but a new peak at 3643\u2005cm\u22121 appears and is assigned to the [OH\u22c5\u22c5\u22c5OCO] band , there is a steady change in the \u03bd(\u03bc3\u2010OH) region that includes new bands appearing in a similar manner to the pure SO2 experiment, indicating that bound CO2 does not impede SO2 adsorption . Upon 30\u2009% SO2\u2010loading, the characteristic [OH\u22c5\u22c5\u22c5OCO] band has fully disappeared showing that SO2 readily displaces bound CO2 in the pore as a result of stronger binding. Hence, selective capture of SO2 from a mixture of SO2/CO2 can be achieved as demonstrated in separation experiments. Furthermore, 40\u2009%, 45\u2009% and 50\u2009% SO2\u2010loadings fully displace CO2 in UiO\u201066\u2010NH2, Zr\u2010DMTDC and UiO\u201066, respectively . The competitive binding studies of SO2/CO2 further confirm enhanced SO2 binding in the decorated MOFs. The decreasing partial pressure of SO2 on full displacement of CO2 in UiO\u201066\u2010CuII, UiO\u201066\u2010NH2 and Zr\u2010DMTDC is consistent with that observed in static and dynamic adsorption studies.Upon stepwise dosing of the COIn situ INS, coupled with DFT calculations, enables the visualization of binding dynamics for SO2\u2010loaded Zr\u2010bptc. Seven major changes in the INS spectra were observed on the adsorption of SO2 in Zr\u2010bptc  was observed at 0.1\u2005bar and 298\u2005K. Furthermore, the captured SO2 in Zr\u2010bptc can be converted readily into fine chemicals, paving new pathways to \u201cwaste\u2010to\u2010chemicals\u201d technologies. In situ SXPD, microFTIR and INS studies, coupled with DFT calculations, unravel the molecular details of host\u2013guest binding that result in the enhancement of SO2 adsorption at low pressure in these materials. These studies confirm that control of pore environments is an important approach for improving the adsorption of SO2.Powerful drivers exist for the development of new regenerable sorbents for SO6(OH)8(OH)8(tcpt)2], [Zr6O4(OH)4(bptc)3\u2009\u22c5\u2009(SO2)5.8], [Zr6O4(OH)4(DMTDC)6\u2009\u22c5\u2009(SO2)13.1], [Zr6O4(OH)4(bdc)6\u2009\u22c5\u2009(SO2)7.7] and [Zr6O4(OH)4(bdc\u2212NH2)6\u2009\u22c5\u2009(SO2)8.1] are available free of charge from the Cambridge Crystallographic Data Centre .Additional crystallographic information, gas adsorption data, thermogravimetric analysis, density function theory (DFT) calculations and breakthrough data are available in the Supporting Information. The crystal structures of [ZrThe authors declare no conflict of interest.1As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re\u2010organized for online delivery, but are not copy\u2010edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors.Supporting InformationClick here for additional data file.Supporting InformationClick here for additional data file.Supporting InformationClick here for additional data file.Supporting InformationClick here for additional data file.Supporting InformationClick here for additional data file."}
{"text": "The revised version of"}
{"text": "The authors wish to make corrections to their paper , due to On page 2, in the third sentence of the second paragraph, reference 15 . On pageThe changes do not affect the scientific results. The manuscript will be updated and the original will remain online on the article webpage. We apologize for any inconvenience caused to the readers."}
{"text": "The authors regret having omitted a reference in the acknowledges section. It should read:Our work was supported by the Spanish R&D&I Programme with grants PID2019\u2013105471RB-I00, P18-RT-1060, and US-1380565  US/JUNTA/FEDER, UEThe authors would like to apologise for any inconvenience caused."}
{"text": "Stachybotrys chartarum with tyrosine kinase inhibition\u2019 by Yong Li et al., RSC Adv., 2017, 7, 7259\u20137267.Correction for \u2018Cytotoxic trichothecene-type sesquiterpenes from the sponge-derived fungus  The authors regret that compound 5 was incorrectly labelled in In addition, on page 7462 the sentence \u201cIn the present work, the absolute configurations of satratoxin G (6) and 2,4,12-trihydroxyapotrichothecene (14) were established by the analyses of the X-ray diffraction data using Flack parameters \u201d is corrThe Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Berrones-Reyes et al., RSC Adv., 2019, 9, 30778\u201330789.Correction for \u2018Quantum chemical elucidation of the turn-on luminescence mechanism in two new Schiff bases as selective chemosensors of Zn The correct email address is The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Journal of Healthcare Engineering has retracted the article titled \u201cAnalysis on Value of Applying Serum miR-144 and miR-221 Levels in Diagnosing Atherosclerosis\u201d [Following an investigation conducted by the Hindawi Research Integrity team , signifi"}
{"text": "After having been in contact with the authors, they agreed with the decision to retract the paper. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors' attention by a concerned reader that the data shown in one of the panels belonging to the flow cytometric experiments shown in Fig. 5C were strikingly similar to data appearing in different form in another article published by different authors. Owing to the fact that the contentious data in the above article were already under consideration for publication prior to its submission to"}
{"text": "DOI: 10.1039/D1RA04125H.Correction for \u2018Oxovanadium( The authors regret that there were two errors in the original version of the manuscript.3, should be VO(OEt)3. The superscript reference to footnote c remains correct.The third entry of Table 1, which originally read VO(Et)In addition, the structure of dimethylethylsilylimidazole in Table 2 in the original manuscript was incorrect. The correct structure is given here:The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "RSC Advances article due to concerns with the reliability of the data in the published article. The authors requested to retract this article because they admitted that the TEM characterization of the Fe3O4@NiO hierarchical microspheres in Fig. 4c was duplicated from the characterization of Fe3O4@NiAl-LDH microspheres in Fig. S4B from a J. Am. Chem. Soc. paper by Mingfei Shao et al. without permission.1 The authors would like to apologise to the authors of ref. The Royal Society of Chemistry, with the agreement of the named authors, hereby wholly retracts this Signed: Shouwei Zhang, Jiaxing Li, Jinzhang Xu and Xiangke WangDate: 11th August 2021Tao Wen was contacted but did not respondRSC AdvancesRetraction endorsed by Laura Fisher, Executive Editor,"}
{"text": "RSC Advances is publishing this expression of concern in order to alert our readers that we are presently unable to confirm the reliability of the data presented in the article.The Royal Society of Chemistry was contacted by a reader who raised concerns about the reliability of the data presented in Fig. 2, 3 and S7 of the paper. The authors are unable to provide raw data to corroborate their work.The Royal Society of Chemistry has asked the affiliated institution (Indian Institute of Technology Mandi) to investigate this matter and confirm the integrity and reliability of the data in Fig. 2, 3 and S7 of the paper. An expression of concern will continue to be associated with this manuscript until we receive information from the institution on this matter.Laura Fisher01/07/2022RSC AdvancesExecutive Editor,"}
{"text": "Retraction Note:J Exp Clin Cancer Res37, 202 (2018)https://doi.org/10.1186/s13046-018-0875-3The Editor-in-Chief has retracted this article because data presented in Figs. 2, 3 and 4 were duplicated from previously published articles. Specifically, a set of staining images in Fig. 2I had previously been published as Fig. 3E in . The act"}
{"text": "Furthermore, a problematic issue was also noted with the Kaplan-Meier plots in Fig. 3C on p. 6, where the units along the Oncology Letters has decided that this paper should be retracted from the Journal on account of the sharing of data and a lack of confidence in the presented results. The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Given the issue of the overlapping section of data and the difficulties associated with the presentation of the Kaplan-Meier plots, the Editor of"}
{"text": "Journal of Healthcare Engineering has retracted the article titled \u201cThe Effect of Acupuncture Combined with Aerobic Exercise for Coronary Heart Disease as Cardiac Rehabilitation\u201d [itation\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifi"}
{"text": "In our paper"}
{"text": "The Editors-in-Chief have retracted this article. After publication, concerns were raised regarding potential image duplication in the figures.In Fig.\u00a01b, the 0\u00a0ng\u2009+\u2009SB and 25\u00a0ng\u2009+\u2009SB group images appear to originate from the same sample (rotated 90 degrees);In Fig.\u00a01c, T\u03b2RII lane 3 and GAPDH lanes 2 and 3 appear highly similar to Fig.\u00a03d hUASMC p-Smad3 lane 1 and \u03b2-actin (both lanes), respectively;In Fig.\u00a04d, the images for the hUVEC and Scrambled hUVEC groups appear to contain overlap.Specifically:The authors have stated that these issues occurred due to errors in data storage. Additionally, they have been unable to provide the raw images of the western blots presented in Fig.\u00a01c. The Editor-in-Chief therefore no longer has confidence in the presented data.Jianzhong Xu has stated on behalf of all authors that none of the authors agree to this retraction."}
{"text": "In Ferris et\u00a0al.,Michael Kissick is employed by and has ownership interest in Accuray, Inc. John E Bayouth has ownership interest in MR guidance, LLC, which has business activity with a company that utilizes respiratory motion management . The remaining authors have no conflicts of interest to disclose."}
{"text": "RSC Advances article. The NMR spectra for compounds 3a\u20133k and 3s\u20133u in the ESI have been reproduced without permission from a Tetrahedron Letters paper by Fei Ling et al.1 The authors stated that as their 2,4,6-triarylpyridines products are known, they only characterised three of their compounds using 1H NMR and 13C NMR, which were identical to those reported in the literature. Therefore, the authors do not have full characterisation data for their published paper.The Royal Society of Chemistry hereby wholly retracts this Hongshe Wang opposes the retraction. Weixing Zhao, Juan Du, Fenyan Wei, Qi Chen and Xiaomei Wang were contacted but did not respond.RSC AdvancesSigned: Laura Fisher, Executive Editor, th June 2020Date: 16"}
{"text": "Retraction Note: BMC Med 10, 40 (2012)https://doi.org/10.1186/1741-7015-10-40The Chief Editor has retracted this article following an institutional investigation by the University of Wyoming due to concerns regarding data irregularities inconsistent with published conclusions.Specifically, the investigation found evidence of data irregularities and image reuse in Fig. 7K with previously published articles: Fig. 5 in , Fig. 9 Author Sara Babcock agrees to this retraction. Authors Jun Ren and Yingmei Zhang do not agree to this retraction. Author Haichang Wang has not responded to any correspondence from the editor or publisher about this retraction. The editor was not able to obtain a current email address for Authors Nan Hu and Jacalyn Maris."}
{"text": "The performance of auditory steady state response (ASSR) in threshold testing when recorded ipsilaterally and contralaterally, as well as at low and high modulation frequencies (MFs), has not been systematically studied.vs. contralateral) and modulation frequency (40\u00a0Hz vs. 90\u00a0Hz) on ASSR thresholds.To verify the influences of mode of recording  modulated at 40 and 90\u00a0Hz MFs were presented to the participants\u2019 right ear. The ASSR thresholds were then recorded at each test frequency in both ipsilateral and contralateral channels.Fifteen female and 14 male subjects (aged 18\u201330 years) with normal hearing bilaterally were studied. Narrow-band CE-chirpp\u00a0<\u00a00.05 by two-way repeated measures ANOVA), mean ASSR thresholds were then compared among four conditions  using one-way repeated measures ANOVA. At the 500 and 1000\u00a0Hz test frequencies, contra-40\u00a0Hz condition produced the lowest mean ASSR thresholds. In contrast, at high frequencies (2000 and 4000\u00a0Hz), ipsi-90\u00a0Hz condition revealed the lowest mean ASSR thresholds. At most test frequencies, contra-90\u00a0Hz produced the highest mean ASSR thresholds.Due to pronounced interaction effects between mode of recording and MF (Based on the findings, the present study recommends two different protocols for an optimum threshold testing with ASSR, at least when testing young adults. This includes the use of contra-40\u00a0Hz recording mode due to its promising performance in hearing threshold estimation. Auditory steady state response (ASSR) is an electrical potential evoked by periodic amplitude modulated and/or frequency modulated stimuli. Differently from conventional auditory evoked potentials, ASSR utilizes an objective threshold detection method, which provides clinicians and researchers a convenient way for estimating behavior hearing thresholds.The ASSR thresholds have been shown to be closely related to pure tone audiogram in various studies. In fact, ASSRs evoked by stimuli at 90 and 40\u00a0Hz modulation frequencies (MFs) show consistency with auditory brainstem response (ABR) and activity in the upper region of central auditory nervous system (CANS), respectively.6i.e., ipsilateral vs. contralateral) on ASSR have also been investigated. Van Maanen and StapellsThe effects of mode of recording , right-handed, with normal hearing in both ears (thresholds \u226415\u00a0dB HL from 500 to 4000\u00a0Hz) and without any record of head injuries and neurological disorders or any active ear pathology took part in the study. All of them agreed to voluntary participation by signing the written informed consent. Prior to testing, an ethical approval from the respective institution was obtained, in accordance with the Declaration of Helsinki (USM/PPP/JEPeM [245.3(5)]).To ensure normal hearing status, basic audiologic evaluations including otoscopy, admittance audiometry  and pure tone audiometry (Model AC 40 two-channel audiometer) were performed on all participants in a sound-treated room within the Audiology Clinic, University Hospital.\u00ae signals centered at 500, 1000, 2000, and 4000\u00a0Hz were used as the test stimuli. The chirp stimuli were designed to compensate for the cochlear delay and to produce a bigger response.ASSR thresholds were then recorded with a two-channel Eclipse system  and narrow-band CE-chirpi.e., ASSRs recorded in the right and left channels represented ipsilateral and contralateral conditions, respectively). The impedance of electrodes was maintained to be less than 3\u00a0k\u03a9 throughout the measurements.Four scalp electrodes were placed on the participant's head: non-inverting on the forehead, inverting on each mastoid, and ground on the cheek. For both ipsilateral and contralateral recordings, the insert earphone was placed only in the right ear  technique through the insert earphone. This technique offers a time-effective way for stimulus presentation, as four frequencies can be tested simultaneously. The measurement started with 40\u00a0Hz MF and was followed by 90\u00a0Hz MF recordings, as the participants were typically awake at the beginning of the testing. Nevertheless, during the 40\u00a0Hz ASSR measurements, the participants\u2019 state was closely monitored to ensure adequate wakefulness.For detecting the response in a quick and accurate manner, the ASSR Eclipse system utilized the \u2018Full Spectrum Detection Engine\u2019 method. With this method, amplitude and phase coherence components were combined, and responses from higher harmonics were also included in the detection algorithm. In comparison to the use of information only from the first harmonic, significantly higher response detection rates and shorter detection times were observed when all available responses (amplitude and phase) from first and higher harmonics were utilized.With the ASSR Eclipse device, at a particular intensity level, the response is considered present if it reaches an amplitude level that is within 95% confidence within the default time of 6\u00a0min. In the current study, the ASSR measurement started at 60\u00a0dB nHL of intensity. If the response was clearly detected (reached 95% confidence) sooner than the default time, the trial was stopped and the stimulus intensity was decreased by 10\u00a0dB. If the confidence of response was less than 50% during the first 3\u00a0min, the trial was stopped and the test was repeated at a similar level. If unclear response was still observed (<50% confidence), the trial was stopped and the stimulus intensity was increased by 5\u00a0dB. The measurements continued until ASSR threshold was obtained. The ASSR threshold was defined as the lowest intensity level that elicited response with 95% confidence in 6\u00a0min. At the threshold level, the measurements were repeated twice to confirm the test reproducibility. The ASSR threshold was obtained at each test frequency at different MFs and for both recording conditions. To avoid fatigue during the recording, 10\u00a0min of break was given to the participants between each trial.p\u00a0>\u00a00.05). For each test frequency, two-way repeated measures ANOVA (with mode of recording and MF as the factors) was performed to compare mean ASSR thresholds between ipsilateral and contralateral recordings, as well as between 40\u00a0Hz and 90\u00a0Hz MFs. To analyze the simple main effects , one-way repeated measures ANOVA was conducted to compare mean ASSR thresholds among the following conditions: ipsi-40\u00a0Hz, contra-40\u00a0Hz, ipsi-90\u00a0Hz, and contra-90\u00a0Hz. Prior to this, the Mauchly test was carried out to test the assumption of sphericity. For pairwise comparisons, Bonferroni correction was used. The statistical significance level was set at p\u00a0<\u00a00.05. All data were analyzed using the SPSS software v. 20 .For data analysis, both descriptive and inferential statistics were used. Mean and standard deviation (SD) were expressed as applicable. All the numerical data were found to be normally distributed as shown by Kolmogorov\u2013Smirnov test (Mean and standard deviation of ASSR thresholds for both recording modes at different MFs at specific test frequencies are shown in p\u00a0<\u00a00.05). Consequently, the interpretation of the main effects  can be misleading. To address this issue, one-way repeated measures ANOVA was carried out and the simple main effects were determined. At all test frequencies, Mauchly's test of sphericity revealed that the sphericity had not been violated (p\u00a0>\u00a00.05). Consequently, correction of the degrees of freedom was not required. i.e., ipsi-40\u00a0Hz, contra-40\u00a0Hz, ipsi-90\u00a0Hz, and contra-90\u00a0Hz) were found to be statistically different from each other at all test frequencies (p\u00a0<\u00a00.05).To confirm these descriptive observations, two-way repeated measures ANOVA was conducted; the statistical outcomes are shown in vs. contra-90\u00a0Hz\u2019, \u2018contra-40\u00a0Hz vs. contra-90\u00a0Hz\u2019, \u2018contra-40\u00a0Hz vs. ipsi-90\u00a0Hz\u2019 and \u2018contra-90\u00a0Hz vs. ipsi-40\u00a0Hz\u2019 conditions (p\u00a0<\u00a00.05). At the 1000\u00a0Hz test frequency, three conditions  produced statistically significant outcomes (p\u00a0<\u00a00.05). At both the 500 and 1000\u00a0Hz test frequencies, the mean ASSR thresholds were statistically different between contra-40\u00a0Hz and contra-90\u00a0Hz conditions. This supports the earlier observation that the contra-40\u00a0Hz condition produced the lowest mean ASSR threshold, while the contra-90\u00a0Hz condition revealed the highest mean ASSR threshold.The pairwise comparisons using Bonferroni correction at each test frequency was then performed; the results are shown in i.e., \u2018ipsi-40\u00a0Hz vs. contra-40\u00a0Hz\u2019) revealed a significant result (p\u00a0=\u00a00.027). Similarly, at the 4000\u00a0Hz test frequency, only one condition  produced a statistically significant outcome (p\u00a0=\u00a00.007).At the 2000\u00a0Hz test frequency, only one condition , lower ASSR thresholds at 40\u00a0Hz MF is possibly due to increased neural connections and binaural activities within these upper regions of CANS.At the 500 and 1000\u00a0Hz test frequencies, lower mean ASSR thresholds were observed at 40\u00a0Hz MF than at 90\u00a0Hz MF. In this situation, 40\u00a0Hz ASSR seems to be superior to 90\u00a0Hz ASSR, since it produced lower thresholds . The superiority of ASSR at low MF is consistent with the previous reports.vs. ipsi-90\u00a0Hz\u2019 and \u2018contra-40\u00a0Hz vs. contra-90\u00a0Hz\u2019) revealed insignificant statistical results at the 2000\u00a0Hz test frequency. These findings are inconsistent with the results of the previous studies that found lower ASSR thresholds with low MF stimuli.\u00ae stimuli for determining ASSR thresholds, whereas pure tones were utilized for recording ASSR thresholds in the previous studies. Since the stimuli used are different, some differences in the study outcomes would be expected.At 2000 and 4000\u00a0Hz test frequencies, the mean ASSR thresholds found in the present study were descriptively lower in ipsi-90\u00a0Hz condition than in ipsi-40\u00a0Hz condition. This difference was then found to be statistically significant only at the 4000\u00a0Hz test frequency . Both coIn the field of ASSR, literatures regarding the influence of ipsilateral and contralateral recordings are limited. In the present study, the majority of test frequencies  found no significant differences in ASSR threshold between ipsi-40\u00a0Hz and contra-40\u00a0Hz conditions. This suggests that the mode of recording has a subtle influence on ASSR thresholds evoked by low MF stimuli. This finding is in line with the study by Kaf and Daneshi.e., 65\u00a0dB SPL). As stated earlier, ASSRs recorded at threshold and supra-threshold levels might yield different outcomes.In contrast, for 90\u00a0Hz MF stimuli, ipsi-90\u00a0Hz condition produced statistically lower ASSR thresholds than that of contra-90\u00a0Hz condition at 500, 1000, and 2000 test frequencies. In fact, at these test frequencies, contra-90\u00a0Hz condition revealed the highest mean ASSR thresholds. Herein, a significant mode of recording effect on ASSR thresholds is noted for high MF stimuli. This result contradicts high MF findings in the study of Kaf and Danesh.n\u00a0=\u00a029). It is known that a larger sample size would increase the statistical power and the likelihood for rejecting the null hypothesis.The superiority of high MF ASSR in recording ipsilateral ASSR thresholds found in the present study is also inconsistent with the study by Small and Stapells.The present study, nonetheless, has some limitations. Firstly, due to the significant interaction effects, the specific effect of test frequency on ASSR thresholds is not determined. Herein, the occurrence of more complex interaction effects was anticipated if frequency is included as one of the factors. Secondly, the present study only tested the right ear of the participants. Since ASSR shows a pronounced laterality effect,An effort has been made to determine the influences of mode of recording and modulation frequency on ASSR thresholds in young adults. At low frequencies (500 and 1000\u00a0Hz), the 40\u00a0Hz MF produced lower ASSR thresholds than that of 90\u00a0Hz MF. At high frequencies (2000 and 4000\u00a0Hz), the ipsi-90\u00a0Hz produced the lowest ASSR thresholds. Based on the outcomes of the present study, the authors suggest two different protocols for an optimum threshold determination with ASSR in young adults. In the first protocol, the use of low MF stimuli for recording ASSR thresholds at low frequencies is suggested. At high frequencies, high MF stimuli are recommended. For all conditions, the recording mode is ipsilateral. In the second protocol, the use of low MF stimuli is recommended for determining ASSR thresholds at all test frequencies with contralateral recording.Research University (RU) Grant (1001/PPSK/812114), Universiti Sains Malaysia.The authors declare no conflicts of interest."}
{"text": "The authors regret their oversight in allowing these errors to be included in the paper, and also apologize to the readership for any inconvenience caused.The revised versions of"}
{"text": "Signal Transduction and Targeted Therapy 10.1038/s41392-022-00939-7, published online 25 April 2022Correction to: 1, the authors noticed several inadvertent mistakes occurring in Fig. TFE3 overexpression antagonized the NUPR1 KD-induced inhibition of OSCC cell proliferation and metastasis, were pasted and placed by mistake. The correct results should be as shown below. The authors apologize for these oversights and declare that these corrections do not affect the description, interpretation, or conclusions detailed in the original manuscript.In the process of checking the raw data"}
{"text": "Journal of Oncology has retracted the article titled \u201cDNA Damage Response Genes in Osteosarcoma\u201d [sarcoma\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifi"}
{"text": "Listeriosis outbreak caused by contaminated stuffed pork, Andalusia, Spain, July to October 2019\u2019 by Fern\u00e1ndez-Mart\u00ednez et al. published on 27 October 2022. The level of significance was noted as \u2018p values\u202f\u2009\u2265\u2009\u202f0.05\u2019 in the originally published version. This was corrected to \u2018p values\u202f\u2009\u2264\u2009\u202f0.05\u2019 on 28 October 2022. We apologise for any inconvenience this may have caused.A correction was made to the article \u2018"}
{"text": "DOI: 10.1039/d0na00055h.Correction for \u2018Highly modulated supported triazolium-based ionic liquids: direct control of the electronic environment on Cu nanoparticles\u2019 by Cristi\u00e1n Valdebenito  The corrected list of affiliations is as shown above.The authors regret that the one of the affiliations (affiliation The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "The Publisher retracts the cited article.Following publication, the publisher uncovered evidence that false identities were used in the peer-review process. The assignment of a fake reviewer was confirmed by an investigation, conducted in accordance with Frontiers\u2019 policies and the Committee on Publication Ethics (COPE) guidelines.The investigation also uncovered concerns about the presentation and validity of the data in the article that normally would have led to a rejection. When contacted, the authors failed to provide a data set that adequately supports the reported conclusions.The authors agree to this retraction.This retraction was approved by the Chief Editors of Frontiers in Cell and Developmental Biology and the Chief Executive Editor of Frontiers."}
{"text": "This article has been retracted: Oncotarget requested the original data for this paper to address concerns regarding image duplication. The authors were unable to retrieve the data. As a result, all authors have agreed to the retraction of this paper from Oncotarget. The University was notified about the issues with the paper.52960-52974. https://doi.org/10.18632/oncotarget.17674Original article: Oncotarget. 2017; 8:52960\u201352974."}
{"text": "Scientific Reports 10.1038/s41598-020-79851-5, published online 13 January 2021Retraction of: The Editors have retracted this Article. Following publication, concerns were raised about the rationale for the approach presented and the underlying reasoning. A post-publication review of the authors' mathematical arguments revealed a lack of clarity in the terms presented and inferences that are not adequately justified. The Editors therefore no longer have confidence in the conclusions presented.Nasrullah Khan and Muhammad Aslam do not agree to this retraction. P. Jeyadurga and S. Balamurali did not respond to correspondence relating to this retraction."}
{"text": "Following the publication of this article  and corr2 panel in Fig 2A and the cPLA2 panel in Fig 4A.The lower cPLAThe p38 panel in Fig 4C and the ATF2 panel in Fig 7A with colour levels adjusted.2 panel in Fig 4C, the GAPDH panel for c-Jun in Fig 6C, and lanes 3\u20135 of the GAPDH panel for cPLA2 (upper set) in Fig 6C.Lanes 2\u20134 of the GAPDH for cPLA2 in Fig 4C and the GAPDH panel for c-Fos in Fig 6C.Lanes 4\u20136 of the GAPDH panel for cPLAThe c-Jun and p-ATF2 panels in Fig 7B with colour levels adjusted.The corresponding author stated that multiple western blot experiments were performed and imaged at the same time. They acknowledged that errors occurred in the preparation of the figures and annotation of raw images, and apologized for these errors. The corresponding author accepted that the issues with the published figures cannot be fully resolved, and requested that the article be retracted.PLOS ONE Editors retract this article.In light of the concerns affecting multiple figure panels and the errors in the raw underlying data that question the reliability of these data, the ITL, CCL, LDH and CMY agreed with the retraction. SEC and YCH either did not respond directly or could not be reached."}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a satisfactory reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors\u2019 attention by a concerned reader that the cell migration assay images shown in Fig. 5 were strikingly similar to data appearing in different form in other articles written by different authors in different research institutions. Owing to the fact that the contentious data in the above article had already been published elsewhere prior to its submission to"}
{"text": "Commun., 2022, 58, 4060\u20134062, DOI: https://doi.org/10.1039/D2CC00173J.Correction for \u2018Cesium carbonate mediated C\u2013H functionalization of perhalogenated 12-vertex carborane anions\u2019 by Sergio O. Lovera  The authors regret that Alex L. Bagdasarian's name was spelled incorrectly in the original article. The correct author names are as presented here.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Chem. Chem. Phys., 2022, 24, 5269\u20135281, https://doi.org/10.1039/D1CP04393E.Correction for \u2018Transfer learned potential energy surfaces: accurate anharmonic vibrational dynamics and dissociation energies for the formic acid monomer and dimer\u2019 by Silvan K\u00e4ser  The authors would like to make a correction to The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Cancer Gene Therapy 10.1038/s41417-019-0098-6, published online 11 June 2019Retraction to: PUMA-KD Control and Cabozantinib groups. The raw data are no longer available. Therefore, the authors have lost confidence in the conclusions drawn in the study.The Editor-in-Chief has retracted this article at the authors\u2019 request. After publication, the authors became aware that some images were misused in Fig. 6d, which resulted in image overlap between the Shida Yang, Xiaobing Zhang, Huiling Qu, Bo Qu and Xiaoxue Yin agree to this retraction. Hongmei Zhao has not responded to any correspondence from the editor or publisher about this retraction."}
{"text": "In the original publication , there wThere was an error in the original publication . Two senA correction has been made to Abstract section, the seventh sentence and Section 3.5, third paragraph.2 42.68%; p heterogeneity = 0.12).The correct text of Abstract section, the seventh sentence is as follows: \u2026showing a tendency in favor of intervention group, even when the global results did not show statistically significant improvements .The correct text of the Section 3.5, third paragraph is as follows: Regarding the data presented, there seems to be a tendency in favor of IG in terms of improvement in QoL after exercise program intervention (pooled Cohen\u2019s d 0.11; 95% CI: \u22120.27 to 0.50; IThe authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "Computational Intelligence and Neuroscience has retracted the article titled \u201cAn Automated Toxicity Classification on Social Media Using LSTM and Word Embedding\u201d [bedding\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifiThe authors do not agree to the retraction."}
{"text": "The authors wish to make the following corrections to the published paper . They shIn the original publication, the Acknowledgments section \u201cAcknowledgments: The present work was funded through the Operational Program \u201cHuman Resources Development, Education and Lifelong Learning,\u201d project title \u201cMacromolecular architecture via hydrogen bonds. Synthesis, Characterization, Properties.\u201d (project code: 5006393).\u201d should be changed to \u201cAcknowledgments: This research is co-financed by Greece and the European Union  through the Operational Programme \u00abHuman Resources Development, Education and Lifelong Learning 2014\u20132020\u00bb in the context of the project \u201cMacromolecular architecture via hydrogen bonds. Synthesis, Characterization, Properties.\u201d (MIS 5006393).\u201dThe authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "Figure 1 as published. The chemical formulae of nucleolipids, i.e., DOTAU and diC16dT, did not display correctly, as the repeats of carbon atoms in the lipid chain (parenthesis and number of repeats) were missing. The corrected Figure 1 appears below. The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated.In the original publication , there w"}
{"text": "Specifically, Fig. 1 in the Mol Med Rep paper included the same histograms as those featured in Fig. 2 in the Circ Res paper; Fig. 2 in the Mol Med Rep paper contained data derived from Fig. 1 in the Circ Res paper; and Fig. 3, Fig. 4, Fig. 5 in both papers shared a substantial amount of the same data.An interested reader of an article published in the journal Following an internal investigation, the Journal was able to confirm that this accusation of plagiarism was well-founded. On those grounds, the Editor of Molecular Medicine Reports has decided to retract this paper. The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor deeply regrets the grievance that this matter has caused to the authors of the previously published article, and also any inconvenience caused to the readership of the Journal."}
{"text": "The authors regret that the funding information in the acknowledgements of the original article was incorrect. Natural Science Foundation of China (No. 21671114 and U1804113), should be \u201cNatural Science Foundation of China (No. 21671114 and U1804131)\u201d.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Computational and Mathematical Methods in Medicine has retracted the article titled \u201cMeta-Analysis of the Effectiveness and Safety of Intravenous Thrombolysis in Patients with Acute Cerebral Infarction\u201d [arction\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifiThe authors do not agree to the retraction."}
{"text": "Following the publication of the original article , the aut1: The authors noticed that the figure legend of Fig.\u00a04 should be added with positive HuNu staining (red) to provide additional clarification. The updated figure legend of Fig.\u00a04 is provided in this correction.2: Fig. 7D was mistakenly duplicated from 7C. The correct Fig.\u00a03: Fig. 8C was mistakenly duplicated from 8B. The correct Fig.\u00a02Second Department of Elderly Respiratory, Guangdong Provincial People\u2019s Hospital, Guangdong Academy of Medical Sciences, Guangdong Provincial Geriatrics Institute, Guangzhou, 510,080, China.\u201d4: The affiliation of the corresponding author is not accurate. The footnote on the first page should be changed to \u201cIt has been corrected after the authors double checked the original data. The results and conclusions concluded in this paper are still valid.Legend for figure 4:Fig. 4 Engraftment of SHED around the fistula and in the lung. A Surviving SHED (positive HuNu staining (red)) after transplantation around the fistula. SHED were found in both the I\u2011SHED group and the L\u2011SHED group. No SHED were observed in the I\u2011PBS and L\u2011PBS groups. B Surviving SHED (positive HuNu staining (red)) after transplantation in the lung. SHED were found in the I\u2011SHED group. However, no transplanted SHED were seen in the other groups."}
{"text": "At the time of publication, the author was affiliated to both \u201cDepartment of Cardiovascular Surgery, Japanese Red Cross Nagoya First Hospital, Nagoya, Japan\u201d and \u201cDepartment of Cardiac Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan\u201d."}
{"text": "In \u201cDevelopment of a Therapeutic Video Game With the MDA Framework to Decrease Anxiety in Preschool-Aged Children With Acute Lymphoblastic Leukemia: Mixed Methods Approach\u201d :e37079) the authors noted a few errors in In the originally published paper, the headings of subcolumns appeared as \u201cFRS score, range\u201d and \u201cFRS score, mean (SD).\u201d These headings have been corrected to \u201cRange\u201d and \u201cMean (SD),\u201d respectively. The sequence of footnotes was revised accordingly. The updated version of The correction will appear in the online version of the paper on the JMIR Publications website on October 5, 2022, together with the publication of this correction notice. Because this was made after submission to PubMed, PubMed Central, and other full-text repositories, the corrected article has also been resubmitted to those repositories."}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editor's attention by a concerned reader that certain of the cell invasion and migration assay data shown in Figs. 2C and 4C, and western blotting data shown in Fig. 3D were strikingly similar to data appearing in different form in several other articles by different authors at different research institutes, some of which have been retracted. Owing to the fact that the contentious data in the above article had already been published, or were already under consideration for publication, elsewhere prior to its submission to"}
{"text": "Chem. Chem. Phys., 2022, 24, 20258\u201320273, https://doi.org/10.1039/D2CP01041K.Correction for \u2018Optimisation of  The authors would like to make the following change in the Acknowledgements section of the published article.https://wrap.warwick.ac.uk/167703/\u2019\u2018Data for this study are provided as a supporting data set from the University of Warwick Research Datasets portal at https://wrap.warwick.ac.uk/166703/.\u2019 is amended to \u2018Data for this study are provided as a supporting data set from the University of Warwick Research Datasets portal at The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Oxidative Medicine and Cellular Longevity has retracted the article titled \u201cThe Favorable Effect of Mesenchymal Stem Cell Treatment on the Antioxidant Protective Mechanism in the Corneal Epithelium and Renewal of Corneal Optical Properties Changed after Alkali Burns\u201d [i Burns\u201d , due to i Burns\u201d  is duplii Burns\u201d . Additioi Burns\u201d  is duplii Burns\u201d . Figuresi Burns\u201d  are dupli Burns\u201d .The authors were asked for clarification, but did not satisfactorily address the concerns of the Editorial Board. The article is therefore being retracted due to concerns regarding the reliability of the data. Authors Dr. Jitka Cejkova and Dr. Cestmir Cejka are deceased and Dr. Peter Trosan did not respond to these concerns. The remaining authors agree to the retraction."}
{"text": "Escherichia coli planktonic and biofilm cultures\u2019 by Min Li et al., RSC Adv., 2017, 7, 40734\u201340744, https://doi.org/10.1039/C7RA06073D.Correction for \u2018Photodynamic antimicrobial chemotherapy with cationic phthalocyanines against  The authors regret that incorrect versions of The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Adeniyi\u2010Jones, Marc R. Gastonguay, Ana Ruiz\u2010Garcia, Gagan Kaushal, Walter K. Kraft, Clin Transl Sci. 2021;14:2171\u20132183. In the published version of the above article, the authors noticed that the surname of the sixth author was misspelled as Gagan Kushal, instead of Gagan Kaushal.The authors regret the error."}
{"text": "The authors regret that an incorrect grant number was shown in the Acknowledgements section of the published article. The corrected section should read:The authors gratefully acknowledge the Ministry of Higher Education Malaysia (MOHE) for the research project financial support through the Fundamental Research Grant Scheme (FRGS/1/2019/STG01/UM/02/7) and the University of Malaya.\u00a0The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors\u2019 attention by a concerned reader that certain of the data shown in the cell invasion assays in Figs. 2C and 5C were strikingly similar to data appearing in different form in other articles by different authors. Owing to the fact that the contentious data in the above article had already been published elsewhere, or were already under consideration for publication, prior to its submission to"}
{"text": "Retraction to: Cell Biosci (2018) 8:17https://doi.org/10.1186/s13578-018-0212-8The Editor-in-Chief has retracted this paper. After publication, concerns were raised around the similarity between the rightmost ACHN panel of Fig.\u00a04f and the TGF-B1\u2009+\u2009Celecoxib panel in Fig.\u00a05B in a previously-published article by different authors ["}
{"text": "Streptomyces sporoverrucosus\u2019 by Shreyans K. Jain et al., RSC Adv., 2013, 3, 21046\u201321053, https://doi.org/10.1039/c3ra42884b.Correction for \u2018Chrysomycins A\u2013C, antileukemic naphthocoumarins from  The authors regret that incorrect versions of The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Anal. At. Spectrom., 2020, 35, 320\u2013330, https://doi.org/10.1030/c9ja00331b.Correction for \u2018Precise measurement of selenium isotopes by HG-MC-ICPMS using a 76\u201378 double-spike\u2019 by Marie-Laure Pons  The authors regret an error in The authors also regret an error in the graphical abstract image. The correct graphical abstract image is as follows:The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "The authors have been informed of some errors that occurred in the published paper. The errors are listed as:\u2022A paragraph has been added to Materials and Methods section about blinding.\u2022The statistical test which has been used in tables I, II has been changed from chi-square test to Fischer exact test.\u2022The study results were re-analyzed, and some p-values were modified in tables.\u2022The last paragraph of discussion section has been removed.The authors wish to apologize for these errors. The online version of the article has been updated on May 30, 2022, and can be found athttp://dx.doi.org/10.18502/ijrm.v11i10.356."}
{"text": "Applied Bionics and Biomechanics has retracted the article titled \u201cMedical Data Analysis of Lumbar Disc Herniation Patients after Traditional Chinese Medicine Rehabilitation Intervention Lumbar Function Recovery\u201d [ecovery\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifiThe authors do not agree to the retraction."}
{"text": "RSC Advances and ref. 2O/ZnO nanoflake, ref. The authors regret considerable unattributed text, figure and data overlap between their article in RSC Advances article were re-used from ref. RSC Advances article were not published elsewhere.Both articles contain some unique data, however, Fig. 1\u20134 and Table 1 of the The corrected captions are shown below:2O/ZnO nanoflake. Reproduced from ref. Fig. 1 FT-IR spectrum of Cu2O/ZnO nanoflake. Reproduced from ref. Fig. 2 The XRD pattern of Cu2O/ZnO nanoflake. Reproduced from ref. Fig. 3 The SEM image of Cu2O/ZnO nanoflake. Reproduced from ref. Fig. 4 TEM image of Cu2O/ZnO nanoflake. Reproduced from ref. 1Table 1 Results of BET surface area measurements for CuThe Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "In the published article, there was an error. The numbers of the concentrations were mistaken.Results, Pharmacokinetics of GA metabolites in female and male EHBRs orally treated with GA, Paragraph 7. These sentences previously stated:A correction has been made to 1, 4.3\u00a0\u00b5M of 2, 6.6\u00a0\u00b5M of 3, and 166\u00a0\u00b5M of 4.\u201d\u201cThe concentrations of GA and its metabolites 12\u00a0h after oral administration of GA in female EHBRs were 3.2\u00a0\u00b5M of GA, 0.1\u00a0\u00b5M of 3MGA, 14\u00a0\u00b5M of and1, 4.1\u00a0\u00b5M of 2, 1.2\u00a0\u00b5M of 3, and 198\u00a0\u00b5M of 4.\u201d\u201cThe concentrations of GA and its metabolites 12\u00a0h after oral administration of GA in male EHBRs were 2.6\u00a0\u00b5M of GA, 1.2\u00a0\u00b5M of 3MGA, 102\u00a0\u00b5M of The corrected sentences appear below:1, 10\u00a0\u00b5M of 2, 2.0\u00a0\u00b5M of 3, and 208\u00a0\u00b5M of 4.\u201d\u201cThe concentrations of GA and its metabolites 12\u00a0h after oral administration of GA in female EHBRs were 2.7\u00a0\u00b5M of GA, 0.1\u00a0\u00b5M of 3MGA, 32\u00a0\u00b5M of and1, 8.2\u00a0\u00b5M of 2, 2.2\u00a0\u00b5M of 3, and 237\u00a0\u00b5M of 4.\u201d\u201cThe concentrations of GA and its metabolites 12\u00a0h after oral administration of GA in male EHBRs were 2.6\u00a0\u00b5M of GA, 1.6\u00a0\u00b5M of 3MGA, 177\u00a0\u00b5M of The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated."}
{"text": "This article has been retracted: In July of 2020, the Academic Committee of Jiangsu Normal University launched an investigation of this paper and requested that the major authors provide the original experimental records and data for verification. To date, however, the authors have failed to provide the requested documents. The committee has concluded that this paper violates academic integrity. In light of this, the paper is retracted.101345-101361. https://doi.org/10.18632/oncotarget.21167Original article: Oncotarget. 2017; 8:101345\u2013101361."}
{"text": "The authors regret that incorrect details were given for note 20 in the original article. The correct version of note 20 is given below.13, or more likely its enantiomer, was prepared in ref. 18 .It appears as if compound The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "The consequences of schizophrenia stigma are numerous and highly damaging to individuals, their families, the health care system and society. Mental health professionals (MHP) are considered to be one of the main sources of stigmatization.To identify the characteristics of MHP stigma in schizophrenia in comparison with other psychiatric disorders, the specificities of MHP compared with other social groups, and associated factors.Following PRISMA guidelines, we systematically searched multiple electronic databases for articles: (i) reporting original data published in English in peer-reviewed journals, (ii) reporting quantitative data with statistical analysis, (iii) assessing stigma in a broad sense, and (iv) including samples composed only of MHP.A total of 38 articles published from 1999 to 2019 and involving 10926 MHP fulfilled our inclusion criteria. Studies showed that schizophrenia is the most stigmatized mental illnesses in MHP, despite recent results suggesting that borderline personality disorder and substance abuse may be more stigmatized. In comparison with other social groups, MHP reported less dangerousness beliefs and more positive beliefs regarding pharmacological treatment. Nevertheless, results were less consistent regarding prognosis and desire for social distance. Age, education level, type of mental health profession, or length of practice were associated factors that showed inconsistent relations with stigma. Work setting and biological causal beliefs were more clearly associated with MHP stigma.These findings provide strong support for the need to conduct specific research on schizophrenia stigma in MHP and the importance of controlling for several variables to identify predictors of stigma.No significant relationships."}
{"text": "In situ monitoring of functional activity of extracellular matrix stiffness-dependent multidrug resistance protein 1 using scanning electrochemical microscopy\u2019 by Shuake Kuermanbayi et al., Chem. Sci., 2022, https://doi.org/10.1039/d2sc02708a.Correction for \u2018 The authors regret that an incorrect version of The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "N-glycans and unique recognitions by glycan-binding proteins\u2019 by Xuefeng Cao et al., Chem. Sci., 2022, 13, 7644\u20137656, https://doi.org/10.1039/D1SC05435J.Correction for \u2018Systematic synthesis of bisected  The authors regret that funding details were incorrect in the acknowledgements section of the original article. The corrected acknowledgements section for this article is shown below.AcknowledgementsThe work was supported by United States National Institutes of Health (NIH) awards . The work is partially supported by GlycoMIP, a National Science Foundation Materials Innovation Platform funded through Cooperative Agreement DMR-1933525 and NIH R24GM137782. The glycan microarray analysis software MotifFinder was developed under the support of NIH SBIR award R43GM131430 to JZ.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors\u2019 attention by a concerned reader that certain of the cell migration and invasion assay data shown in Fig. 5C were strikingly similar to data appearing in different form in other articles by different authors. Owing to the fact that the contentious data in the above article had already been published elsewhere, or were already under consideration for publication, prior to its submission to"}
{"text": "In the original version of thisarticle, the These errors are typographical andhave no effect on discussionand conclusions, as the correct equations were used in the data analysisto obtain Figures 3 and 5."}
{"text": "The authors regret that the original version of our paper, unfortunately, contained an incorrect picture in Figure The correction made in this erratum does not affect the original data and conclusions. The authors apologize for any inconvenience that the errors may have caused."}
{"text": "Retraction Note: Cancer Cell Int (2021) 21:501 https://doi.org/10.1186/s12935-021-02209-yThe Editors-in-Chief have retracted this article because the cell lines used in this study (HCT116 and SW480) were found by the authors to be contaminated with HeLa cells. As a result, the Editors-in-Chief no longer have confidence in the data.The authors Guan-Yu Yu and Yao Wang have not responded to any correspondence from the editor/publisher about this retraction. All other authors agree to this retraction."}
{"text": "Cassia occidentalis Linn. stem using liquid chromatography tandem mass spectrometry: application to its pharmacokinetic studies\u2019 by Mohammed Riyazuddin et al., RSC Adv., 2020, 10, 4579\u20134588. DOI: 10.1039/C9RA07482ACorrection for \u2018Simultaneous quantification of five biomarkers in ethanolic extract of  The authors regret that the one of the affiliations (affiliation d) was incorrectly shown in the original manuscript. The corrected list of affiliations is as shown above.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "After having been in contact with the authors, they agreed with the decision to retract the paper. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors\u2019 attention by a concerned reader that certain of the cell migration assay data shown in Fig. 2C were strikingly similar to data that had appeared in different form in another article by different authors. Owing to the fact that the contentious data in the above article had already been published elsewhere prior to its submission to"}
{"text": "The authors wish to make following corrections in this paper :In the published study, there was an error regarding the affiliation for \u201cKornelia Indykiewicz\u201d. In addition to affiliation 1, \u201cFaculty of Electronics, Photonics and Microsystems, Wroc\u0142aw University of Science and Technology, Janiszewskiego 11/17, 50-372 Wroc\u0142aw, Poland\u201d should also be acknowledged. Funding: This research has received funding from the European Union\u2019s Horizon 2020 research and innovation programme under the Marie Sk\u0142odowska-Curie grant agreement No 955626 and Nordic Programme for Interdisciplinary Research, grant 105121. K.I. and A.Y. acknowledge support from the FLAG-ERA program, grant DeMeGRaS.In the original publication , the funThe authors apologize for any inconvenience caused and wish to state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "This abstract has been withdrawn"}
{"text": "The lncRNA SNHG5\u2010mediated miR\u2010205\u20105p downregulation contributes to the progression of clear cell renal cell carcinoma by targeting ZEB1. Cancer Med. 2020; 9: 4251\u20134264. wileyonlinelibrary.com), has been retracted by agreement between the authors, the journal's Editor in Chief, Dr Stephen Tait, and John Wiley & Sons Ltd. The retraction has been agreed following concerns raised by a third party regarding duplicated panels in figures within the article. Following the concerns raised, an investigation by the journal team found that there were discrepancies between the raw data and published images across several figures, including 6B, 2E, 5B, 3D, 5D, and 5F. The authors were unable to provide a satisfactory explanation for these discrepancies. The authors and the editors no longer have confidence in the results and conclusions.The above article, published online on April 12, 2020 in Wiley Online Library ("}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a satisfactory reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors\u2019 attention by a concerned reader that certain of the cell migration assay data shown in Figs. 3B and 5C were strikingly similar to data that had appeared in different form in other articles by different authors. Owing to the fact that the contentious data in the above article had already been published elsewhere, or were already under consideration for publication, prior to its submission to"}
{"text": "Computational and Mathematical Methods in Medicine has retracted the article titled \u201cApplication of Magnetic Resonance Imaging of Patients with Concussion in Clinical Emergency\u201d [ergency\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifiThe authors agree to the retraction."}
{"text": "The corrected mCherry and Gad1, Gad2 mRNA in the VTA and SN in cells with and without active Pax5 expression (Pax5 expression also originate from Pax5-expressing progenitor cells.\u201d The errors appear in print and in PDFs downloaded before December 1, 2022.The authors regret that in the original version of pression , demonst"}
{"text": "Scientific Reportshttps://doi.org/10.1038/s41598-021-97344-x, published online 08 September 2021Retraction of: The Editors have retracted this Article. Following publication, concerns were raised about the rationale for the approach presented and the underlying reasoning. A post-publication review of the authors' mathematical arguments revealed a lack of clarity in the terms presented and inferences that are not adequately justified. The Editors therefore no longer have confidence in the conclusions presented.Muhammad Aslam does not agree to this retraction."}
{"text": "We introduce the Astronomy New Talent collection, a collection of invited papers by tomorrow's leaders in astronomy and astrophysics. This collection showcases the strength of some of the research funded by the Royal Society. Comprising both research articles and review papers, this collection is a continuation of the series of commissioned New Talent collections which started with the Chemistry New Talent collection , which hThe authors published within this collection are recent awardees of a Royal Society University Research Fellowship (URF) , Newton We hope that readers of the journal will explore this collection and enjoy reading these pieces as much as we did. Royal Society URF Grant Kennedy, at the University of Warwick, investigates the origin and frequency of warm dust in the so-called \u2018habitable-zones\u2019 around stars . KatheriWe look forward to growing and expanding this collection from more contributors who are funded by the Royal Society. This collection highlights some of the exciting work from tomorrow's leaders in the field who are delving into the most pertinent questions within astronomy.https://royalsocietypublishing.org/topic/special-collections/astronomy-new-talent [These papers are all curated at w-talent ."}
{"text": "This abstract has been withdrawn."}
{"text": "In the article titled \u201cHD-13 Induces Swine Pneumonia Progression via Activation of TLR9\u201d [This work was supported by grants from the Scientific Research Project of Jiangsu Agri-animal Husbandry Vocational College (NSF201903)."}
{"text": "Due to a production error, an incorrect Funding statement was provided in which the funding number was omitted by mistake.The Funding statement has now been corrected to:\u201cThis study was supported financially by Hongta Tobacco (Group) Co. Ltd., Yuxi (2020YL04).\u201dMoreover, the old Funding statement has been moved to the Conflict of Interest statement, which now reads as follows:\u201cAuthors JL, JW, JY, and YT were employed by Hongta Tobacco (Group) Co. Ltd.The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.The authors declare that this study received funding from Hongta Tobacco (Group) Co. Ltd. The funder had the following involvement in the study: sample collection, analysis, and field investigations.\u201dThe publisher apologizes for these mistakes. The original version of this article has been updated."}
{"text": "Bioscience Reports article with regards to two of the images, Figures 5 and 6. A similar region of the Fig.5C Fasudil (5ug/ml) panel has been noted in the FSD-C10 (15ug/ml) panel (region rotated 180 degrees), along with similar bands being identified in the Fig.6 Western blots (the EAE and Fasudil lanes of panels 6A and 6D appear as the Fasudil and FSD-C10 bands of 6C). The authors have cooperated with the Bioscience Reports Editorial Office and have offered explanations for the duplicated regions, including that one of the lanes was erroneously removed from the western blots whilst compiling the figures. They have stated that the duplicated region  for Figure 5 could also have been due to errors whilst putting together the figures. The authors are currently searching for the original data to correct the images; however, given the age of the article, they have yet to be able to source the data. The authors state that the results of their experiments are unaffected by these issues, and as no further issues have been identified by the Editorial Office, the article will remain published with an Expression of Concern to alert readers to the duplicated regions.The Editorial Office has contacted the authors of this"}
{"text": "The corrected 1) The authors would like to correct mistakes in the title paper \u2019.\u2018Then, the rate of racemization of the methyl (3) In the References section the title of reference [17] contains the misspelled word: \u201cStom\u201d. It should be: \u201cAtom\u201d.The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. The original publication has also been updated."}
{"text": "The authors wish to make the following corrections to this paper :\u22122 s\u22121 (nanomole m\u22122 s\u22121), instead of \u00b5mol m\u22122 s\u22121 (micromole per square meter and second). A correction has been made to: 2. Materials and Methods, 2.2. VOC Sampling Method.There was an error in the original publication. The values of emission should be expressed as nmol m\u22122 s\u22121).The VOC emission rates are referred to as the units of surface area (nmol m\u22122 s\u22121 (nanomole m\u22122 s\u22121), instead of \u00b5mol m\u22122 s\u22121 (micromole per square meter and second). The corrected figures appear below. The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated. In the original publication, there was a mistake in"}
{"text": "RSC Advances article as recent recalculations on the data have shown that the results in the paper are unreliable.The Royal Society of Chemistry hereby wholly retracts this 3 in the C-AFM structure is inaccurate. The authors have also recalculated the energies of the FM, A-AFM, C-AFM and G-AFM structures and found that, although the C-AFM phase is the lowest energy structure, the energy difference values of the FM, A-AFM and G-AFM relative to C-AFM are inaccurate in the paper. In addition, the authors found that the structural data for BiVO3 with Pmna and C2/C structures in Table 1 is incorrect.The original calculation of the DOS (density of states) of BiVOThe recalculated results mean that the conclusions of the published paper are now unreliable; therefore, the article is being retracted to protect the accuracy and integrity of the scientific record.The corresponding author, Meng-Qiu Cai, agreed to retract the article, but did not respond to any correspondence regarding the wording of the retraction notice. The co-authors, Biao Liu, Li-Juan Wu, Yu-Qing Zhao and Lin-Zhi Wang, were contacted but did not respond.RSC AdvancesSigned: Andrew Shore, Executive Editor, th April 2019Date: 10"}
{"text": "Although tremendous strides have been made in the participation of women in medicine, female continues to be underrepresented in leadership positions and higher-level academic medicine. An important factor in determining career advancement in academic medicine is the quality and quantity of an individual\u2019s scholarly publications. To date, no study has looked at female authorship in gastroenterology (GI) randomized control trials (RCTs), which remains the gold standard for evaluating intervention effectiveness.The primary outcome is to assess female authorship in gastroenterology randomized control trials from 2011 to 2021, and the secondary outcome is to assess female authorship within GI subspecialty RCT publications.In this observational study, the gender of the first and last author of gastroenterology RCTs from January 1, 2011 to December 31, 2021 was assessed. Python (v3.8.12) was used to extract publication data from PubMed. A validated algorithm, genderize.io, was used to determine gender. Author first names that cannot be determined by the algorithm were manually searched on publicly-available profiles.A total of 5690 original gastroenterology RCTs were included from January 1, 2011 to December 31, 2021. The gender of the first and senior authors of the papers was determined for 5668 (99.6%) first authors and 5656 (99.4%) senior authors. Overall, 1937 (34.1%) of the first authors and 1138 (20.0%) of senior authors were female.There was an increase in the proportion of female first authors over the past decade, from 25.4% in 2011 to 37.8% in 2021 (p<0.05). For senior authors, there was a more gradual increase in female authorship from 14.2% in 2011 to 21.6% in 2021 (p<0.05). Within GI subspecialties, 612 RCTs were included for inflammatory bowel disease, 1143 RCTs were included for hepatology, and 1856 RCTs were included for therapeutic endoscopy from January 1, 2011 to December 31, 2021. Further analysis will be performed to determine the gender trend for GI subspecialties.Female authorship in gastroenterology RCTs has increased from 2011 to 2021, although the rate of senior authorship has increased to a slower extent compared to first authors. Across all years, female authorship in gastroenterology RCTs has been lower than males.NoneNone Declared"}
{"text": "Journal of Healthcare Engineering has retracted the article titled \u201cStudy on Toll-Like Receptor 2-Mediated Inflammation-Induced Familial Hypertension Combined with Hyperlipemia and Its Mechanism\u201d [chanism\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifiThe authors disagree with the retraction."}
{"text": "Environ HealthIns. 2021: 1-2.Smith LE, Potts HWW, Aml\u00f4t R, Fear NT, Michie S and Rubin GJ. COVID-19 and ventilation in thehome; investigating peoples\u2019 perceptions and self-reported behaviour (the COVID-19 RapidSurvey of Adherence to Interventions and Responses [CORSAIR] study) In the above-mentioned article, the authors have noticed some errors. There have been someerrors with the datasets delivered to the authors. There was a problem concerning the variabledenoting responder ID. For one panel used, all respondents were assigned unique IDs each timethey completed a survey, regardless of whether they had previously completed the survey.Therefore, repeat respondents were not appropriately identified. This affected data in waves 8to 57 (inclusive). The authors have since worked with the market research companies to rectifythis problem. The previously published manuscript states that \u201c10,207 responses from 10,199participants\u201d were used. The corrected figures are 10,207 responses from at least 10,152participants.This change does not affect the results nor conclusions in the manuscript.The online files have been updated."}
{"text": "H)-ones\u2019 by Vahid Khakyzadeh et al., RSC Adv., 2021, 11, 22751\u201322755. DOI: 10.1039/D1RA03769BRetraction of \u2018Boric acid in magnetized water: clean and powerful media for synthesis of 3,4-dihydropyrimidin-2(1 RSC Advances article. Although we maintain that the results obtained in distilled water are accurate, and believe that further experiments will confirm our conclusions, following discussions between the authors and the Royal Society of Chemistry, we have determined that the evidence presented regarding magnetised water in this paper is insufficient to support the conclusions and needs further investigation. We are therefore retracting the paper to maintain the validity of the scientific record. The Royal Society of Chemistry apologises for the fact that these concerns were not identified during the peer review process.We, the named authors, hereby wholly retract this ,a, Ahmad Reza Moosavi-Zareb, Sahra Sheikhaleslamia, Amir Ehsania, Salbin Sediqia, Mohammad Rezaei-Goharb and Zahra JaliliancSigned: Vahid Khakyzadeh*th August 2021.Date: 27RSC Advances, 27th, August 2021.Retraction endorsed by Laura Fisher, Executive Editor,"}
{"text": "Cell Death & Disease 10.1038/s41419-022-04678-z, published online 15 March 2022Retraction Note to: Figure 1D (panel D3) shares features with Fig. 1D (panel D4), as well as Fig. 2D (panel NaHS)Figure 2C (panel LX-2+PPG) shares features with Fig. 4C (panel Si + LX-2)Figure 2C (panel PPG) shares features with Fig. 4C (panel Si)Figure 5D (Cytoplasm panel p-JunB) overlaps with Fig. 5E (Cytoplasm panel p-JunB)The Editors-in-Chief have retracted this article because there is overlap within some of the images or data. In particular:In addition, Fig. 1D (panels D3 and D4), as well as Fig. 2D (panel NaHS) appear to have an irregularity within the image.As a result, the Editors-in-Chief no longer have confidence in the veracity of these data.Huiguo Ding agrees with the retraction but not with the wording of the retraction notice None of the other authors has responded to correspondence from the publisher about this retraction."}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors\u2019 attention by a concerned reader that certain of the cell invasion and migration assay data shown in Figs. 2C and 5C were strikingly similar to data appearing in different form in other articles by different authors. Owing to the fact that the contentious data in the above article had already been published elsewhere, or were already under consideration for publication, prior to its submission to"}
{"text": "A peripheral blood film revealed marked thrombocytosis with micromegakaryocytes and giant platelets  showed leucocyte, 12.80 \u00d7 10Jun Ooi wrote the paper, and Jun Ooi and Tomonori Sato performed the research.The authors declare that they have no conflict of interest.Informed consent was obtained from our patient included in this article."}
{"text": "Applied Bionics and Biomechanics has retracted the article titled \u201cCountermeasures for the Development of Data Integration of the Internet Ice and Snow Tourism Industry under the Background of Artificial Intelligence\u201d [ligence\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifi"}
{"text": "Following the publication of this paper, when reviewing the previous research projects, the authors realized that an error was made in the assembly of Figure"}
{"text": "The authors conceded that there was partial duplication between the images shown in Fig. 7B and F, although they were unable to access the related raw data as the experiments had been performed almost 10 years ago. Secondly, the authors informed the Editor that the corresponding author did not know he was on the author list at the time of submission.Although the authors' were granted permission to publish the Corrigendum, the Editor now considers that the paper should be retracted on account of the uncertainties in the presented revised data and the authors' admission concerning the corresponding author. Therefore, this paper has been retracted from the Journal. The authors are in agreement with the decision to retract the article. The Editor apologizes for any inconvenience caused."}
{"text": "Dear editor,1. Recently, we have demonstrated that atrial cardiomyocytes express ionotropic glutamate receptors (iGluRs) in high abundance, inhibition of which can significantly reduce the incidence of AF and effectively block AF progression in an experimental AF model using isolated rat hearts2. However, to date, none of medicines targeting iGluRs has been prescribed in clinical AF treatment. Memantine is a commonly used drug in clinic for the treatment of Alzheimer\u2019s disease by antagonizing iGluRs in neurons3. We therefore hypothesized that memantine may also exert an effect against AF by blocking iGluRs in atrial cardiomyocytes.Atrial fibrillation (AF), the most common sustained cardiac arrhythmia, can lead to severe consequences such as heart failure and stroke4. As shown in Fig. First, we assessed the effect of memantine on the prevention and termination of AF. To examine the preventive effect of memantine on AF, we constructed three in vitro rat AF models, covering three common clinical types of AF, i.e., stretch-induced AF, cholinergic AF and ischemia-induced AF3, but whether it targets iGluRs of atrial cardiomyocytes is still unknown. To answer this question, we first measured the effect of memantine on iGluR-gated currents  in atrial cardiomyocytes. As shown in Fig. 2+ entry-induced Ca2+ overload5, and memantine can alleviate Ca2+ overload by suppressing the iGluRs6. Thus, our second experiment assessed the effect of memantine on Ca2+ leakage in atrial cardiomyocytes from the AF rats, showing 100\u2009\u03bcM memantine significantly decreased the Ca2+ spark frequency  and atrial reentry8. To evaluate the role of memantine in these Ca2+ leakage-mediated events, we performed optical mapping which showed that 100\u2009\u03bcM memantine reduced not only the incidence of ectopic activity (from 87.5 to 10%) in the isolated rat atrial myocardium subjected to 5\u2009Hz pacing and hypoxia, but also the incidence of reentry (from 80% to 9.1%) in the isolated atrial myocardium from the AF rats , one of the important sources of triggered activity or ectopic activity10. Based on this, we explored whether memantine affects DADs of atrial cardiomyocytes from the AF rats. Our patch-clamp data revealed that 100\u2009\u03bcM memantine did decrease the percentage of atrial cardiomyocytes with DADs (from 80% to 16.6%) in rat atrial cardiomyocytes challenged with 2\u2009Hz pacing stimulation  In the central nervous system, memantine targets neuronal iGluRsats Fig. . (4) Ca2ion Fig. . This seFinally, we evaluated the potential effect of memantine on aberrant electrophysiological events associated with AF in human with human induced pluripotent stem cell-derived atrial cardiomyocytes (iPSC-ACMs). By using a multielectrode array, we revealed that 50\u2009\u03bcM memantine effectively decreased the percentage of cells with arrhythmic events from 93.8% to 21.9% Fig. . The pat3. For the first time, we here showed the beneficial effects of memantine on animal AF models. The new application of old medicines may greatly shorten the process of clinical drug development. We expect that memantine will eventually be clinically proven to be effective in the prevention and termination of AF, however, for the first step, clinical trials of memantine for AF are urgently needed.In summary, memantine can effectively prevent and terminate AF by blocking endogenous iGluRs in atrial cardiomyocytes, providing a new strategy for the clinical treatment of AF. Memantine has been widely prescribed for the treatment of Alzheimer\u2019s diseaseSupplementary information"}
{"text": "Sci., 2019, 10, 976\u2013982, https://doi.org/10.1039/C8SC04892D.Correction for \u2018Visible-light-mediated Minisci C\u2013H alkylation of heteroarenes with unactivated alkyl halides using O The authors regret that the regioselectivity of product 36 in The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "There is an error in the Correction published on April 23, 2019. The Correction should have also included the following text:Posidonia australis meadows declined by 0.2\u201340% total area at 11 of 14 study sites .\u201d\u201cIn the Results subsection of the Methods, there is an error in the first sentence. The correct sentence is:"}
{"text": "The authors regret that an incorrect grant number was shown in the Acknowledgements section of the published article. The corrected section should read:This work is supported by the Natural Science Foundation of Tianjin [No. 18JCQNJC06000] and the Youth Innovation Foundation of Tianjin University of Science and Technology [No. 2016LG16].The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "The published article incorrectly indicates four corresponding authors. The two corresponding authors should be Jin-wu Yan and Lei Zhang. In addition, a link to the equal contribution footnote, confirming that Yong-jun Wang and Jing-gong Liu contributed equally to the work, is missing in the published article. These errors are corrected herein.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Bioscience Reports at the request of the authors as they have been unable to replicate the results found in this study, hence the authors feel that the conclusions drawn are inaccurate. The Editor-in-Chief and Editorial Board agree with the Retraction.This article is being retracted from"}
{"text": "This article has been retracted: Oncotarget requested the original data for this paper to address concerns regarding image duplication. The authors were unable to retrieve the data. As a result, all authors have agreed to the retraction of this paper from Oncotarget.39756-39792. https://doi.org/10.18632/oncotarget.5476Original article: Oncotarget. 2015; 6:39756\u201339792."}
{"text": "Retraction Note: J Exp Clin Cancer Res 38, 104 (2019)https://doi.org/10.1186/s13046-019-1098-yThe Editor-in-Chief has retracted this Article. After publication, concerns were raised regarding overlapping panels in Figs. 6d and 7c. The authors addressed this by publishing a Correction . HoweverThe Editor-in-Chief therefore no longer has confidence in the presented data.None of the authors have responded to any correspondence from the publisher about this retraction notice."}
{"text": "Page 1: This article was published on 17 November 2021 with David H. Evans missing from the byline. The byline was updated in the version posted on 11 February 2022.Volume 9, no. 3, e00886-21, 2021,"}
{"text": "The authors apologize for any inconvenience it may cause."}
{"text": "The authors would like to draw your attention to their revised Acknowledgments, which are as follows:"}
{"text": "Medicine, is being retracted at the authors\u2019 request due to concerns about potential overlap with other publications.The article \u201cTraditional Chinese medicine intervention for autism spectrum disorders: A protocol for systematic review and network meta-analysis\u201d, which appeared in Volume 101, Issue 9 of"}
{"text": "The authors regret to inform that during the final submission of the figures in this manuscript's publication, the liver histopathological image of the Silymarin 100 group detected by hematoxylin-eosin (H&E) staining in Fig. 3(B) was duplicated by mistake when we laid out the images. The image for the Silymarin 100 group in Fig. 3(B) was inadvertently replaced with the image of another group carried out in the same batch. Nevertheless, we confirm that this mistake did not influence the research results and scientific conclusions of the article in any way.In the corrigendum Figure, we have provided a correct image for the Silymarin 100 group in Fig. 3(B). The only change in the panel of Fig. 3(B) is the Silymarin 100 group, the rest of the figure is identical to the published version. The authors would like to apologize for this oversight and for any confusion that it has caused.The incorrect version for Fig. 3(B):Fig. 3. Effects of GLE intervention on the liver histopathological features in mice with excessive alcohol consumption.The corrected version for Fig. 3(B):Fig. 3. Effects of GLE intervention on the liver histopathological features in mice with excessive alcohol consumption."}
{"text": "Journal of Healthcare Engineering has retracted the article titled \u201cConstruction of the \u201cInternet Plus\u201d Community Smart Elderly Care Service Platform\u201d [latform\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifi"}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors\u2019 attention by a concerned reader that certain of the cell migration assay data shown in Fig. 3A and B and Fig. 5D were strikingly similar to data that had appeared in different form in other articles by different authors (in addition to the apparent duplication of some of these data within this paper itself). Owing to the fact that the contentious data in the above article had already been published elsewhere, or were already under consideration for publication, prior to its submission to"}
{"text": "Retraction Note: BMC Surgery (2022) 22:271https://doi.org/10.1186/s12893-022-01720-xThe Executive Editor has retracted this article since the authors were unable to provide the ethics approval documentation for this study. All authors agree to this retraction."}
{"text": "Journal of Healthcare Engineering has retracted the article titled \u201cTreatment Effect of Mometasone Furoate Cream on Lichen Sclerosus et Atrophicus of External Genitalia in Boys and Its Correlation with Toll-Like Receptor 4 and Myeloid Differentiation Factor 88\u201d [ctor 88\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifiThe authors do not agree to the retraction."}
{"text": "An magn"}
{"text": "The authors would like to apologize for any inconvenience caused to readers by this correction. Replacing this figure will not affect the results or conclusions of the paper. The manuscript will be updated and the original will remain online on the article webpage, with reference to this correction.After careful examination, we found that the structures  of compo"}
{"text": "ChemComm paper.1 Although the ChemComm article was cited as ref. 15b, and here as ref. The authors regret that it was not clear in the original article that part of the graphical abstract image had been reproduced from the graphical abstract of an earlier The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "The authors wish to make the following corrections to this paper :Error in FigureThe replacement of panels d and e in Additionally, the authors also wish to publish the corrected panel e of The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors\u2019 attention by a concerned reader that certain of the data shown for the cell migration and invasion assays in Figs. 2C, 4C and 5C were strikingly similar to data appearing in different form in other articles by different authors. Owing to the fact that the contentious data in the above article had already been published elsewhere, or were already under consideration for publication, prior to its submission to"}
{"text": "Panel E of"}
{"text": "Subha Madhavan (S.M.) and Anas Belouali (A.B.) were not included as authors in the published article . The corS.M. and A.B. made substantial contributions to this manuscript. S.M. and A.B. contributed to data curation and cleaning, database maintenance, and editing and review of the manuscript. S.M. also contributed to funding acquisition.The affiliation 8 is newly added:8\u2003Innovation Center for Biomedical Informatics, Georgetown University Medical Center, Washington, DC 20007, USAThe affiliation 9 should be updated to:9\u2003Department of Surgery, University of Florida, Gainesville, FL 32610, USAAuthor Contributions: Conceptualization, D.Z. and D.B.; methodology, D.Z.; software, D.Z.; validation, D.Z., N.J.S., S.A., A.L.P., M.B.A. and D.B.; formal analysis, D.Z.; investigation, D.Z. and N.J.S.; resources, S.M., A.B. and M.B.A.; data curation, S.M., A.B., N.J.S. and M.B.A.; writing\u2014original draft preparation, D.Z.; writing\u2014review and editing, D.Z., N.J.S., M.C., M.B., M.T.S., S.A., A.L.P., S.M., A.B., M.B.A. and D.B.; visualization, D.Z.; supervision, M.B.A. and D.B.; funding acquisition, S.M. and M.B.A. All authors have read and agreed to the published version of the manuscript.The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. The original article has been updated."}
{"text": "Following the publication of this article , concernIn Fig 4C, there appear to be repetitive elements in the background within and between lanes 5\u201310 when color levels are adjusted.In Fig 5B, there appear to be repetitive elements in the background of lanes 2\u20133 when color levels are adjusted.\u25cb Lanes 1 and 2 of the \u03b2-catenin panel in Fig 7B and the \u03b2-catenin panel in Fig 8C flipped vertically.\u25cb Lanes 1 and 2 of the KCTD1 panel in Fig 7B and the KCTD1 panel in Fig 8C.\u25cb Lanes 1 and 2 of the \u03b2-actin panel in Fig 7B and the \u03b2-actin panel in Fig 8C flipped vertically.In Figs 7B and 8C, the following bands appear similar:The corresponding author acknowledged that Figs 4C and 5B contain repetitive elements in the background and stated that the figures were adjusted in error. They provided raw image data underlying Figs 4C and 5B and repeat experiments. The raw data did not resolve the concerns regarding repetitive elements which question the integrity of these data, and the journal does not consider alternative experiment data to be sufficient to address these concerns.The corresponding author stated that the results in lanes 1\u20132 of Fig 7B and the results in Fig 8C represent the same experimental conditions. Furthermore, the corresponding author clarified that the \u03b2-catenin and \u03b2-actin blots in Fig 8C were inadvertently flipped across the horizontal axes during figure preparation.PLOS ONE Editors retract this article.In light of the concerns affecting Figs 4C and 5B that question the integrity of these data, the XL, CC, FW, WH, and XD did not agree with the retraction and stand by the article\u2019s findings. All other authors either did not respond directly or could not be reached."}
{"text": "DOI: 10.1039/c9ra10156jCorrection for \u2018Biological behavior exploration of a paclitaxel-eluting poly- The authors regret that incorrect details were given for ref. 52 in the original article. The correct version of ref. 52 is given below as et al. found that\u2026\u201d on page 15086, the corrected sentence should read as follows: \u201cShi et al. found that a magnesium-based drug delivery system had a stronger long-term inhibitory effect on the proliferation of SMCs cultured in vitro compared to stainless steel, which may be related to the degradation of magnesium alloy matrix greatly accelerating and improving the pharmacokinetics of drug release in vitro.52\u201dIn the sentence beginning \u201cStephen The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Supporting Information) was erroneous, and the correct figures are shown here and in theupdated SI file; the figure captions remain the same. These correctionsdo not in any way affect the discussion and conclusions presentedin the paper.The conductivity axis in"}
{"text": "Applied Bionics and Biomechanics has retracted the article titled \u201cApproaches to Federated Computing for the Protection of Patient Privacy and Security Using Medical Applications\u201d [cations\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifiThe authors do not agree to the retraction."}
{"text": "The authors regret that there was an error in the sentence in lines 14\u201318 in the right column on page 16813 of the original article, in the sub-section \u201cSensing mechanism\u201d. The text originally read: \u201cTo verify the mechanism of AuNPs aggregation in the presence of Ap, the following experiment was carried out: after the reaction nanosensor with AP, the final product was centrifuged and washed many times to purify and separate from the synthesis media.\u201d This sentence should read: \u201cTo verify the mechanism of AuNPs aggregation in the presence of Ap, the following experiment was carried out: after the preparation of the nanosensor, the final product was centrifuged and washed many times to purify and separate from the synthesis media.\u201dThe Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "The authors regret an error in the data processing leading to a swap of information in This mistake also led to a misinterpretation of the literature data reported in this table in the discussion. Indeed, the sentence beginning on line 25 of page 12529 (at the start of the penultimate paragraph of the Introduction section) is incorrect; the corrected text is:\u22123 mol L\u22121 (ref. 26)) and \u2264200 nm agglomerates at lower concentrations\u201d.\u201cThese colloids correspond to 1\u201320 nm particles at high silicate ion concentrations  is also incorrect; the corrected text is:4,24,25\u201d\u201cIt is worth noting that no evidence of particle agglomeration was observed; that result is consistent with the results obtained for the other actinide silicate colloids above the silicic acid mononuclear wall.These errors do not affect the overall conclusions of the paper.The authors would like to apologize for these errors and any consequent inconvenience caused.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "T proposed,\u2020 it should read \u0394T = Hv/Cp. While this expression is dimensionally correct and gives rise to the definition of the Marangoni number in eqn (23), it does not give realistic values for evaporation-driven cooling. A better approximation would be:where Hv is the latent heat of vaporization, Cp is the specific heat capacity at constant pressure , D is the diffusion coefficient of the vapor in air, \u03c1 is the liquid density, \u0394c is the difference between the saturated vapor concentration at the interface and in the far field  and DT is the thermal diffusivity of the liquid phase.In the published article, in Section 3.1 \u201cThermal Marangoni flow\u201d, there is a typo in the estimation of \u0394The results and conclusions presented in the published article are unaffected.\u2020 The authors would like to thank Jafar Farhadi for pointing out the typo.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Journal of Healthcare Engineering has retracted the article titled \u201cMiR-139-5p Inhibits the Development of Gastric Cancer through Targeting TPD52\u201d [Following an investigation conducted by the Hindawi Research Integrity team , signifi"}
{"text": "In the original publication , there wThe corrected The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "This minor editorial error did not affect the results or conclusions of the manuscript.The authors apologize for the error."}
{"text": "The correct affiliation details for Mariana Pinto Da Costa are as follows: Mariana Pinto Da Costa, MD, MSc, PhD, Consultant Psychiatrist at South London and Maudsley NHS Foundation Trust and Senior Lecturer at the Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UKThe correct wording in the declaration of interests should be \u201cMPC is a member of the Editorial Board of The British Journal of Psychiatry and of BJPsych Advances\u201d and \u201cHE is a member of the Editorial Board of the British Journal of Psychiatry International\u201d.The authors would like to make two corrections to the above paper.The authors apologise for these errors."}
{"text": "P\u00a0<\u00a0.01, compared with sham (NM) group, &&P\u00a0<\u00a0.01, compared with sham (DM) group, and #P\u00a0<\u00a0.05, ##P\u00a0<\u00a0.01, compared with I/R (DM) groupKnockdown of lncRNA AK139328 inhibited cardiomyocyte apoptosis and autophagy of DM. A and B, Knockdown of lncRNA AK139328 inhibited cardiomyocyte apoptosis in DM. Cardiomyocyte apoptosis in MI/R (DM) group was significantly higher than that in MI/R (NM) group. D, MIRI promoted the expression of Atg7, Atg5 and LC3\u2010II/LC3\u2010I and inhibited the expression of p62, whereas knockdown of lncRNA AK139328 recovered protein expression level. **In the published article by Yu et al., an error was found in Figure 4A\u2010B. Upon clarification from the authors and investigation of the images in the paper, it has been decided to proceed with a corrigendum. The authors confirm all results and conclusions of this article remain unchanged. The corrected figure is shown below:"}
{"text": "Computational Intelligence and Neuroscience has retracted the article titled \u201cEffect of Big Data Analysis-Based Remote Management Combined with Yangyin Runfei Decoction on Coagulation Function, Pulmonary Function, and Quality of Life of Pulmonary Tuberculosis Patients\u201d [atients\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifiThe authors disagree to the retraction."}
{"text": "Retraction Note: J Exp Clin Cancer Res 40, 287 (2021)https://10.1186/s13046-021-02081-8The Editor-in Chief has retracted this article. Concerns were raised about overlap between the Merge/KYSE180 panel in Fig. 5B and the Merge/KYSE30 panel in Fig. 3C ["}
{"text": "The authors wish to add the following information to their Research Paper:In the original published version of this article, one of the affiliations for Prof. G. Santulli was incomplete; the correct affiliation is reported below: Department of Molecular Pharmacology, Wilf Family Cardiovascular Research Institute, Einstein Institute for Aging Research, Institute for Neuroimmunology and Inflammation, Albert Einstein College of Medicine, New York, NY, USA. Moreover, a declaration concerning the competing interest of one of the authors was not included. This issue has now been rectified; the corrected Declaration of Competing Interest can be found below.Prof. B. Trimarco reports personal fees for speaker bureau, outside the content of the current manuscript, from Malesci, Damor, MSD, and Fidia.The authors would like to apologise for any inconvenience caused."}
{"text": "The last two authors, Suresh Mahalingam and Ali Zaid, should have been noted as joint senior authors. The publisher apologizes for the error."}
{"text": "In , the aut1Nanfang Hospital, Southern Medical University, Guangzhou, China.The authors apologize for the error and any inconvenience it may have caused."}
{"text": "The authors wish to make minor corrections to On page 6, the Y axis of On page 7, the color coding was missing in The corrections do not affect the main scientific results and the final conclusions of this manuscript. The authors would like to apologize for any inconvenience caused. The original article has been updated."}
{"text": "This special issue of Software Tools for Technology Transfer comprises extended versions of selected papers from the 26th edition of the International Conference on Tools and Algorithms for the Construction and Analysis of Systems (TACAS 2020). The focus of this conference series is tools and algorithms for the rigorous analysis of software and hardware systems, and the papers in this special cover the spectrum of current work in this field. The International Conference on Tools and Algorithms for the Construction and Analysis of Systems (TACAS) is a forum for researchers and practitioners working with formal tools and techniques for building and analyzing computerized systems. It aims to bridge the gaps between different communities with this common interest and to support them in their quest to improve the utility, reliability, flexibility, and efficiency of tools and algorithms for building systems.TACAS 2020\u00a0, 2 was tTACAS 2020\u00a0, 2 receiIn paper\u00a0, Hadar FIn paper\u00a0, FlorianIn paper\u00a0, BenedikIn paper\u00a0, Thomas In paper\u00a0, Ruben HIn paper\u00a0, Hans-DiIn paper\u00a0, Thom BaIn paper\u00a0, Carlos In paper\u00a0, Suprati"}
{"text": "Epidemiology of Herpes Zoster in the pre-vaccination era: establishing the baseline for vaccination programme\u2019s impact in Spain\u2019 by Risco Risco et al., published on 23 February 2023, the name of Noem\u00ed Lopez-Perea was erroneously written as Noem\u00ed Lopez-Parea. This error was corrected on 7 Mar 2023 upon the request of the authors.In the article \u2018"}
{"text": "Expert and stakeholder consultation workshop on Research on Green ICT 2020-2030. https://digital-strategy.ec.europa.eu/en/library/expert-and-stakeholder-consultation-workshop-research-green-ict-2020-2030. The original reference [90] should instead be [95] and all subsequent references renumbered accordingly.In the originally published version of this article, the authors inadvertently cited an incorrect source for the following statement: \u201c\u2026and a study commissioned by the EC anticipates that \u2018the energy consumption of data centers and telecommunication networks\u00a0will grow with an alarming rate of 35% and 150% respectively over 9 years\u2019 (from 2018).These errors have now been corrected online, and the authors apologize for any confusion they may have caused."}
{"text": "RSC Advances article due to concerns with the reliability of the data.The Royal Society of Chemistry hereby wholly retracts this The first three bands in the \u2018ZO-1\u2019 western blot panel in Fig. 4B are duplicated as the last three bands in the \u2018MyD88\u2019 panel in Fig. 5B. The \u03b2-actin control panel in Fig. 4B is duplicated in Fig. 5B. In addition, in the \u2018Materials and methods\u2019 section, the authors state that GAPDH was used as the reference gene, which does not match with the information presented in Fig. 4B and 5B where \u03b2-actin is used as the control.1 There is also considerable text overlap in the \u2018Results\u2019 and \u2018Materials and methods\u2019 sections with ref. Furthermore, the western blot panels, \u2018ZO-1\u2019  and \u2018MyD88\u2019  were previously published in another paper with no authors in common.Given the significance of the concerns about the validity of the data, and the lack of raw data, the findings presented in this article are not reliable.The authors stated that a third-party testing company conducted the western blot analysis, and the authors directly used the results sent to them by the company in the paper. In previous correspondence, all the authors agreed to voluntarily request the retraction of this manuscript in order to avoid misleading readers.RSC AdvancesSigned: Laura Fisher, Executive Editor, Date: 11th January 2023"}
{"text": "Shawar YR, Mikton CR, Beaulieu M, Yon Y, Campo-Tena L. Clinical resource allocation for the mitigation of elder abuse. Authors\u2019 reply. Lancet Healthy Longev 3: e6502022; \u2014This Correspondence should have been published under a CC BY 3.0 IGO license. This correction has been made as of Nov 7, 2022."}
{"text": "We apologize that, during the image assembly, the fluorescence image acquired at 24 h post-injection was mistakenly chosen as the fluorescence image acquired before injection of 5HFeC NPs. The correct version of the Figure 4A is shown below. We confirm that this correction does not affect any original results and conclusions of the paper. The authors apologize for any inconvenience that the errors may have caused.The authors apologize that the original version of our paper unfortunately contained an incorrect representative image in Figure 4A, where the fluorescence image of an ApoE"}
{"text": "Sci., 2020, 11, 5323\u20135327, https://doi.org/10.1039/D0SC01146K.Correction for \u2018Biofunctional Janus particles promote phagocytosis of tumor cells by macrophages\u2019 by Ya-Ru Zhang  The authors regret an error in The panels for 2 h SPA3 and 2 h Tf + aSIRP\u03b1 + SPA3 contain overlap, as the wrong data was initially used for 2 h SPA3. An independent expert has viewed the new data and has concluded that it is consistent with the discussions and conclusions presented.The correct The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "This abstract has been withdrawn."}
{"text": "Diagnostics 2022, 12, 2345 and add some points for consideration [We wish to congratulate the authors for the successful publication of the article titled \u2018Assessment of Acute Lesions of the Biceps Pulley in Patients with Traumatic Shoulder Dislocation Using MR Imaging\u2019. The authors have mentioned the incidence of biceps pulley lesions as lesions of sGHL alone , lesions of CHL alone , or a combination of both sGHL and CHL. The classification system used is mentioned as the one given by Habermeyer . However, the classification system described by Habermeyer does not mention lesions of CHL [To mitigate this problem, we propose using the simpler and more recent classification system of biceps pulley lesions given by Martetschl\u00e4ger et al. . This cl"}
{"text": "Retraction Note: Cell & Bioscience (2021) 11:169 https://doi.org/10.1186/s13578-021-00675-5The Editors have retracted this article at the request of the authors because several irregularities have been identified in the figures. Specifically:The NC and SiSNHG1#1 panels at 0\u00a0h for MDA-MB-468 cells in Fig.\u00a02e contain overlapping data.The SiSNHG1/MDA-MB-468 panel in Fig.\u00a05l is a duplicate of the SiSNHG1#2/MDA-MB-468 panel in Fig.\u00a02f. There also appears to be an overlap between the panels for NC/MDA-MB-468 between these two figures.The panel for miR-18b-3p mimics in MDA-MB-231 cells in Fig.\u00a04l contains overlap with the SiSNHG1#1 panel for MDA-MB-231 cells in Fig.\u00a02f.Additionally, concerns have been raised regarding ethics approval for the human part of the study, as well as mouse tumour ulceration in Fig.\u00a02k. In view of the number of errors, the article is being retracted.All authors agree to this retraction."}
{"text": "ERRATUM TO: USE OF A MAIT ACTIVATING LIGAND, 5-OP-RU, AS A MUCOSAL ADJUVANT IN A MURINE MODEL OF VIBRIO CHOLERAE O1 VACCINATIONDOI: 10.20411/pai.v7i1.525Reason: The authors sincerely regret the inadvertent omission of Jackson G. Cacioppo as coauthor of this work. He has no additional conflicts of interest.Corrected version: Owen Jensen1,2, Shubhanshi Trivedi1, Jackson G. Cacioppo3, Kelin Li3, Jeffrey Aub\u00e93, J. Scott Hale2, Edward T. Ryan4,5,6, Daniel T. Leung1,2*"}
{"text": "In the original publication, there was a mistake in The investigation by Holbert et al. aimed to examine the effectiveness of a hydrogel burn dressing as an analgesic adjunct to burn first aid in acute paediatric burn patients. No significant between-group differences in pain scores were found between paediatric burn patients who received hydrogel dressings and those who received standard care (2). A clear benefit of hydrogel dressings as an analgesic adjunct to burn first aid was not identified in the investigation (2). The corrected The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "Biol. Open (2016) 5, 62-71 (doi:10.1242/bio.015776).There was an error published in In Fig.\u00a04, the Autumn-control image in panel B was erroneously a duplication of the Autumn-HU image in panel D.The corrected figure is shown below.The authors apologise to readers for this error, which does not impact the results or conclusions of this paper."}
{"text": "Computational and Mathematical Methods in Medicine has retracted the article titled \u201cEffect of Hierarchical Nursing Management in Patients with Hypertension Complicated with Cardiovascular and Cerebrovascular Risk Factors\u201d [Factors\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifi"}
{"text": "Sci., 2022, 13, 7289\u20137294, https://doi.org/10.1039/D2SC00385F.Correction for \u2018The oxygen-resistant [FeFe]-hydrogenase CbA5H harbors an unknown radical signal\u2019 by Melanie Heghmanns  The authors realized that incorrect references were cited following the sentence \u201cIn conjunction with the signal's significant width, the frequency dependence clearly indicates spin\u2013spin interaction between the F-clusters.\u201d The correct references are shown below as ref. Additionally ref. 36 and 37 were reversed in the reference list. The correct ref. 36 is shown below as ref. The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Computational and Mathematical Methods in Medicine has retracted the article titled \u201cIntervention Value of Path-Type Health Education on Cognition and Renal Function of Patients with Diabetic Nephropathy\u201d [ropathy\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifiThe author does not agree to the retraction."}
{"text": "Bioscience Reports at the request of the Editor-in-Chief and the Editorial Board following receipt of a notification from a reader, alerting the Editorial Board to concerns regarding the western blots and flow-cytometry plots of this manuscript. The western blots have concerning features such as the shapes of the bands and absence of any detectable background, and the flow-cytometry plots of Figure 6E share strong similarities with those found in other papers by unrelated authors, including in Figures 2E and 4F of Li et al. 2019 (https://doi.org/10.1080/15384101.2019.1674071). The authors have been contacted with regards to these concerns and subsequently the retraction, but they have not responded to the Journal's queries or the concerns raised. Given the extent of the issues raised, the Editorial Board stand by the decision to retract the article.This article is being retracted from"}
{"text": "H while the panel corresponding to GCTR was copied twice.In the original publication, there was a mistake in Figure 6 as published . Upon thThe authors do apologize for this mistake. The revised version corroborates the conclusions stated in the first version of the article; the wound size was reduced considerably over the 14 days of the postoperative period, compared to the uncoated injuries. The corrected Affiliation CorrectionClassius Ferreira da Silva and Elena Sanchez-Lopez. The original affiliations 4,7,8 should be updated as follows.In the published publication, there was an error regarding the affiliations for Affiliation 4: \u201cDepartment of Exact Sciences and Earth, Federal University of S\u00e3o Paulo (UNIFESP), Rua Prof. Artur Riedel, 275, Diadema CEP 09972-270, Brazil\u201d updated to \u201cDepartment of Chemical Engineering, Federal University of S\u00e3o Paulo (UNIFESP), Rua Prof. Artur Riedel, 275, Diadema 09972-270, Brazil\u201d.Affiliations 7 and 8: \u201c7 Department of Pharmacy, Pharmaceutical Technology and Physical Chemistry, Faculty of Pharmacy and Food Sciences and Institute of Nanoscience and nanotechnology (IN2UB), University of Barcelona, Av. Joan XXIII 27-31, 08028 Barcelona, Spain\u201d, \u201c8 CIBERNED Centros de Biomedicina en Red de Enfermedades Neurodegenerativas, Facultat de Farm\u00e0cia, Universitat de Barcelona, 08028 Barcelona, Spain\u201d should be update to \u201c7 Department of Pharmacy, Pharmaceutical Technology and Physical Chemistry, Faculty of Pharmacy and Food Sciences, Av. Joan XXIII 27-31, 08028 Barcelona, Spain\u201d, \u201c8 Institute of Nanoscience and Nanotechnology (IN2UB), University of Barcelona, Av. Joan XXIII 27-31, 08028 Barcelona, Spain\u201d, \u201c9 Biomedical Research Networking Centre in Neurodegenerative Diseases (CIBERNED), 28031 Madrid, Spain\u201d.Author Name CorrectionThe author\u2019s name \u201cLucas Rannier Andrade\u201d should be changed to \u201cLucas Rannier M. de Andrade\u201d.The authors apologize for any inconvenience caused and confirm that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "The authors wish to make the following correction to this paper .T appeared incorrectly in Section 5.1. Description of Actinotalea subterranea sp. nov.\u2014in the published version of the paper. The correct version of the KCTC number of the type strain HO-Ch2T is as follows:The authors note that the KCTC number of the type strain HO-Ch2T (= VKM Ac-2850T = KCTC 49656T).HO-Ch2The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. The original publication has also been updated."}
{"text": "The Publisher retracts the cited article.Following publication, the publisher uncovered evidence that false identities were used in the peer-review process. The assignment of a fake reviewer was confirmed by an investigation, conducted in accordance with Frontiers\u2019 policies and the Committee on Publication Ethics (COPE) guidelines.The investigation also uncovered concerns about the presentation and validity of the data in the article that normally would have led to a rejection. When contacted, the authors failed to provide a data set that adequately supports the reported conclusions.The authors have not responded to correspondence regarding this retraction.This retraction was approved by the Chief Editors of Frontiers in Physiology and the Chief Executive Editor of Frontiers."}
{"text": "There is a typo in one of the headings in Figure 3 on p. 9. The correct last heading is not \u2018Hazard Ratio\u2019 but \u2018Odds Ratio\u2019. The authors apologize for the mistake."}
{"text": "DOI: 10.1039/C6RA13142E.Retraction of \u2018One-pot synthesis of Hantzsch dihydropyridines using a highly efficient and stable PdRuNi@GO catalyst\u2019 by Tuna Demirci  RSC Advances article due to concerns with the reliability of the data in the published article.The Royal Society of Chemistry hereby wholly retracts this The particle size histogram of PdRuNi@GO NPs in Fig. 2c has the same relative bar heights as particle size histograms in at least six other papers by the same authors, all representing different nanoparticles or synthetic methods. The authors provided replacement data for consideration. However, an expert reviewed the authors\u2019 response and concluded that it did not satisfactorily address the concerns, and that the replacement figure did not fully support the conclusions.Scientific Reports in Fig. 2d to represent PdNi@rGO.1 The 3D Pd3d XPS spectra for PdRuNi@GO nanoparticles in Fig. 3a was later published by the authors in Nano-Structures & Nano-Objects in Fig. 2a to represent PdRu@GO nanocomposites.2The 2D Pd3d XPS spectra for PdRuNi@GO nanoparticles in Fig. 3a was later published by the authors in Nano-Structures & Nano-Objects in Fig. 2b to represent PdRu@GO nanocomposites,2 in the Journal of Molecular Liquids in Fig. 3b to represent Ru(0)/graphite NPs,3 in Nanocarbon and its Composites in Fig. 3b to represent Ru/PVP@C4 and previously by the authors in Chemistry Select in Fig. 3b to represent RuPd@GO NPs.5The 3D Ru3p XPS spectra for PdRuNi@GO nanoparticles in Fig. 3b was later published by the authors in Biosensors & Bioelectronics in Fig. 2b to represent Ni@f-MWCNT.6 The authors claim that the XPS spectra in Fig. 3 were included in error and provided replacement data for consideration. However, an expert reviewed the author\u2019s response and concluded that it did not satisfactorily address the concerns, and that the replacement figure did not fully support the conclusions.The 3D Ni2p XPS spectra for PdRuNi@GO nanoparticles in Fig. 3b was later published by the authors in Given the significance of the concerns about the validity of the data, the findings presented in this paper are no longer reliable.Sinan Eri\u015f, Tuna Demirci, Mustafa Arslan, Benan Kilbas and Fatih Sen oppose this retraction. Bet\u00fcl \u00c7elik and Yunus Y\u0131ld\u0131z were contacted but did not respond.RSC AdvancesSigned: Laura Fisher, Executive Editor, rd September 2021Date: 23"}
{"text": "Scientific Data 10.1038/s41597-022-01591-0, published online 13 August 2022Correction to: The order of the tables on the in original version was incorrect, with tables published in the wrong positions and associated with the wrong captions. This has now been corrected as followsThe original Table 1 has been moved to the Table 4 captionThe original Table 2 has been moved to the Table 5 captionThe original Table 3 has been moved to the Table 6 captionThe original Table 4 has been moved to the Table 7 captionThe original Table 5 has been moved to the Table 1 captionThe original Table 6 has been moved to the Table 2 captionThe original Table 7 has been moved to the Table 3 captionThe Table 3 caption was also truncated, and has now been replaced with the full version \u201cCross-tabulation of land use (lu) and year built (by) completeness; \u201cn\u201d indicates missingness, e.g., nby = \u201cno built year\u201d.These errors have been corrected in the HTML and PDF versions of the paper."}
{"text": "Journal of Healthcare Engineering has retracted the article titled \u201cDosimetric Comparison between Volumetric Modulated Arc Therapy (VMAT) and Intensity-Modulated Radiotherapy (IMRT) for Dental Structures of Head and Neck Cancer Patients\u201d [atients\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifiThe authors agree to the retraction."}
{"text": "Nature Communications 10.1038/s41467-022-31388-z, published online 24 June 2022Correction to: The original version of this Article contained an error in the <Endothelial cell heterogeneity> section of the Results, which incorrectly read \u2018<Our results showed that EndMT cells can be clearly identified in adipose tissues with co-expression of PECAM1 and ACTA2 , as well as VWF and TAGLN, in a small fraction of ECs .>.\u2019 The correct version states \u2018<Our results showed that EndMT cells can be clearly identified in adipose tissues with co-expression of VWF and TAGLN , as well as PECAM1 and ACTA2 , in a small fraction of ECs.>\u2019.n = 3). j. Representative Immunofluorescence staining images of VWF and TAGLN in adipose tissues. Arrow (red) indicates ECs expressing both VWF and TAGLN. Arrow (green) indicates ECs only expressing VWF (n = 3). k. IHC of FABP4 in ECs and adipose tissues. Arrows (red) indicate ECs. Arrows (green) indicate adipocytes. Control was stained with an antibody against a gene not expressed in adipose tissues (n = 3).>.\u2019 The correct version states \u2018<i. Representative Immunofluorescence staining images of VWF and TAGLN in adipose tissues. Arrow (red) indicates ECs expressing both VWF and TAGLN. Arrow (green) indicates ECs only expressing VWF (n = 3). j. Representative Immunofluorescence staining images of PECAM1 and ACTA2 in adipose tissue. Arrow (red) indicates ECs expressing both PECAM1 and ACTA2. Arrow (green) indicates ECs only expressing PECAM1 (n = 3). k. IHC of FABP4 in ECs and adipose tissues. Arrows (green) indicate ECs. Arrows (red) indicate adipocytes. Control was stained with an antibody against a gene not expressed in adipose tissues (n = 3).>\u2019.The original version of this Article contained an error in the legend to Figure 3, which incorrectly read \u2018<i. Representative Immunofluorescence staining images of PECAM1 and ACTA2 in adipose tissue. Arrow (red) indicates ECs expressing both PECAM1 and ACTA2. Arrow (green) indicates ECs only expressing PECAM1  was less than 30%.>.\u2019 The correct version states \u2018<Cells were only retained if the number of detected genes were greater than 200 and less than 5000 and the percentage of detected mitochondrial transcripts from MT genes  was less than 30%. The Pig ND1 gene was not included in MT-based filtering due to high sequence variant in pigs.>\u2019.This has been corrected in both the PDF and HTML versions of the Article."}
{"text": "Retraction Note: Mol Cancer 18, 25 (2019)https://doi.org/10.1186/s12943-019-0958-6The Editor-in-Chief has retracted this article at the authors' request. After publications, concerns were raised regarding image overlap in Figs. 4 and 5, which the authors addressed via a Correction . HoweverFurthermore, BGC823, MGC803 and SGC7901 cells used in this study are known to be contaminated  with HeLa cells, making them an unsuitable model for gastric cancer [The authors have provided the raw data to address the image concerns, but have requested to retract the article due to the cell line contamination.Shuli Zhao, Weiwei Tang and Hongyong Cao agree to this retraction. Chen Lu and Kai Fu have not responded to any correspondence from the editor or publisher about this retraction. The Publisher has not been able to obtain current email addresses for Dawei Rong and Betty Zhang."}
{"text": "Jo et al., RSC Adv., 2018, 8, 5158\u20135165.Correction for \u2018Role of annealing temperature on the sol\u2013gel synthesis of VO The authors regret that one of the funders was omitted from the acknowledgements in the original article. The full acknowledgements should read: \u201cThis work was supported by the Samsung Research Funding Center of Samsung Electronics under Project Number SRFC-MA1402-10 and the National Research Foundation of Korea (NRF) under Grant NRF2013S1A2A2035468.\u201dThe Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "The following information is missing from the Acknowledgments: The authors would like to extend their sincere appreciation to the Researchers Supporting Project Number (RSP-2021/134), King Saud University, Riyadh, Saudi Arabia."}
{"text": "Correction to: Hernia (2022) 26:1695\u20131705 10.1007/s10029-022-02664-0The funding note which currently reads:\u201cThis work was supported by federal grants: The Swedish Research Council 2017-00824\u201dBut it should read as The Swedish Research Council 2021-00972.The authors apologies for this mistake.The original article has been corrected."}
{"text": "Ajuga bracteosa and to the writing the original manuscript. The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. The original publication has also been updated.The authors of this paper  have agr"}
{"text": "Large\u2010scale production, purification, and function of a tumor multi\u2010epitope vaccine: Peptibody with bFGF/VEGFALigang Zhang, Chengcheng Jiang, Xi Chen, Jiangtao Gu, Qifang Song, Hui Zhong, Sheng Xiong, Qingfeng Dong, Jin\u2010Chen Yu, Ning DengEng. Life Sci. 2020, 20, 422\u2013436https://doi.org/10.1002/elsc.202000020First published: 29 July 2020For the above\u2010mentioned article, concerns about image integrity were raised by a third party. The authors apologize for their carelessness and make corrections to their published paper. Figures\u00a0FigureFigureBased on the repeated fermentation, the text in the results \u201c3.2 Optimization of Peptibody production from flask to 10\u2010L bioreactor\u201d, last paragraph, needs to be adjusted and now reads \u201cThe time\u2010course profiles of cell growth and analysis of Peptibody expression were presented in Figure\u00a0FigureFigure4/well) suspended in serum\u2010free\u2026.\u201d. The revised figure is given below."}
{"text": "After having re-examined their original data, the authors conceded that the figure had been assembled incorrectly . Furthermore, the first author on the paper (Wei Dai) also acknowledged that several of the named authors had not given their prior consent to be included as such as authors on the paper, and therefore a request was made that the paper be retracted from the publication.Oncology Reports has accepted the authors' request that the paper be retracted from the journal. The Editor apologizes to the readership for any inconvenience caused.In view of these admissions, the Editor of"}
{"text": "The authors would like to correct the keyword \u2018bare RNLF\u2019 to \u2018RNFL schisis\u2019 in their prior publication . The worThe authors would like to apologize for any inconvenience caused to the readers by these changes."}
{"text": "In our paper, the authors noted one error in Fig."}
{"text": "Journal of Healthcare Engineering has retracted the article titled \u201cA Controlled Study of Continuous Lumbar Drainage of Fluid and Lumbar Puncture Drainage for Aneurysmal SAH after Intracranial Aneurysm Clipping\u201d [lipping\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifi"}
{"text": "In the original publication , there wThe authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "There is an error in"}
{"text": "Correction: J Exp Clin Cancer Res 41, 112 (2022)https://doi.org/10.1186/s13046-022-02320-6Following publication of the original article , author Incorrect Funding:This research was funded by Fondazione AIRC under 5 per Mille 2018 \u2013 ID 21052 program - PI: Comoglio PM, GL: Vigna E; by FPRC 5xmille 2014 Ministero Salute to PMC, and by Ministero Salute, Ricerca Corrente 2018\u20132020. The studies performed by Accelera Srl. were sponsored by Metis Precision Medicine B-Corp.Correct Funding:by Italian Association for Cancer Research (AIRC), IG 20210 to S. Giordano, and IG 21770 to S. Corso; by FPRC 5xmille 2014 Ministero Salute to PMC, and by Ministero Salute, Ricerca Corrente 2018-2020. The studies performed by Accelera Srl. were sponsored by Metis Precision Medicine B-Corp.This research was funded by Fondazione AIRC under 5 per Mille 2018 - ID 21052 program - PI: Comoglio PM, GL: Vigna E; The correction does not have any effect on the final conclusions of the paper. The original article has been corrected."}
{"text": "Vol. 216, No. 5 | 10.1084/jem.20181473 | April 2, 2019Tshr siRNA sequence listed in the TSHR siRNA interference section of the Materials and methods was incorrect. The correct sequence is sense, 5\u2032-ACCAGAAGCUUAACCUAUA-3\u2032; anti-sense, 5\u2032-GUACAACAAUGGAUUUACU-3\u2032.The authors regret that in their original paper, the The error appears in print and in PDFs downloaded before December 20, 2021."}
{"text": "RSC Advances article due to concerns with the reliability of the data.The Royal Society of Chemistry hereby wholly retracts this Part of the image in Fig. 1g  panel) is a scaled, rotated and inverted version of the image in Fig. 3d .The authors also informed the editor that incorrect H&E staining images, labelled with bpV(pic)/PLGA-ASC, were used in Fig. 4c.Given the significance of the concerns about the validity of the data in the article, the findings presented in this paper are not reliable.The authors do not agree with the decision to retract the article.RSC AdvancesSigned: Laura Fisher, Executive Editor, Date: 22nd December 2022"}
{"text": "Background: Medical University of South Carolina Health began vaccinating care team members December 15, 2020, with the Pfizer-BioNTech SARS-CoV-2 mRNA vaccine. We report surveillance data for cases diagnosed following vaccination. Methods: Care team members (CTMs) diagnosed with COVID-19 following SARS-CoV-2 vaccination were self-identified during online electronic contact-tracing surveys. Demographic data, symptoms, and dates of symptoms were recorded. CTMs testing positive at MUSC were linked to viral burden data from nasopharyngeal swabs tested on Abbott PCR platforms. Results: As of January 31, 2021, 111 CTMs tested positive for SARS-CoV-2 following vaccination: 99 and 12 after 1 and 2 doses, respectively, at medians of 10 days  and 5 days , respectively, from vaccination to testing. Of 2 cases that tested positive >14 days from dose 2, CTMs had symptom onset at 4 and 12 days from dose 2. Among CTMs reporting symptoms, 104 did so after a median of 7 days  from vaccination to symptom onset, with 8 reporting symptoms before vaccination, 9 on the day of vaccination, and 3 CTMs at 1 day after vaccination, 6 CTMs at 2 days after vaccination, and 11 CTMs at 3 days after vaccination. Overall, 86 (78%) of 111 were female and 95 (86%) of 111 were white. The median age was 44 years . Clinical job roles were most frequently nurses , physicians or physician extenders , and CTMs with no patient contact . Assessment by the contact-tracing team assigned sources as household clusters , local transmission , occupational acquisition from coworkers , travel related , and unknown . Only 32 (32%) CTMs were compliant with physical distancing. Among 104 CTMs reporting symptoms, cough (75%), headache (71%), rhinorrhea (63%), myalgia (60%), sore throat (48%), anosmia (44%), and subjective fever (40%) were the most commonly reported symptoms. Among 54 symptomatic CTMs with available viral-load data, the median and mean cycle numbers (Cn) were 19.98 and 21.91, respectively, for samples tested a median 3 days from symptom onset. Asymptomatic and symptomatic CTMs had a median Cn of 30.1 vs 20.9, respectively (p <0.001) and overall 50% of vaccinated CTMs had Cn >20, with no significant effect seen by vaccine dose (Figure Conclusions: Most COVID-19 cases following vaccination occurred in CTMs with infection incubating prior to vaccination. No significant attenuation of viral load is apparent among vaccinated CTMs with COVID-19, but asymptomatic CTMs diagnosed with COVID-19 following vaccination appear to have resolved infections. Our data reinforce the need to adhere to public health measures by people who have been vaccinated.Funding: NoDisclosures: None"}
{"text": "Estimated number of deaths directly averted in people 60 years and older as a result of COVID-19 vaccination in the WHO European Region, December 2020 to November 2021\u201d by Mesl\u00e9 et al. was missing one set of brackets. This was corrected on 23 May 2022 at the request of the authors. As originally published, equation 2 in the article \u201c"}
{"text": "Cell Death and Disease 10.1038/s41419-017-0077-5, published online 14 December 2017Retraction to: The Editors-in-Chief have retracted this article because of significant concerns regarding Figure 2C, Supplementary Figures 5 and 6 presented in this work, which question the integrity of the data. Therefore, the Editors-in-Chief, no longer have confidence in the integrity of the data in this article. Authors Wen-Fei Wei, Xiaojing Chen, Lina He, Xiangguang Wu and Wei Wang have not explicitly stated whether they agree to this retraction notice. The editors were not able to obtain a current email address for Mei Zhong, Yan-Hong Yu and Li Liang. Chen-Fei Zhou, Lan-Fang Wu, and Rui-Ming Yan have not responded to any correspondence from the editor/publisher about this retraction."}
{"text": "In the original publication , there wThe authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "The authors wish to make the following corrections to this paper :In the original published article, the Institutional Review Board Statement was not included. The Institutional Review Board Statement is added below.Institutional Review Board Statement: Ethics approval was obtained from each of the two institutions: The Internal Ethics Review Committee of the Koret School of Veterinary Medicine Veterinary Teaching Hospital, Israel, certificate number KSVM-VTH/07_2015 and Veterinary Research Ethics Committee, University of Liverpool, UK, certificate number VREC237.The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. The original publication has also been updated."}
{"text": "Retraction Note To: Stem Cell Research & Therapy (2021) 12:2 10.1186/s13287-020-02030-wThe Editors-in-Chief have retracted this paper after the authors reported discrepancies in the data. Specifically, the authors have stated that the data presented in the paper is incomplete; that the analysis did not use appropriate statistical tests, and that the combination of these factors resulted in inaccurate conclusions that are not supported by the data. Further investigation from the publisher has found that Figure\u00a04B displays the same image as Figure\u00a01D in Gou et al. ["}
{"text": "The authors regret that these errors were included in the paper, and also apologize to the readership for any inconvenience caused.The authors have consulted their original data, and realized that the errors in the presentation of these figures arose inadvertently as a consequence of selecting the wrong images for the 24 h \u2018Blank\u2019 experiement in"}
{"text": "T. N. Nha et al., RSC Adv., 2021, 11, 30054\u201330068. DOI: 10.1039/D1RA03216JCorrection for \u2018Sensitive MnFe The authors regret that an incorrect grant number was shown in the acknowledgements section of the published article. The corrected section should read:This work was supported by the Vietnam Academy of Science and Technology (VAST) by Program of Development in the field of Physics by 2020 under grant number KHCBVL.02/20-21, and partly by AOARD Award No. FA2386-17-1-4042.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Vessel Plus [In the original publication , a substsel Plus  without The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "Dokorou et al.1 The crystal structure reported by Dokorou is incorrect as they mistakenly doubled the unit cell, leading us to believe we were reporting a new form.The new form, 2 highlights our error in reporting form II as new.The recently published Comment articleThe Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "A random survey of the prevalence of falsified and substandard antibiotics in the Lao PDR. J Antimicrob Chemother 2019; 74: 2417\u201325. https://doi.org/10.1093/jac/dkz164.Tabernero P, Swamidoss I, Mayxay M Journal of Antimicrobial Chemotherapy (JAC) has been retracted and republished1 to correct errors identified by the authors after publication of the original item.This article published in the Following publication of the original manuscript, the authors became aware that the reference ranges used to classify samples as meeting the pharmacopoeial specifications for assay [percentage of active pharmaceutical ingredient (%API) of the label claim] were incorrect.The authors re-analysed the relevant data with the correct pharmacopoeial specifications for assay for the collected medicines and compared the results with those in the originally published manuscript.JAC\u2019s Editorial Board, the Editor-in-Chief and the original peer reviewer. Given the number and nature of the corrections required, the full corrected item has been republished in JAC.1The corrected version of the manuscript was reviewed by a member of The authors apologize for their error, and the Journal apologizes for any confusion caused."}
{"text": "Relative to pure NH2-UiO-66, Pt@NH2-UiO-66, and NH2-UiO-66/CdS samples, the Pt@NH2-UiO-66/CdS composite exhibits much higher hydrogen yields with an apparent quantum efficiency of 40.3% at 400\u2009nm irradiation and stability over the most MOF-based photocatalysts. Transient absorption measurements reveal spatial charge-separation dynamics in the composites. The catalyst\u2019s high activity and durability are attributed to charge separation following an efficient photogenerated hole-transfer band-trap pathway. This work holds promise for enhanced MOF-based photocatalysis using efficient hole-transfer routes.Efficient electron-hole separation and carrier utilization are key factors in photocatalytic systems. Here, we use a metal-organic framework (NH 2-UiO-66/CdS, resulting in photocatalytic hydrogen evolution with good stability and a quantum efficiency of 40.3% at 400\u2009nm irradiation.Efficient electron-hole separation and carrier utilization are key factors in photosynthetic systems. Here, the authors achieve efficient charge separation following a photogenerated hole-transfer band-trap pathway in the ternary composite Pt@NH Since Fujishima and Honda first reported solar energy conversion for hydrogen evolution using semiconductor-based photocatalysts, we have witnessed the development of artificial photocatalytic systems for enhanced hydrogen evolution reactions (HER)10. The primary drawback in using a pure semiconductor was fast recombination of photoinduced carriers, which seriously limited photocatalytic efficiency12. Meanwhile, co-catalysts, such as Pt nanoparticles (NPs) and RuO2, have been alternatives that provide an active center for redox reductions, reduce overpotentials for HER or oxidation reactions, and promote fast separations of photoinduced electrons and holes16. Thus, complex heterostructures with spatial charge separations via fine control of photoinduced carrier dynamics have been fabricated to improve photocatalytic activity.Photocatalytic hydrogen evolution via water splitting is a promising way to mitigate current energy and environmental issues18, exhibit poor visible-light absorption. The introduction of amino groups into the terephthalic acid ligands of UiO-66 (Zr) broaden light absorption to the visible region, and the presence of amino groups does not affect the structural stability of the UiO-66 host19. Photoinduced electron dynamics in MOFs have been well investigated, but the kinetics of photogenerated holes and their effect on photocatalytic activity remain poorly understood. Cadmium sulfide (CdS) has been the preferred visible-light photocatalyst for HER. However, photoinduced corrosion and fast recombination of photoinduced electron\u2212hole pairs have severely restricted improvements in its catalytic activity. Thus, fine-tuning photoinduced carrier dynamics is necessary to suppress corrosion by accumulated holes27.Metal-organic frameworks (MOFs) are porous crystalline materials with high specific-surface areas, and tunable structures and functionalities. As alternatives to semiconductor photocatalysts that are receiving much interest in a wide range of applications. Unfortunately, MOFs, such as UiO-66 (Zr)2-UiO-66/CdS). Relative to other MOF-based systems , revealed that a unique hole-transfer pathway was responsible for the enhanced and stable HER. The present results could help design spatial, multi-phase, heterostructured photocatalysts with high photocatalytic activity and facile control of photoinduced carrier dynamics.Here, we synthesized a spatial charge structure for the MOF-based photocatalyst  by in-situ encapsulation of Pt nanoparticles (NPs) into MOFs having regular 100-nm octahedral shapes, and by growing CdS on the outer MOF surface, as shown in Supplementary Fig.\u00a02-UiO-66 NCs with regular octahedral structures, which were consistent with scanning electron microscopy images in Supplementary Fig.\u00a02-UiO-66, Pt@NH2-UiO-66/CdS HNCs were formed with a spatial configuration of inner Pt NPs and outer CdS, as shown in Fig.\u00a02-UiO-66/CdS HNCs that shows the CdS NPs attached to the surface of the MOFs. X-ray diffraction patterns in Supplementary Fig.\u00a02-UiO-66/CdS HNCs were composed of NH2-UiO-66 and zinc blend CdS, with Joint Committee on Power Diffraction Standards (JCPDS) no. 10-0454 phases. The Zr/Cd weight ratio was 0.28:14.3, as determined by inductively coupled plasma optical emission spectroscopy (ICP-OES). However, the Pt NPs did not display a diffraction peak due to the low amount of Pt (about 0.023 wt %) determined by ICP-OES , Pt@NH2-UiO-66 (722\u2009m2\u2009g\u22121), Pt@NH2-UiO-66/CdS (612\u2009m2\u2009g\u22121) HNCs, the smaller specific-surface area of Pt@NH2-UiO-66/CdS indicated that the CdS occupies the surface sites of the MOF. In addition, compared with that of NH2-UiO-66 and Pt@NH2-UiO-66, the porous volume of Pt@NH2-UiO-66/CdS was increased due to the effects of CdS NPs. We also further verified the composition and interface characteristics of Pt@NH2-UiO-66/CdS composites by the X-ray photoelectron spectroscopy (XPS) measurements , Pt@NH2-UiO-66 (0.12\u2009mmol\u2009h\u22121\u2009g\u22121), NH2-UiO-66/CdS . The photocatalytic H2 evolution has increased with the increase of the amount of catalyst, then decreased when the dosage of catalyst was 10\u2009mg 32  of Pt@NH2-UiO-66/CdS shown in Fig.\u00a02-UiO-66/CdS had the highest photocatalytic activity and stability, due to the spatial separation of the photoinduced electrons and holes. To reveal the separation and recombination of these charge carriers, we characterized the photoluminescence (PL), transient photocurrent spectra and electrochemical impedance spectroscopy. Pt@NH2-UiO-66/CdS exhibited a very low fluorescence intensity relative to that for NH2-UiO-66, Pt@NH2-UiO-66 and NH2-UiO-66/CdS  and 225\u2009ps (\u03c42), respectively, which may be attributed to electron-trap states in the intermediate band37. For Pt@NH2-UiO-66, similar features were observed in Fig.\u00a02-UiO-66/CdS shown in Fig.\u00a02-UiO-66/CdS , suggesting electron transfers from CdS to NH2-UiO-66. The fast recovery with the 9.3-ps time constant indicated that the electron from NH2-UiO-66 transferred to the Pt phase. The fs TAS suggested that the electron transferred from CdS to NH2-UiO-66, and was then trapped at NH2-UiO-66 before finally transferring to the Pt phase. The hole from NH2-UiO-66 was transferred to CdS. Time-resolved PL spectroscopy was used to investigate the lifetimes of photoinduced carriers in Pt@NH2-UiO-66/CdS33. Figure\u00a02-UiO-66, Pt@NH2-UiO-66, NH2-UiO-66/CdS and Pt@NH2-UiO-66/CdS, respectively  measurements were performed to track photoinduced carrier dynamics to investigate electron and hole transfers in the mechanism of photocatalytic HER. Figure\u00a0\u2022+) with an absorption feature at 600 nm39. Figure\u00a02-UiO-66 upon 355-nm laser excitation in the presence of TPA; the TPA was not excited by the laser  as a hole indicator. It was oxidized by photogenerated holes to form a cation radical  solution of ZrCl4 (18.64\u2009mg) and 5\u2009mL of a DMF solution of 2-amino-1,4-benzenedicarboxylic acid (NH2-BDC) (14.5\u2009mg) were mixed in a beaker. Then, 1.2\u2009mL of acetic acid was added to the solution and transferred to a 50-mL Teflon-lined stainless-steel autoclave at 120\u2009\u00b0C for 24\u2009h. The product was purified via centrifugation and washed with ethanol and hexane. The NH2-UiO-66 was dried overnight at 60\u2009\u00b0C under vacuum.The procedures for synthesizing NH4  and NH2-BDC  was shaken to form a homogeneous solution. Then, a Pt NP solution  and acetic acid (2.74\u2009mL) were added. After sonication for 10\u2009min, the mixed solution was transferred to a Teflon-lined stainless-steel autoclave at 120\u2009\u00b0Cfor 24\u2009h. Finally, the products were collected by centrifugation and dried overnight at 60\u2009\u00b0C under vacuum.The mixture containing ZrCl3COO)2\u00b72H2O was dissolved in 10\u2009mL of ethanol forming a homogeneous solution. Then, 40\u2009mg of Pt@NH2-UiO-66 was added to the solution that was then sonicated for 10\u2009min. The suspension was heated to 80\u2009\u00b0C at 6\u2009\u00b0C min\u22121. At this point, 10\u2009mL of an aqueous solution of thioacetamide (6.9\u2009mg) was slowly injected into the flask with the rate of 0.3\u2009mL\u2009min\u22121. It was kept at 80\u2009\u00b0C for another 30\u2009min. The precipitates were filtered and washed with water and ethanol several times. Finally, the product was dried at 60\u2009\u00b0C under vacuum for 8\u2009h.Typically, 24.3\u2009mg of Cd. Electron-paramagnetic-resonance spectra were acquired with a JEOL FA300 spectrometer with a 9.05-GHz magnetic field modulation at a microwave power of 0.998\u2009mW. 5,5-dimethyl-1-pyrroline N-oxide (DMPO) was used as the spin-trapping reagent. Catalyst (5\u2009mg) was suspended in the mixture of water (500\u2009\u03bcL) and DMPO (50\u2009\u03bcL) for the detection of \u2022OH radicals. After ultrasonication, the detection of \u2022OH in a N2 atmosphere was performed under irradiation with a 300-W Xe lamp with a 420-nm filter for 5\u2009min. Time-resolved fluorescence decay spectra were acquired with an EI FLS-1000 fluorescence spectrometer.TEM characterization was performed with a HT7820  electron microscope at an acceleration voltage of 120\u2009kV. High-resolution TEM, high-angle annular dark-field scanning TEM, and energy-dispersive spectrometry mapping were performed with a TalosF200x  electron microscope at an acceleration voltage of 200\u2009kV. An X-ray diffractometer (RigakuD/MAX-2000) with Cu K\u03b1 radiation (1.5406\u2009\u00c5) at 40\u2009kV and 30\u2009mA was used to record powder X-ray diffraction patterns. The patterns were collected over a 2\u03b8 range of 3\u00b0\u201380\u00b0 at a scanning speed of 5\u00b0 min2 for 30\u2009min to remove dissolved oxygen, followed by 300-W Xe light irradiation with a UV cutoff filter (>420\u2009nm). Gas chromatography  using a thermal conductivity detector was used to measure the HER.For photocatalytic HER, the photocatalyst (5\u2009mg) was dispersed in 25\u2009mL of acetonitrile and 3\u2009mL of deionized water with 3\u2009mL of lactic acid. Then the suspension was stirred in a photocatalytic reactor and purged with NThe apparent quantum yield (AQY) in the above photocatalytic reaction conditions was determined. The excitation light was regulated by a bandpass filter. The intensity of the light was measured with a power meter. The AQY was calculated according to the following equation:Supplementary Information"}
{"text": "RSC Advances article due to concerns with the reliability of the data in the published article.The Royal Society of Chemistry, with the agreement of the authors, hereby wholly retracts this 1The SEM image in Fig. 1C duplicates data published in another publication, but reported as different materials.There are unexpected similarities in the XPS spectra presented for M1\u2013rGO and M5\u2013rGO in Fig. 2A.Repeating fragments can be observed in the baseline of the XRD spectrum for GO presented in Fig. 2B, which indicate that it has been manipulated. In addition, the XRD spectrum for M5\u2013rGO in Fig. 2B duplicates data published in Given the number and significance of the concerns about the validity of the data, the findings presented in this paper are no longer reliable.Signed: Wencai Cheng, Zhongxiu Jin, Congcong Ding and Maolin Wangth March 2020Date: 27RSC AdvancesRetraction endorsed by Laura Fisher, Executive Editor,"}
{"text": "In the article by Yongxin Zhou et\u00a0al., (2021), the authors noted some minor errors in Figure\u00a0These corrections have no impact on the experimental outcome or conclusions."}
{"text": "Journal of Healthcare Engineering has retracted the article titled \u201cStudy on the Mechanism of Platelet-Released Clusterins Inducing Restenosis after Carotid Endarterectomy by Activating TLR3/NF-\u03bab p65 Signaling Pathway\u201d [Pathway\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifiThe authors do not agree to the retraction."}
{"text": "Journal of Healthcare Engineering has retracted the article titled \u201cClinical Characteristics of Patients with Pulmonary Thromboembolism Based on Computer Statistical Analysis\u201d [nalysis\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifiThe authors do not agree to the retraction."}
{"text": "Error in FigureThe authors wish to make the following correction to this paper . Due to The authors would like to apologize for any inconvenience caused to the readers by these changes. The original publication has also been updated."}
{"text": "Retraction Note: BMC Oral Health (2019) 19:290 10.1186/s12903-019-0980-5The Editor has retracted this article. After publication concerns were raised that the data presented are owned by the National Congenital Malformation Registries network of Italy [Emilia-Romagna Registry of Birth Defects (IMER) and Registro Toscano Difetti Congeniti (RTDC)]. The authors have not been able to demonstrate ownership of the data in this article. G. Galluccio and A. Impellizzeri do not agree to this retraction. I. Giannantoni, A. Polimeni and E. Barbato have not responded to correspondence from the Editor about this retraction."}
{"text": "Journal of Healthcare Engineering has retracted the article titled \u201cRobotic-Assisted Laparoscopic Sacrocolpopexy for Pelvic Organ Prolapse: A Single Center Experience in China\u201d [n China\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifiThe authors do not agree to the retraction."}
{"text": "This abstract has been withdrawn"}
{"text": "Sci., 2022, 13, 8752\u20138758, https://doi.org/10.1039/d2sc01561g.Correction for \u2018Highly selective acid-catalyzed olefin isomerization of limonene to terpinolene by kinetic suppression of overreactions in a confined space of porous metal\u2013macrocycle frameworks\u2019 by Wei He  The authors regret that there were errors in The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "The 40-Hz auditory steady-state response (ASSR) has received special attention as an index of gamma oscillations owing to its association with various neuropsychiatric disorders including schizophrenia. When a periodic stimulus is presented, oscillatory responses are often elicited not only at the stimulus frequency, but also at its harmonic frequencies. However, little is known about the effect of 40-Hz subharmonic stimuli on the activity of the 40-Hz ASSR. In the present magnetoencephalography study, we focused on the nature of oscillation harmonics and examined oscillations in a wide frequency range using a time-frequency analysis during the 6.67-, 8-, 10-, 13.3-, 20-, and 40-Hz auditory stimuli in 23 healthy subjects. The results suggested that the 40-Hz ASSR represents activation of a specific circuit tuned to this frequency. Particularly, oscillations elicited by 13.3- and 20-Hz stimuli exhibited significant enhancement at 40 Hz without changing those at the stimulus frequency. In addition, it was found that there was a non-linear response to stimulation in the beta band. We also demonstrated that the inhibition of beta to low-gamma oscillations by the 40-Hz circuit contributed to the violation of the rule that harmonic oscillations gradually decrease at higher frequencies. These findings can advance our understanding of oscillatory abnormalities in patients with schizophrenia in the future. Steady-state responses (SSRs) are evoked oscillatory responses driven by a train of stimuli delivered at a sufficiently high rate. SSRs can be recorded non-invasively using electroencephalography (EEG) and magnetoencephalography (MEG) in different sensory modalities. Auditory steady-state responses (ASSRs) reach maximum amplitude at approximately 40 Hz , which iIn a frequency domain representation, when a periodic stimulus that induces SSR is presented, brain oscillatory responses are elicited not only at the stimulus frequency, but also may occur at its harmonic frequencies, which are integral multiples of the stimulus frequency . For exaWe enrolled 23 healthy volunteers (9 women and 14 men) aged 24\u201362 . The subjects were not using any medications at the time of testing and had no history of mental or neurological illnesses or substance misuse in the previous 2 years. The patients had a hearing threshold of <25 dB at 1,000 Hz, which was assessed using an audiometer .via earpieces , and the sound pressure was controlled with an audiometer .Auditory stimuli were induced using repeats of a brief pure tone. The pure tone was 800 Hz in frequency, and the sound pressure level was 70 dB. Six pure tones were played in durations of 150, 125, 100, 75, 50, and 25 ms . Each tone was repeated until the time threshold of 1,000 ms was reached. Therefore, there were six frequency conditions: 6.67, 8, 10, 13.33, 20, and 40 Hz. The sound stimulus was presented binaurally Magnetic signals were recorded using a 306-channel whole-head MEG system  composed of 102 identical triple sensor elements. Three separate measurements of magnetic fields were obtained from each sensor element\u2019s two orthogonal planar gradiometers, one magnetometer, and multi-superconducting quantum interference device. The MEG signals were recorded using 204 planar-type gradiometers. Signals were captured using a 0.1\u2013300 Hz band-pass filter and were digitized at 1,000 Hz. Epochs with MEG signals of >2.7 pT/cm were excluded from the average.The experiments were conducted in a silent, magnetically protected room. The participants were instructed to sit in a chair and watch a silent movie projected on a screen 1.5 m in front of them and to ignore the auditory stimulation. The six auditory stimuli were randomly presented with an even probability using a stimulus onset asynchrony of 1,500 ms. A total of at least 100 artifact-free epochs were averaged for each stimulus per participant.Signal space projection was used to suppress environmental noise. Artifacts due to eye blinks or the heart were removed using independent component analysis if visually detectable. Then, dipole analyses were performed to estimate an equivalent current dipole for the main component of the ASSR by hemisphere. In the present study, only dipole analysis was used for source estimation. For dipole analyses, the Brain Electrical Source Analysis software package  was used. The MEG waveforms of the 40-Hz condition were averaged across 100 trials and were digitally filtered with a band-pass filter of 37.5\u201342.5 Hz. The equivalent current dipole for the main component of the ASSR was estimated per hemisphere in a time window of 200\u20131,000 ms. The left and right dipoles for the main components of the 40 Hz ASSR were estimated for all 23 subjects. However, in some cases, we could not estimate the dipoles in other conditions. Therefore, as in a previous study , the obtPost hoc paired comparisons were performed using Bonferroni adjusted t-tests when the hemisphere \u00d7 PrePost interaction effects were significant. Post/Pre ratios of amplitude and ITPC at 40 Hz for conditions with significant increases were compared using two-way ANOVA with hemisphere and stimulus frequency as independent variables, respectively. To compare the differences between the conditions, post hoc multiple comparisons were performed using Bonferroni adjusted t-tests. All statistical analyses were performed at p \u2264 0.05.We performed three analyses. First, to confirm the trend that the amplitude and ITPC of oscillations decrease with increasing harmonic number, Post/Pre ratios from the first to fifth harmonics were compared without distinguishing the left and right hemispheres in five conditions (not the 40-Hz condition) using one-way repeated-measures analysis of variance (ANOVA) with harmonic as an independent variable. Here, the first harmonic was used as the fundamental stimulus frequency. The integer frequencies closest to the harmonic frequencies were used for the analysis under the 6.67- and 13.3-Hz conditions. Then, a two-way ANOVA was performed with hemisphere and PrePost as independent variables, to compare Pre and Post at 4\u2013100 Hz under each condition to examine whether a distinct signal-to-noise ratio by harmonics was obtained for amplitude and ITPC, respectively. F = 16.35, p = 4.97 \u00d7 10\u201313] and the ITPC . Although the ITPC was smallest for the fifth harmonic, the first to third harmonics did not show a clear gradual decrease, which appeared to depend on the specific increase at 40 Hz  = 25.17, p = 7.50 \u00d7 10\u201320] and the ITPC . However, the data from each sound stimulus did not follow this trend.The train of six pure tones induced an increase in the amplitude and ITPC of oscillations at almost all stimulus frequencies and some of its harmonic frequencies. The ratio of the average amplitude and ITPC relative to the baseline (Post/Pre ratio) for each frequency in all conditions are shown in at 40 Hz . Therefop < 0.012) and second  harmonics at 40 Hz, respectively, but not around the first harmonic  revealed that PrePost significantly affected the oscillation amplitude around the first harmonic under the 6.67, 8, 10, and 40 Hz conditions. Under these four conditions, no significant increase in the amplitude of other harmonics was observed. In the 13.3 and 20 Hz conditions, a significant increase in the amplitude was observed around the third , 8 Hz , 10 Hz , 13.3 Hz , 20 Hz , and 40 Hz conditions   = 6.46, p = 1.09 \u00d7 10\u20134], 13.3 Hz , 20 Hz , and 40 Hz conditions . Conversely, the harmonic did not play a role in determining the ITPC in the 8 and 10 Hz conditions (p > 0.067). The ITPC in the right hemisphere was significantly greater in the 20 Hz  and 40 Hz conditions . There were no interaction effects in all conditions (p > 0.34). Post hoc multiple comparisons using Bonferroni adjusted t-tests revealed the following results: in the 6.67-Hz condition, the first harmonic was significantly higher than the fifth, seventh, and eighth (p < 0.030) harmonics, but the sixth harmonic (40 Hz) was not significantly different from the other harmonics (p > 0.16). In the 13.3-Hz condition, the third harmonic (40 Hz) was significantly increased compared to the second and fourth harmonics (p < 0.003). In the 20-Hz condition, the harmonics significantly increased in the order of the third, first, and second (40 Hz) (p < 0.001), and in the order of the second and first in the 40-Hz condition (p < 0.001).A significant increase in ITPC was observed around 40 Hz for all conditions: in the 6.67 Hz  . We subsF = 4.54, p = 0.044] and stimulus frequency , but no interaction effect . All the amplitudes at 40 Hz in the three conditions showed right hemisphere dominance. Post-hoc tests showed that the amplitude at 40 Hz was significantly increased in the order of 13.3, 20, and 40 Hz conditions (p < 0.001). Regarding the ITPC, the results showed a significant difference in stimulus frequency , but not between hemispheres . No interaction was detected between stimulus frequency and hemisphere . The post-hoc tests showed that the 40-Hz condition was the highest (p < 0.022), followed by the 20 and 13.3 Hz conditions. There was no significant difference between the 20 and 13.3 Hz conditions (p = 0.16), but they were significantly greater than the 6, 8, and 10 conditions (p < 0.001). There were no significant differences between the 6, 8, and 10 Hz conditions (p > 0.99).There was a significant increase in amplitude around 40 Hz for the 13.3, 20, and 40 Hz conditions and for all conditions in the ITPC. The Post/Pre ratios of amplitude and ITPC at 40 Hz under these conditions were compared, respectively. In case of the amplitude, two-way ANOVA (hemisphere \u00d7 stimulus frequency) revealed a significant difference in hemisphere [p < 0.016), at 31 Hz in the 13.3-Hz condition (p = 0.031), and at 30\u201332 Hz in the 40-Hz condition (p < 0.044) (p < 0.017), at 12\u201314 Hz in the 8-Hz condition (p < 0.003), at 14 and 15 Hz in the 10-Hz condition (p < 0.025), at 6\u201311 and 17\u201321 Hz in the 13.3-Hz condition (p < 0.017), at 6\u201315 and 26\u201328 Hz in the 20-Hz condition (p < 0.044), and at 6\u201312 and 14\u201316 Hz in the 40-Hz condition (p < 0.014)  . These r< 0.044) . Additio< 0.014) .In this study, with particular attention to harmonics, we examined brain oscillations over a wide frequency range during auditory stimulation between 6.67 and 40 Hz that have the harmonic at 40 Hz. Harmonics were identified in all conditions. In particular, the increase in ITPC by harmonics was detected at more frequencies than the increase in amplitude under all conditions. We first evaluated whether the oscillatory responses decreased as the harmonic number increased . HoweverIn the 6.67, 8, and 10 Hz conditions, the harmonic increases in ITPC were observed over a wide frequency range, but there were no harmonic increases in amplitude. The amplitudes at the stimulus frequency in these three conditions were significantly increased, but their Post/Pre ratios were very small compared to those in ITPC. It could be suggested that the harmonic increases in amplitude did not appear due to lower relative changes in amplitude at the stimulus frequencies. In a study examining the test-retest reliability of the ASSR using MEG, ITPC exhibited high reliability compared to spectral power . In addiIn some conditions, the oscillatory responses did not follow the phenomenon of decreasing as the harmonic number increased, except the 40-Hz harmonic. In the 13.3-Hz condition, ITPC did not increase with stimulus frequency, but it did increase significantly not only in the third (40 Hz) but also in the second and fourth harmonics. This finding indicated that the special activation of the oscillation by harmonics affected not only 40 Hz but also the surrounding frequency bands. Conversely, ITPC under the 10-Hz condition showed that the second harmonic (20 Hz) was larger than the fundamental, although there was no significant difference between the fundamental and the harmonics. A similar phenomenon was observed in the 6.67-Hz condition, where the ITPC at the third (20 Hz) harmonic was slightly larger than the ITPC at the second harmonic. In addition, in the 8 and 10 Hz conditions, sporadic significant increases in ITPC were observed at the eleventh (88 Hz) and seventh (70th) harmonic, respectively. These trends may reflect a previous study that showed peaks in the phase response of the ASSR at approximately 20, 40, and 80 Hz . It has in vitro study demonstrated the inhibition of low-gamma oscillations by a 40-Hz circuit (The 13.3 and 20 Hz conditions showed a specific increase in 40-Hz oscillations, but the amplitude of oscillations at the stimulus frequency did not show a significant increase. This indicates that these stimuli actually activated some oscillations at subharmonic frequencies of 40 Hz, but the response did not fall in a sufficiently narrow-frequency range to create a prominent peak. Thus, one explanation of the finding could be the non-linearity of the responsible cells . The lac circuit .Our study has several limitations. First, whether the 40-Hz circuit suppresses broadband oscillations in patients with schizophrenia remains unexplored. Therefore, further clinical studies should be conducted to strengthen our hypothesis. Further research using cytological and other biological techniques is also needed to provide evidence that two categories of oscillators interact to generate neural oscillations. The second limitation concerns hemispheric differences. As shown previously , the ampUsing the nature of oscillation harmonics, we identified subharmonics that specifically activate the 40-Hz ASSR. These subharmonics at the beta frequency band were not activated at their own stimulus frequency and could have been suppressed by the resonant 40-Hz circuit. These findings may provide novel insights into the pathophysiology of various neuropsychiatric disorders associated with abnormalities in the 40-Hz ASSR.The original contributions presented in this study are included in the article/supplementary material, further inquiries can be directed to the corresponding author.This study was approved by the Ethics Committee of the National Institute for Physiological Sciences, Okazaki, Japan and was conducted in accordance with the Declaration of Helsinki. The patients/participants provided their written informed consent to participate in this study.SS and KI designed the work and drafted the manuscript. SS, TT, TK, NT, MN, and KI performed the experiments. SS analyzed the data. KO and TS provided valuable critical input on the manuscript. All authors read and approved the manuscript."}
{"text": "Computational and Mathematical Methods in Medicine has retracted the article titled \u201cHand Gesture of Recognition Pattern Analysis by Image Treatment Techniques\u201d [hniques\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifi"}
{"text": "In situ Raman investigation of the phase transition of NaVO2F2 under variable temperature conditions\u2019 by Sa Zhang et al., RSC Adv., 2021, 11, 23550\u201323556, https://doi.org/10.1039/D1RA02827H.Retraction of \u2018 RSC Advances article due to issues with the equipment used during the research and the resulting errors due to an unstable temperature control system.We, the named authors, hereby wholly retract this 2F2. The temperature change was controlled by a THMS600 high and low-temperature sample stand. After the publication of this research, the unstable temperature was found to be caused by the system of the THMS600 sample stage, which lead to the temperature error in the analysis of phase transformation during the heating process. This has led to errors in the analysis, and therefore the conclusions of this paper are not supported. The authors also regret that the funding information was incorrectly shown in the original article.A Raman spectrometer was used for the testing outlined in this research, utilising coupled variable temperatures to investigate the phase transition of NaVOSigned: Sa Zhang, Yan Li, Liuqing Huang, Liuying Huang and Xuetao Luo, 23rd June 2022.RSC Advances.Retraction endorsed by Laura Fisher, Executive Editor,"}
{"text": "Applied Bionics and Biomechanics has retracted the article titled \u201cPrognostic Role of Biomarkers for Pulmonary Arterial Hypertension Associated with Bronchopulmonary Dysplasia in Extremely Premature Infants\u201d [Infants\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifiThe authors do not agree to the retraction."}
{"text": "Ipadeola  The authors regret that one of the funders of this work was omitted in the Acknowledgements section of the original publication. The correct acknowledgements are as follows:This work was supported by the Qatar University High Impact Internal Grant (QUHI-CAM-22/23-550), Qatar National Research Fund (NPRP13S-0117-200095) and NRF/DSI/Wits SARChi Chair in Materials Electrochemistry and Energy Technologies (MEET) (UID No. 132739). The statements made herein are solely the responsibility of the authors. The authors are grateful to the Environmental Science Center (ESC), Qatar University, for the ICP-OES analysis. The publication of this article was funded by Qatar National Library.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "The authors wish to make corrections to their paper .In the original publication, there was a mistake in the legend for Blood parameter analysis showed no significant differences between mock-treated and ObiDi/SO1861-treated mice indicating that the conjugate is well tolerated . If abno"}
{"text": "Computational and Mathematical Methods in Medicine has retracted the article titled \u201cArtificial Intelligence Assists the Construction of Quantitative Model for the High-Quality Development of Modern Enterprises\u201d [rprises\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifiThe authors do not agree to the retraction."}
{"text": "Upon publication, the Cureus editorial office noticed that a key financial relationship was not disclosed. The Financial Relationships section of the\u00a0Ethics Statement and Conflict of Interest Disclosures has therefore been updated to include the following:Iani Silveira declare(s) employment from Bella Vida Aesthetics. Iani Silveira is the owner of Bella Vida Aesthetics, which advertises the Bella Vida Instant Brazilian Butt Lift procedure as a paid service.When contacted, the authors were in agreement that this relationship be disclosed via formal correction. The Cureus editorial office and the authors apologize that this oversight was not identified and addressed prior to publication."}
{"text": "Please see:"}
{"text": "Cancer Gene Therapy 10.1038/s41417-018-0068-4, published online 01 February 2019Retraction of: The Editor-in-Chief has retracted this article at the authors\u2019 request. After publication, the authors noticed that incorrect images were used in Fig. 2E to inform their conclusions. The authors therefore no longer have confidence in the presented results and data reproducibility.ZY and XJ agree to this retraction. SY and HY have not responded to any correspondence from the editor or publisher about this retraction. The Editor has not been able to obtain a current email address for HZ."}
{"text": "Following publication of the original article , the ord1,2,3, Jiaqi Li1,3, Yun Luo1,3, Wei Zhang1,3*Jiaxun Jiao1Department of Spinal Surgery, The Third Hospital of Hebei Medical University, Shijiazhuang 050051, People\u2019s Republic of China.2Department of Spinal Surgery, Harrison International Peace Hospital, Hengshui 053000, Hebei, People\u2019s Republic of China.3The Key Laboratory of Orthopedic Biomechanics of Hebei Province, The Third Hospital of Hebei Medical University, Shijiazhuang 050051, People\u2019s Republic of China.All authors agree to these corrections and apologize for the inconvenience caused.The original article has been revised."}
{"text": "Retraction Note: J Ovarian Res 13, 127 (2020)10.1186/s13048-020-00723-7The Editors-in-Chief have retracted this article. After publication, concerns were raised regarding the flow cytometry plots presented in the article. Specifically:In Fig. 3c, the two miR-545-3p mimic panels appear highly similar.Fig. 5c OVCAR3 middle panel appears highly similar to Fig. 6c MG-63 middle panel in .Fig. 6C OVCAR3 middle panel appears highly similar to Fig. 4b MG-63 right panel in .The two articles also exhibit highly similar study design, data presentation style and western blot appearance despite being written by different author groups.The authors have stated that they uploaded the wrong images from third party equipment. The Editors-in-Chief therefore no longer have confidence in the presented data.None of the authors have responded to any correspondence from the editor or publisher about this retraction notice."}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors\u2019 attention by a concerned reader that certain of the western blotting data shown in Fig. 6A were strikingly similar to data that had appeared in different form in another article by different authors in a different research institution. Owing to the fact that the contentious data in the above article had already been published elsewhere prior to its submission to"}
{"text": "Journal of Healthcare Engineering has retracted the article titled \u201cRegulatory Networks of Prognostic mRNAs in Pediatric Acute Myeloid Leukemia\u201d [eukemia\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifiThe authors do not agree to the retraction."}
{"text": "S2 in\u00a0;in Fig.\u00a03, the Heart/Saline and Heart/Micelles panels partially overlap, respectively, with Heart/DEX-SS-IND and Heart/Saline panel in Fig.\u00a07 in\u00a0;in Fig.\u00a04a, the TGN/cy3 micelles panel in 2.0\u00a0h line overlaps with the SA-DEX-CUR panel in the e-Selectin line in Fig.\u00a04 in\u00a0[2O2 and H2O2\u2009+\u2009TPP-MLT overlap, respectively, with panels PTX and FA@PPMoV@PTX in Fig.\u00a04B in\u00a0[in Fig.\u00a05D, panels HThe Editors-in-Chief have retracted this article. After publication, the following concerns were raised:Following these concerns author Jingbo Hu contacted the journal requesting a retraction. They did not respond to the editor's request to share original data. The Editors-in-Chief therefore no longer have confidence in the integrity of the data in this article.Jingbo Hu agrees to this retraction. The other authors have not responded to any correspondence from the editor/publisher about this retraction."}
{"text": "Retraction Note: J Exp Clin Cancer Res 37, 121 (2018)https://doi.org/10.1186/s13046-018-0794-3The Editor-in-Chief has retracted this article at the corresponding author's request. After publication, concerns were raised regarding image overlap between Fig. 4g and an article from a different group .The authors provided partial raw data, which was insufficient to address the image overlap concerns. Additionally, the raw data provided for Fig. 6d revealed that the images representing the lncASO and SRCAP KO groups may have originated from a single sample. Similarly, the images representing the two GRP107 KO groups also may have originated from a single sample.A further investigation by the publisher has revealed that there is no statement of Ethics approval for the use animals in the article. Additionally, in Fig. 6b, a number of data points refer to tumours that weigh 2.8-3 g, which exceed the recommended tumour weight limit of 10% of initial bodyweight. The authors have been unable to retrieve the original animal ethics approval documents. Xinke Zhou has stated on behalf of all authors that none of the authors agree to this retraction."}
{"text": "After consulting the authors, they agreed with the Editor's decision that this paper should be retracted. The Editor apologizes to the readership for any inconvenience caused.Following the publication of the above paper, a concerned reader drew to the Editors' attention that certain of the western blot data shown in Figs. 4B and 6D, and the scratch-wound assay data shown in Fig. 2D, were strikingly similar to data that had already appeared in previously published papers written by different authors at different institutes. Furthermore, there appeared to be anomalies associated with the cell invasion assay data portrayed in Fig. 2E. Having considered the issues identified, the Editor of"}
{"text": "Dear Editor,The recent report on \u201cOral manifestations of dengue viral infection\u201d is very interesting.The authors declare no conflicts of interest."}
{"text": "Gng8 within 19q13.32 from where deletions have been associated with intellectual disability [Gng8 knockout mouse highlighting a putative role for Gng8 in aspects of spatial and long-term memory [G-protein gamma 8 (Gng8), sometimes referred to as \u03b38(olf), belongs to the family of gamma subunits of heterotrimeric G proteins , 2. Whilm memory . While IGng8 KO mice and behavioural analysis in the Morris Water maze showed intact spatial learning but attenuated spatial memory when mice were tested in the absence of the escape platform . Close scrutiny of Fig. 3d however suggests all mice are actually avoiding the target quadrant (only ~6% WT and ~4% KO time in target quadrant) after spatial learning\u2014this is most unusual. A similar experiment is repeated  that includes pharmacological interventions. In this dataset for the probe trial , the WT vehicle show ~30% time in the target quadrant, with Gng8 KO mice showing reduced time (~20%). It is not clear why the two datasets  are so different from each other.Characterisation of the Gng8 KO mice acetylcholine (ACh) levels were reduced in the medial habenula (mHb) and choline acetyltransferase (ChAT) was reduced in both the mHb and the interpeduncular nucleus (IPN), especially IPR and IPC. The team subsequently demonstrated impaired high frequency stimulation induced hippocampal long-term potentiation suggesting that \u201cdecrease in cholinergic activity of the MHb\u2013IPN pathway in Gng8 KO mice could affect hippocampal synaptic plasticity\u201d. While on the surface this appears a perfectly reasonable hypothesis, the devil is in the detail. The link between the mHb \u2013 IPN pathway and the hippocampus (HC) was suggested to be via a direct IPN \u2013 HC pathway. Critically, the authors stated \u201cTo examine cholinergic projection from the IPN to the HC, FG retrograde tracer was injected into the HC, and immunoreactivity of FG and ChAT in the IPN was quantified. Manders\u2019 coefficient was 0.4438, and Costes P value was 0.9863 . These data indicated that 44.38% of IPN\u2013HC efferents are cholinergic neurons\u201d. Usually such a conclusion would also be supported by cell counts. Moreover, in the discussion the authors state \u201cAlthough the IPN sends minor efferent to the HC\u2026, 56.30% of these IPN efferents were cholinergic\u2026\u201d.Focusing on the habenula and its output targets, the authors showed that in Cholingeric neurons in the mHb innervate the IPN via the fasciculus retroflexus (FR) [as reviewed in . Lee et Indeed, evidence for cholinergic neuronal cell bodies in IPR or IPC (the focus of the current study) is therefore lacking. For transparency, in rat brain, there is a report of VAChT in a scattering of cells in the lateral aspects of IPN , althougFrom the data presented, it is therefore difficult support the rather definitive conclusion that \u201c44.38% of IPN\u2013HC efferents are cholinergic neurons\u201d. It is however distinctly possible that the cells in the IPN that project to the HC receive a cholinergic input from mHb, and reduced cholinergic transmission at mHb\u2014IPN synapses could perceivably impact the activity of IPN\u2014HC neurons and thereby contribute to the phenotype observed. Nevertheless, in rats Gng8 is not restricted in expression to the habenula\u2014interpeduncular system  and ther"}
{"text": "Computational and Mathematical Methods in Medicine has retracted the article titled \u201cEffect of Health Education Combined with Dietary Guidance on Nutritional Indicator, Immune Level, and Quality of Life of Patients with Pulmonary Tuberculosis\u201d [culosis\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifi"}
{"text": "An error was present in the published article in the final sentence of the Abstract. The correct sentence should read as follows:Additionally, the methodological capability of PFG NMR for measuring self-diffusion coefficients of long-chain hydrocarbons (up to C19) confined to narrow mesopores of catalytically active materials is demonstrated for the first time.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "There was an error in the original publication . **IRB 12. Materials and Methods**, **2.1. Study Population**:A correction has been made to ****IRB 19079.02**There was an error in the original publication . **Novem2. Materials and Methods**, **2.1. Study Population**:A correction has been made to ****September 2019**There was an error in the original publication . **IRB 1Institutional Review Board Statement**:A correction has been made to ****IRB 19079.02**The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. The original publication has also been updated."}
{"text": "Scientific Reports 10.1038/s41598-021-00279-6, published online 25 October 2021Editorial Expression of Concern to: The Editors are issuing an editorial expression of concern to alert readers that this article shows indication of irregularities in authorship. Concerns have been raised about the expertise of some of the authors not matching the subject matter of this article. Authors provided explanations regarding addition of authors during submission process, but they did not sufficiently document contributions of all authors.https://zenodo.org/record/6791248Additionally, the code used to generate the results had not been previously made available. It is now deposited in the zenodo repository and can be found at: Rahmad Syah, Marischa Elveny, Mahyuddin K. M. Nasution, Vadim V. Ponkratov and Meisam Babanezhad disagree with this Editorial Expression of Concern. Mariya Yurievna Kuznetsova and Andrey Leonidovich Poltarykhin did not respond to the correspondence from the Editors."}
{"text": "Article title: Design, synthesis and biological evaluation of 2-((4-sulfamoylphenyl)amino)-pyrrolopyrimidine derivatives as CDK inhibitors Authors: Bo Yang, Yanni Quan, Wu-li Zhao, Yingjie Ji, Xiaotang Yang, Jianrui Li, Yi Li, Xiujun Liu, Ying Wang, Yanping Li Journal:Journal of Enzyme Inhibition and Medicinal ChemistryBibliometrics: Volume 38, Number 1 DOI:https://doi.org/10.1080/14756366.2023.21692822 group for compound 2g in The authors would like to point out that the wrong version of"}
{"text": "Computational Intelligence and Neuroscience has retracted the article titled \u201cLncRNA BC083743 Silencing Exacerbated Osteoporosis by Regulating the miR-103-3p/SATB2 Axis to Inhibit Osteogenic Differentiation\u201d [Following an investigation conducted by the Hindawi Research Integrity team , signifi"}
{"text": "Computational and Mathematical Methods in Medicine has retracted the article titled \u201cA Diagnostic Model of Volleyball Techniques and Tactics Based on Wireless Communication Network\u201d [Network\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifiThe authors do not agree to the retraction."}
{"text": "RSC Advances article due to concerns with the reliability of the data.The Royal Society of Chemistry hereby wholly retracts this In Fig. 2D, the \u2018HT-1376/Control group\u2019, \u2018HT1376/MALAT1 scramble\u2019, \u2018253J/Control group\u2019 and \u2018253J/MALAT1 scramble\u2019 panels all contain the same duplicated section, which shows that all 4 images come from the same image.There are unexpected similarities within the background of the GAPDH panel in Fig. 2F, indicating that the bands may have been placed onto a false background.The authors were asked to provide the raw data for this article, but did not respond. Given the significance of the concerns about the validity of the data, and the lack of raw data, the findings presented in this article are not reliable.The authors were informed but have not responded to any correspondence regarding the retraction.RSC AdvancesSigned: Laura Fisher, Executive Editor, Date: 18th August 2022"}
{"text": "This Expression of Concern is for the above article, published online on May 1, 2020 in Wiley Online Library, and has been published by agreement between the journal Editor\u2010in\u2010Chief, Dr. John Wagner, and John Wiley & Sons, Inc. The expression of concern has been agreed to due to concerns about the validity of the Western blot and qPCR data presented in the article, along with similarities to other CTS articles that have been retracted or for which an expression of concern has been published. In accordance with Committee on Publication Ethics (COPE) guidelines, the journal has asked all authors and their institutions for raw data that may answer some of the questions raised. Upon multiple requests, the authors have submitted raw data for the editorial team\u2019s interpretation. The editorial team found the provided data inconclusive. As a result, the journal has decided to issue an Expression of Concern to readers. Readers should interpret the information presented in the article with due caution."}
{"text": "The Publisher retracts the cited article.Following publication, the publisher uncovered evidence that false identities were used in the peer-review process. The assignment of a fake reviewer was confirmed by an investigation, conducted in accordance with Frontiers\u2019 policies and the Committee on Publication Ethics (COPE) guidelines.The investigation also uncovered concerns about the presentation and validity of the data in the article that normally would have led to a rejection. When contacted, the authors failed to provide a data set that adequately supports the reported conclusions.The authors do not agree to this retraction.This retraction was approved by the Chief Editors of Frontiers in Cell and Developmental Biology and the Chief Executive Editor of Frontiers."}
{"text": "The authors wish to make a correction to this paper . We inad\u201cAdditionally, Kusumi et al. introduced CLEM using semithin (1 \u03bcm) cryosections at \u221265 to \u221275 \u00b0C in the backscattered electron (BSE)-mode scanning electron microscope .\u201dNewly added reference as [15] in original paper, the order of some reference citations has been adjusted correspondingly.The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "DOI: 10.1039/D0RA09265G.Correction for \u2018Pickering-emulsion-templated synthesis of 3D hollow graphene as an efficient oil absorbent\u2019 by Nurul Aqilah Pohan  The author regrets that the funding information was incorrectly shown in the Acknowledgements section of the original manuscript. The corrected funding acknowledgements are as shown below.The authors would like to thank the Ministry of Education of Malaysia for funding this study through grant no: FRGS/1/2018/STG01/UPM/02/11. Special thanks are extended to NanoMalaysia Berhad and Tex Cycle Technology (M) Berhad. Nurul Aqilah Pohan would like to thank the Ministry of Education of Malaysia for the Special Graduate Research Allowance Scheme.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "In the original publication , a formaThe authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "Sci., 2021, 12, 14740\u201314751, https://doi.org/10.1039/D1SC04265C.Correction for \u2018The solvation structure, transport properties and reduction behavior of carbonate-based electrolytes of lithium-ion batteries' by Tingzheng Hou  The original version of this manuscript contained typographical errors in the Conclusions. The anion\u2013solvent exchange mechanism should be referred to as \u201cexit-entry\u201d type, not \u201centry-exit\u201d type.The sentence \u201cWe also reveal an anion\u2013solvent exchange mechanism as \u201centry-exit\u201d type, providing a dynamic perspective of ion transport in electrolytes\u201d should therefore be \u201cWe also reveal an anion\u2013solvent exchange mechanism as \u201cexit-entry\u201d type, providing a dynamic perspective of ion transport in electrolytes.\u201dThe Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "The authors regret a typing error in the code used in the analysis of the dataset, which affected the values included in supplementary table \u2018lec_top_tables.csv\u2019. This table is relevant to the paragraph \u201cThe top-ranked differentially expressed genes from the linear model \u2026 another file listing such genes from the model fitted using LEC data (Supplementary File 2: lec_top_tables.csv)\u2026\u201d. The GitHub repository containing the relevant code and table has been updated with the correct results. Any further results are unaffected. The authors would like to apologise for any inconvenience caused."}
{"text": "This has now been corrected. The authors regret this error and apologize for any confusion that it has caused.On examining the online pdf, the authors discovered a mistake in two of the labels in the graphical abstract. The labels \""}
{"text": "There was an error in the original publication . We statSection 3, Paragraph 3: \u201cNone of the questionnaires stated how long it takes to complete each questionnaire\u201d has been removed;Section 4, Paragraph 1: \u201cNone of the questionnaires stated how long it takes to complete each questionnaire, which would affect the practicality of using the questionnaires in day-to-day practice\u201d has been removed; andSection 4, Paragraph 3: \u201cAlthough none of the questionnaires stated how long it takes to complete each questionnaire\u201d has been removed.The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. The original publication has also been updated."}
{"text": "Breast core biopsies show a diffuse sheet of neoplastic cells with round nuclear contour, open chromatin, eccentric nuclei with distinct nucleolus and relatively abundant eosinophilic cytoplasm Figure\u00a0, immunogThe authors declare that they have no conflict of interest.The authors received no specific funding for this work.This case followed the University Health Nerwork and patients' ethics."}
{"text": "The Publisher retracts the cited article.Following publication, the publisher uncovered evidence that false identities were used in the peer-review process. The assignment of fake reviewers was confirmed by an investigation, conducted in accordance with Frontiers\u2019 policies and the Committee on Publication Ethics (COPE) guidelines.The investigation also uncovered concerns about the presentation and validity of the data in the article that normally would have led to a rejection. When contacted, the authors failed to provide a data set that adequately supports the reported conclusions.The authors do not agree to this retraction.This retraction was approved by the Chief Editors of Frontiers in Physiology and the Chief Executive Editor of Frontiers."}
{"text": "The following scientists assisted the journal by reviewing manuscripts during the period November 1, 2021 to October 31, 2022.We gratefully acknowledge their critical evaluation and valuable assistance in selecting articles for publication."}
{"text": "There was an omission in theacknowledgment in the original manuscript. The corrected acknowledgmentis given below.The authors sincerely thank the Postdoctoralinnovative talentssupport program in China (BX2021374) and the National Natural ScienceFoundation--Youth Foundation (5210040269) for providing financialsupport, and Key Supporting Projects of Joint Fund of National NaturalScience Foundation of China (U21B2069)."}
{"text": "The authors have checked their original paper, and realize that the sequence of this shRNA was written incorrectly in the paper; the sequence for the shRNA targeting the gene NOB1 should have been written as: GCTTGCACTCACATACCAGTTCTCGAGAACTGGTATGTGAGTGCAAGC.Subsequently to the publication of this paper, an interested reader drew to the authors\u2019 attention that, on p. 2174 in the Materials and methods section (subsection \u201cFurthermore, the published version of Molecular Medicine Reports for allowing them the opportunity to publish this corrigendum, and apologize to the readership for any inconvenience caused.The revised version of"}
{"text": "Retraction Note: J Exp Clin Cancer Res 39, 190 (2020)https://doi.org/10.1186/s13046-020-01657-0Fig. 1C: the tumour-IHC:IMP3 panel appears very similar to the tumour-SAT1 panel in Fig 2N in a paper by different authors that was under submission at the same time [Fig. 2B: the LNCap IMP3 blot appears very similar to the SK-KEP-1 ACSL4 blot in Fig 2B in a previously-published paper by different authors [Fig. 2F contains multiple panels that seem to overlap with panels in Fig 1C a previously-published paper by different authors , Fig 1D Fig. 4A: the SMURF1 blot appears very similar to the N-Cahedrin blot in a paper by different authors that was under submission at the same time .Fig. 6F contains two tumours that appear similar to those in Figs 2M and 7H in in a previously-published paper by different authors [The Editor in Chief and all authors have retracted this article. After publication, concerns were raised about the following issues with the images:The authors supplied the raw data, but in view of the multiple nature of the overlaps, the Editor in Chief has lost confidence in the integrity of the results of the article. All authors agree with this retraction."}
{"text": "Ischemic heart disease (IHD) and heart failure (HF) remain the leading causes of death worldwide , despiteJCM team.As a Guest Editor, I thank the authors, reviewers, and the"}
{"text": "Explosive volcanic eruptions eject a gas-particle mixture into the atmosphere. The characteristics of this mixture in the near-vent region are a direct consequence of the underlying initial conditions at fragmentation and the geometry of the shallow plumbing system. Yet, it is not possible to observe directly the sub-surface parameters that drive such eruptions. Here, we use scaled shock-tube experiments mimicking volcanic explosions in order to elucidate the effects of a number of initial conditions. As volcanic vents can be expected to possess an irregular geometry, we utilise three vent designs, two \u201ccomplex\u201d vents and a vent with a \u201creal\u201d volcanic geometry. The defining geometry elements of the \u201ccomplex\u201d vents are a bilateral symmetry with a slanted top plane. The \u201creal\u201d geometry is based on a\u00a0photogrammetric 3D model of an active volcanic vent with a steep and a diverging vent side. Particle size and density as well as experimental pressure are varied. Our results reveal a strong influence of the vent geometry, on both the direction and the magnitude of particle spreading and the velocity of particles. The overpressure at the vent herby controls the direction of the asymmetry of the gas-particle jet. These findings have implications for the distribution of volcanic ejecta and resulting areas at risk. Explosive volcanic eruptions eject gas and pyroclasts at high velocity and temperature into the atmosphere. The related threat to life and infrastructure is a consequence of the eruption\u2019s style and magnitude. In proximal areas (tens of metres to few kilometres), volcanic ballistic projectiles can inflict injury and destruction of property \u2009>\u2009atmospheric pressure (Patmosphere)) starting jets  can substantially alter the jet dynamics.Multiphase jets result from magma fragmentation following deformation and gas expansion and occur over a wide range of eruption styles, e.g. Strombolian, Vulcanian and Plinian eruptions  has an internal diameter of 28\u00a0mm and a volume of 127.4 cm3. Upon intended failure of the uppermost diaphragm, the diaphragm(s) below go outside their stability field, open, and pressure equilibration initiates. The associated rapid decompression of the autoclave allows the gas to expand. The associated gas flow accelerates the particles; the gas-particle mixture is ejected through a vent into the low-pressure section, a 3\u00a0m high stainless-steel tank at ambient conditions, sitting above a 35\u00a0cm high transparent Perspex cylinder.The setup consists of a high- and low-pressure section, separated by diaphragms. Two copper diaphragms (each will break at\u2009~\u20094.6\u00a0MPa) or three iron diaphragms (each will break at\u2009~\u20096.1\u00a0MPa) were used for the incremental pressurisation to the final autoclave pressure of 8 and 15\u00a0MPa, respectively. The autoclave  or 15\u00b0 diverging funnel (fun30) inner geometry, respectively. Accordingly, lateral gas expansion can already start below the vent exit for the diverging vent. The lower vent exit height was always 50\u00a0mm  resembles the geometry of the active S1 vent on Stromboli in May 2019. All vents are not eroded by the jet during experiments and are re-used multiple times.Three different vent geometries were used in this study, with increasing \u201ctopographic complexity\u201d based on the findings of Cigala et al.  and Schmd et al. , where t\u00a0mm Fig.\u00a0. The topAgisoft Metashape. For a detailed description of the field campaign and the processing, refer to Schmid et al.  file, a standard file format used in 3D printing. The software Slic3r was used to convert the STL file into printing instructions (G-code) for the 3D printer by cutting the model into horizontal slices (layers) and the required toolpaths to form the 3D printed model. A Renkforce RF1000 3D printer that was controlled by the Repetier-Host software was used. The model was printed with polylactic acid (PLA) filament with a 0.5\u00a0mm nozzle, a layer thickness of 0.4\u00a0mm and 60% infill density in a honeycomb structure. The printed vent was fixed to a steel vent mount to withstand the applied experimental conditions resulting in a total height of\u2009~\u2009160\u00a0mm. The inner diameter up to the throat of the vent is 28\u00a0mm as in the other vents  and 43\u00a0mm (fun30). The defining geometry element of the S1 vent was the asymmetric divergence with\u2009~\u200910\u00b0 on one side and\u2009~\u200940\u00b0 on the opposing side.During the May 2019 field campaign, aerial imagery was collected by unoccupied aerial vehicle (UAV) of a specific vent  and subsequently, a 3D model was created by Structure from Motion (SfM) photogrammetry using d et al. . The cre3 and 1.4\u00a0g/cm3 for the scoria (SL) and the pumice (LSB), respectively  and six different samples were tested for each vent geometry. The pressures have been selected to allow a direct comparability with earlier studies on gas-particle and gas-only jets with variable vent geometry that have been performed at 5, 8, 15 and 25\u00a0MPa  at the top of the autoclave to trigger the recording system. We recorded the experiments with a high-speed camera (Phantom V711) and a pressure sensor (KISTLER 601A) at the vent exit. All experiments were filmed at 10,000 frames per second (fps) and a resolution of 1280\u2009\u00d7\u2009600 pixels (cyl30 and fun 30), 864\u2009\u00d7\u2009760 pixels  or 960\u2009\u00d7\u2009704 pixels . The field of view was approximately 27\u2009\u00d7\u200913\u00a0cm, 24\u2009\u00d7\u200918 and 25\u2009\u00d7\u200919\u00a0cm, respectively (~\u2009240\u00a0\u00b5m/pixel). The camera was aligned orthogonally to the symmetry plane of the vent and centred on the vent axis. The experiments were analysed over a duration of 15\u201320\u00a0ms. Subsequently, particles continued to leave the vent but the overpressure in the autoclave had been exhausted.Once the experiments were initiated, the instantaneous pressure drop in the autoclave  was recFiji . We measured the particle spreading angle of the gas-particle jets and the particle ejection velocity. The spreading angles reported here are always the maximum spreading angle that was reached during a single experiment. The particle spreading angle is the angular outward deviation from the vertical continuation of the inner autoclave walls. It was measured as a tangent along the edge of the gas-particle jet starting at the vent exit to the upper limit of the field of view. All angles reported below represent averaged values from three repeated measurements. For a qualitative comparison of the temporal evolution of the gas-particle jets and the asymmetry of particle spreading angle, the jet boundary (as defined by the presence of particles) was traced for each experimental condition and subsequently stacked . Each particle was tracked over five still frames, and the average velocity is given for\u2009>\u200925 particles.We exported scaled single frames to manually and optically analyse them with the ed Figs. . The parThe reproducibility of experiments in this experimental setup has been demonstrated in several studies  and 2.21\u2009\u00d7\u2009108 , and for the fun30 vent, it was between 3.58\u2009\u00d7\u2009107  and 3.40\u2009\u00d7\u2009108 . Re for the S1 vent was calculated at 1.90\u2009\u00d7\u2009107  and 1.09\u2009\u00d7\u2009108 . In volcanic eruptions, Re can be between 105 and 108 , Mach number (M) and the Stokes number (St) to describe the fluid flow dynamics and the coupling between gas and particles. The reference quantities of Re and M were calculated following the one-dimensional isentropic theory  and 14.31 (15\u00a0MPa). Volcanic eruptions frequently exhibit jets with M\u2009>\u20091  is the particle\u2019s momentum response in relation to the surrounding flow field, i.e. it describes how well a particle couples to the flow. We calculated St for fully expanded conditions for experiments with 0.5\u20131\u00a0mm and 1\u20132\u00a0mm (of SL and LSB) particles following Carcano et al. . The maxS1 vent, we introduced surface roughness into the system. Based on the findings of Alsoufi and Elsayed  vent side than on the right side. In experiments with the fun30 vent, the maximum spreading angle at the beginning of the gas expansion showed a larger spreading angle on the lower vent side. However, throughout the remaining duration of the experiment, the larger spreading angle was observed on the higher vent side. For experiments with the cyl30 geometry, a larger spreading angle was always measured on the lower vent side.In experiments with identical conditions, the ent Fig.\u00a0. This diS1 vent could not be directly compared with the cyl30 and fun30 vent geometries because of the difference in the vent exit height and the resulting offset in time. However, the spreading angle of the jet emitted through the S1 vent was also asymmetrical, with larger spreading angles on the right (more divergent) vent side than on the left side. The spreading angle measured at the steep side of the vent was small and seemed relatively unaffected by particle size, density or experimental pressure.The jet spreading angle measured for the S1\u2019s left (less divergent) side, where the spreading angle was seemingly unaffected by changing initial conditions.In general, experimental pressure was positively correlated, and particle size and density were negatively correlated with gas-particle jet spreading angle. The vent geometry exerted the strongest control and governed the direction and degree of particle spreading angle asymmetry, manifested in visually inclined jets. The effect of particle size was strongest for the fine particle size fraction Fig.\u00a0a and d. fun30 geometry  vent side. In experiments with the S1 geometry, the particle spreading angle was sub-vertical on the left side of the vent for all experimental conditions and at all time steps. On the right (more diverging) side of the vent, larger spreading angles were observed than on the left vent side. The S1 geometry had a higher vent exit height than the other geometries, which caused a delayed ejection of SL particles visible at t\u2009=\u20092.5\u00a0ms, while LSB particles filled the entire field of view . Furthermore, vent geometry caused the asymmetric distribution of particle velocity, i.e. faster particles on one side of the vent. We observed up to\u2009~\u200960\u00a0m/s velocity difference in experiments with the S1 vent geometry and LSB particles. The higher velocity was measured on the right (more diverging) side of the vent. In experiments with the cyl30 and the fun30 geometry, LSB particles showed a higher velocity on the left (lower) side. In the case of the cyl30 vent at both 8 and 15\u00a0MPa pressure, the fun30 vent was only at 15\u00a0MPa. In experiments with SL particles, no distinctive velocity distribution was observed  accounted for up to\u2009>\u2009100\u00a0m/s (>\u2009200%) higher velocities than SL samples Table , Fig.\u00a06.Gas-particle jets respond to complex vent geometry by exhibiting asymmetric behaviour regarding jet spreading angle and particle velocities. Experimental vent geometry governed the general direction and behaviour of the gas-particle jets, while particle properties and overpressure controlled how well the particles followed the forcing (jet spreading and inclination) exerted by the vent geometry. Once decompression was initiated, the ensuing expansion led to a vertical gas flow within the autoclave. The related drag accelerated particles, thereby transferring a significant portion of the initially stored energy into kinetic energy. The geometric boundary conditions (conduit length or depth of magma surface and the topography) controlled the velocity and residual overpressure of the gas phase at the transition into the atmosphere. If jets were underexpanded at the vent, the lateral gas expansion will act on all particles.cyl30 geometry showed the strongest horizontal expansion and the highest calculated overpressure at the vent exit. Because of the slanted top of the vent, the lateral expansion started first on the left (lower) side of the vent, while the lateral confinement still prevented expansion on the right (higher) side. As a result, the jet exhibited asymmetrical particle spreading angles with larger spreading on the vent\u2019s left (lower) side. In experiments with the fun30 vent, the initial gas expansion started inside the vent, thereby partially accommodating overpressure. Consequentially, the spreading angle was smaller than for the cylindrical geometry. Because of the slanted top, the spreading angle was also asymmetric, with a larger angle on the left (lower) side. As the pressure at the vent further decreased, the gas-particle jet changed its direction and exhibited a larger particle spreading angle on the right (higher) vent side after\u2009~\u20095\u00a0ms. This behaviour was unique for the fun30 geometry and can be linked to the more efficient decompression and lower vent exit pressure  than on the opposing side  side of the vent. As a consequence of the asymmetric divergence angle of S1, the right (more diverging) side of the vent had a higher M and accordingly, higher gas velocities were reached on this side. Within the conduit, the acceleration can be assumed to be uniform and unilateral, but once the gas and particles reached the diverging section, the gas was able to accelerate stronger on\u2009~\u200940\u00b0 side. Coupling between the gas and LSB particles was sufficient enough to be reflected by the high velocities of the particles, whereas the inertia of the SL particles prevented them from being fully accelerated by the gas in the diverging sections of the vents.The difference in particle velocity on either side of the vent was a consequence of the complex vent geometries. In experiments with the fun30 vent geometry exhibited a higher ejection velocity than the other vent geometries. The higher exit-to-critical-area ratio and the higher M facilitated faster gas velocities than in experiments with the cyl30 vent. According to fluid dynamic theory  collapse of eruption columns. In Fig.\u00a0If the characteristic asymmetry element is a varying divergence angle instead of a high and low vent exit side, the preferred direction for volcanic fallout and PDCs will be towards the more diverging side Fig.\u00a0c) as a rOur experimental observations of particle trajectories and jet inclination,Direct eruption observations, as well asPublished numerical models and experimental results, we suggest:In addition to vent geometry, the collapse direction can be affected by the asymmetry of the surrounding crater or topography. Jet and plume flow direction is partially restricted and consequentially deflected back and upwards, locally increasing the bulk density Fig.\u00a0d. The phThe asymmetric gas-particle jet spreading angles can initially encourage entrainment because of the increased surface area of the jet\u2019s boundary layer and \u201cincreased penetration distance\u201d  on the left (lower) vent side than the right (higher) vent side. S1 showed a larger spreading angle and faster particles (for LSB particle) on the side with the stronger divergence. In order of importance, the maximum particle spreading angle had:A negative correlation with particle sizeA negative correlation with particle densityPositive correlation with experimental pressureThe particle ejection velocity had:A negative correlation with particle densityA positive correlation with experimental pressureA negative correlation with particle sizeThe rapid decompression experiments performed in the present study investigated the link between vent geometry, particle size and density, and pressure and their impact on the eruption dynamics. In the laboratory, vent geometry determined the direction of the emitted gas-particle jet. The The results of the scaled laboratory experiments performed here show the significance of vent geometry and the major effect of asymmetry on the ejection of multiphase flows. These findings can be applied to interpret observable volcanic eruptions dynamics. The asymmetry of the vent and/or crater can impact areas affected by proximal and distal volcanic hazards. Furthermore, a comparison of the experimental data with field observations (Schmid et al. Ultimately, we need increasingly complex experiments to explore the link between observable eruption dynamics and the underlying, concealed initial conditions that, to date, have remained beyond direct observation and measurements."}
{"text": "None of the original full blots could be found for any of the published figures despite the paper being published so recently and no explanations were given for the duplicated panels. The authors re-analysed their stored samples and supplied replicate blots and analyses, insisting that the conclusions of the paper remain sound. Raw data for all graphs and other cell images were supplied.The journal concluded that without the original data for all the published figures, we have no option but to retract this paper. This course of action follows the advice set out by COPE (Committee on Publication Ethics), of which Biology Open is a member.All authors agree with this retraction."}
{"text": "Retraction Note: J Exp Clin Cancer Res 36, 190 (2017)https://doi.org/10.1186/s13046-017-0661-7The Editor-in-Chief is retracting this article. Concerns have been raised about the welfare of the mice used in this study. The Editor-in-Chief has not been able to obtain clarification on whether the tumour volume and the humane endpoints in the experiments described were approved by the institutional animal ethics committee. None of the authors has responded to correspondence from the Publisher about this retraction."}
{"text": "Multiple images seem to appear in other manuscripts by unrelated authors:"}
{"text": "The x-axis label for panel D of"}
{"text": "RSC Advances article due to concerns with the reliability of the data in the published article.The Royal Society of Chemistry hereby wholly retracts this Repeating fragments can be observed in the XRD spectrum in Fig. 1D, which indicates that it has been manipulated. In addition, there are a number of identical particles replicated within the TEM image that was used in the graphical abstract suggesting that the image has also been manipulated. Given the significance of the concerns about the validity of the data, the findings presented in this paper are no longer reliable.S. Sudheer Khan opposes this retraction. Rashmi Rani Mishra and Preethy Chandran were contacted but did not respond.RSC AdvancesSigned: Laura Fisher, Executive Editor, th July 2020Date: 28"}
{"text": "Fletcher et al., RSC Adv., 2018, 8, 8999\u20139005.Correction for \u2018Sustained delivery of anti-VEGF from injectable hydrogel systems provides a prolonged decrease of endothelial cell proliferation and angiogenesis  One of the funding sources (NIH) was inadvertently omitted in the published article; the corrected acknowledgements section is shown below.The authors gratefully acknowledge funding support from the Boettcher Foundation (#11219) and the National Institute of Arthritis and Musculoskeletal and Skin Diseases of the National Institutes of Health (#1R03AR068087). The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health or the Boettcher Foundation.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Retraction note to: Mol Cancer 15, 51 (2016)https://doi.org/10.1186/s12943-016-0533-3The Editor in Chief has retracted this article because of significant concerns regarding a number of Figures presented in this work, which question the integrity of the data. The Editor-in-Chief therefore no longer has confidence in the integrity of the data in this article. All authors agree to this retraction."}
{"text": "The authors also apologise for unattributed text overlap in the Introduction and Section 2 with ref. 2b and 4b.The authors apologise that two related references were not cited in the original article. Ref. 2 and 4 should be updated to include the two new references as ref. 2et al. (ref. 2b)1 and Naso (ref. 4b)2 should have been included at the following locations in the original article.Citations to the work of Cardellicchio b should be added to the end of the sentences beginning \u201cIn 1897,\u2026\u201d and \u201cIn 1898,\u2026\u201d. Therefore, the sentences should be changed to \u201cIn 1897, Betti obtained his degree with a thesis on the reaction of methylisoxazolones with aldehydes and co-authored with Roberto Schiff the first two papers of his career.a,b3,4 In 1898, Betti moved to the University of Florence as an assistant of Ugo Schiff, who was founder and director of the Institute of Chemistry.b4\u201dOn page 18467, a citation to ref. 46 since Betti reacted methylmagnesium iodide and benzaldehyde in the presence of N,N-dimethylbornylamine.b2\u201dOn page 18648, the sentence beginning \u201cNoyori considered him\u2026\u201d should be changed to \u201cNoyori considered him to be the real pioneer of asymmetric synthesis,b at the end of the second paragraph, therefore the final sentence beginning \u201cFinally, the base\u2026\u201d should be changed to \u201cFinally, the base was also easily resolved into its optical isomers by means of tartaric acid.b,94\u201dOn page 18648, a citation should be added to ref. 4b at the end of the final sentence of Section 2. The sentence beginning \u201cAddition of a\u2026\u201d should be changed to \u201cAddition of a solution of sodium hydroxide to chloride yielded Betti base 1 (75% yield).b,7,132\u201dOn page 18648, a citation should be added to ref. 2The authors also regret their oversight in omitting to acknowledge the source of the image in Fig. 1. The corrected caption for Fig. 1 is shown below.https://www.liberliber.it/online/autori/autori-b/mario-betti. A version of this image was also originally published in Substantia: An International Journal of the History of Chemistry, 2017, 1(2), 111\u2013121.Fig. 1: Italian Senator Mario Betti. This image was reproduced from The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "The authors regret that errorswere made in the derivation of Supporting Information.The corrected m is the number of C\u03b1 atoms in the segment(the length of the segment), k is the index of thefirst residue of the segment, \u03b8i is the planar angle between i is the dihedral angle defined by atoms i and Ci depend on the kind of respectiveamino-acid residues and the neighboring residues.In M is the multiplicityof the respective term and the coefficients bi,M are parameters.Followingthe correction,"}
{"text": "There is information missing from the Acknowledgments section. It should read as follows:The authors would like to thank the study participants for their time and responses without which this paper would not have been possible to write. We also thank the regional, district, shehia and village authorities where the study was conducted for granting the permission and providing every support to successfully conduct this study. We are grateful to Prof. Jennifer A. Downs of the Center for Global Health, Weill Cornell Medicine, New York, United States of America for her support in conceptualizing the project whose outputs include this paper. We also thank her for the reviews, comments and suggestions on the early drafts of this article. The authors would like to acknowledge that the article included qualitative data designed and collected in Tanzania as part of the study \u201cBringing Down Hurdles for Female Genital Schistosomiasis Access to Care: a Multi-Country Socio-Structural Integrated Approach to Developing a Community-Based Teaching Platform\u201d carried out in Zambia, Tanzania and Malawi, funded by The Task Force for Global Health NTD-SD, and led by Virginia Bond , Humphrey Mazigo  and Khumbo Kalua (Blantyre Institute for Community Outreach (BICO). The views expressed in this publication are those of the authors and not necessarily those of the funding agencies. Its contents are solely the responsibility of the authors and do not necessarily represent the official views of the supporting offices."}
{"text": "In the published publication , there wAffiliation 2. Department of Plastic Surgery, College of Medicine, Yeungnam University, Daegu 38541, KoreaAffiliation 3. Department of Internal Medicine, Division of Endocrinology and Metabolism, College of Medicine, Yeungnam University, Daegu 38541, KoreaTae-gon Kim, Jun Sung Moon and Seung Min Chung were not included as authors in the original publication. The corrected Author Contributions Statement appears here.Author Contributions: Conceptualization, C.H.P. and I.W.; data curation, H.S. and J.P.; methodology, T.-g.K., J.S.M. and S.M.C.; investigation, T.-g.K.; writing\u2014original draft preparation, I.W.; writing\u2014review and editing, H.S.; supervision, C.H.P. All authors have read and agreed to the published version of the manuscript.The authors apologize for any inconvenience caused state that the scientific conclusions are unaffected. The original publication has also been updated."}
{"text": "We, the authors, hereby wholly retract this article due to inaccuracies in the scale bars of Fig. 1b, 4h and 5h and the wrong images being presented in Fig. 5d and e.We, the authors, repeated the experiments and believe that the scientific content and conclusions of the related studies presented in the published paper can be reproduced. However, due to the large number of images, it is not possible to replace the published images with the new figures. Therefore, to protect the rigor of the scientific record, we decided to retract this article on our own initiative.Signed: Dong Ge Tong .th March 2020.Date: 6RSC Advances.Retraction endorsed by Laura Fisher, Executive Editor,"}
{"text": "Journal of Healthcare Engineering has retracted the article titled \u201cLiver Protection Mechanism and Absorption Promotion Technology of Silybin Based on Intelligent Medical Analysis\u201d [nalysis\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifi"}
{"text": "This abstract has been withdrawn"}
{"text": "The authors regret that incorrect details were given for ref. 4 in the original article. The correct version of ref. 4 is given below.0.25Zn0.75Se alloy for space photovoltaics. Sci. Rep., 2022, 12, 12978.M. A. Iqbal, M. Malik, W. Shahid, S. Irfan, A. C. Alguno, K. Morsy, R. Y. Capangpangan, P. V. Pham and J. R. Choi, Ab-initio study of pressure influenced elastic, mechanical and optoelectronic properties of CdThe Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Computational and Mathematical Methods in Medicine has retracted the article titled \u201cIbuprofen Alleviates Acute Pancreatitis\u2013 (AP\u2013) Induced Myocardial Injury by Inhibiting AIM2\u201d [ng AIM2\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifiThe authors do not agree with the retraction."}
{"text": "This abstract was requested to be withdrawn by the authors prior to publication."}
{"text": "There is an error in affiliation 1 for authors Hannah Joyce, Lorraine Fleming, and James A. C. Oliver. The correct affiliation 1 is: Department of Ophthalmology, Dick White Referrals, part of Linnaeus Veterinary Limited, Six Mile Bottom, Cambridgeshire, United Kingdom."}
{"text": "However, these cells were inadvertently labeled as ERCC6GC-iPSCs. In the revised version of Fig. In Fig."}
{"text": "Scientific Reports 10.1038/s41598-017-12369-5, published online 20 September 2017Editorial Expression of Concern to: The Editors are issuing an Editorial Expression of Concern for this Article.After publication concerns were raised with respect to the integrity of the magnetic data reported. Editors contacted the Authors to request the raw data, but the corresponding author could not be reached and other Authors informed the journal that they had not been involved in the data collection. Editors subsequently contacted the University of Utah, which confirmed that the raw data for this part of the study are not available. Consequently, readers are advised to interpret the results and conclusions presented in this Article with caution.Berardi Sensale-Rodriguez agrees to this Editorial Expression of Concern. Barun Gupta, Shashank Pandey, Anjali Nahata, Sivaraman Guruswamy & Ajay Nahata have not responded to correspondence about this Editorial Expression of Concern."}
{"text": "All the authors agree to the publication of this corrigendum, and are grateful to the Editor of"}
{"text": "RSC Advances article due to concerns with the reliability of the data in the published article. The authors confirmed that the western blot images in Fig. S3A had been inappropriately manipulated. Given the significance of the concerns about the validity of the data, the findings presented in this paper are no longer reliable.The Royal Society of Chemistry, with the agreement of the named authors, hereby wholly retracts this Fang Liu, Jing Wang and Xiu-Wei Yang were contacted but did not respond.Signed: Qi Zhao, Rui Yang, Dan-Dan Hu and Fei LiDate: 23rd January 2023RSC AdvancesRetraction endorsed by Laura Fisher, Executive Editor,"}
{"text": "GABRA1, GABRB2 and GABRG2 define the genetic landscape of defects of GABAA receptors, Brain Communications, Volume 3, Issue 2, 2021, fcab033, https://doi.org/10.1093/braincomms/fcab033This is a correction to: Ciria C. Hernandez, XiaoJuan Tian, Ningning Hu, Wangzhen Shen, Mackenzie A. Catron, Ying Yang, Jiaoyang Chen, Yuwu Jiang, Yuehua Zhang, Robert L. Macdonald, Dravet syndrome-associated mutations in GABRB2 mentioned in the article have been reported previously. A reference to the previous report has been added.In the originally published version of this manuscript, a reference was omitted. The authors have added a clarification that the three cases of"}
{"text": "In addition, the \u2018blank\u2019 and \u2018miR-control\u2019 panels in Fig. 6A also appeared to contain overlapping data.Oncology Reports has agreed that this paper should be retracted from the Journal, and apologizes to the readership for any inconvenience caused.Independently of the issues that were raised by the interested reader, the authors themselves requested that their paper be retracted on account of having identified some problems with the presentation of various of the figures, and no longer being able to access their original data. The Editor of"}
{"text": "Genetics, 2021, https://doi.org/10.1093/genetics/iyab122In the originally published version of this manuscript, several equations were improperly formatted, thus not conveying information accurately to readers. Additionally, some hyperlinks were omitted. These errors have been corrected."}
{"text": "Antiviral antibody responses to systemic administration of an oncolytic RNA virus: the impact of standard concomitant anticancer chemotherapies. J Immunother Cancer 2021;9:e002673. doi: 10.1136/jitc-2021-002673Roulstone V, Mansfield D, Harris RJ, Victoria Roulstone and David Mansfield are now listed as joint first authors."}
{"text": "Glova  After the 1\u20134 interactions were turned on, the GROMOS force field allowed us to observe the crystallization of n-eicosane with the transition temperature of 270 \u00b1 1 K, see The authors regret that the 1\u20134 Lennard-Jones interactions were not accounted for in the molecular dynamics simulations of Most structural and dynamic characteristics also changed after the 1\u20134 interactions were properly accounted for. Below we present the updated versions of n-eicosane sample anymore and performs rather similarly to other united-atom force fields such as e.g. PYS. The main conclusions of the original publication remain unchanged since the use of all-atom general-purpose force fields was shown to provide a more realistic description for n-eicosane as compared to their united-atom counterparts.Overall, the GROMOS force field does not show abnormal behavior for the The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Antibiotic-resistant bacteria (ARB) and antibiotic-resistant genes (ARGs) in food animals are currently considered emerging contaminants, which seriously threaten public health globally.Original Research Paper , deals with the cecropin-4-derived C18 AMP family in fungal infections against Candida albicans, non-albicans Candida species in extreme low a minimum inhibitory concentration (MIC). Some C18 derivatives proved efficient on clinical isolates of fluconazole (FLZ)-resistant C. tropicalis and also superior to FLZ for killing planktonic C. albicans via damaging the cell structure, retarding hyphae transition, and inhibiting biofilm formation in the Galleria mellonella model. C18 might inhibit C. albicans via triggering mitochondrial dysfunction driven by ROS generation and Ca2 + accumulation.Original Research Paper  is about the evaluation of the antimicrobial efficiency of an ApoE mimetic peptide, COG1410, confirmed to exhibit strong neural protective activity and immunomodulatory function. COG1410 showed antimicrobial activity against pan drug-resistant Acinetobacter baumannii, even eliminating large inocula., COG1410 exhibited biofilm inhibition and eradication activity, stability in human plasma, and a low propensity to induce resistance. The mechanism of COG1410 killing was to disrupt the integrity of the cell. The strong synergistic interaction between COG1410 and polymyxin B dramatically reduced the working concentration of COG1410, expanding the safety window of the application in the C. elegans infection model and considered as a promising drug-candidate against pandrug-resistant A. baumannii.AF suggested the idea and conception of initiating that RT, drew the conclusions, wrote the first version of this editorial, which, however, it could not be materialized in the absence of the strong help of MB, who gave the most professional, formatting, and linguistic-grammar helps, and OM. OM proved an excellent editor of the published Research Articles and contributed with invaluable comments. All authors contributed to the article and approved the submitted version.The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher."}
{"text": "Retraction Note: Cellular Oncology (2020) 43:1017\u2013103310.1007/s13402-020-00553-1The Editors-in-chief have retracted this article because after publication concerns have been raised regarding a number of figures, specifically:Figure 3a: the 24h panels for m-NC and i-NC appear to be identical.Figure 4f: the AGS and BGC-823 panels for miR-4490/USP22 appear to partially overlap.The Editors-in-Chief therefore consider the data reported in this the article to be unreliable.Jide Wang does not agree to this retraction. The editor was not able to obtain a current email address for Tianming Chen. None of the other authors have responded to any correspondence regarding this retraction."}
{"text": "The authors wish to make a change to the published paper . In the The authors apologize for any inconvenience caused, and the change does not affect the scientific results. The manuscript will be updated."}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors\u2019 attention by a concerned reader that certain of the data showing cell invasion assay experiments in Figs. 2C, 4D and 5D were strikingly similar to data that had appeared in different form in other articles by different authors. Owing to the fact that the contentious data in the above article had already been published elsewhere, or were already under consideration for publication, prior to its submission to"}
{"text": "The Publisher retracts the cited article.Following publication, concerns were raised regarding the authorization and misinterpretation of some data used in this study. Specifically, during the investigation, which was conducted in accordance with Frontiers\u2019 policies, the authors failed to provide appropriate authorization for use of some of the original data. In addition, the Chief Editors of Frontiers in Oncology concluded that the article\u2019s conclusions were not sufficiently supported by the findings from the data provided. Given that unauthorized data use is a breach of Frontiers\u2019 guidelines, and that the Chief Editors expressed concern about the soundness of the conclusions, the article is being retracted.This retraction was approved by the Chief Editors of Frontiers in Oncology and the Chief Executive Editor of Frontiers. The authors and authors\u2019 institution agree to this retraction."}
{"text": "Phil. Trans. R. Soc. B376, 20200086. (Published 17 May 2021). (doi:10.1098/rstb.2020.0086)Some funding information was inadvertently omitted from the funding statement.This project has received funding from the European Union's Horizon 2020 research and innovation programme under the Marie Sk\u0142odowska-Curie grant agreement no. 841127."}
{"text": "Pseudomonas aeruginosa colonization of polymer microparticles and flat films\u2019 by Amanda H\u00fcsler et al., RSC Adv., 2018, 8, 15352\u201315357.Correction for \u2018Effect of surfactant on  The authors regret that the following information was not included in the original manuscript. All relevant data are available from the University of Nottingham\u2019s Research Data Management Repository under the DOI: 10.17639/nott.352, available at the following address: http://dx.doi.org/10.17639/nott.352The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Retraction Note: J Ovarian Res 15, 131 (2022)10.1186/s13048-022-01060-7The Editors-in-Chief have retracted this article. After publication, concerns were raised regarding the presented images and animal ethics. Specifically, in Fig. 2A, the images representing LV-shANGPTL4 #1 and #2 (24 h) appear to originate from the same sample (rotated 180\u00b0). In addition, the total tumour burden presented in Fig. 2D-G exceeds the recommended weight and volume limits for mouse xenograft experiments.The authors have stated that the same image was used in Fig. 2A by mistake, and that the weight and size of the tumours mentioned in this paper were the sum of the size of all miliary and rice-like tumors in the mouse peritoneal cavity, not the size of a single tumor. However, the total tumour size and weight exceeded the humane endpoints prescribed in the ethics approval for the study. Therefore, the Editors-in-Chief have decided to retract this article due to lack of adherence to the journal's expected ethical standards.All authors agree to this retraction."}
{"text": "Molecules. Details of the modifications are listed as follows to help readers to follow the updates:Due to the fact that the policy regarding the publication of images from the collection of the Papyrological Institute, the owner of the object under study, changed when the article was already in publication, the authors would like to make the following corrections to this paper  publisheIn the original publication, there was a figure  whose publication was not approved by the Papyrological Institute. Figure 1 has now been removed, and the following figures were renumbered accordingly.Gaia Federico\u201d. In the published publication, there was an error regarding the affiliation for \u201cThe original affiliation was: \u201cOpificio delle Pietre Dure, V. le Filippo Strozzi 1, 50129 Firenze, Italy; gaiafederico91@gmail.com\u201d.The correct afflicatioin should be \u201cOPD-Scuola di Alta Formazione e Studio, Via Alfani 78, 50121 Firenze, Italy; gaiafederico91@gmail.com\u201d. In the original publication, \u201cThe object analyzed in this study is currently under investigation at the G. Vitelli Papyrological Institute of Florence\u201d was not cited. The citation has now been inserted in the Acknowledgments, and should read:\u201cMarco Ciatti, conservators Patrizia Riitano, Lucia Bresci, and Licia Triolo from Opificio delle Pietre Dure, and Daniela Manetti and Francesca Maltomini from the G. Vitelli Papyrological Institute of Florence are gratefully acknowledged. The object analyzed in this study is currently under investigation at the G. Vitelli Papyrological Institute of Florence. Measurements discussed in the present paper were performed before the position of L. Liccioli within the IPERION HS project\u201d.The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. The original publication has also been updated."}
{"text": "The authors regret that an incorrect version of Fig. S1 was included in the original article. The correct version of Fig. S1 is presented below.trans-N,N-dimethyl carbamates in the peroxide-exposed, iron(ii)-reactive chair conformation using MarvinSketch (v19.10).Fig. S1 Representative conformations of putative bridged bicyclic trioxolane adducts, modelled as the The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "In the original publication , there wThe authors apologize for any inconvenience caused. The academic editor has checked this correction and state that the scientific conclusions are unaffected. The original publication has also been updated."}
{"text": "With great interest, we read the comment by Gilbert and Wicks on our recent publication  testing We fully agree with Gilbert et al. that the accuracy and usability of the Ada app is extremely user and use-case dependent. Whereas Ada\u2019s accuracy was extremely high (98%) in the rheumatoid arthritis vignette, it was clearly lower for the other two vignettes . In a recent publication  with actThe authors of the comment state that the app was designed for layperson users to test what underlying disease might be causing their health issues and state that the app explicitly is not developed for health care professionals (HCP). It is noteworthy that the underlying Ada intelligence is identical to Ada\u2019s HCP focused system. Remarkably, the same authors  publish"}
{"text": "The authors have not stated any conflicts of interest.In the Notes section (page 20), the conflicts of interest statement was missing. The following statement should be added:"}
{"text": "RSC Advances article due to concerns with the reliability of the data. The images in the article were screened by an image integrity expert. Images presented in this article have been duplicated in another publication by the authors.1The Royal Society of Chemistry hereby wholly retracts this Two of the kidney images (control group and model group) in Fig. 1 are identical to images presented in Fig. 2 of ref. Given the significance of the concerns about the validity of the data, the findings presented in this paper are not reliable.Qun Liang does not agree with the retraction. The other authors were informed but have not responded to any correspondence regarding the retraction.RSC AdvancesSigned: Laura Fisher, Executive Editor, th January 2021Date: 19"}
{"text": "Unfortunately all authors first and family names are published incorrectly. The correct names are below:Jodi OakmanSubas NeupaneSaila Kyr\u00f6nlahtiClas-H\u00e5kan Nyg\u00e5rdKatrina Lambert"}
{"text": "Assessment of humoral immunity and nutritionally essential trace elements in steady-state sickle cell disease Nigerian children before and after Prevenar 13 pneumococcal vaccination,\u201d published on pages 170-173, Issue 3, Volume 4 of Blood Science,1 the Ethical Consideration statement \u201cApproval for the study was obtained from the Health Research and Ethics Committee of the Lagos State University Teaching Hospital and the approval number is LREC/10/06/454.\u201d was omitted. The Journal and the authors wish to apologize for this error.In the article titled \u201c"}
{"text": "Two sections of the MI/R+Dex+EX527 panel of Figure 6b appear to be the same as sections in figure panel 2c of the Feng et al. paper, one of which is horizontally flipped. The authors have been contacted with regards to these concerns.The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an Expression of Concern to notify readers whilst the Editorial Office investigates. Duplications have been identified between this paper and another by Feng et al. 2017 (\u201cProtective effect of tanshinone IIA against cardiac hypertrophy in spontaneously hypertensive rats through inhibiting the Cys-C/Wnt signaling pathway\u201d DOI:"}
{"text": "In the Introduction, we better outlined our contributions with respect to our previous work, emphasizing that our main contribution concerns TTC estimation from aerial images.In the methodology Section 3.2, we shortened the last paragraph, removed Equation (1) and referred to our previous work [Figure 3 was reproduced from  to facilThe results in Table 1 were reproduced from experiments published in our previous work  (see TabThe authors wish to make the following corrections to the article . Parts oThe authors state that the scientific conclusions are unaffected. The original publication has also been updated."}
{"text": "The Publisher retracts the cited article.Following publication, the publisher uncovered evidence that false identities were used in the peer-review process. The assignment of a fake reviewer was confirmed by an investigation, conducted in accordance with Frontiers\u2019 policies and the Committee on Publication Ethics (COPE) guidelines.The investigation also uncovered concerns about the presentation and validity of the data in the article that normally would have led to a rejection. When contacted, the authors failed to provide a data set that adequately supports the reported conclusions.The authors do not agree to this retraction.This retraction was approved by the Chief Editors of Frontiers in Cell and Developmental Biology and the Chief Executive Editor of Frontiers."}
{"text": "During the course of a review of our publication, we found two errors in All co-authors agree with the content of this correction and we would like to apologize for any inconvenience caused to the readers by these changes."}
{"text": "There was an error in the original publication . In the A correction has been made in the abstract and in the result section (eighth paragraph): the number \u201c12\u201d was changed with \u201c8\u201d. The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "Computational and Mathematical Methods in Medicine has retracted the article titled \u201cDesign of Fuzzy Aided Cognition System for International Economic and Trade Information under Supply Chain Management\u201d [agement\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifiThe authors do not agree to the retraction."}
{"text": "Changes to \u201cauthors who contributed equally\u201dIn the original publication , the aut"}
{"text": "Bhattacharyya RSC Advances article following a misconduct investigation carried out by Gauhati University.The Royal Society of Chemistry hereby wholly retracts this There are repeating motifs within the AFM image in Fig. 7A. Gauhati University have informed us that they have concluded that the AFM image is devoid of authenticity and has been manipulated or altered by the authors.RSC AdvancesSigned: Andrew Shore, Executive Editor, th February 2019Date: 4"}
{"text": "Rosa canina fruit, and their use as recyclable and heterogeneous nanocatalysts for the degradation of dye pollutants in water\u2019 by Saba Hemmati et al., RSC Adv., 2018, 8, 22763\u201322763.Correction for \u2018Correction: Green synthesis of Pd nanoparticles supported on reduced graphene oxide, using the extract of  The affiliations in the original article were transposed; the corrected affiliations are as shown below.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Dear Editor:We wish to express appreciation to the authors for their kind words regarding our research article.P-values or confidence intervals. These two approaches always agree.2The authors raise the concern that in the data analysis subsection there are no details regarding the statistical methodology that is used to compare group differences. We feel that this is an incorrect statement. Proportions with 95% confidence intervals are an accepted and often recommended method of comparison between groups. We disagree that hypothesis testing, as suggested by the authors, is necessary as hypothesis testing and confidence intervals rely on the same underlying methodology. Statistical significance can be determined by P-values in medical research and considerable misuses and misconceptions regarding P-values. They also described the use of alternative methods that emphasize estimation over testing, such as confidence, prediction, or credibility intervals.P-values reported are the result of the two-sample z test for proportion, the only statistical test that we, as nonprofessional statisticians, are aware of for comparing proportions. This was requested by the journal editors to support our statements regarding statistically significant differences.In 2016, the American Statistical Association released a position paper describing the over reliance on P-value or statistical significance.The authors also cite a reference that describes ways to interpret a graph with error bars as it relates to confidence intervals and overlap in determining a Thank you for your comments and time on this important topic."}
{"text": "We regret that the original version of our paper unfortunately contained some inappropriate representative images. The immunostaining images of VASP in the LV-VASP and VASP-shRNA groups in Figure 2D, and the representative images of transwell in Figures 2B, 2C, and 4B were mis-pasted when choosing representative images from the large image data. The correct versions of Figures 2 and 4 appear below. The authors confirm that these corrections made in this erratum do not affect the original conclusions. All the authors of the paper have agreed to this correction. The authors apologize for any inconvenience that the errors may have caused."}
{"text": "The authors wish to make the following correction to this paper . In SectFull ethical clearance was obtained from the Malaysian National Medical Research Register Ethical Committee (NMRR-15-756-25320) and the Ethic Committee of the Faculty of Tropical Medicine, Mahidol University (MUTM 2016-028-01). All patients enrolled provided written informed consent prior to collection of sample specimens.Institutional Review Board Statement: The study was conducted in accordance with the Declaration of Helsinki and approved by the Malaysian National Medical Research Register Ethical Committee (NMRR-15-756-25320) and the Ethic Committee of the Faculty of Tropical Medicine, Mahidol University (MUTM 2016-028-01).The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "The authors wish to make the following corrections to the published paper . FiguresThe authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "Retraction Note to: Nanoscale Research Letters (2021) 16:27 10.1186/s11671-021-03475-5The Editors in Chief have retracted this article. After publication, concerns were raised concerning the appearance of Western blots. The authors did not respond to requests for further clarification and did not supply raw data or the ethics permit. The editors, therefore, have lost confidence in the integrity of the article\u2019s findings. The editor was not able to obtain a current email address for Author Yan Bao. Authors have not responded to any correspondence from the editor or publisher about this retraction."}
{"text": "Treatment of 1\u20133 with NaPF6 in methanol at RT affords quantitatively the corresponding derivatives [RuCl(PP)(tpy)]PF6 (PP=dppp (1\u2009a), \u2010Skewphos (2\u2009a) and \u2010Skewphos (3\u2009a)). Reaction of [RuCl2(PPh3)3] with \u2010Josiphos or (R)\u2010BINAP in toluene, followed by treatment with tpy in 1\u2010butanol and finally with NaPF6 in MeOH gives [RuCl(PP)(tpy)]PF6 \u2010Josiphos (4\u2009a), (R)\u2010BINAP (5\u2009a)) isolated in 78\u2009% and 86\u2009% yield, respectively. The chiral derivatives have been isolated as single stereoisomers and 3\u2009a, 4\u2009a have been characterized by single crystal X\u2010ray diffraction studies. The tpy complexes with NaOiPr display high photocatalytic activity in the transfer hydrogenation (TH) of carbonyl compounds using 2\u2010propanol as the only hydrogen donor and visible light at 30\u2009\u00b0C, at remarkably high S/C (up to 5000) and TOF values up to 264\u2005h\u22121. The chiral enantiomers 2, 2\u2009a and 3, 3\u2009a induce the asymmetric photocatalytic TH of acetophenone, affording (S)\u2010 and (R)\u20101\u2010phenylethanol with 51 and 52\u2009% ee, respectively, in a MeOH/2\u2010propanol mixture.The cationic achiral and chiral terpyridine diphosphine ruthenium complexes [RuCl(PP)(tpy)]Cl (PP=dppp ( 6) complexesThe new cationic ruthenium [RuCl(PP)(tpy)]X 3] a diphosphine and 2,2\u2032:6\u2032,2\u2032\u2032\u2010terpyridine (tpy), promote the photocatalytical transfer hydrogenation (TH) of carbonyl compounds in 2\u2010propanol under mild conditions. Unprecedented asymmetric catalytic TH of acetophenone driven by light was obtained with ruthenium tpy complexes containing the chiral Skewphos diphosphine. Highly efficient catalysts are the arene amino [RuCl(arene)(NN)]cis\u2010[RuCl2(ampy)(PP)]3)(CO)]n(tpy)(PPh3)3\u2212n]X2\u2212n2 Ruthenium complexes have been efficiently employed in C\u2212C and C\u2212H forming reactions via thermal homogenous catalysis. The transfer hydrogenation (TH)2\u2010based, semiconductors, nanoparticles and metal oxides systems,2(tpy)(biq)]  is found to promote the visible\u2010light\u2010driven TH of NAD(P)+ to NAD(P)H using HCO2Na in water.3]2+/viologen couple catalyzes the reduction of 2\u2010phenyl\u20102\u2010oxoethanoic acid using triethanolamine (TEOA) as a sacrificial donor,3]2+ photocatalytically affords hydrogen from TEOA.2Na in the absence of any additional photosensitizer, while [Cp*RhCl(bpy)]Cl3]X2 displaying a stereoinduced electron\u2010transfer process.It is worth noting that TH mediated by light has been reported using heterogeneous TiO6) from [RuCl2(PPh3)3], tpy and  diphosphines. These derivatives are efficient visible light\u2010induced ruthenium catalysts for the TH of carbonyl compounds using 2\u2010propanol. Asymmetric TH of acetophenone has been observed with the chiral tpy complexes. Ruthenium alkoxide and hydride species are also formed during catalysis under light irradiation.We report herein a straightforward preparation of cationic tpy ruthenium complexes of general formula [RuCl(PP)(tpy)]X 3] with dppp (1\u2005equiv.) in 1\u2010butanol at 90\u2009\u00b0C for 4\u2005h, followed by treatment with tpy at reflux for 12\u2005h affords the cationic ruthenium derivative [RuCl(dppp)(tpy)]Cl (1), isolated in 87\u2009% yield, via a [RuCl2(dppp)m(PPh3)n] intermediate  of 39.0\u2005Hz for the P atoms trans to Cl and N atoms, respectively. The H6/H6\u201d protons of the terminal pyridines give a doublet at \u03b4=7.80\u2005ppm =6.1\u2005Hz), upfield shifted compared to the free ligand (\u03b4=8.69\u2005ppm),13C{1H} NMR resonances of the C6/C6\u201d and C5/C5\u201d carbons are at \u03b4=156.7 and 126.3\u2005ppm, downfield shifted with respect to the free tpy , whereas the carbon atoms of the central pyridine are less deshielded . Treatment of 1 with NaPF6 in methanol (30\u2005min) affords [RuCl(dppp)(tpy)]PF6 (1\u2009a) as a red precipitate in 93\u2009% yield, by anion exchange 3] with an equimolar amount of \u2010Skewphos in 1\u2010butanol at 90\u2009\u00b0C for 4\u2005h, and subsequent reaction with tpy (1\u2005equiv.) at reflux for 12\u2005h, afforded the single stereoisomer [RuCl\u2010Skewphos)(tpy)]Cl (2) as a red product, isolated in 88\u2009% yield =38.5\u2005Hz) for the P atoms trans to Cl and N atoms, respectively, as established through the long range 4J coupling between the terminal ortho H6 and H6\u201d of tpy (at \u03b4H=8.83 and 6.63\u2005ppm) and the P trans to N . While the H6 resonance is slightly deshielded with respect to the free tpy, the H6\u201d signal is strongly upfield (\u0394\u03b4=2.06\u2005ppm), on account of the interaction with a phenyl of the Skewphos, showing a NOE with the ortho phenyl protons at \u03b4=6.29\u2005ppm . In addition, the CHCH3 moiety linked to the P trans to the chloride gives two signals at \u03b4=2.55 and 0.63\u2005ppm for CH and CH3 groups, while the resonances at \u03b4=3.78 and 1.44\u2005ppm are for the other CHCH3 unity, respectively. As for 1\u2009a, reaction of 2 with an excess of NaPF6 (2.5\u2005equiv.) in methanol at RT led to the complex [RuCl\u2010Skewphos)(tpy)]PF6 (2\u2009a) in quantitative yield. By using \u2010Skewphos, in place of \u2010Skewphos and following the same procedures for the synthesis of 2 and 2\u2009a, the corresponding enantiomers 3 and 3\u2009a have been isolated in 85 and 95\u2009% yield. The molecular structure of 3\u2009a has been confirmed by a single crystal X\u2010ray diffraction experiment, which allows to identify the stereochemistry at the ruthenium center \u2005\u00c5, which is shorter with respect to the terminal Ru1\u2010N1 and Ru1\u2010N2 lengths (2.107(2) and 2.148(2)\u2005\u00c5), as observed in [Ru(MeCN)(tpy)(dppbz)](PF6)2,3\u2009a in solution with one phenyl displaying high\u2010field shifted 1H NMR signals.The diphosphine complex S,R)\u2010Josiphos)(tpy)]PF6 (4\u2009a) and [RuCl((R)\u2010BINAP)(tpy)]PF6 (5\u2009a) have been obtained through a one\u2010pot reaction from [RuCl2(PPh3)3] and the corresponding chiral diphosphine, followed by treatment with tpy in 1\u2010butanol at reflux, giving the chloride complexes 4 and 5 which have been characterized in solution by NMR spectroscopy . Addition of NaPF6 allow the precipitation of 4\u2009a and 5\u2009a in pure form as single stereoisomers in 78 and 86\u2009% yield, respectively, =35.0\u2005Hz) and two very close doublets at \u03b4=40.6 and 39.5\u2005ppm =30.3\u2005Hz), respectively. For 4\u2009a, the terminal H6 pyridine proton is downfield shifted at \u03b4H=9.42\u2005ppm, whereas the corresponding H6\u201d is upfield at \u03b4H=6.41\u2005ppm due the anisotropic shielding of a diphosphine cyclohexyl rings showing a methylene proton upfield shifted at \u03b4H=\u22120.10\u2005ppm. The interaction of a cyclohexyl ring with the tpy has been evidenced also by the crystal structure of 4\u2009a, showing that the tpy plane is slightly tilted out of the equatorial plane due to the steric hindrance of a Cy group \u00b0 and 81.11(9)\u00b0, respectively, with a higher distortion with respect to 3\u2009a (91.14(7)\u00b0 and 86.44(7)\u00b0) and with a Ru1\u2212N2 distance of 2.009(3)\u2005\u00c5. Conversely, the mer\u2010RuCl(PP) arrangement has the expected geometrical features, with a Ru\u2212P2 distance of 2.3287(10)\u2005\u00c5 similar to that of 3\u2009a and the related [RuCl2\u2010Josiphos)(S)\u2010MePyme] derivative.5\u2009a are at \u03b4=9.43 and 6.23\u2005ppm, significantly shifted with respect to the free ligand , while the corresponding C6/C6\u2019 carbon atoms show \u0394\u03b4C values up to 11.0\u2005ppm compared to the free tpy, as inferred from COSY, NOESY and HSQC experiments.As a matter of fact the N2\u2212Ru1\u2212P2 and N2\u2212Ru1\u2212Cl1 angles in 1\u20133 and 2\u2009a\u20135\u2009a has been investigated in the TH of ketones and aldehydes to alcohols under light irradiation with a solar simulator (300\u2005W Xenon Arc Lamp). Interestingly, the tpy ruthenium derivatives are found active at remarkably high S/C up to 5000 with 2\u2010propanol as the only hydrogen donor and without the use of sacrificial reductants (e.g. triethanolamine) or photosensitizers , bearing the dppp diphosphine, catalyzes the TH of a (0.1\u2005M) in 2\u2010propanol with NaOiPr (2\u2005mol\u2009%) at 30\u2009\u00b0C, affording 94\u2009% conversion into 1\u2010phenylethanol in 16\u2005h and with TOF of 74\u2005h\u22121 (entry\u20051 of Table a (1\u2009%) is observed.Complex 2, bearing \u2010Skewphos, a complete reduction of a occurs in 8\u2005h, with TOF of 148\u2005h\u22121, affording the alcohol as racemic mixture (entry\u20052) and much of the same activity has been observed with 2\u2009a, indicating that the type of counterions (Cl\u2212 vs. PF6\u2212) does not affect the photocatalysis (entry\u20053). Interestingly, 2 catalyzes the TH of a at S/C=5000, with 86\u2009% conversion in 24\u2005h and high TOF=205\u2005h\u22121 (entry\u20054). A decrease of rate has been observed for different amounts of NaOiPr  (entries\u20055\u20137) with respect to 2\u2005mol\u2009%, whereas no photocatalysis occurs in the absence of the base.By using 2 promotes the photocatalytic TH of acetophenone (S/C=1000), affording (S)\u20101\u2010phenylethanol (89\u2009% conv) with 51\u2009% ee after 24\u2005h of irradiation, but with a lower rate  and a similar result has been obtained with 2\u2009a (entry\u20059). Using methanol as solvent, the same enantioselectivity has been achieved, but with only 6\u2009% conversion in 10\u2005h, due to the poor hydrogen donor capability of MeOH with respect to 2\u2010propanol.3 and 3\u2009a (S/C=1000) in 2\u2010propanol afford the TH of a in 10\u2005h , whereas in MeOH/iPrOH (1/1 in volume), 52\u2009% ee of (R)\u20101\u2010phenylethanol with 87\u2009% and 90\u2009% conv. is attained .Surprisingly, by using a 1/1 (v/v) mixture of 2\u2010propanol and MeOH, the complex ee values of the S and R alcohols are much the same, within the experimental error, and are consistent with the use of enantiomer catalysts. The derivatives 4\u2009a and 5\u2009a, bearing the diphosphine \u2010Josiphos and (R)\u2010BINAP, respectively, lead to 95 and 98\u2009% photocatalytic conversion of a in 14\u2005h with TOF=94 and 88\u2005h\u22121, respectively (entries\u200514 and 16), whereas using a MeOH/2\u2010propanol (1/1) mixture, leads to poor chiral induction . The comparison of the TH catalyzed by the pincer 4\u2009a in MeOH/2\u2010propanol (upon irradiation) with [RuCl(CNN)\u2010Josiphos)]S alcohol as predominant enantiomer. Conversely, 3 and 3\u2009a afford the R enantiomer, while the corresponding [RuCl(CNN)\u2010Skewphos)] derivativesS one. A mercury poisoning test2 shows the same performance, suggesting that the catalysis occurs in homogeneous phase (entry\u200518). It is worth pointing out that no decrease of the enantioselectivity or deactivation of the ruthenium catalyst has been observed during irradiation. To the best of our knowledge, this is the first example of an asymmetric TH of a ketone promoted by light. A solvent effect on the catalytic asymmetric hydrogenation of C=O and C=N bonds has been previously reported,3](PF6)2 has been shown to photocatalyze the TH of a leading to incomplete reduction (61\u2009% conv.) in 8\u2005h at 30\u2009\u00b0C and with a TOF of 73\u2005h\u22121 under the same catalytic conditions (entry\u200519).The 1 photocatalyzes the complete reduction of benzophenone b to benzhydrol at S/C=1000 after 12\u2005h of irradiation, with a TOF=115\u2005h\u22121 . Complex 1 catalyzes the TH of cyclohexanone c to cyclohexanol (91\u2009% conv.) at S/C=1000 in 18\u2005h , while with 2 at S/C=1000 and 5000, c is quantitatively reduced in 8 and 25\u2005h, respectively . The \u2010Josiphos derivative 4\u2009a affords 99\u2009% conversion of c in 21\u2005h at S/C=500 (entries\u20057). The aldehyde 4\u2010bromo\u2010benzaldehyde d is reduced with 1 (S/C=1000) to the corresponding alcohol (88\u2009% conv.) in 21\u2005h, whereas with 2 quantitative reduction occurs within a shorter time frame (18\u2005h) .To enlarge the scope of the photocatalytic TH, the NNN pincer complexes have been studied in the reduction of (bulky) ketones and aldehydes following the optimized protocol. Thus, 2CO3 (5\u2005mol%) as base leads to a lower rate, with 86\u2009% conversion in 18\u2005h (entry\u200510). Finally, the biomass derivative 5\u2010(hydroxymethyl)furfural (5\u2010HMF) e is efficiently reduced to 2,5\u2010bis(hydroxymethyl)furan (BHMF) (96\u2009% conv.) in 24\u2005h with 2 at S/C=1000 (entry\u200511).Employment of K3\u2009a in iPrOH/MeOH (1\u2009:\u20091) failed, while 4\u2010Me\u2010acetophenone affords 16\u2009% of R alcohol (4\u2009% ee) in 36\u2005h (Table\u2005S1). A diastereoselective reduction was observed with Cyrene (dihydrolevoglucosenone) leading to levoglucosanol with an erythro/threo ratio of 1\u2009:\u20091.7 (22\u2009% conv.). Finally, trans\u2010cinnamaldehyde has been reduced (31\u2009%) with low selectivity for the C=O vs. C=C bond (Table\u2005S1).Attempts to reduce 2\u2010Me\u2010acetophenone, 2\u2010MeO\u2010acetophenone with a to 1\u2010phenylethanol with 2 (S/C=5000) in 2\u2010propanol at 30\u2009\u00b0C increases linearly, while in the dark the alcohol is formed in tiny amount (<1%), resulting in a clear \u201con/off\u201d process and indicating that the pincer photocatalyst is active for days  follows a zero order kinetic till about 80\u2009% conversion and with complete formation of 1\u2010phenylethanol in 8\u2005h. Conversely, in the dark at 30\u2009\u00b0C the conversion is less than 2\u2009% while at refluxing conditions (82\u2009\u00b0C) only 11\u2009% of alcohol is formed in 8\u2005h , the reduction of h Figure\u2005.2 with NaOiPr (3\u2005equiv.) in 2\u2010propanol\u2010d8 at room temperature in the dark leads to a tiny amount of the ruthenium isopropoxide [Ru(OiPr)\u2010Skewphos)(tpy)](OiPr) (A) species . Upon irradiation (30\u2005min.) the complex A forms quantitatively through photo\u2010displacement of the chloride and has been characterized by NMR in solution =35.2\u2005Hz) for the P atoms trans to the O and N atoms, whereas the terminal tpy H6 and H6\u201d resonances are at \u03b4H=8.80 and 6.70\u2005ppm. In addition, the CH and CH3 signals of the RuOiPr moiety are at \u03b4H=3.93, 1.14\u2005ppm and \u03b4C=63.1 and 25.3\u2005ppm, respectively, as inferred from 1H\u201013C HSQC NMR measurements . After a longer irradiation period (>2\u2005h) the red\u2010orange solution of A turns dark brown, affording the ruthenium hydride [RuH\u2010Skewphos)(tpy)](OiPr) (B), through a light\u2010induced \u03b2\u2010hydrogen elimination with extrusion of acetone, in the presence of uncharacterized species =78.2 and 25.3\u2005Hz, for two P atoms trans and cis to the hydride, in agreement with the related CNN pincer ruthenium hydride complexes containing a diphosphine,\u03b4H = 8.30, 8.27, 8.11 and 7.86\u2005ppm for tpy ligand . NMR experiments performed in 2\u2010propanol/toluene\u2010d8 (1/1 in volume) as solvent leads to similar results, with formation of B in lower amount  and attempts to isolate the hydride B by treatment of 2 with NaOiPr in 2\u2010propanol failed. Reaction of the substrate b (1\u2005equiv.) with B in 2\u2010propanol/ toluene\u2010d8 (1/1 in volume), followed by irradiation for 1\u2005h, leads to the quantitative conversion to benzhydrol and acetone in the presence of B. Addition of a second equivalent of b give complete reduction after 1\u2005h under light, indicating that the hydride B is involved in the photocatalytic TH . Finally, irradiation of b with B in 2\u2010propanol\u2010d8 leads to partial deuteration of benzhydrol at the C\u03b1 position, via the formation of a RuD species .The alkoxide iPr derivative A, followed by a \u03b2\u2010H\u2010elimination of acetone, a process which is also induced by light (photo\u2010\u03b2\u2010H\u2010elimination), leading to ruthenium hydride B.C which is protonated by 2\u2010propanol with formation of the alcohol product and the isopropoxide A that closes the cycle (Scheme\u2005A) generally requires a cis vacant site,\u03b2\u2010hydrogen elimination in 18\u2010electron IrIII complexes through hydrogen bonding with the alcohol media has been claimed by Milstein.A undergoes a \u03b2\u2010hydrogen elimination and that the metal\u2010hydride B is involved in the ketone reduction, possibly through the formation of a Ru\u2010alkoxide, on account of the microscopic reversibility. The asymmetric TH of a with chiral pincer derivatives (2\u20105) in methanol/2\u2010propanol can be ascribed to the favorable chiral environment of the photocatalyst possibly by \u03c0\u2010stacking interaction of the aromatic rings. The asymmetric TH of acetophenone by pincer ruthenium complexes indicates that this process occurs through a well\u2010defined chiral photocatalyst without dissociation of the NNN and PP ligands. Therefore, this represents a rare example of visible light\u2010induced transition metal catalysis with ruthenium, which combines the catalyst\u2010substrate interaction with the photoinduced processes.Based on these results, it is likely that photocatalytic TH with the pincer complexes involves a light\u2010driven substitution of the chloride with formation of the Oe Scheme\u2005. It is w6) have been easily prepared in high yield through a one\u2010pot synthesis from [RuCl2(PPh3)3], a diphosphine, terpyridine (tpy) and additional NaPF6. By using the chiral diphosphines Skewphos, Josiphos and BINAP, single stereoisomers are formed. The reported tpy ruthenium complexes display high catalytic activity in the transfer hydrogenation (TH) of ketones and aldehydes to alcohols at 30\u2009\u00b0C induced by light irradiation, using 2\u2010propanol as the only hydrogen donor. These pincer complexes allow a remarkably high S/C up to 5000 and rate (TOFs up to 264\u2005h\u22121), while poor activity is found under thermal conditions. The chiral complexes [RuCl\u2010Skewphos)(tpy)]X (X=Cl and PF6) catalyze the TH of acetophenone in methanol/2\u2010propanol, affording (S)\u20101\u2010phenylethanol in 52\u2009% ee, while the enantiomers [RuCl\u2010Skewphos)(tpy)]X give the R alcohol. This is the first example of asymmetric catalytic TH of a ketone driven by light, indicating that this reaction occurs at a well\u2010defined and robust visible light\u2010induced ruthenium catalyst. For these tpy complexes, photo\u2010dissociation and photo\u2010\u00df\u2010H\u2010elimination reactions have been observed and are likely to occur during catalysis. Studies are ongoing to rationalize the mechanism of the photocatalytic reduction and to apply these catalysts in other C\u2212H activation reactions, including asymmetric transformations under light irradiation.In summary, the cationic terpyridine diphosphine ruthenium complexes [RuCl(diphosphine)(tpy)]X 3]1H and 13C{1H}, whereas H3PO4 was used for 31P{1H}. The atom\u2010numbering scheme for the NMR assignment of terpyridine ligand in the ruthenium complexes is presented in Figure\u2005R of acetophenone was 7.59\u2005min, while the tR of (R)\u2010 and (S)\u20101\u2010phenylethanol were 10.49\u2005min and 10.76\u2005min, respectively.Synthesis of [RuCl(dppp)(tpy)]Cl (1): [RuCl2(PPh3)3]  and dppp  were suspended in anhydrous 1\u2010butanol (5\u2005mL), and stirred at 90\u2009\u00b0C for 4\u2005h, until a light\u2010yellow precipitate of the PPh3\u2010diphosphine mixed species was formed.n\u2010pentane (2\u00d710\u2005mL) and dried under reduced pressure. Yield: 74\u2005mg (87\u2009%); 1H NMR : \u03b4=8.29 =8.1\u2005Hz, 2H; tpy ), 8.20 =8.4\u2005Hz, 4J=0.9\u2005Hz, 2H; tpy ), 8.05 =8.8\u2005Hz, 4J=1.3\u2005Hz, 4H; Ph), 7.98 =8.1\u2005Hz, 1H; tpy (H4\u2019)), 7.83 =7.7\u2005Hz, 4J=1.0\u2005Hz, 2H; tpy ), 7.80 =6.1\u2005Hz, 2H; tpy ), 7.54 =7.4\u2005Hz, 4J=1.3\u2005Hz, 2H; Ph), 7.46 =7.5\u2005Hz, 4J=1.8\u2005Hz, 4H; Ph), 7.24 =7.3\u2005Hz, 4J=1.2\u2005Hz, 2H; Ph), 7.08 =7.2\u2005Hz, 4J=5.6\u2005Hz, 5J=1.2\u2005Hz, 2H; tpy ), 6.96 =8.0\u2005Hz, 4J=2.1\u2005Hz, 4H; Ph), 6.58 =8.5\u2005Hz, 4J=7.3\u2005Hz, 5J=1.1\u2005Hz, 4H; Ph), 3.02 =8.2\u2005Hz, 2H; PCH2), 2.66\u20102.46 , 2.30\u2005ppm ; 13C{1H} NMR : \u03b4=158.9 =2.2\u2005Hz; ipso tpy ), 156.7 ), 155.0 ), 137.9 ), 137.4 ), 137.5\u2010128.2 , 126.3 ), 124.2 ), 122.9 ), 30.2 =26.0\u2005Hz, 3J=4.0\u2005Hz; PCH2), 23.7 =31.2\u2005Hz, 3J=4.0\u2005Hz; PCH2), 20.4\u2005ppm ; 31P{1H} NMR : \u03b4=34.1 =39.0\u2005Hz), 20.0\u2005ppm =39.0\u2005Hz); elemental analysis calcd (%) for C42H37Cl2N3P2Ru (817.70): C 61.69, H 4.56, N 5.14; found: C 61.75, H 4.60, N 5.20.6 (1\u2009a)Synthesis of [RuCl(dppp)(tpy)]PF: [RuCl(dppp)(tpy)]Cl  was dissolved in methanol (1\u2005mL), NaPF6  was added and the mixture was stirred at room temperature for 2\u2005h until a red precipitate was formed. The solid was filtered, washed with diethyl ether (2\u00d75\u2005mL), n\u2010pentane (2\u00d75\u2005mL) and dried under reduced pressure. Yield 74.2\u2005mg (93\u2009%); 1H NMR : \u03b4=8.12\u20107.97 ), tpy , Ph), 7.93 =8.0\u2005Hz, 2H; tpy ), 7.85 =7.8\u2005Hz, 1H; tpy (H4\u2019)), 7.82\u20107.78 ), 7.59\u20137.52 , 7.51\u20107.42 , 7.28 =7.4\u2005Hz, 2H; Ph), 7.15\u20107.04 ), 7.00 =8.0\u2005Hz, 4J=2.1\u2005Hz, 4H; Ph), 6.92\u20106.79 , 6.59 =8.8\u2005Hz, 4H; Ph), 2.97 =8.0\u2005Hz, 2H; PCH2), 2.68\u20102.46 , 2.23\u2005ppm ; 31P{1H} NMR : \u03b4=34.1 =39.1\u2005Hz), 19.6 =39.1\u2005Hz), \u2212144.4\u2005ppm =711.8\u2005Hz; PF6); elemental analysis calcd (%) for C42H37ClF6N3P3Ru (927.21): C 54.41, H 4.02, N 4.53; found: C 54.45, H 4.0, N 4.60.RSynthesis of [RuCl\u2010Skewphos)(tpy)]Cl (2): [RuCl2(PPh3)3]  and \u2010Skewphos  were suspended in anhydrous 1\u2010butanol (5\u2005mL) and stirred at 90\u2009\u00b0C for 4\u2005h, until an orange precipitate was formed. The ligand tpy  was added and the mixture was heated at reflux for 12\u2005h until a red solution was formed. The solvent was evaporated under reduced pressure, and the residue was dissolved in dichloromethane (1\u2005mL) and stirred at RT for 30\u2005min. Addition of diethyl ether (10\u2005mL) afforded the precipitation of the complex as a red solid that was filtered, washed with of diethyl ether (5\u00d710\u2005mL), n\u2010pentane (2\u00d710\u2005mL) and dried under reduced pressure. Yield: 77.5\u2005mg (88\u2009%); 1H NMR : \u03b4=8.83 =5.7\u2005Hz, 1H; tpy (H6)), 8.39 =7.1\u2005Hz, 4J=2.1\u2005Hz, 5J=1.1\u2005Hz, 1H; tpy (H3\u2019)), 8.14 =8.1\u2005Hz, 4J=1.5\u2005Hz, 1H; tpy (H3\u201d)), 8.06 =8.0\u2005Hz, 1H; Ph), 8.03\u20137.97  and (H3)), 7.97\u20107.91  and (H5\u2019)), 7.90\u20107.58 , 7.62 =7.7\u2005Hz, 4J=1.5\u2005Hz; tpy (H4\u201d)), 7.47 =7.7\u2005Hz, 4J=2.0\u2005Hz, 1H; Ph), 7.41\u20137.24 ), 7.16 , 7.08 =7.9\u2005Hz, 3J=2.1\u2005Hz, 2H; Ph), 6.99 =9.5\u2005Hz, 4J=8.2\u2005Hz, 5J=1.4\u2005Hz, 2H; Ph), 6.88 =8.1\u2005Hz, 4J=2.3\u2005Hz, 2H; Ph), 6.77 =7.4\u2005Hz, 4J=5.8\u2005Hz, 5J=1.5\u2005Hz, 1H; tpy (H5\u201d)), 6.63 =5.7\u2005Hz, 1H; tpy (H6\u201d)), 6.29 =8.6\u2005Hz, 4J=1.4\u2005Hz, 2H; Ph), 3.84\u20103.70 , 2.82 =15.0\u2005Hz, 3J=11.3\u2005Hz, 3J=3.7\u2005Hz; 1H; CHCH2), 2.61\u20132.49 , 2.27\u20132.04 , 1.44 =12.1\u2005Hz, 3J=7.5\u2005Hz, 3H; CHCH3), 0.63\u2005ppm =12.1\u2005Hz, 3J=6.8\u2005Hz, 3H; CHCH3); 13C{1H} NMR : \u03b4=158.9 =2.8\u2005Hz; tpy (C6)), 158.8 =2.2\u2005Hz; ipso tpy (C2)), 158.0 =2.6\u2005Hz; ipso tpy (C2\u2019)), 155.4 ), 155.1 ), 154.7 ), 141.8 =35.6\u2005Hz; ipso Ph), 137.8 ), 137.6 ), 137.2 ), 135.1\u2013126.9 , 126.2 ), 125.4 ), 124.6 ), 123.4 ), 123.0 ), 122.6 ), 37.3 =6.1\u2005Hz; CHCH2), 33.3 =22.2\u2005Hz; PCHCH3), 20.1 =27.6\u2005Hz, 3J=4.7\u2005Hz; PCHCH3), 19.0 =6.4\u2005Hz; PCHCH3), 18.0\u2005ppm ; 31P{1H} NMR : \u03b4=49.3 =38.5\u2005Hz), 33.9\u2005ppm =38.5\u2005Hz); elemental analysis calcd (%) for C44H41Cl2N3P2Ru (845.75): C 62.49, H 4.89, N 4.97; found: C 62.45, H 4.90, N 5.00.RSynthesis of [RuCl)\u2010Skewphos)(tpy)]PF: [RuCl\u2010Skewphos)(tpy)]Cl  was dissolved in methanol (0.5\u2005mL) and NaPF6  was added. The mixture was stirred at room temperature for 20\u2005min and the red precipitate was filtered, washed with diethyl ether (3\u00d75\u2005mL), n\u2010pentane (2\u00d75\u2005mL) and dried under reduced pressure. Yield 82.5\u2005mg (97\u2009%); 1H NMR : \u03b4=8.86 =5.7\u2005Hz, 4J=1.5\u2005Hz, 1H; tpy (H6)), 8.11\u20138.04 , (H3\u201d) and Ph), 7.96 =8.0\u2005Hz, 1H; Ph), 7.90 =7.8\u2005Hz, 4J=1.4\u2005Hz, 1H; tpy (H4\u2019)), 7.86\u20137.74 , (H3) and (H5\u2019)), 7.73\u20137.64 , 7.60 =7.7\u2005Hz, 4J=1.5\u2005Hz, 1H; tpy (H4\u201d)), 7.51\u20137.46 , 7.42\u20137.26 ), 7.09 =7.8\u2005Hz, 3J=2.2\u2005Hz, 2H; Ph), 7.00 =9.5\u2005Hz, 4J=8.2\u2005Hz, 5J=1.4\u2005Hz, 2H; Ph), 6.92\u20136.86 , 6.80 =7.5\u2005Hz, 4J=5.8\u2005Hz, 5J=1.5\u2005Hz, 1H; tpy (H5\u201d)), 6.66 =5.8\u2005Hz, 4J=1.6\u2005Hz, 1H; tpy (H6\u201d)), 6.29 =8.6\u2005Hz, 4J=1.3\u2005Hz, 2H; Ph), 3.86\u20133.70 ), 2.82 =15.1\u2005Hz, 3J=11.3\u2005Hz, 3J=3.6\u2005Hz; 1H; CHCH2), 2.60\u20132.49 , 2.28\u20132.04 , 1.44 =12.1\u2005Hz, 3J=7.5\u2005Hz, 3H; CHCH3), 0.64\u2005ppm =12.2\u2005Hz, 3J=6.8\u2005Hz, 3H; CHCH3); 31P{1H} NMR : \u03b4=49.0 =38.8\u2005Hz), 33.8 =38.8\u2005Hz), \u2212144.4\u2005ppm =711.4\u2005Hz; PF6); elemental analysis calcd (%) for C44H41ClF6N3P3Ru (955.27): C 55.32, H 4.33, N 4.40; found: C 55.30, H 4.30, N 4.45.SSynthesis of [RuCl\u2010Skewphos)(tpy)]Cl (3): Complex 3 was prepared following the procedure used for 2 employing \u2010Skewphos  in place of \u2010Skewphos. Yield: 75.0\u2005mg (85\u2009%). NMR data of 3 were identical to those of the enantiomer 2; elemental analysis calcd (%) for C44H41Cl2N3P2Ru (845.75): C 62.49, H 4.89, N 4.97; found: C 62.35, H 4.95, N 4.80.SSynthesis of [RuCl)\u2010Skewphos)(tpy)]PF: Complex 3\u2009a was prepared following the procedure used for 2\u2009a employing [RuCl\u2010Skewphos)(tpy)]Cl (3)  in place of [RuCl\u2010Skewphos)(tpy)]Cl (2). Yield 81.0\u2005mg (95\u2009%). NMR data of 3\u2009a were identical to those of the enantiomer 2\u2009a; elemental analysis calcd (%) for C44H41ClF6N3P3Ru (955.27): C 55.32, H 4.33, N 4.40; found: C 55.51, H 4.45, N 4.34.SSynthesis of [RuCl)\u2010Josiphos)(tpy)]PF: [RuCl2(PPh3)3]  and \u2010Josiphos  were suspended in anhydrous toluene (2\u2005mL) and stirred at 105\u2009\u00b0C for 4\u2005h. The dark\u2010red solution was cooled at room temperature and evaporated to dryness under reduced pressure. The residue was dissolved in anhydrous 1\u2010butanol (5\u2005mL), tpy  was added and the mixture was heated at reflux for 12\u2005h until a red solution was formed. The solvent was evaporated under reduced pressure and the residue was dissolved in dichloromethane (1\u2005mL) and stirred at RT for 30\u2005min. Addition of diethyl ether (10\u2005mL) afforded [RuCl\u2010Josiphos)(tpy)]Cl (4) as red\u2010brown precipitate that was filtered, washed with of diethyl ether (5\u00d710\u2005mL), n\u2010pentane (2\u00d710\u2005mL) and dried under reduced pressure. The product was dissolved in methanol (2\u2005mL) and NaPF6  was added. The mixture was stirred at RT for 30\u2005min and the red\u2010brown precipitate was filtered, washed with diethyl ether (3\u00d75\u2005mL), n\u2010pentane (2\u00d75\u2005mL) and dried under reduced pressure. Yield: 90.0\u2005mg (78\u2009%); 1H NMR : \u03b4=9.42 ), 8.52 =6.6\u2005Hz, 1H; tpy (H3\u2019)), 8.45 =8.4\u2005Hz, 1H; tpy (H3)), 8.30\u20138.21  and (H5\u2019)), 8.17 =7.9\u2005Hz, 1H; tpy (H4)), 8.11 =7.9\u2005Hz, 1H; tpy (H3\u201d)), 8.03 =8.8\u2005Hz, 2H; Ph), 7.76 =7.7\u2005Hz, 1H; tpy (H4\u201d)), 7.52\u20137.44 , 7.41\u20137.32 ), 7.20\u20137.06 , 6.72 =6.6\u2005Hz, 1H; tpy (H5\u201d)), 6.41 ), 5.14 , 4.87 , 4.81 =2.2\u2005Hz, 1H; C5H3), 3.81 , 3.45 , 2.02 =24.3\u2005Hz, 3J=11.5\u2005Hz, 1H; CH of Cy)), 1.63\u2013\u22120.18\u2005ppm  and CHCH3); 13C{1H} NMR : \u03b4=160.9 ), 160.0 ), 158.3 ), 157.1 ), 156.9 ), 154.5 ), 138.3 ), 137.9 , 137.6  and (C4\u201d)), 136.6\u2013126.9 , 126.0 ), 125.8 ), 123.8 ), 123.1 ), 122.3 ), 122.2 ), 98.6 , 75.9 , 70.7 , 70.5 , 70.0 =6.5\u2005Hz; C5H3), 37.7 =39.3\u2005Hz; CH of Cy), 37.3 =36.4\u2005Hz; CH of Cy), 30.8 , 29.4 =13.1\u2005Hz; CH2 of Cy), 27.9 =14.6\u2005Hz; CH2 of Cy), 27.4 =23.3\u2005Hz; PCHCH3), 27.2\u201326.8 , 26.6\u201326.2 , 25.8 , 15.4\u2005ppm =13.1\u2005Hz; PCHCH3); 31P{1H} NMR : \u03b4=47.6 =35.0\u2005Hz), 29.0 =35.0\u2005Hz), \u2212144.4\u2005ppm =710.0\u2005Hz; PF6).1H NMR : \u03b4=9.39 ), 8.82 =8.1\u2005Hz, 1H; tpy (H3\u2019)), 8.76 =8.2\u2005Hz, 4J=1.1\u2005Hz, 1H; tpy (H3)), 8.57 =8.0\u2005Hz, 1H; tpy (H5\u2019)), 8.42\u20138.34  and (H4)), 8.26 =7.5\u2005Hz, 1H tpy (H4\u2019)), 8.07 =8.7\u2005Hz, 2H; Ph), 7.86 =7.9\u2005Hz, 4J=1.2\u2005Hz, 1H; tpy (H4\u201d)), 7.53\u20137.43 ), 7.34 =6.9\u2005Hz, 2H: Ph), 7.31\u20137.24 , 7.22\u20137.15 , 7.11 =7.5\u2005Hz, 1H; Ph), 6.80 =6.8\u2005Hz, 1.0\u2005Hz, 1H; tpy (H5\u201d)), 6.45 ), 5.26 , 4.97 =2.7\u2005Hz, 1H; C5H3), 4.86 , 3.85 , 3.55\u20133.46 , 2.09 =24.1\u2005Hz, 3J=11.6\u2005Hz, 1H; CH of Cy)), 1.66\u2013\u22120.14 ; 13C{1H} NMR : \u03b4=161.2 ), 160.1 =4.8\u2005Hz; tpy (C6)), 158.7 ), 157.4 ), 157.2 ), 154.4 ), 138.6 ), 138.5 , 138.0 , 137.9 ), 137.8 ), 137.0\u2013126.4 , 126.1 ), 126.0 ), 124.0 ), 123.4 ), 122.9 =1.5\u2005Hz; tpy (C5\u2019)), 122.7 =1.7\u2005Hz; tpy (C3\u2019)), 95.1 =21.6\u2005Hz, 3J=3.4\u2005Hz; ipso\u2010C5H3), 76.0 , 70.6 =7.3\u2005Hz; C5H3), 70.4 , 69.7 =4.4\u2005Hz; C5H3), 37.5 =20.2\u2005Hz; CH of Cy), 37.3 =18.2\u2005Hz; CH of Cy), 30.7 , 29.2 =6.6\u2005Hz; CH2 of Cy), 27.6 =8.1\u2005Hz; CH2 of Cy), 27.5 =5.9\u2005Hz; PCHCH3), 27.0 , 26.7 =9.5\u2005Hz; CH2 of Cy), 26.5 =10.3\u2005Hz; CH2 of Cy), 26.4\u201326.0 , 25.6 , 14.6\u2005ppm =7.3\u2005Hz; PCHCH3); 31P{1H} NMR : \u03b4=49.2 =33.3\u2005Hz), 28.9 =33.3\u2005Hz), \u2212144.3\u2005ppm =708.8\u2005Hz; PF6); elemental analysis calcd (%) for C51H55ClF6FeN3P3Ru (1109.30): C 55.22, H 5.00, N 3.79; found: C 55.20, H 5.05, N 3.85.NMR data for compound 4: 1H NMR : \u03b4=9.37 ), 8.86 =7.9\u2005Hz, 1H; tpy (H3\u2019)), 8.80 =8.0\u2005Hz, 1H; tpy (H3)), 8.59 =7.9\u2005Hz, 1H; tpy (H4\u2019)), 8.41 =7.9\u2005Hz, 1H; tpy (H5\u2019)), 8.25  and (H3\u201d)), 8.05 =8.6\u2005Hz, 2H; Ph), 7.78 =8.2\u2005Hz, 1H; tpy (H4\u201d)), 7.56\u20137.22 ), 7.19\u20137.07 , 6.68 =6.7\u2005Hz, 1H; tpy (H5\u201d)), 6.38 ), 5.13 , 4.85 , 4.80 , 3.80 , 3.45 , 2.05 ), 1.68\u2013\u22120.20\u2005ppm  and CHCH3); 31P{1H} NMR : \u03b4=47.9 =34.4\u2005Hz), 29.2\u2005ppm =34.4\u2005Hz).R)\u2010BINAP)(tpy)]PF6 (5\u2009a)Synthesis of [RuCl((: [RuCl2(PPh3)3]  and (R)\u2010BINAP  were suspended in dichloromethane (10\u2005mL), and stirred at room temperature for 12\u2005h. The obtained orange solution was concentrated to almost 1\u2005mL by evaporation of the solvent under reduced pressure. Addition of diethyl ether (10\u2005mL) afforded the precipitation of [RuCl2((R)\u2010BINAP)(PPh3)]n\u2010pentane (2\u00d710\u2005mL) to remove the excess of the diphosphine. The solid was dissolved in anhydrous 1\u2010butanol (5\u2005mL), tpy  was added and the mixture was stirred at reflux for 12\u2005h until a red solution was formed. The solvent was evaporated under reduced pressure, the residue was dissolved in dichloromethane (1\u2005mL) and stirred at RT for 30\u2005min. Addition of diethyl ether (10\u2005mL) afforded [RuCl((R)\u2010BINAP)(tpy)]Cl (5) as orange\u2010red precipitate that was filtered, washed with diethyl ether (5\u00d710\u2005mL), n\u2010pentane (2\u00d710\u2005mL) and dried under reduced pressure. The product was dissolved in methanol (2\u2005mL), NaPF6  was added and the mixture was stirred at RT for 30\u2005min obtaining a red\u2010orange precipitate that was filtered, washed with diethyl ether (3\u00d75\u2005mL), n\u2010pentane (2\u00d75\u2005mL) and dried under reduced pressure. Yield: 101.7\u2005mg (86\u2009%); 1H NMR : \u03b4=9.43 =5.7\u2005Hz, 1H; tpy (H6)), 8.19 =8.1\u2005Hz, 4J=1.4\u2005Hz, 1H; naphthyl proton), 8.15 =8.1\u2005Hz, 4J=1.6\u2005Hz, 1H; tpy (H3)), 8.08 =7.8\u2005Hz, 4J=1.4\u2005Hz, 1H; tpy (H4)), 8.03\u20137.84 ), 7.76\u20137.60  and (H4\u201d)), 7.57\u20137.49  and aromatic proton), 7.48\u20137.43 ), 7.38 =7.4\u2005Hz, 1H; aromatic proton), 7.33\u20137.24 , 7.21\u20137.04 , 6.92\u20136.73 , 6.52\u20136.42 , 6.37\u20136.30 , 6.28\u20136.20 ), 6.08 =8.8\u2005Hz, 1H; Ph), 6.02\u2005ppm =8.6\u2005Hz, 2H; Ph); 13C{1H} NMR : \u03b4=160.5 ), 159.8 ), 159.6 ), 158.4 ), 156.7 ), 155.0 ), 138.8 ), 138.5 ), 137.0 ), 135.0\u2013125.9 , 126.8 , 125.7 ), 125.0 , 123.8 , 122.9 ), 122.4 ), 121.3\u2005ppm ); 31P{1H} NMR : \u03b4=40.6 =30.3\u2005Hz), 39.5 =30.3\u2005Hz), \u2212144.4\u2005ppm =709.7\u2005Hz; PF6); elemental analysis calcd (%) for C59H43ClF6N3P3Ru (1137.45): C 62.30, H 3.81, N 3.69; found: C 62.25, H 3.85, N 3.75.NMR data for compound 5: 1H NMR : \u03b4=9.35 =5.2\u2005Hz, 1H; tpy (H6)), 8.46 =7.9\u2005Hz, 1H; tpy (H3\u2019)), 8.40 =7.8\u2005Hz, 1H; tpy (H3)), 8.21 =8.6\u2005Hz, 2H; naphthyl protons), 8.11 =7.6\u2005Hz, 1H; tpy (H4)), 8.03\u20137.86 ), 7.85\u20137.76 , 7.76\u20137.65 , 7.63\u20137.52  and (H4\u201d)), 7.52\u20137.39  and aromatic proton), 7.33 =6.9\u2005Hz, 2H; aromatic protons), 7.31\u20137.20 ), 7.15\u20136.97 , 6.91\u20136.69 , 6.55\u20136.38 , 6.35\u20136.24 , 6.24\u20136.14 ), 6.07 =8.8\u2005Hz, 1H; Ph), 5.98\u2005ppm =8.5\u2005Hz, 2H; Ph); 31P{1H} NMR : \u03b4=40.8 =30.4\u2005Hz), 39.8\u2005ppm =30.4\u2005Hz).Typical procedure for the photocatalytic TH of aldehydes and ketones: The ruthenium catalyst solution used for the photocatalytic TH was prepared by dissolving the complexes (0.02\u2005mmol) in 2\u2010propanol (5\u2005mL). The catalyst solution  and a 0.1\u2005m solution of NaOiPr  in 2\u2010propanol were added subsequently to the carbonyl compound solution (1.0\u2005mmol) in 2\u2010propanol or a 2\u2010propanol/MeOH (1\u2009:\u20091 v/v) mixture . The resulting solutions were stirred in a thermostated water bath at 30\u2009\u00b0C. Irradiation of the samples was carried out by using a 300\u2005W Xenon Arc Lamp , emitting in the range 200\u20132500\u2005nm (solar simulator). Samples were purged with Ar at least 15\u2005minutes before irradiation. The reaction was sampled by removing an aliquot of the reaction mixture, which was quenched by addition of diethyl ether (1\u2009:\u20091 v/v), filtered over a short silica pad and submitted to GC analysis. The base addition was considered as the start time of the reaction. The S/C molar ratio was 1000/1, whereas the base concentration was 2\u2005mol% respect to the ketone substrates (0.1\u2005m). The same procedure was followed for TH reactions with other S/C (in the range 1000\u20135000) or with different base concentrations (1\u201310\u2005mol%), using the appropriate amount of catalysts, base and 2\u2010propanol.X\u2010ray crystallography: Single crystals of the complex 3\u2009a were obtained by slow cooling of a concentrated solution of the species in MeOH, whereas 4\u2009a crystallizes from CH2Cl2. X\u2010ray diffraction data were collected on a Bruker D8 Venture equipped with a CMOS detector (Photon\u2010100), a Mo TXS rotating anode (\u03bb=0.71073\u2005\u00c5), and a Helios optic monochromator (3\u2009a) and a Bruker D8 Venture equipped with a CPAD detector (Photon II), a Mo IMS microsource, and a Helios optic monochromator (4\u2009a). For additional details for collection and refining of data, see the Supporting Information.3\u2009a), 2165468 (for 4\u2009a)2165467  should be addressed to the authors.Supporting InformationClick here for additional data file."}
{"text": "There was a small error in the funder number of the first funder acknowledged and the correct version of the acknowledgements is shown below.The work was supported by the National Key R & D Program of China (No. 2016YFB0100400) and the National Natural Science Foundation of China .The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Bliss Independence model:On page 9 of (1), under the section \"Issue 6: combining more than two drugs\", the following error has been identified in the formula for the Combination Index for the Bliss Independence model in the case of a combination with more than two drugs is:The correct formula for the CI for the The authors apologize for the error."}
{"text": "Computational Intelligence and Neuroscience has retracted the article titled \u201cInhibitory Effect of Ursolic Acid on Proliferation and Migration of Renal Carcinoma Cells and Its Mechanism\u201d [chanism\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifi"}
{"text": "In the article titled \u201cInvestigation of Hepatoprotective Activity of Induced Pluripotent Stem Cells in the Mouse Model of Liver Injury\u201d , a dupliTo take into account the continuity of the hepatocyte differentiation from iPSCs to mature iPSC-derived hepatocytes, the authors have provided new images for Figures"}
{"text": "Social interactions transcending national contexts and individuals' cultural imprints are omnipresent in the contemporary world. This includes, but is not limited to, personal encounters, multi-ethnic teams in organizations, and not least, political conflicts. Beyond global business activities, developments of the last few years have added new dimensions to social cooperation and conflict across national borders. For example, fostered increase in digitized communication due to pandemic restrictions , or another community (Cologne), or a refugee who, in turn, can also be local or non-local. The authors' main finding is the (hypothesized) prevalence of ingroup bias . This work was supported by the Zentrum Digitalisierung.Bayern (ZD.B).The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher."}
{"text": "Vishwanathan et al., RSC Adv., 2018, 8, 11357\u201311366.Retraction of \u2018A highest stable cluster Au Springborg wishes to resign as co-author to the above article. Professor Springborg has declared that he was unaware of this submission, did not approve the manuscript and disagrees with some of its scientific conclusions.The corrected authorship list and affiliations for this paper are as follows:aK. Vishwanathan*a Physical and Theoretical Chemistry, University of Saarland, 66123 Saarbr\u00fccken, Germany. E-mail: vishwa_nathan_7@yahoo.com; Tel: +49-0151-63119680RSC Advances article due to unattributed text and equation overlap with a diploma thesis completed by Ingolf Warnke, under the supervision of Professor M. Springborg, at the University of Saarland in 2007 ((2) The Royal Society of Chemistry hereby wholly retracts this  in 2007 . There aRSC AdvancesSigned: Andrew Shore, Executive Editor, th December 2018Date: 4"}
{"text": "RSC Advances article due to concerns with the reliability of the data. Images published in Fig. 2 and 6 of the article have been duplicated in another article.1 There are no common authors between the papers.The Royal Society of Chemistry hereby wholly retracts this Rotated and scaled versions of the first and second tumor images in the \u2018sh-con\u2019 panel in Fig. 6B of this paper are duplicated in Fig. 5B of ref. A rotated version of the \u2018si-con/MCF-7\u2019 colony formation image in Fig. 2D of this paper is duplicated in Fig. 2E (\u2018si-con/SK-MEL-2\u2019 image) of ref. An inverted version of the \u2018si-PVT1#2/MDA-MB-231\u2019 colony formation image in Fig. 2D of this paper is duplicated in Fig. 2E (\u2018si-con/A375\u2019 image) of ref. The authors were asked to provide the raw data for this article, but did not respond. Given the significance of the concerns about the validity of the data, and the lack of raw data, the findings presented in this article are not reliable.The authors were informed but have not responded to any correspondence regarding the retraction.RSC AdvancesSigned: Laura Fisher, Executive Editor, Date: 18th August 2022"}
{"text": "As a result, ACJSNU launched an investigation and invited two independent referees to review the issues raised by PubPeer. Both referees agree that the paper displays signs of scientific fraud. In the meantime, ACJSNU requested that the corresponding authors of the paper provide the original experimental records and data for verification. However, the authors have failed to provide the requested documents and data to ACJSNU for examination. ACJSNU also noted that no surgeries are performed at the School of Life Science, College of Health Sciences, Jiangsu Normal University; it is unclear where the surgical specimens were obtained. Based on the investigation results, ACJSNU and the Editor-in-Chief believe that the paper has violated academic integrity and thus requested to retract this paper. Corresponding author Jun Lu disagrees with the retraction and stated that the data in question were obtained from a third party, which was not disclosed in the article.This article has been retracted at the request of the Editor-in-Chief and Academic Committee of Jiangsu Normal University (ACJSNU). ACJSNU informed the journal that in July 2020, ACJSNU became aware of PubPeer comments questioning Figures\u00a03B, 3C, and 6C ("}
{"text": "Computational and Mathematical Methods in Medicine has retracted the article titled \u201cLevetiracetam Attenuates the Spinal Cord Injury Induced by Acute Trauma via Suppressing the Expression of Perforin\u201d [erforin\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifi"}
{"text": "The Editors-in-Chief have retracted the article because the authors have been unable to provide documents confirming that ethics approval was obtained for the study. After publication the corresponding author requested a retraction but did not provide any further details. Upon further investigation it was identified that some of the described tumour sizes exceed 12\u00a0mm\u2014the maximum size allowed by the UK guidelines. The authors did not respond to any of the concerns raised.None of the authors have responded to any correspondence from the editor/publisher about this retraction."}
{"text": "In the original publication , there wArrows need to be added for tiny particles in (S5).The yellow arrow in (S2) is not in the correct position.(S3) and (S4) pictures need to be corrected.The corrected The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "The corrected Fig.After the publication of our article, we noted one error in Fig. Fig. ). Interestingly, higher IRF7 expression was inclined to predict a better prognosis in OS patients.\u201dAdditionally, the description of Fig. The authors confirm that the mistake does not affect the conclusions of the study and apologize for any inconvenience caused by this mistake."}
{"text": "Computational Intelligence and Neuroscience has retracted the article titled \u201cAntitumor Proliferation and Related Mechanism of Ultrasound Irradiation Combined with Safflower Yellow\u201d [ Yellow\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifi"}
{"text": "Equation (8) as published. Given the angle definition in the publication, \u201cEquation (8) should be \u201cEquation (8) is shown below.In the original publication , there wThe authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "The authors regret that there were errors in the Characterization of samples section of the original article, in Section 3.1 on page 720 of the original article. These errors are detailed below.4\u00b72H2O) are located at approximately 30.1\u00b0, 27.8\u00b0, 16.9\u00b0 and 10.9\u00b0\u2026\u201d should read, \u201cAs is known, the main peaks of CaHAsO4 are located at approximately 30.1\u00b0, 27.8\u00b0, 16.9\u00b0 and 10.9\u00b0, which can be indexed as the (221), (220), (101) and (020) lattice planes of CaHAsO4 (JCPDS no. 18-0288), respectively.\u201dThe sentence beginning, \u201cAs is known, the main peaks of scorodite (FeAsO3(AsO4)2 located at approximately 30.8\u00b0 and 31.7\u00b0, can be indexed as the (020) and (021) lattice planes of Ca3(AsO4)2 (JCPDS no. 01-0933).\u201dThe sentence beginning, \u201cAs is known, the main peaks of scorodite located at approximately 30.8\u00b0 and 31.7\u00b0\u2026\u201d should read, \u201cAs is known, the main peaks of CaThe Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "BioMed Research International has retracted the article titled \u201cFerroptosis-Related lncRNA for the Establishment of Novel Prognostic Signature and Therapeutic Response Prediction to Endometrial Carcinoma\u201d [rcinoma\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifiThe authors agree to the retraction."}
{"text": "After this article  was publSpecifically, the following data appear similar:Lanes 2 and 3 in the GAP-43 LAN-5 panel in Fig 1B.Lanes 2 and 3 in the IB:pTyr SH-SY5Y panel in Fig 2B.Lanes 2 and 3 in the IB:pTyr SK-N-BE panel in Fig 2B.Lanes 2 and 3 in the IB:pTyr LAN-5 panel in Fig 2B.Lanes 1 to 3 and lanes 4 to 6 in the IB:TrkB panel in Fig 2C.The right half of panel I and the left half of panel J in Fig 3.Lanes 2 and 3 in the pRet LAN-5 panel in Fig 4A.Lanes 2 and 4 in the Ret SH-SY5Y panel in Fig 4A.The 72h SH-SY5Y alpha tubulin panel and the 18h SK-N-BE alpha tubulin panel in Fig 5A.Lanes 2 and 3 in the Ret SK-N-BE panel in Fig 5B.Lanes 2 and 3 in the Ret LAN-5 panel in Fig 5B.PLOS ONE Editors consider that the underlying image provided for the 72h SH-SY5Y alpha tubulin panel of Fig 5A did not appear to match the blot shown in the published figure.In editorial follow up on these issues, underlying images from the original panels of concern were provided for Fig 5A. However, the The corresponding author stated that the remainder of the original data for the western blots presented in this article are no longer available. The corresponding author provided image data from replicate experiments in support of results reported in Figs 1B, 2B, 2C, 3, 4A and 5B, but these did not resolve the concerns about the published figures.PLOS ONE Editors retract this article.In light of the above issues, which could not be resolved in the absence of the original underlying data, the LC and CLE stand by the article\u2019s findings.LC and CLE disagreed with retraction. VdF and AD could not be reached."}
{"text": "Computational and Mathematical Methods in Medicine has retracted the article titled \u201cStudying the Effects of Cold Plasma Phosphorus Using Physiological and Digital Image Processing Techniques\u201d [hniques\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifiThe authors do not agree to the retraction."}
{"text": "Cell Death and Disease 10.1038/s41419-021-04103-x, published online 03 September 2021Retraction to: The authors have retracted this article. After publication the authors found that the staining done in Figure 5D had not been done with the antibody SOCS3 as stated in the article. The authors have, therefore, lost confidence in their results. All authors agree to this retraction."}
{"text": "Fusarium oxysporum f. sp. lactucae. The Fusarium oxysporum f. sp. lactucae is the scientific name of the studied fungus. Therefore, it must be written according to the scientific rules. Therefore, the style of this scientific name has to be corrected throughout the whole manuscript. The E-mail address of Mohamed S. Sedeek that was sent previously is now corrected to mohamed.sedeek@pharma.cu.edu.eg. The previous E-mail address used by Hanaa is now replaced by the official one hanaa.omar@agr.cu.edu.eg, as very recently required by Cairo University. This would positively reflect the actual citation record of our university accordingly. The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. The original publication has also been updated.The authors of this paper  have agr"}
{"text": "The authors wish to make a correction to the published version of their paper .Conflicts of Interest: The authors declare no conflict of interest.should beConflicts of Interest: M.K. is a shareholder-CEO in Wellnas Co., Ltd. K.N. is an inventor of pending (WO2015147251 and WO2018070545) and awarded (Japanese Patent No. 6192167 and Indonesia Patent No. P000063624) patents regarding this work and a shareholder in Wellnas Co., Ltd.We apologize for this error. The change does not affect the scientific results. The published version will be updated on the article webpage, with a reference to this correction notice."}
{"text": "Applied Bionics and Biomechanicshas retracted the article titled \u201cApplication of Internet of Things Artificial Intelligence and Knowledge Innovation System in Table Tennis Teaching and Training\u201d [raining\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifi"}
{"text": "Computational Intelligence and Neuroscience has retracted the article titled \u201cDesign of Financial Risk Control Model Based on Deep Learning Neural Network\u201d [Network\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifiThe authors agree to the retraction."}
{"text": "Publisher\u2019s Note: Predicting functional consequences of mutations using molecular interaction network features.The Publisher regrets that the article by Ozturk, K., Carter, H. (Ozturk and Carter We would like to express our thanks to the Guest Editors, Prof. Yana Bromberg and Prof. Predrag Radivojac, for their dedication and work assembling this collection of reviews and research for Human Genetics."}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors\u2019 attention by a concerned reader that certain of the data shown for the cell migration and invasion assays in Fig. 2C were strikingly similar to data appearing in different form in other articles by different authors. Owing to the fact that the contentious data in the above article had already been published elsewhere, or were already under consideration for publication, prior to its submission to"}
{"text": "The authors would like to make the following correction to the published paper .In the original publication, there was a mistake in Figure 1 as published. Figure 2 was reused, and Figure 1 was missed out by mistake during the revision process. The corrected 2.8. The Cellular Localization of AcJAZ Proteins\u201d.In the original publication, there was a mistake in the subtitle of 2.8. \u201cIdentification of JAZ Gene Family in Pineapple\u201d as published. The typo was introduced during the reordering of the subsections. The correct subtitle should be \u201cThe authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "Stem Cells Transl Med. 2022;11:461-477. https://doi.org/10.1093/stcltm/szac015This is a correction to: Servais S, Beguin Y, Baron F. Current status and perspectives of allogeneic hematopoietic stem cell transplantation in elderly patients with acute myeloid leukemia. In the originally published version of this article, the byline incorrectly showed the authors\u2019 surnames as first names. This error has been corrected to show first name followed by surname, as follows:Sophie Servais, Yves Beguin, Fr\u00e9d\u00e9ric Baron"}
{"text": "Furthermore, the authors apologize to the readership for any inconvenience caused.The authors have re-examined their original data, and have realized that these figures were assembled incorrectly; essentially, the si-AKT1-control data panel was selected incorrectly for"}
{"text": "Journal of Healthcare Engineering has retracted the article titled \u201cInfluence of Lower Extremity Deep Venous Thrombosis in Cerebral Infarction on Coagulation Index and Thromboelastogram and Its Risk Factors\u201d [Factors\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifi"}
{"text": "Computational Intelligence and Neuroscience has retracted the article titled \u201cCognitive Computation in Ideological and Political Classroom Teaching Based on Digital Sensor Technology\u201d [hnology\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifi"}
{"text": "Applied Bionics and Biomechanics has retracted the article titled \u201cAnalysis of Urban Residents' Consumption Behavior and Influencing Factors of Ecological Agricultural Products in the Post-Pandemic Era of COVID-19\u201d [Following an investigation conducted by the Hindawi Research Integrity team , signifiThe authors do not agree to the retraction."}
{"text": "The gastrointestinal tract (GI tract) is the tract of the digestive system that contains all the major organs of the digestive system. Disorder in any part of the GI tract results in various disease forms such as malignancies. The occurrence of GI cancer is very high in developed countries including Europe. A wide variety of natural products containing anticancer properties showed significant effects. Ginger, the rhizome of Zingiber officinale, is among one of the natural herbal remedies widely used for its spice and medicinal properties. It is fair sources of vitamins like, \u03b2-carotene, vitamin C and minerals. Recently ginger has shown significant attention in clinical studies due to its anti-cancer effects that possesses promising potential for inhibiting the proliferation of multiple cancer cells. The aim of this review is to provide a summarized report of clinical trials on ginger constituents and its effects on gastrointestinal malignancies. A systematic search was conducted by two independent authors on the databases of Scopus, Clinical Trials, PubMed and Science with the search term of the key words. This review article supported that ginger is an important plant with several constituents and gastrointestinal medicinal effects. Ginger constituents suppress the growth and induce apoptosis of variety of cancer types including colon, gastric, pancreatic and other GI cancers. It is mainly the 6-gingerol and 6-shogaol, of the major compounds in ginger rhizomes, among hundreds of molecules. It is reported that antioxidant and anti-inflammatory properties of ginger support its preventive role against the gastrointestinal malignancies.\u2022\u2002This review article provided evidences supporting the effects of ginger on gastrointestinal malignancies and demonstrates the importance of future studies.\u2022\u2002Therefore, more extensive and well-controlled clinical trial studies of ginger are required to demonstrate its effect on gastrointestinal malignancies."}
{"text": "The authors regret that some articles reporting probes for detecting human NAD(P)H:quinone oxidoreductase 1 were not cited in the original article. The missing references are listed below as 1\u20136Herein, we designed and synthesized a novel fluorescent probe 1 for detection of hNQO1 based on TCF-OH as a chromophore and quinone propionic acid (QPA) as a recognition group.The authors sincerely apologise for this oversight.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Authors Jaya Gill and Santosh Kesari have been added to the published article after they were mistakenly omitted from the original submission by the submitting author. The authors deeply regret this error."}
{"text": "The original version of this article unfortunately contained some mistakes.1. The authors found that the data unit in Fig.\u00a0The corrected version of Fig.\u00a02. The authors found that explanation of the data lines in Fig.\u00a02e is wrong.The corrected version of the explanation of Fig.\u00a02e is given below:The DNB can endure approximately 300% stretching and withstand stress up to about 1.5\u00a0MPa, as shown in Fig.\u00a02e."}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors\u2019 attention by a concerned reader that certain of the cell migration assay data shown in Fig. 2C were strikingly similar to data that had appeared in different form in other articles by different authors. Owing to the fact that the contentious data in the above article had already been published elsewhere, or were already under consideration for publication, prior to its submission to"}
{"text": "In the original publication , there wThe authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "Computational and Mathematical Methods in Medicine has retracted the article titled \u201cDiagnosis and Analysis of Transabdominal and Intracavitary Ultrasound in Gynecological Acute Abdomen\u201d [Abdomen\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifi"}
{"text": "Anesthesiology Research and Practice has retracted the article titled \u201cA Posterior TAP Block Provides More Effective Analgesia Than a Lateral TAP Block in Patients Undergoing Laparoscopic Gynecologic Surgery: A Retrospective Study\u201d [e Study\u201d . Since pThe authors and the editorial board approved this retraction."}
{"text": "Phil. Trans. R. Soc. B377, 2020045. (Published online 15 November 2021) (https://doi.org/10.1098/rstb.2020.0455)Phil. Trans. R. Soc. B377: 20200455 (Published online: 15 November 2021), it has been brought to the attention of the Editorial team that there are concerns regarding this study.Following the publication of \u2018Chimpanzee vowel-like sounds and voice quality suggest formant space expansion through the hominoid lineage\u2019 An investigation into these aspects is under way, and the journal is, therefore, issuing an expression of concern and will notify readers as to the results of our investigation as soon as possible."}
{"text": "Applied Bionics and Biomechanics has retracted the article titled \u201cDrop Height Impacts the Lower Limb Elastic Energy's Utilization for Male High Jumpers: A Experimental Research from Biomechanics\u201d [chanics\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifiThe authors do not agree to the retraction."}
{"text": "L in L promoter in the E7 open reading frame.In the published review , the HPVThe authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "Table 3 as published. In the chemical structure of ANT-3310  the NO bond was not clearly visible, and in the chemical structure of ANT-2681 , an amide functionality, was linked to the thiazole ring in place of an acid one. The corrected Structures of ANT-3310 and ANT-2681 appear below.In the original publication , there wANT-3310ANT-2681Scheme 16 as published. In the first three chemical structures of Scheme 16, a BnO ester functionality was reported in the place of an EtO one. The corrected Scheme 16 appears below.In the original publication, there was a mistake in Scheme 23 as published. In the final structure of ANT-2681, the PMB protecting group should not have been present. The corrected Scheme 23 appears below.In the original publication, there was a mistake in The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. The original publication has also been updated."}
{"text": "Retraction note: Mol Cancer 17, 155 (2018)https://doi.org/10.1186/s12943-018-0899-5Fig. 1b Exosomes/CytoD images appear to overlap with Fig. 6c Exosomes/PRO in [Fig. 1f UCP1 appear to be duplicated in Fig. 5d UCP1 in [Fig. 2a panel 2 appear to be duplicated in Fig. 1c panel 2 in [The Editor-in-Chief has retracted this article. After publication, concerns were raised regarding high similarity with the authors' other article that was under consideration within a similar time-frame . SpecifiIn addition, the western blots in Fig. 2C UCP3 (C2C12) and Fig. 3H UCP1 (Adipocytes) appear to originate from the same gel. The authors have provided the raw data to address these concerns; however, these data contained a number of further discrepancies. The Editor-in-Chief therefore no longer has confidence in the presented data.Qi Wu agrees to this retraction. None of the other authors have responded to any correspondence from the publisher about this retraction."}
{"text": "This has now been corrected online.The authors regret this error and apologize for any confusion that it has caused."}
{"text": "The Publisher retracts the cited article.Following publication, the publisher uncovered evidence that false identities were used in the peer-review process. The assignment of a fake reviewer was confirmed by an investigation, conducted in accordance with Frontiers\u2019 policies and the Committee on Publication Ethics (COPE) guidelines.The investigation also uncovered concerns about the presentation and validity of the data in the article that normally would have led to a rejection. When contacted, the authors failed to provide a satisfactory explanation.The authors do not agree to this retraction.This retraction was approved by the Chief Editors of Frontiers in Physiology and the Chief Executive Editor of Frontiers."}
{"text": "Following publication, concerns were raised regarding the validity of the data in the article. The authors failed to provide the raw data or a satisfactory explanation during the investigation, which was conducted in accordance with Frontiers\u2019 policies.Given the concerns, and the lack of raw data, the editors no longer have confidence in the findings presented in the article.The authors do not agree to this retraction.This retraction was approved by the Chief Editors of Frontiers in Cell and Developmental Biology and the Chief Executive Editor of Frontiers."}
{"text": "Retraction of: Hua Liu, Jing Cheng, Heng Xu and Zhenzhen Wan. Lidocaine has antitumor effect on hepatocellular carcinoma via the circ_DYNC1H1/miR-520a-3p/USP14 axis. Open Life Sciences. Volume 16, Issue 1, doi: 10.1515/biol-2021-0072.https://doi.org/10.1515/biol-2021-0072) has been retracted due to the previously undisclosed conflict of interest between the authors. Authors apologize to the entire scientific community and Editorial team for any issues ensuant from this action.\u201cLidocaine has antitumor effect on hepatocellular carcinoma via the circ_DYNC1H1/miR-520a-3p/USP14 axis\u201d ("}
{"text": "This article has been corrected with the consent of the authors to replace the term \"red man syndrome\" with \"vancomycin flushing syndrome\". In recent years, the term \"red man syndrome\" has fallen out of favor as it is now widely considered to be racist . The editorial office was alerted to this issue by a concerned reader, who we graciously thank for the insight. The authors are in full agreement regarding this change and together with the editorial office regret any harm caused by the use of the word."}
{"text": "RSC Advances article as there is insufficient data to support the structure of the final polymer product, and therefore, the conclusions are not fully supported. In Fig. 1 the peaks of the 1H-NMR spectrum are stacked together and therefore the spectrum cannot be used as proof of the polymer structure. In Fig. 2, the 13C-NMR spectrum, the peaks on the benzene ring cannot correspond to before and after polymerization. Therefore, further research and characterization work is needed to determine the structure of the resulting polymer.We, the named authors, hereby wholly retract this The corresponding authors regret this oversight and apologise for any inconvenience to readers.\u00a0Signed: Lichao Dong, Tian Lan, Yin Liang, Shifeng Guo and Hao ZhangDate: 18 April 2021\u00a0RSC AdvancesRetraction endorsed by Laura Fisher, Executive Editor,"}
{"text": "In the original publication, there was a mistake in Table 2 as published . There wThe authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. The original publication has also been updated."}
{"text": "In"}
{"text": "We witness the increasing use of artificial intelligence (AI) in science, and the recent release of the ChatGPT chatbot has brought generative AI into publishing.A chatbot is defined as \u201ca computer program that simulates and processes human conversation (either written or spoken), allowing humans to interact with digital devices as if they were communicating with a real person\u201d .Journal of Global Health adopts the recommendations from the World Association of Medical Editors (WAME) to update our policy on authorship [Since the introduction of ChatGPT by OpenAI in November 2022 [thorship :1. Chatbots cannot be authors.Chatbots cannot meet the requirements for authorship as they cannot understand the role of authors or take responsibility for the paper. Chatbots cannot meet the authorship criteria of the International Committee of Medical Journal Editors (ICMJE) , particu2. Authors should be transparent when chatbots are used and provide information about how they were used.Since the field is evolving quickly at present, authors using a chatbot to help them write a paper should declare this fact and provide full technical specifications of the chatbot used  and method of application in the paper they are submitting . This is consistent with the ICMJE recommendation of acknowledging writing assistance .3. Authors are responsible for the work performed by a chatbot in their paper  and for appropriate attribution of all sources .Human authors of articles written with the help of a chatbot are responsible for the contributions made by chatbots, including their accuracy. They must be able to assert that there is no plagiarism in their paper, including in text produced by the chatbot. Human authors must ensure there is appropriate attribution of all quoted material, including full citations. They should declare the specific query function used with the chatbot. Authors will need to seek and cite the sources that support the chatbot\u2019s statements. Since a chatbot may be designed to omit sources that oppose viewpoints expressed in its output, it is the authors\u2019 duty to find, review and include such counterviews in their articles.In line with the 4th WAME recommendation , we willJournal of Global Health. After full twelve great years of working with outstanding experts in global health and working with you on creating the journal, I am ready to take new challenges, just as we all face new challenges in scientific publishing.I would like to use this opportunity to inform our readers that I will be stepping down as the Co-editor in Chief of the"}
{"text": "Scientific Reports 10.1038/s41598-017-00306-5, published online 15 March 2017Retraction of: Ponceau S staining images in Fig.\u00a02a and bPonceau S staining images in Fig.\u00a02 between lanes 1\u20133 and lanes 4\u20136Western blots presented for Actin in Fig.\u00a03b and Porin in 3cThe Editors have retracted this Article. After publication, concerns were raised regarding high similarity in images used in the figures presented in this Article. Specifically:The Editors therefore no longer have confidence in the presented data.Nader G. Abraham agrees to this retraction. Komal Sodhi, Rebecca Martin, Preeya T. Shah, Muhammad Chaudhry, Jiang Liu, and Joseph I. Shapiro do not agree to this retraction. Krithika Srikanthan, Perrine Goguet-Rubio, Alexandra Nichols, Amrita Mallick, Athar Nawab, Saroj Sigdel, Mehiar El-Hamdani, and Zijian Xie have not responded to any correspondence from the Editors about this retraction."}
{"text": "Computational Intelligence and Neuroscience has retracted the article titled \u201cPackaging Big Data Visualization Based on Computational Intelligence Information Design\u201d [ Design\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifi"}
{"text": "This abstract has been withdrawn."}
{"text": "There was an error in the original publication .In the original article, an incorrect IACUC protocol number was inadvertently included, and the article should have referenced protocol 19-016. All reported animal experiments and procedures were conducted in accordance with the guidelines established and approved by Beltsville Area Animal Care and Use Committee under protocol 19-016.A correction has been made under Materials and Methods Section Under 2.1 Animals and Diets: all animal experiments and procedures were conducted in accordance with the guidelines established and approved by Beltsville Area Animal Care and Use Committee under protocol 19-016.A correction has been made under Institutional Review Board Statement: all animal experiments and procedures were conducted in accordance with the guidelines established and approved by Beltsville Area Animal Care and Use Committee under protocol 19-016.The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors\u2019 attention by a concerned reader that cell migration assay data shown in Figs. 2C and 5D were strikingly similar to data that had appeared in different form in other articles by different authors. Owing to the fact that the contentious data in the above article had already been published elsewhere prior to its submission to"}
{"text": "Applied Bionics and Biomechanics has retracted the article titled \u201cData Mining and Analysis of Management Theory on the Emotional Recognition of Students' Physical Fitness Improvement\u201d [ovement\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifiThe authors do not agree to the retraction."}
{"text": "Computational and Mathematical Methods in Medicine has retracted the article titled \u201cComplexity Assessment of Chronic Pain in Elderly Knee Osteoarthritis Based on Neuroimaging Recognition Techniques\u201d [hniques\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifi"}
{"text": "The authors wish to make the following corrections to this paper :There are mistakes regarding the possibility for growth on several substrates shown in The correct version is as follows:The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. The original publication has also been updated."}
{"text": "We regret that the original version of our paper unfortunately contained one incorrect representative image. The wrong image was placed in the miR-376c-3p inhibitors + NT siRNA group in Figure"}
{"text": "Sookhakianc has been published in RSC Advances.The following article \u2018Crystalline quality assessment, photocurrent response and optical properties of reduced graphene oxide uniformly decorated zinc oxide nanoparticles based on the graphene oxide concentration\u2019 by Majid Azarang*RSC Advances is publishing this expression of concern in order to alert our readers to the fact that we are presently unable to confirm the accuracy of the data reported in Fig. 10, 16, and 18 and Table 4 of this RSC Advances paper.We have contacted the University of Malaya to request an investigation into the validity of the published findings. We understand that an investigative process is on-going at the University of Malaya, and this notice will be updated when a final outcome is reached.Andrew Shore2nd March 2018RSC AdvancesExecutive Editor,"}
{"text": "In the sentence beginning \u201cA C-shaped \u2026.\u201d in this article, the text \u201cin 3R tau and G304-E380 in 4R tau\u201d is mistakenly added. The correct sentence should read as \u201cA C-shaped core structure consisting of V306-F378 was identified in the brain of one individual with AD.\u201d"}
{"text": "PMID: 35892078; PMCID: PMC9281584, authors requested to change the order of the co-authors, making Dr Tianye Lin as the first author. As a result of that the correct order of the authors is as follows:In the published article Zhang Z, Lin T, Zhong Y, Song W, Yang P, Wang D, Yang F, Zhang Q, Wei Q, He W. Effect of femoral head necrosis cystic area on femoral head collapse and stress distribution in femoral head: A clinical and finite element study. Open Med. (Wars) 2022 Jul 13;17(1):1282\u201391. doi: Tianye Lin, Zhaoming Zhang, Yuan Zhong, Wenting Song, Peng Yang, Ding Wang, Fan Yang, Qingwen Zhang, Qiushi Wei and Wei He."}
{"text": "Methods, 2022, 14, 2732\u20132738, https://doi.org/10.1039/D2AY00604A.Correction for \u2018Novel  In the original article, in the sentence in the introduction beginning \u201cPrevious studies have reported LODs of <1 Bq\u2026\u201d, the number of atoms approximately equal to 1 Bq was incorrect. The corrected sentence is given below.9 atoms) by ICP-MS/MS,8,9 4 mBq by RIMS,11 and <1 mBq by TIMS.12,13Previous studies have reported LODs of <1 Bq (1 Bq \u2248 1.3 \u00d7 10The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Cell Death Discovery 10.1038/s41420-021-00722-7, published online 30 October 2021Correction to: Cell Death Discovery for giving our opportunity to publish the Corrigendum, and all the authors agreed with this correction. The authors apologized for any inconvenience caused by this error.Since the online publication of this article, the authors have noticed that there was an error in Fig. 2D, which arose during the assembly of the figure; specifically, the upper-left picture in Fig. 2D, showing the result of the \u201ccontrol of migration for MCF7\u201d was mistakenly used. The revised version of Fig. 2D including the corrected data for \u201ccontrol of migration for MCF7\u201d, was shown in the below, and the new bar graph was also provided. The authors confirmed that this mistake did not influence the data, discussion, or conclusions of this study. And we are grateful to the Editor of"}
{"text": "Bioscience Reports at the request of the authors following receipt of a notification from a reader, alerting the Editorial Office to two regions of the figure 6b MI/R + Dex + EX527 panel that also appear in another paper by different authors  doi: 10.18632/oncotarget.14328). The Editorial Office also has concerns regarding the western blot images. The authors wish to retract the article, and the Editor-in-Chief and Editorial Board agree with the retraction.This Retraction follows an Expression of Concern relating to this article previously published by Portland Press. This article is being retracted from"}
{"text": "Following the publication of this article , concern\u25cb Fig 6 AIF panel, lanes 1 and 3, and Fig 8 right OGG1 panel, lane 2.\u25cb Fig 6 AIF panel, lane 2, and Fig 8 right OGG1 panel, lanes 1 and 3.\u25cb Fig 6 left \u03b2-actin panel, lanes 1, 2, 3 and 4.\u25cb Fig 9A far left GAPDH panel, all lanes, and Fig 9A MtTFB1 panel lane 2.The following bands appear similar:\u25cb Fig 6 Cytochrome-C panel between all lanes.\u25cb Fig 8 right OGG1 panel, between lanes 1\u20132, and lanes 3\u20134.\u25cb Fig 8 left OGG1 panel, between lanes 1\u20132, and lanes 3\u20134.\u25cb Fig 9A middle left GAPDH panel, between lanes 3\u20134.\u25cb Fig 9A middle right GAPDH panel, between all lanes.\u25cb Fig 9A POLRMT panel, between lanes 3\u20134.\u25cb Fig 9A far right GAPDH panel, between lanes 1\u20132 and lanes 2\u20133.\u25cb Fig 9B MtTFA panel, between lanes 2\u20133.\u25cb Fig 9B far left \u03b2-actin panel between lanes 3\u20134.\u25cb Fig 9B MtTFB1 panel and corresponding \u03b2-actin panel, between lanes 2\u20133.\u25cb Fig 9B far right \u03b2-actin panel between lanes 2\u20133 and lanes 3\u20134.When levels are adjusted to visualize background, there appear to be vertical irregularities suggestive of splice lines in:The corresponding author stated that some images were spliced during figure preparation to remove extra lanes and/or replicates. They commented that data files were provided to PLOS in 2014\u20132015, but the underlying data for the figures of concern are no longer available in the laboratory records. PLOS is unable to access the journal\u2019s 2014 correspondence records for this case. We sincerely regret that this case was not resolved much sooner after the prior correspondence.PLOS ONE Editors retract this article. Although we have been unable to review the primary data, the nature and extent of image concerns call into question the integrity of data reporting in the published figures and the reliability of the article\u2019s results and conclusions.The GM, FB, and FPG agreed with the retraction and apologise for the issues with the published article. JFB, ED, and EL did not agree with the retraction. RT, DM, and DA either did not respond directly or could not be reached. ES is deceased."}
{"text": "The section should read as follows:In the subsection SNR: LGN Populations within the Methods, the three equations immediately following Eq 11 should not have a superscript wT\u03bc, and the net noise was The net signal was therefore Signal and noise were pooled across two identical and weakly anticorrelated (r = \u22120.05 [87]) mosaics of neurons  and from a second, independent eye. The final scale factor was therefore"}
{"text": "The Publisher retracts the cited article.Following publication, the publisher uncovered evidence that false identities were used in the peer-review process. The assignment of a fake reviewer was confirmed by an investigation, conducted in accordance with Frontiers\u2019 policies and the Committee on Publication Ethics (COPE) guidelines.The investigation also uncovered concerns about the presentation and validity of the data in the article that normally would have led to a rejection. When contacted, the authors failed to provide a data set that adequately supports the reported conclusions.The authors do not agree to this retraction.This retraction was approved by the Chief Editors of Frontiers in Physiology and the Chief Executive Editor of Frontiers."}
{"text": "The authors regret that the author list was shown incorrectly in the original article. The correct author list is as shown below:a, Archana Kanwade\u2020a, Akash Kankanea, Manish Kumar Tiwaria, Abhishek Srivastavaa, Jena Akash Kumar Satrughnab, Subhash Chand Yadava and Parasharam M. Shirage*aSheetal Gupta\u2020aDepartment of Metallurgy Engineering and Materials Science, Indian Institute of Technology, Indore 453552, India, E-mail: pmshirage@iiti.ac.in, paras.shirage@gmail.combDepartment of Physics, Indian Institute of Technology, Indore 453552, India\u2020 Equal contributions.Additionally, the authors regret that the photos of Ms Archana Kanwade and Ms Sheetal Gupta are incorrectly displayed. The correct photos are shown below:(1) The photo of Ms Sheetal Gupta is as follows:(2) The photo of Ms Archana Kanwade is as follows:The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "This Retraction follows an Expression of Concern relating to this article previously published by Portland Press.Bioscience Reports at the request of the Editor-in-Chief and the Editorial Board following receipt of a notification from a reader, alerting the Editorial Board to repeated images in Figure 5.This article is being retracted from The Editorial Office was also contacted by the listed corresponding author, Derong Ma, via an email address that differed to the one included with the submission. Derong Ma confirmed that they were unaware of the submission and publication of the article, and that they did not conduct any part of this research, hence should not have been listed as an author on this paper.The corresponding author of the paper has been contacted via the original email address in the published paper to provide a response to the Editorial Office concerns surrounding the authorship of the paper but has not responded.In light of the concerns raised regarding the Western blots and the authorship of the paper, the Editorial Board stands by the decision to retract the paper."}
{"text": "Signal Transduction and Targeted Therapy 10.1038/s41392-021-00867-y, published online 18 February 2022Correction to: 1. The correct data are provided as follows. The key findings of the article are not affected by these corrections. The original article has been corrected.Staining labels in Fig. 4b were mislabeled as \u201cNeuN\u201d (Green) and \u201cC1q\u201d (Red), which should be \u201cNeuN\u201d (Red) and \u201cC1q\u201d (Green) as shown below.Fig. 4b Representative images of C1q stained with NeuN in the CA3 region of 6-week-old MRL/mpj and MRL/lpr mice.The middle and bottom panels of Fig. 6g that showed the fluorescence images of PSD-95 and F-actin/PSD-95 co-location in the mouse hippocampal sections were wrongly inserted. The correct results should be as shown below.In the process of collating the raw data, the authors noticed two inadvertent mistakes occurred in Fig. 4b and Fig. 6g (and the corresponding uncropped images in \u201cSupplementary Data Fig. 6g Representative images of F-actin and PSD-95 in the hippocampal CA3 region.Supplementary Data 2 - Updated"}
{"text": "H = DSz2 \u2212 \u03b3NV(Sx(BAx + Bx) + Sy(BAy + By) + Sz(BAz + Bz))\u201d. It should read \u201cH = DSz2 \u2212 \u03b3NV(Sx(BAx + Bx) + Sy(BAy + By) + Sz(BAz + Bz))\u201d. On line 7 in the left column on page 180 of the original article, the text originally read \u201cBmin \u2245 4 \u0393 (33 \u03b3NV \u00d7 C)\u22121 (I0 \u00d7 t)\u22121\u201d. It should read \u201cBmin \u2245 4 \u0393 (3\u221a3 \u03b3NV \u00d7 C)\u22121 (I0 \u00d7 t)\u22121/2\u201d. On line 23 in the left column on page 180 of the original article, the text originally read \u201cS = Fl(f1) \u2212 Fl(f2))/(Fl(f1) + Fl(f2)\u201d. It should read \u201cS = (Fl(f1) \u2212 Fl(f2))/(Fl(f1) + Fl(f2))\u201d.The authors regret that there were errors that appear in the Results and discussion section. On line 47 in the right column on page 179, the text originally read \u201cThe authors regret that there was an error in the text in the Author contributions section on line 24 in the right column on page 183 of the original article. The text originally read \u201cASQ\u201d. It should read \u201cSQAS\u201d.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "The journal retracts the\u00a012 February 2019 article cited above.Following publication, concerns were raised regarding the integrity of the data in the published figures. The authors failed to provide a satisfactory explanation during the investigation, which was conducted in accordance with Frontiers\u2019 policies.This retraction was approved by the Chief Editors of Frontiers in Immunology and the Chief Executive Editor of Frontiers. The authors do not agree to this\u00a0retraction."}
{"text": "The revised version of"}
{"text": "Journal of Healthcare Engineering has retracted the article titled \u201cValue Analysis of Using Urinary Microalbumin in Artificial Intelligence Medical Institutions to Detect Early Renal Damage in Diabetes\u201d [iabetes\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifi"}
{"text": "In"}
{"text": "Dear Editor2 on the importance of a thorough assessment of the problem and the recognition of probable vaccination\u2010induced diabetes. On the other hand, we would like to add a note about another possible concurrent issue that could cause DKA in a vaccine recipient.We would like to share ideas on the publication \u201cDiabetic ketoacidosis shortly after COVID\u201019 vaccination in a non\u2010small \u2010cell lung cancer patient receiving combination of PD\u20101 and CTLA\u20104 inhibitors: A case reportThe authors confirm that there are no conflicts of interest."}
{"text": "After much investigation, we realized that there is a flaw in The TEM and the cellular microscopy images werewrongly placedin"}
{"text": "Adv. Sci. 2019, 6, 180080810.1002/advs.201800808DOI: In Vivo Studies\u2014Fiber\u2010Hydrogel Scaffold Fabrication\u2019 15 \u00b5l of 100 \u00d7 10\u22123m of miR stock, instead of 7.5 \u00b5l, was added to achieve a total mass of 20 \u00b5g miR loaded into the collagen mixture. This typo error was spotted after revisiting the calculations. We confirmed that the absolute mass of miR received by each animal and the absolute mass of miR added into the collagen mixture, as stated in the original paper, are both correct. The authors apologize for any inconvenience this may have caused.In the original published article, in the Methods subsection \u2018"}
{"text": "Scientific Reports 10.1038/s41598-020-80075-w, published online 08 January 2021Correction to: This Article contained an error in the ethical approval statement.Animals and groupings,The text in the Materials and Methods, under the subheading \u201cThe study design strictly adhered to the guidelines approved by Institutional Animal Care and Use Committee (IACUC) of our institute, Institute of Nuclear Medicine and Allied Sciences (INMAS), Defence Research and Development Organization (DRDO), Delhi, India \u201dnow reads\u201cThe study design strictly adhered to the guidelines approved by Institutional Animal Care and Use Committee (IACUC) of our institute, Institute of Nuclear Medicine and Allied Sciences (INMAS), Defence Research and Development Organization (DRDO), Delhi, India \u201dAdditionally, the Acknowledgements were also corrected,\u201cThe authors sincerely thank the Director, INMAS for providing the necessary infrastructural support to accomplish this work. The authors are grateful to Dr. Manju Lata Gupta retired Scientist \u2018G\u2019 and former Project Director, RAKSHAK project for valuable guidance during her tenure. The authors acknowledge Dr. B. G. Roy for providing animals. Support from Mrs. Namita Kalra from INMAS and Dr. Vinay Gupta from BD Biosciences India in the flow-cytometry measurements is duly acknowledged.\u201dnow reads\u201cThe authors sincerely thank the Director, INMAS for providing the necessary infrastructural support to accomplish this work. The authors acknowledge Dr. B. G. Roy for providing animals. Support from Mrs. Namita Kalra from INMAS and Dr. Vinay Gupta from BD Biosciences India in the flow-cytometry measurements is duly acknowledged.\u201dThe Article has been corrected."}
{"text": "Journal of Healthcare Engineering has retracted the article titled \u201cDiagnosis of Blood Vessel Stenosis Caused by Arterial Thrombosis of Lower Extremities by Ultrasound Based on the Mobile Information System\u201d [ System\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifiThe authors do not agree to the retraction."}
{"text": "They also apologize to the readership for any inconvenience caused.Following the publication of the above article, the authors have realized that they inadvertently uploaded an incorrect figure for"}
{"text": "Following the publication of this article , concernThe Fig 4D Occludin panel and the Fig 10A \u03b2-actin panel.Lanes 1\u20132 of the Fig 8A COX2 panel, lanes 1\u20132 of the Fig 8B COX2 panel, and lanes 1\u20132 of the Fig 8C COX2 panel.Lanes 3\u20134 of the Fig 8A COX2 panel and lanes 3\u20134 of the Fig 8B COX2 panel.The Fig 8A \u03b2-actin panel, the Fig 8B \u03b2-actin panel, the Fig 8C \u03b2-actin panel, and lanes 2\u20135 of the Fig 8D \u03b2-actin panel.Lanes 4\u20135 and lanes 6\u20137 of the Fig 9A NF-\u03baB panel.Lanes 1\u20133 of the Fig 9A I\u03baB panel and lanes 1\u20133 of the Fig 9B I\u03baB panel.Lanes 1\u20135 of the Fig 9B NF-\u03baB panel and lanes 1\u20135 of the Fig 9C NF-\u03baB panel.Lanes 4\u20137 of the Fig 9B I\u03baB panel and lanes 4\u20137 of the Fig 9C I\u03baB panel.Lanes 2\u20133 and lanes 4\u20135 of the Fig 10A NRF2 panel.Lanes 1\u20135 and lanes 6\u201310 of the Fig 10C \u03b2-actin panel.The corresponding author stated that the similarities between reference (housekeeping) protein blots are due to the stripping and re-probing of the same blot, and commented that some blot images were spliced to remove extra lanes and/or duplicate or triplicate samples from the panel.The corresponding author provided image data to support the results presented in Figs 8A, 8B and 9A. The underlying data for Fig 8B confirm that the panel has been spliced, but the underlying data provided for Fig 8A and Fig 9A do not appear to match the published panels. Overall, the data did not resolve the concerns about these figures.PLOS ONE in 2014 but are no longer available in the laboratory records. PLOS is unable to access the journal\u2019s 2014 correspondence records for this case. We sincerely regret that this case was not resolved much sooner after the prior correspondence.The corresponding author stated that the underlying data for other figures were provided to PLOS ONE Editors retract this article.Although we have been unable to review the primary data for several figures of concern, the nature and extent of unresolved image data reporting concerns call into question the reliability of the article\u2019s results and conclusions. Therefore, the EL did not agree with the retraction. MCD, AF, SD, AM, CG, YD, and ED either did not respond directly or could not be reached."}
{"text": "The Editor-in-Chief has retracted this article. After publication, concerns were raised regarding the ethics approval for this study. The authors have confirmed that approval from the National Ethics Committee for Health Research in Cambodia was not sought prior to the study.All authors agree to this retraction."}
{"text": "The contrast in"}
{"text": "DOI: 10.1039/D1RA01427G.Correction for \u2018Nano zero valent iron (nZVI) particles for the removal of heavy metals (Cd The correct reference is given below as reference 1.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "The injlium Fig\u00a0."}
{"text": "This article has been corrected at the request of the authors to change the following:The affiliation of Ana C. Spyridakis has been changed from Washington University School of Medicine in St. Louis to St. Louis University.The authors deeply regret that these errors were not identified and addressed prior to publication."}
{"text": "Radiology subspecialisation in Africa: A review of the current status. S Afr J Rad. 2021;25(1):a2168. The original incorrect wording:The Tanzanian IR project was midwifed by the RAD-AID International IR programme in collaboration with academic institutions in the United States and Europe.The revised and updated wording:www.road2ir.org).The Tanzanian IR project was midwifed by the Radiological Society of North America (RSNA) and an organisation called Road2IR (The authors apologise for this error. The correction does not change the significance of study\u2019s findings or overall interpretation of its results or the scientific conclusions in any way."}
{"text": "Please find the retraction statement below:\u201cFollowing publication, concerns were raised regarding the integrity of the images in the published figures. The authors failed to provide a satisfactory explanation during the investigation, which was conducted in accordance with Frontiers\u2019 policies.This retraction was approved by the Chief Editors of Frontiers in Oncology and the Chief Executive Editor of Frontiers.\u201d"}
{"text": "In the Acknowledgments, the name Przemek Prusinekiwcz should appear as: Przemek Prusinkiewicz."}
{"text": "The authors of \u201cEffects of Post-Exercise Whey Protein Consumption on Recovery Indices in Adolescent Swimmers\u201d report an error in"}
{"text": "To reduce monthly bed days for children and young people (CYP) aged under 18 years admitted to adult psychiatric beds by 50%Early senior psychiatric CAMHS review for all CYP admitted to adult psychiatric beds (same or next working day)Increased access to CAMHS medical records for out of hours staffAdmission of all appropriate under 16's to paediatric beds instead of adult mental health bedsShort test of change of staffing CAMHS specialist nurses over a weekendDevelop alternative non-health crisis support/bed for CYPDevelop Personality Disorder (PD) pathwayQI tools used included driver diagram, stakeholder analyses, process mapping, ishikawa diagram, pareto chart and interviews with CYP and carers to gather qualitative data. Monthly data were collected on all admissions of CYP to adult mental health beds. Change ideas/ process changes included:Early senior CAMHS psychiatric review was associated with a reduction in CYP admitted to adult mental health beds from a median of 20 days a month to 2 days a month without an associated increase in CAMHS inpatient admissionsPareto chart showed that Personality Disorder (PD) was the commonest diagnosisAccess to CAMHS medical records for all out of hours psychiatric medical staff was increased from 13% to 100%Routine admission to paediatrics for all under 16's was agreed with paediatric medical and nursing managers but not sustainably implementedThere were no acute referrals to the CAMHS specialist nurses over the single weekend short test of changeDevelopment of an alternative non-health crisis support/bed and development of a Personality Disorder (PD) pathway is still in processThe primary outcome measure was successfully met with the median bed days of CYP admitted to adult mental health beds sustainably reduced from a median of 20 days to 2 days. This was associated with the implementation of routine early senior psychiatric CAMHS review and increased access to CAMHS health records for all medical staff providing psychiatric out of hours assessments. The change ideas including development of different admission pathways , weekend CAMHS specialist nurses service and development of a personality disorder pathway were not implemented sustainably. The pathways of care around CYP presenting in crisis are complex. Making sustainable improvements in complex adaptive systems is complex and challenging but not impossible."}
{"text": "They also apologize to the readership for any inconvenience caused.The authors have re-examined their original data, and realize that"}
{"text": "The Editor apologizes to the readership for any inconvenience caused.Following the publication of the above paper, it was drawn to the Editors' attention by a concerned reader that certain of the lanes shown in the DNA agarose gel electrophoresis experiment in Figs. 2D bore some striking similarities; furthermore, there were unexpectedly similar-looking bands included within the gel slices for the western blotting experiments portrayed in Fig. 3B and C. The Editor of"}
{"text": "Journal of Healthcare Engineering has retracted the article titled \u201cLncRNA MAGI2-AS3 Suppresses the Proliferation and Invasion of Cervical Cancer by Sponging MiR-15b\u201d [Following an investigation conducted by the Hindawi Research Integrity team , signifi"}
{"text": "Retraction Note: BMC Ophthalmol 20, 289 (2020)https://doi.org/10.1186/s12886-020-01565-zThe Editor has retracted this article. After publication, concerns were raised regarding the presented data. Specifically, the flow cytometry plots in Fig. 3a appear not to be representative of the experimental results based on the full data provided by the authors. In addition, the authors used an unsuitable method (Annexin V/PI flow cytometry assay) to distinguish pyroptosis from apoptosis. Furthermore, the western blotting images presented in Fig. 7 do not appear to match the quantitative data in the bar graph. The Editor therefore no longer has confidence in the presented data and the conclusions of this article.Zhijian Li agrees to this retraction. Yamin Wang has agreed to this retraction but not to the wording of this retraction notice. Min Zhang, Ying Sun, Xiaohui Wang, Zhaowei Song, Huazhang Li and Kexin Liu have not responded to any correspondence from the editor or publisher about this retraction."}
{"text": "Applied Bionics and Biomechanics has retracted the article titled \u201cArtificial Intelligence Technique of Synthesis and Characterizations for Measurement of Optical Particles in Medical Devices\u201d [Devices\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifiThe authors do not agree to the retraction."}
{"text": "Ibrahim et al., RSC Adv., 2022, 12, 8030\u20138042, https://doi.org/10.1039/D1RA08530A.Correction for \u2018Electrocatalytic hydrogen generation using tripod containing pyrazolylborate-based copper( The authors regret that an incorrect version of The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Computational Intelligence and Neuroscience has retracted the article titled \u201cMiR-186-5p Downregulates NAMPT and Functions as a Potential Therapeutic Target for Sepsis-Induced Coagulation Disorders\u201d [Following an investigation conducted by the Hindawi Research Integrity team , signifi"}
{"text": "The authors regret that the following funding information was mistakenly omitted from the acknowledgements in the original article: \u201cResearch reported in this article was partially supported by the National Institute of General Medical Sciences of the National Institutes of Health under linked Award Numbers RL5GM118969, TL4GM118971, and UL1GM118970. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.\u201dThe Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "In the previously published paper , there wAcknowledgments: This work is financed by national funds through FCT\u2014Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia, I.P., under the Strategic Project with the references UIDB/04008/2020 and UIDP/04008/2020, and through the scholarship SFRH/BD/144910/2019.There was an error in the original publication. For the 10 cm-wide piece of bimetal under analysis, the natural behavior is to open when cooling and close when heated. When we insert the creases on the active layer, the behavior is the opposite\u2014 it closes when cooling and opens when heated.3.2.3. Experiments with Bimetal: \u201cWe noticed the potential to explore the crease on the active layer once the initial evidence demonstrated an opportunity to manipulate the kinematic behavior of the bimetal. In other words, the crease patterns can lead to an open form when heating and closed when cooling.\u201dA correction has been made to Regarding the scientific interpretation, there is no change. This replacement is to be more explicit about the results. The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "In the original publication , there wResults, 3.2. Horizontal Movement and Behaviour, paragraph 2:There was an error in the original publication. The term \u2018New South Wales\u2019 was used. A correction has been made to In the sentence starting with \u201cW2 entered shelf waters ~3 km from North Stradbroke Island, New South Wales, ~160 km north\u2026\u2026\u201d on line 7, replace the words \u201cNew South Wales\u201d with \u201cQueensland\u201d. It will then read \u201cW2 entered shelf waters ~3 km from North Stradbroke Island, Queensland, ~160 km north\u2026\u2026\u201d.The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "ACS Applied Materials & Interfaces,1 which was not cited in this RSC Advances paper. The RSC Advances paper is a valuable and necessary supplement to the publication in ACS Applied Materials & Interfaces and focused on the reduced gas sensing performance of the devices instead of film characterization and film conductive performance.The authors wish to draw the reader\u2019s attention to their previous related study, published in RSC Advances paper, which should be attributed to The authors regret not giving correct attribution to Fig. 1\u20136 which duplicate data from The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "On page 15, \u201cData availability\u201d should have the following corrections.Volume 5, no. 1, e00795-19, 2020, PRJNA385762 and PRJNA480137. All of the MAGs deposited under PRJNA385762 (n\u2009=\u2009615) are available. For the MAGs deposited under PRJNA480137, three of the seven original data holders provided approval for the release of their MAGs (n\u2009=\u2009747); the rest of the MAGs  are no longer available under accession number PRJNA480137, to avoid the duplication of being analyzed and uploaded to NCBI or other databases by the original data holders.The metagenome-assembled genomes (MAGs) that were resolved in the current study have been deposited at NCBI under BioProject accession numbers PRJNA480137, the original data have been deposited at the Integrated Microbial Genomes & Microbiomes (IMG/M) platform. The IMG identifiers (IDs) and the corresponding owners are provided as follows: 3300005275, 3300005278, 3300005298, 3300007999, 3300008000, 3300008019, 3300009013, 3300009585, and 3300009598 (Brian P. Hedlund); 3300005856 (William P. Inskeep); 3300006767, 3300006799, 3300006808, 3300006809, 3300006865, and 3300006952 (Peter F. Dunfield); and 3300009503 (James G. Elkins).For the MAGs that are no longer available under BioProject accession number The samples were recovered from an inactive black smoker chimney instead of an active black smoker chimney as described in the Introduction of the original paper.Additionally, Fig.\u00a01 is corrected below. The black smoke on the top of hydrothermal vent in Fig. 1c was removed.The authors apologize for these corrections. These mistakes and data availability changes do not influence the general conclusions of the paper."}
{"text": "RSC Advances article due to concerns with the reliability of the data. The images in the article, and the raw data provided by the authors, were screened by an image integrity expert who identified many instances of image manipulation affecting the western blots.The Royal Society of Chemistry hereby wholly retracts this The backgrounds to the western blots in Fig. 1 show splice marks between each pair of bands. The top edge of the FOXO4 control band appears manipulated.In Fig. 2, the top and bottom edges of the two middle bands (Hypoxia + pcDNA3.1) are identical. Analysis of the bands indicates that they are likely to be the stretched versions of the same band.Repeating sections of background have been identified in the HIF-2\u03b1 and Bnip3 panels in Fig. 4. Repeating sections can also be observed in the backgrounds of both blots in Fig. 5.Given the significance of the concerns about the validity of the data in the article, the findings presented in this paper are not reliable.The authors have been informed but have not responded to any correspondence regarding the retraction.RSC AdvancesSigned: Laura Fisher, Executive Editor, th January 2021Date: 7"}
{"text": "Figure 1**. **Change food challenge N = 15 for control to N = 45**. The corrected **Figure 1** appears below.In the original publication , there wFigure 2**. **Change the numbers of the sample sizes and Q value**. The corrected **Figure 2** appears below. In the original publication, there was an error in **There was an error in the original publication. **The percent of participants able to consume 8 g of protein was significantly higher in all mixed protein groups compared to controls (q < 0.01)**.Results**, **page 8**:A correction has been made to ****The percent of participants able to consume 8 g of protein was significantly higher in all mixed protein groups compared to the controls (q < 0.05). There were 44, 14, and 14 participants who had available OFC outcomes in the control, peanut, and mixture high groups, respectively**.The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "Retraction: Cancer Cell International (2021) 21:143 https://doi.org/10.1186/s12935-021-01846-7The Editors in Chief have retracted this article. After publication concerns were raised regarding the expression ranges of LINC01089 in the tumour group in Fig.\u00a01C and in Fig.\u00a03B, an evaluation of the raw data found inconsistencies between the provided data and the data in the graphs. Concerns were also raised regarding irregularities within Fig.\u00a05E, however the authors were unable to provide the full original raw western blot data. The Editors in Chief, therefore, no longer have confidence in the reliability of the results presented in this article. None of the authors have responded to any correspondence from the editor/publisher about this retraction."}
{"text": "Journal of Healthcare Engineering has retracted the article titled \u201cEffects of Equine-Assistant Activity on Gross Motor Coordination in Children Aged 8 to 10 Years\u201d [Following an investigation conducted by the Hindawi Research Integrity team , signifiThe authors disagree to the retraction."}
{"text": "The revised version of"}
{"text": "Bioscience Reports at the request of the Editor-in-Chief and the Editorial Board following receipt of a notification from a reader alerting the Editorial Board to an apparent duplicate region within the si-NC and the miR-143-3p mimic + pcDNA-MSI2 panels of Figure 7H. Additional concerns exist over the western blots within the paper. The authors have been contacted with regards to the retraction and have not responded to the Journal's queries or the concerns raised. Given the extent of the issues raised, the Editorial Board stand by the decision to retract the article.This article is being retracted from"}
{"text": "The authors report a correction of the first equation on page 12 . The \u201cminus\u201d operator should be \u201cplus\u201d in the equation as it shown on the following picture.The authors state that the correction does not affect the results and conclusions of the paper."}
{"text": "Oxidative Medicine and Cellular Longevity has retracted the article titled \u201cMelatonin Attenuates Cardiac Ischemia-Reperfusion Injury through Modulation of IP3R-Mediated Mitochondria-ER Contact\u201d [Contact\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifiThe authors do not agree with the retraction."}
{"text": "Retraction Note:J Exp Clin Cancer Res38, 19 (2019)https://doi.org/10.1186/s13046-018-1010-1Figure 2D: the Oct4 blot looks similar to blot described as CD133 in Fig. 7D of [Figure 4C: one of the actin controls looks very similar to the blot previously published  in Fig. Figure 7B, the actin control appears similar to the Tubulin one in Fig. 4B in a previously-published paper by different authors [Figure 8C, the upper actin control seems similar to the a-tubulin blot in Fig. 4B of a previously-published paper  by diffeFigure 8C, the lower actin control seems similar to the A549 actin control in Fig. 3A of a previously-published paper  by diffeThe Editor in Chief has retracted this article. Although Fig. 9 was corrected in May 2019 [Additionally, the tumour sizes in the corrected Fig. 9 do not appear to match the volume bar chart, and the additional tumours in FigS5A appear too large to meet ethical standards around animal welfare.The authors sent raw photos but were unable to provide the original Western blot images and the ethics approval. The Editor in Chief, therefore, has lost confidence in the integrity of the findings of this article. All authors agree with this retraction."}
{"text": "RSC Advances article due to concerns with the reliability of the data in the published article.The Royal Society of Chemistry hereby wholly retracts this International Journal of Hydrogen Energy article by the same authors,1 which is a high resolution transmission electron micrograph representing Pt/TPA@rGO NPs.The high resolution transmission electron micrograph inset in Fig. 2 that represents Pt NPs/TPrA@VC-AC is a duplicated and rotated version of the inset in Fig. 2a in an RSC Advances article, which is a transmission electron micrograph representing Pt NPs/TPrA@VC, is a duplicated and scaled version of Fig. S2, also in the ESI, which is a transmission electron micrograph representing Pt NPs/TPrA@AC.Fig. S1 in the ESI of this The authors claim that these are mistakes and provided replacement data for consideration. However, an expert reviewed the authors\u2019 response and concluded that it did not satisfactorily address the concerns, and that the replacement figures did not fully support the conclusions. Given the significance of the concerns about the validity of the data, the findings presented in this paper are no longer reliable.Fatih Sen opposes this retraction. Handan Pamuk, Yunus Y\u0131ld\u0131z, Ozlem Karatepe and Zeynep Dasdelen were contacted but did not respond.RSC AdvancesSigned: Laura Fisher, Executive Editor, Date: 23rd September 2021"}
{"text": "The authors apologise for a misspelling of the seventh author\u2019s name: Wei-Jian Wang should instead read Wei-Jan Wang.Also, the following financial support statement was erroneously omitted from the acknowledgements section:This research was supported by China Medical University (CMU109-MF-55 to W.-J.W)."}
{"text": "Retraction Note: J Exp Clin Cancer Res 41, 152 (2022)https://doi.org/10.1186/s13046-022-02356-8Fig. 1c states that co-localization of CD206 and miR-15b-5p is presented, but only images for miR-15b-5p and DAPI are presented.Fig. 1i blots appear to have deleted backgrounds and an artifact in the Calnexin image.Figs. 1b, 3e and 5c use SGC-7901 cells, which are contaminated with HeLa.Fig. 5i MKN-45 data don\u2019t appear to match Fig. S2c.Fig. 7c AGS BRMS1 data don\u2019t appear to match Fig. S2f.Fig. S2a MKN-45 VIM lanes 1 and 2 have similar artifacts on the right side of the bands.The study did not obtain ethics approval prior to the start of the experiment.The authors have retracted this article. After publication, the authors realized there were potential errors with figure labels and the cell lines used in the experiments. Additional checks have identified that:The authors have been able to provide alternative data for Figs. 1i, S2a, c and f to address some of these concerns. However, the cell line and ethics issues could not be resolved.All authors agree to this retraction."}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a satisfactory reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors\u2019 attention by a concerned reader that several of the data panels shown in Fig. 4A were overlapping with panels contained within the same figure, where the panels were intended to portray the results from a range of different cell migration assay experiments. Given the number of overlaps of data that have been identified, the Editor of"}
{"text": "The authors wish to correct the following error in the original paper .An additional affiliation (University of the Basque Country (UPV/EHU), Nieves Cano, 12, 01006, Vitoria-Gasteiz, Spain) has been added to the first author. Due to this change, the numbers of the rest of the affiliations of each author were updated.The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. This correction was approved by the academic editor. The original publication has also been updated."}
{"text": "Correction to genetic variants in LKB1/AMPK/mTOR pathway are associated with clinical outcomes of chemotherapy in non\u2010small cell lung cancerIn Sun Ha Choi et al.The authors noticed that the funding statement is missing. The Funding information section should read:This research was supported by Kyungpook National University Research Fund, 2021.The publisher apologizes for the error and any inconvenience it may have caused."}
{"text": "Cell Death and Disease 10.1038/cddis.2013.465, published online 16 January 2014Retraction to: The vinculin bands in lanes 1\u20132 in Fig. 8b are used to represent vinculin in a different experiment published as Fig. 4A lanes 1\u20132 in [In Fig. 8d the Bim EL, BimL and BimS bands have been duplicated in lanes 4 & 5.In Fig. 8d the p-Akt bands in lanes 4 & 5 have been duplicated.The Editors are retracting this article because of concerns with a number of figures. An investigation by the University of Milan confirmed that:The Editors therefore no longer have confidence in the data.Maria Alfonsina Desiderio does not agree to this retraction. Paola Maroni, Paola Bendinelli, Emanuela Matteucci, Alessia Locatelli and Giorgio Scita have not responded to any correspondence from the editor/publisher about this retraction. The publisher was unable to find up-to-date contact details for Toshikazu Nakamura."}
{"text": "The authors regret that references 77\u201389 were incorrectly given in the original article. The correct references are listed here:RSC Adv., 2015, 5, 51563.77 Y. Xue, Y. Wen, W. Huijuan, M. Liu, X. Huang, X. Ye, X. Wang and B. Li, Chem. Mater., 1997, 9, 210\u2013217.78 G. Zhang, J. Sterte and B. J. Schoeman, Angew. Chem., Int. Ed. Engl., 1997, 36, 477\u2013479.79 R. Murugavel and H. W. Roesky, Kinet. Catal., 2015, 56, 450\u2013455.80 M. G. Clerici, Soft Matter, 2013, 9, 2553.81 A. B. Kayitmazer, D. Seeman, B. B. Minsky, P. L. Dubin and Y. Xu, Langmuir, 2005, 21, 9675\u20139688.82 F. Cousin, J. Gummel, D. Ung and F. Bou\u00e9, ACS Catal., 2017, 7, 2047\u20132051.83 Y. Zhang, Q. Wang and H. Hess, Biochemistry, 1964, 3, 1913\u20131919.84 L. Goldstein, Y. Levin and E. Katchalski, Biochemistry, 1966, 5, 139\u2013143.85 K. Kleppe, Biomacromolecules, 2006, 7, 1245\u20131252.86 C. L. de Vasconcelos, P. M. Bezerril, D. E. S. dos Santos, T. N. C. Dantas, M. R. Pereira and J. L. C. Fonseca, Zeolites, 1992, 12, 943\u2013950.87 A. Thangaraj, M. J. Eapen, S. Sivasanker and P. Ratnasamy, Anal. Biochem., 1996, 236, 302\u2013308.88 T. Zor and Z. Selinger, Anal. Biochem., 1976, 72, 248\u2013254.89 M. Bradford, The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Correction: Mol Cancer 12, 96 (2013)https://doi.org/10.1186/1476-4598-12-96In our BMC Research publication in Molecular Cancer entitled \u2018Histone acetyltransferase PCAF Up-regulated cell apoptosis in hepatocellular carcinoma via acetylating histone H4 and inactivating AKT signaling\u2019 , we regrThe authors all agree to this Corrigendum and are grateful to the Editor of Molecular Cancer for allowing them to have the opportunity to correct these errors. The authors would like to apologize for any inconvenience caused."}
{"text": "Bioscience Reports at the request of the authors. Further experiments performed by the authors showed that LncRNA AWPPH had no promotion of cell growth in HCC38, HCC1187 or 4T1. Thus, the conclusion that LncRNA AWPPH is a tumor promoter in TNBC should be further studied to validate the results.This article is being retracted from The Editor-in-Chief and Editorial Board agree with the retraction."}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors\u2019 attention by a concerned reader that the western blotting data in Fig. 5A and certain of the cell migration and invasion assay data shown in Fig. 5C were strikingly similar to data appearing in different form in other articles by different authors. Owing to the fact that the contentious data in the above article had already been published elsewhere, or were already under consideration for publication, prior to its submission to"}
{"text": "Sci., 2022, 13, 2456\u20132461, https://doi.org/10.1039/D1SC06459B.Correction for \u2018An engineered third electrostatic constriction of aerolysin to manipulate heterogeneously charged peptide transport\u2019 by Hongyan Niu  The authors regret an error in the spelling of Meng-Yin Li\u2019s name in the original manuscript. The correct spelling is as shown in this Correction article.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "In the original publication , there wThe authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. The original publication has also been updated."}
{"text": "Journal of Healthcare Engineering has retracted the article titled \u201cMicroRNA-489 Promotes the Apoptosis of Cardiac Muscle Cells in Myocardial Ischemia-Reperfusion Based on Smart Healthcare\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifiThe authors do not agree to the retraction."}
{"text": "This article has been retracted\u00a0after an investigation was conducted by senior faculty and leadership at the\u00a0Institute of Medical Sciences, Banaras Hindu University. This retraction is the result of a dispute between authors regarding authorship as well as the presence of incorrect and incomplete information. Dr. Uma Pandey initially contacted the journal with these concerns and, after an investigation by\u00a0the\u00a0Institute of Medical Sciences, Banaras Hindu University and failure among the authors to come to an agreement regarding amended authorship and corrections, we have elected to retract the article as suggested by Dr. Pandey and senior faculty and leadership\u00a0at the\u00a0Institute of Medical Sciences, Banaras Hindu University. Issues raised by Dr. Pandey and corroborated by the investigation include: missing authors, incorrect author placement for Dr. Pandey and others, and incorrect/incomplete information. Dr. Pandey and the journal regret that these disputes were not handled accordingly prior to submission."}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors\u2019 attention by a concerned reader that certain of the cell migration assay data shown in Fig. 2C were strikingly similar to data that had appeared in different form in other articles by different authors. Owing to the fact that the contentious data in the above article had already been published elsewhere, or were already under consideration for publication, prior to its submission to"}
{"text": "Retraction Note: Journal of Hematology & Oncology (2019) 12:135https://doi.org/10.1186/s13045-019-0830-6The Editor in Chief has retracted this article because of a number of further image irregularities in the figures were found after publication of a correction . SpecifiJiwei Guo does not agree to this retraction. Dan Jin, Yan Wu, Jing Du, Lijuan Yang, Xiaohong Wang, Weihua Di, Baoguang Hu, Jiajia An, Lingqun Kong, Lei Pan and Guoming Su did not respond to correspondence from the Editor about this retraction."}
{"text": "The journal and Chief Editors have retracted the 19 July 2021 article cited above.Shortly after publication, our office received letters of complaint questioning the integrity of the article, following which an Expression of Concern was published and a thorough investigation was conducted, in accordance with our policies and COPE guidelines.The investigation found that the claims made in the conclusions were not adequately supported by the methodology of the study. In particular, as confirmed by an external expert, the process of allocation to treatment and control was not sufficiently random.This retraction was approved by the Chief Editors of Frontiers in Medicine and the Chief Executive Editor of Frontiers. The authors disagree with this retraction."}
{"text": "POU2F2 and not the protein of SLC22A2, as intended. The correct legend appears below.In the original publication , there wThe authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "Understanding the role of inflammation in developing respiratory illnesses such as COPD, asthma, and lung cancer, is critical. Natural cures are regaining favor as effective treatments for various ailments . A flavThe authors declare no conflict of interest."}
{"text": "In the original publication , there wThe authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "Acknowledgments Section:There was an error in the original publication . A correAcknowledgments: We thank K. Shashok for editing the use of English in this manuscript. The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "The authors of this paper  have agrThe updated authorship is listed as below:Donatella Marazziti, Beatrice Buccianelli, Stefania Palermo, Elisabetta Parra, Alessandro Arone, Maria Francesca Beatino, Lucia Massa, Barbara Carpita, Filippo M. Barberi, Federico Mucci and Liliana Dell\u2019Osso. The updated author contribution is as follows:Author Contributions: D.M., B.B., S.P., E.P., L.M., L.D. and F.M. planned the review study. D.M., F.M., B.C., F.M.B., A.A., M.F.B. and L.D. revised all the specific literature. D.M., S.P., E.P. and L.M. wrote the first version of the paper, which was subsequently revised and approved by all authors. All authors have read and agreed to the published version of the manuscript.The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. The original publication has also been updated."}
{"text": "DOI: 1039/C3RA43120GExpression of concern for \u2018Layer-by-layer aqueous synthesis, characterization and fluorescence properties of type-II CdTe/CdS core/shell quantum dots with near-infrared emission\u2019 by Rijun Gui  However, they have not been able to provide a satisfactory explanation for all of the duplicated images that appear in the later publications. An expression of concern will continue to be associated with this article until we are able to obtain conclusive evidence about the reliability of this RSC Advances article.Laura FisherDate: 21st September 2020Executive Editor, RSC Advances"}
{"text": "After having been in contact with the authors, they agreed with the decision to retract the paper. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors' attention by a concerned reader that certain of the immunohistochemical data shown in Fig. 4C and the cell migration assay data shown in Fig. 3B and D and Fig. 7B and D were strikingly similar to data that had appeared in different form in other articles by different authors. Owing to the fact that the contentious data in the above article had already been published elsewhere, or were already under consideration for publication, prior to its submission to"}
{"text": "It should have shown a magnification of the bottom left image. In The authors regret that"}
{"text": "Retraction Note: Mol Cancer 16, 18 (2017)https://doi.org/10.1186/s12943-017-0586-yThe Editor-in-Chief has retracted this article. After publication, the authors requested corrections to Figs. 1F, 3A and 3C due to image misuse. Subsequently, concerns were raised regarding similarity between Fig. 1F (top left panel) in this article and Fig. 3C (bottom right panel) in another article [In Fig. 2C, the flow cytometry analysis for SGC-7901 cells uses inconsistent gating .In Fig. 5G, there appears to be high similarity between the p-AKT western blot images .Further checks by the Publisher have identified the following:The authors have provided raw data to address these concerns. However, the data contain further discrepancies. The Editor-in-Chief therefore no longer has confidence in the presented data.Dan Xie has not responded to any correspondence from the editor or publisher about this retraction. Sheng Ye has stated on behalf of the remaining co-authors that they disagree with this retraction."}
{"text": "Computational Intelligence and Neuroscience has retracted the article titled \u201cEffect of Core Strength Training on Rehabilitation of Chronic Low Back Pain in Aerobics Athletes\u201d [thletes\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifi"}
{"text": "Supplementary Materials were not included. The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. The original publication has also been updated.The authors wish to make the following correction to this paper . In the Supplementary Materials: The following supporting information can be downloaded at: https://www.mdpi.com/article/10.3390/children9040569/s1, Table S1: differences between HLA-B27 positive and HLA-B27 negative twins; Table S2: differences between HLA-B27 positive twins and juvenile spondyloarthritis subjects."}
{"text": "Applied Bionics and Biomechanics has retracted the article titled \u201cBiomechanical Research on Special Ability of Long Jump Take-Off Muscle Based on Multisource Information Fusion\u201d [ Fusion\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifiThe authors do not agree to the retraction."}
{"text": "Retraction Note: BMC Complement Med Ther 20, 54 (2020)https://doi.org/10.1186/s12906-020-2834-8In Fig. 3A, subpanels b and c appear to overlap, with several cells missing from subpanel b.In Fig. 5a, subpanels e and f appear to overlap, but have different brightness.The Editors have retracted this article. After publication, concerns were raised regarding partial image overlap. Specifically:The authors have only been able to retrieve parts of the original data. The Editors therefore no longer have confidence in the data presented in this article.All authors agree to this retraction."}
{"text": "In the article , there i1 was incorrect in Table\u00a0The OR value 6.74 for BSACorrespondingly, the following sentence on page 941,The treatment (BSA) dominates the other variables and increases the odds of healing by 6.74 (P\u00a0=\u00a0.00015).Should have read:The treatment (BSA) dominates the other variables and increases the odds of healing by 6.7 (P\u00a0=\u00a0.00015)."}
{"text": "In view of the fact that these apparent duplications of data have come to light, the Editor of Oncology Reports has decided that this paper should be retracted from the Journal. The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a satisfactory reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors' attention by a concerned reader that certain of the mouse images shown in Fig. 5A and the flow cytometric assay data shown in Fig. 4A and B were strikingly similar to data appearing in different form in other articles written by some of the same authors, but which had already been published elsewhere or were already under consideration for publication, prior to this paper's submission to"}
{"text": "Computational and Mathematical Methods in Medicine has retracted the article titled \u201cAnalysis of the Role of Comprehensive Treatment Model in the Treatment of Prostate Cancer\u201d [ Cancer\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifiThe authors agree to the retraction."}
{"text": "Viruses entitled \u201cNucleocapsid (N) gene mutations of SARS-CoV-2 can affect real-time RT-PCR diagnostic and impact false-negative results\u201d [The authors hereby request the inclusion of two authors (Olivia Teixeira and Maria Cristina Nonato) in the recently published article in results\u201d . As already demonstrated to the Journal, the authors Olivia Teixeira and Maria Cristina Nonato were very important contributors of this article as they were solely responsible for the analysis of the protein structure and the effects of the SARS-CoV-2 mutations on its function at RNA and protein levels. They also collaborated in the discussion of results and the preparation of Figure 2 of the protein structure. Therefore, Olivia Teixeira and Maria Cristina Nonato have to be part of this article as authors. Their names are added between Luiz Carlos Junior de Alcantara and Loyze Paola Oliveira de Lima. All authors have agreed on this change. An additional affiliation, 6, is added in regard to the addition of two authors (Olivia Teixeira and Maria Cristina Nonato). The numbers of other affiliations have been adjusted accordingly. Newly added affiliation 6: Ribeirao Preto Protein Crystallography Laboratory, School of Pharmaceutical Sciences, University of S\u00e3o Paulo, Ribeirao Preto 14040-903, S\u00e3o Paulo, Brazil.In the published publication, there was an error regarding the affiliation for \u201cDimas Tadeu Covas\u201d. In addition to affiliation \u201c2\u201d, the updated affiliation should include: \u201c8, Blood Center of Ribeir\u00e3o Preto, Ribeir\u00e3o Preto Medical School, University of S\u00e3o Paulo, Ribeir\u00e3o Preto 14051-060, S\u00e3o Paulo, Brazil\u201d.The contributions of Olivia Teixeira and Maria Cristina Nonato were not included in the original publication. The corrected Author Contributions Statement appears here. Author Contributions: Conceptualization and designed the experiments: H.F.; performed the analysis: J.C.C.L., M.D.P., O.T. and M.C.N.; analyzed the data: J.C.C.L., H.F., E.C.d.M.O., G.R., L.G.C., O.T. and M.C.N.; writing\u2014original draft preparation: J.C.C.L.; writing\u2014review and editing: J.C.C.L., M.D.P., M.G., S.K. and H.F.; Molecular screening and produced SARS-CoV-2 genomic data: J.C.C.L., M.D.P., E.C.d.M.O., J.S.L.P., L.G.C., V.L.V., M.G., L.C.J.d.A., L.P.O.d.L., A.J.M., C.R.d.S.B., E.C.M., J.d.S.T.B., D.B.M., R.A.B., R.d.L.R.C.C., P.D.S.C.M., S.N.S., R.B.d.S., E.S.R., E.V.S., J.S.B., D.G.L.d.L.R., J.P.K., B.S., P.A.A., F.A.d.S.d.C., C.A.B., L.S., M.M.M., M.P., F.E.V.d.S., R.M.T.G., J.A.S.-N., M.L.N., L.L.C., R.T.C., R.M.N., D.T.C., S.C.S., M.C.E., S.K., H.F. All authors have read and agreed to the published version of the manuscript.The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "Gad et al., RSC Adv., 2022, 12, 19209\u201319224, https://doi.org/10.1039/D2RA03177A.Correction for \u2018Modification of silica nanoparticles by 2,4-dihydroxybenzaldehyde and 5-bromosalicylaldehyde as new nanocomposites for efficient removal and preconcentration of Cu( In \u22121. The corrected versions of the tables are shown below.The authors regret that the units of the concentration in The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Signal Transduction and Targeted Therapy 10.1038/s41392-022-00885-4, published online 02 March 2022Correction to: 1, the authors noticed the inadvertent mistakes occurred in Fig. After online publication of the articleThe authors mistakenly switched \u201c4h\u201d and \u201c1d\u201d UMAP plots. The correct version of Fig. The authos mistakenly spelled \u201cLeukocyte\u201d as \u201cLeukecyte\u201d. The correct version of Fig."}
{"text": "J Clin Invest. 2022;132(7):e148667. https://doi.org/10.1172/JCI148667Original citation: J Clin Invest. 2022;132(19):e165107. https://doi.org/10.1172/JCI165107Citation for this corrigendum: http://genomics.cicbiogune.es/CANCERTOOL/index.html), the two panels included in The authors recently became aware that, following the recent update of Cancertool  breast cancer dataset (OSM in the Wang (20) dataset did not reveal a significant association with disease-free survival  and disease-free survival (DFS) data for breast cancer patients based on OSM mRNA expression in the METABRIC (19) and Wang (20) datasets were analyzed and represented using the CANCERTOOL interface (59) in combination with cBioPortal .The authors regret the errors."}
{"text": "Furthermore, they apologize to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the attention of the Editorial Office by a concerned reader that the western blots featured in"}
{"text": "In the original publication , there w\u22121 to 3.66 \u00b1 0.55 S m\u22121 when 2 w/v% of MXenes were added into the ADA-GEL\u201d should be changed to \u201c\u2026and the conductivity increased from 0.299 \u00b1 0.063 S m\u22121 to 0.366 \u00b1 0.055 S m\u22121 when 2 w/v% of MXenes were added into the ADA-GEL\u201d.In Section 3.2, paragraph 2: \u201c\u2026and the conductivity increased from 2.99 \u00b1 0.63 S mThe authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "Retraction Note: BMC Cancer 21, 1310 (2021)https://doi.org/10.1186/s12885-021-08923-0The Editor has retracted this article at the corresponding author's request. After publication, the authors became aware that their MHCC-97H and HCCLM3 cell lines were contaminated with HepG2, which affected the results of the FAM83H-AS1 overexpression experiment. The authors therefore no longer have confidence in the conclusions of this article.All authors agree to this retraction."}
{"text": "This article has been corrected at the request of the authors to remove the following sentence from the discussion section:\u201cAdditionally, a parallel study of the direct physiologic effects of this technique on an animal model - and comparison to commercial nerve-wrap products - is ongoing in our laboratory.\u201dSuch a study is not ongoing in the lab and has not been completed.The authors deeply regret that these errors were not identified and addressed prior to publication."}
{"text": "The authors also apologize for any inconvenience caused.The corrected versions of"}
{"text": "Computational Intelligence and Neuroscience has retracted the article titled \u201cMonitoring and Analysis of Youth Sports Physique by Intelligent Medical Robot Based on Cognitive Computing\u201d [mputing\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifi"}
{"text": "The authors would like to make the following correction to the published paper .The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated.In the original publication, there were some errors in the affiliation(s) for Masayuki Tanaka, Sanae Isaki, Keiko Yokoyama and Akira Miyajima. The corrected affiliations appear below. 1,*,\u2020, Hakushi Kim 2,*,\u2020, MasaTomoyoshi Komiyama 3, Sanae Isaki 3, Keiko Yokoyama 3, Akira Miyajima 4 and Hiroyuki Kobayashi 1yuki Tanaka 1\u00a0hkobayas@is.icc.u-tokai.ac.jpDepartment of Clinical Pharmacology, Tokai University School of Medicine, Isehara 259-1193, Kanagawa, Japan; 2\u00a0Department of Urology, Tokai University Hachioji Hospital, Tokyo 192-0032, Tokyo, Japan3\u00a0matanaka@tokai-u.jp (M.T.); sanaei@tsc.u-tokai.ac.jp (S.I.); kekoyoko@tsc.u-tokai.ac.jp (K.Y.)Medical Science College Office, Tokai University, Isehara 259-1193, Kanagawa, Japan; 4\u00a0akiram@tokai.ac.jpDepartment of Urology, Tokai University School of Medicine, Isehara 259-1193, Kanagawa, Japan; *komiyama@tokai-u.jp (T.K.); qblong888@gmail.com (H.K.); Tel.: +81-463-93-1121 (T.K.)Correspondence: \u2020These authors contributed equally to this study."}
{"text": "After having been in contact with the authors, they agreed with the decision to retract the paper. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors attention by a concerned reader that the cell migration and invasion assay data shown in Figs. 2F, 5D and 6D were strikingly similar to data appearing in different form in other articles by different authors. Owing to the fact that the contentious data in the above article had already been published elsewhere, or were already under consideration for publication, prior to its submission to"}
{"text": "The retraction has been agreed because there are inconsistencies in Figures 1 and 5 that render the data difficult to interpret and the original data could not be provided to support the conclusions. The authors asked to retract the manuscript because their confidence in the results has been undermined by these inconsistencies.The following article, published online on 20 January 2020 in Wiley Online Library ("}
{"text": "The authors regret to declare that a Table that appears in the published article  presenteThe authors apologize for any inconvenience caused."}
{"text": "Journal of Healthcare Engineering has retracted the article titled \u201cPreparation of Bismuth Tungstate Nanomaterials with Different Morphologies and Their Effect on Exercise Rehabilitation of Patients with Lumbar Disc Herniation\u201d [niation\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifi"}
{"text": "Signal Transduction and Targeted Therapy (2022) 7:298; 10.1038/s41392-022-01149-x, published online 28 August 2022Correction to: 1 the authors noticed the order of Figs. After online publication of the review,"}
{"text": "Padghan  RSC Advances article following an institutional investigation carried out by RMIT University.The Royal Society of Chemistry, with the agreement of the authors, hereby wholly retracts this Fig. 1 contains several identical vials representing different experiments.The investigation found that this paper \u201cbreached the Australian Code and RMIT Research Policy by not ensuring that conclusions are justified by the results and not responsibly disseminating research findings\u201d. A recommendation was given that this paper is retracted.Dr Sachin D. Padghan was fully responsible for the error that happened in the figure. All other authors Rajesh S. Bhosale, Namdev V. Ghule, Avinash L. Puyad, Sheshanath V. Bhosale and Sidhanath V. Bhosale are not responsible for this error.Signed: Sachin D. Padghan, Rajesh S. Bhosale, Namdev V. Ghule, Avinash L. Puyad, Sheshanath V. Bhosale and Sidhanath V. BhosaleDate: 09/01/2023"}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors\u2019 attention by a concerned reader that various panels showing cell migration assay data in Figs. 3B and C and 5C and D were strikingly similar to data appearing in different form in other articles by different authors. Furthermore, overlapping data panels were identified within this paper comparing the cell migration assay images between Figs. 3B and 5C. Owing to the fact that the contentious data in the above article had already been published elsewhere, or were already under consideration for publication, prior to its submission to"}
{"text": "Communications Biology 10.1038/s42003-022-04232-9, published online 19 November 2022.Correction to: The Peer Review File that was originally published with the Article contained confidential data which the authors only intended to disclose to the peer reviewers. Figures containing the confidential data have now been redacted from pages 15, 22, 23, 38, and 45 of the Peer Review File."}
{"text": "The authors regret that the original version of our paper unfortunately contained incorrect data in Figure The corrections made in this erratum do not affect the original conclusions. The authors apologize for any inconvenience that the errors may have caused."}
{"text": "There was an error in the original publication . We mistA correction was implemented in Section 1 in the second paragraph of the Introduction:\u201c\u2026an estimated 100,000 pet ferrets in the UK [13]\u201d.The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "The Editor-in-Chief has retracted this article. After publication, concerns were raised regarding image overlap across various panels in Fig.\u00a08. The authors have stated that incorrect images were used, but have been unable to provide the full raw data. Additionally, the authors could not justify the anesthetic protocol used for rat stereotaxic surgery.\u00a0The Editor-in-Chief therefore no longer has confidence in the presented data and ethics of this article.Author Haichen Niu has stated on behalf of all co-authors that they agree to this retraction."}
{"text": "Funding: This project was funded by The Deputyship for Research & Innovation, Ministry of Education in Saudi Arabia, the project no. (IFKSURG-2-940).Acknowledgments: The authors extend their appreciation to the Deputyship for Research & Innovation, Ministry of Education in Saudi Arabia for funding this research work through the project no. (IFKSURG-2-940).In the original publication , the funThe authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "Dear Dr. Rujittika Mungmunpuntipantip,Thank you for your letter and comments on the paper. The paper described by Ong et al. focuses on the safety and adverse events among the PWE following COVID\u201019 immunization. Some of the recruited subjects in the paper have other comorbidities, which do not deter them from being vaccinated. Some adverse events are inevitable, which are not proven to be more frequent or more severe compared with the general population. All in all, the benefits of COVID\u201019 vaccination outweigh its potential risks.We confirm that we have read the Journal's position on issues involved in ethical publication and affirm that this report is consistent with those guidelines. Neither of the authors has any conflict of interest to disclose for this letter.Thank you.Best regards,Corresponding author:Ching Soong Khoo.Department of Medicine,Universiti Kebangsaan Malaysia Medical Centre.chingsoongkhoo@gmail.comEmail: Lead author:Marjorie Jia Yi Ong.The National University of Malaysia.marjorieongjiayi@gmail.comEmail:"}
{"text": "The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. The authors agree with this correction. This correction was approved by the Academic Editor. The original publication has also been updated.We received a complaint from the Universit\u00e9 Catholique de Louvain. In the published version of the article , there w"}
{"text": "Scientific Reportshttps://doi.org/10.1038/srep20879, published online 12 February 2016Addendum to: Concerns have been raised post-publication about the similarity between the WT and APP/PS1 images in Figure"}
{"text": "In an articleAll the transmission electron microscope images  are uploaded in error and these are corrected in the figures below.Figure 1Figure 3Figure 6The authors apologize for the error."}
{"text": "In the original publication , there wThe categories in the bar charts in In the original publication, there was a formatting error in The relevant section of the corrected The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "Retraction Note: BMC Biochem 13, 25 (2012)https://doi.org/10.1186/1471-2091-13-25The Editors have retracted this article. After publication, concerns were raised about the origin in the images in Fig. 3b. The authors provided raw data to address these concerns, but the data contained image duplication between different groups and different repeats of the experiment. The Editors therefore no longer have confidence in the presented data.Authors Gongjun Tan, Guangrong Yan, Wenhua Mei and Faqing Tang have not responded to any correspondence from the editor or publisher about this retraction notice. The Editor has not been able to obtain current email addresses for authors Yuejin Li, Na Liu, Damao Huang, Zhenlin Zhang, Zhengke Peng, Chaojun Duan and Xiaowei Tang."}
{"text": "PLoS Medicine, PLoS Biology, PLoS One, PLoS Computational Biology, PLoS Genetics, PLoS Pathogens, and PLoS Neglected Tropical Diseases) between January 2010 and December 2020 were extracted from Web of Science. Using Genderize.io, the gender of authors from their first names was estimated using a 75% threshold. The association between female prevalence in first and last authorship and journal was evaluated using a binary logistic regression, and odds ratios were estimated against a 50:50 reference on gender. In 266,739 publications, 43.3% of first authors and 26.7% of last authors were females. Across the ten-year period, female first authorship increased by 19.6% and last authorship by 3.2%. Among all journals, PLoS Neglected Tropical Diseases had the greatest total proportion of female first authors (45.7%) and PLoS Medicine of female last authors (32%), while PLoS Computational Biology had the lowest proportion in these categories (23.7% and 17.2%). First authors were less likely to be females in all PLoS journals (p < 0.05) except for PLoS Neglected Tropical Diseases , where the odds of female authorship were not significantly different (p = 0.054). Last authors were not more likely to be females in all PLoS journals (p < 0.001). Overall, women still appear underrepresented as first authors in biomedical publications and their representation as last authors has severely lagged. Efforts towards gender equality in scholarly authorship will contribute to the representation of women in biomedical research and ensure that their potential is not lost.Women are generally underrepresented in science, technology, engineering, and mathematics (STEM). As scientific production reflects scholarly impact and participation in the scientific process, the number of journal publications forms a pertinent measure of academic productivity. This study examined the prevalence and evolution of female representation in prominent author positions across multidisciplinary biomedical research. Publications from seven exemplar cross-specialty journals of the Public Library of Science ( The proportion of women who are engaged academically and professionally across the fields of science, technology, engineering, and mathematics (STEM) has been increasing in recent decades . HoweverThere has also been considerable gender inequality in the authorship of scientific production and throughout the publication process itself. Evidence from a series of studies, have highlighted a significant underrepresentation of women in prominent author positions ,12,13,14A plethora of studies have already attempted to describe the overall publication trends of female authors across STEM but without addressing this in areas of interdisciplinary biomedical research . A majorAdvancement within the academic ladder is largely contingent on scientific production and scholarly impact. Widely available metrics pertained to academic productivity and scientific influence include the publication number of peer-reviewed research. In our study, we aimed to examine the prevalence and evolution of female representation in prominent author roles\u2014first and last authorship\u2014and determine whether quantifiable gender differences across multidisciplinary biomedical research, exist. To accomplish the purpose of our study, we focused as an example on publications from seven cross-specialty OA journals of the Public Library of Science (PLoS) between 2010 and 2020.We examined the prevalence of female first and last authors in publications from seven PLoS journals between 1 January 2010 and 31 December 2020. Initially, we selected these as they offer a representation of an exemplar sample of multidisciplinary biomedical research because of their cross-speciality series of journals. Thereafter, as the journals operate on OA and thus, article processing charges apply to publishing, authorship trends observed here may reflect the contribution of grant-funded researchers and their inclusion. Lastly, focusing on a single publisher allows for horizontal comparisons to be made more appropriately since different publishers may have variable priorities for publishing different or specific types of studies.http://scientific.thomson.com/products/wos/ (accessed on 5 February 2021) to retrieve full bibliographic records of all peer-reviewed publications from each year in PLoS Medicine, PLoS Biology, PLoS One, PLoS Computational Biology, PLoS Genetics, PLoS Pathogens, and PLoS Neglected Tropical Diseases. All types of publications were considered in our study and hence, our search on WoS was only limited to the aforementioned journal titles as search terms. No exclusion criteria were applied in our search strategy to avoid selection bias.We performed a literature search using the Web of Science (WoS) database ; Demografix ApS, Roskilde, Denmark) by determining the likelihood of association between their first names and a binary gender category. This gender prediction method utilises known genders collected from user profiles on major social networks. To assign names with a specific gender , we used a 75% probability threshold. Authors whose gender could not be determined based on their first names (classified as \u201cUnknown\u201d) were excluded from all further analyses.The gender of the first and last authors was predicted using the Genderize.io database . Statistical significance was established as Our initial search yielded 266,739 publications from seven cross-specialty PLoS journals, between 2010 and 2020. Among these, 262,122 publications were eligible for first-author gender prediction, with the remaining 4617 (1.8%) publications being omitted (non-listed authors (N = 292), single-named authors (N = 2), and authors with initials (N = 4323)). Similarly, 261,799 publications were suitable for last-author gender prediction and 4940 (1.9%) publications were excluded (non-listed authors (N = 292), single-named authors (N = 190), and authors with initials (N = 4458)). Ultimately, we were able to predict the gender of 211,404 (79.3%) first authors and 221,794 (86.1%) last authors. Of the first authors, 91,619 (43.3%) were female, while of the last authors, 59,208 (26.7%) were female.PLoS Neglected Tropical Diseases had the greatest total proportion of female first authors  and PLoS Medicine of female last authors  over the ten-year period, while PLoS Computational Biology had the lowest proportion in these categories   and female last authors  in 2020, while PLoS Computational Biology had the lowest proportion in these categories   . Further; 19.5%) .PLoS One (32.9%) and in female last authorship in PLoS Medicine (14.1%). The lowest change in female first authorship was in PLoS Biology (\u22121.9%) and in female last authorship in PLoS Genetics (2.3%)  .PLoS Pathogens (odds ratio (OR): 0.83, 95% confidence interval (CI): 0.70\u20130.99, p = 0.035), PLoS Genetics , PLoS Medicine , PLoS One , PLoS Biology , and PLoS Computational Biology ], except for PLoS Neglected Tropical Diseases , where the odds of female authorship were not significantly different. By contrast, females had statistically significant lower odds for last authorship in all PLoS journals  ] .PLoS Computational Biology had the lowest total proportion in female first and last authorship over the ten-year period and in 2020, with overall less than a fourth of first authors and almost a fifth of last authors, as females. Nevertheless, our results showed a slow narrowing of the gender gap for first authors and last author positions. Indicative of this, PLoS Neglected Tropical Diseases had the greatest total proportion among first authors with almost a half as females, and PLoS Medicine among last authors with more than a third being females. Equally, female firth authorship increased highest, by a third, in PLoS One and female last authorship by less than a fifth in PLoS Medicine. Our findings highlighted a gender gap in first and last authorship across publications from seven OA cross-specialty PLoS journals in biomedical research, between 2010 and 2020. We demonstrated that less than a half of the first authors and almost a fourth of the last authors, were females. Likewise, female first authorship increased by 21.2% and last authorship by 7.9% across the ten-year period. Indeed, first and last authors were less likely to be females in the majority of PLoS journals. We have identified a continuous increase in the representation of women among first and last authors across most PLoS journals between 2010 and 2020. Although our data did not allow us to unveil the underlying mechanism of this change, our results consistently demonstrated that a gender gap in scientific authorship still exists, especially among last authors. While there are no prior studies examining gender authorship in PLoS journals, our findings are in line with previous reports that focused on different but relevant biomedical journals, pointing out an increasing trend in the prevalence of female first authorship, but with that, last authorship is yet to catch up. Specifically, a study which examined the gender distribution across the biosciences and within the entire JSTOR corpus highlighted a more pronounced decrease, specifically in the number of female last authors as opposed to that in first authors which was less severe .Multiple inter-connected explanations could likely underlie our observation. Firstly, there may be a \u201cleaky pipeline\u201d with each step up in the academic ladder, a phenomenon which has long been described and acknowledged by the scientific literature ,37,38. DPLoS Neglected Tropical Diseases and PLoS Computational Biology\u2014have greatly opposing patterns in female representation across first and last authorship. To date, there are no previous studies looking at the prevalence of gender authorship in the field of neglected tropical diseases across the biomedical literature. However, reports have highlighted an underrepresentation of women in infectious diseases research. In a review examining gender parity in The Lancet Infectious Diseases, females constituted 32% of first authors and 22% of last authors between 2014 and 2017 [Our results also demonstrated that two prominent PLoS journals\u2014and 2017 . Howeverand 2017 . Neverthand 2017 . Thus, iMoreover, there is ample literature on the unequal distribution between genders in STEM across all aspects of scientific and academic practice. Yet, there are only a few studies examining gender authorship in interdisciplinary fields such as computational biology and a lot more about its parent fields of biology and computer science. When looking in doctoral degrees awarded to women, computer science has the lowest share of recipients, while in biology, more than a half of degrees are held by women . Within Our study provided interesting insights about female dynamics in authorship among PLoS journals in biomedical research, yet methodological and conceptual limitations exist. Primarily, we inferred gender of authorship using the Genderize.io database which is based on user profiles from social networks, that may contain arbitrary words or characters which could have contributed to a less accurate gender estimation . SimilarOur study showed that women are underrepresented in seven cross-specialty PLoS journals and confirms previous studies done in other journal sets and disciplines. Although our findings highlighted a slow narrowing of an existing gap among female first authors, women\u2019s representation as last authors has severely lagged behind. This reinforces the potential attrition of women in academic career advancement with probable barriers at the levels of research support, dedicated research time, or the publication process itself. Our study reinforced that we cannot yet disregard disparities in female authorship and hint that this matter warrants renewed attention. While proposing interventions towards gender equality was beyond the focus of our study, we should emphasise their importance in maximising the contribution of women in research and ensuring that their potential is not lost."}
{"text": "Following publication, concerns were raised regarding the integrity of the images in the published figures. The authors failed to provide a satisfactory explanation during the investigation, which was conducted in accordance with Frontiers\u2019 policies.Given the concerns, the editors no longer have confidence in the findings presented in the article.The authors do not agree to this retraction.This retraction was approved by the Chief Editors of Frontiers in Cell and Developmental Biology and the Chief Executive Editor of Frontiers."}
{"text": "Leukemia cutis is a cutaneous manifestation of leukemia. Herein, we present a rare cutaneous manifestation of leukemia cutis in a patient with myeloid leukemia m5, characterized by hyperpigmented red\u2010to\u2010brown patches on face and upper trunk. To our knowledge, hyperpigmented patches secondary to leukemia cutis is rarely described in the literature. Leukemia cutis is a cutaneous manifestation of leukemia. Herein, we present a rare cutaneous manifestation of leukemia cutis in a patient with myeloid leukemia m5, characterized by hyperpigmented red\u2010to\u2010brown patches on face and upper trunk. To our knowledge, hyperpigmented patches secondary to leukemia cutis is rarely described in the literature. The patient presented with hyperpigmented patches on the face and upper trunk with ocular and oral mucosal changes upon examination. Further workup revealed patient having acute myeloid leukemia (AML\u2010M5), and skin biopsy showed infiltration with myeloblasts.23/L with neutrophil and lymphocyte differentiation , hemoglobin 10.5\u00a0g/dl, and platelet count of 72\u2009\u00d7\u2009103 \u03bcl.A 76\u2010year\u2010old man with no significant past medical history presented to our clinic with a 6\u2009months skin hyperpigmentation and fatigue. The patient was treated with skin\u2010lightening and antisolar creams but with no improvement. Clinical examination showed brown to violet hyperpigmented patches on face and upper trunk. Mucosal examination showed violaceous plaques on the upper palate in addition to yellow sclera with red to purple patches on the inner aspect of both lower eyelids Figure\u00a0. PhysicaTwo skin biopsies from face and chest were taken with differential diagnoses of angiosarcoma, lymphoma, and lichen planus. The result showed dense dermal multinodular perivascular and periadnexal infiltration with atypical mononucleated cells with IHC evidence consistent with leukemic dermal infiltration Figure\u00a0. Immunoh3Patients with underlying hematologic malignancies can present with a diversity of non\u2010specific reactive skin lesions or specific infiltrates.In addition to usual typical skin manifestations, the recorded unusual manifestations of leukemia cutis were summarized in retrospective study in 2021 by Yung\u2010WeiChang, which included leonine faces, figurate cutaneous lesions, fingertip hypertrophy, erythema nodosum, guttate psoriasis, chronic paronychia, leukemic vasculitis, and Sister Mary Joseph's nodule.Our patient was complaining of hyperpigmented patches on the face and upper trunk from 6\u2009months before presenting to our clinic, and unfortunately, the patches were treated as skin pigmentation.Involvement of skin can be seen in any leukemia subtype, but most commonly seen in acute myeloid leukemia (AML) with monocytic or myelomonocytic and chronic lymphocytic leukemia (CLL), and rarely in chronic myeloid leukemia (CML), which can be indicative for blast transformation.The diagnosis of leukemia cutis is usually achieved by histological study and immunophenotyping.Currently, there is no specific treatment for leukemia cutis, and cutaneous eruption usually resolves following treatment of underlying leukemia.To our knowledge, hyperpigmented patches secondary to leukemia cutis are rarely described in the literature. Dermatologists could have an important role in diagnosis of internal diseases including leukemia. Postponing the diagnosis of leukemia cutis means delaying the diagnosis of the underlying leukemia, which lead to poor prognosis. Early diagnosis of leukemia cutis can lead to better outcomes and may direct to an underlying malignancy.NN was involved in the diagnosis and management of the patients and has been responsible for the clinical part of the manuscript. ZAK reported the result of histopathological evaluation. NN, RD, and AK did literature review and drafted the manuscript. NN was responsible for final editing of the manuscript and coordinated the study. All authors have read and approved the final manuscript.This research did not receive any specific grant from funding agencies in the public, commercial, or not\u2010for\u2010profit sectors.The authors have no conflicts of interest to declare.Written informed consent was obtained from the patient for publication of this case report and accompanying images."}
{"text": "This article  has beenPLOS Genetics Editors issue this Expression of Concern.PLOS will be investigating these concerns in accordance with COPE guidance and journal policies. Meanwhile, the"}
{"text": "Retraction Note: BMC Pediatrics 22, 139 (2022)https://doi.org/10.1186/s12887-022-03210-8The authors have retracted this paper because it has been previously published by an overlapping author group . The aut"}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors\u2019 attention by a concerned reader that the western blotting data shown in Figs. 3F, 4A and 5A, and several of the panels shown for the cell invasion assays in Figs. 4C and 5C, were strikingly similar to data appearing in different form in other articles by different authors. Owing to the fact that the contentious data in the above article had already been published elsewhere, or were already under consideration for publication, prior to its submission to"}
{"text": "This article has been retracted: In July of 2020, the Academic Committee of Jiangsu Normal University launched an investigation into this paper and requested that the authors provide the original experimental records and data for verification. To date, however, the authors have failed to provide the requested documents. The committee has concluded that this paper displays signs of academic fraud. In light of this, the paper is retracted. The University and Oncotarget thank the Pubpeer community for raising the concerns.100227-100241. https://doi.org/10.18632/oncotarget.22151Original article: Oncotarget. 2017; 8:100227\u2013100241."}
{"text": "Secondly, in the Results section, \u2018Mutation frequency of each gene distributed in 4 biological categories\u2019 subsection, p. 2220, right-hand column, second paragraph, line 17, the sentence written here should have read as follows: \u2018The group with the positive expression of RET included 28.9% (26/90) of the patients, and 4 of these patients were defined as high expression\u2019.Subsequently to the publication of the above article, the authors have realized that a couple of clerical errors were made when writing the article, and wish to correct these errors in a corrigendum statement. First, in the Materials and methods section on p. 2216, the final sentence of the \u2018Oncology Reports for allowing them this opportunity to publish a corrigendum, and apologize to the readership of the journal for any inconvenience caused.The authors are grateful to the Editor of"}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors\u2019 attention by a concerned reader that certain of the cell migration and invasion assay data shown in Figs. 2C and 4D were strikingly similar to data appearing in different form in other articles by different authors. Owing to the fact that the contentious data in the above article had already been published elsewhere, or were already under consideration for publication, prior to its submission to"}
{"text": "There was an error in the original publication . Some wrA correction has been made to the following sections:Abstract:\u201cMost (76.6%) had BEWE (basic erosive wear examination) of 0\u20132.\u201dResults, Paragraph 3:\u201cLarge proportion of conscripts examined, 38.1%, had the first signs of erosive tooth wear (BEWE 1\u20132) visible in their dentition.\u201dDiscussion, Paragraph 3:\u201cOn the other hand, the results suggest also that the reason for third molar extraction was more often something other indication than the need for restorative treatment.\u201dIn the original publication, there was a mistake in the legend for Table 4. The correct legend appears below.Table 4. Distribution of BEWE score values.In the original publication, there was a mistake in The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "They also apologize to the readership for any inconvenience caused.The authors have examined their original data, and realize that errors were inadvertently made during the assembly of these figure parts. The authors have reassembled"}
{"text": "The authors regret that an incorrect version of 37 The peak at 531.3 eV is attributed to oxygen in absorbed water, and the binding energy at 532.2 eV is attributed to the oxygen atoms on defect atoms.37\u201d This text should read, \u201cThe binding energy at 530.1 eV and 531.3 eV corresponds to the oxygen atom coordinated with a metal atom (Sn\u2013O\u2013Sn) and (Sn\u2013O\u2013Zn),37 and the binding energy at 532.2 eV is attributed to the hydrated species O\u2013H.36\u201dThe authors regret that there was an error in the text in lines 5\u201310 in the right column on page 31987 of the original article. The text originally read, \u201cThe binding energy at 530.1 eV and 531.3 eV belongs to the oxygen atom coordinated with a metal atom (Sn\u2013O\u2013Sn) and (Sn\u2013O\u2013Zn), respectively.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "After this article  was publSpecifically, due to data labelling and missing information issues, the \u2018IAT\u2019 data reflect intra-arterial (IA) treatment rather than the more restricted treatment type of IA-thrombolysis. Further investigation of the dataset revealed that only 24 individuals in the study population received IA-thrombolysis, instead of N = 216 as was reported in [Furthermore, due to the small size of the IA-thrombolysis-positive group, the dataset is not sufficiently powered to address the research question.In light of the above concerns, the authors retract this article.All authors agree with retraction."}
{"text": "They were compound heterozygous for p.Arg1472Glu and c.3434del p.Lys1145fs\u22177. However c.3434del p.Lys1145fs\u22177 was noted as p.Leu1145fs\u22177 in Table\u00a0S1 and the supplemental text. This has now been corrected, and the authors regret the error."}
{"text": "Aging Cell, 2021;20:e13343. https://doi.org/10.1111/acel.13343Fei Han, Li Yin, Xiao Jiang, Xi Zhang, Ning Zhang, Jun\u2010tang Yang, Wei\u2010ming Ouyang, Xiang\u2010lin Hao, Wen\u2010bin Liu, Yong\u2010sheng Huang, Hong\u2010qiang Chen, Fei Gao, Zhong\u2010tai Li, Qiao\u2010nan Guo, Jia Cao, Jin\u2010yi Liu, Foxl2\u201d and \u201cRec8\u201d has been mislabelled with an opposite place in the histograms of quantitative PCR in Figure 5(b).In the published version of Han, F., et al. (2021), the authors noticed that the two genes \u201cThe corrected figure is shown below.The authors apologize for this error."}
{"text": "In the published publication , there w7 Department of Food and Nutrition, Faculty of Human Sciences and Design, King Abdulaziz University, Jeddah 21589, Saudi ArabiaThe authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "Retraction Note: J Exp Clin Cancer Res 39, 116 (2020)https://doi.org/10.1186/s13046-020-01606-xWithin Figure 3D, the panels (OS-RC-2 vs sh-CCDC50#1) and (OS-RC-2 vs sh-CCDC50#2) overlap.Figure 3H contained a panel (CCDC50-S vs whole) with missing sections within the image.An incorrect panel (OS-RC-2 vs sh-HnRNP A1+CCDC50-FL) was provided for supplementary figure 5B.The Editor-in-Chief has retracted this article because of the following concerns:The data reported in this article are therefore unreliable.Guoliang Sun and Hua Xu agree to this retraction. Hui Zhou has agreed to this retraction but not to the wording of this retraction notice. Ke Chen, Jin Zeng, Yangjun Zhang, Libin Yan, Weimin Yao, Junhui Hu, Tao Wang, Jinchun Xing, Kefeng Xiao, Lily Wu and Zhangqun Ye have not responded to any correspondence from the publisher about this retraction."}
{"text": "Computational Intelligence and Neuroscience has retracted the article titled \u201cTargeting Inhibition of Notch1 Signaling Pathway on the Study of Human Gastric Cancer Stem Cells with Chemosensitization [Following an investigation conducted by the Hindawi Research Integrity team , signifi"}
{"text": "A. Rogers  The authors regret the omission of the following conflict of interest statement.Dr Martin J. T. Reaney is the founder of, and has an equity interest in, Prairie Tide Diversified Inc. . Dr Youn Young Shim is a Market Consultant for PTD in Korea. The terms of this arrangement have been reviewed and approved by the University of Saskatchewan in accordance with its conflict of interest policies.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Xenopus laevis  determined from samples purified from frozen human plasma . The auts laevis . In thess laevis A and B as laevis C. FurtheApproximately 75% of A2M molecules in the samples were not native according to the authors, and this percentage increases if the 7O7M and 7O7L structures are also nonnative. In contrast, the typical percentage of nonnative A2M in circulation is less than 1% , as nonn"}
{"text": "Retraction Note: J Exp Clin Cancer Res 37, 49 (2018)https://doi.org/10.1186/s13046-018-0717-3Fig. 3a appears to overlap with Fig. 4a in ;Fig. 7g Cyclin D1 lanes 3 and 4 appear highly similar to Fig. 9d E-cadherin lanes 2 and 3 in [The Editor-in-Chief has retracted this article at the corresponding author's request. After publication, the authors became aware that data from other projects were included in the figures, resulting in image overlap between this article and previous publications from other authors. Specifically:Additionally, parts of images in Figs. 2d, 3a, 7g and 8f have subsequently been used in [The authors have therefore lost confidence in the data presented in this article.Author Kangsheng Tu has stated on behalf of all co-authors that they agree to this retraction."}
{"text": "Scientific Reportshttps://doi.org/10.1038/s41598-020-77280-y, published online 20 November 2020Retraction of: The Editors have retracted this Article. Following publication, concerns were raised about the rationale for the approach presented and the underlying reasoning. A post-publication review of the authors' mathematical arguments revealed a lack of clarity in the terms presented and inferences that are not adequately justified. The Editors therefore no longer have confidence in the conclusions presented.Muhammad Aslam does not agree to this retraction."}
{"text": "The authors regret their oversight in allowing this error to be included in the published paper, and apologize to the readership for any inconvenience caused.The revised version of"}
{"text": "Retraction: Cancer Cell Int (2020) 20:465 10.1186/s12935-020-01493-4The Editors in Chief have retracted this article. After publication it was noted that there were irregularities in Figs.\u00a03I and 5H that have led to a loss of confidence in the integrity of the results of this article. Guan Quanlin does not agree to this retraction. None of the other authors have responded to any correspondence from the Publisher about this retraction."}
{"text": "Journal of Healthcare Engineering has retracted the article titled \u201cThe Efficacy of Hydroxychloroquine Combined with Huangqi Tablets in the Treatment of Diabetic Nephropathy\u201d [ropathy\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifiThe authors do not agree with the retraction."}
{"text": "Computational Intelligence and Neuroscience has retracted the article titled \u201cEffects of Incontro, Alleanza, Responsabilita, Autonomia Intervention Model Combined with Orem Self-Care Model and the Use of Smart Wearable Devices on Perceived Stress and Self-Efficacy in Patients after Total Hip Arthroplasty\u201d [oplasty\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifiThe authors do not agree to the retraction."}
{"text": "The dexamethasone concentration was stated 10\u00a0\u03bcM while it should be 1\u00a0\u03bcM. The correct sentence should read as follows: \u201cAdipocytic differentiation was performed during 6\u00a0days using a differentiation cocktail containing dexamethasone , insulin , and isobutylmethylxanthine .\u201dThe authors state that the correction does not affect the results and conclusions of the paper."}
{"text": "Computational Intelligence and Neuroscience has retracted the article titled \u201cTanshinone Protects against Spinal Cord Ischemia-Reperfusion Injury by Inhibiting JNK Activity\u201d [ctivity\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifi"}
{"text": "Due to an Editorial Office error during processing, a number of male and female symbols were incorrectly shown in the pdf version of the manuscript . In partA correction has been made to Abstract, Section 3: paragraph 1, Table 1 (cell in first line and third column), Section 3.2: paragraph 1, Section 3.3.1: paragraph 1, Table 3 , Section 4.4: paragraph 2.The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors\u2019 attention by a concerned reader that Figs. 3, 5, 6, 7 and 9 in this paper all contained anomalous features that could not readily be explained by chance alone or through the coincidental placement of data. Consequently, the Editor of"}
{"text": "Retraction Note: Arthritis Res Ther 15, R120 (2013)https://doi.org/10.1186/ar4300Partial image overlap in Fig 3A and C;Concerns about band similarity within Western blots in Figs 5A,B and 6A,B;The actin bands in 5B appear very similar to the ones published earlier in Fig. 5B in  by the sThe Editors in Chief have retracted this article. After publication, Fig 2 was corrected because images in it had been mislabelled . HoweverThe authors were unable to produce raw data on request. The Editors have lost confidence in the integrity of the data in this article. None of the authors agree to this retraction."}
{"text": "Computational and Mathematical Methods in Medicine has retracted the article titled \u201cAnalysis of Clinical Effect after Treatment of Patients with Femoral Neck Fracture Using Total or Hemihip Arthroplasty\u201d [oplasty\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifiThe authors do not agree to the retraction."}
{"text": "Correction: Mol Cancer 18, 82 (2019)https://doi.org/10.1186/s12943-019-1016-0C. We inadvertently used an image for p62 in \u2018GBC-SD/Dox Lv-shRNA+Dox\u2019 from the original images for ATG5 in \u2018GBC-SD/Dox Lv-control+Dox\u2019 as we assembled Fig. 8C. We confirm that the mistake would not affect the results or conclusions of the paper. The image of p62 in \u2018GBC-SD/Dox Lv-shRNA+Dox\u2019 has now been replaced with the correct one.In the originally published version of this article , after r8"}
{"text": "Oxidative Medicine and Cellular Longevity has retracted the article titled \u201cLATS2 Deletion Attenuates Myocardial Ischemia-Reperfusion Injury by Promoting Mitochondrial Biogenesis\u201d [genesis\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifiThe authors do not agree to the retraction."}
{"text": "Computational Intelligence and Neuroscience has retracted the article titled \u201cSIRT2-KLF4 Interactions are Critical for Myeloma Survival and Migration\u201d [gration\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifi"}
{"text": "Retraction note to: Mol Cancer 16, 110 (2017)10.1186/s12943-017-0677-9.The Editor-in-Chief has retracted this article. After publication, concerns were raised regarding partial image overlap in Figs.1, 2 and 5\u20137. The Editor-in-Chief therefore no longer has confidence in the presented data.Yunhui Liu has stated on behalf of all co-authors that they do not agree to this retraction."}
{"text": "Open Biol.\u200910, 20170247. (Published online 1 January 2017) (https://doi.org/10.1098/rsob.160247)Following an investigation, we have found that in figures 4, 5 and 6 of the manuscript, there appears to be multiple duplications, re-positioning and alterations to the western blot images. In further review of the images and the raw data supplied by the authors, we are unable to verify the conclusions of the paper or validity of the data.https://royalsocietypublishing.org/doi/10.1098/rsob.200165.The image integrity standards and policies for the journal can be found here: Open BiologyProf. Jon Pines FRS Editor-in-Chief,\u2009Open Biology Editorial Team"}
{"text": "The authors have identified some minor errors in the published version of the"}
{"text": "Scientific Data 10.1038/s41597-021-00960-5, published online 13 July 2021.Correction to: The following errors were present in the original Data DescriptorThe colours in Figure 2 on the stacked area did not correspond to the correct agricultural activities on the legend.Table S11 (supplementary information) contained incorrect numbers for pesticide production (column 8) and the total emissions (column 9)Figure S1 (supplementary information) contained incorrect numbers for pesticide production and the total emissions, and incorrect colours on the stacked area.All aspects have been corrected in the pdf and HTML versions of the paper, and the supplementary information file.Updated supplementary file"}
{"text": "J Cancer 2022; 13(6):1895-1904. doi:10.7150/jca.60269) has been retracted due to concerns on the originality of images. Although the authors insist on the authenticity and repeatability of their data, the editors decided to withdraw this article. The authors have been contacted and they expressed apology to the readers for any negligence and mistake in this paper.This article (MiR-211-5p Inhibits the Biological Behaviors of Colorectal Cancer via SPARC-Related Growth Factor Pathways."}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors\u2019 attention by a concerned reader that certain of the cell migration and invasion assay data shown in Figs. 2D and 4D, and the western blotting data shown in Fig. 3C were strikingly similar to data appearing in different form in other articles written by different authors who were based at different institutes. Owing to the fact that the contentious data in the above article were already under consideration for publication, or had already been published elsewhere, prior to its submission to"}
{"text": "The updated figure 2b is shown below:The authors apologize for the error and any inconvenience it may have caused."}
{"text": "Sci., 2020, 11, 1216\u20131225, https://doi.org/10.1039/C9SC05586J.Correction for \u2018Expanding medicinal chemistry into 3D space: metallofragments as 3D scaffolds for fragment-based drug discovery\u2019 by Christine N. Morrison  The authors regret that in the original article, inhibitory values reported for some metallofragments were incorrect. Unfortunately, DMSO stock solutions of reportedly active ferrocene-based metallofragments were found to decompose in the presence of light, which resulted in inaccurate inhibition values. The authors maintain that the core conclusions of the paper are accurate and the utility of three-dimensional metal complexes for fragment-based drug discovery has merit.N) failed to reproduce our original inhibition results for the class A metallofragments using freshly prepared stocks, indicating a problem with the materials used in the original study.In the original article, \u2018class A\u2019 metallofragments are comprised of ferrocene derivatives . Some ofN endonuclease at an inhibitor concentration of 200 \u03bcM  inhibition against PAf 200 \u03bcM  and 2. Hf 200 \u03bcM , with thf 200 \u03bcM  not show\u03bb > 280 nm) in wet DMSO to produce a monocyclopentadienyliron cation, the anionic ligand, and free cyclopentadiene.1 Suspecting issues with photostability, we dissolved several of the ferrocenyl fragments in DMSO-d6, exposed them to ambient room light (fluorescent light bulb), and monitored stability by NMR. Indeed, photoinstability was confirmed by the observance of free cyclopentadienyl peaks appearing in the 1H NMR spectrum  proved stable in DMSO and class A metallofragments were stored as DMSO stocks at \u221280 \u00b0C, but were not consistently protected from light. As noted above, many of the derivatives in class A contain a ferrocenyl carbonyl motif. It has been previously reported that ferrocenyl ketones can undergo photoaquation  as a positive control.2 Fortunately, these experiments largely reproduced our original findings. Although several fragments showed slightly greater activity upon re-evaluation  binding data. Furthermore, the hit rate against each target is likely lower than reported, with PAN having an adjusted hit rate of \u223c28% (20/71).Based on these findings, the authors regret that the inhibitory data associated with class A metallofragments are incorrect, likely because of photodecomposition of these ferrocene derivatives. To confirm if other classes of metallofragments were correctly reported, a representative member of each class was evaluated against PAThe authors maintain that three-dimensional metallofragments represent a useful new line of inquiry for FBDD and our ongoing studies seek to further test this hypothesis. The core message of our original study \u2013 the ability of metallofragments to be useful scaffolds for FBDD that occupy hard-to-access three-dimensional chemical space \u2013 remains unchanged. However, as demonstrated by our error, the authors acknowledge that metallofragments may pose unique challenges that must be carefully considered and controlled for when using them in FBDD campaigns.The authors would like to take this opportunity to thank the readers who alerted them to the concerns regarding the inhibitory activities and allowed them to reinvestigate. Both the authors and the Royal Society of Chemistry appreciate their support.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Retraction: Journal of Translational Medicine 2008, 6:27https://doi.org/10.1186/1479-5876-6-27Two pairs of bands appear highly similar in Fig.\u00a05a\u2014MSTO C CycD1 (CTRL 3\u00a0h and 6\u00a0h) and P\u2009+\u2009C Actin (CTRL 6\u00a0h and 24\u00a0h).A number of bands appear highly similar in Fig.\u00a06b P\u2009+\u2009C Actin.Also in Fig.\u00a06b, NCI P p21 bands (CTRL 6\u00a0h and 24\u00a0h) appear highly similar to P\u2009+\u2009C p21 bands (CTRL 3\u00a0h and 6\u00a0h).All NCI Actin bands appear to be highly similar in Figs. 5a and 6b.NCI C Actin bands in Figs.\u00a05a and 6b appear to be highly similar but rotated 180 degrees, with the same bands representing different groups.In Fig.\u00a06b NCI blots, some backgrounds appear inconsistent and contain unexpected breaks or changes between bands.The Editor-in-Chief has retracted this article [1]. After publication, concerns were raised regarding potential issues in the western blot images presented in the figures. Specifically:As the article was published in 2008, the authors are unable to provide the raw data used to produce these figures. The Editor-in-Chief therefore no longer has confidence in the presented data.Alfonso Baldi does not agree to this retraction. Angela Nebbioso and Lucia Altucci have not explicitly stated whether they agree to this retraction. Simona Menegozzo has not responded to any correspondence from the editor or publisher about this retraction. The Publisher has not been able to obtain a current email address for author Alessandra Verdina, Irene Cardillo, Rossella Galati and Ada Sacchi."}
{"text": "The authors regret the omission of one of the funding bodies in the Acknowledgements: Foundation of Science and Technology Department of Jilin Province (No. 20170623027TC to JJ). The corrected list of funding bodies is shown below:This work was financially supported by the National Key R&D Program of China (No. 2017YFA0505300 to HW), NSFC , and Foundation of Science and Technology Department of Jilin Province (No. 20170623027TC to JJ).The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "In the paper"}
{"text": "Estimated CRS burden in all scenarios should be 3 times greater than indicated.The authors regret age-specific fertility rates were incorrectly applied when determining burden of congenital rubella syndrome (CRS). Annual fertility rates, averaged over 3\u00a0years, were used as rate-Corrected scales for the x-axis in Figs. 3 and 4 should be 0\u20136 (instead of 0\u20132 as depicted). Corrected scale for the y-axis in Fig. 5a should be 0\u20133 (instead of 0\u20131 as depicted), and the corrected scale for the x-axis in Fig. 5b should be 0\u201312 (instead of 0\u20134 as depicted).Fig. 3:Fig. 4:Fig. 5:The authors would like to apologise for any inconvenience caused."}
{"text": "J Cell Mol Med. 2021; 25: 2025\u20132039. doi:10.1111/jcmm.16096.Retraction: Yang, C, Gu, Z, Ding, R, et al. Long non\u2010coding RNA MEG3 silencing and microRNA\u2010214 restoration elevate osteoprotegerin expression to ameliorate osteoporosis by limiting TXNIP. wileyonlinelibrary.com) has been retracted by agreement between the authors, the journal Editor in Chief, and John Wiley and Sons Ltd. The retraction has been agreed following an investigation based on concerns raised by the authors and allegations raised by a third party. Several flaws and inconsistencies between results presented and experimental methods described were found, the editors consider the conclusions of this article to be invalid.The above article published online on 03 January 2021 in Wiley Online Library ("}
{"text": "The editors reached out to the authors to request the original data. Per journal policy, the editors, at their discretion, may request deposition of any or all original data files for examination by the reviewers and/or editors. As a result of the authors\u2019 failure to provide these data\u2014in violation of journal policy\u2014and the allegations of fraud, the editors feel that findings of the manuscript cannot be relied upon. All authors have been informed."}
{"text": "Arg and ATE1 overlooked the citation of the original work from where it was adapted [x]. The missed citation [x] is, therefore, clarified in the corrected legends (below) as reference [The authors wish to make the following corrections to the original publication . In the eference . The corThe authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "The authors also regret any inconvenience that this mistake may have caused.The corrected version of"}
{"text": "Computational and Mathematical Methods in Medicine has retracted the article titled \u201cAnalysis of Multifactor-Driven Myopia Disease Modules to Guide Personalized Treatment and Drug Development\u201d [lopment\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifiThe authors do not agree to the retraction."}
{"text": "The authors regret the error in 1 using\u03bc,\u03bd = x,y,z, fni,mj,\u03bc is the \u03bcth component of the force on vertex i belonging to particle n from vertex j belonging to particle m, Rmj,ni,\u03bd is \u03bdth component of the separation vector from the center of mass of particle n to the contact point between vertex i on particle n and vertex j on particle m. The pressure is defined as . We have verified that We calculate the Love stress tensor under periodic boundary conditionThe Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Ethics approval was required and approved for Australian study and each contributing country was responsible for ethics to collect feed intake data.The animal ethics statement was missing from this paper. The following statement should have been included:"}
{"text": "RSC Advances article due to concerns with the reliability of the data. The images in the article were screened by an image integrity expert. Images published in the article have also been published in two other papers, one by the same authors1 but another by a different set of authors.2The Royal Society of Chemistry hereby wholly retracts this The left and centre panels of Fig. 2A represent different sections of the same image. Furthermore, the same image is also duplicated in ref. RSC Advances article.The right panel in Fig. 2A and the left panel in Fig. 2B are identical to images published in ref. Given the significance of the concerns about the validity of the data, the findings presented in this paper are not reliable.Qun Liang does not agree with this retraction. The other authors were informed but have not responded to any correspondence regarding the retraction.RSC AdvancesSigned: Laura Fisher, Executive Editor, th January 2021Date: 19"}
{"text": "Computational and Mathematical Methods in Medicine has retracted the article titled \u201cProteomics reveals molecular changes in insomnia patients with more dreams\u201d [ dreams\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifiThe authors do not agree to the retraction."}
{"text": "In Figure We sincerely apologize for any confusion caused by our negligence and this unintentional error. The authors confirm that the corrections made in this erratum do not affect the original conclusions."}
{"text": "This protocol describes the different methods to collect and preserve bark and ambrosia beetles, detailing collecting tools, recording relevant data, and optimizing step-by-step methods to extract beetles from twigs, branches, bark, and trunks. It elaborates on trapping techniques, tools, lures, baits, and beetle preservation. The main rule of manual collecting is to not attempt to pry the insect out of the wood or bark, but instead, remove the wood/bark away from the beetle: gently and systematically. The main rule of trapping is that there is no general attractant; instead, attractants and traps should reflect the ecology of the targeted beetle taxa. Euwallacea fornicatus species complex has caused significant impacts to orchards and natural forests around the world [Insect sampling and insect collections are some of the most important components of entomological research and teaching. However, certain taxa, particularly small wood borers, are challenging to sample. Bark and ambrosia beetles (Coleoptera: Curculionidae: Scolytinae and Platypodinae) are some of the smallest and most common insects in natural, urban, and commercial forests. While the vast majority breed in dead or dying tissues and are harmless, some species have caused devastating damage across within both native and introduced range. Just in the last decades, more than 300 million redbay trees have been killed by laurel wilt , millionhe world .Bark beetle sampling is an essential part of integrated management programs, including beetle surveillance and monitoring by government agencies. For example, the Cooperative Agricultural Pest Survey (CAPS) by the USDA APHIS, which conducts national and state surveys, together with the Forest Service\u2019s Early Detection and Rapid Response program (EDRR), are responsible for post-introduction detection of pests . HoweverContemporary biobanks are increasingly focused on collecting and storing the specimen with its context . In the Bark and ambrosia beetle species are distinguished by small and subtle morphological differences \u201315. TherAlso of increasing importance has been the collecting of high quality samples for DNA studies. Advancements in molecular biology techniques have benefited numerous research fields related to forest health, including phylogenetics and systematics, invasion ecology, and forest pest diagnostics , 17. MolDespite extensive treatment of wood boring insects in literature on collecting and preserving insects, little is mentioned regarding manual extraction from wood samples . SuccessHere we present a protocol to collect bark and ambrosia beetles, with step-by-step guidelines to obtain high quality samples. It describes the different methods to collect and preserve bark ambrosia beetles, detailing collecting tools, relevant data, and optimized methods to extract beetles from twigs, branches, bark, and trunks. Moreover, it elaborates on trapping techniques, tools, lures, baits, and beetle preservation.https://www.protocols.io/workspaces/protocols-bark-beetle-mycobiome). Bark Beetle Mycobiome is a global research community reinvigorating the science of bark beetle-fungus symbiosis [This protocol is part of a repository hosted on Protocols.io, as part of the public workspace \u2018Bark Beetle Mycobiome (BBM) research coordination network\u2019 Click here for additional data file."}
{"text": "The authors wish to make the following corrections to this paper :E was mistakenly referred to as in emulsion form, as below:AS01E) [40]. The adjuvant in this vaccine, AS01, consists of a mixture of the TLR4 ligand, MPLA, together with the saponin fraction QS21 in a liposomal or emulsion formulation [41].One of the most advanced subunit vaccines, M72:AS01, was recently shown to have 54% efficacy in HIV-negative individuals with latent TB when administered intramuscularly in emulsion form  [40]. The adjuvant in this vaccine, AS01, consists of a mixture of the TLR4 ligand, MPLA, together with the saponin fraction QS21 in a liposomal formulation [41].One of the most advanced subunit vaccines, M72:AS01, was recently shown to have 54% efficacy in HIV-negative individuals with latent TB when administered intramuscularly (M72:AS01The authors would like to apologize for any inconvenience caused to the readers by these changes and state that the scientific conclusions are unaffected. The original publication has also been updated."}
{"text": "DOI: 10.1039/C5RA11545KRetraction of \u2018Facile fabrication of water-dispersible AgInS They informed us that \u201cRijun Gui has confirmed that he independently completed the experimental research before he joined Qingdao University. Without their knowledge and prior notice, he signed the names of irrelevant researchers  in his paper and added the Funding numbers of the irrelevant researchers in his papers without authorization. Rijun Gui confirmed that these irrelevant researchers did not participate in experimental researches reported in his paper and they did not provide financial support. They have no contribution to the paper.\u201d They concluded that \u201cthe names of the irrelevant researchers without contribution are required to be deleted from the authorship of the paper, and their funding numbers without providing financial support are required to be deleted from the \u201cAcknowledgements\u201d.\u201d The corrected authorship list and affiliations for this paper are as follows:aRijun Gui*aSchool of Chemistry and Chemical Engineering, Shanghai Jiao Tong University, Shanghai 200240, P. R. China, email: guirijun@163.comThe corrected Acknowledgements for this paper are as follows:This work was financially supported by the Postdoctoral Science Foundation of Shanghai (13R21413800).RSC Advances article due to concerns with the reliability of the data in the published article.(2) The Royal Society of Chemistry hereby wholly retracts this The TEM image in Fig. 2a contains duplications of the same particles within the image, which indicates that it has been manipulated.et al., but representing different materials.1The TEM image in Fig. 2c duplicates data from another publication by Tan et al., but representing different materials.2The TEM image in Fig. 2d duplicates data from another publication by Tan Given the number and significance of the concerns about the validity of the data, the findings presented in this paper are no longer reliable.Rijun Gui requested to retract this article due to the incorrect authorship, but opposes the wording in this retraction notice.RSC AdvancesSigned: Laura Fisher, Executive Editor, st September 2020Date: 21"}
{"text": "DOI: 10.1039/D1RA05703K.Correction for \u2018Sample preparation considerations for surface and crystalline properties and ecotoxicity of bare and silica-coated magnetite nanoparticles\u2019 by Lyubov Bondarenko  The authors regret that the name of one of the authors  was shown incorrectly in the original article. The corrected author list is as shown above.35 or oxygen-sensitive nanoparticles (NPs) such as iron oxides.\u201d This sentence should read, \u201cNot all of these methods can be applied to \u201csoft\u201d nanoparticles 35 or oxygen-sensitive nanoparticles (NPs) such as iron oxides\u201d.The authors regret that there was an error in the sentence in line 28 in the right column on page 32227 of the original article. The text originally read, \u201cNot all of these methods cannot be applied to \u201csoft\u201d nanoparticles The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "All the authors agree to the publication of this Corrigendum, are grateful to the Editor of"}
{"text": "Correction to: European Journal of Nuclear Medicine and Molecular Imaging (2022) 49:1386\u20131406https://doi.org/10.1007/s00259-021-05624-5The authors regret that there is an error in their original article. They found a small mistake in the abbreviations, because the meaning of ESTRO and EORTC has been interchanged. It says:-EORTC\u2009=\u2009European Society for Radiotherapy and Oncology-ESTRO\u2009=\u2009European Organisation for Research and Treatment of CancerBut it should be:-ESTRO\u2009=\u2009European Society for Radiotherapy and Oncology-EORTC\u2009=\u2009European Organisation for Research and Treatment of Cancer"}
{"text": "Computational and Mathematical Methods in Medicine has retracted the article titled \u201cThe Construction and Development of App Application Platform for Public Information Products of Urban Grand Media in the Context of Artificial Intelligence\u201d [ligence\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifi"}
{"text": "The original version of our paper contained an error. In Figure All authors agree to the erratum and confirm that the corrections made in this erratum do not affect the original conclusions. The authors apologize for any inconvenience that the errors may have caused."}
{"text": "On the first publication of MCO273, the authors noted that images of SGC\u20107901 group in Figure"}
{"text": "The authors wish to make the following correction to this paper :In the original publication, there was a mistake in The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "Retraction Note: BMC Pregnancy Childbirth 18, 351 (2018)https://doi.org/10.1186/s12884-018-1989-5The Editor has retracted this article. After publication, concerns were raised around p-values in Table 2, as well as the sample size and dates when the study was conducted. The authors provided raw data which did not fully correspond to the data presented in the article. They also proposed to correct the discrepancies, but some of the proposed corrections were also found to contain errors. The Editor has, therefore, lost confidence in the validity of the paper's findings. None of the authors agree to this retraction."}
{"text": "RSC Advances article due to concerns with the reliability of the data. The images in the article were screened by an image integrity expert. All the western blot bands have a very regular, oval shape that are unlikely to be genuine. Furthermore, the western blots and many other features of the article were found to be unexpectedly similar to western blots and features in a number of other papers with no overlapping authors.The Royal Society of Chemistry hereby wholly retracts this The authors were asked to provide the raw data for this article, but did not respond. Given the significance of the concerns about the validity of the data, and the lack of raw data, the findings presented in this paper are not reliable.The authors have been informed but have not responded to any correspondence regarding the retraction.RSC AdvancesSigned: Laura Fisher, Executive Editor, th January 2021Date: 15"}
{"text": "Jadhav,  The authors regret the omission of the following conflict of interest statement.Dr Martin J. T. Reaney is the founder of, and has an equity interest in, Prairie Tide Diversified Inc. . Dr Youn Young Shim is a Market Consultant for PTD in Korea. The terms of this arrangement have been reviewed and approved by the University of Saskatchewan in accordance with its conflict of interest policies.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "RSC Advances paper and concerns about discrepancies in the data and results presented in the article.The Royal Society of Chemistry has been contacted by the President of the Amity Science Technology & Innovation Foundation, Amity University Uttar Pradesh regarding an investigation into the authorship of this (1) The investigation by Amity University Uttar Pradesh has concluded that Nitesh Malhotra and Nidhi Chauhan should not have been included as co-authors because they only made a minimal contribution to the study. Their contributions were that Nitesh Malhotra provided the leviteracetum drug and Nidhi Chauhan provided the multiwalled carbon nanotubes.Aside from the institutional investigation, the corresponding author has also confirmed to us that C. S. Pundir should not have been included as a co-author as their contribution was to check the language in the manuscript.The contributions of Nitesh Malhotra, Nidhi Chauhan and C. S. Pundir should have been acknowledged in the article, but did not justify authorship.The corrected authorship list and affiliation for this paper are as follows:aJagriti Narang*aAmity Institute of Nanotechnology, AMITY University, Noida, India. E-mail: jags_biotech@yahoo.co.in; Tel: +9811792572.RSC Advances article due to concerns with the reliability of the data in the published article.(2) I, Jagriti Narang, the corresponding author hereby wholly retract this The TEM images in Fig. 1a and SEM images in Fig. 2b and c each contain repetitions of a number of distinct shapes within the images.The XRD data in Fig. 1b contains repetitions of the same peaks within the traces. The peak at 11\u00b0 in the GNF trace has been duplicated in the MWCNT/GNF trace at 11 and 24\u00b0 and in the MWCNT trace at 24\u00b0. In addition, the peak at 45\u00b0 in the MWCNT trace has been duplicated at 78\u00b0 in the MWCNT trace and at 70\u00b0 and 78\u00b0 in the FTO trace.The investigation by Amity University Uttar Pradesh has recommended that the paper should be retracted.Signed: Jagriti Narang.RSC Advances.Retraction endorsed by Andrew Shore, Executive Editor,"}
{"text": "Nature Communications 10.1038/s41467-019-13388-8, published online 16 December 2019Retraction of: The authors are retracting the Article due to several issues with figure assembly and data integrity. Nanoparticles appear to be duplicated within the same image in Figure 1a. In addition, there are unexplained anomalies in Supplementary Figures 1, 2, 24, and 36. These issues undermine confidence in the integrity of the study and its conclusions. All authors agree with this retraction."}
{"text": "We thank Tsai and Liu  for theiTo say that the study should be more quantitative negates that prospective sleep logging is both quantitative and the consensus tool for the field . What maThis seems a pertinent time to remind the authors of the letter  that the"}
{"text": "In the original publication , there wThe legend for Table 1: Summary of descriptive statistics in neuropathologically confirmed AD patients, stratified by APOE4 status (E4 (\u2212) = 0 APOE4 alleles, E4 = 1 APOE4 allele, E44 = 2 APOE4 alleles).In the original publication, there was an error in the location of the legend for Figure 2. The legend was incorrectly placed under the legend for Table 1. The correct legend appears below. p = 0.03).The legend for Figure 2: Graphical depiction of the average age of female APOE4 non-carriers and female APOE4 homozygotes, illustrating the significant difference between the two groups. On average, female APOE4 homozygotes were significantly younger than female APOE4 non-carriers  cohort, examining the relationship between APOE4 status and the presence of psychosis across sex while adjusting for age, education and MMSE.There was an error in the original publication. The NACC dataset that was utilized was incorrectly referred to as the Unified Data Set (UDS). The correct name for the dataset that was utilized is the Uniform Data Set (UDS).A correction has been made to Section 2.1. Data Source: Two datasets were utilized: the Uniform Data Set (UDS) and the Neuropathology Data Set (NP).There was an error in the original publication. The paragraph indicated under Funding should be listed under Acknowledgments instead.The following should be under Acknowledgments: The authors acknowledge NACC and the SMH Foundation Heather and Eric Donnelly endowment for their support of this project. The NACC database is funded by NIA/NIH Grant U24 AG072122. NACC data are contributed by the NIA-funded ADRCs: P30 AG062429 , P30 AG066468 , P30 AG062421 , P30 AG066509 , P30 AG066514 , P30 AG066530 , P30 AG066507 , P30 AG066444 , P30 AG066518 , P30 AG066512 , P30 AG066462 , P30 AG072979 , P30 AG072972 , P30 AG072976 , P30 AG072975 , P30 AG072978 , P30 AG072977 , P30 AG066519 , P30 AG062677 , P30 AG079280 , P30 AG062422 , P30 AG066511 , P30 AG072946 , P30 AG062715 , P30 AG072973 , P30 AG066506 , P30 AG066508 , P30 AG066515 , P30 AG072947 , P30 AG072931 , P30 AG066546 , P20 AG068024 , P20 AG068053 , P20 AG068077 , P20 AG068082 , P30 AG072958 , P30 AG072959 . Data from the Alzheimer\u2019s Disease Genetic Consortium (ADGC) was used, NIA/NIH Grant U01 AG032984.The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "Journal of Healthcare Engineering has retracted the article titled \u201cAnalysis of the miRNA-mRNA Regulatory Network Reveals the Biomarker Genes in the Progression of Myocardial Ischemic Reperfusion\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifi"}
{"text": "There are many reasons to reform the Stability and Growth Pact, but that reform is no panacea. This is because the euro area periphery has increasingly entered a debt conundrum."}
{"text": "Retraction Note: BMC Cancer 19, 530 (2019)https://doi.org/10.1186/s12885-019-5750-xIn Figure 1A and 1C it appears that the Western blot quantification doesn't match the images presented. In addition, the label for the y axis does not match the Western blot label it is supposed to quantify in 1A.In Figure 6 it appears that the image used for Anti-GFP in Figure 6B and 6C are the same.The Editor has retracted this article. Concerns have been raised about a number of figures in this article:The authors stated that the figures were obtained through a commercial lab hired to perform some of the experiments for this study. The authors didn't receive the raw data and couldn't share it with the journal. They were also unable to reproduce the findings in their own follow up experiments. The Editor therefore no longer has confidence in the integrity of the data in this article.Author Guoying Zhang has stated on behalf of all co-authors that they agree to this retraction."}
{"text": "K. Tang et al.35\u201d. The citation to ref. 41\u201343 before the conclusions should be changed to ref. 41 and 42.The authors regret that there were some errors in the references in the original article. On page 6197, the text \u201cAlternatively, a method employed by G. Y. Yang In the references section, the original ref. 35 should be deleted, and the original ref. 41 should be renumbered as ref. 35. The original ref. 42 and 43 should also be renumbered as ref. 41 and 42, respectively.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "The authors regret the errors made in The correct figure is as follows:The authors would like to apologise for this oversight and any inconvenience caused."}
{"text": "Journal of Healthcare Engineering has retracted the article titled \u201cInfluence of Internet Language Violence on Young Students' Mental Health and Intervention Countermeasures\u201d [easures\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifiThe authors do not agree to the retraction."}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors\u2019 attention by a concerned reader that certain of the cell migration and invasion assay data shown in Figs. 2C and 4C were strikingly similar to data appearing in different form in other articles by different authors. Owing to the fact that the contentious data in the above article had already been published elsewhere, or were already under consideration for publication, prior to its submission to"}
{"text": "The authors would like to make two corrections to the text:MethodsThe scoring of the fourth item was reversed, and thus a higher score signified feeling less overwhelmed.All questions were answered on a four-point scale ranging from 0 (strongly disagree) to 3 (strongly agree). Table 6with reversed scoring of the fourth item (N\u00a0=\u00a010)Outcomes on the study-specific questionnaire ranging from 0 (strongly disagree) to 3 (strongly agree) points, The authors sincerely apologise for the errors."}
{"text": "The final entry for Table 1 relating to Sample C-4 in the published paper showed an incorrect entry for the column [POSSMA]\u2009:\u2009[AZOMA]\u2009:\u2009[DMAEMA]\u2009:\u2009[CDB]\u2009:\u2009[AIBN]; this should read 12\u2009:\u200950\u2009:\u2009100\u2009:\u20090\u2009:\u20090.20.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Thrips hawaiiensis (Morgan)) change the stereochemical configuration of 1-phenylethanol emitted from tea (Camellia sinensis) flowers\u2019 by Ying Zhou et al., RSC Adv., 2017, 7, 32336\u201332343. DOI: 10.1039/C7RA03219F.Correction for \u2018Insects ( The authors regret that incorrect versions of The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Journal of Healthcare Engineering has retracted the article titled \u201cApplication Evaluation of High-Flow Humidified Oxygen in Patients with Respiratory Failure after General Anesthesia Extubation for Multiple Injuries\u201d [njuries\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifi"}
{"text": "Chem., 2022, 13, 817\u2013821, https://doi.org/10.1039/D2MD00085G.Correction for \u2018Thiamine analogues as inhibitors of pyruvate dehydrogenase and discovery of a thiamine analogue with non-thiamine related antiplasmodial activity\u2019 by Alex H. Y. Chan  Chinese patent ZL201510672520.1  should have been cited as this describes the synthesis of compounds The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Journal of Healthcare Engineering has retracted the article titled \u201cStudy on the Effect of Combination of Prednisone and Vitamin D in the Treatment of Primary Nephrotic Syndrome in Children\u201d [hildren\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifiThe authors do not agree to the retraction."}
{"text": "Applied Surface Science.1 Although different data and results are reported in each article, the Applied Surface Science article should have been cited in this RSC Advances article.The Royal Society of Chemistry has been made aware of a closely related paper, published by the authors at nearly the same time in The authors have been contacted but have not responded to our communication.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "This article has been retracted: Oncotarget has completed its investigation of this paper. We found that Figures 2C, 2E, 5C, 5D, 6E, and Table 1 contain similarities with data appearing in other articles by different authors. The data had already been published elsewhere, or were already under consideration for publication prior to submission to Oncotarget. During our long period of communication with the authors, we received a request from corresponding author Jin He to retract the paper. As of this writing, Oncotarget has not received signed documentation from all authors acknowledging the retraction. Oncotarget has also notified the affiliated institution regarding this retraction.91530-91541. https://doi.org/10.18632/oncotarget.21069Original article: Oncotarget. 2017; 8:91530\u201391541."}
{"text": "Retraction Note: BMC Pregnancy Childbirth 17, 160 (2017)https://doi.org/10.1186/s12884-017-1349-xThe Editor has retracted this article as the authors were unable to provide evidence that they have received ethics approval for the full duration of this study in the hospital setting and were unable to provide evidence that they have received ethics approval for the parts of the study done in private settings. Abd Elaziz A. El Refaeey and Abdelhady Zaied do not agree to this retraction. Hosam Abdelfattah, Alaa Mosbah, Anas M. Gamal, Emad Fayla, Waleed Refaie, Rafik I. Barakat, Amal K. Seleem and Mohammed Maher have not responded to any correspondence from the editor/publisher about this retraction."}
{"text": "In the original publication , there wThere was an error in the original publication . We had Section 3, Paragraph 1:Half reported that it was not a typical night out for them.Section 3, Paragraph 2:For male participants, the preference for late-closing bars was associated with the following: the youngest age group (age 18\u201321); clerical occupations (compared to \u2018other\u2019); and the survey occurring on Friday night.Section 4, Paragraph 5:Furthermore, half of participants were not on a typical night out for them so may have been drinking at venues they did not typically frequent and/or may have gone home earlier or stayed out later than usual.The authors apologise for any inconvenience caused and state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "Given that statistics may be more or less adequate, the appropriate use of models and their output can contribute to effective preventive, diagnostic and treatment strategies, however, misuse or misinterpretation of their output can mislead decision-making. In the early'90, to summarize probabilistic data and provide practical guidance to clinical decision making, we sought the birth of the evidence-based model and the diffusion of guidelines developed accordingly . Besides, it should also be pointed out that in clinical practice a systematic assessment of health outcomes with post-study probability tests is needed to confirm the intervention effectiveness , and a continuous on-going refinement.Finally, when facing Both authors listed have made a substantial, direct, and intellectual contribution to the work and approved it for publication.The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher."}
{"text": "In the original publication , there wAdditionally, we made the following changes in the text of the manuscript according to the corrected 2:MoS2 (0.1:1.0) hybrid nanolubricants produce even less surface damage with the smoothest worn surface and fewest grooves in a more random pattern.\u201d\u201cIn marked contrast, the SiOwith the one below:2:MoS2 (0.1:1.0) hybrid nanolubricants produce even less surface damage with wear debris and fewest grooves in a more random pattern.\u201d\u201cIn marked contrast, the SiOIn Section 3.4, we replaced the following sentence:The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "Cell Discovery (2023) 9:5Correction to: 10.1038/s41421-022-00500-4 published online 11 January 2023During the production, we mislabeled all the authors as corresponding authors. The corrected one appeared as below. We apologize for any inconvenience that it may have caused.Correspondence: Fuchou Tang (tangfuchou@pku.edu.cn)"}
{"text": "In an articleThe authors apologize for the error."}
{"text": "The correct affiliation is shown here.The authors regret that affiliation \u03c7 = 0.5 wt% is 33.8\u2026\u201d incorrect units were given. The corrected sentence is as follows: For instance, PF of the sample with \u03c7 = 0.5 wt% is 33.8 \u03bcW cm\u22121 K\u22122 at 482 K, which is \u223c33% larger than that of the BST matrix (25.5 \u03bcW cm\u22121 K\u22122).In the sentence beginning \u201cFor instance, PF of the sample with \u03c7 = 0.5 wt%, \u03ba decreases from 1.10\u2026\u201d incorrect units were given. The corrected sentence is as follows: For instance, as to the sample with \u03c7 = 0.5 wt%, \u03ba decreases from 1.10 to 0.99 W m\u22121 K\u22121 at 482 K (a \u223c10% decline).In the sentence beginning \u201cFor instance, as to the sample with The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Correction to: Trials 23, 162 (2022)https://doi.org/10.1186/s13063-022-06083-5Following the publication of the original article , we wereOriginally published sections:Funding: \u201cThe Wushu Research Institute of the State Sports General Administration (WSH2018A005).Authors\u2019 contributions: \u201cLYK was involved in the conception and design of the research. LYH obtained ethics approval. LYH drafted the manuscript. All authors edited and revised the manuscript. All authors approved the final version of the manuscript.\u201dCorrected sections:Funding: \u201cFund Project: Zhejiang Provincial Department of Education College Teacher Professional Development Project (FX2018064); Zhejiang Provincial Department of Education University Scientific Research Program Project (Y201533645)\u201dAuthors\u2019 contributions: \u201cLXW was involved in the conception and design of the research. LXW obtained ethics approval. LYH drafted the manuscript. All authors edited and revised the manuscript. All authors approved the final version of the manuscript.\u201dThe original article has been corrected."}
{"text": "J. R. Soc. Interface14, 20170247. (Published online 31 May 2022) (https://doi.org/10.1098/rsif.2017.0247)This corrigendum corrects the record and includes Mahesh M. Bandi and Madhusudhan Venkadesan as corresponding authors for the article.bandi@oist.jpm.venkadesan@yale.edushreyas.mandre@warwick.ac.uk"}
{"text": "Lastly, the authors apologize to the readership for any inconvenience these errors may have caused.The corrected versions of"}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors\u2019 attention by a concerned reader that the western blotting data shown in Figs. 3D, 4B and 5A, and several of the panels shown for the cell invasion assays in Figs. 2C and 5C, were strikingly similar to data appearing in different form in other articles by different authors. Owing to the fact that the contentious data in the above article had already been published elsewhere, or were already under consideration for publication, prior to its submission to"}
{"text": "Communications Biology 10.1038/s42003-022-03327-7, published online 11 April 2022.Correction to: This Correction added Andrey Andreev and Kevin Keomanee-Dizon as equally contributing authors together with Thai V. Truong, Daniel B. Holland, Sara Madaan, which was incorrect. This has now been reverted back to the original list of contributing authors."}
{"text": "The authors have requested that this preprint be removed from Research Square."}
{"text": "Phil. Trans. R. Soc. B378, 20210070. (Published online 14 November 2022). (https://doi.org/10.1098/rstb.2021.0070)In the original version of this article the authors' affiliations were listed incorrectly.This has now been corrected on the publisher's website to the following:1,\u2020, Deo D. Shirima2,11, Olivier Villemaire-C\u00f4t\u00e93, Philip J. Platts1,4,5, Sarah J. Knight1, Robin Loveridge1,6, Hamidu Seki1, Catherine E. Waite10, Pantaleo K. T. Munishi2, Herman Lyatuu11, Blanca Bernal8, Marion Pfeifer9 and Andrew R. Marshall1,10,11,12,\u2020Abigail R. Wills\u2020These authors contributed equally to this manuscript."}
{"text": "The Royal Society of Chemistry hereby wholly retracts this RSC Advances article due to concerns with the reliability of the data. The Editor has been contacted by Link\u00f6ping University, Sweden regarding an investigation by the National Board for Assessment of Research Misconduct (NPOF) which has concluded that this RSC Advances article contains fabricated XRD data in Fig 2 and 13b.The authors do not agree with NPOF\u2019s ruling of research misconduct.A. Habibi-Yangjeh stated that this research has been carried out in Link\u00f6ping University, Sweden, under the supervision of Dr Omer Nur, during the sabbatical leave of the first author. In this paper, the contribution of A. Habibi-Yangjeh was discussion about the photocatalysis results and editing of the proof, and he has not contributed in XRD analyses, which are the subject of this retraction.The other authors have not responded to correspondence regarding this retraction.Signed: Laura Fisher, Executive Editor, RSC AdvancesDate: 16th February 2023"}
{"text": "In the original publication , there wThe authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "Journal of Healthcare Engineering has retracted the article titled \u201cApplication Value of Real-Time Ultrasonic Elastograph with Serum Human Epididymis Protein 4, Interleukin-33, and Carbohydrate Antigen 153 in Diagnosis of Early Cervical Cancer\u201d [Following an investigation conducted by the Hindawi Research Integrity team , signifi"}
{"text": "Following publication, concerns were raised regarding the validity of the data in the article. The authors were unable to provide the complete raw dataset or a satisfactory explanation during the investigation, which was conducted in accordance with Frontiers\u2019 policies. Given the concerns and the fact that raw data were only partially provided, the editors no longer have confidence in the findings presented in the article.This retraction was approved by the Chief Editors of Frontiers in Cell and Developmental Biology and the Editor-in-Chief of Frontiers. The authors did contact the Editorial office spontaneously to rectify the scientific record, and thus agree to the retraction."}
{"text": "Retraction Note: Mol Cancer 13, 69 (2014)https://doi.org/10.1186/1476-4598-13-69In Fig. 1D, the NCI and MSTO EXE group images appear highly similar; the authors have confirmed that the original image for MSTO EXE has been replaced in the figure.The NCI and Met-5A images in Fig. 1D are also highly similar to HFF and Met5A in Fig. 2 in\u00a0[Fig. 1G EXE (48) MSTO and CNTR (0) NCI images appear highly similar to those in Fig. 2D (48) MSTO and NCI, respectively (rotated).In Fig. 2B, the western blot images are composites of multiple gels without clear indication of image cropping or editing.The Editor-in-Chief has retracted this article. After publication, concerns were raised regarding the cell and western blot images presented in the figures. Specifically:Additionally, the ethics approval information provided by the authors upon the Journal's request does not match the details stated in the Methods section.The Editor-in-Chief therefore no longer has confidence in the presented data.Rosella Galati does not agree to this retraction. The Publisher has not been able to obtain a current email address for Barbara Nuvoli, Sabrina Germoni, Carlotta Morosetti, Raffaela Santoro, Giancarlo Cortese, Serena Masi and Iole Cordone."}
{"text": "Journal of Healthcare Engineering has retracted the article titled \u201cTooth Loss and the Incidence of Ischemic Stroke and Transient Ischemic Attack: A Systematic Review and Meta-Analysis\u201d [nalysis\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifi"}
{"text": "RSC Advances article due to concerns with the reliability of the data. Images published in Fig. 2 and 5 of the article have been duplicated in another article.1 There are no common authors between the papers.The Royal Society of Chemistry hereby wholly retracts this Rotated and scaled versions of the second and third tumor images in Fig. 5B of this paper are duplicated in the \u2018sh-con\u2019 panel in Fig. 6B of ref. A rotated version of the \u2018si-con/SK-MEL-2\u2019 colony formation image in Fig. 2E of this paper is duplicated in Fig. 2D (si-con/MCF-7\u2032 image) of ref. An inverted version of the \u2018si-con/A375\u2019 colony formation image in Fig. 2E of this paper is duplicated in Fig. 2D (\u2018si-PVT1#2/MDA-MB-231\u2019 image) of ref. The authors were asked to provide the raw data for this article, but did not respond. Given the significance of the concerns about the validity of the data, and the lack of raw data, the findings presented in this article are not reliable.The authors were informed but have not responded to any correspondence regarding the retraction.RSC AdvancesSigned: Laura Fisher, Executive Editor, Date: 18th August 2022"}
{"text": "In Fig.\u00a04A, the HBP images for the Naive and 14 d groups appear to contain an overlapping area.In Fig.\u00a05B, there appears to be overlap between the Sham-14 d and HBP-7 d, as well as NMP-1 d and BP-14 d images.In Fig.\u00a09A, the western blot images representing MYD88-1 d and p-I\u03baB\u03b1-7 d, as well as p-I\u03baB\u03b1-Naive and p-p65-7 d appear highly similar.The Editors-in-Chief have retracted this article. After publication, concerns were raised regarding potential image overlap within the published figures. Specifically:The authors have stated that these errors occurred due to mishandling of the data. The Editors-in-Chief therefore no longer have confidence in the presented data.All authors agree to this retraction."}
{"text": "The Oncologist. 2022 [Advance access publication 19 February 2022]. https://doi.org/10.1093/oncolo/oyab069This is a correction to: Nakayama I, Takahari D, Shimozaki K, et al. Clinical progress in inoperable or recurrent advanced gastric cancer treatment from 1004 single institute experiences between 2007 and 2018. In the originally published version of this article, the multivariate analysis values in Table 3, lines \u201cSerum ALP level; \u2264ULN vs ULN<\u201d and \u201cNLR; 4< vs 4\u2264\u201d, were incorrect. The errors were corrected for final publication."}
{"text": "Retraction to: Stem Cell Research & Therapy (2021) 12:444https://doi.org/10.1186/s13287-021-02455-xThe Editors-in-Chief have retracted this article. After publication, concerns were raised regarding the authenticity of the presented data. The authors were unable to provide the raw data for western blot validation, and did not follow the journal's policy for RNA-Seq data sharing. Additionally, in Fig.\u00a05c, the western blot for Ezh1 (lane 2) appears to overlap with Rae28 (lane 1). The Editors-in-Chief therefore no longer have confidence in the data presented in this article.Yongpin Dong, Wenfang Li and Lina Zhang do not agree to this retraction. Chunni Guo and Wuxiong Zhou have not responded to any correspondence from the editor or publisher about this retraction."}
{"text": "The authors regret that the previous version of this article misspelled Graeme Young's name.The authors would like to apologize for any inconvenience caused."}
{"text": "Journal of Healthcare Engineering has retracted the article titled \u201cConstruction of a Physical and Medical Care Integrated Model for the Elderly in the Community Based on Artificial Intelligence and Machine Learning\u201d [earning\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifi"}
{"text": "Cell Death and Disease 10.1038/s41419-019-1652-8, published online 28 May 2019Retraction to: The Editors-in-Chief have retracted this article due to an overlap in the western blot images in figures 4G and 6C. The Editors-in-Chief have therefore lost confidence in the reliability of the results of this study. None of the authors agree to this retraction."}
{"text": "The authors regret that the original version of this paper unfortunately contained an inappropriate representative image of Boyden chamber assay. An inappropriate image was inadvertently used for the HSC-LX2 Ligu+GW9662  during the assembly of this figure. The authors confirm that the correction of Figure 4F does not affect the original conclusions. The authors sincerely apologize for any inconvenience or misunderstanding that the error may have caused. The corrected image is shown below."}
{"text": "Correction to: Environmental Science and Pollution Research (2021) 28:1725\u2013173310.1007/s11356-020-10585-7While reviewing our article we found that in the section \u201cSynthesis of calcium phosphate-based material\u201d the stoichiometric ratio Ca/P was given 1.67 while the actual ratio was 0.6. This corrigendum does not affect the discussion and conclusions of the original paper because the obtained material was characterized correctly. We would like to apologize for any inconvenience caused."}
{"text": "After publication, concerns were raised regarding irregularities in the data in Table 2 and Fig 4. After re-examining the data, the authors provided a correction. However, independent editorial assessment of this correction showed the original conclusions presented in the article are not adequately supported. None of the authors agree with this retraction."}
{"text": "After having been in contact with the authors, they agreed with the decision to retract the paper. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors' attention by a concerned reader that the cell migration assay data shown in Fig. 3B were strikingly similar to data that had appeared in different form in another article by different authors. Owing to the fact that the contentious data in the above article had already been published elsewhere prior to its submission to"}
{"text": "Retraction Note: Cancer Cell Int (2019) 19:156https://doi.org/10.1186/s12935-019-0879-xThe Editors-in-Chief have retracted this article at the corresponding author's request. After publication, the authors found that the data could not be replicated. This was caused by mislabelling of patient blood samples and the use of contaminated cell lines  in this study.The authors therefore no longer have confidence in the presented results.All authors agree to this retraction."}
{"text": "Huang et al., RSC Adv., 2016, 6, 19507\u201319514, DOI: 10.1039/C6RA00002A.Retraction of \u2018Olefin epoxidation with chiral salen Mn( RSC Advances article due to extensive overlap with other published articles by these authors, including the text, data and figures published in RSC Advances article have also been reproduced from The Royal Society of Chemistry, with the agreement of the authors, hereby wholly retracts this Signed: J. Huang, D. W. Qi, J. L. Cai and X. H. Chenth November 2020Date: 19RSC AdvancesRetraction endorsed by Laura Fisher, Executive Editor,"}
{"text": "Figure\u00a02I: overlapping regions are present within this imageFigure\u00a03D: overlapping regions are present within this imageFigure\u00a05A: this image is incorrectFigure\u00a05E and 6H: overlapping regions are present within and between these imagesThe Editors-in-Chief have retracted this article because of the following concerns:The Editors-in-Chief therefore no longer have confidence in the data presented.Authors Xinghong Guo and Xinguo Hou agree with this retraction but disagree with the wording of the retraction notice. All other authors agree to this retraction."}
{"text": "In \u201cUnderstanding and Addressing Variation in Health Care\u2013Associated Infections After Durable Ventricular Assist Device Therapy: Protocol for a Mixed Methods Study\u201d :e14701), the authors noted one error.Acknowledgments section inadvertently included the following incorrect statement:In the originally published paper, the Additional funding was provided by the National Institutes of Health (grant number T32-HL-007853).In the corrected version, this statement has been removed.The correction will appear in the online version of the paper on the JMIR Publications website on June 23, 2022, together with the publication of this correction notice. Because this was made after submission to PubMed, PubMed Central, and other full-text repositories, the corrected article has also been resubmitted to those repositories."}
{"text": "The authors regret that some of the figure citations in the text were incorrect in the original article. The correct figure citations are as follows. On page 11197 the sentence beginning, \u201cFor neurons\u2026\u201d should read, \u201cFor neurons, shown in Fig. 2d, we observed cell viabilities of 73.9 \u00b1 3.6% and 72.9 \u00b1 6.2% on the control substrates and 65.4 \u00b1 4.5% and 66.5 \u00b1 4.4% on the NW substrates.\u201d Additionally, the sentence beginning, \u201cFurthermore, exemplary images\u2026\u201d should read, \u201cFurthermore, exemplary images of stained neurons cultured on both types of NWs are shown in Fig. 2e and f as well as on the control substrates in Fig. S2.\u201dThe Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Journal of Healthcare Engineering has retracted the article titled \u201cEffect of Apatinib Combined with Seggio on the Expression of Serum AFP and CA724 and Long-Term Survival Rate in Patients with Advanced Gastric Cancer Undergoing Comfortable Nursing Intervention\u201d [vention\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifi"}
{"text": "In the original publication, there were mistakes in T. gondii Tachyzoites into the Host Cells: \u201cAdditionally, it is clear that there are more invasive tachyzoites in the control group than in the XYP1-treated group (There was an error in the original publication. According to the correction to The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. The original publication has also been updated."}
{"text": "Journal of Healthcare Engineering has retracted the article titled \u201cStem Cells Promote the Regeneration of Knee Joint Degenerative Bone and Articular Cartilage\u201d [rtilage\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifi"}
{"text": "Retraction Note: BMC Complement Altern Med 13, 10 (2013)https://doi.org/10.1186/1472-6882-13-10The Editor has retracted this article because there are concerns with the histological sections shown in Figure 10, specifically:\u2022 Panels PN and PQ appear to show repeated areas between these two panels\u2022 Panels PN, PQ50, PQ100 and PQ200 appear to show repeated areas within these panelsThe authors have stated that they do not have access to the original data. The Editor therefore no longer has confidence in the results and conclusions reported. None of the authors has responded to the Editor about this retraction."}
{"text": "The research described in ref. 44 has been published, and the full details of this reference are included below:In the original article at the time of publication, ref. 44 had only been uploaded to ChemRXiv (DOI: RSC Adv., 2020, 10, 40284\u201340290.44 S. T. Ngo, H. M. Nguyen, L. T. Thuy Huong, P. M. Quan, V. K. Truong, N. T. Tung and V. V. Vu, Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations, The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "In the Acknowledgements section, a funder, Laboratory Open Project Fund of Capital Normal University (LIP18009S047) was omitted.The revised acknowledgements should read:The authors are grateful to the Key Project of Science and Technology plan of Beijing Education Commission (KZ201910028038), the National Natural Science Foundation of China (21471104) and Laboratory Open Project Fund of Capital Normal University (LIP18009S047).The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "This article has been retracted at the request of the authors due to a mistakenly identifying the scale used as the Wong-Baker FACES Pain Scale, when in fact it was the\u00a0Universal Pain Assessment Tool that was used. Given how heavily this scale is featured within the article, the decision was made to retract after consulting with the Wong-Baker FACES Foundation and Cureus editorial staff. The authors regret the error and any confusion it may have caused."}
{"text": "Authors would like to update the missing text in the abstract section.In the published version:On the other hand, non-operative treatment with optional delayed ACLR may be the more cost-effective.However, it should be:On the other hand, non-operative treatment with optional delayed ACLR may be the more cost-effective strategy in the middle age population with moderate activity levels.The original article has been corrected."}
{"text": "P<0.01 vs the LPS vehicle group, but not the LPS vehicle group vs the Con. The histogram images of mRNA expressions of TGF-\u03b2 and ICAM-1 in Fig.The authors regret that the original version of their manuscript unfortunately contained some typo and incorrect images. The statistical significance for Nuc p65 between the control and LPS vehicle groups was incorrect in Figure The authors confirm that the corrections made in this erratum do not affect the original conclusions. The authors apologize for any inconvenience that the errors may have caused."}
{"text": "The published article  has beenFollowing publication, further data analyses showed that the hybridization signal, which forms the core of the paper, is most likely the result of cross-sample contamination.M. murinus samples is concerning and indicative of contamination. The authors\u2019 previous analyses had shown that M. murinus mitochondrial DNA does not contain a RAD cutting site when digested with the restriction enzyme SbfI , while mtDNA of M. ravelobensis has a cutting site in the COI gene. Nevertheless, some samples of M. murinus show a very low mtDNA coverage and at least some  of these low mtDNA coverages were recently confirmed to be of M. ravelobensis origin, suggesting the presence of very low levels of contaminants (from laboratory work or barcode synthesis). This explanation is the most parsimonious one since proper hybrids should either show high coverage of the M. ravelobensis-type  or no coverage at all .First, the distribution of mitochondrial DNA (mtDNA) coverage among M. murinus and M. ravelobensis prior to RAD Sequencing, and not from hybridization. Taken together these tests leave little doubt that the original publication on hybridization between two sympatric mouse lemur species is compromised by some level of cross-sample contamination.The authors also recently leveraged properties of the minor allele coverage to infer the most likely ploidy of samples  and to inspect the individual profiles of previously inferred \u201chybrids\u201d, using nQuire  and the Consequently, and as a necessity following good scientific practice, the authors contacted the journal regarding the new findings and conclusions and asked for the retraction of the article. They apologize for any inconvenience caused by the retraction.Genes.This retraction was approved by the Editor in Chief of the journal"}
{"text": "After having been in contact with the authors, they agreed with the decision to retract the paper. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors\u2019 attention by a concerned reader that the western blotting data shown in Figs. 3D, 4B and 5A, and certain of the cell migration and invasion assay data shown in Figs. 2C and 5C were strikingly similar to data appearing in different form in other articles by different authors. Owing to the fact that the contentious data in the above article had already been published elsewhere, or were already under consideration for publication, prior to its submission to"}
{"text": "Retraction Note: J Exp Clin Cancer Res 39, 218 (2020)https://doi.org/10.1186/s13046-020-01730-8The Editor in Chief has retracted this article. After publication it was noted that there were irregularities in figures 1A, 2H, 3A, B, D, E, 6A and 7C, when the authors were contacted regarding these issues they were unable to provide the original data. The authors were also unable to provide any evidence of ethics approval for this article.Fuyong Li agrees to this retraction. Shuai Han, Wei Zhen, Tongqi Guo and Jianjun Zou have not responded to any correspondence from the editor/publisher about this retraction."}
{"text": "The word \u201cupholding\u201d has been changed to \u201coverruling.\u201d This article has been corrected.The Special Communication titled, \u201cGraphic Cigarette Warning Labels, the First Amendment, and Public Right to Accurate Public Health Information: Graphic Cigarette Warning Labels Back Under Legal Scrutiny,\u201d"}
{"text": "Computational and Mathematical Methods in Medicine has retracted the article titled \u201cEffect of Stellate Ganglion Block Combined with Lidocaine at Different Concentrations for Preemptive Analgesia on Postoperative Pain Relief and Adverse Reactions of Patients Undergoing Laparoscopic Cholecystectomy\u201d [tectomy\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifi"}
{"text": "Nucleic Acids Research,Volume 33, Issue 18, 1 October 2005, Pages 6000\u20136010, https://doi.org/10.1093/nar/gki897This is an expression of concern about: The Editors were alerted in July 2022 about potential issues with Figures 2C and 3B as detailed below.Figure 2C: ISE3wt SRp75 and ISE3wt SRp55 appear to be identical. ISE3m SRp75 and\u00a0+\u00a0SRp75 appear to be identical.Figure 3B: Lanes 5 and 6 appear to be identical.The Editors have contacted the authors and are referring the matter to the institution where the research was conducted for investigation. In the interim, we advise readers to examine the details of this study with particular care.Julian E. Sale, Barry L. StoddardSenior Executive Editors"}
{"text": "Zingiber officinale mitigates brain damage and improves memory impairment in focal cerebral ischemic rat\u201d [In the article titled \u201cmic rat\u201d , there aThe authors provided the replicate images for each treatment group, which are available in the supplementary materials."}
{"text": "Retraction Note: Alz Res Ther 9, 54 (2017)https://doi.org/10.1186/s13195-017-0280-8The Editors-in-Chief have retracted this article. Following publication, concerns have been raised regarding the western blot images presented in Figs. 1, 5 and 6. The authors have provided the raw data, which have been assessed by independent experts and deemed insufficient to address the concerns. The Editors-in-Chief therefore no longer have confidence in the integrity of the data in this article.Authors Isabelle Guignot, Eva Bouguen, Karine Deschet, Maria Pueyo and Pierre-Jean Ousset agree to this retraction. Author Bruno Vellas agrees to this retraction but disagrees with the Retraction Note. Authors Hoau-Yan Wang, Caryn Trocm\u00e9-Thibierge, Elisabeth Mocaer and Vera Kiyasova do not agree to this retraction. Authors Andres Stucky, Sanket M. Shah, Jessica Kvasic and Amber Khan have not responded to any correspondence from the editor or publisher about this retraction. Author Philippe Morain is deceased."}
{"text": "The representative western blot image for \u03b17AchR protein expression in Fig.\u00a0CRS21d image in Fig.\u00a0We would like to add in the correction that \"the authors clarify that this work was not financially supported by the NIH grants or by the Johns Hopkins University.\"Following the publication of the original article , it was The corrections did not affect the overall conclusions and we hope to make the corrigendum as soon as possible. We apologize for this mistake due to our carelessness."}
{"text": "All the named authors agree to the publication of this Corrigendum, and apologize to the readership for any inconvenience caused.The authors have reassembled"}
{"text": "The authors wish to make the following corrections to this paper . On pageAcknowledgments: The authors wish to express thanks to Almudena Dur\u00e1n and Paloma Jim\u00e9nez for database monitoring and to Guillermo Ortega and Ancor Sanz for hospital clustering.With the following sentence:Acknowledgments: The authors wish to express thanks to Almudena Dur\u00e1n and Paloma Jim\u00e9nez for database monitoring and to Guillermo Ortega and Ancor Sanz for hospital clustering. The authors also wish to thank the members of Grupo EpidemIBD.In addition, add the Appendix section:"}
{"text": "Retraction Note to: Journal of Neuroinflammation (2015) 12:116 https://doi.org/10.1186/s12974-015-0336-2The Editors-in-Chief have retracted this article. After publication, concerns were raised regarding Fig.\u00a05:\u2022 Figures 5A and 5B: the NF-kB panels appear to contain overlapping lanes.\u2022 Figures 5A and 5B: the Actin panels appear to contain overlapping lanes.The data reported in this article are therefore unreliable.Corresponding author XiHong Li has stated that the authors agree with the retraction of the article but disagree with the wording of the retraction notice. Author Dezhi Mu has not explicitly stated whether they agree or disagree with the retraction. The other authors have not separately responded to correspondence regarding this retraction."}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors\u2019 attention by a concerned reader that certain of the western blotting data shown in Figs. 3F, 4A and 5B, and cell migration and invasion assay data shown in Figs. 2C and 5D, were strikingly similar to data appearing in different form in other articles by different authors. Owing to the fact that the contentious data in the above article had already been published elsewhere, or were already under consideration for publication, prior to its submission to"}
{"text": "An increment in the RER at rest was observed with 4 Hz, 6 Hz, 8 Hz and 10 Hz , but not with 1 Hz and 2 Hz (p \u2265 0.923). During uphill walking, the frequency that elicited the highest increase in EE was 6 Hz  compared to the unstimulated condition. None of the impulse frequencies altered the RER during uphill walking. WB-EMS increases EE in healthy young men both during resting and uphill walking.The effects of the different electrical frequencies of whole-body electrical stimulation (WB-EMS) on energy expenditure (EE) and the respiratory exchange ratio (RER) remain poorly understood. This study aimed to determine the effects of different WB-EMS electrical frequencies on EE and the RER during supine resting and uphill walking. A total of 10 healthy and recreationally active men (21.6 \u00b1 3.3 years old) participated in the present study. Participants completed two testing sessions in a randomized order. In each session, a variety of impulse frequencies (1 hertz (Hz), 2 Hz, 4 Hz, 6 Hz, 8 Hz, and 10 Hz) were applied in a randomized order, allowing a 10 min passive recovery between them. Oxygen consumption and carbon dioxide production were measured to calculate EE and the RER. All frequencies increased EE at rest (all  Obesity is a public health problem worldwide since it is a risk factor for cardiovascular diseases and mortality ,2,3,4. EIt is well known that physical exercise is an effective strategy to (i) increase EE, (ii) improve body composition ,17,18,19Only a few studies have investigated the effects of electromyostimulation (EMS) on EE and the respiratory exchange ratio (RER) at rest. For instance, Grosset et al.  reportedElectrical frequency appears to be inversely proportional to electrical intensity, which is commonly applied at a participant\u2019s maximal tolerance and highly influences the effects of WB-EMS . Hence, 2), (iv) not taking medications, (v) any chronic metabolic disease or cancer, and (vi) not suffering from any health problem that might be aggravated by exercise or WB-EMS, such as total endoprosthesis, epilepsy, and abdomen/groin hernia. The participants signed a written informed consent before participation and were fully aware of the nature of the study. The study was approved by the Human Research Ethics Committee of the University of Granada (N\u00b0 1092/CEIH/2020), registered as a clinical trial (NCT05218512), and was conducted following the latest revision of the Declaration of Helsinki .Ten healthy and recreationally active males (18\u201325 years old) participated in the present study. The inclusion criteria were: (i) no previous experience with WB-EMS training, (ii) having a stable body weight (variation of <5 kg in body weight over the previous 3 months), (iii) to show a normal weight status (body mass index (BMI) between 18.5\u201325.0 kg/m2max) or peak oxygen uptake (VO2peak). After seven days, on day 2 , EE and RER were assessed at resting and unstimulated conditions during 30 min followed by the application of 6 different impulse frequencies, in random order, during 6 min each one and with a passive recovery of 10 min between them. During the first 2 min of the 6 min application period, we adjusted the intensity (mA) at the participant\u2019s maximum tolerance, using the last 4 min of the bout to measure the effects of WB-EMS. On day 3 , EE and RER were assessed during 30 min of uphill walking on a treadmill at a speed and grade eliciting an intensity of 60% of the VO2max or VO2peak (without WB-EMS). The same 6 impulse frequencies were tested subsequently while the participants walked on the treadmill, with 10-min recovery periods in between. Notably, the passive recovery was different in both experimental sessions. During the first experimental session, they waited 10 min lying on the stretcher without moving, while during the second experimental session, they waited 10 min seated steadily in a chair.A within-subject repeated measures design was used to compare the effects of different WB-EMS frequencies on EE and RER at rest and during uphill walking . A wide The order of the impulse frequencies was randomly selected and counterbalanced. Participants followed the same order application on both days. Participants were instructed to replicate the same diet the day before each visit, to refrain from moderate (previous 24 h) and vigorous physical activity (previous 48 h), and to abstain from alcohol and caffeine consumption (previous 12 h). All measurements were conducted in a temperature-controlled room (22\u201324 \u00b0C) and performed by the same researchers.2) and lean body mass (kg)/height (m2), respectively.Body weight and height were measured using a Seca scale and stadiometer  with participants being barefoot and wearing light clothing. Body composition was assessed by dual-energy X-ray absorptiometry using a Discovery Wi scanner , obtaining fat and lean mass. The fat mass index (FMI) and lean mass index (LMI) were calculated as fat body mass (kg)/height  exercise test with a progressive incremental protocol that has been extensively used and validated [2) and carbon dioxide production (VCO2) were recorded using a Vyntus CPX Metabolic Cart . Accuracy and reliability of Vyntus CPX has been previously tested [2max was established as [2 change < 100 mL/min in the last 30 s of the final stage, (ii) attaining an RER \u2265 1.1, and (iii) reaching a heart rate between \u00b110 beats/min of the theoretical maximal heart rate. The VO2peak was considered when these criteria were not met [VOalidated ,41,42,43alidated  with 3 my tested . The stuy tested . The achished as : (i) sho not met  and all 2 and VCO2. The gas analyzer was calibrated before every test using the manufacturer\u2019s automated flow and digital volume transducer calibration . The indirect calorimetry\u2019s measurement was performed in agreement with the recommended guidelines [EE and RER were measured while resting, laying in a supine position, between 8 A.M. and 11 A.M. after a 12-h overnight fasting. The participants arrived at the research center by public transportation or by any motor vehicle avoiding any physical activity since waking up. We measured EE and RER in control conditions during a 30-min period with the above-mentioned metabolic cart. The participants were instructed not to move throughout the entire test. A silicone face mask with a twin-tube sample line and a digital volume transducer was used for gas data collection. The measurements were subsequently recorded at 10 s intervals for VOidelines . Briefly2, VCO2 ventilation and RER were calculated, and the periods that met the steady-state criteria  were then selected. Finally, the period with the lowest CV was chosen for further analysis. EE was calculated using the stoichiometry equations of Weir [For control  measurements, the first 5 min data were discarded, and records with an RER <0.7 or >1.0 were excluded. The coefficients of variance for VO of Weir  and exprEE and RER were measured while uphill walking on a treadmill. The grade of the treadmill was personally adjusted to the one that elicited 60% of the VO\u2082max/peak during the maximum effort test. The participants arrived in the same conditions as the first experimental session and had their unstimulated walking EE measured during 30 min followed by the application of the same order of impulse frequencies used in the first experimental session. Data analysis was performed following the same steps as during resting conditions.\u00ae, Malaga, Spain), which simultaneously stimulates 8 muscle groups  (The WB-EMS protocol was performed using an electromyostimulation device (Wiemspro800 cm2) .Since no previous studies have investigated whether the application of different WB-EMS impulse frequencies modifies EE and RER at rest and during uphill walking, we conducted a pilot study selecting a large variety of impulse frequencies, ranging from 1 to 100 Hz. This pilot testing showed that lower frequencies (\u226410 Hz) induced higher EE than those observed with high frequencies (>20 Hz). Therefore, we restricted the frequency range applied in the present study from 1 to 10 Hz.Several electrical parameters were set: (a) the impulse frequency ; (b) impulse intensity ; (c) impulse width ; (d) duty cycle )). Impulse intensity (mA) was adjusted at the participant\u2019s maximum tolerance during the first 2 min of the 6 min application period ,51. Partp > 0.05).Descriptive variables are reported as mean \u00b1 standard deviation. The normality of the distribution of all variables was assessed by the Shapiro\u2013Wilk statistic, visual check of histograms, and Q\u2013Q plots. The data followed a normal distribution and, as a result, a repeated measures analysis of variance (ANOVA) was used to compare the EE and RER elicited by different impulse frequencies  at rest and during uphill walking. The Mauchly test indicated that the sphericity assumption (homogeneity) was met for the effects of impulse frequencies on the EE and RER at rest and during uphill walking , and classified as small, medium, or large , following established guidelines . Post hop \u2264 0.05. All analyses were performed using the Statistical Package for the Social Sciences . Graphical presentations were prepared using GraphPad Prism 8 software .Significance was set at Descriptive data of the participants are shown in p < 0.001, \u019e\u00b2 = 0.828). Post hoc analyses indicated differences in EE between unstimulated and all the stimulated impulse frequencies . Post hoc analyses indicated differences between the unstimulated period and 4 Hz , 6 Hz , 8 Hz , and 10 Hz   = 43.23, = 0.016) b. We con= 0.016) .p < 0.001, \u019e\u00b2 = 0.613) at rest. Post hoc analysis showed that there were notable disparities in perceived pain between control conditions and 6 Hz (p = 0.001) and 10 Hz (p = 0.013) in the majority of the body muscles (p > 0.071) except for 2 Hz and 8 Hz in whole body intensity (p = 0.011), upper back (p = 0.026), lower back (p = 0.009), gluteal (p = 0.044), and hamstrings (p = 0.044) at rest  = 9.48,  muscles . There w at rest .p < 0.001, \u019e\u00b2 = 0.501). Post hoc analyses indicated differences in EE between the unstimulated condition and 2 Hz, 6 Hz, and 8 Hz  but not for 1 Hz, 4 Hz, and 10 Hz  . However, post hoc analyses indicated no significant differences in RER between the control conditions and any of the frequencies applied  = 7.02, \u2265 0.063) c. We obsp < 0.001, \u019e\u00b2 = 0.632). Post hoc analysis only showed a higher pain perception at 4 Hz in low back (p = 0.041), hamstrings (p = 0.007), and gluteal (p = 0.046) compared to control conditions (p = 0.046), 6 Hz (p = 0.046), 8 Hz (p = 0.007), and 10 Hz (p = 0.008)  = 10.28, nditions . There w= 0.008)  but not To the best of our knowledge, this is the first study aiming to elucidate which is the WB-EMS impulse frequency that elicits the highest increase in EE at rest and during uphill walking. We observed that 4 Hz induces the highest EE at rest , whereas 6 Hz seems to produce the most extensive EE during uphill walking . There were also other frequencies that elicit significant increases in EE at rest  compared to unstimulated conditions and during uphill walking . A significant increase in the RER at rest was induced by 4 Hz, 6 Hz, 8 Hz, and 10 Hz, but not by low frequencies such as 1 Hz and 2 Hz. Lastly, there were no significant effects of WB-EMS on the RER during exercise. These results suggest that a single bout of WB-EMS at 4 Hz and 6 Hz (adjusting impulse intensity to the participant\u2019s maximum tolerance) induces the highest increase in EE at rest and during uphill walking, respectively. Although 4 Hz seems to be the frequency that elicits the highest increase in EE, there were no significant differences between 4 Hz, 6 Hz, and 8 Hz at rest. Similarly, during uphill walking, we did not find significant differences between 6 Hz, 2 Hz, and 8 Hz. Intriguingly, although 1 Hz and 2 Hz do not change the RER values, they increase EE at rest suggesting a potential impact on substrate utilization.There are previous studies investigating the impact of local EMS on EE at rest. Grosset et al.  compared2 comparing Nordic walking and walking with and without WB-EMS. They continuously applied WB-EMS during 10 min with the following pattern: 9 s at 85 Hz and 1 s at 7 Hz, with a pulse width 350 \u03bcsec in every muscle stimulated at the individual tolerated maximum intensity [2 elicited by WB-EMS [Regarding WB-EMS stimulation during exercise, Kemmler et al.  showed antensity . Interesy WB-EMS . The comy WB-EMS  findingsy WB-EMS .The RER indicates the prevalence of one substrate utilization , provided that some assumptions are met . We obsep < 0.001) due to the incompatibility of walking with high intensities. This fact would explain why the RER values rise to higher levels at rest than during uphill walking. Concretely, we found that the RER values at 10 Hz at rest were 1.04 \u00b1 0.16, while during uphill walking the were 0.95 \u00b1 0.08 at the same frequency.Electrical frequencies and intensities are inversely proportional and the relationship between both parameters could explain the differences observed in EE. Intensity has been positioned as a crucial parameter to modulate EE. For instance, Hsu et al.  demonstrWe showed that the application of low frequencies of WB-EMS at rest produces an EE level similar to the one observed during uphill walking . This could be of interest for individuals with severe obesity problems since long aerobic training sessions at moderate intensity could lead to joint and biomechanical imbalance increasing injury risk , as wellThe present study had several limitations. Although we found significant differences between frequencies, the limited sample size should be considered. Moreover, we only measured the effects of each frequency during 4 min, not enough time to talk about substrate oxidation despite being measured . This isThe present study shows that relatively low frequencies of WB-EMS are an effective tool to increase EE at rest and during uphill walking in young healthy adults. Specifically, although 4 Hz is the frequency that elicits the major increment in EE at rest, other frequencies such as 2 Hz, 6 Hz and 8 Hz also did this compared to unstimulated conditions. In addition, the frequency that produces the highest increment in EE during uphill walking is 6 Hz, having a similar effect with 2 Hz and 8 Hz, compared to unstimulated conditions. Lastly, low frequencies (1 Hz and 2 Hz) of WB-EMS do not increase the RER values despite an increase in EE at rest suggesting that it could have an impact on fuel utilization rates."}
{"text": "Bioscience Reports at the request of the authors following receipt of a notification from a reader alerting the Editorial Office to western blot bands that appear in both this paper and another paper by different authors (doi: 10.1186/s12935-019-0985-9). The authors wish to retract the article. The Editor-in-Chief and Editorial Board agree with the retraction.This Retraction follows an Expression of Concern relating to this article previously published by Portland Press. This article is being retracted from"}
{"text": "This article has been retracted: Aging has completed its investigation of this paper. We found overlap between some of the transwell assay images used for Figures 3E and 5E and data published by other authors. We also found that images of exosomes isolated from the medium of NEEC and EC18 cells in Figure 4B duplicate exosome images from different cells published in unrelated papers. The authors reply that they \u201care unable to provide satisfactory data in relation to these figures and were unable to support the integrity of the research.\u201d Consequently, all authors agreed that the article should be retracted."}
{"text": "In the original article, in Section 4.11 REMD simulations, the number of replicas, their average exchange probability and the temperature range utilized were inaccurately reported as 32, 20% and 290\u2013500 K, respectively. However, the presented results were obtained using 48 replicas, with an average exchange probability of 13% and a temperature range of 298\u2013380 K. The authors regret this error. The scientific conclusions of this article remain unchanged.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Treatment and prevention alone are unlikely to make a significant difference in reducing the burden of poor mental health and mental illness. Therefore, mental health promotion (MHP) initiatives are advocated. In 2014, the ABCs of mental health (ABCs) partnership was established in Denmark; in the partnership, partner organisations, e.g., municipalities and NGOs, use a research-based framework for MHP, the ABC-framework, to develop and implement MHP initiatives. This presentation has two aims: (1) to outline the overall characteristics of these MHP initiatives; and (2) to explore local coordinator and stakeholder perceptions of the implementation processes and the impact of the MHP initiatives. Questionnaire surveys, individual interviews and group interviews were conducted during 2017-2020. The MHP initiatives were grouped according to three strategies: building MHP capacity, campaign activities to promote mental health awareness and knowledge and establishing and promoting opportunities to engage in mentally healthy activities. The ABC-framework was positively received and viewed as providing relevant knowledge for working with MHP as well as fostering intersectoral and interprofessional collaborations. However, using a bottom-up approach to develop and implement MHP initiatives can be time-consuming and resource demanding, and it requires a deliberate balancing of local adaptability and concrete guidance when engaging stakeholders and implementers. Overall, using the ABC-framework to develop and implement MHP initiatives holds great promise for advancing and promoting MHP practice."}
{"text": "Secondly, the authors have subsequently realized that certain of the primer sequences featured in Following the publication of this article, the authors regret that the paper contained some errors that should have been corrected before the article went to press. First, in the Materials and methods section, \u201cExperimental and Therapeutic Medicine for allowing them the opportunity to publish this corrigendum, and allt he authors agree with its publication. The authors also regret any inconvenience that this mistake has caused.The authors are grateful to the Editor of"}
{"text": "The corrected inset for The authors regret that there is an error in the inset of In addition, we would like to update section \u20182.2 Characterization\u2019 to include the following information.\u201cThe magnetic measurement was performed on an MPMS 3 (Quantum-Design) at room temperature and the magnetic moment was measured in the magnetic field range of \u221220.0 to +20.0 kOe.\u201dThe authors confirm that this correction does not affect the discussion and conclusions of the original article. The authors would like to apologize for any inconvenience caused.An independent expert reviewed the raw data provided by the authors and concluded that it was consistent with the corrected figure and does not change the discussions or conclusions presented in the article.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Journal of Healthcare Engineering has retracted the article titled \u201cComparison between Ibuprofen and Acetaminophen in the Treatment of Infectious Fever in Children: A Meta-Analysis\u201d [nalysis\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifi"}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors' attention by a concerned reader that certain of the data shown for the cell invasion assays in Figs. 2C and 4C were strikingly similar to data appearing in different form in other articles by different authors. Owing to the fact that the contentious data in the above article had already been published elsewhere, or were already under consideration for publication, prior to its submission to"}
{"text": "The temperature on the surface of the immobilized catalyst could reach as high as 139 \u00b0C within 15 min IR irradiation. Due to the aforementioned advantages, the as-prepared catalyst exhibited excellent IR-triggered catalytic performance toward EMF production, where the EMF yields and selectivity were as high as 45% and 65%, respectively. The high catalytic performance originates from the outstanding photo-to-thermal conversion by the introduction of BCQDs, as well as the strong interactions between BCQDs and UiO-66-NH2 that boosts the etherification reactions. The immobilization of catalyst on cermasite not only benefits catalyst recycling, but more importantly reduces catalyst loss during practical applications. The conceptual study shown here provides new viewpoints in designing energy-effective materials for the conversion of wastes into high-value-added resources. The catalytic etherification of 5-hydroxymethylfurfural (HMF) with the waste ethanol into high-energy-density 5-ethoxymethylfurfural (EMF) has been considered as a promising way to simultaneously alleviate the energy crisis and environmental pollution. However, the energy consumption is rather high as the synthesis of EMF requires a high temperature to open the etherification reaction. Herein, we demonstrate a clever design and construction of acidified biomass-derived carbon quantum dots (BCQDs)-modified UiO-66-NH Among them, NA0 is the initial molar amount of HMF, NA is the residual molar amount of HMF after the reaction, and NB is the molar amount of EMF after the reaction.An infrared lamp , simulating the solar light, was employed as input driven energy to trigger the etherification reaction. The output wavelength was set as \u03bb > 750 nm. Typically, 50 mg of H+/BCQDs/UiO-66-NH2 is synthesized via a combined synthetic strategy of immerse and acidification treatment, where the as-prepared UiO-66-NH2 is firstly immersed in the BCQDs solution to obtain BCQDs/UiO-66-NH2, then the composites are further acidified by hydrochloride acid to form H+/BCQDs/UiO-66-NH2. As shown in +/BCQDs/UiO-66-NH2 features a particle morphology with a dense, stacked structure. An enlarged observation indicates the amorphous structure of the UiO-66-NH2 host material, as no obvious lattice fringes can be observed in the HRTEM images  of these two materials. As the C, N, O, S, and P elements are derived from the BCQDs according to our previously reported results [2. Moreover, it is interesting to note the uniform distribution of Cl\u2212 on the entire material. Since the Cl is not a constituent element of both UiO-66-NH2 and BCQDs, the observation of Cl distributing well on the materials is indicative of the successful protonation of BCQDs/UiO-66-NH2 that introduces Cl as charge compensation to that of H+. These results demonstrate the successful construction of H+/BCQDs/UiO-66-NH2. The powder-form acid catalyst of HM images b,c. This results ,32, the +/BCQDs/UiO-66-NH2, forming an easily recyclable immobilized catalyst of H+/BCQDs/UiO-66-NH2@ceramsite. As depicted in +/BCQDs/UiO-66-NH2. The dark color shown here not only suggests the successful immobilization of catalyst on the ceramsite, but also reflects the excellent light absorption property of the as-prepared immobilized catalyst [+/BCQDs/UiO-66-NH2 composed elements are found to be well distributed on the ceramsite. Especially, the Cl element is also found distributed on the material with an atomic content of 1.7%, demonstrating the successful installation of active sites on the immobilized material. Based on the above analysis, the immobilized H+/BCQDs/UiO-66-NH2@ceramsite catalyst has been successfully fabricated.In energy- and environmental-related areas, the difficulty in catalyst recycling is a bottleneck that restricts the practical application of powder-form catalyst. To overcome this drawback, we then chose ceramsite as a host material to immobilize the powder-form catalyst of Hcatalyst ,34 (whic2, H+/UiO-66-NH2, BCQDs/UiO-66-NH2, and H+/BCQDs/UiO-66-NH2 were further investigated by performing a nitrogen sorption\u2013desorption isothermals test. As shown in 2, H+/UiO-66-NH2, BCQDs/UiO-66-NH2, and H+/BCQDs/UiO-66-NH2 were respectively tested and are shown to be 511, 535, 311, and 661 m2\u00b7g\u22121. It should be noted here that the acidification process could affect the porosity structure via H+ corrosion, thus causing H+/UiO-66-NH2 and H+/BCQDs/UiO-66-NH2 to exhibit a much higher surface area than that of the UiO-66-NH2 and BCQDs/UiO-66-NH2 counterparts. It is worth noticing here that the introduction of BCQDs on the MOFs led to a decrement in surface area by blocking the pores of the MOFs, as supported by the surface area decrement from 511 to 311 m2\u00b7g\u22121. However, the H+ etching of both the BCQDs and UiO-66-NH2 created abundant pores on both components. This can be further evidenced by the pore size distribution results shown in +/BCQDs/UiO-66-NH2 shows much higher pore volume that that of BCQDs/UiO-66-NH2. In addition, no obvious structure destruction can be found from the FT-IR results in It is believed that the catalytic activity of a catalyst is sensitive to the porosity structure, which affects the mass transfer and exposure number of active sites; thus, the as-prepared materials of UiO-66-NH2, H+/UiO-66-NH2, BCQDs/UiO-66-NH2, and H+/BCQDs/UiO-66-NH2 were further investigated by XPS. As shown in +/BCQDs/UiO-66-NH2 catalyst. Furthermore, all the materials produced comparable C 1s, N 1s, O 1s, and Zr 3d XPS spectra, demonstrating the high structural stability of UiO-66-NH2 against the modification of BCQDs and acidification treatment [2. This is further supported by the observation of the shift of O 1s and Zr 3d XPS spectra of BCQDs/UiO-66-NH2 toward a higher binding energy direction than that of the UiO-66-NH2 counterpart [+/BCQDs/UiO-66-NH2 give an additional shift toward higher binding energy compared with that of BCQDs/UiO-66-NH2, suggesting that the acidification treatment could have further promoted the interactions between BCQDs and UiO-66-NH2. The chemical structure of as-prepared catalysts of UiO-66-NHreatment . It shounterpart ,6. Surpr2 facilitated the interactions between BCQDs and UiO-66-NH2 and showed a shift of XPS spectra toward the blue direction, we then used this phenomenon as an indicator to probe the successful introduction of protons on the BCQDs/UiO-66-NH2. As shown in 2 is deconvoluted into two peaks with binding energies of 182.5 and 184.9 eV, respectively, assigned the Zr 3d5/2 and 3d3/2 levels [3/2 and 2p1/2 levels [2 shift toward the higher binding energy direction, indicating the successful introduction of proton sites on the composites after the facile hydrochloride acid treatment. This can be further confirmed by the Cl 2p spectra in +/BCQDs/UiO-66-NH2, which is deduced from the atomic amount of Cl in the composite. As the acidification of as-prepared material of BCQDs/UiO-66-NH2 levels , while t2 levels . Moreove2 levels . The mor2 host. The amount of BCQDs introduced and the concentration of hydrochloric acid used for the acidification are two key factors determining the catalytic performance of H +/BCQDs/UiO-66-NH2. In this regard, a systematic study was carried out, and the results are shown in +/BCQDs/UiO-66-NH2 synthesis was too high, the excess BCQDs aggregated into large carbon, which not only led to the sharp decrement of active sites for the catalytic reaction, but more importantly decreased the EMF production selectivity. This can be further supported by the selectivity decrement from 67% to 24% shown in We first evaluated the catalytic performance of as-prepared powder-form catalysts by using an electric furnace to heat the reaction flask so as to hold the reaction temperature of 100 \u00b0C. In this work, a combined BCQDs modification and acidification treatment was employed to functionalize the UiO-66-NH+ sites. The maximum EMF production activity was achieved when the HCl used for catalyst acidification was diluted 2 times, where the EMF yield reached 55% with the HMF-to-EMF selectivity of 66.9%. However, without diluting the HCl solution, the concentrated HCl with a highly corrosive property would largely etch the catalyst, leading to structure damage. As a result, both the EMF production yield and the HMF-to-EMF selectivity decreased from 55% and 66.9% to the final 28.9% and 65.1%, respectively. Based on the above results, the optimized conditions for catalyst synthesis were established and the optimized condition was used for the materials construction thereafter. To investigate the effect of the HCl concentration used for the catalyst acidification on the catalytic activity toward the conversion of HMF to EMF, HCl was diluted 1, 2, 4, and 8 times before the acidification treatment. As depicted in 2, H+/UiO-66-NH2, BCQDs/UiO-66-NH2, and H+/BCQDs/UiO-66-NH2, where the materials were fabricated based on the aforementioned optimized synthetic method. As shown in 2 nor for BCQDs/UiO-66-NH2, highlighting the importance of introduced H+ sites for converting HMF into EMF. It is interesting to find that although the EMF yield on these two catalysts was zero, more than 45% of HMF was converted. The HFM conversion on these two materials was due to the side reactions that covert HMF into other kinds of byproducts. After the acidification treatment, a noticeable EMF yield was then found on H+/UiO-66-NH2; however, the selectivity for the etherification of HMF into EMF was as low as 4.7%; while the selectivity for the etherification of HMF to EMF was almost 100%, demonstrating that the introduction an of H+ site on UiO-66-NH2 cannot prevent the unwanted serious side reaction. Excitingly, H+/BCQDs/UiO-66-NH2 exhibited excellent catalytic activity toward EMF generation, where the EMF yield and selectivity values reached as high as 55% and 66.9%, respectively. The enhanced catalytic activity should lead to the strong interactions between the BCQDs guest and UiO-66-NH2 host that suppresse the side reactions during the etherification of HME to EMF [We further investigated the catalytic performance of UiO-66-NHE to EMF , which i+/BCQDs/UiO-66-NH2 on to the ceramsite so as to make it easy for catalyst recycling. As shown in +/BCQDs/UiO-66-NH2@ceramsite shows excellent light absorption ability in the full range of solar light. Such an excellent light absorption, especially for the high IR light absorption property shown here, is beneficial for photo-to-thermal conversion. Before performing the IR-light-triggered etherification reactions, we first tested the light absorption property of the as-prepared catalysts, as the light absorption ability is a key factor affecting the IR light driving catalytic performance. As shown in +/BCQDs/UiO-66-NH2@ceramsite. Here, a 150 W IR light was the IR source used to simulate the solar light. As shown in With a high light absorption property, an infrared thermal imaging camera was employed to evaluate the photo-to-thermal conversion performance of H+/BCQDs/UiO-66-NH2@ceramsite using IR as input driven energy. Firstly, we studied the effect of calcination temperature during the immobilization of BCQDs/UiO-66-NH2 on the ceramsite on the final catalytic activity. As shown in 2, which suppressed the side reaction during the etherification of HMF to EMF. However, further raising the annealing temperature would more or less destroy the skeleton of the MOFs, thus reducing the catalytic activity. In addition, the higher temperature would inevitably lead to the sintering of the material, effecting the interactions between the BCQDs and UiO-66-NH2 [2 as well as the adhesive of BCQDs/UiO-66-NH2 on ceramsite is 300 \u00b0C.Based on the above analysis, we then carried out the catalytic etherification reaction by using the immobilized material of HO-66-NH2 . As a re+/BCQDs/UiO-66-NH2@ceramsite under these two conditions. As shown in 2 by high-temperature calcination during the immobilization process. To highlight the merits of using IR light instead of electric heat as driven energy to open the etherification reaction, we then evaluated the catalytic activity of H+/BCQDs/UiO-66-NH2@ceramsite was evaluated by four consecutive catalytic etherification cycles of HMF with ethanol to EMF. After each cycle, the immobilized catalyst was taken out of the system and washed with deionized water at least three time, and the catalyst was further dried before using it in the next cycle. As shown in +/UiO-66-NH2, H+/BCQDs/UiO-66-NH2 and H+/BCQDs/UiO-66-NH2@ceramsite are then illustrated in It is well accepted that catalyst stability is a very importance factor determining the large-scale practical application of the immobilized catalyst. In this regard, the stability of H+ /BCQDs/UiO-66-NH2 and H+ /BCQDs/UiO-66-NH2@Ceramsite were successfully prepared through simple steps using low-cost raw materials. The as-prepared catalysts showed considerably high catalytic activity toward the synthesis of EMF from HMF owing to the large specific surface area of UiO-66-NH2; a large number of acid catalytic active sites were exposed on the catalyst surface. The BCQDs and H+ can be successfully loaded onto the surface of UiO-66-NH2 due to the surface \u2212NH2 groups on the UiO-66-NH2. Based on the catalytic test results, the highest acid catalytic activity of H+ /BCQDs/UiO-66-NH2 toward the directional transformation of HMF among all the tested materials can be attributed to the internal synergy between BCQDs and H+ in H+ /BCQDs/UiO-66-NH2. Moreover, the prepared immobilized acid catalyst H+ /BCQDs/UiO-66-NH2@Ceramsite showed pretty infrared absorption characteristics. The heat collection property of ceramsite carrier causes the H+ /BCQDs/UiO-66-NH2@Ceramsite to exhibit excellent acid catalytic activity regardless of heating or infrared irradiation. Therefore, the prepared H+ /BCQDs/UiO-66-NH2@Ceramsite catalyst is not only expected to be applied to industrial-scale production, but is also a broad prospect for photothermal co-catalysis.In this study, powder and immobilized heterogeneous acid catalysts H"}
{"text": "Figure 5, panes d and f as published. We have noticed that, in panels d and f, the images of TG in SKBR3 cells (d) have been unintentionally duplicated in panel f (T47D cells). The corrected Figure 5 appears below.In the original publication , there wThe authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "Journal of Healthcare Engineering has retracted the article titled \u201c\u03ba-Opioid Receptor Agonist Ameliorates Postoperative Neurocognitive Disorder by Activating the Ca2+/CaMKII/CREB Pathway\u201d [Pathway\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifiThe authors do not agree to the retraction."}
{"text": "We read the report by Conner and colleagues that tested whether kiwifruit or vitamin C affected measures of vitality . The triWe contacted the authors to inquire about their design after reading their methods, which included references to \u2018batch randomization\u2019 and challenges with stratification. The authors expeditiously shared their data, code, and additional detail on their design. We thank the authors for their collegiality in communication.https://doi.org/10.31219/osf.io/ehk3x (accessed on 26 April 2021) for our understanding of the design). We elaborate on the different aspects of nonrandom, random, restricted random, and group random methods at https://doi.org/10.31219/osf.io/ehk3x (accessed on 26 April 2021). The design choices change requirements for the analysis and communication of the trial as an RCT. We outline two errors below.Through discussion, we learned that some participants were not randomly assigned, while some were group-randomized, and others individually randomized , this is conventionally referred to as group-randomized or cluster-randomized and referred to by Conner et al. as \u2018batch randomized\u2019. With group-randomization, the model residuals are \u2018correlated\u2019  and thiiid , but theiid .We encourage the authors to provide readers additional detail on their methods as they generously shared with us, which is essential for interpreting this study. We note a similar example of the Primary Prevention of Cardiovascular Disease with a Mediterranean Diet (PREDIMED) trial, in which, just as in this trial, the nonrandom allocation of some of the participants and some group-randomizations were uncovered in a trial audit . In that"}
{"text": "The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an Expression of Concern to notify readers whilst the Editorial Office investigates. An apparent duplication has been identified between the si-NC and the miR-143-3p mimic + pcDNA-MSI2 panels of Figure 7H."}
{"text": "Correction to: BMC Infect Dis 22, 679 (2022)https://doi.org/10.1186/s12879-022-07649-z.Prior to the publication of this article several changes could not be implemented. These changes are:The text:Records identified through electronic search: CINAHL, Cochrane Library, Google Scholar, MEDLINE, PsychINFO, ProQuest Central and Web of Science datababes, Cambridge and Oxford journals, UNAIDS and WHO websites (n = 7823)Should read:Records identified through electronic search: Cambridge Core, CINAHL, Cochrane Library, Google Scholar, MEDLINE, ProQuest Central, PsycINFO, Oxford Journals and Web of Science databases, UNAIDS and WHO websites (n = 7823)The text:Author, year & title.Should read:Author & year.The original publication has been updated to correct these errors."}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors\u2019 attention by a concerned reader that certain of the cell invasion assay data shown in Fig. 3D were strikingly similar to data appearing in different form in another article by different authors. Owing to the fact that the contentious data in the above article had already been published elsewhere prior to its submission to"}
{"text": "In"}
{"text": "This abstract has been withdrawn."}
{"text": "Abstract: ; Results: 9678 participants .There were some errors in the original publication in the Abstract and Results sections . AbstracAbstract, line 6: ; Results, Paragraph 1, line 1: 9775 participants .A correction has been made to The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors\u2019 attention by a concerned reader that several of the panels shown for the cell invasion assays in Figs. 2C and 5D were strikingly similar to data appearing in different form in other articles by different authors. Owing to the fact that the contentious data in the above article had already been published elsewhere, or were already under consideration for publication, prior to its submission to"}
{"text": "All authors have read and agreed to the published version of the manuscript.After updating:Conceptualization, S.M.H.; validation, E.B., M.G. and S.M.H.; formal analysis, S.M.H. and P.Z.; data curation and visualization, M.G. and C.P.; writing\u2014review and editing, S.M.H., E.B.; C.P. and P.Z.; project administration, S.M.H. and M.R.N. All authors have read and agreed to the published version of the manuscript.The authors apologize for any inconvenience caused and state that the change does not affect the results of the study and the conclusions drawn from it. The original publication has also been updated."}
{"text": "In the original publication , there wThe authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "In the original publication , there wB. caccae, which was correct. The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated.In the original publication, there was also a mistake in Supplementary Figure S3 as published. We inverted the water and ciprofloxacin labels by mistake for all bacterial growth curves, except for"}
{"text": "The source of primary HPMECs is incorrectly stated as ATCC, and the cell culture conditions described in the Methods are unsuitable for primary cells.The flow cytometry assay described in the Methods does not match the presented data.The same western blot control bands are used in Figs. 2 and 3, and in Figs. 4 and 5.The Editor-in-Chief has retracted this Article. After publication, concerns were raised regarding the methodology and data presented, specifically:The authors have provided raw flow cytometry data, which is inconsistent with the results presented in the Article and contains duplication between various samples. The authors have been unable to provide full uncropped western blot gel images for verification upon the Editors' request. Additionally, the Article was simultaneously submitted to and published by another journal [All authors agree to this retraction."}
{"text": "The journal retracts the 30 April 2021 article cited above.Following publication, concerns were raised regarding the integrity of the images in the published figures. The authors failed to provide a satisfactory explanation and complete raw dataset during the investigation, which was conducted in accordance with Frontiers' policies. Given the concerns about the validity of the data and the figures, and the lack of complete raw data, the article has been retracted.This retraction was approved by the Chief Editors of Cardiovascular Medicine and the Chief Executive Editor of Frontiers. The authors agree to this retraction."}
{"text": "In \u201cAmbient Assisted Living: Scoping Review of Artificial Intelligence Models, Domains, Technology, and Concerns\u201d :e36553) the authors noted one correction.Under \u201cAcknowledgments\u201d, the sentence:This work was part of and supported by GoodBrother, COST Action 19121\u2014Network on Privacy-Aware Audio- and Video-Based Applications for Active and Assisted Living.has been replaced by:This publication is based upon work from COST Action GoodBrother\u2014Network on Privacy-Aware Audio- and Video-Based Applications for Active and Assisted Living (CA19121), supported by COST (European Cooperation in Science and Technology).The correction will appear in the online version of the paper on the JMIR Publications website on December 20, 2022 together with the publication of this correction notice. Because this was made after submission to PubMed, PubMed Central, and other full-text repositories, the corrected article has also been resubmitted to those repositories."}
{"text": "The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, including suspected nonsensical data in Figure 6A, a duplication within Figure 2A between the CD31 and CD34 LEDVT panels, and western blots in Figures 4C and 8E that appear to have no background. The authors have been contacted with regards to these concerns but have currently not responded to the Journal's queries."}
{"text": "Missing CitationThe authors wish to make the following correction to the published paper , the citThe authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "Journal of Healthcare Engineering has retracted the article titled \u201cPrediction Effect of Amplitude-Integrated EEG on the Brain Damage and Long-Term Nervous System Development of Late Preterm Infants\u201d [Infants\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifi"}
{"text": "Correction made is listed below.The sepsis model was induced via the CLP method. Briefly, the mice were anaesthetized with pentobarbital (50 mg/kg) by intraperitoneal injection, and their lower abdomen was then shaved.In the Materials and Methods section under the sub-heading \u201c(3)In the section of ethics approval and consent to participate: All of the experimental procedures were approved by the Southeast University Ethics Committee (protocol number: 20171101006).The original article  containsThese corrections will not affect the result and scientific conclusion of the manuscript. The authors would like to apologize for any inconvenience caused."}
{"text": "Molecular Genetics & Genomic Medicine. 2019, 7(8), e757. https://doi.org/10.1002/mgg3.757Chen, T., Qin, S., Gu, Y., Pan, H. & Bian, D. \u201cLong non\u2010coding RNA NORAD promotes the occurrence and development of non\u2010small cell lung cancer by adsorbing MiR\u2010656\u20103p\u201d. https://onlinelibrary.wiley.com), has been retracted by agreement between the journal Editor in Chief Dr. Suzanne Hart and John Wiley & Sons. The retraction has been agreed due to concerns raised by a third party about image manipulation. The journal team has investigated and determined that the image manipulation undermines the reliability of the data presented and the article's conclusions.The above article, published online on 17 June 2019 in Wiley Online Library ("}
{"text": "The corrected images for Figure The authors regret that the original version of our paper, unfortunately, contained incorrect pictures in Figure The correction made in this erratum does not affect the original data and conclusions. The authors apologize for any inconvenience that the errors may have caused."}
{"text": "In \u201cEvaluating the Quality of Asynchronous Versus Synchronous Virtual Care in Patients With Erectile Dysfunction: Retrospective Cohort Study\u201d :e32126), the authors noted the following corrections:1. In Discussion section:2. In the original paper, the following sentence was present in the The recent widespread adoption of telehealth as an acceptable treatment modality and the exploration for potential expansion of traditional methods outside the scope of synchronous care have prompted deeper exploration of the downstream effects of these approaches to care distribution.This has been changed to:The recent widespread adoption of telehealth as an acceptable treatment modality and the potential expansion of asynchronous care have prompted deeper exploration of the downstream effects.3. The phone number of the corresponding author, Lauren Broffman, has been updated to 1 888 798 8686.The correction will appear in the online version of the paper on the JMIR Publications website on July 27, 2022, together with the publication of this correction notice. Because this was made after submission to PubMed, PubMed Central, and other full-text repositories, the corrected article has also been resubmitted to those repositories."}
{"text": "This abstract has been withdrawn"}
{"text": "The authors wish to revise the second citation of reference [26] to [27] in the original article main text  and add On page 7, the original sentences are as follows: The response to the pandemic required that we adapt quickly based on the local context and required the funding organizations to allow flexibility in fund utilization. There is also a need to increase the share of TB domestic funding to allow implementers more flexibility in adapting quickly and without bureaucratic hurdles [26].The correction is as follows: The response to the pandemic required that we adapt quickly based on the local context and required the funding organizations to allow flexibility in fund utilization. There is also a need to increase the share of TB domestic funding to allow implementers more flexibility in adapting quickly and without bureaucratic hurdles [27]. 27.Trop. Med. Infect. Dis.2019, 4, 146. https://doi.org/10.3390/tropicalmed4040146.Malik, A.A.; Hussain, H.; Creswell, J.; Siddiqui, S.; Ahmed, J.F.; Madhani, F.; Habib, A.; Khan, A.J.; Amanullah, F. The Impact of Funding on Childhood TB Case Detection in Pakistan. The authors regret any inconvenience caused by this correction and assure that the scientific conclusions are unaffected. The original article has been updated accordingly."}
{"text": "In \u201cThe Effect of an App-Based Home Exercise Program on Self-reported Pain Intensity in Unspecific and Degenerative Back Pain: Pragmatic Open-label Randomized Controlled Trial\u201d :e41899) the authors made one addition.Under Acknowledgments, the following sentence has been added:The authors acknowledge the work of Markus Klingenberg, who developed the therapy concept of the medical software device assessed in this research. This includes the digital implementation of the functional therapeutic approach, the device\u2019s software-patient feedback interface, and its exercise progression algorithm.The correction will appear in the online version of the paper on the JMIR Publications website on February 20, 2023 together with the publication of this correction notice. Because this was made after submission to PubMed, PubMed Central, and other full-text repositories, the corrected article has also been resubmitted to those repositories."}
{"text": "DOI: 10.1039/C9RA06487G.Correction for \u2018Research status, industrial application demand and prospects of phenolic resin\u2019 by Yanru Xu  China Adhesives,1 and should have been cited in this RSC Advances article. In their RSC Advances article, the authors included additional information about increasing the production and consumption data of phenolic resin in the global market. Further information about new technologies and modification research on phenolic resin  was also included in the English article.The authors wish to draw the readers\u2019 attention to their closely related paper written in Chinese, which was published at nearly the same time in The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "The authors regret \u2018Please change the acknowledgment to: The present publication is the outcome of the project \u201cProject no. TKP2020-NKA-02 has been implemented with the support provided from the National Research, Development and Innovation Fund of Hungary, financed under the T\u00e9mater\u00fcleti Kiv\u00e1l\u00f3s\u00e1gi Program funding scheme.\u201d.The authors would like to apologise for any inconvenience caused.The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper."}
{"text": "Journal of Healthcare Engineering has retracted the article titled \u201cA Novel Structure of Blockchain Applied in Vaccine Quality Control: Double-Chain Structured Blockchain System for Vaccine Anticounterfeiting and Traceability\u201d [ability\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifiThe authors agree to the retraction."}
{"text": "Scientific Reports 10.1038/s41598-022-26963-9, published online 29 December 2022Correction to: Damien Brevers was omitted from the author list in the original version of this Article. As a result, the Author contributions section now reads:\u201cA.L.: Conceptualization, Validation, Visualization, funding acquisition, Investigation, Methodology, Project Administration, Supervision, Writing\u2014Original Draft Preparation and Review & Editing; M.G.: Conceptualization, Investigation, Methodology, Project Administration, Supervision, Writing\u2014Review & Editing; J.G.: Conceptualization, Investigation, Methodology, Project Administration, Supervision, Writing\u2014Review & Editing; S.B.: Conceptualization, Investigation, Methodology, Project Administration, Supervision, Writing\u2014Review & Editing; J.C.: Conceptualization, Investigation, Methodology, Project Administration, Supervision, Writing\u2014Review & Editing; H.D.: Conceptualization, Investigation, Methodology, Project Administration, Supervision, Writing\u2014Review & Editing; T.B.: Investigation, graphical development of the pictograms, Writing\u2014Review & Editing; L.R.: Conceptualization, Investigation, Methodology, Project Administration, Supervision, Writing\u2014Review & Editing; M.G.-B.: Conceptualization, Investigation, Methodology, Project Administration, Supervision, Writing\u2014Review & Editing. S.A., B.B., J.B., D.B., A.B., P.B., G.C.-B., M.C., L.C., A.C., J.-M.C., G.D., R.D., A.E., G.G., A.H., Y.K., D.L.K., F.L., H.L., P.N., J.C.P., A.R., G.S., S.S., P.T., I.V., C.V.H. were members of the Delphi panel and contributed as well in data analysis and interpretation, Review of the manuscript & Editing. All authors read and approved the final manuscript. All members of the expert panel gave consent to have their names listed in the publication.\u201dAdditionally, the original version of this Article contained an error in Affiliation 14, which was incorrectly given as: \u201cEpitech, Paris, France\u201d. The correct affiliation is: \u201cEPITA, LRE MNSHS, Paris, France\u201d.The original Article has been corrected."}
{"text": "The authors regret that in the Acknowledgements section, the fund number for the National College Student Innovation Training Program was incomplete. The correct fund number for the National College Student Innovation Training Program is 202110879021.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Ghule  RSC Advances article following an institutional investigation carried out by RMIT University.The Royal Society of Chemistry, with the agreement of the authors, hereby wholly retracts this Fig. 1 and S5 both contain several identical vials representing different experiments. These figures were previously corrected before the Royal Society of Chemistry was aware that this paper was the subject of an institutional investigation.The investigation found that this paper \u201cbreached the Australian Code and RMIT Research Policy by not ensuring that conclusions are justified by the results and not responsibly disseminating research findings\u201d. A recommendation was given that this paper is retracted.Dr Namdev V. Ghule was fully responsible for the error that happened in the figures. All other authors, Prof. Sheshanath V. Bhosale and Dr Sidhanath V. Bhosale, are not responsible for this error.Signed: Namdev V. Ghule, Sheshanath V. Bhosale and Sidhanath V. BhosaleDate: 09/01/2023"}
{"text": "The Editor-in-Chief has retracted this article. After publication, the authors contacted the publisher to request a retraction because a wrong Trial Registration Number was used. After further investigation, concerns were raised about the western blots presented in the article. The authors did not supply raw data for these, or evidence of ethics approval on request. Therefore, the Editor-In-Chief no longer has confidence in the integrity of the data in this article.Authors have not responded to any correspondence from the editor about this retraction."}
{"text": "The following amendments have been suggested:22,36The surfactant-templated mesostructuring approach, introduced in ref. 21 and 25, allows for a more precise control of the intracrystalline mesoporosity introduced while retaining the main properties of the zeolites, including their microporosity, catalytic activity, and hydrothermal stability. For these reasons, surfactant-templated zeolites have been successfully commercialised.The preparation of mesostructured faujasites followed the general procedure introduced in ref. 25.18,25,44 our results demonstrate that TIPB conversion increases for all zeolites following their mesostructuring treatment.In agreement with previous reports,The authors would like to thank Professor Javier Garcia-Martinez and Dr Eric Li for the useful information provided regarding the synthesis of surfactant-templated zeolites.The reference numbers cited here correspond to those in the original paper.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors\u2019 attention by a concerned reader that certain of the western blotting assay data shown in Figs. 1C and 4C, and the tumor images shown in Fig. 5A were strikingly similar to data appearing in different form in other articles by different authors. Owing to the fact that the contentious data in the above article had already been published elsewhere, or were already under consideration for publication, prior to its submission to"}
{"text": "In addition, the authors independently contacted the Editorial Office to request that this paper be retracted owing to the fact that they had not obtained approval from the Ethics Committee of The Second Affiliated Hospital of Harbin Medical University to use the tissue samples, even though they had written that this study was approved by the Ethics Committee, and written informed consent had been provided by all patients enrolled in the research.Oncology Reports, and the authors' own admission of serious problems concerning the ethical nature of the study, the Editor has decided that this paper should be retracted from the Journal. The authors have agreed to the decision to retract the paper. The Editor apologizes to the readership for any inconvenience caused.Owing to the fact that the contentious data in the above article had already been published elsewhere, or were already under consideration for publication, prior to its submission to"}
{"text": "Pharmaceutical Biology, have retracted the following article:We, the Editors and Publisher of Authors: Xiaoyan Wang, Fang Xie, Xiaofeng Zhou, Ting Chen, Ye Xue, and Wei WangArticle: 18\u03b2-Glycyrrhetinic acid inhibits the apoptosis of cells infected with rotavirus SA11 via the Fas/FasL pathwayJournal: Pharmaceutical Biology10.1080/13880209.2021.1961821Volume 59; 2021; Pages 1096\u20131103; DOI: The authors noticed that some of the graphs and controls in Figure 3A and Figure 4A were similar. Upon further investigation, the authors realised they had made errors when creating the graphs and figures, leading to inconsistent results. In view of these problems, the authors contacted the journal to request a retraction.We have been informed in our decision-making by our policy on publishing ethics and integrity and the COPE guidelines on retractions.The retracted article will remain online to maintain the scholarly record, but it will be digitally watermarked on each page as \u201cRetracted\u201d."}
{"text": "RSC Advances article due to concerns with the reliability of the data in the published article.The Royal Society of Chemistry, with the agreement of the named authors, hereby wholly retracts this 3O4 XRD pattern in the region \u223c7\u201312 theta, and also within the CMC-g-MB XRD pattern in the region \u223c7\u201310 theta. An independent expert was consulted who was not satisfied with the explanation provided by the authors. The authors provided replacement XRD data, however upon review, the expert found that the new data for both Fe3O4 and CMC-g-MB appeared very different from the original manuscript.In Fig. 1F, there are unexpected similarities within the baseline of the Feii) and CMC-g-MB-HNO3 appear to be identical in the region of \u223c12\u201360 theta, but differ in the region below 12 theta. The expert was not satisfied with the authors\u2019 explanation and concluded that there was some degree of manipulation to try and make the two XRD patterns appear to be different. The authors provided replacement XRD patterns, but the expert concluded that they were very different from those presented in the original manuscript and would affect the original discussion in the manuscript.The XRD patterns presented in Fig. 8A for CMC-g-MB-Co(The 0 min and 5 min XPS spectra in Fig. S3B are identical in the regions above 102 eV, and below \u223c97 eV, but differ in the region of 97\u2013102 eV. Upon a vertical compression, the region of 97\u2013102 eV of the 5 min spectrum is also identical to the same region of the 15 min spectrum. The authors admitted that the 5 min spectrum was computer-generated to show the expected/desired result that they would then confirm experimentally and was not intended to be used in the article. The authors carried out the XPS measurements for CMC-g-MB treated with 0, 5 and 15 min of RF plasma again, and requested to publish the replacement data. However, the expert was not satisfied with the response and raised additional concerns regarding the reliability of the raw data provided by the authors.Furthermore, after analysing the raw data txt files and Origin files provided by the authors for Fig. 1F, 8A and S3B, the expert found that the numbers in the raw data txt files did not match the numbers given in the Origin files. The expert therefore was not satisfied that the raw data provided by the authors was reliable.Given the significance of the concerns about the validity of the data in the published paper and the raw data, the findings presented in this paper are no longer reliable.The other authors were contacted but did not respond.Signed: Rui Hu, Masaaki NagatsuDate: 3rd November 2022RSC AdvancesRetraction endorsed by Laura Fisher, Executive Editor,"}
{"text": "Microbiology Resource Announcements (MRA) are issuing this Expression of Concern regarding the following publication:The American Society for Microbiology (ASM) and Campylobacter coli bacteriophage CAM-P21. Microbiol Resour Announc 10:e00223-21. https://doi.org/10.1128/MRA.00223-21.Huang H-H, Zhang Y, Asoshima N, Duc HM, Sato J, Masuda Y, Honjoh K-I, Miyamoto T. 2021. Complete genome sequence of Campylobacter phage CAM-P21 with GenBank accession number MW462221 are as follows:The sequence does not include the three universal features of myoviruses: capsid biosynthetic proteins, packaging proteins , and lysis proteins.QRW43453 is a virion morphogenesis protein, as stated in the paper.HHpred analysis of the sequence showed no evidence that the protein submitted under NCBI accession number MRA was notified by a reader that sequence data reported in this paper are potentially inaccurate/incomplete. The concerns regarding ASM sent an inquiry to the authors and requested a response along with the original, underlying data regarding these concerns. ASM has not received a response addressing the concerns with the published data. This Expression of Concern is issued pending the authors\u2019 response and will be updated accordingly thereafter. If MRA and ASM do not receive the complete sequencing data and a thorough explanation to the above-mentioned concerns within 6\u2009months, then ASM will proceed with a Publisher\u2019s Retraction of this paper."}
{"text": "Cell Death and Disease 10.1038/s41419-019-1894-5, published online 09 September 2019Correction to: The original version of this article unfortunately contained a mistake. After the publication of this paper in Cell Death and Disease in 2019, the authors noted an error in Figure 2a, in that, the YAP blot for the SMMC-7721 cells was by mistake duplicated for the Bel-7402 cells. The correct YAP blot for Bel-7402 is now included in the figure given here. The authors would like to apologize for any inconvenience caused."}
{"text": "In the original publication , there wThe authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "The authors wish to bring to the readers' attention the following errors in the article by Jin Zhang and Shan Ju, \u2018Identifying genuine protein\u2013protein interactions within communities of gene co\u2010expression networks using a deconvolution method\u2019.In Section 5 Acknowledgements, one grant/award number was omitted. \u2018XBS\u2019 should be \u2018XBS1822\u2019."}
{"text": "The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper."}
{"text": "PROTOCOL: The impact of detention on the health of asylum seekers: A protocol for a systematic review\u2019 was inadvertently published in the incorrect, volume 13, Issue 1. The cover page of the PDF had the wrong date on it, and the publication date of the protocol says 2 January 2017, which is wrong. The correct publication date is 2 January 2014.The article listed below, intended for publication in Campbell Systematic Reviews, Volume 10, Issue 1, an issue entitled \u2018"}
{"text": "Bioscience Reports at the request of the authors due to technical reasons that they feel unable to address. This Retraction also takes place following receipt of a notification from a reader alerting the Editorial Office to similarities in figure panels across other published papers with no common authors. Figure panels of concern include 2C (common images across papers), 4F  and 5C/F (common images across papers). The authors are unable to correct the article and wish to retract the article. The Editor-in-Chief and Editorial Board agree with the Retraction.This article is being retracted from"}
{"text": "Journal of Healthcare Engineering has retracted the article titled \u201cEffectiveness and Prognosis: Drainage Skin-Bridge Sparing Surgery Combined with Fistulotomy vs. Fistulotomy Only in the Treatment of Anal Fistula\u201d [Fistula\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifiThe authors do not agree with the retraction."}
{"text": "The authors regret that the funding information in the Acknowledgements section of the original article was incorrectly shown.The correct funding information is as follows:\u00a0The present research was financially supported by: (iii) the European Union\u2019s Horizon 2020 research and innovation programme under the Marie Sk\u0142odowska-Curie grant no. 847413 and PMW programme of the Minister of Science and Higher Education in the years 2020\u20132024 no. 5005/H2020-MSCA-COFUND/2019/2.\u00a0The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "In the original publication , there wThe correct figures are attached below:The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. The original publication has also been updated."}
{"text": "Journal of Healthcare Engineering has retracted the article titled \u201cApplication of Intelligent Medical Equipment Management System Based on Internet of Things Technology\u201d [hnology\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifi"}
{"text": "In"}
{"text": "Retraction: Cancer Cell Int (2021) 21:54 10.1186/s12935-021-01749-7The Editors-in-Chief have retracted this article. After publication, the authors contacted the journal asking to retract the article because of issues with some experiments, but did not specify those issues. Upon further examination, unexpected similarities were found between western blots presented for different samples, for example panels 4f and 4g. The authors did not provide further comments or raw data. Therefore, the Editors-in-Chief have lost confidence in the data presented here. The authors have not explicitly stated whether they agree to this retraction notice."}
{"text": "In the published article, there were errors in affiliations 5\u201310.In affiliation 5, instead of \u201cBiomedical Research Networking Center in Infectious Diseases CIBERINF, Instituto de Salud Carlos III, Madrid, Spain,\u201d it should be \u201cBiomedical Research Networking Center in Infectious Diseases (CIBERINF), Instituto de Salud Carlos III, Madrid, Spain.\u201dIn affiliation 6, instead of \u201cClinical Genetics Department, Laboratori Cl\u00ednic Metropolitana Nord, Hospital Universitari Germans Trias i Pujol, Institut Universitari Germans Trias i Pujol (IGTP), Badalona, Spain,\u201d it should be \u201cClinical Genetics Department, Laboratori Cl\u00ednic Metropolitana Nord, Hospital Universitari Germans Trias i Pujol, Institut d'Investigaci\u00f3 en Ci\u00e8ncies de la Salut Germans Trias i Pujol (IGTP), Badalona, Spain.\u201dIn affiliation 7, instead of \u201cBiomedical Research Networking Center in Infectious Diseases CIBERINF, Instituto de Salud Carlos III, Madrid, Spain,\u201d it should be \u201cMicrobiology Department, Laboratori Cl\u00ednic Metropolitana Nord, Hospital Universitari Germans Trias i Pujol, Institut d'Investigaci\u00f3 en Ci\u00e8ncies de la Salut Germans Trias i Pujol (IGTP), Badalona, Spain.\u201dIn affiliation 8, instead of \u201cMicrobiology Department, Laboratori Cl\u00ednic Metropolitana Nord, Hospital Universitari Germans Trias i Pujol, Institut Universitari Germans Trias i Pujol (IGTP), Badalona, Spain,\u201d it should be \u201cBiomedical Research Networking Center in Respiratory Diseases (CIBERES), Instituto de Salud Carlos III, Madrid, Spain.\u201dIn affiliation 9, instead of \u201cBiomedical Research Networking Center in Respiratory Diseases CIBERES, Instituto de Salud Carlos III, Madrid, Spain,\u201d it should be \u201cDepartment of Genetics and Microbiology, Universitat Aut\u00f2noma de Barcelona, Cerdanyola, Spain.\u201dIn affiliation 10, instead of \u201cDepartment of Genetics and Microbiology, Universitat Aut\u00f2noma de Barcelona, Cerdanyola, Spain,\u201d it should be \u201cBiomedical Research Networking Center in Epidemiology and Public Health (CIBERESP), Instituto de Salud Carlos III, Madrid, Spain.\u201dThe authors apologize for these errors and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher."}
{"text": "Dear Editor,We have read the manuscript \u201cThe relationship between thiol-disulfide balance and idiopathic sudden sensorineural hearing loss\u201d in press in BJORLSecondly, the authors probably mistakenly stated that paraoxonase is a \u201clipid metabolism product\u201d and \u201cPON1 is an organophosphate\u201d. However, it is clear from the literature that paraoxonase is an enzyme which hydrolyses oxidised lipids.4Finally, the authors also state \u201cElevated PON levels are related to atherosclerosis\u201d. The reference given to justify this statement (citation 19 in Ref.These inaccuracies may seem minor to those not in the field; however, they are important and need correcting before they have time to spread.The authors declare no conflicts of interest."}
{"text": "The authors regret that they forgot to add the correct supplementary Table S2 in the supplementary data section. The correct supplementary Table S2 corresponds to unsaturated and saturated fatty acids of strains Marseille-P3761T and Marseille-P3195T instead of the phenotypic characteristics of the Marseille-P3761 and Marseille-P3195 strains obtained by using API ZYM. The phenotypic characteristics obtained by using API ZYM should be presented with those of API 50CH in Supplementary Table S1. The authors would like to apologize for the inconvenience caused.Supplementary file1 (DOCX 426 KB)Below is the link to the electronic supplementary material."}
{"text": "Journal of Healthcare Engineering has retracted the article titled \u201cMicroRNA-517c Functions as a Tumor Suppressor in Hepatocellular Carcinoma via Downregulation of KPNA2 and Inhibition of PI3K/AKT Pathway\u201d [Following an investigation conducted by the Hindawi Research Integrity team , signifi"}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive any reply. The Editor apologizes to the readership for any inconvenience caused.Given the multiple instances of overlapping data panels that have been identified in the compilation of the figures in this article, the Editor of"}
{"text": "Retraction Note: Nanoscale Research Letters (2022) 17:50 10.1186/s11671-022-03687-3The Editors-in-Chief have retracted this article because an investigation by the Publisher has shown evidence of authorship manipulation. The contributions of the listed authors cannot be confirmed and the Editors-in-Chief no longer have confidence in the content of the article. Ehsan Kianfar disagrees with this retraction. Nguyen Dinh Trung, Dinh Tran Ngoc Huy, Maria Jade Catalan Opulencia, Holya A. Lafta, Azher M. Abed, Hoang Van Thuc Master and Ali Thaeer Hammid have not responded to correspondence from the Publisher about this retraction. The Publisher was not able to find a current email address for Dmitry Olegovich Bokov and Kahramon Shomurodov."}
{"text": "Authors\u2019 affiliations and their roles in the supervisory activities of the Fukushima Health Management Survey as of fiscal year 2022 (in square brackets)* Affiliation 1 denotes the main affiliation"}
{"text": "Retraction note to: Mol Cancer 19, 85 (2020)https://doi.org/10.1186/s12943-020-01206-5The Editor-in-Chief has retracted this article. After publication, the authors alerted the journal that there were errors in Figs. 3b, 4j, S2g and S2h, resulting in overlap between images representing different treatment groups. The Editor-in-Chief therefore no longer has confidence in the presented data.Yiran Liang, Xiaojin Song, Yaming Li, Bing Chen, Wenjing Zhao, Lijuan Wang, Hanwen Zhang, Ying Liu, Dianwen Han, Ning Zhang, Yajie Wang, Fangzhou Ye, Dan Luo, Xiaoyan Li and Qifeng Yang agree to this retraction. Tingting Ma has not responded to any correspondence from the editor or publisher about this retraction."}
{"text": "Drosophila Species, Molecular Biology and Evolution, Volume 38, Issue 2, February 2021, Pages 437\u2013448, https://doi.org/10.1093/molbev/msaa232This is a correction to: Joanna F D Hagen, Cl\u00e1udia C Mendes, Shamma R Booth, Javier Figueras Jimenez, Kentaro M Tanaka, Franziska A Franke, Luis Baudouin-Gonzalez, Amber M Ridgway, Saad Arif, Maria D S Nunes, Alistair P McGregor, Unraveling the Genetic Basis for the Rapid Diversification of Male Genitalia between Sulf1 on chromosome arm 3R instead of Surf1 on chromosome arm 3L as reported.In the originally published version of this paper, the authors included re-analysis of phenotypic data from RNAi knockdown of genes reported in their previous publication, Tanaka et al. 2015 . The authors\u00a0have since discovered an error in one of the RNAi lines used, which meant that they actually targeted the gene Sulf1 from the text of the paper, Figure\u00a02 and supplementary files 5 and 6. The authors have also further clarified the genes that were first tested in Tanaka et\u00a0al., (2015) and those data reanalysed here in the context of new mapping and gene expression data.The paper has been corrected to remove these data for"}
{"text": "Journal of Healthcare Engineering has retracted the article titled \u201cAnalysis of the Effect of Nursing Intervention on Children with Respiratory Tract Infection Based on Comprehensive Nursing\u201d [Nursing\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifi"}
{"text": "Furthermore, they apologize to the readership for any inconvenience caused.After having consulted their original data, the authors have realized that these mice were correctly shown in the paper for the experiments portrayed in Fig. 7A; therefore, the corrected version of"}
{"text": "The Editor-in-Chief has retracted this article at the authors\u2019 request. After publication, the authors became aware that the KYSE180 cells used in this study were cross-contaminated. Further checks by the publisher identified high similarity between the KYSE180 200 and 300\u00a0\u03bcM middle images. Additionally, the authors have stated that the number of injected cells for the in vivo tumor growth assay provided in the Materials and methods is incorrect.All authors agree to this retraction."}
{"text": "The authors regret that the original version of our manuscript contained some inadvertent errors regarding the representative images in Figure"}
{"text": "Bioinformatics, Volume 38, Issue 10, 15 May 2022, https://doi.org/10.1093/bioinformatics/btac196This is a correction to: Manish Goel and Korbinian Schneeberger plotsr: visualizing structural similarities and rearrangements between multiple genomes, In the originally published version of the manuscript, there were errors in the details of affiliations for both authors. The affiliations should read:1Department of Genetics, Faculty of Biology, LMU Munich, Gro\u00dfhaderner Str. 2, 82152 Planegg-Martinsried, Germany and 2Department of Chromosome Biology, Max Planck Institute for Plant Breeding Research, Carl-von-Linn\u00e9-Weg 10, 50829 Cologne, Germany\u201d\u201cinstead of:1Faculty of Biology, LMU Munich, Planegg-Martinsried 82152, Germany and 2Department of Genetics, Faculty of Biology, LMU Munich, Germany\u201d.\u201cThe publisher apologizes for these errors. The errors have now been corrected within the article."}
{"text": "The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates. The Figure 3C Inhibitor NC panel seems to appear in other papers by unrelated authors, specifically as the Figure 2D Si-Tcf3#3 image from He et al. 2019 (doi: 10.1042/bsr20180369) and as the 143B/sh-VAV3+inhibitor panel of Figure 6E from Xiao et al. 2020 (doi: 10.18632/aging.103762)."}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors\u2019 attention by a concerned reader that certain of the cell migration and invasion assay data shown in Figs. 2C and 5C were strikingly similar to data appearing in different form in other articles by different authors. Owing to the fact that the contentious data in the above article had already been published elsewhere, or were already under consideration for publication, prior to its submission to"}
{"text": "Molecules several errors in our paper [A reader recently brought to the attention of the Editor-in-Chief and the Editorial Office of ur paper , with an1) Lane C without a loaded sample in  Lane C w1, Re, Rb1, Rb2, Rc and Rd in ginseng roots  were obtained using the HPLC gradient reported in Section 3.4 Quantification of Ginsenoside from Root Extracts, when in fact those conditions were used for the separation and quantification of the five ginsenosides Rg1, Re, Rb1, Rb2, and Rd, but not for ginsenoside Rc. As a result of a peer reviewer\u2019s comment that the amount of Rc seemed unduly high, the original HPLC traces were re-examined in 2014 and it was noted that in several chromatograms the Rc peak was not resolved, resulting in erroneously high integration values in the thesis. The experiments were re-run using a modified solvent gradient that isolated the ginsenoside Rc peaks and gave lower values consistent with the literature and those results are the ones reported in [(2) It was claimed that the HPLC ginsenoside quantification results in  did not (3) All co-authors of the article have read and agree with the content of this Correction, except for Dr A. J. Chen, who in communications with the corresponding author and the Editorial Office has insisted for personal reasons on a retraction of the article rather than a correction. However, having examined the provided copies of HPLC traces and laboratory notebooks and the explanations provided by the authors, the Editor in Chief is satisfied that a correction without Dr Chen\u2019s agreement and not a retraction is warranted for this paper.The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. The original publication has also been updated."}
{"text": "The authors would like to make a correction in a recently published paper .In the published publication, there was an error regarding the affiliation(s) for \u201cRamiro Garc\u00eda\u201d. In addition to affiliation(s) \u201c1\u201d, should be \u201cDepartment of Civil Engineering, Construction, School of Civil Engineering, Universidad Polit\u00e9cnica de Madrid, 28040 Madrid, Spain; garcia.ramiro@es.sika.com\u201d. The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "J Clin Invest. 2014;124(11):5057\u20135073. https://doi.org/10.1172/JCI71882Original citation: J Clin Invest. 2022;132(10):e161196. https://doi.org/10.1172/JCI161196Citation for this corrigendum: \u2013/\u2013 Fcrg\u2013/\u2013Dap12 sample image in \u2013/\u2013Fcrg panels. The authors have reviewed the original source data and determined that the incorrect\u2013RANKL, TKO sample was shown in \u2013/\u2013Fcrg image was shown in The authors recently became aware of errors in The authors regret the errors."}
{"text": "In \u201cThe Effects of a Virtual Reality\u2013Based Training Program for Adolescents With Disruptive Behavior Problems on Cognitive Distortions and Treatment Motivation: Protocol for a Multiple Baseline Single-Case Experimental Design\u201d :e33555) the authors noted an error.Child and Adolescent Psychiatry, Amsterdam UMC Location University of Amsterdam) was inadvertently omitted. The corrected list of authors and their affiliations now appear as follows:In the originally published article, one of the affiliations of author Ram\u00f3n J L Lindauer (1,2,3, MSc; Arne Popma1,3,4, MD, PhD; Ram\u00f3n J L Lindauer3,4,5, MD, PhD; Levi van Dam2,6, PhDRen\u00e9e E Klein Schaarsberg1Child and Adolescent Psychiatry & Psychosocial Care, Amsterdam UMC location Vrije Universiteit Amsterdam, Amsterdam, Netherlands2Dutch Innovation Network for Societal Youth Challenges, Garage2020, Amsterdam, Netherlands3Mental Health, Amsterdam Public Health, Amsterdam, Netherlands4Academic Center for Child and Adolescent Psychiatry, Levvel, Amsterdam, Netherlands5Child and Adolescent Psychiatry, Amsterdam UMC location University of Amsterdam, Amsterdam, Netherlands6Department of Child Development and Education, University of Amsterdam, Amsterdam, NetherlandsThe correction will appear in the online version of the paper on the JMIR Publications website on May 27, 2022, together with the publication of this correction notice. Because this was made after submission to PubMed, PubMed Central, and other full-text repositories, the corrected article has also been resubmitted to those repositories."}
{"text": "Retraction Note: BMC Complement Med Ther 20, 192 (2020)10.1186/s12906-020-02995-4The Editor has retracted this article. After publication, the authors became aware that the histology images in Fig.\u00a01\u00a0C were not representative, and requested a Correction. Further assessment of the data by the Journal identified the following concerns:In Fig.\u00a01D, there appears to be overlap between the NC and medium dose images.In Fig.\u00a03\u00a0F, there appears to be overlap between model control and low dose images.In Fig.\u00a03G, the resolution of the flow cytometry plots appears to be inconsistent. Specifically, the data point size in the medium group is larger than the other groups.Western blots in Fig.\u00a03\u00a0H are presented in unnatural-looking backgrounds, with straight vertical and horizontal edges on some of the bands.Western blots in Fig.\u00a03I appear to contain duplicated areas between the P38 and p-P38 images.The authors have provided some of the raw data to address these concerns, which contained further cases of overlap or did not support the presented results. Additionally, the authors have stated that part of the data were generated by a third party. The Editor therefore no longer has confidence in the data presented in this article.All authors have agreed to this retraction but not to the wording of this retraction notice."}
{"text": "We would like to update thecontent of"}
{"text": "The authors have retracted this article because it has been previously published by the same authors in a Chinese-language Journal . Shen-Yu"}
{"text": "In spite of its central importance for human beings, emotion is still one of the least studied subjects among the life sciences  or cortisone, oxytocin, or sex hormone. Oxytocin has been recently found to be the neuromodulator for love and attachment  oxytocin, reciprocally coupled with vasopressin and (lower) testosterone.In the paper titled \u201cRoles of Anxiety and Depression in Predicting Cardiovascular Disease Among Patients With Type 2 Diabetes Mellitus: A Machine Learning Approach,\u201d the authors Chu et al. tried to investigate the underlying neural mechanisms for the emotional problems that are related to cardiovascular diseases in a bio-psycho-social way.In the paper titled \u201cAffective Face Processing Modified by Different Taste,\u201d the author Liang et al. reported their studies about the cross-modal interaction between taste and emotional face search using two tastes (sweet and acid) to investigate the cross-modal interaction between taste and emotional face search and their underlying mechanisms.In the paper titled \u201cCollectively, these studies demonstrate that neurotransmitters play an important role in emotion. We hope that this special issue will stimulate interest in the field of basic emotion.FW, RH, FP, JY, and JH wrote the paper. All authors contributed to the article and approved the submitted version.The paper was supported by a grant from Foundation of Humanities and Arts from the Ministry of Education in China (19YJAZH083).The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher."}
{"text": "The authors regret that the funding information was not included in the acknowledgements in the original article. The following acknowledgements should have been included:This work was supported in part by the Engineering and Physical Science Research Council (EPSRC) through Engineering Fellowship for Growth\u2014PRINTSKIN (EP/M002527/1) and neuPRINTSKIN (EP/R029644/1) and EPSRC ORCA \u2013 Partnership Resource Fund Project MUSES (EP/R026173/1). In addition, this work received support from the European Union\u2019s Horizon 2020 Research and Innovation Programme (AQUASENSE Project) under the Marie Sk\u0142odowska-Curie grant agreement No: H2020-MSCA-ITN-2018-813680.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "RSC Advances article due to concerns with the reliability of the data.The Royal Society of Chemistry hereby wholly retracts this Many of the published western blot panels contain duplicating features between the backgrounds of different panels, indicating that they have been manipulated. For example, there are duplicating features between the backgrounds of the panels in Fig. 6E (c-myc/MCF-7) and Fig. 7B (SOX4/MDA-MB-231). There are also duplicating features between the backgrounds of the SOX4/MCF-7 and SOX4/MDA-MB-231 panels in Fig. 7B.Three of the bands shown in Fig. 7D  also contain duplicating features, indicating that they have been artificially generated. There are also repeating fragments in the backgrounds of the two panels.The authors were asked to provide the raw data for this article, but did not respond. Given the significance of the concerns about the validity of the data, and the lack of raw data, the findings presented in this article are not reliable.The authors were informed but have not responded to any correspondence regarding the retraction.RSC AdvancesSigned: Laura Fisher, Executive Editor, Date: 18th August 2022"}
{"text": "Following the publication of this article , concern\u25cb Fig 7 (right panel), lanes 1 and 3.\u25cb Fig 10A, lanes 2 and 4, and lanes 5 and 7 flipped horizontally.The following data appear similar despite representing different conditions:\u25cb Fig 1, between lanes 1\u20132.\u25cb Fig 3 (lower left panel), between lanes 1\u20132.\u25cb Fig 7 (right panel), between lanes 2\u20133, 3\u20134 and 6\u20137.\u25cb Fig 9 (right panel), between lanes 1\u20132.\u25cb Fig 10A, between lanes 4\u20135.There appear to be vertical discontinuities in the following figures when colour levels are adjusted:The corresponding author stated that the raw image data underlying the above figures are no longer available. They acknowledged that the presented results are merged from multiple experiments, and stated that splice lines are clearly visible and were intentional.In relation to the concerns in Figs 7 and 10, the corresponding author acknowledged that the data in the lanes listed above appear similar, but asserted that they are not identical. In the absence of raw image data, the editors remain concerned about the integrity of these figures.PLOS ONE Editors retract this article.In light of the concerns affecting multiple figure panels that question the integrity of these data, the AYS did not agree with the retraction and stands by the article\u2019s findings. All other authors either did not respond directly or could not be reached."}
{"text": "Journal of Healthcare Engineering has retracted the article titled \u201cEfficacy and Safety of Temozolomide Combined with Radiotherapy in the Treatment of Malignant Glioma\u201d [ Glioma\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifi"}
{"text": "In \u201cAge- and Sex-Specific Differences in Multimorbidity Patterns and Temporal Trends on Assessing Hospital Discharge Records in Southwest China: Network-Based Study\u201d : e27146) the authors noted one error.In the originally published paper, the denominator of Equation 2 was incorrect and should have been expressed as a square root.In the corrected version of the paper, the denominator of Equation 2 has been revised to a square root and is provided below. The calculations in the original publication were according to the correct version of Equation 2. The error in Equation 2 did not influence the results of the originally published paper.The correction will appear in the online version of the paper on the JMIR Publications website on June 16, 2022, together with the publication of this correction notice. Because this was made after submission to PubMed, PubMed Central, and other full-text repositories, the corrected article has also been resubmitted to those repositories."}
{"text": "G. P\u00e9rez-Garc\u00eda et al., RSC Adv., 2015, 5, 23255\u201323260.Correction for \u2018Porous monoliths synthesized  The authors regret that there was an error in the results and discussion section of the original article. On page 23257, the text read, \u201cThe surfactant employed here was sorbitan monooleate\u201d. This should have read, \u201cThe surfactant employed here was sorbitan stearate\u201d.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors\u2019 attention by a concerned reader that certain of the data shown for the cell migration and invasion assays in Figs. 2B and 4B were strikingly similar to data appearing in different form in other articles by different authors. Owing to the fact that the contentious data in the above article had already been published elsewhere, or were already under consideration for publication, prior to its submission to"}
{"text": "In the original publication Figs. 1, 2 and 3 are incorrectly published, the correct Figs."}
{"text": "Experimental and Molecular Medicine 10.1038/emm.2017.98, published online 21 July 2017Retraction to: 1Figures 3a and 3b overlap with Figures 2b and 2c in Ref. 2Figure 3b overlaps with Figure 2C in Ref. The authors have retracted this article because of issues with two of the figures. Specifically:All authors agree with this retraction."}
{"text": "Monoclonal antibodies targeting the anti-SARS-CoV-2 spike (S) protein are prescribed in high-income countries to prevent severe disease in at-risk patients. Although studies report efficacy as between 50\u201385% , data confirm that immunocompromised patients with long-term SARS-CoV-2 replication are particularly susceptible to resistance and transmissible variant emergence  as well as their specific regional context .MH and AC wrote the first manuscript draft. All authors critically reviewed the manuscript, validated the final version, and agreed to be accountable for the content of the work.The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher."}
{"text": "Chlamydomonas telomeric DNA\u2019 by Aparna Bansal et al., RSC Adv., 2022, 12, 15918\u201315924, https://doi.org/10.1039/D2RA00861K.Correction for \u2018A novel G\u00b7G\u00b7T non-conventional intramolecular triplex formed by the double repeat sequence of  The authors regret that an incorrect version of The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Retraction Note: J Exp Clin Cancer Res 39, 134 (2020)https://doi.org/10.1186/s13046-020-01626-7The Editor-in-Chief has retracted this article. After publication it was noted that there was an overlap between the images in figures 3F, 3G and 8f. Furthermore irregularities have also been detected in figure 8C. The Editor-in-Chief has therefore lost confidence in the reliability of the results presented in this article. All authors agree to this retraction."}
{"text": "It has been updated as"}
{"text": "Computational and Mathematical Methods in Medicine has retracted the article titled \u201cEffectiveness of Home Care Interventions in Patients with Moderate to Severe Craniocerebral Injury Combined with Epilepsy\u201d [pilepsy\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifi"}
{"text": "Clinical Case Reports, the authors have updated the content in Acknowledgment section as follows: \u201cAll authors would like to include their sincere thanks to Dr. Jihad Nassar, an otolaryngology consultant at King Abdulaziz Medical City\u2014National Guard Hospital in Riyadh, for his help in caring for the patient and his suggestions regarding the manuscript writing.\u201dIn the article entitled \u201cHyaluronic acid augmentation pharyngoplasty complicated by retropharyngeal abscess and Grisel syndrome: Case report and literature review\u201d"}
{"text": "Computational and Mathematical Methods in Medicine has retracted the article titled \u201cEvaluation of the Effect of Comprehensive Nursing in Psychotherapy of Patients with Depression\u201d [ression\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifi"}
{"text": "DistincIn summary, significant species variance was revealed by our study,The authors declare no competing interests."}
{"text": "The animal ethics statement was missing from this paper. The following statement should be included: \u201cThe animal use protocol listed in this paper was reviewed and ethical approval for the study was given by the Laboratory Animal Center of Zhejiang University.\u201d"}
{"text": "The authors regret that the citations to references 15, 27 and 28 in the sub-section \u201cVariable fluorescence bandpass hyperspectral imaging of Hep G2 cells with correlated scanning electrochemical microscopy\u201d are incorrect. The references should be given as 17, 37 and 42 and should be cited on page 2399.Reference 42 was not included in the original article and is listed below.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers.ReferencesElectrochemical Methods for Neuroscience, 2007, 1, 353\u2013372.42. A. Schulte and W. Schuhmann,"}
{"text": "In view of the fact that these data had already apparently been published previously, the Editor of Experimental and Therapeutic Medicine has decided that this paper should be retracted from the Journal. The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors\u2019 attention by a concerned reader that the western blotting data shown in Fig. 3B were strikingly similar to data appearing in different form in other articles written by different authors at different research institutes that had either already been published elsewhere prior to the submission of this paper to"}
{"text": "We thank International Science Editing (Competing interestsThe authors declare that they have no competing interests."}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Owing to the fact that the contentious data in the above article had already been published prior to its submission to"}
{"text": "In the published publication , there wDavide Bassani and Stefano Moro * Molecular Modeling Section (MMS), Department of Pharmaceutical and Pharmacological Sciences, University of Padova, Via Marzolo 5, 35131 Padova, Italy; davide.bassani@roche.com* Correspondence: stefano.moro@unipd.itThe authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "Cell Death Discovery 10.1038/s41420-022-00895-9, published online 04 May 2022Retraction to: The authors have retracted this article because the authors noticed a mistake in panel I of Figure 1. The incorrect raw data of the key candidate genes, including PDGFRB and CST3, was used to create the heat map. The authors no longer have confidence in the accuracy of the results presented in this article. None of the authors have responded to any correspondence from the editor about this retraction."}
{"text": "First, the \u03b1-tubulin bands featured in Fig. 3B on p. 68 were inadvertently included as the control western blots for the HCT116 cell line in Oncology Letters for granting them this opportunity to publish a corrigendum, and apologize to the readership for any inconvenience caused.The authors were able to re-examine their original data, and have recognized how these errors occurred. The corrected versions of"}
{"text": "Chem. Chem. Phys., 2023, 25, 17596\u201317608, https://doi.org/10.1039/D3CP00479A.Correction for \u2018Limitations of non-polarizable force fields in describing anion binding poses in non-polar synthetic hosts\u2019 by David Seiferth  The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Retraction Note: BMC Cancer 13, 527 (2013)10.1186/1471-2407-13-527The Editor has retracted this article because it appears that some of the text and figures have been previously published by some of the same authors. Specifically:there is substantial text overlap with results section in Figure 2B appears to present the same data as Fig.\u00a01C in [It appears the same FACS plots have been presented in Fig.\u00a03B  and control) as in Fig.\u00a04A in Figure 3C (sifn and Poly(I:C) ) and 3D appear to show the same images as those published previously in  in Fig.\u00a0Author Yu-Yin Xu does not agree to this retraction. None of the other authors have responded to any correspondence from the editor or publisher about this retraction"}
{"text": "In \u201cEfficacy, Benefits, and Harms of a Self-management App in a Swedish Trauma-Exposed Community Sample (PTSD Coach): Randomized Controlled Trial\u201d :e31419) the authors noted one error.In Table 1, the number of participants who screened positive for PTSD in the App Access condition was incorrectly published as \"38 (42.7%).\" This has been changed to \"51 (57.3%).\"The correction will appear in the online version of the paper on the JMIR Publications website on February 28, 2023, together with the publication of this correction notice. Because this was made after submission to PubMed, PubMed Central, and other full-text repositories, the corrected article has also been resubmitted to those repositories."}
{"text": "Retraction Note: Naunyn\u2013Schmiedeberg's Archives of Pharmacology (2023) 396:1931\u20131942\u00a0https://doi.org/10.1007/s00210-023\u201302449-xThe Editor-in-Chief has retracted this article. After publication, concerns were raised regarding some of the images in the figures. Specifically:Figure\u00a05c and e appear to overlap with rotation.In Fig.\u00a07a, b, d and e, the images appear to contain repeated patterns.The authors have provided the raw data to address these concerns; however, the same issues were observed in the original images. The Editor-in-Chief therefore no longer has confidence in the presented data.Sousou I. Ali and Nahla N. Younis do not agree to this retraction. Mohamed A. Shaheen, Mohamed Mahrous and Mohamed M. Elseweidy have not explicitly stated whether they agree to this retraction."}
{"text": "There was an error in the original publication . The ethA correction has been made to Section 2.1. Participants, lines 12\u201314:The ethical standards contained in the Declaration of Helsinki were followed in this study, and this study was approved by the ethics committee of the Polytechnic Institute of Viana do Castelo (IPVC-ESDL180417).The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "This is a peer-review report submitted for the paper \u201cTechnologies to Support Assessment of Movement During Video Consultations: Exploratory Study.\u201dThank you for taking the time to submit this paper . It is a1. Please consider that movement at least has four basic parameters, including force, range of motion/distance, rate (velocity/acceleration), and endurance (repeats until the mover is fatigued). I think authors could talk more about the shortcomings of their methods for comprehensive assessments of the parametric abilities of movements.2. To further discuss the limitations of your study, please note that in resource-limited environments and developing countries, these results cannot be generalized.3. Please correct the spelling of \u201cCINHAL\u201d.4. Please explain why authors selected a time limit (since 2016) for their literature search.5. The specification of products/instruments should include details ."}
{"text": "Retraction Note: Hernia (2023) 27:1195\u20131202 10.1007/s10029-023-02765-4The authors have retracted this paper because they did not secure ethics approval before conducting post-operative follow-ups with the participants in this study. All authors agree to this retraction."}
{"text": "Nature Medicine 10.1038/s41591-023-02317-4. Published online 24 April 2023.Correction to: In the version of this article initially published, the STRATIFY data also included cohort data from the ESTRA consortium, though this was not acknowledged in the author list and the section in Methods on the Stratify dataset. The Methods are now updated, and the author list is amended to combine the STRATIFY and ESTRA consortium names and to include the following authors: Marina Bobou, M. John Broulidakis, Betteke Maria van Noort, Zuo Zhang, Lauren Robinson, Nilakshi Vaidya, Jeanne Winterer, Yuning Zhang, Sinead King, Herv\u00e9 Lema\u00eetre, Ulrike Schmidt, Julia Sinclair, Argyris Stringaris and Sylvane Desrivi\u00e8res. The STRATIFY and ESTRA consortia are now combined to list Marina Bobou, M. John Broulidakis, Betteke Maria van Noort, Zuo Zhang, Lauren Robinson, Nilakshi Vaidya, Jeanne Winterer, Yuning Zhang, Sinead King, Gareth J. Barker, Arun L. W. Bokde, Herv\u00e9 Lema\u00eetre, Frauke Nees, Dimitri Papadopoulos Orfanos, Ulrike Schmidt, Julia Sinclair, Argyris Stringaris, Henrik Walter, Robert Whelan, Sylvane Desrivi\u00e8res and Gunter Schumann as members, and the IMAGEN consortium is updated to also include Sylvane Desrivi\u00e8res. Affiliations, author contributions and acknowledgements have been updated to reflect the new authorship, and all changes have been made in the HTML and PDF versions of the article."}
{"text": "The revised version of"}
{"text": "In view of the fact that these data had already apparently been published previously, the Editor of Experimental and Therapeutic Medicine has decided that this paper should be retracted from the Journal. The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors\u2019 attention by a concerned reader that the western blotting data shown in Fig. 2, 3 and 5, and the Transwell migration assay data in Fig. 4, were strikingly similar to data appearing in different form in other articles written by different authors at different research institutes that had either already been published elsewhere prior to the submission of this paper to"}
{"text": "Retraction: Parasites & Vectors (2017) 10:303 10.1186/s13071-017-2239-9The Editor-in-Chief has retracted this article. After publication, concerns were raised regarding western blot similarities in Figs. 5B  and 6C . Additional checks by the Publisher have found a number of unexpected breaks in the western blot backgrounds in Figs. 3C\u2013F and 5B.The Editor-in-Chief therefore no longer has confidence in the presented data.Sujata Kumari agrees to this retraction. Sudha Verma does not agree to this retraction. None of the other authors have responded to any correspondence from the editor or publisher about this retraction."}
{"text": "In \u201cExperiences of Complex Patients With Telemonitoring in a Nurse-Led Model of Care: Multimethod Feasibility Study\u201d :e22118) the authors made one addition.The following text has been added as an Acknowledgment:This research was made possible by the funding support from a Canadian Institutes of Health Research Personalized Health Catalyst Grant (Funding Reference Number 155443).The correction will appear in the online version of the paper on the JMIR Publications website on October 24, 2023 together with the publication of this correction notice. Because this was made after submission to PubMed, PubMed Central, and other full-text repositories, the corrected article has also been resubmitted to those repositories."}
{"text": "This infographic highlights a recently published paper titled \u201cA Holistic Perspective of the Societal Relevance of Beef Production and Its Impacts On Climate Change\u201d . A key c"}
{"text": "J Manag Care Spec Pharm. 2019;25(12):1306-08.This article has been corrected. Please see Spinal Muscular Atrophy Therapies: ICER Grounds the Price to Value Conversation in Facts.J Manag Care Spec Pharm. 2019;25(12):1306-08.Starner CI, Gleason PP. The authors would like to make the following corrections to the above article:Page 1306, right column, the following sentence should be deleted: \u201cAccording to the ICER report, \u2018By May 2018, caregivers reported all 25 (100%) had achieved sitting without support, 22/25 (85%) of children had achieved walking with assistance, and 17/25 (68%) had achieved walking alone\u2019.\u201dPage 1307, left side, end of first paragraph: \u201c27.1 months\u201d should be changed to \u201c24 months.\u201dWhile the authors regret these errors, they do not affect the conclusions of the article."}
{"text": "Correction to: Acta Neurochirurgicahttps://doi.org/10.1007/s00701-022-05389-2The article \"The value of intraoperative indocyanine green angiography in microvascular decompression for hemifacial spasm to avoid brainstem ischemia\" written by Ahmed Al Menabbawy et. al, was originally published online October 25, 2022 has an error.At the last sentences of paragraph 2 in the discussion; \u201cAlthough most of the compressions are caused by arterial conflicting vessels , we had 2 cases of pure venous compressions, and some series reported up to 4.5% of cases with venous compression as the conflicting vessel \u201c.The mistake is that we had only one pure venous compression and not two. The second case with venous compression was actually combined with vertebral artery and was not pure. So, the correct statement should be; \u201cAlthough most of the compressions are caused by arterial conflicting vessels , we had only one case of pure venous compression and another case with venous compression combined with vertebral artery compression, and some series reported up to 4.5% of cases with venous compression as the conflicting vessel.\u201dThe original version of this article is corrected."}
{"text": "This study compared the efficacy of three commercial oral rehydration solutions (ORS) for restoring fluid and electrolyte balance, after exercise-induced dehydration.N\u2009=\u200920; \u2640\u2009=\u20093; age \u223c27 y, 2peak \u223c52\u2005ml/kg/min) completed three randomised, counterbalanced trials whereby intermittent exercise in the heat  induced \u223c2.5% dehydration. Subsequently, participants rehydrated  with a glucose-based (G-ORS), sugar-free (Z-ORS) or amino acid-based sugar-free (AA-ORS) ORS of varying electrolyte composition. Urine output was measured hourly and capillary blood samples collected pre-exercise, 0, 2 and 5\u2005h post-exercise. Sodium, potassium, and chloride concentrations in urine, sweat, and blood were determined.Healthy, active participants (P\u2009\u2264\u20090.010). Only AA-ORS achieved positive sodium and chloride balance post-exercise, which were greater for AA-ORS than G-ORS and Z-ORS (P\u2009\u2264\u20090.006), as well as for G-ORS than Z-ORS (P\u2009\u2264\u20090.007) from 1 to 5\u2005h.Net fluid balance peaked at 4\u2005h and was greater in AA-ORS (141\u2009\u00b1\u2009155\u2005ml) and G-ORS (101\u2009\u00b1\u2009195\u2005ml) than Z-ORS (\u221247\u2009\u00b1\u2009208\u2005ml; when provided in a volume equivalent to 125% of exercise-induced fluid loss, AA-ORS produced comparable/superior fluid balance and superior sodium/chloride balance responses to popular glucose-based and sugar-free ORS. Typically, fluid intake during exercise does not keep pace with fluid lost through sweating , 2, meanFor complete and rapid rehydration between exercise bouts the most important nutritional factor is beverage volume, with research demonstrating the volume ingested must be more than that lost to account for ongoing fluid losses in the post-exercise period , 11. SecFurthermore, manipulating the carbohydrate and protein/amino acid composition of a beverage might enhance post-exercise rehydration . PreviouExercise-induced dehydration without fluid replacement produces hypertonic hypovolaemia or intracellular dehydration . This ocIt is well established that glucose can facilitate water and sodium absorption across the intestine through the cotransporter protein SLC5A1 . A varieInterestingly, recommended ORS sodium content (\u223c75\u2005mmol/L) is consistent with beverages shown to optimise post-exercise rehydration , 13. As Therefore, the purpose of the present study was to compare the post-exercise rehydration efficacy of a novel amino acid-based ORS developed using HydroActive Technology\u2122  (AA-ORS) with two established ORS formulations; Pedialyte Classic\u00ae  and Pedialyte Zero\u00ae . On the basis of superior beverage hydration index outcomes when comparing AA-ORS to G-ORS and other sugar-based commercial beverages in well-hydrated people , we hypo2.2.1.All experimental procedures were approved by the Loughborough University Ethics Approvals Human Participants Sub-Committee (LEON 6013). Participants were fully informed of the risks and discomforts associated with all experimental trials before completing a health screen questionnaire and providing written, informed consent.2.2.N\u2009=\u200917 male, N\u2009=\u20093 female, age 27\u2009\u00b1\u20095 y, height 1.76\u2009\u00b1\u20090.09\u2005m, body mass 74.6\u2009\u00b1\u200911.7\u2005kg, 2peak 52\u2009\u00b1\u200915\u2005ml/kg/min, body fat 13.9\u2009\u00b1\u20093.7%) participated in this study. Participants did not have a history of renal, haematological, or musculoskeletal abnormalities. All participants were living in the U.K. during the months of the study and confirmed that they had not completed exercise training in hot conditions.Twenty healthy, non-heat acclimated, recreationally active individuals .2.4.2peak) and peak power output (Wpeak) were determined using an incremental step test to exhaustion. Exercise began at a freely chosen pedal cadence at a workload of 95 W and increased by 35 W every 3\u2005min until volitional exhaustion, despite strong verbal encouragement. Expired gases were collected into a Douglas bag for the final 45\u201360 s to determine 2peak. Expired gas was analysed for O2 and CO2 content , volume  and temperature .During the preliminary visit, body mass , height, and body fat  were ob2.5.Participants arrived at the laboratory in the morning (time standardised within participant to limit the effects of circadian variation). Participants consumed a standardised breakfast 1.5\u2005h before arrival, consisting of cereal bars totalling 1 g/kg body mass carbohydrate and orange juice mixed with water to provide 0.5 g/kg body mass carbohydrate in a total of 500\u2005ml fluid. The food and fluid were provided to ensure adequate energy availability and pre-trial hydration in anticipation of the exercise protocol. In the 24\u2005h prior to the first experimental trial, participants completed a weighed diet record (food and fluid) using food scales accurate to 1\u2005g and consumed a minimum fluid intake of 40\u2005ml/kg body mass, replicating this food and fluid intake in the 24\u2005h before subsequent trials. Additionally, participants refrained from strenuous physical activity in the 48\u2005h before trials and refrained from alcohol intake in the 24\u2005h before trials. For the measurement of body core temperature during trials, participants ingested a radio-telemetry pill  \u223c10\u201312\u2005h before arrival . Adherence to all pre-trial requirements was verbally confirmed before each trial.2.6.On arrival at the laboratory, and after 10\u2005min seated rest, a small incision was made in a fingertip using a lancet and a 150 uL capillary blood sample was collected into a heparinised capillary tube . Sweat patches  were affixed to the right forearm and right scapula , 43, aft2.7.Participants were dehydrated by intermittent cycling at \u223c50% Wpeak in an environmental chamber maintained at 36.3\u2009\u00b1\u20090.2\u00b0C and 52.5\u2009\u00b1\u20091.0%, until 2.2% of their pre-trial body mass was lost. The total body mass loss target was 2.5% and it was estimated participants would lose the additional 0.3% in the 30\u2005min post-exercise cool down. Participants cycled for 10\u2005min, followed by 5\u2005min rest in the chamber, during which they towel dried and nude body mass was measured. Rate of body mass loss was used to adjust the duration of the final stage to ensure participant body mass loss was as close to 2.2% as possible. In the final min of each exercise stage, rating of perceived exertion [RPE ], thirst2.8.The rehydration phase lasted 5\u2005h and participants consumed 125% of the total body mass losses during dehydration in four even aliquots at hourly intervals . Participants were required to consume the entire volume of each aliquot within 10\u2005min. Participants rested quietly seated in the laboratory for this 5\u2005h, except for urine collection and nude body mass measurements. In the final 5\u2005min of each hour, ambient temperature and relative humidity, as well as GI comfort and thirst were recorded, before participants voided their bladder and had nude body mass measured on the hour. Following the consumption of the second drink (1\u2005h 10\u2005min), participants were provided with a lunch of cereal bars (1.5\u2005kg/body mass of carbohydrate), which they consumed within 10\u2005min. This food was provided due to the extended duration of the protocol and for greater ecological validity, as it is unlikely athletes would restrict food in the 5\u2005h post-exercise in real-world scenarios. Additional fingertip capillary blood samples were collected after 10\u2005min seated rest at 2\u2005h and 5\u2005h of the rehydration phase.2.9.The composition of the ORS beverages used are presented in 2.10.A blood gas analyser  was used for the immediate determination of blood sodium, potassium, and chloride concentration in capillary blood samples. For all urine samples, mass to the nearest 0.1\u2005g, with 1\u2005g assumed to equal 1\u2005ml  and specific gravity to the nearest 0.001  were immediately determined and an aliquot was frozen at \u221280\u00b0C for later analysis. ORS, urine and sweat samples were analysed for sodium and potassium concentrations by flame photometry  and chloride concentration by coulometric titration . For beverage electrolyte concentrations, a sample of eight different beverages for each of the three beverages were measured, with the mean values for each used in calculations of electrolyte balance. Sweat sodium and potassium , as well2.11.N\u2009=\u2009100 - (100 x [CumUON / (CumDVN\u2009+\u2009CumFWN)]Fluid retention at time point N\u2009=\u2009-\u2009+\u2009CumDVN\u2009+\u2009CumFWN - CumUONNFB at time point N\u2009=\u2009-SE\u2009+\u2009CumDEN\u2009\u2212\u2009CumUENElectrolyte balance at time point 4h] / 240}Time to full fluid balance recovery\u2009=\u2009 / {[ - NFBKey: CumUO is cumulative urine output (mL); CumDV is cumulative drink volume (mL); CumFW (mL) is cumulative food water; NFB is the net fluid balance (mL); SL is the total sweat loss (L) calculated from body mass loss from pre-exercise to 0\u2005h; BM is body mass (kg); SE is sweat electrolyte loss (mmol); CumDE is cumulative drink electrolyte concentration (mmol); CumUE is cumulative urine electrolyte concentration (mmol). Superscript denotes the timepoint of measure.2.12.t-tests or Wilcoxon Signed-Rank tests, as appropriate. The familywise error rate was controlled using the Holm-Bonferroni correction. Cochran's Q test was utilized to compare differences in hydration recovery between beverages (each participant treated as randomized block). Pairwise comparisons were then made using a permutation test with a False Disovery Rate correction applied to the P-values  based on a medium effect for net fluid balance across the three trials (\u03b7p2\u2009=\u20090.07), an \u03b1 of 0.05 and a \u03b2 of 0.2 and a correlation between repeated measures of 0.66, determined from previous studies from our research group examining the effect of amino acid containing beverage to amino-acid-free beverages . All data were initially checked for normality of distribution prior to analysis using two-factor or one-factor repeated-measures ANOVA. Where the assumption of sphericity was violated, the Greenhouse-Geisser correction was used. Where significant interaction (two-way ANOVA) or main (one-way ANOVA) effects were observed, differences between trials were explored using post-hoc paired P-values , 48. Alleverages , 25\u201327. , IBM. Al3.3.1.P\u2009=\u20090.378 and P\u2009=\u20090.432, respectively) or rest .There were no differences in room temperature or relative humidity  between 3.2.P\u2009=\u20090.214), mean thermal sensation (P\u2009=\u20090.275), mean thirst (P\u2009=\u20090.656), mean core body temperature (P\u2009=\u20090.106) or the total exercise duration required to produce the 2.2% decrease in body mass (P\u2009=\u20090.483). Total body mass loss in kg (P\u2009=\u20090.402), % body mass loss (P\u2009=\u20090.399) and urine output during the dehydration phase (P\u2009=\u20090.582) were also not different between trials. Therefore, the volume of beverage consumed during trials was not different in total  or for each aliquot . The meal participants consumed at 1\u2005h 10\u2005min was identical and contained a small amount of water amounting to 22\u2009\u00b1\u20095\u2005ml . Finally, there were no significant differences between trials for total sweat losses of sodium (P\u2009=\u20090.360), potassium (P\u2009=\u20090.776) or chloride (P\u2009=\u20090.140) during exercise.Relevant variables for the dehydration phase of the study are presented in 3.3.P\u2009=\u20090.214; P\u2009=\u20090.580; P\u2009<\u20090.001), increasing following the dehydration phase before decreasing over the rehydration phase.There were no interaction effects for thirst (3.4.P\u2009<\u20090.001) for urine output, with less urine output in AA-ORS and G-ORS compared with Z-ORS at 4\u2005h  and 5\u2005h . There was a time x trial interaction effect for urine specific gravity (P\u2009<\u20090.001), which increased following dehydration in all trials and remained elevated until 3\u2005h in G-ORS (P\u2009\u2264\u20090.024) and AA-ORS (P\u2009\u2264\u20090.018), and until 2\u2005h in Z-ORS (P\u2009\u2264\u20090.018). Additionally, urine specific gravity was lower than baseline at 4\u2005h and 5\u2005h in Z-ORS . There was a time x trial interaction effect (P\u2009<\u20090.001) for fluid retention  and 5\u2005h . There were interaction effects for cumulative sodium (P\u2009<\u20090.001), potassium (P\u2009=\u20090.002) and chloride (P\u2009<\u20090.001) losses in urine (P\u2009\u2264\u20090.014) and in AA-ORS compared to G-ORS from 3 to 5\u2005h (P\u2009\u2264\u20090.006), with no differences between G-ORS and Z-ORS (P\u2009\u2265\u20090.064). Cumulative potassium losses were greater in G-ORS compared to Z-ORS at 1\u2005h, 2\u2005h, 4\u2005h and 5\u2005h (P\u2009\u2264\u20090.039) and greater in AA-ORS compared to Z-ORS from 3 to 5\u2005h (P\u2009\u2264\u20090.030).There was a time x trial interaction effect . Net fluid balance was negative until 3\u2005h in all trials (P\u2009<\u20090.001), whereas at 4\u2005h it was not different from baseline in G-ORS and Z-ORS (P\u2009\u2265\u20090.230), but greater than baseline in AA-ORS (P\u2009=\u20090.004). At 5\u2005h, net fluid balance was not different from baseline in AA-ORS and G-ORS (P\u2009\u2265\u20090.999), but lower than baseline in Z-ORS (P\u2009<\u20090.001). Net fluid balance was greater in both AA-ORS and G-ORS compared to Z-ORS from 4 to 5\u2005h (P\u2009\u2264\u20090.015).For net fluid balance , with faster restoration in AA-ORS (P\u2009<\u20090.001) and G-ORS (P\u2009<\u20090.001) compared with Z-ORS. There was no difference in the calculated time for restoration between AA-ORS and G-ORS (P\u2009=\u20090.370). For the number of participants reaching full recovery of fluid balance , Cochran's Q test revealed a significant effect of beverage , or G-ORS . There was no difference between G-ORS and Z-ORS .The calculated time at which participants reached full recovery of net fluid balance  differed3.6.(P\u2009<\u20090.001) effects for sodium, potassium, and chloride balance (P\u2009<\u20090.001), which was not different between trials for sodium (P\u2009\u2265\u20090.579), potassium (P\u2009>\u20090.999) and chloride (P\u2009\u2265\u20090.290). Post-exercise, sodium balance ((P\u2009\u2264\u20090.001), except in AA-ORS at 2\u20133\u2005h (P\u2009\u2265\u20090.067) and in G-ORS at 4\u20135\u2005h (P\u2009\u2265\u20090.082), where it was not different from baseline, and at 4\u20135\u2005h in AA-ORS (P\u2009\u2264\u20090.004), where it was greater than baseline. Sodium balance was greater in AA-ORS compared to both G-ORS and Z-ORS, and in G-ORS compared to Z-ORS from 1 to 5\u2005h (P\u2009\u2264\u20090.031). Post-exercise, potassium balance ((P\u2009\u2264\u20090.017), except at 2\u20135\u2005h in AA-ORS (P\u2009\u2265\u20090.097) and 2\u20134\u2005h in G-ORS (P\u2009\u2265\u20090.071), where there were no differences compared to baseline. Potassium balance was greater in AA-ORS compared to Z-ORS from 1 to 5\u2005h (P\u2009\u2264\u20090.012). Post-exercise, chloride balance ((P\u2009\u2264\u20090.020), except at 3\u20135\u2005h in AA-ORS (P\u2009\u2265\u20090.305), where there were no differences from baseline. Chloride balance was greater in AA-ORS compared to both G-ORS and Z-ORS, and in G-ORS compared to Z-ORS from 1 to 5\u2005h (P\u2009\u2264\u20090.012).There were time x trial interaction  balance . The exe balance  was redu balance  was redu balance  was redu3.7.(P\u2009\u2264\u20090.019) for blood sodium, potassium, and chloride concentrations ((P\u2009\u2264\u20090.001) compared with baseline but had returned to baseline at 2 and 5\u2005h (P\u2009\u2265\u20090.232) in all trials ((P\u2009=\u20090.003). There were no differences between trials at any time point for blood potassium concentration (P\u2009\u2265\u20090.136), and compared with baseline, there were no differences in any post-exercise blood potassium concentrations (P\u2009\u2265\u20090.256), except an increase at 2\u2005h in AA-ORS  and remained elevated at 2 and 5\u2005h (P\u2009\u2264\u20090.007), with no differences to baseline at any time point in G-ORS or Z-ORS  and compared to G-ORS and Z-ORS at 5\u2005h (P\u2009\u2264\u20090.021).There were time x trial interaction effects trations . Post-exl trials . Blood s4.The present study demonstrates that following exercise-induced dehydration of \u223c2.6% body mass, all fluid balance markers , were enhanced with AA-ORS and G-ORS compared to Z-ORS, without any significant differences between AA-ORS and G-ORS. Furthermore, sodium and chloride balance were significantly greater in AA-ORS compared to both G-ORS and Z-ORS, as well as in G-ORS compared to Z-ORS from 1\u2005h post-exercise until the end of the study . Potassium balance was significantly greater in AA-ORS and G-ORS compared to Z-ORS from 1 to 5\u2005h post-exercise, with no difference between AA-ORS and G-ORS. These results are in line with our hypotheses, apart from that fluid balance measures were not different between AA-ORS and G-ORS. These findings suggest that an amino acid-based ORS is a viable alternative to a glucose-based ORS to support post-exercise rehydration, and in terms of sodium and chloride balance, provides superior recovery of electrolyte balance post-exercise.(P\u2009<\u20090.001) in AA-ORS (485\u2009\u00b1\u2009175\u2005ml) and G-ORS (542\u2009\u00b1\u2009213\u2005ml) compared to Z-ORS (779\u2009\u00b1\u2009223\u2005ml), with no difference between AA-ORS and G-ORS (P\u2009<\u20090.304). Ultimately, these effects on urine output meant that similar effects were apparent for fluid retention and net fluid balance over the rehydration phase. These fluid balance data are mainly consistent with the results of previous studies that have manipulated the sodium and/or chloride composition of post-exercise rehydration beverages  during the exercise-induced dehydration phase, and, consequently, the volume of drink consumed in the rehydration phase was also not different between trials. Therefore, differences between trials for post-exercise fluid balance variables were caused by differences in physiological responses to the ingested beverages. Total urine output over the 5\u2005h rehydration phase was reduced everages \u201313.In general, previous studies demonstrate that recovery of fluid balance after exercise-induced dehydration is directly related to the sodium content of the ingested beverage, but it seems that \u226540\u2005mmol/L sodium is generally required to observe significant differences compared to lower sodium concentration beverages \u201314. WhenP\u2009\u2264\u20090.05), with 19 (out of 20) returning to net fluid balance in AA-ORS compared with 11 and 14 in Z-ORS and G-ORS, respectively. This suggests that the AA-ORS beverage might provide a more consistent response across different participants. However, it is important to note that on average the difference between AA-ORS and G-ORS amounted to \u223c40\u2005ml at 4\u2005h and \u223c67\u2005ml at 5\u2005h and was not significantly different between trials (P\u2009>\u20090.999).Data comparing beverages with sodium concentration >50\u2005mmol/L are scarce in the literature and have observed inconsistent findings. Two studies have compared post-exercise beverages with sodium concentrations of \u223c100\u2005mmol/ and \u223c50\u2005mmol/L , 13, witThe findings for sodium and chloride balance are consistent with previous rehydration experiments that have manipulated sodium and/or chloride concentrations of rehydration beverages \u201314. ThesIt is interesting that sodium and chloride balance were greater after the AA-ORS beverage compared to the G-ORS beverage, but that these increases did not elicit alterations in urine output or other fluid balance measures. Similar findings have been reported previously . There aPotassium balance was greater throughout the rehydration phase in AA-ORS and G-ORS compared to Z-ORS, but the beverage concentrations of potassium were a lot closer than for sodium and chloride. Interestingly, and in contrast to sodium and chloride, the small increase in potassium concentration from that of Z-ORS beverage (\u223c12\u2005mmol/L) to AA-ORS and G-ORS beverages , did produce significant increases in potassium excretion in urine over the rehydration phase. The exercise-induced dehydration produced only small losses of potassium in sweat , consistent with previous studies , 43. In The finding that AA-ORS was comparable to G-ORS for fluid balance measures and superior for sodium and chloride balance may be of use to athletes looking to recover from dehydration without ingesting glucose or sugars. Whilst it is well established that glucose can facilitate water and sodium absorption across the small intestine through the cotransporter protein SLC5A1 , the incIn conclusion, the present study demonstrates that following exercise-induced dehydration, and when consumed in a volume equivalent to 125% of the exercise fluid loss, an amino acid-based ORS (AA-ORS) restores net fluid balance similarly compared with a glucose-based ORS (G-ORS), and superiorly, compared to a sugar-free ORS formulation (Z-ORS), potentially offering a solution to optimise post-exercise rehydration in numerous settings. Furthermore, AA-ORS produced significant increases in recovery of sodium and chloride balance compared to current glucose-based (G-ORS) and sugar-free (Z-ORS) commercial ORS. This may help facilitate longer-term recovery and/or provide the rationale for enhanced recovery in situations where electrolyte losses are proportionally greater . Future studies should seek to examine the efficacy of different ORS formulations in such situations."}
{"text": "Retraction Note: Sports Medicine (2022) 52:2627\u20132635 10.1007/s40279-022-01710-2The authors have retracted this article because, after publication, concerns were raised about the appropriateness of the studies included in the meta-analysis. Re-analysis by the authors found that seven of the 11 studies included in the meta-analysis did not fully meet the criteria for inclusion or exclusion. Both authors agree with this retraction."}
{"text": "ISME Communications 10.1038/s43705-022-00201-9, published online 16 December 2022Corrigendum to: Vulcanimicrobium alpinus (sic) gen. nov. sp. nov. along with higher-rank taxonomic names: the family , order , class (Eremiobacteriia), and phylum (Eremiobacterota). Vulcanimicrobium alpinum corrig. Yabe et al. 2023 was subsequently validated with a correction to the species name by Oren and G\u00f6ker [International Code of Nomenclature of Prokaryotes [Vulcanimicrobiaceae fam. nov., Vulcanimicrobiales ord. nov., Vulcanimicrobiia class. nov., and Vulcanimicrobiota phyl. nov. with following taxonomic descriptions.In the original version of the paper page 12-13), the authors described the bacterial name 2-13, theActinomycetota, which includes known photosynthetic lineages. However, the correct classification should have been Acidobacteriota.Furthermore, in the Introduction of the original paper , the authors inadvertently included The authors apologize for any confusion caused.Description ofVulcanimicrobiaceaefam. nov.Vulcanimicrobium, a bacterial genus; -aceae, ending to denote a family; N.L. fem. pl. n. Vulcanimicrobiaceae, the Vulcanimicrobium family)....(Vul.ca.ni.mi.cro.bi.o\u2019ta. N.L. neut. n. Candidatus Eremiobacteraeota\", \"Candidatus Eremiobacterota\" [Not validly published synonyms: \"cterota\" , 5\u20137.Vulcanimicrobium. Type genus is Vulcanimicrobium.The description is the same as for the genus"}
{"text": "As of 15 May 2023, the COVID-19 pandemic has resulted in a total of 765,903,278 cases and 6,927,378 cumulative deaths worldwide  . It is fJS, HL, FC, and SC designed and wrote the manuscript. All authors contributed to the article and approved the submitted version."}
{"text": "Page 1: The corresponding authors should be as given in this Erratum.Volume 11, no. 3, e05202-22, 2023,"}
{"text": "The following scientists assisted the journal by reviewing manuscripts during the period November 1, 2022 to October 31, 2023.We gratefully acknowledge their critical evaluation and valuable assistance in selecting articles for publication."}
{"text": "Mediators of Inflammation would like to express concern with the article titled \u201cI\u03baB Kinase Inhibitor VII Modulates Sepsis-Induced Excessive Inflammation and Cardiac Dysfunction in 5/6 Nephrectomized Mice\u201d [ed Mice\u201d  due to cThe authors apologized but did not provide a response to our request for further clarification and did not provide the original blots. As the journal has not received evidence that the findings are fundamentally flawed, it remains published, however, the conclusions should be viewed with caution."}
{"text": "Sci.: Atmos., 2023, 3, 399\u2013407, https://doi.org/10.1039/D2EA00133K.Correction for \u2018Ring-opening yields and auto-oxidation rates of the resulting peroxy radicals from OH-oxidation of \u03b1-pinene and \u03b2-pinene\u2019 by Ben H. Lee  The authors regret that a grant was missing in the acknowledgements section of the published article. The corrected acknowledgements section is shown below:Acknowledgementsx generation, and Henrik G. Kj\u00e6rgaard (University of Copenhagen) and Kristian H. M\u00f8ller (University of Copenhagen) for their suggestions on theoretical calculations.This work was funded by National Science Foundation Environmental Chemical Sciences (grant no. CHE-1807204 and CHE-2003359) and the European Research Council under the European Union's Horizon 2020 research and innovation programme under Grant No. 101002728. The authors acknowledge Ezra Wood (Drexel University) for his instructions on HOThe Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Also, for compounds 11\u201313 in In the original publication , there w"}
{"text": "In the original publication of the article, the Authors' Contributions statement were incorrectly published with X, Y, Z instead of the authors' names. This has been corrected with this erratum.Authors\u2019 contributions: All authors contributed to the manuscript conception and design. Material preparation, data collection were performed by Michelle Benstead, Elizabeth Clancy and Jess Heerde. The primary analysis was undertaken by Bosco Rowland and supported by Mohammadreza Mohebbi. The first draft of the manuscript was written by Bosco Rowland and all authors commented on previous versions of the manuscript. All authors read and approved the final manuscript. John Toumbourou and Jennifer Bailey were involved with securing the funds for data collection of the IYDS component of the study. Bosco Rowland, Robyn Horner and Paul Sharkey were involved with securing funding from the Melbourne Archdiocese of Catholic Schools (MACS).The original article has been corrected."}
{"text": "Open Biol.6, 150258 (Published online 1 March 2016). (https://dx.doi.org/10.1098/rsob.150258)f \u2018hBM-MSCs were transfected with either miR-NC or miR-150-3p inhibitor (anti-miR), and treated with either PBS (\u2212) or TNF-\u03b1 (+), followed by Western blot analysis to examined \u03b2-catenin protein levels\u2019 has overlap with fig.6b [e \u2018Levels of phosphorylated NF-\u03baB at Ser536 (p-NF-\u03baB) in hBM-MSCs treated with either PBS (as control) or TNF-\u03b1\u2019 overlap with fig. 2b [Following an investigation, we have found that the published manuscript has substantial overlap with published manuscripts ,2 in theThe authors have not been able to supply the raw data as requested, thus, the editors consider the conclusions of this article to be invalid. The authors have not responded to correspondence about this retraction.Jonathon Pines FRSOpen Biology.Editor-in-Chief,"}
{"text": "Author Contributions: Y.L. and H.L. performed the study and wrote the manuscript. L.C. contributed to data analysis. Z.C. and W.L. performed the technical modification and conceived the study.Yinghua Li was not included as an author in the original publication . With thFor authors Zihao Chen and Weizhong Li, the correct order as follows: Zihao Chen and Weizhong Li.liwz@smu.edu.cn.The authors want to add Weizhong Li as corresponding author, and change Weizhong Li\u2019s email address to 1\u00a0Department of Oral and Maxillofacial Surgery, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China2\u00a0Department of Urology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China3\u00a0School of Clinical Medicine, Baotou Medical College, Baotou 014040, ChinaIn the published publication, there were errors regarding the affiliations 1\u20133. The updated affiliations should be:The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "The journal retracts the paper entitled \u201cStrengthening public health surveillance through blockchain technology\u201d This retraction was approved by the Editor in Chief of the journal AIMS Public Health.The authors agreed to this retraction."}
{"text": "The Oncologist, Volume 26, Issue 10, October 2021, Pages e1862\u2013e1869, https://doi.org/10.1002/onco.13879This is a correction notice for: Anna Ozaki, Takaomi Kessoku, Yuki Kasai, Yuma Takeda, Naoki Okubo, Michihiro Iwaki, Takashi Kobayashi, Tsutomu Yoshihara, Yasushi Honda, Akiko Fuyuki, Takuma Higurashi, Hiroto Ishiki, Masataka Taguri, Shunsuke Oyamada, Noritoshi Kobayashi, Atsushi Nakajima, Yasushi Ichikawa, Elobixibat Effectively Relieves Chronic Constipation in Patients with Cancer Regardless of the Amount of Food Intake, In the originally published version of this article, the Disclosures section was incorrect and should have read as follows:This study was conducted without company funding; however, three co-authors have financial relationships to disclose. Takaomi Kessoku received lecture honoraria and research funding from EA Pharma Co. Ltd. and Mochida Pharmaceutical Co., Hiroto Ishiki received lecture honoraria from EA Pharma Co. Ltd., and Atsushi Nakajima received scholarship fee, lecture honoraria, and research funding from EA Pharma Co. Ltd. and Mochida Pharmaceutical Co.These details have been amended only in this correction notice to preserve the published version of record."}
{"text": "In the original publication , the funFunding: This work was sponsored by financial support from the Major Projects of Science and Technology of Anhui Province (202103a06020003), Anhui Province\u2019s key research and development program (202004b11020014), China National Key Research and Development Program (2019YFA0904300 and 2019YFA0904304), Key Research and Development Plan of Anhui Province (1804b06020342), Natural Science Foundation of Anhui Province (1908085MB48 and 1908085MB43), and National Natural Science Foundation of China (32070088).There was an error in the original publication. The wrong reagent information for antibody Bcl-2 was included. Corrections have been made to the 8th and 9th sentences of Section 2.8:PINK1, MFN1, MFN2, Nrf2, Bax, TFAM , Bcl-2  and \u03b2-actin .There was an error in the original publication. Due to carelessness, there was a word used incorrectly in the sentence. Corrections have been made to the 5th and 6th sentences of Section 3.7.The results showed that 6-OHDA slightly increased the expression of PINK1 and Parkin proteins, compared to that in the control group.In the original publication, there was a mistake in Figure 2 as published. Since the information of the previously used antibody Bcl-2 was wrong, we purchased a new Bcl-2 antibody and re-performed the relevant experiments, to make replacements for Figure 2D. The corrected version of Figure 2 appears below. The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "Retraction Note: Stem Cell Research & Therapy (2020) 11:2https://doi.org/10.1186/s13287-019-1492-6The Editors-in-Chief have retracted this article after concerns were raised about potential image re-use between Fig.\u00a04D and 5D and the potential partial overlap between Fig.\u00a06A and Supplementary Fig.\u00a04A. The authors were unable to provide raw data for Figs.\u00a04 and 5. The raw images provided for Fig.\u00a06A and Supplementary Fig.\u00a04A contained further partial image overlaps between different experimental conditions. The authors were also unable to share evidence of ethics approval. Therefore, the Editors have lost confidence in the data presented here.Yuanlin Song agrees to this retraction. Yun Feng and Xiaotong Yang do not agree to this retraction. Linlin Wang, Xiaoying Ma, Ocholi Don, Xiaoyan Chen and Jieming Qu have not responded to any correspondence from the editor/publisher about this retraction."}
{"text": "Retraction Note: Cell & Bioscience (2020) 10:410.1186/s13578-019-0371-2The Editor-in-Chief has retracted this article after the investigation by the publisher found that potential image overlap in Figs.\u00a02f, 4e, 5f, 6e and 7a. The authors failed to provide raw images and an ethical approval document.In addition, the corresponding author stated that he was not aware of the publication of this article and his email address provided on submission was not his email address. None of the authors responded to any correspondence from the editor/publisher about this retraction."}
{"text": "Nature Communications 10.1038/s41467-021-23242-5 published online 20 May 2021Retraction to: The authors have retracted this article. In this article, we reported that chicken embryo fibroblasts (CEFs) could be transdifferentiated to primordial germ cells (PGCs) and used to generate viable offspring after transplantation to chicken embryos. After publication, it was brought to our attention  that some of the analyses to support our conclusions regarding the origin of offspring were insufficient. Specifically, self-crossing, microsatellite and feather color data were thought to be inconclusive evidence that the offspring were donor derived. No concerns were raised regarding data integrity. However, additional review by two external experts concurred with the concerns raised, and we acknowledge that alterations to the experimental design would have allowed the origin of offspring to be determined with less ambiguity. The authors are performing further experiments and intend to submit a new manuscript for peer review in due course. All authors agree to this retraction."}
{"text": "In the original publication , there wThe authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "Molecular and Cellular Biochemistry (2020) 476:1-1010.1007/s11010-020-03814-7The authors have retracted this article because, after publication, it was brought to their attention that some images overlap with those in other articles. In particular:Figure\u00a07B (panel 400X vs. Ad-shNC) overlaps with Fig.\u00a07D (panel Ki67 vs. Ad-shNC) of Figure\u00a07B (panel 100X vs. Ad-snNC) overlap with Fig.\u00a02F MCF-7 (panel 100X vs. NC) of [The authors have stated that the immunohistochemistry experiments were performed by a third party; this was not reported in the article. All authors agree to this retraction."}
{"text": "This corrects the article \u201cSocial media for research discourse, dissemination, and collaboration in rheumatology\u201d in volume 3 on page 172.In the December 2022 issue of Rheumatology and Immunology Research, the paper titled \u201cSocial media for research discourse, dissemination, and collaboration in rheumatology\u201d :169-179. doi: 10.2478/rir-2022-0031), was published with some errors:The sentence \u201cAmong 26 rheumatology journal families, 21 (81%) have active Twitter accounts.\u201d should be changed to \u201cAmong 28 rheumatology journal families, 24 (86%) have Twitter accounts.\u201d The sentence, \u201cHowever, only 5 (19%) have a designated social media editor,\u201d should be changed to \u201cHowever, only 10 (36%) have a designated social media editor.\u201dIn The errors do not change the scientific conclusions of the article. The authors would like to apologize for the errors and any inconvenience caused."}
{"text": "Figures 4A and 7A. The authors failed to provide a satisfactory explanation and the complete raw data during the investigation, which was conducted in accordance with Frontiers' policies. As a result, the data and conclusions of the article have been deemed unreliable and the article has been retracted.Following publication, concerns were raised regarding the integrity of the images in the published figures. Image duplication concerns were identified within This retraction was approved by the Chief Editor of Frontiers in Cellular Neuroscience and the Chief Executive Editor of Frontiers. The authors did not state whether they agree or disagree with this retraction."}
{"text": "Dutcher bodies varied in size, number, and location in the nucleus  translocation is a poor prognostic factor for both overall survival and progression\u2010free survival; therefore, the t translocation needs to be considered when Dutcher bodies are detected in myeloma patients.Dutcher bodies are closely associated with the translocation t, causing the Masahiro Manabe, Nobuhiro Sogabe, Satoru Nannno, and Ki\u2010Ryang Koh designed the study. Masahiro Manabe, Yuuji Hagiwara, and Reiko Asada analyzed the data. Masahiro Manabe and Ki\u2010Ryang Koh collected the clinical data and specimens. Masahiro Manabe, Yuuji Hagiwara, and Reiko Asada wrote the manuscript. All of the authors have reviewed and approved the final manuscript.The authors have no competing interests to declare.There are no funding sources to declare.The patient provided her consent for the publication of this case report."}
{"text": "The authors wish to make the following corrections to their paper . Eight s"}
{"text": "The authors regret that the published version of this article contained errors in the methods section of the abstract and in In the methods section of the abstract, the non-inferiority margin was written as 5%. This was a typographical error. We have provided the correct version, which is 1.5%, as stated in the main body of the paper and the supplementary appendix. The sentence now reads: \u201cThe study team determined that the safety of the combined MDA would be non-inferior to that of separate MDAs if the upper limit of the two-sided CI for the difference in rates was equal to or lower than 1.5%\u201d.In These corrections do not change the interpretation or conclusions of the paper. The authors would like to apologise for any inconvenience caused."}
{"text": "The Moffitt Cancer Center investigated this article  and deteFig 1a, AKT panelFig 2a, IB: \u03b1-HA IgG panelFig 3b, MST2 panelFig 4c, MST2 panel and Cleaved-MST2 panelFollowing their findings of misconduct the Moffitt Cancer Centre recommended retraction of .The PLOS Editors also noted that the Fig 1a and Fig 1c MST2 Cleaved-MST2 panels appear to partially overlap when one of the panels is flipped horizontally. PLOS did not follow up on this additional concern.The authors did not respond to editorial communications regarding the above concerns and did not provide any underlying data.PLOS ONE Editors retract this article.In light of the outcome of the institutional investigation and the concerns affecting multiple figure panels that question the integrity of these data, the DK and ZY agreed with the retraction. SS, MDC, SK, and JQC either did not respond directly or could not be reached. ZY stands by the article\u2019s findings."}
{"text": "The authors regret that the Acknowledgments section was omitted from the original article. Acknowledgments are as shown below.M.-F. L. was supported by the Hierarchical Green-Energy Materials (Hi-GEM) Research Center, from the Featured Areas Research Center Program within the framework of the Higher Education Sprout Project by the Ministry of Education (MOE) and the Ministry of Science and Technology (MOST 111-2112-M-006-020) in Taiwan.T.-R. C. was supported by the 2030 Cross-Generation Young Scholars Program from the National Science and Technology Council (NSTC) in Taiwan (Program No. MOST111-2628-M-006-003-MY3), National Cheng Kung University (NCKU), Taiwan, and National Center for Theoretical Sciences, Taiwan. This research was supported, in part, by the Higher Education Sprout Project, Ministry of Education to the Headquarters of University Advancement at NCKU.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Ann Transl Med 8: 1157, 2020].Following the publication of this paper, it was drawn to the Editor's attention by a concerned reader that certain of the Transwell cell invasion assay data shown in Fig. 2E on p. 8 were strikingly similar to data that had appeared in different form in a different article by different authors at different research institutes that had already been accepted for publication [Yan C, Gao L, Qiu X and Deng C: Schisandrin B synergizes docetaxel-induced restriction of growth and invasion of cervical cancer cells Oncology Letters, the Editor has decided that this paper should be retracted from the Journal. The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a satisfactory reply. The Editor apologizes to the readership for any inconvenience caused.Owing to the fact that some of the data in the above article were already under consideration for publication prior to its submission to"}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office never received a reply. The Editor apologizes to the readership for any inconvenience caused.Owing to the fact that the contentious data in the above article had already been published elsewhere prior to its submission to"}
{"text": "In the original publication , there wThe authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "In the original publication , there wTable 1. Demographic and postoperative outcomes of the patients included in the study. Age and ligations per procedure are expressed as a mean with the range between parentheses. Follow-up is expressed as a median.In the original publication , there wThe authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "Correction to: Pediatric Cardiology (2022) 44:312\u2013324 10.1007/s00246-022-03074-wIn the original publication of the article, only family names were mentioned.The authors\u2019 full names are:Raphael Joye, Maurice Beghetti, Julie Wacker, Iliona Malaspinas, Maya Bouhabib, Angelo Polito, Alice Bordessoule & Dipen C. Shah.This has been corrected in this paper."}
{"text": "The authors regret that there was an error in the labelling of the axes shown in the graphs in Figs. 1b and 1c. In both cases, the x-axis label should read E9.5 KO / E9.5 WT (Log2) and not E9.5 WT / E9.5 KO WT (Log2) as originally stated.i.m.dykes@ljmu.ac.uk.The email address for the corresponding author has been changed to The authors would like to apologise for any inconvenience caused."}
{"text": "Bursaphelenchus zvyagintsevi sp. n. The corrected main text appears below in Section 2.1:In the original publication , there wBursaphelenchus zvyagintsevi sp. n.Adults : http://zoobank.org/urn:lsid:zoobank.org:act:71BDE14D-B778-40FE-977D-D910F701DE6D (accessed on 13 August 2023). Body curved ventrally. Stylet base slightly expanded, but without distinct knobs. Cephalic annuli faintly distinct through light microscopy. Median bulb ellipsoid, large; valve median to sub-median of bulb. Excretory pore located at nerve ring or at posterior end of the median bulb. Lateral field with two incisures.The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a satisfactory reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of the above paper, it was drawn to the Editors' attention by a concerned reader that certain of the western blotting data shown in Fig. 5 were strikingly similar to data appearing in different form in other articles by different authors, some of which have been retracted. Owing to the fact that the contentious data in the above article were already under consideration for publication, or had already been published, elsewhere when it was submitted to"}
{"text": "All the authors agree to the publication of this corrigendum, and also apologize to the readership for any inconvenience caused.The authors were able to re-examine their original data files, and realized that these figures had been inadvertently assembled incorrectly . The revised versions of"}
{"text": "Smartphone interventions effect in pediatric subjects on the day of surgery: a meta-analysis Li L, Ma J, Ma D and Zhou X. (2021) Front. Surg. 8:759958. doi: 10.3389/fsurg.2021.759958A Retraction of the Systematic Review Article The journal and Chief Editors retract the 16 December 2021 article cited above.Following publication, concerns were raised regarding abnormal similarities with the contents of other articles published by unrelated research groups. A subsequent investigation, which was conducted in accordance with Frontiers' policies, raised strong concerns over the authorship of the articles, resulting in a loss of confidence in the findings presented in the article.The authors have not responded to this retraction.This retraction was approved by the Chief Editors of Frontiers in Surgery and the Chief Executive Editor of Frontiers."}
{"text": "The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated.In the original publication , there w"}
{"text": "Retraction Note: J Exp Clin Cancer Res40, 92 (2021)10.1186/s13046-021-01889-8The Editor in Chief has retracted this article. After publication, concerns were raised about the following issues:\u2022 OSRC2-ZNF582-AS1 CON panel in Fig.\u00a04c appears to partially overlap with the OSRC2-MT-RNR1 OE panel in Fig.\u00a09g;\u2022 The highlighted sequences in Fig.\u00a06g do not appear to correspond to the positions of the peaks as reported in Fig.\u00a06a;\u2022 There appears to be substantial overlap between this paper and two previously-published papers  and 2]  2] that \u2022 The reference number of the ethics permit as reported in the article appears to have been used in multiple other studies dealing with topics and studies that appear to require separate approvals.The authors provided an explanation which did not address the concerns adequately. The Editor in Chief, therefore, has lost confidence in the integrity of the article\u2019s findings. The corresponding author has stated on behalf of all authors that they disagree to this retraction."}
{"text": "In checking the blots and records from that time, the authors found that the loading controls for both experiments had been imaged at the same time and on the same film, leading to the inadvertent selection of the wrong image for Fig. 2 A.The corrected The error appears in print and in PDFs downloaded on or before September 8, 2023. The authors apologize for the error and any confusion."}
{"text": "Cell Death & Disease 10.1038/s41419-020-2250-5, published online 22 January 2020Retraction to: Two images in Fig. 4h appear highly similar to those in Fig. 1f of [The images in Fig. 7b appear highly similar to those in Fig. 8a of  with difThe images in Fig. 8a appear highly similar to those in Figs. 4j and 5h of .The Editors-in-Chief have retracted this article. After publication, concerns were raised regarding image similarities between this article and previous papers from different author groups, specifically:Fig. 4d SKBR-3-TR CQ+ GAPDH appears highly similar to Fig. 5d SKBR-3-TR Control GAPDH.Fig. 4d BT474-TR CQ- and CQ+ GAPDH appear highly similar to Fig. 5d BT474-TR Control and miR-567 GAPDH, respectively.Some of the blots in Figs. 7d and 8c appear to have irregularities in the backgrounds.The GSE104076 microarray dataset information [Further checks by the Publisher identified a number of further concerns:The Editors-in-Chief therefore no longer have confidence in the presented data and the conclusions of the article.None of the authors have responded to any correspondence from the editor or publisher about this retraction."}
{"text": "In the article by Kwiatkowska et\u00a0al.The first sentence of the 9th paragraph of the Discussion section should read \u2018The figures indicate a current lifetime risk of approximately one in six for NMSC in females and one in four for males.\u2019The authors apologize for this error."}
{"text": "SLCO4A1\u2010AS1 promotes cell growth and induces resistance in lung adenocarcinoma by modulating miR\u20104701\u20105p/NFE2L1 axis to activate WNT pathway. Cancer Med. 2020;9:7205\u20107217. wileyonlinelibrary.com), has been retracted by agreement between the authors, the journal Editor\u2010in\u2010Chief, Dr Stephen Tait and John Wiley and Sons Ltd. The retraction has been requested by the Authors as the study design provided for insufficient results to support the argument, invalidating the conclusions of the paper.The above article, published online in Cancer Medicine on 6th August 2020 in Wiley Online Library ( SLCO4A1\u2010AS1 promotes cell growth and induces resistance in lung adenocarcinoma by modulating miR\u20104701\u20105p/NFE2L1 axis to activate WNT pathway. Cancer Med. 2020;9:7205\u20107217. wileyonlinelibrary.com), has been retracted by agreement between the authors, the journal Editor\u2010in\u2010Chief, Dr Stephen Tait and John Wiley and Sons Ltd. The retraction has been requested by the Authors as the study design provided for insufficient results to support the argument, invalidating the conclusions of the paper.The above article, published online in Cancer Medicine on 6th August 2020 in Wiley Online Library ("}
{"text": "In the original publication, there was a mistake in Figure 3 as published . We obseThe authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "The authors would like to make the following corrections to this paper .In the original article, there was a mistake in Table 2. In the legend of Table 2, the indicators of a negative influence correspond to the number 1 and the indicators of a positive influence correspond to the number 2. The correct version of The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "Retraction Note: Journal of Cardiothoracic Surgery (2020) 15:309https://doi.org/10.1186/s13019-020-01355-0The Editor-in-Chief has retracted this article due to the lack of adherence to the journal's ethical standards and editorial policy. After publication, concerns were raised regarding the trial registration and ethics approval of this study. The authors have provided the ethics approval, which was dated after the patient recruitment start date.All authors agree to this retraction."}
{"text": "Sci., 2020, 11, 1926\u20131934, https://doi.org/10.1039/C9SC05506A.Correction for \u2018A H The corrected version is displayed below. The data analysis and conclusions in the paper remain unchanged.It has come to the authors\u2019 attention that there was one error in Fig. S6 in the ESI. An incorrect image for the H&E stained liver for the Fe-GA/CaOFig. S6 H&E staining of organs from each group of mice after different treatment. Scale bar: 100 \u03bcm.\u00a0The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Retraction Note: J Ovarian Res 12, 118 (2019)https://doi.org/10.1186/s13048-019-0593-2The Editors-in-Chief have retracted this article. After publication, concerns were raised regarding highly similar images between this article and a number of other articles that were submitted and published within a close time frame \u20135.The authors have stated that the image duplication occurred due to the use of a shared platform, and that the original data could not be retrieved. Due to the number and severity of the duplications, the Editors-in-Chief no longer have confidence in the presented data.All authors agree to this retraction."}
{"text": "Sci., 2016, 7, 4117\u20134124, https://doi.org/10.1039/C6SC00268D.Correction for \u2018Structural tuning of organoruthenium compounds allows oxidative switch to control ER stress pathways and bypass multidrug resistance\u2019 by Mun Juinn Chow  Fig. 3 was included in the original article, where two incorrect images were used, namely RAS-1H LD treatment and RAS-1H HD treatment, resulting in an unintentional duplication. The correct version of Fig. 3 is presented here, which is now consistent with Fig. S5a from the ESI of the original publication.The authors regret that an incorrect version of Fig. 3 Complexes RAS-1H and RAS-1T induce early time-point ROS and activate cellular antioxidant defense mechanism. (a) Detection of ROS with carboxy-H2DCFDA (20 \u03bcM) after treatment with RAS-1H and RAS-1T for 3 h, 6 h and 9 h using a microplate assay. Mean \u00b1 s.e.m. . (b) Detection of ROS with a fluorescence microscope after treatment for 6 h. (c) Western blot analysis of Nrf-2, a central protein in cellular antioxidant defence and (d) expression levels of Nrf-2 target gene in AGS cells after treatment with RAS-1H, RAS-1T and cisplatin at LD and HD for 6 h and 24 h. Homogeneous protein loading determined with reference to actin and gene expression normalized against tbp levels.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editor's attention by a concerned reader that certain of the cell migration and invasion assay data shown in Fig. 5C were strikingly similar to data appearing in different form in other articles by different authors at different research institutes. Owing to the fact that the contentious data in the above article were already under consideration for publication, or had already been published, prior to its submission to"}
{"text": "Scientific Reports 10.1038/s41598-018-26496-0, published online 25 May 2018Retraction of: 2.In Figure\u00a02A images of scratch wound assays in BxPC-3 and Panc-1 cells in control and I-BET762 groups appear to overlap with data described in6.In Figure\u00a02D images of colony formation assays in BxPC-3 and Panc-1 cells in control and I-BET762 groups appear to overlap with data described in7.In Figure\u00a03A the images of sphere formation assays appear to overlap with those described inThe Editors have retracted this Article. After the publication of this Article it was brought to the Editors' attention that some of the data appear to overlap with data in other articles with different authors, where they are attributed to different experiments. Specifically:The Editors reached out to the Authors to request raw data. The Authors were unable to provide the data and the concerns remain unresolved. The Editors therefore no longer have confidence in the results presented in this Article. All Authors agree to this retraction."}
{"text": "The authors regret that the original version of above paper, unfortunately, contained three typos consisting of the incorrect spelling of \u201cToll-like receptor\u201d acronym, TRL4 instead of TLR4. The correct spelling is shown below:Title: \u201cInflammatory extracellular vesicles prompt heart dysfunction via TLR4-dependent NF-\u03baB activation\u201dIntroduction: \u201cThe systemic release of different subsets of cytokines and proteins by polarized M1/M2 macrophages implies the activation of toll-like receptor (TLR) and subsequent NF-\u03baB signalling cascades [8].\u201dMethods: \u201ctransmission electron microscopy; TLR: activation of toll-like receptor\u201dThe correction made in this erratum does not concern any published data. The authors apologize for any inconvenience that the errors may have caused."}
{"text": "Correction: Aging Clinical and Experimental Research (2020) 32:2141\u20132158 10.1007/s40520-020-01677-yIn the Acknowledgements section of this article the grant number relating to National Institutes of Health given was incorrectly given asThe authors would like to thank Benjamin D Keane for his assistance in preparing the manuscript. The authors would also like to acknowledge generous support from the Carinato Charitable Foundation, Mark and Ingeborg Holliday, Kristin Hudson and Rob Goldman, and Ms. Susan Brice and Mr. Jordi Esteve.and should have beenThe authors would like to thank Benjamin D Keane for his assistance in preparing the manuscript. The authors would also like to acknowledge generous support from the Carinato Charitable Foundation, Mark and Ingeborg Holliday, Kristin Hudson and Rob Goldman, and Ms. Susan Brice and Mr. Jordi Esteve. In addition, the authors would also like to acknowledge funding from the National Institutes of Health (NIH), through grant #R01CA225002.The original article has been corrected."}
{"text": "Scientific Reports 10.1038/s41598-023-43475-2, published online 26 September 2023Retraction of: The Authors have retracted this Article. After the publication of the Article, the Authors discovered that their TAW-2000 rock testing machine had developed a malfunction. The machine was used in most of the experiments and the Authors cannot be certain at which point the machine failed. The Authors therefore no longer have confidence in the data.All Authors agree to this retraction."}
{"text": "Wang JY, Lu L and He X analyzed the data. Ma LJ provided critical inputs on interpretation of the study. All authors had access to the data. All authors read and approved the final manuscript as submitted."}
{"text": "Silene succulenta promote in vitro MCF-7 breast carcinoma cell apoptosis by cell cycle arrest and in silico mitotic Mps1/TTK inhibition\u2019 by Sarah A. Badawy et al., RSC Adv., 2023, 13, 18627\u201318638, https://doi.org/10.1039/D3RA01793A.Correction for \u2018New cyclic glycolipids from  The authors regret that the name of one of the authors  was shown incorrectly in the original article.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "In the original publication , there wThe authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "Computer tomography showed opacification of the right sinonasal air spaces Written informed consent was obtained from the patient for the publication of this case report and the accompanying images, and the case report was approved by the Ethical Committees of the First Affiliated Hospital of Xi'an Jiaotong University.The authors have confirmed clinical trial registration is not needed for this submission.The authors have confirmed patient consent statement is not needed for this submission."}
{"text": "There are errors in the Funding section. The correct Funding statement is: The authors acknowledge the financial support by the University of Graz."}
{"text": "The Science of Nature grants the Arnold Berliner Award to the lead author of an article which represents excellent, original, and\u2014especially\u2014interdisciplinary research. As such, the winning articles clearly reflect the vision of Arnold Berliner (Autrum As every year, r Autrum . Springer Autrum , a 2-yeaI am very proud that, this year, the Editorial Board of our journal has decided to award Cynthia Tedore Fig.  for the On behalf of the Editorial Board, I congratulate Cynthia Tedore, the two co-first authors Mateusz Glenszyk and David Outomuro, and the rest of the team on the award."}
{"text": "Nature Communications 10.1038/ncomms8872, published online 05 August 2015Retraction to: 1 where a different material was used. Figures 4b and 4c contain sections with an unexplained blank section not matching the background or image. The EDX images in Figures 4d\u20134f were modified before publication. The background noise in the XRD spectra in Supplementary Figure 9 shows a much higher degree of overlap than would be expected for different cycles.The authors have retracted this article because there are a number of flaws in the figures and data. Figure 2c and the EDS mappings in Figures 2d, 2e and 2f were re-used from the authors previous workThe authors sincerely apologize to the scientific community for any confusion caused by these errors. All authors agree to this retraction."}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editor's attention by a concerned reader that the western blotting data shown in Fig. 4A were strikingly similar to data appearing in different form in other articles by different authors at different research institutes, several of which have been retracted. Owing to the fact that the contentious data in the above article were already under consideration for publication prior to its submission to"}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive any reply. The Editor apologizes to the readership for any inconvenience caused.Owing to the fact that some of the data in the above article had already been published, or were under consideration for publication, prior to its submission to"}
{"text": "In the above\u2010stated article, the authors mistakenly placed a duplicated images of Collagen I staining for the UIRI and UIRI/AMD groups in Figure\u00a0The authors would like to apologize for any inconvenience caused."}
{"text": "Cell Death and Disease 10.1038/s41419-020-03266-3, published online 12 December 2020Retraction to: The Editors-in-Chief have retracted this article at the authors\u2019 request. After publication, concerns were raised regarding image similarities between this article and a number of previously published articles, specifically:Several images in Fig. 6D and E appear highly similar to those in Fig. 6C and D in , Fig. 6DFig. 5E input appears highly similar to Fig. 4E input in .The authors have stated that the images in Fig. 6 were misused and could not be reproduced, which undermined the reliability of the conclusions. The Editors-in-Chief therefore no longer have confidence in the presented data and the conclusions of the article.All authors agree to this retraction."}
{"text": "The authors made the following changes to their paper . The autFigure 6I (marked in red) was corrected fromtoA correction has been made to Section 3.7:The sentence \u201cIn contrast, HSD17B4 remained unchanged and the AR, ER1 and SF-1 were conversely down-regulated for NCI-H295R.For TVBF-7, again, all levels remained unchanged\u201d was modified to \u201cIn contrast, HSD17B4 remained unchanged, SF-1 was upregulated and AR and ER1 were conversely down-regulated for NCI-H295R. For TVBF-7, again, all levels remained unchanged\u201d.A correction has been made to Section 4, paragraphs 4 and 5:The sentence \u201cOf note, SF-1 is a key regulator of human sex determination [39] and was upon FSK stimulation strikingly different regulated in NCI-H295R (down), MUC-1 (up) and TVBF-7 (unchanged)\u201d was corrected to \u201cOf note, SF-1 is a key regulator of human sex determination [39] and its activation might lead to different downstream effects in tissues of male and female origin\u201d.The sentence \u201cOf note, the AR was again markedly different regulated following the same patterns as observed for SF-1 in NCI-H295R (down), MUC-1 (up) and TVBF-7 (unchanged)\u201d was corrected to \u201cOf note, the AR was markedly differently regulated in NCI-H295R (down), MUC-1 (up) and TVBF-7 (unchanged)\u201d.The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "The authors would like to make the following corrections to the publication :Marcellina M. Stolting was not included as an author in the original publication [Author Contributions: Conceptualization, D.v.L. and M.M.S.; Methodology, D.v.L. and M.M.S.; Data curation, J.C.M.V.; Validation, J.C.M.V.; Formal analysis, D.v.L. and J.C.M.V.; Investigation, D.v.L.; Project administration, D.v.L.; Resources, D.v.L.; Writing\u2014original draft, D.v.L. and M.M.S.; Visualization, D.v.L., J.C.M.V. and R.J.C.; Writing\u2014review & editing D.v.L., J.C.M.V. and R.J.C.; Supervision, R.J.C. All authors have read and agreed to the published version of the manuscript.lication . The corMarcellina M. Stolting\u2019s affiliation and email is added (affiliation 3): Cat Behaviour Consultancy, P.O. Box 11375, 1001 GJ Amsterdam, The Netherlands; info@kattengedragstherapie.nl.Accordingly, The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. The original publication has also been updated."}
{"text": "In the original publication  there waE. coli and S. aureus, respectively.Due to this correction in Figure 6, the reported values of the released AgNPs in the original publication  from hydThe authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "Food Sci Nutr. 2021; 9: 2531\u20132540 (https://doi.org/10.1002/fsn3.2202).Tian, L, Lin, X, Xiong, Y, Ding, Z. \u201cDesign and performance test on segmented\u2010differential threshing and separating unit for head\u2010feed combine harvester.\u201d wileyonlinelibrary.com), has been retracted by agreement between the authors, the journal Editor in Chief, Y. Martin Lo, and Wiley Periodicals LLC. The retraction has been agreed as the author has discovered an incorrect coded value in the levels of test factors in Table\u00a02, thus affecting the interpretation of the results so that the conclusions of this manuscript are not reliable.The above article, published online on March 8, 2021 in Wiley Online Library ( Food Sci Nutr. 2021; 9: 2531\u20132540 (https://doi.org/10.1002/fsn3.2202).Tian, L, Lin, X, Xiong, Y, Ding, Z. \u201cDesign and performance test on segmented\u2010differential threshing and separating unit for head\u2010feed combine harvester.\u201d wileyonlinelibrary.com), has been retracted by agreement between the authors, the journal Editor in Chief, Y. Martin Lo, and Wiley Periodicals LLC. The retraction has been agreed as the author has discovered an incorrect coded value in the levels of test factors in Table\u00a02, thus affecting the interpretation of the results so that the conclusions of this manuscript are not reliable.The above article, published online on March 8, 2021 in Wiley Online Library ("}
{"text": "Cell Death Dis 10: 717, 2019. The authors regret that the data in question featured in the original"}
{"text": "Retraction note: Nanoscale Res Lett (2021) 16:28https://doi.org/10.1186/s11671-021-03477-3The Editors in Chief have retracted this article. After publication, concerns were raised about the appearance of Western blots and the data in Table 1 that indicates that miR-124-3p may have been the target of the assays instead of miR-124-5p. The authors were unable to provide uncropped gels and blots and stated that some blots have been modified for \"aesthetics \" reasons. The Editors, therefore, have lost confidence in the integrity of the article's findings. Jian Hu agrees with this retraction. Chunling Tang did not respond to correspondence from the Editor about this retraction."}
{"text": "Furthermore, they apologize to the readership for any inconvenience caused.The authors have re-examined their data and realized that"}
{"text": "The journal retracts the 28 June 2017 article cited above.Following publication, concerns were raised regarding the integrity of the images in the published figures, with areas of image duplication in Figures 2E and 6G. The authors failed to provide a satisfactory explanation during the investigation, which was conducted in accordance with Frontiers' policies. As a result, the data and conclusions of the article have been deemed unreliable and the article has been retracted.This retraction was approved by the Chief Editors of Frontiers in Molecular Neuroscience and the Chief Executive Editor of Frontiers. The authors did not agree to this retraction."}
{"text": "This is a peer-review report submitted for the paper \u201cAre We Sure We Fully Understand What an Infodemic Is? A Global Perspective on Infodemiological Problems.\u201dThis paper  is a wel"}
{"text": "The authors would like to correct a mistake in The corrected The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. The original publication has also been updated."}
{"text": "Nature 10.1038/s41586-022-04966-w Published online 22 June 2022Correction to: In the version of the article initially published, in the penultimate paragraph of the \u201cAttribution and administrative data\u201d section, the sentences now reading \u201cNotably, after including controls, the gender gap remains for all job titles except undergraduates. The gender gap similarly remains for 9 out of 13 fields for publications and 8 out of 13 fields for patents, after including controls\u201d have been corrected from \u201cNotably, after including controls, the gender gap is significant for all job titles except undergraduates. The gender gap is similarly significant for 9 out of 13 fields for publications and 5 out of 13 fields for patents, after including controls\u201d. In the \u201cEthical approval\u201d section, under \u201cAnalytical sample\u201d, \u201cweighted\u201d was added to the sentence now reading \u201cIf these numbers are converted to rates, the weighted attribution rate on scientific documents was 3.17%\u201d. These changes have been made to the HTML and PDF versions of the article."}
{"text": "The correct version of the result in the abstract can be found below:In the original published version of this article, the authors provided the results of the abstract incorrectly and the result of the abstract alone has been updated. \"The number of rib fractures was associated with an increased risk of pulmonary injuries: pulmonary contusion ; hemothorax ; pneumothorax ; and hemopneumothorax .\"Original:\"The number of rib fractures was associated with an increased risk of pulmonary injury: all pulmonary injuries, OR 1.85, 95% CI 1.59\u20132.16, p\u00a0<\u00a00.01; pulmonary contusion, OR 1.50, 95% CI 1.33\u20131.69, p\u00a0<\u00a00.01; hemothorax, OR 1.49, 95% CI 1.32\u20131.68, p\u00a0<\u00a00.01, and pneumothorax, OR 1.47, 95% CI 1.30\u20131.65, p\u00a0<\u00a00.01.\"Requested Change:The authors apologize for the errors. Both the HTML and PDF versions of the article have been updated to correct the errors.The authors declare the following conflict of interests: Fukushima, Kambe, Aramaki, and Oshima received research funding for this study from the SUBARU Corporation; however, the SUBARU Corporation had no role in study design, data collection and interpretation, or the decision to submit the work for publication. Ichikawa, Isshiki, Nakajima, and Sawada have no conflicts of interest to declare related to the study."}
{"text": "Following the publication of this article , concernThe following panels appear similar:Lanes 1\u20133 of the Fig 2D p-PERK panel and lanes 2\u20134 of the Fig 2D IRE1\u03b1 panel.The Fig 2D p-PERK panel of this study  and laneThe IRE1\u03b1 panel of this study .Lanes 2\u20135 of the Fig 4A GRP78 panel of this study  and the Lanes 3\u20136 of the Fig 4A p-STAT3 panel of this study  and the The Fig 6D p-JAK2 panel of this study  and the The S2 Fig A p-STAT3 panel of this study  and laneLanes 2\u20133 of the S2 Fig A STAT3 panel of this study  and laneThe authors did not respond to editorial requests for underlying data.PLOS ONE Editors retract this article.In light of the concerns affecting multiple figure panels that question the integrity of these data, the CW agreed with the retraction. XY, HL, XZ, LZ, XL, and SS either did not respond directly or could not be reached."}
{"text": "The corrected figure is shown here. The error appears in print and in PDFs downloaded before April 10, 2023. The authors apologize for the error and any confusion.After publication, it was discovered that the image in"}
{"text": "Retraction Note: Diabetologia (2022) 65:1519-153310.1007/s00125-022-05718-1The authors have retracted this article following the discovery of a data processing error that impacts the results. Specifically, the number of cells sequenced and analyzed was significantly lower than reported in the article. The authors have reanalyzed the data and concluded that, while the overall conclusions have not changed, many of the details have. The nature of this error makes correction unfeasible.The authors thank colleagues for bringing this error to their attention and apologize to the community.All authors agree with this retraction."}
{"text": "Figure\u00a03. Many of the references cited are also considered to be inappropriate or outdated. An investigation was conducted in accordance with Frontiers\u2019 and the Committee on Publication Ethics (COPE) guidelines, whereby it was confirmed that the complaints were valid.Following publication, concerns were raised to the journal regarding factual inaccuracies throughout the Review article text and errors in the data presented in This retraction was approved by the Chief Editors of Frontiers in Plant Science and the Chief Executive Editor of Frontiers. The authors agree to the retraction."}
{"text": "Because of a production error,the affiliations of two authors were transposed. Here are the correctaffiliations for Bart de Nijs and Stuart Gibson:Bartde Nijsbd355@cam.ac.ukNanoPhotonics Centre, Cavendish Laboratory, Universityof Cambridge,Cambridge CB3 0HE, U.K. Email: Stuart Gibsons.j.gibson@kent.ac.ukSchool of Physics and Astronomy,University of Kent, CanterburyCT2 7NH, U.K. Email:"}
{"text": "Retraction Note: BMC Complement Med Ther 19, 318 (2019)10.1186/s12906-019-2718-yThe Editor has retracted this article because the DAPI, TUNEL and Merged images in Fig.\u00a06 do not appear to correspond with each other. In addition, the authors have not been able to provide original western blotting data that match the images shown in this article. The Editor therefore no longer has confidence in the results and conclusions presented. Zi-ming Zhao and Yuan-liang Liu disagree with this retraction. Wei Liu, Hua-feng Pan and Li-zhu Lin have not responded to correspondence from the Editor about this retraction."}
{"text": "Molecular Genetics & Genomic Medicine. 2019, 7(12), e991. https://doi.org/10.1002/mgg3.991.Ying, X., Zhu, J., and Zhang, Y. \u201cCircular RNA circ\u2010TSPAN4 promotes lung adenocarcinoma metastasis by upregulating ZEB1 via sponging miR\u2010665\u201d. https://onlinelibrary.wiley.com), has been retracted by agreement between the authors, the journal Editor\u2010in\u2010Chief Dr. Suzanne Hart, and John Wiley & Sons. The retraction has been agreed due to concerns raised by the authors regarding problems with the statistics and also concerns raised by a third party about image manipulation in Figure 2. The journal team have investigated and determined that these concerns undermine the reliability of the data presented and the article\u2018s conclusions.The above article, published online on 01 October 2019 in Wiley Online Library ("}
{"text": "This article has been retracted: Several images in this paper are duplicates of images in other published papers. In Figure 5C, a panel is duplicated within Figure 6D of another paper [er paper . In Figuer paper . In Figuer paper . Althoug65823-65835. https://doi.org/10.18632/oncotarget.19502Original article: Oncotarget. 2017; 8:65823\u201365835."}
{"text": "Correlation analysis between required surgical indexes and complications in patients with coronary heart disease by Tao M, Yao X, Sun S, Qin Y, Li D, Wu J, Xiong Y, Teng Z, Zeng Y and Luo Z (2022) Front. Surg. 9:948666. doi: 10.3389/fsurg.2022.948666A Retraction of the Original Research Article Following publication, the publisher uncovered evidence that several false identities were used in the peer-review process. The assignment of false reviewers was confirmed by an investigation conducted in accordance with Frontiers' policies and the Committee on Publication Ethics (COPE) guidelines.The investigation also uncovered concerns about the presentation and validity of the data in the article. The authors did not respond to contact regarding the data presented in the article.This retraction was approved by the Chief Editors of Frontiers in Surgery and the Chief Executive Editor of Frontiers.The authors did not respond to contact regarding this retraction."}
{"text": "After this article  was publIn Fig 5A, the two H&E stain Sham panels are duplicated in the cortex Sham panels in Fig 4A in .In Fig 5B, the two Masson stain Sham panels are duplicated in the cortex Sham panels in Fig 4B in .In Fig 5C, the two H&E stain Sham panels are duplicated in the medulla Sham panels in Fig 4A in .In Fig 5D, the two Masson stain Sham panels are duplicated in the medulla Sham panels in Fig 4B in .The \u03b2-actin 42kDa panel in Fig 6A appears similar to the \u03b2-actin 42kDa panel in Fig 8A.In Fig 6C, the two Sham panels are duplicated in the Sham panels in Fig 7C when rotated 180\u00b0, the cortex Sham panels in Fig 5B in , and theIn Fig 6D, the two Sham panels are duplicated in the medulla Sham panels in Fig 5B in .In Fig 6D, the two CKD panels are duplicated in the CKD panels in Fig 7D.In Fig 7D, the two Sham panels are duplicated in the medulla Sham panels in Fig 6B in .In Fig 8E, the two Sham panels appear similar to the Sham panels in Fig 7B in .In Fig 8F, the two Sham panels appear similar to the Sham panels in Fig 7C in .During editorial follow-up on these issues, the corresponding author stated that the eight Sham panels in Figs 5A-D, the four Sham panels in Figs 6C-D, the two CKD panels in Fig 6D, and the four Sham panels in Figs 7C-D in  were incPLOS ONE Editors retract this article.In light of the extent of the above issues with Figs 5\u20138 that question the reliability of these data, the CTC agreed with the retraction. YHC, CAY, CCY, and SPH either did not respond directly or could not be reached.Owing to the concerns about similarities with previously published content , publish"}
{"text": "Retraction Note : Journal of Eating Disorders (2023) 11:79 10.1186/s40337-023-00808-wThe authors have retracted this article following discussions with multiple stakeholders. The authors offer their deepest apologies for the distress and the unintended negative impact of this piece."}
{"text": "Correction to: Journal of Hematology & Oncology (2019) 12:20 https://doi.org/10.1186/s13045-019-0708-7Further duplicated images have been found in Fig S6D with different data labels;In Fig. S6H an image of mice appears to not interact with the background in Fig. S6H.The Editor in Chief has retracted this article. After publication, concerns were raised in relation to overlaps between Figs. 2G and 4G as well as 2G and 4E. Additional investigation by the publisher found further concerns:Therefore, the Editor in Chief has lost confidence in the integrity of the results. Bin Xiong has stated on behalf of all authors that they disagree to this retraction."}
{"text": "The published article  has beenPolymers Editorial Office and the authors, the paper has been retracted and will be marked accordingly. https://www.mdpi.com/2073-4360/13/19/3354.Following its publication, the authors contacted the Editorial Office regarding legal issues related to confidentiality and a copyright issue. Zhengzhou University was not aware that the article had been submitted for publication and did not agree to the publication of the paper in its current form. Thus, in agreement with the This retraction has been approved by the Editor-in-Chief of the journal.The authors agree to this retraction."}
{"text": "They also apologize to the readership for any inconvenience caused.Following the publication of the above article, an interested reader drew to the authors\u2019 attention that, for the morphological observations of chondrocytes portrayed in"}
{"text": "The authors wish to correct the following errors in the original paper .dE and iPAR, were scaled by a factor of 100. Therefore, the reported coefficients and corrections were all a factor of 100 higher for the reported units. This erroneous scaling factor was applied to all wavebands and iPAR in both data used to compute the sensor-specific, temperature-dependent dark corrections (Equation (1) in the manuscript) and in the profile data to which the corrections were applied (by Equation (5) in the manuscript). We make the following corrections.The authors realized a typo in the software used for analysis in the original manuscript by which the input data, for both The following correction has been made to the Abstract:The corrections are based on modeling the temperature of the radiometer and show an average bias in the measured value of nearly Profile Extraction, Quality Control and Modeling under Section 2: Materials and Methods, in the sixth paragraph, we make the correction:In the subsection PAR| < 0.5 We constrained measurements to the range |Profile Extraction, Quality Control and Modeling under Section 2: Materials and Methods, in the seventh paragraph, we make the correction:In the subsection dEd/dTs is small (\u22122 nm\u22121 \u00b0C\u22121) and hence not detectable relative to other environmental processes if the temperature gradient in a profile is too small.This test is important as In Section 3: Results, in the second paragraph, we make the correction:In Section 4: Discussion and Summary, in the first paragraph, we make the following correction:For this BGC-Argo dataset, the mean absolute temperature corrections on In Section 4: Discussion and Summary, in the fourth paragraph, we make the following correction:They provide a model that includes drift correction, where in certain, but rare, cases they observed a drift as much as In Section 4: Discussion and Summary, in the fourth paragraph, we make the following correction:The values of our modeled coefficients In Section 4: Discussion and Summary, in the fourth paragraph, we make the following correction:dE: at 10 m, our average PAR correction is on the order of 0.001% of the 10 m measured PAR value, analogous to the average 10 m correction at all three wavelengths. Overall we find very similar results between our method and . For We update We update We apologize for the inconvenience or confusion caused by our error in the original manuscript. The changes do not affect the method presented, but they do affect the magnitude of the bias identified in the sensors. The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "Editorial Expression of Concern: Journal of Cardiovascular Magnetic Resonance (2017) 19:1 10.1186/s12968-016-0318-2The Editor-in-Chief would like to alert readers that concerns have been raised regarding the data in this article.Journal of Cardiovascular Magnetic Resonance\u00a0in December 2020\u00a0to report that authors Ferreira, Piechnik and Wijesurendra had re-analyzed the available data and were unable to reproduce some of the results reported in this article.Authors Vanessa M. Ferreira, Stefan K. Piechnik and Stefan Neubauer reached out to the\u00a0Thorough\u00a0 reanalysis of available data\u00a0found that the strong links between the splenic signal intensity change and delta spleen T1, and the ability of delta spleen T1 to predict the splenic switch-off sign, could not be independently reproduced, although the general\u00a0observations\u00a0reported in Table 2\u00a0(that the spleen T1 decreases significantly in response to Adenosine)\u00a0and inter-observer reproducibility\u00a0of delta spleen T1\u00a0could be reproduced.As a result of the information available, the Editor-in-Chief advises readers to interpret the results of this publication with due caution.Authors Rohan S. Wijesurendra, Rina Ariga, Eylem Levelt, Stefan Neubauer, Stefan K. Piechnik and Vanessa M. Ferreira agree to this Expression of Concern. Authors Alexander Liu, Masliza Mahmod, Andreas Greiser, Mario Petrou, George Krasopoulos, John C. Forfar, Rajesh K. Kharbanda and Keith M. Channon have not responded to correspondence from the editor regarding this Expression of Concern."}
{"text": "Retraction Note : Journal of Eating Disorders (2023) 11:79 10.1186/s40337-023-00808-wThe authors have retracted this article following discussions with multiple stakeholders. The authors offer their deepest apologies for the distress and the unintended negative impact of this piece."}
{"text": "Horiz., 2023, 10, 171\u2013178, https://doi.org/10.1039/D2MH01117D.Correction for \u2018Elucidating the role of multivalency, shape, size and functional group density on antibacterial activity of diversified supramolecular nanostructures enabled by templated assembly\u2019 by Amrita Sikder  The authors wish to rectify an error in the published article: in The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "In the original publication , there wThe authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "In the original publication , there wThe authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "Yu JX and Yuan DD carried out data curation. Li L and Wang YJ provided critical inputs on design, analysis, and interpretation of the study. All the authors had access to the data. All authors read and approved the final manuscript as submitted."}
{"text": "The Royal Society of Chemistry is publishing this expression of concern in order to alert readers that concerns have been raised regarding the integrity of the NMR data in the ESI.Several impurity peaks have been removed from the NMR spectra. The authors have provided the original raw data, however, an independent expert has stated it would not be appropriate to re-publish the original spectra and requested the authors reproduce their results.An expression of concern will continue to be associated with the article until we receive conclusive evidence regarding the reliability of the reported data.Laura Fisher30th June 2023RSC AdvancesExecutive Editor,"}
{"text": "Namely, the stereochemistry of twopyridyl rings of 2-phenylpyridine (ppy) and 4,6-difluorophenylpyridineligands (two Ir\u2013N coordination bonds) in 2 and 3 were drawn in cis positions around Ir cationin our original publication, and it is corrected to trans positions in this correction. This change does not impact the object,results, and conclusions in the original publication.Page 11326: The chemical structuresof \u0394-"}
{"text": "Chem. Chem. Phys., 2023, 25, 462\u2013470, https://doi.org/10.1039/D2CP03841B.Correction for \u2018Helium nanodroplets as an efficient tool to investigate hydrogen attachment to alkali cations\u2019 by Siegfried Kollotzek  In the published version of this manuscript, acknowledgement for one of the funding sources was inadvertently omitted. The authors would like to include \u201cS. K. is supported by the Austrian Science Fund (FWF) W1259-N27\u201d in the Acknowledgements.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "This is a peer review submitted for the paper \u201cA Framework for a Statistical Characterization of Epidemic Cycles: COVID-19 Case Study.\u201dThis paper  attempts2 values, which readers can be expected to understand (and those who do not could learn via appropriate citations). Certainly, the formula for R2 is not necessary to include. These types of revisions would make the paper a more readable length.I think the paper would benefit from focusing on the central point, with only a minor description of any methods necessary to make that point. For example, most of section 2 (\u201cOn the Nature of the Observed Data\u201d) includes a lengthy description of the use of moving averages and RThe authors claim the Chinese epidemic cycle has a Gaussian shape, but even in their own drawing it appears much more like a gamma distribution (as would be expected) than Gaussian. They may want to reconsider this section.The crux of this paper seems to be looking for epidemic curves that appear similarly shaped in various countries, and using that to predict the curves for countries where the cycle has not yet reached what the authors term the \u201cMLCE end.\u201d I have never heard of epidemic predictions using a method such as this, and it seems there are many far superior methods for estimating trajectory, so this is a curious choice.Citations require appropriate formatting for journal publications."}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Owing to the fact that the contentious data in the above article had already been published prior to its submission to"}
{"text": "Retraction note: Nanoscale Research Letters (2021) 16:165https://doi.org/10.1186/s11671-021-03608-wThe Editors in Chief have retracted this article. After publication, concerns were raised concerning the authors' contributions and the integrity of the article. The authors did not respond to requests for further clarification and did not supply raw data or the ethics permit. The Editors, therefore, have lost confidence in the integrity of the article's findings. The authors did not respond to any correspondence from the Editor about this retraction."}
{"text": "This article written by Smithsonian Ocean staff provides a good overview of hydrothermal vent communities suitable for non\u2010scientific readers.This report reviews the microbial diversity and microbe\u2010mineral interactions in deep\u2010ocean hydrothermal environments.Ridgeia piscesae.This report dealt with the rich taxonomic diversity in vent communities, with a particular focus on those within the tubeworm This article covered microbial succession during a change from active to inactive deep\u2010sea sulfide chimneys.This paper is a broad overview of microbial population at deep\u2010sea areas containing hydrothermal vents.This page provides a summary of a published paper on gene transfer in deep\u2010sea hydrothermal vent bacteria. It contains a link to the original article.This article by Jannasch and Mottl is one of the classics in the field of hydrothermal vent chemistry and microbiology.There are numerous videos on life in deep\u2010sea environments. This is one of the longest and most comprehensive of those.This page of the Microbe Wiki describes deep sea vent properties, global locations, bacterial communities, and eukaryotic organisms present in those environments.This report describes the isolation and characterization of a green sulfur bacterial species from a deep\u2010ocean hydrothermal vent that is proposed to use geothermal radiation as a source of photons to be absorbed by its photosynthetic pigments.This article reviews knowledge of, and techniques for studying, hydrogen uptake and hydrogen evolving enzymes involved in hydrogen cycling at hydrothermal vents.This study samples several deep\u2010sea hydrothermal vents to sequence viruses that were present. The general conclusions were that diverse viruses were present with different assemblages that are highly localized to specific areas and hosts."}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editor's attention by a concerned reader that a data panel portraying cell migration and invasion assay data shown in Fig. 7C was strikingly similar to a panel that had appeared in another article by different authors at a different research institute, which had been submitted for publication earlier than the submission date of this article. Moreover, a large number of overlapping data panels were identified comparing the data in Figs. 4A and B and 7C and D. Owing to the fact that the contentious data in Fig. 7C in the above article were already under consideration for publication prior to its submission to"}
{"text": "This is a peer-review report submitted for the paper \"COVID-19 and Cybersecurity: Finally, an Opportunity to Disrupt?\"Conclusion section in order to make it more clearly informative.Dear Authors, the article  is well"}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Owing to the fact that the contentious data in the above article had already been published prior to its submission to"}
{"text": "The values 0.82 and 0.88 should be 0.10 and 0.80, respectively. The error has now been corrected online, and the authors regret any confusion that it has caused."}
{"text": "In \u201cAcceptability and Feasibility of a Return-to-Work Intervention for Posttreatment Breast Cancer Survivors: Protocol for a Co-design and Development Study\u201d :e37009) the authors noted an error.The following sentence and reference  were delParticipants will be instructed to not work on existing or unappreciated resources for people affected by cancer, such as a pamphlet or a website that already exists in Canada .All subsequent references have been renumbered accordingly.The correction will appear in the online version of the paper on the JMIR Publications website on July 18, 2023, together with the publication of this correction notice. Because this was made after submission to PubMed, PubMed Central, and other full-text repositories, the corrected article has also been resubmitted to those repositories."}
{"text": "Lastly, the authors apologize to the readership for any inconvenience these errors may have caused.After having examined their original data, the authors have realized that these figures were inadvertently assembled incorrectly. The corrected versions of"}
{"text": "Aging Cell, 20(3), e13332. https://doi.org/10.1111/acel.13332Hyun\u2010ju Lee, Seong Gak Jeon, Jieun Kim, Ri Jin Kang, Seong\u2010Min Kim, Kyung\u2010Min Han, HyunHee Park, Ki\u2010taek Kim, You Me Sung, Hye Yeon Nam, Young Ho Koh, Minseok Song, Kyoungho Suk, Hyang\u2010Sook Hoe. In the published version of Lee et al.\u00a0, the autThe authors would like to apologize for the inconvenience caused."}
{"text": "After verifying the source data, the unit has been replaced by ng/mL in both the text and the figure. This has been corrected online.The authors apologize for this error and any confusion it may have caused."}
{"text": "Following publication, concerns were raised regarding the integrity of the images in the published figures. The authors failed to provide a satisfactory explanation during the investigation, which was conducted in accordance with Frontiers\u2019 policies.As a result, the data and conclusions of the article have been deemed unreliable and the article has been retracted.The co-authors, Dr. Weiliang Jiang and Dr. Jie Shen agreed to this retraction.This retraction was approved by the Chief Editor of Frontiers in Cellular and Developmental Biology and the Editor-in-Chief of Frontiers."}
{"text": "Scientific Reportshttps://doi.org/10.1038/srep28666, published online 27 June 2016Retraction of: The Editors have retracted this Article.1, which reports an experiment in a different cell type. The Editors reached out to the Authors to request raw data, but were not able to contact any of them, nor to obtain any up to date contact information. Given the concerns about the veracity of the data, the Editors no longer have confidence in the results and conclusions presented in this Article.After the publication of this Article it was brought to the Editors\u2019 attention that some of the western blot data in Figure\u00a03(b) appear to replicate western blot data in Figure\u00a01B inKun Liu, Ming-Ming Gu, Xin-Ming Chen, Shuang-Long Zhang, Kang-Jun Yu, and Qing-Sheng You have not responded to correspondence from the Editors about this retraction. The Editors were not able to obtain current email addresses for Hong-Lin Chen and Shuo Wang."}
{"text": "Furthermore, they regret any inconvenience caused to the readership.After re-examining their data, the authors have realized that the control blots in"}
{"text": "Oncogenesis 10.1038/s41389-020-0230-3, published online 12 May 2020Retraction to: The Editor-in-Chief has retracted this article. Concerns were raising regarding Figure 2H. This figure appears to overlap with Figure 3G in an article by different authors that was simultaneously under consideration in another journal .The authors have provided partial raw data to address this concern. However, they have stated that some of the original data are no longer available. The Editor-in-Chief therefore no longer has confidence in the presented data.All authors agree to this retraction."}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive any reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of the above paper, it was drawn to the Editors\u2019 attention by a concerned reader that cell migration and invasion assay data shown in Fig. 5C were strikingly similar to data appearing in different form in other articles by different authors, which have been retracted. Owing to the fact that the contentious data in the above article were already under consideration for publication, or had already been published, elsewhere when it was submitted to"}
{"text": "Scientific Reports 10.1038/srep26051, published online 17 May 2016Retraction of: Editors have retracted this Article.After publication of this paper concerns about ethical oversight of this study were brought to the attention of the Editors. The Authors were not able to provide documentation of appropriate approval from an ethics committee in either Niger or Senegal, where the participants in this study were based.Catherine Robert agrees with this retraction. Matthieu Million, Jean-Christophe Lagier, Souleymane Brah, Cheikh Sokhna, Philippe Parola, and Didier Raoult disagree with this retraction. Caroline Michelle and Bernard Henrissat did not explicitly state whether they agree with this retraction. Maryam Tidjani Alou, Saber Khelaifia, Dipankar Bachar, Niokhor Dione, Perrine Hugon, Vincent Lombard, Fabrice Armougom, Julien Fromonot, Alexandre Fabre, and R\u00e9gis Guieu did not respond to correspondence from the Editors about this retraction. The Editors were not able to confirm current contact details for Aldiouma Diallo."}
{"text": "The authors wish to make the following correction to this paper :Section 2.1. Study Design and Participants\u201d, there was a mistake in the initial date of patient recruitment, which should be 4 June 2021, instead of 1 June 2021. The corrected date appears below:In the original publication, in \u201c\u201cWe conducted a single-center, observational prospective cohort study involving MHD patients between 4 June and 31 December 2021 at Maharaj Nakorn Chiang Mai Hospital, which is an affiliated hospital of Chiang Mai University, Thailand.\u201dThe authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "Sci., 2023, 14, 8458\u20138465, https://doi.org/10.1039/D3SC03090C.Correction for \u2018A visible-light-driven molecular motor based on barbituric acid\u2019 by Kim Kuntze  The authors regret that the link included in the data availability statement was incorrect in the original article. The corrected data availability statement is shown below:https://figshare.com/articles/dataset/A_Visible-Light-Driven_Molecular_Motor_Based_on_Barbituric_Acid/23276999.The datasets supporting this article have been uploaded as part of the ESI. All cartesian coordinates for all the compounds considered are provided as a separate additional file in a fig-share repository with the following DOI: The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Following the original publication of Masunaga et al.\u00a0, the aut20\u2009=\u2009\u221266.1 .Hence, the sentence should read as follows: The purified pleostene exhibited an optical rotation value of [\u03b1]DThe authors apologize for this error and any confusion it may have caused."}
{"text": "Correction to: Quality of Life Research (2023) 32:2403\u20132413 10.1007/s11136-023-03402-4The authors regret that the affiliation of Professor Maria Grazia Benedetti published in the article was not correct. Hence, the updated affiliation of the author is provided in this correction.The authors would like to apologise for any inconvenience caused."}
{"text": "Error in Conflicts of InterestConflicts of Interest was described inaccurately. Please replace it with the following paragraph under the heading of Conflicts of Interest:In the original publication , Conflic\u201cThe publication presents the results of an industry collaborative research project. The project involves students and staff from Griffith University , Central Queensland University  and Bioproton Pty Ltd. . C.T. is supported by a PhD scholarship from Bioproton Pty Ltd.\u201d The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "Following the publication of this article , concernThe Fig 5C Bcl-2 and \u03b2-actin panels appear similar when color levels are adjusted to visualize the background.The Fig 6B 5\u00b5M (right) panel appears similar to the Fig 6B 10\u00b5M (left) panel.The Fig 8A AMP-001 GAPDH and AMP-002 GAPDH panels appear similar.\u25cb There appears to be a region in lanes 1 and 2 in the \u03b2-actin results presented in the underlying data for the Fig 5C panels which does not appear to match the remainder of the blot, suggestive of inappropriate image manipulation.\u25cb The underlying data provided in S1 File for Fig 5C do not appear to match the corresponding panels presented in Fig 5C.\u25cb In the underlying data provided for Fig 5C, the sizes for the Bax and the \u03b2-actin results are both marked as 20kDa, despite their different locations on the blot.\u25cb There appears to be a region in lanes 1\u20134 in the total PARP results presented in the underlying data for the Fig 8B panels which does not appear to match lane 5, suggestive of inappropriate image manipulation.\u25cb The underlying data provided in S1 File for Figs 8A and 8B does not appear to match the corresponding panels presented in Fig 8.There are concerns with the underlying blot data presented in the published S1 File:\u25cb The first TMD231 + 5 uM AMP-001 image  and the third TMD231 + 5 uM AMP-001 image .\u25cb The first TMD231 + 10 uM AMP-001 image  and the third TMD231 + 10 uM AMP-001 image .The following S4 Fig panels appear to partially overlap:The corresponding author did not provide a clarification for the above concerns involving Figs 5, 8, and S1 File.The last author clarified that the panel duplication in Fig 6 was the result of an inadvertent image duplication introduced during the preparation of this figure, and the authors provided a replacement figure. The last author also clarified that the partially overlapping panels in S4 Fig represent triplicate data obtained from the same plates of cells, and apologized for the inadvertent errors in the published Fig 6.PLOS ONE Editors retract this article.In light of the concerns affecting multiple figure panels and underlying data that question the integrity of the data presented in Figs 5 and 8, and the S1 File, the CM agreed with the retraction. RSP and MT did not agree with the retraction. HN responded but neither agreed nor disagreed with the retraction decision. STV, RP, SR, and MA either did not respond directly or could not be reached."}
{"text": "Following the publication of this article , concernIn Fig 2d, band 2 in the PFMA-3 p-P53 panel appears similar to band 1 in the XRT p-P53 panel. Additionally, band 1 in the XRT panel appears to be flanked by vertical discontinuities.In Fig 2d, band 6 in the PFMA-3 p-P53 panel appears to be flanked by horizontal and vertical discontinuities.\u25cb The 24 hour PFMA-3 panel in Fig 3a and the 24 hour XRT panel in Fig 3b.\u25cb The ctrl PFMA-3 panel in Fig 3a and the 48 hour PFMA-3 panel in Fig 3b.\u25cb The 48 hour PFMA-3 panel in Fig 3a and the 3 hour XRT panel in Fig 3cIn Fig 3 the following panels appear similar when levels are adjusted to visualise the background:In Fig 3d, bands 1\u20134 in the XRT p-P53 panel appear similar.In Figure 4d, bands 2 and 5 in the XRT Cleaved Caspase-9 panel appear similar.In Fig 9a, when levels are adjusted to visualise the background in the ctrl BODIPY panel there is a vertical discontinuity on the left side of the panel.The authors stated that underlying data for Figs 2, 3, and 4 were no longer available. The authors concurred with the assessment that band 2 and band 1 in the respective Fig 2d panels appeared similar. The PLOS Editors remain concerned about this figure. The authors stated the concerns in Fig 3a, 3b, and 3c were likely due to errors made during figure preparation. The authors stated that whilst similarities could be observed between bands denoted above in Fig 3d and Fig 4d, they asserted that these bands were not the same images. The authors stated the cause of the vertical discontinuity in Fig 9a was potentially caused by an error in the editing software used to process the image and provided the original underlying image to resolve the concern.PLOS ONE Editors retract this article.In light of the concerns affecting multiple figure panels that question the reliability of these data, the FB agreed with the retraction and apologized for the issues in the article. GCastellani, MS, LI, IZ, AMM, AC and EO did not agree with the retraction. SR, AT, DM and GCucchi either did not respond directly or could not be reached."}
{"text": "The authors wish to add two authors to the original paper .The authors are requesting a change of authorship for this paper: The paper was published with just Marko M\u00e4kynen and Fernando S. Schlindwein as authors when it should have listed all four authors .The relevant manuscript contributors are not fully listed. After confirming all authors\u2019 detailed contributions. It was decided to correct the authorship to appropriately list the significant contributions to the intellectual content of the manuscript.The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. This correction was approved by the academic editor. The original publication has also been updated."}
{"text": "This is a peer-review report submitted for the paper \u201cEarly Experience With Neutralizing Monoclonal Antibody Therapy for COVID-19: Retrospective Cohort Survival Analysis and Descriptive Study.\u201dIn this paper , the autAlthough this topic is not entirely new, the paper looks good to me and confirms other previously published data.As Tables 1 and 2 are quite complex, they need a clear legend and not just the title, as reported.For greater clarity, the figures should also be better explained.In the Introduction and Discussion when talking about COVID-19, for the sake of clarity, we need to better explain the inflammation that kills people and not just go straight to the monoclonal antibodies. Therefore, to make this paper more interesting for the readers of this important journal, the authors should expand the discussion on this subject a little to give a wider view to the reader."}
{"text": "The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an Expression of Concern to notify readers.It has been noted by a reader that there is a similarity of the Western blots with those in several other unrelated publications suspected of originating from a third party. The reader has also identified highly similar data between this publication, and that of Mao et al. 2017 (doi: 10.3892/ijo.2017.4122) and Lv et al. 2019 (doi: 10.2147/cmar.s199818).The authors were contacted regarding the concerns raised and provided the Editorial Office with copies of the original Western blots, however minor differences in the shape and spacing of the bands, as well as the addition/removal of background and surface features can be seen between the original submitted Figures and the raw Western blots images provided post-publication. The authors state that these differences are due to staining due to improper preservation."}
{"text": "Retraction Note: BMC Complement Med Ther 17, 240 (2017).10.1186/s12906-017-1642-2The Editor has retracted this article. After publication, concerns were raised about three of the figures:Panels A1 and F1 in Fig.\u00a08 appear to be duplicates.Panels D and F in Fig.\u00a06 appear to overlap.Panel E2 in Fig.\u00a02 appears to be identical with Fig.\u00a03 in .The authors have provided data files. However, these have not allayed the concerns and the Editor therefore no longer has confidence in the results and conclusions presented. None of the authors has responded to correspondence from the Editor about this retraction."}
{"text": "Bioinformatics, Volume 39, Issue 7, July 2023, https://doi.org/10.1093/bioinformatics/btad412.This is a correction to \u201cRetraction of: DeepCRISTL: deep transfer learning to predict CRISPR/Cas9 functional and endogenous on-target editing efficiency\u201d, The retraction notice text has been updated, because we have subsequently discovered that the authors did not receive the journal\u2019s communications to them asking them to address the flaws. This correction does not change the outcome or decision to retract."}
{"text": "In the original publication , ref. ,  corresponding microscopic model diagrams before and after growing VACNTs, respectively. Reprinted with permission from Elsevier 2023 [36].The citation has now been inserted in the caption of Figure 3 and should read: SEM images of CF: (a) adsorption and desorption curves; (b) the pore width. Reprinted with permission from Elsevier 2023 [36].The citation has now been inserted in the caption of Figure 4 and should read: BET analysis results [36] of CF with growing VACNTs in situ: (The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "Sci., 2021, 12, 2898\u20132908, https://doi.org/10.1039/D0SC05172A.Correction for \u20182-Mercaptomethyl-thiazolidines use conserved aromatic\u2013S interactions to achieve broad-range inhibition of metallo-\u03b2-lactamases\u2019 by Maria-Agustina Rossi  The ESI of the original article has been updated to include the corrected CIF file of compound L-1a.The authors regret that the CIF file of compound L-The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "This is a peer-review report submitted for the paper \u201cPostacute Sequelae of COVID-19 and Adverse Psychiatric Outcomes: Protocol for an Etiology and Risk Systematic Review.\u201dThe authors lay out a reasonable protocol for this type of investigation .Do you have any serious concerns about the manuscript such as fraud, plagiarism, unethical or unsafe practices?No.Have authors\u2019 provided the necessary ethics approval (from authors\u2019 institution or an ethics committee)?Yes.How would you rate the English language quality?High quality.Is the reasons for conducting the study and its objectives clearly explained?Yes.Is the study design appropriate?Yes.Are sufficient details provided so that the method can be replicated?Yes.Are datasets available so that others could use them?Not applicable.Based on your answers in section 3 how could the author improve the protocol?It is appropriate as it is.Do you have any other feedback or comments for the Author?The authors lay out a reasonable protocol for this type of investigation that is based on a fairly standard approach with the standard GRADE grading approach.Verified manuscript: The content is scientifically sound, and only minor amendments (if any) are suggested."}
{"text": "In the original publication , there wThe authors state that the scientific conclusions are unaffected. This correction wasapproved by the Academic Editor. The original publication has also been updated."}
{"text": "Following the publication of this article , concernIn Fig 1A there appears to be an overlap between the 20ng/mL CD40L and 40ng/mL CD40L panels. Additionally, there are several cells in the 40ng/mL CD40L panel that do not appear in the 20ng/mL CD40L panel despite the overall overlap.The actin panel in Fig 2B appears similar to the actin panel in Fig 6A despite representing different experimental conditions.PLOS ONE Editors remain concerned about the issues in Figs 1, 2, and 6 which cannot be resolved in the absence of the original underlying data.The authors did not respond to the concerns raised and the underlying data was not provided for editorial review. The PLOS ONE Editors retract this article.In light of the concerns affecting multiple figure panels that question the integrity and reliability of these data, the All authors either did not respond directly or could not be reached."}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors\u2019 attention by a concerned reader that certain of the scratch-wound data shown in Fig. 3A were strikingly similar to data appearing in different form in another article by different authors. Owing to the fact that the contentious data in the above article had already been published elsewhere prior to its submission to"}
{"text": "After having conducted an independent investigation of this paper in the Editorial Office, it was discovered that certain data in Fig. 2 were shared with the following paper, which had already been published by different authors at a different research institute, and which itself has subsequently been retracted: Huang X, Zhou W, Zhang Y and Liu Y: High expression of PTGR1 promotes NSCLC cell growth via positive regulation of cyclin-dependent protein kinase complex. Biomed Res Int: 5230642, 2016.Oncology Letters has determined that this paper should be retracted from the journal. The Editor apologizes to the readership for any inconvenience caused.On account of the fact that certain data in this paper had already been published in another article, and in line with the authors\u2019 request, the Editor of"}
{"text": "BJGP Open 2022; DOI: https://doi.org/10.3399/BJGPO.2022.0126, there was an omission from the competing interests paragraph. The text should read: \u2018Nicholas Panay is the founder of a private menopause clinic and has received funds for research and speaking from pharmaceutical companies. He was not involved in the analysis of this study. The other authors have no competing interests.\u2019 The online version has been corrected.In the article by Alsugeir"}
{"text": "The above article, published online on 03 January 2020 in Wiley Online Library (https://onlinelibrary.wiley.com), has been retracted by agreement between the authors, the journal's Editor\u2010in\u2010Chief, Professor Rong Fu, and Wiley Periodicals, LLC. The retraction has been agreed following concerns raised by a third party about image duplication . Upon investigation, the journal determined that the duplicated images were provided by a third party company who performed the experiments on behalf of the authors. The authors were unable to verify the provenance of the images. As a result, the journal no longer has confidence in the results and conclusions drawn and are issuing a retraction. The above article, published online on 03 January 2020 in Wiley Online Library (https://onlinelibrary.wiley.com), has been retracted by agreement between the authors, the journal's Editor\u2010in\u2010Chief, Professor Rong Fu, and Wiley Periodicals, LLC. The retraction has been agreed following concerns raised by a third party about image duplication . Upon investigation, the journal determined that the duplicated images were provided by a third party company who performed the experiments on behalf of the authors. The authors were unable to verify the provenance of the images. As a result, the journal no longer has confidence in the results and conclusions drawn and are issuing a retraction."}
{"text": "Cell Death Discovery 10.1038/s41420-022-01000-w, published online 20 April 2022Retraction to: The Editor in Chief has retracted this article. Concerns were raised about the apparent overlap between the two middle panels in Fig. 5H (si-RNF-44-1) and insufficient information about size of tumours in Fig. 7a. The authors did not provide raw data or proof that an ethics approval had been obtained before the beginning of the study. Additionally, Shaohua Ge stated they were not aware of the contents of the article, nor the submission process, because the email address provided on submission was not their email address. The authors did not state explicitly whether they agree to this retraction."}
{"text": "Figures 1A, 2C, 6B. The authors failed to provide a satisfactory explanation during the investigation, which was conducted in accordance with Frontiers\u2019 policies. Given the concerns about the validity of the data, and the lack of raw data, the editors no longer have confidence in the findings presented in the article.Following publication, concerns were raised regarding the integrity of the images in the published figures. Image duplication concerns were identified in This retraction was approved by the Chief Editors of Frontiers in Pharmacology and the Chief Executive Editor of Frontiers. The authors agree to this retraction."}
{"text": "In the original publication , there wThe authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "The authors wish to point out an inadvertent error in"}
{"text": "Title.There was a spelling mistake in the original publication . A corre\u201cApplicability of International Autoimmune Hepatitis Group (IAIHG) Scoring System for Autoimmune Hepatitis in Pediatrics\u201dSimple Summary.There was a spelling mistake in the original publication . A corre\u201cWe found liver biopsies were an essential component of the IAIHG scoring system and that specific liver biopsy features including interface hepatitis and predominant plasma cells were significantly associated with AIH.\u201dDiscussion, the newly added sentence appears below.There was a missing part in the original publication . A corre\u201cHowever, a detailed look at the data published from many studies suggested that these two features carry a lower sensitivity due to difficulties in being identified or determined by light microscopy. Further study using immunostaining of CD8 T cells, along with confocal or electron microscopy, may help to assess the importance of emperipolesis.\u201dThe authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "In the graph second from the top, MAGE-A1 LTQ/A1 is indicated in black, but instead this should be MAGE-A1 KVL/A2.This error has been corrected in the figure online, and the authors apologize for any confusion this may have caused."}
{"text": "Error in FigureDue to problems with The authors wish to replace The authors wish to replace The authors state that the scientific conclusions are unaffected. This correction was approved by the academic editor. The original publication has also been updated."}
{"text": "J Clin Invest. 2022;132(18):e161400. https://doi.org/10.1172/JCI161400Original citation: J Clin Invest. 2023;133(11):e172059. https://doi.org/10.1172/JCI172059Citation for this corrigendum: After the publication of this paper, the authors became aware of errors in data analysis due to an issue with the barcoding of samples that caused some samples to be excluded. The authors have repeated all of the analysis and corrected Supplemental Figures 5, 6, and 9. The supplemental file has been updated online.The authors regret the errors."}
{"text": "Correction: Reproductive Health (2023) 20:4 https://doi.org/10.1186/s12978-022-01559-8After publication of this article , the autThis study was supported by ICES, which is funded by an annual grant from the Ontario Ministry of Health (MOH) and the Ministry of Long-Term Care (MLTC). Parts of this material are based on data and information compiled and provided by the MOH. The analyses, conclusions, opinions, and statements expressed herein are solely those of the authors and do not reflect those of the funding or data sources; no endorsement is intended or should be inferred. Parts of this material are based on data and information provided by Ontario Health (OH). The opinions, results, view, and conclusions reported in this paper are those of the authors and do not necessarily reflect those of OH. No endorsement by OH is intended or should be inferred. Parts of this material are based on data and information compiled and provided by CIHI. The analyses, conclusions, opinions and statements expressed herein are solely those of the authors and do not reflect those of the funding or data sources; no endorsement is intended or should be inferred. Parts or whole of this material are based on data and/or information compiled and provided by Immigration, Refugees and Citizenship Canada (IRCC). However, the analyses, conclusions, opinions and statements expressed in the material are those of the author(s), and not necessarily those of IRCC. The authors would like to acknowledge Wenbin Li at ICES Queen\u2019s for assistance with additional statistical analysis.The original article  has been"}
{"text": "Correction to: Circular Economy and Sustainabilityhttps://doi.org/10.1007/s43615-023-00265-2The original article has been corrected as the names of the last two authors were mistyped. The names of the last two authors were corrected from Mohammad Treiblmaier and Mohamad Iranmanesh to Horst Treiblmaier and Mohammad Iranmanesh"}
{"text": "Retraction Note: Cellular Oncology (2021) 44:1425\u2013143710.1007/s13402-021-00651-8The Editors-in-Chief have retracted this article at the authors\u2019 request. After publication, the authors contacted the journal requesting a correction to Figs.\u00a04 and 5 due to image overlap with their other article, specifically:Figure\u00a04d 48\u00a0h IFIT1 image appears highly similar to Fig.\u00a07f Huh7 48\u00a0h control in [Figure\u00a05c Aspc-1 si-IFIT1 image appears highly similar to Fig.\u00a07h Huh7 si-METTL18 in [Figure\u00a05a and c Aspc-1 si-IFIT1 images appear to overlap.Further checks by the Publisher found several additional cases of image overlap in Figs.\u00a02, 4 and 5, as well as other similarities between Figs.\u00a04 and 7 in this article and Fig.\u00a07 in . The autThe authors have been invited to resubmit a corrected version of the article for peer review.All authors agree to this retraction."}
{"text": "After careful investigation by the authors, it has been determined that the specimens shown are identical, albeit with a slight difference in the region of interest. The authors sincerely regret this oversight and would like to emphasize that it was a genuine error and in no way intentional. The authors have carefully reviewed their stored data and experimental notebooks, and in the process, it was found that the image of Gdnf-KO #2 had been used incorrectly. Due to the age of the article, the original figure cannot be replaced, but the revised figure is shown below for readers. This revised Figure\u00a05 replaces the original, incorrect image of Gdnf-KO #2 with the correct one. The authors would like to assure readers that this error does not affect the conclusions of the study. They deeply regret any confusion this may have caused and appreciate the understanding of the scientific community."}
{"text": "Trianthema portulacastrum Linn. on dermal wounds via removal of oxidative stress and inflammation\u2019 by Ekta Yadav et al., RSC Adv., 2018, 8, 21621\u201321635, https://doi.org/10.1039/C8RA03500H.Correction and removal of expression of concern for \u2018Ameliorative effect of biofabricated ZnO nanoparticles of  The authors regret that there was an error in This correction supersedes the information provided in the Expression of Concern related to this article.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Open Biol.10, 190286. (Published online 13 May 2020). (doi:10.1098/rsob.190286)Following the publication of \u2018Long non-coding RNA LINC00346 contributes to cisplatin resistance in nasopharyngeal carcinoma by repressing miR-342-5p\u2019, the Editorial team have concerns regarding the validity of the data used in this study.We are issuing an expression of concern here and investigating this as a matter of urgency; we will notify readers as to the results of our investigation as soon as possible."}
{"text": "CA and SE organized the database. CA, MD, and MoM performed the statistical analysis. CrC wrote the first draft of the manuscript. CrC, MD, CG, and MiM wrote sections of the manuscript. MD, CG, and MiM collected data. All authors contributed to manuscript revision, read, and approved the submitted version\u201d.The correct spelling is CCr, GC, RL, VB, and CCo contributed to conception and design of the study. AC and ES organized the database. AC, DM, and MMo performed the statistical analysis. CCr wrote the first draft of the manuscript. CCr, DM, GC, and MMi wrote sections of the manuscript. DM, GC, and MMi collected data. All authors contributed to manuscript revision, read, and approved the submitted version.In the published article, author names were incorrectly written in Conflict of interest section as \u201cCA has received research grants from Almirall, research grants from ECTRIMS-MAGNIMS and honoraria from Almirall, Biogen, Roche Sanofi-Genzyme and Novartis. MoM has received research grants from ECTRIMS-MAGNIMS, UK MS Society, and Merck; and honoraria from Biogen, Merck, Roche, and Sanofi-Genzyme. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest\u201d.The correct spelling is AC has received research grants from Almirall, research grants from ECTRIMS-MAGNIMS and honoraria from Almirall, Biogen, Roche Sanofi-Genzyme and Novartis. MMo has received research grants from ECTRIMS-MAGNIMS, UK MS Society, and Merck; and honoraria from Biogen, Merck, Roche, and Sanofi-Genzyme. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.The authors apologize for this error and state that this does not change the scientific conclusions of the article in anyway. The original article has been updated."}
{"text": "Chemosensitivity studies havebeen conducted against human pancreatic carcinoma (MIA PaCa-2), humancolorectal adenocarcinoma p53-wildtype (HCT116 p53+/+) and normal human retinal epithelial celllines (APRE-19). The most active complex, which contains a 2-furan-substitutedligand (4), is 5x more cytotoxic than the analogs 3-furancomplex (5) against MIA PaCa-2. Several complexes werescreened under hypoxic conditions and at shorter-time incubations,and their ability to damage DNA was determined by the comet assay.Compounds were also screened for their potential to inhibit the growthof both bacterial and fungal strains.The synthesis and characterization of 24 ruthenium(II)arene complexesof the type [( Tuning the ligand environment andmetal oxidation states can help control the thermodynamic and kineticproperties of the complexes in order to control their biological activity.3 Therefore, ruthenium research has produced aplethora of potential therapeutics with a wide range of structures,geometries, and oxidation states and easily tunable ligand environments.Ruthenium is relatively well toleratedby the body,5 andthis stemmed from the promising cytotoxicity of Ru(III) compoundsNAMI-A (ImH)[trans-RuCl4(DMSO)(Im)] (trans-RuCl4(Ind)2], Ind = indazolium) (6 Such ruthenium complexeshave different modes of action than cisplatin (CDDP), including theability to target cancer cells that are resistant to platinum treatment.7Over the last two decades, there has been a surge in anticancerresearch for ruthenium coordination compoundsazolium) 1B.6 Such0/+  RuCl(en)][PF6] (RM175),9 which has multiple binding modes to nucleic acids,10l-cysteine, and methionine.11 Complexes were inactive with N,O-chelating ligands, whereascomplexes containing an O,O-chelating acetylacetone  arene complexes with different ligand-bindingmodes whereby \u03b2-ketoiminate N,O-bound ligands are considerablymore effective than N,N-picolinamide and O,O-acetylacetone-type ligandsfollowing the trend N,O > N,N > O,O.14To date, Ru(II) organometallic \u201cpiano stool\u201dcomplexesof the type [(arene)RuX(L)]ligand) 1Cmake u16 Ferrocenyl-based compounds can act as \u201credox antennas\u201d,aiding in the formation of reactive oxygen species (ROS) and leadingto DNA damage.17 We have recently shownthat the incorporation of ferrocene into \u03b2-diketonate ligandsto synthesize functionalized ferrocenyl \u03b2-diketonate ligands2(Fc-acac)Ru][PF6]  and human colorectalcarcinoma p53-wildtype (HCT116 p53+/+) cell lines with dose-dependent double-strand DNAdamage, which is correlated to their cytotoxicity.Heterobimetallic species have the potentialbenefit of both metalsworking together, and by combining ruthenium and ferrocene into asingular complex, it is possible to have synergistic effects againstcancer cells.p-cymene (p-cym) or 1,2,3,4,5-pentamethylcyclopentadiene(Cp*) and Fc-acac = a functionalized ferrocenyl \u03b2-diketonateligand with either a methyl or trifluoromethyl group  piano-stool complexesof the type [(arene)RuCl(Fc-acac)], where arene = yl group 1G.22 The1 and 7).22 This includes the analysis of 21 new molecular structures via single-crystalX-ray diffraction (sc-XRD). All compounds have been screened for theircytotoxic potential using the MTT assay against MIA PaCa-2 and HCT116 p53+/+ cancer cell lines and a normal human retinalepithelium cell line, ARPE-19. Additional studies were conductedon the ligand and complex stability by NMR spectroscopy, intracellularmetal uptake by ICP-MS, cyclic voltammetry to assess accessible redoxpotentials, cytotoxicity under severe hypoxic (0.1% O2)conditions at shorter exposure times, and double-strand breakages(DSB) of DNA using the comet assay. The compounds have also been screenedfor their potential to inhibit the growth of several bacterial andfungal strains.We have extendedthe library of Ru(II) piano-stool complexes toinclude 22 new complexes and the two recently reported complexes byManikandan et al. . The p-cymene Ru(II) ferrocenyl \u03b2-diketonatecomplexes, [(p-cym)RuCl(Fc-acac)] 1\u201324, were preparedby adaptations of previously published methods,14 whilst 1 and 7 have been recentlyreported.22 A functionalized ferrocenyl\u03b2-diketonate ligand (2 eq.) was stirred at room temperatureovernight with triethylamine (2 eq.) and [(p-cym)RuCl2]2 (1 eq.) in dichloromethane RuCl(Fc-acac)] complexes have ashift in the ferrocenyl protons to lower frequencies. Due to the introductionof a chiral center and a loss of symmetry caused by the restrictedrotation of the top Cp ring , the resonances for free ligand appear as two 2H broad triplets(ca. 4.75 and 4.50 ppm) which move to two 1H doubletof triplets (ca. 4.80 and 4.58 ppm) and two 1H tripletof doublets (ca. 4.35\u20134.30 ppm).The ferrocenyl \u03b2-diketonateligands (Fc-acac) were synthesized using a Claisen condensation reactionand our previously reported literature methods.f 23\u201397% S1. The pL5, L8, L11, L13, L14, and L23  were obtained from slow evaporationof acetonitrile. Molecular structures were determined by sc-XRD analysis(Tables S1 and S2) with structural solutionsperformed in a tetragonal (L5), monoclinic (L8 and L13 and L14), orthorhombic (L11), or tetragonal (L23) space groups. All moleculesdisplay a planar structure with angles of 119\u2013122\u00b0 aroundthe enol/keto center (Tables S3 and S4)and the ferrocenyl group adopts an eclipsed geometry, as discussedin our previous work.18 In all cases, intramolecularhydrogen bonding is observed between enol\u2013keto with O\u2013H\u00b7\u00b7\u00b7Odistances ranging between 2.46 and 2.50 \u00c5 (D\u2013A), thusrestraining the geometry to a planar orientation.Red/orangesingle crystals of ligands 1, 2, 4\u20136, and 9\u201324  wereobtained from either the slow evaporation of acetonitrile or the vapordiffusion of dichloromethane/pentane at 4 \u00b0C. Sc-XRD analysis(Tables S5\u2013S10) was obtained, andsolutions were performed in monoclinic cells except for complexes 6 (orthorhombic) and 16 (triclinic). All rutheniumarene complexes adopt the expected pseudo-octahedral\u201cpiano stool\u201d geometries with the angles around theruthenium metal center in the range of 84\u201389\u00b0 (Tables S11 and S12). Intramolecular interactions(D\u00b7\u00b7\u00b7A = 3.4\u20134.0 \u00c5) are seen between the p-cymene isopropyl group and the chloride bound to the rutheniumcenter (C10/11\u2013H\u00b7\u00b7\u00b7Cl1) in all cases (except 6) with additional intermolecular interactions (D\u00b7\u00b7\u00b7A= 3.2\u20134.0 \u00c5) observed in all complexes. These interactionscould explain the shift to a lower frequency for the p-cymene hydrogens, which was also observed in our previous arene-Ru(II)work.14Red/orangesingle crystals of complexes 1\u201324, cisplatin (CDDP),carboplatin (CARB), and oxaliplatin (OXA) using a 96 h MTT assay (Table S13). All compounds were screened againsthuman pancreatic carcinoma (MIA PaCa-2) and human colorectal adenocarcinoma p53-wildtype (HCT116 p53+/+).The results show that complexes display varying cytotoxicity towardboth cancer cell lines tested with a general increase in activityobserved against MIA PaCa-2. The 2-furan Fc-acac complex 4 exhibited the highest cytotoxicity  against MIA PaCa-2 followedby the trifluoromethyl Fc-acac complex 7 (IC50 = 11 \u00b1 1 \u03bcM). Although 4 exhibits the highestIC50 value against MIA PaCa-2, it has a significantly lowerpotency than the Ru(II) coordination analogues we have previouslyreported .21To deduce any structural\u2013activityrelationships (SARs), chemosensitivity studies were performed forcomplexes 1, which contains an unfunctionalizedFc-acacligand, has low activity against all cell lines (IC50 =92\u201393 \u03bcM), and highlights that functionalizing the methylwith electron-withdrawing groups improves the cytotoxicity. The additionof a phenyl substituent (2) increases the activity byca. 2-fold against MIA PaCa-2 (IC50 = 50 \u00b1 6 \u03bcM);however, by increasing the hydrophobicity further from phenyl (2) to naphthyl (3), the IC50 valuesdecrease and complex 3 is inactive against all cell lines(IC50 > 100 \u03bcM), confirming that the IC50 values do not correlate with the hydrophobicity. The hydrophobicityof each complex were obtained from an octanol\u2013water shake-flaskmethod, and the data is shown in Table S14. It should be noted that, when comparing the recent work of Manikandanet al., complexes 1 and 7 follow the sametrend22 whereby the activity of 7 > 1. However, their activities are significantlylowerthan those reported against HeLa , A2780 (ovarian) and A2780cisR(cisplatin resistant ovarian). This highlights potential selectivitytoward these cell lines and highlights the need for further screeningof our library against a wider range of cancerous cells.Complex 1\u201324 (Table S13) wherebyall compounds were non-toxic toward this cell line at the maximumtested concentrations (>100 \u03bcM), demonstrating excellentchemoselectivitytoward the cancer cell lines MIA PaCa-2 and HCT116 p53+/+. This contrasts with CDDP and OXA, which remain cytotoxictoward normal cell lines; IC50 = 6 \u00b1 1 \u03bcM and3.0 \u00b1 0.3 \u03bcM, respectively. The IC50 valueshave been expressed as a selectivity index (SI), which are calculatedby dividing the IC50 value against the normal cell lineby the IC50 value against the cancer cell line (Table S13). SI > 1 indicates selectivity forthe cancer cell line over the normal cell line ARPE-19. Unlike OXA,which is selective for HCT116 p53+/+ (SI= 3.2), complexes 1\u201324 have low selectivitytoward this cell line with SI values ranging from 1.0 to 2.1. Whenanalyzing the SI values for all complexes against MIA PaCa-2, thereis greater selectivity than both CDDP (SI = 1.7) and OXA (SI = 1.0)with SI values of up to 12.7 for complex 4 . Several changes were observed for all complexes, which includesthe darkening of the samples from red to brown and bathochromic orhypo/hyperchromic shifts. The UV\u2013vis spectra are assigned tentativelyfrom TD-DFT calculations on similar structures.25 In most complexes(except 6 and 7), there is a hyperchromicshift of a newly formed MLCT band in the region of 330\u2013370nm and ligand-based absorbance at 220\u2013230 nm. These changesin the spectral properties of the complexes strongly suggest thatthere are changes to the Ru\u2013Cl bond but they are not conclusive.To assign the structural changes, 1H NMR spectroscopy wasmeasured first in DMSO-d6 and then in90% DMSO-d6/10% D2O . Attemptswere made to increase the water content (>10%) of the samples;however,a significant amount of complex precipitation was observed, affectingthe overall concentrations and impeding a full analysis.To understand the lack of activityin our complexes, the stability has been assessed by UV\u2013visspectroscopy in 10% H1, 2, 4 and 7 and thecorresponding ferrocenyl \u03b2-diketonate ligands L1, L2, L4 and L7 were analyzedafter initial (ca. 5 min), 20 and 40 min and then between 1 and 96h at 293 K (ca. 5 mg/mL). On analysis of the ferrocenyl ligands inboth 100% DMSO-d6 and 90% DMSO-d6/10% D2O, complete decompositionis observed by ca. 12 h to give free Cp (6.5 ppm) and a paramagneticspecies. The speed at which decomposition happens is faster in thepresence of 10% D2O. When comparing complexes 1, 2, 4, and 7 to the correspondingligands L1, L2, L4, and L7 after 96 h, the stability of the complexes is enhanced,where although some free Cp is generated, it is slower than the ligandalone.Complexes d6, complexes 2 and 4 are the most stable and do not changeover 96h, whereas complexes 1 and 7 show some decompositionto free p-cymene, which is observed in the new signalsat 7.10, 2.95, 2.22, and 1.16 ppm . When analyzed in the presence of 10% D2O, all complexesdecompose by 96 h to free p-cymene, free Cp, anda paramagnetic species. It should be also noted that, unlike the workreported by Manikandan et al.,22 we donot observe an aqua species, which is likely due to rapid exchange.To further assess this, we have conducted NMR studies of complex 1 in the presence of 100 mM NaCl , and decomposition to free p-cymene and Cp still occurs but to a lower degree.In 100% DMSO-1, 2, 4 and 7 and their corresponding ferrocenyl \u03b2-diketonate ligands L1, L2, L4 and L7 havebeen assessed after MIA PaCa-2 cells were treated for 48 h with 10\u03bcM of each compound. To understand the cytotoxicity relationships,MTT assays of all compounds were conducted after 48 h of incubation(Table S15). The cytotoxicity of the ligandsfollows the order L7 > L4 > L1 \u2248 L2, while the uptake of Fe followsthe oppositetrend whereby L7 has the lowest uptake of 1536 \u00b1202 ng Fe/106 cells (6 cells). The least active ligands L1 and L2 have a higher uptake of 2661 \u00b1974 ng Fe/106 cells and 2524 \u00b1 458 ng Fe/106 cells, respectively.It has been reported that cytotoxicitycan be related to the uptake of compounds into the cell. The uptakeof complexes 4 (IC50 = 23 \u00b1 2 \u03bcM)and 7 (IC50 = 30 \u00b1 1 \u03bcM) have similaractivity; however, their uptake is very different, suggesting differentmodes of action. Complex 4 has overall the lowest uptakeof 1264 \u00b1 229 ng Fe/106 cells and 281 \u00b1 82 ngRu/106 cells, which is not significant when compared tothe control alone. It should be noted that the uptake of complex 7 (6077 \u00b1 119 ng Fe/106 cells and 8388 \u00b1369 ng Ru/106 cells) is significantly enhanced when comparedto the corresponding ligand, where the intracellular Fe content isincreased by approximately 4-fold. While there is no correlation betweenthe cytotoxicity and uptake of these compounds, the binding of theferrocenyl \u03b2-diketonate ligands to the Ru(II) center does increasethe cellular uptake, and this is possibly linked to the complexesincreased stability, which we also observed in the NMR studies.When considering the cytotoxicity of the complexesafter 48 h,complexes + redox couple.17 Totest that the redox potential is within a biological relevant region,cyclic voltammetry (CV) experiments are conducted on complexes 1, 2, 4, and 7 andtheir corresponding ferrocenyl \u03b2-diketonate ligands L1, L2, L4, and L7 for reference.All complexes exhibit a rich redox chemistry with several oxidationand reduction peaks in the scanned region between \u22122.1 and1.65 V . The discussion is focused on the metal-based redoxprocesses, and a full analysis of the CV can be found in the Supporting Information.Ferrocene-containing compounds arewell known to exhibit cytotoxicity due to the formation of ROS, duethe Fe/Fe+ redoxcouple. When compared to ferrocene (0.40 V against SCE), the redoxpotential is shifted to more positive values due to the electron-withdrawingeffect of the \u03b2-diketonate functionality, which is in line withpreviously reported ferrocenyl functionalized ruthenium arene complexes.26 Substitution of the methyl group (1) with phenyl (2) or 2-furan (4) has onlya negligible effect on the potential in both the ligands and complexes.However, the introduction of a trifluoromethyl moiety (7) shifts the potential to more positive values in line with its stronglyelectron-withdrawing character. The potentials shift by 0.08 and 0.10V for the ligand and complex, respectively.All compounds exhibit a reversible single-electronoxidation between0.53 and 0.71 V, which is assigned to the Fc*/Fc*7 increases the redox stability of the Ru(II) centerto a higher degree.The CVs of all complexesexhibit an irreversible oxidation in theregion of 1.29\u20131.48 V with a similar trend as discussed forthe ferrocenyl redox couple assigned to the irreversible oxidationof Ru(II) to Ru(III). Therefore, electronic communication betweenthe substituents on the ferrocenyl \u03b2-diketonate ligands andthe Ru center exists; hence, the electron-withdrawing substituentin 27 and hypoxiccellular environments, these are only discussed in the Supporting Information.28 A similar conclusion is drawn for the irreversible Ru(II) to Ru(III)oxidation. In contrast, the reversible Fc*/Fc*+ redox couplesare within a reasonable region to induce ROS, suggesting that sucha mode of action might contribute to the overall cytotoxicity. Nocorrelation between the complexes\u2019 CV\u2019s and their cytotoxicityis found, indicating that other possible modes of actions highly likelycontribute significantly to the overall toxicity.Irreversible reductions tentatively assignedto the ferrocenyl\u03b2-diketonate ligands are observed in the region between \u22121.42and 1.98 V. Since these reductions are too far shifted to lower potentialsto be relevant in both normoxic29 Hypoxic cellsare well known to be resistant toward chemotherapy and radiotherapytreatments, leading to great challenges in finding suitable cancertherapeutics.30 In particular, reducingenvironments associated with hypoxia can cause difficulties for transitionmetals as a change in their oxidation state can lead to a change intheir structure, binding mode, cellular drug uptake, and metabolismand even reduce the effectiveness of their cellular mechanism of actionor change it completely.31Cancer cells have areas with extremelylow oxygen concentrations, which is referred to as hypoxia, whichleads to a reducing environment inside the cells. This environmentis due to the poor formation of new blood vessels during the rapidgrowth phase of the tumor.2). Complexes 4, 7, CDDP, andOXA were screened against MIA-PaCa-2 , and all show a decrease in cytotoxicity, including the clinicallyapproved compounds CDDP and OXA. Complex 7 experienceda 4-fold loss of activity from normoxic to hypoxic conditions ,while CDDP exhibited a significant loss of activity that was >14-fold.All compounds are considered inactive, and this may be due to no accessiblereduction available in the cellular environment. Possible reasonsfor the reduced activity under hypoxic conditions are the absenceof a reduction peak close to \u22120.241 V against the SCE (0 Vagainst the SHE), ruling out a redox-dependent activation as observedfor other ruthenium compounds like NAMI-A or KP101932 and no targeting of hypoxia-inducible factors as describedpreviously for Ru(II) arene complexes.34 A loss ofsuch activity has also been observed for the clinical platinum complexesCDDP and OXA under hypoxic conditions against a range of cell lines.38The influenceof the oxygen concentration upon the complex\u2019s potency wasassessed after 96 h of MTT assay in severe hypoxic conditions  of DNA with varyingconcentrations of compound was studied after incubation with MIA PaCa-2cells for 48 h. After harvesting the cells, quantification of thelevels of SSB of DNA were assessed by using the alkaline comet assay.Compounds 2 and 7 only show a small degreeof SSB when incubated for 48 h but increase in a dose-dependent mannerwith respect to an increase in the concentration  inwhich complex 4 exhibits the lowest IC50 valueand exhibits the highest degree of SSB in DNA. 50 value after 48 h, the following trend in activity was observed: 4 > 7 > 2, which is the sametrendobserved in the degree of DNA damage and highlights a strong correlationbetween the two assays. The same trend is not observed for CDDP, whichexhibits low cytotoxicity after 48 h (IC50 = 76 \u00b13 \u03bcM); however, exhibits dose-dependent SSB similar to thatof complex 4. While other mechanisms are likely to beinvolved, the induction of SSB provides a possible cause of the apoptoticphenotype induced by these compounds. Induction of SSB is common forcisplatin; however, we cannot confirm the modes of action of our compoundswithout a full in-depth analysis, including double-strand breakage(DSB) and cross-linking assays. Complex 4 shows impressiveDNA interactions when compared to the low cellular uptake measuredby ICP-MS ruthenium ferrocenyl\u03b2-diketonato complexes (Staphylococcus aureus (S. aureus).21 We have screened complexes 1\u201324 for their antibacterial activityagainst ESKAPE pathogens , moderate to low activity againstGram negative K. pneumoniae and A. baumanni (E. coli or P. aeruginosa (Table S19). Although there are few distincttrends, generally, the most active complexes against S. aureus contain a Fc-acac ligand with neutral inductivearomatic ring systems , or increasing the number of halides inthe structure  can increase the activity by approximately2-fold. Similar trends are observed for the position of the F-substitutedcomplexes, where 17 (para) > 15 (meta) > 14 (ortho) > 16 (di-meta). Interestingly,decreasingelectronegativity of the halogen atoms F > Cl > Br > I causesa decreasein the activity of the complexes when the halogen atom is locatedat the para position, yet an increase in activityof the complexes when the halogen atom is located at the meta position. The opposite observation is true for electron-donatingsubstituents  and suggests that the inductive effectsaround the aromatic ring may be responsible to some degree in impartingbacterial inhibition properties to the complexes. Complexes that wereclassified as active underwent HIT confirmation to determine theirminimum inhibitory concentration , and complexes 2 and 9 are classified as active with MIC values of 16 \u03bcg/mL.All complexes were initially screened at 32 \u03bcg/mL and exhibitsignificantly high activity toward Gram-positive baumanni 7A and no1\u201324, complexes 2 and 9 were also the only compounds found to be activeagainst the C. neoformans strain, withinhibition concentrations of 116 and 120%, respectively , yet they were all inactive with MIC values of >32 \u03bcg/mL.The complexes have varying toxicities toward normal kidney cells ; however, hemolysis (Hm) results wereextremely positive, and all complexes exhibited no potency towardhuman blood at the maximum tested concentration of 32 \u03bcg/mL,which is important for the distribution of these complexes in thebloodstream.When addressing the fungal growth inhibition after incubation withcomplexes ectively 7B.Complep-cymeneRu(II) complexes, [(p-cym)RuCl(Fc-acac)], containingfunctionalized ferrocenyl\u03b2-diketonate ligands (Fc-acac), are reported, including sc-XRDdetermination for 21 of the complexes. The complexes have been screenedagainst MIA PaCa-2, HCT116 p53+/+, andARPE-19 cell lines. The complexes are generally more active towardMIA PaCa-2 than HCT116 p53+/+ and exhibitno cytotoxicity against the normal cell line (IC50 >100\u03bcM). This is contrary to the clinical platinum drugs CCDP andOXA, which remain cytotoxic; IC50 values of 6 \u00b1 1\u03bcM and 6 \u00b1 3 \u03bcM, respectively. Complex 4 (R = 2-furan) exhibits the highest cytotoxicity of this library(IC50 = 8 \u00b1 2 \u03bcM) with a selectivity index (SI)of 12.5 against MIA PaCa-2.A library of 24 p-cymene and free Cp. This process is faster in the presence of waterbut slowed when 100 mM NaCl is added. Shortened-time exposure MTTand ICP-MS were used to study the uptake of the compounds into MIAPaCa-2 after 48 h. The highest uptake is not observed for the mostactive complexes and could be due to a lack of compound stability.UV\u2013vis and NMR studies highlightthe complexes\u2019 changeover 96 h, and while UV\u2013vis data show changes to the Ru\u2013Clbond, the NMR studies show decomposition to free + redox couple between 0.53 and 0.63 V (againstSCE), indicating that the formation of ROS is a reasonable mode ofaction. A correlation between the redox potential and cytotoxicityis not observed pointing out that further studies are necessary toassess the relevance of ROS to the overall toxicity. Complexes werealso tested under severely hypoxic (0.1% O2) conditionsagainst MIA PaCa-2; however, like CDDP, these complexes decrease inactivity and this could be due to inaccessible reduction potentials.Complexes 2, 4, and 7 werefurther tested for their ability to induce single-strand breakage(SSB) of DNA within MIA PaCa-2 cells with complex 4 exhibitingthe highest degree of damage, which is dose-dependent with respectto the concentration. The work highlights that complex 4 exhibits an impressive amount of DNA damage despite the lower concentrationof intracellular metal which was observed by ICP-MS. Further modificationsto this complex to improve cell uptake could therefore lead to significantlyenhanced cytotoxicity.Cyclic voltammetry studies are conducted revealing a reversibleFc*/Fc*S. aureus (83\u201395%),but no or low activity against Gram-negative strains. While the complexesshowed varying degrees of cytotoxicity toward HEK-293 cells, theyare all non-toxic towards human blood (HC10 > 32 \u03bcg/mL),which is important for the distribution of these complexes in thebloodstream.Finally, the growth inhibition of bacterialand fungal strains,human embryonic kidney (HEK-293) and hemolysis assays were conducted.The complexes have increased activity toward Gram-positive strains,for example, Supporting Information. Ligand L6 (\u00b10.54%) and complexes 8 (\u00b10.59%), 16 (\u00b10.60%), 18 (\u00b10.79), and 19 (\u00b10.43) have elemental analysis values slightly higherthan expected, and although these results are outside the range viewedas establishing analytical purity, they are provided to illustratethe best values obtained to date. To support the results, we haveprovided high-resolution mass spectrometry data, which are withinrange, and single-crystal X-ray diffraction analysis for complexes 16, 18, and 19 to prove that productswere achieved successfully.The general methods, instrumentation,synthesis/characterizationof the ligands, X-ray crystallography, and biological assays can befound in the p-cymRuCl2]2 (1 equiv). The mixture was stirredat room temperature overnight. The solvent was removed in vacuo andpurified by column chromatography using 3:2 v/v petrol/ethyl acetate to yield orange solids.14A functionalizedferrocenyl ligand (2 equiv) was dissolved in dichloromethane (20 mL)followed by addition of triethylamine (2 equiv) and  calculated for C24H27ClFeO2Ru: 540.009. Found: 505.042 [MH+]-Cl.Yield: 0.14 g, 68%. 1H NMR 2CO, \u03b4); 7.84  = 7.3 Hz, ortho ArC\u2013H), 7.33  = 7.3 Hz, para ArC\u2013H), 7.28  = 7.3 Hz, ortho ArC\u2013H), 6.04 , 5.55  = 6.4 Hz, p-cymene ArC\u2013H), 5.24  = 6.0 Hz, 4J(1H\u20131H) = 1.8 Hz, p-cymene ArC\u2013H), 4.83  = 1.2 Hz,\u2212CC4H4), 4.73 = 1.2 Hz, \u2212CC4H4), 4.32  = 2.2, 1.4 Hz, \u2212CC4H4), 4.28  = 2.3, 1.4 Hz, \u2212CC4H4), 4.11 , 2.91  = 6.9Hz, p-cymene \u2212CH(CH3)2), 2.16 , 1.34  = 7.3 Hz, p-cymene \u2212CH(CH3)2). 13C{1H} NMR 2CO, \u03b4); 186.8 (Q C\u2013O),178.4 (Q C\u2013O), 140.5 (Q Ar\u2013C), 131.2 (ortho Ar\u2013CH), 128.9 (meta Ar\u2013CH), 127.9 (para Ar\u2013CH), 99.4 (Q p-cymene \u2212CCH(CH3)2), 97.8 (Q p-cymene \u2212C(CH3)), 93.4 (methine\u2212COCHCO\u2212), 84.6 (p-cymene Ar\u2013CH), 84.5 (p-cymene Ar\u2013CH), 82.1 (Q Cp \u2212CC4H4), 80.0 (p-cymene Ar\u2013CH), 80.0 (p-cymene Ar\u2013CH), 71.7 (Cp \u2212CC4H4), 71.6 (Cp \u2212CC4H4), 70.9 (Cp \u2212C5H5), 69.9 (Cp \u2212CC4H4), 68.7 (Cp \u2212CC4H4), 31.7 (p-cymene \u2212CH(CH3)2), 22.7 (p-cymene \u2212CH(CH3)2), 22.6 (p-cymene \u2212CH(CH3)2), 17.9 (p-cymene \u2212C(CH3)). Analysiscalculated for C29H29ClFeO2Ru: C57.87, H 4.86, Cl 5.89%. Found: C 57.70, H 5.20, Cl 5.75%. HR-MS [ES+] calculated for C29H29ClFeO2Ru: 602.025. Found: 567.058 [MH+]-Cl.Yield: 0.21 g, 89%. 1H NMR2CO, \u03b4); 8.54  = 7.8 Hz, NpC2\u2013H), 7.82 = 8.0 Hz, NpC3\u2013H), 7.78 = 7.1 Hz, 4J(1H\u20131H) = 2.1 Hz, NpC3\u2013H), 7.45  = 7.1 Hz, NpC9\u2013H), 7.37 , 5.72 ,5.57  = 5.7 Hz, p-cymene ArC\u2013H), 5.53  = 5.9 Hz, p-cymeneArC\u2013H), 5.25  = 4.9 Hz, p-cymene ArC\u2013H), 4.83  = 0.7 Hz, Cp \u2212CC4H4), 4.62  = 0.9 Hz, Cp \u2212CC4H4), 4.33 , 4.27 , 4.14 , 2.86  = 6.9Hz, p-cymene \u2212CH(CH3)2), 2.09 ), 1.30  = 6.7 Hz, p-cymene \u2212CH(CH3)2). 13C{1H} NMR 2CO, \u03b4); 186.9 (Q C\u2013O),176.0 (Q C\u2013O), 156.4 (Q Np\u2013C1), 140.5 (Q Np\u2013C10), 134.9(Q Np\u2013C5), 132.0 (Np\u2013C2H), 130.2(Np\u2013C3H), 128.6 (Np\u2013C4H), 128.4(Np\u2013C9H), 126.8 (Np\u2013C6H), 125.7(Np\u2013C8H), 125.6 (Np\u2013C7H), 99.72), 98.3 (methine \u2212COCHCO\u2212), 97.7 ), 84.4 (p-cymene Ar\u2013CH), 84.2 (p-cymene Ar\u2013CH), 81.5 (Q Cp \u2212CC4H4), 80.1 (p-cymene Ar\u2013CH), 80.1 (p-cymene Ar\u2013CH), 71.9 (Cp \u2212CC4H4), 71.9 (Cp \u2212CC4H4), 71.0 (Cp \u2212C5H5), 69.9 (Cp \u2212CC4H4), 68.8 (Cp \u2212CC4H4), 31.6 (p-cymene \u2212CCH(CH3)2), 22.7 (p-cymene \u2212CCH(CH3)2), 22.6 (p-cymene \u2212CCH(CH3)2), 17.8 (p-cymene \u2212C(CH3)). Analysis calculated for C33H31ClFeO2Ru: C 60.79, H 4.79, Cl 5.44%. Found:C 60.70, H 4.90, Cl 5.20%. HR-MS [ES+] calculated for C33H31ClFeO2Ru: 652.041. Found: 617.074[MH+]-Cl.Yield: 0.21 g, 82%. 1H NMR 2CO, \u03b4); 7.53  = 0.9 Hz, Furan \u2212C(O)C3H3), 6.96  = 3.4 Hz, Furan \u2212C(O)C3H3), 6.44 = 3.7 Hz, 4J(1H\u20131H) = 1.6 Hz, Furan \u2212C(O)C3H3), 5.92 , 5.53  = 6.3 Hz, p-cymene ArC\u2013H), 5.20  = 5.7 Hz, p-cymene ArC\u2013H), 4.79  = 1.2 Hz, Cp \u2212CC4H4), 4.60  = 1.2 Hz, Cp \u2212CC4H4), 4.32  = 2.5, 1.2 Hz, Cp\u2212CC4H4), 4.28 = 2.5 Hz, 4J(1H\u20131H) = 1.2 Hz, Cp \u2212CC4H4), 4.11 , 2.88  = 6.9 Hz, p-cymene\u2212CH(CH3)2, H8), 2.14 ), 1.33  = 6.9 Hz, p-cymene \u2212CH(CH3)2). 13C{1H} NMR 2CO, \u03b4); 186.6 (Q C\u2013O),168.6 (Q C\u2013O), 163.6 (Q Furan \u2212C(O)C3H3), 145.0(Furan \u2212C(O)C3H3), 113.3 (Furan \u2212C(O)C3H3), 112.9 (Furan \u2212C(O)C3H3), 99.2(Q p-cymene \u2212CCH(CH3)2), 97.9 ), 92.3 (methine \u2212COCHCO\u2212), 84.8 (p-cymene Ar\u2013CH), 84.5 (p-cymene Ar\u2013CH), 81.9 (Q Cp \u2212CC4H4), 79.9 (p-cymene Ar\u2013CH7), 79.8 (p-cymene Ar\u2013CH), 71.7 (Cp \u2212CC4H4), 71.7 (Cp \u2212CC4H4), 70.9 (Cp \u2212C5H5), 69.9 (Cp \u2212CC4H4), 68.6 (Cp \u2212CC4H4), 31.7 (p-cymene \u2212CCH(CH3)2), 22.7 (p-cymene \u2212CCH(CH3)2), 22.6 (p-cymene \u2212CCH(CH3)2), 17.7 (p-cymene \u2212C(CH3)). Analysis calculated for C27H27ClFeO3Ru: C 54.79, H 4.60, Cl 5.99%. Found:C 55.05, H 4.60 Cl 5.99%. HR-MS [ES+] calculated for C27H27ClFeO3Ru: 592.004. Found: 557.036[MH+]-Cl.Yield: 0.20 g, 86%. 1H NMR 2CO, \u03b4); 8.19 C2H2), 7.60  = 1.6 Hz, Furan \u2212CH(O)C2H2), 6.90 = 1.2 Hz, Furan \u2212CH(O)C2H2), 5.97 , 5.68  = 6.1 Hz, p-cymene ArC\u2013H), 5.35  = 5.3 Hz, p-cymene ArC\u2013H), 4.96  = 1.2 Hz, \u2212CC4H4), 4.84  = 1.2 Hz, \u2212CC4H4), 4.44 , 4.40 , 4.25 , 3.04  = 6.9 Hz, p-cymene\u2212CCH(CH3)2), 2.29), 1.49  = 6.9 Hz, 4J(1H\u20131H) = 0.9 Hz, p-cymene \u2212CCH(CH3)2). 13C{1H} NMR 2CO, \u03b4); 186.0 (Q C\u2013O),173.6 (Q C\u2013O), 145.0 (Furan \u2212CCH(O)C2H2), 144.4(Furan \u2212CCH(O)C2H2), 128.8 (Q Furan \u2212CCH(O)C2H2), 109.8 (Furan \u2212CCH(O)C2H2), 99.2(Q p-cymene \u2212CCH(CH3)2), 97.8 (Q p-cymene \u2212C(CH3)), 94.0 (methine \u2212COCHCO\u2212), 84.7 (p-cymene Ar\u2013CH), 84.5 (p-cymene Ar\u2013CH), 82.0 (Q Cp \u2212CC4H4), 79.9 (p-cymene Ar\u2013CH), 79.8 (p-cymene Ar\u2013CH), 71.5 (Cp \u2212CC4H4), 71.5 (Cp \u2212CC4H4), 70.9 (Cp \u2212C5H5), 69.8 (Cp \u2212CC4H4), 68.6 (Cp \u2212CC4H4), 31.7 (p-cymene \u2212CCH(CH3)2), 22.7 (p-cymene \u2212CCH(CH3)2), 22.6 (p-cymene \u2212CCH(CH3)2), 17.7 (p-cymene \u2212C(CH3)). Analysis calculated for C27H27ClFeO3Ru: C 54.79, H 4.60, Cl 5.99%. Found:C 54.72, H 4.55, Cl 6.01%. HR-MS [ES+] calculated for C27H27ClFeO3Ru: 592.004. Found: 557.043[MH+]-Cl.Yield: 0.19 g, 81%. 1H NMR 2CO, \u03b4); 5.86  = 5.2 Hz, methine \u2212COCHCO\u2212),5.57  = 6.2 Hz, p-cymene ArC\u2013H), 5.56 , 5.22  = 5.6 Hz, p-cymeneArC\u2013H), 4.80 , 4.62 , 4.40 , 4.35 , 4.11 , 2.71  = 5.9Hz, p-cymene \u2212CCH(CH3)2), 2.09 ), 1.30  = 5.9 Hz, p-cymene \u2212CCH(CH3)2). 13C{1H} NMR 2CO, \u03b4); 190.1 (Q C\u2013O),172.8  = 22.1 Hz), 112.2 = 246.3 Hz), 99.5 (Q p-cymene \u2212CCH(CH3)2), 98.2 (Q p-cymene \u2212C(CH3)), 92.6 (methine \u2212COCHCO\u2212), 84.9 (p-cymene Ar\u2013CH), 84.2 (p-cymene Ar\u2013CH), 80.5 (Q Cp \u2212CC4H4), 79.9 (p-cymene Ar\u2013CH), 79.5 (p-cymene Ar\u2013CH), 72.7 (Cp \u2212CC4H4), 72.6 (Cp \u2212CC4H4), 71.2 (Cp \u2212C5H5), 70.1 (Cp \u2212CC4H4), 69.1 (Cp \u2212CC4H4), 31.7 (p-cymene \u2212CCH(CH3)2), 22.6 (p-cymene \u2212CCH(CH3)2), 22.5 (p-cymene \u2212CCH(CH3)2), 17.7 (p-cymene \u2212C(CH3)). Analysis calculated for C24H25ClF2FeO2Ru: C 50.06, H 4.38,Cl 6.16%. Found: C 50.30, H 4.40, Cl 6.30%. HR-MS [ES+]calculated for C24H25ClF2FeO2Ru: 575.990. Found: 541.023 [MH+]-Cl.Yield: 0.17 g, 77%. 1H NMR 2CO, \u03b4); 5.63 , 5.61  = 5.5 Hz, p-cymene ArC\u2013H), 5.30  = 5.5 Hz, p-cymene ArC\u2013H), 5.27 , 4.83  = 1.4 Hz,\u2212CC4H4), 4.68 = 1.4 Hz, \u2212CC4H4), 4.46 , 4.41 , 4.13 , 2.83  = 6.9 Hz, p-cymene\u2212CCH(CH3)2), 2.10), 1.17  = 7.3 Hz, p-cymene\u2212CCH(CH3)2). 13C{1H} 2CO,\u03b4); 218.9 (Q C\u2013O), 191.8 (Q C\u2013O), 99.5 (Q p-cymene \u2212CCH(CH3)2), 98.3 (Q p-cymene \u2212C(CH3)), 92.2 (methine\u2212COCHCO\u2212), 84.8 (p-cymene Ar\u2013CH), 84.2 (p-cymene Ar\u2013CH), 80.1 (Q Cp \u2212CC4H4), 79.5 (p-cymene Ar\u2013CH), 79.5 (p-cymene Ar\u2013CH), 73.5 (Cp \u2212CC4H4), 73.1 (Cp \u2212CC4H4), 71.3 (Cp \u2212C5H5), 70.9 (Cp \u2212CC4H4), 67.5 (Cp \u2212CC4H4), 31.8 (p-cymene \u2212CCH(CH3)), 22.5(p-cymene \u2212CCH(CH3)), 22.5 (p-cymene \u2212CCH(CH3)2), 17.7 (p-cymene \u2212C(CH3)). Analysiscalculated for C24H24ClF3FeO2Ru: C 48.54, H 4.07, Cl 5.97%. Found: C 48.90, H 4.10, Cl6.00%. HR-MS [ES+] calculated for C24H24ClF3FeO2Ru: 593.981. Found: 559.023 [MH+]-Cl.Yield: 0.20 g, 85%. 1H NMR 2CO, \u03b4); 7.79 , 7.75, 7.29 , 6.15 , 5.68  = 4.9, 4J(1H\u20131H) = 1.5 Hz, p-cymeneArC\u2013H), 5.36  = 4.9 Hz, 4J(1H\u20131H) = 1.5 Hz, p-cymene ArC\u2013H), 4.96  = 1.2 Hz, \u2212CC4H4), 4.84  = 1.2 Hz, \u2212CC4H4), 4.44 , 4.40 , 4.24 , 3.04  = 6.9 Hz, p-cymene\u2212CCH(CH3)2, H8), 2.42 , 2.29 ), 1.47  = 7.1 Hz, p-cymene\u2212CCH(CH3)2). 13C{1H} NMR 2CO, \u03b4); 186.6 (Q C\u2013O), 178.6(Q C\u2013O), 140.5 (Q Ar\u2013C), 138.4 (Q Ar\u2013C(CH3)), 131.8 (ortho Ar\u2013CH), 128.8 (ortho Ar\u2013CH), 128.5 (para Ar\u2013CH), 125.1 (ortho Ar\u2013CH), 99.4 2), 97.8 (Q p-cymene\u2212C(CH3)), 93.4 (methine \u2212COCHCO\u2212), 84.6 (p-cymene Ar\u2013CH), 84.5 (p-cymene Ar\u2013CH), 82.1 (Q Cp \u2212CC4H5), 80.0 (p-cymene Ar\u2013CH), 80.0 (p-cymene Ar\u2013CH), 71.6 (Cp \u2212CC4H4), 71.6 (Cp \u2212CC4H4), 70.9 (Cp \u2212C5H5), 69.9 (Cp \u2212CC4H4), 68.7 (Cp \u2212CC4H4), 31.7 (p-cymene \u2212CCH(CH3)2), 22.7 (p-cymene \u2212CCH(CH3)2), 22.6 (p-cymene \u2212CCH(CH3)2), 21.5 (meta Ar\u2013C(CH3)), 17.8 (p-cymene \u2212C(CH3)). Analysis calculated for C30H31ClFeO2Ru: C 58.50, H 5.07, Cl 5.76%. Found:C 57.91, H 5.06, Cl 5.82%. HR-MS [ES+] calculated for C30H31ClFeO2Ru: 616.041. Found: 581.072[MH+]-Cl.Yield: 0.23 g, 93%. 1H NMR 2CO, \u03b4); 7.45 , 6.98,6.01 ,5.54  = 4.0 Hz, p-cymene ArC\u2013H), 5.22  = 4.4 Hz, p-cymeneArC\u2013H), 4.82 , 4.69 , 4.30 , 4.26 , 4.10 , 2.90  = 6.9Hz, p-cymene \u2212CCH(CH3)2, H8), 2.21 ), 2.16 ), 1.34  = 6.9 Hz, p-cymene \u2212CCH(CH3)2). 13C{1H} NMR 2CO, \u03b4); 185.5(Q C\u2013O), 178.0 (Q C\u2013O), 139.6 (Q Ar\u2013C), 137.4 (Q meta Ar\u2013C), 131.7 (para Ar\u2013CH), 124.9 (ortho Ar\u2013CH), 124.5 (ortho Ar\u2013CH), 98.5 (Q p-cymene \u2212CCH(CH3)2), 96.9 (Q p-cymene \u2212C(CH3)), 92.5 (methine \u2212COCHCO\u2212), 83.8 (p-cymene Ar\u2013CH), 83.6 (p-cymene Ar\u2013CH), 81.3 (Q Cp \u2212CC4H4), 79.1 (p-cymene Ar\u2013CH), 79.0 (p-cymene Ar\u2013CH), 70.7 (Cp \u2212CC4H4), 70.6 (Cp \u2212CC4H4), 70.0 (Cp \u2212C5H5), 69.0 (Cp \u2212CC4H4), 67.8 (Cp \u2212CC4H4), 30.8 (p-cymene \u2212CCH(CH3)2), 22.7 (p-cymene \u2212CCH(CH3)2), 22.6 (p-cymene \u2212CCH(CH3)2), 20.6 (meta Ar\u2013C(CH3)), 17.9 (p-cymene \u2212C(CH3)). Analysis calculated for C31H33ClFeO2Ru: C 59.10, H 5.28, Cl 5.63%. Found: C 59.30, H5.30, Cl 5.50%. HR-MS [ES+] calculated for C31H33ClFeO2Ru: 630.056. Found: 595.090 [MH+]-Cl.Yield: 0.20 g, 80%; 1H NMR 2CO, \u03b4); 7.74  = 8.3 Hz, ortho ArC\u2013H), 7.10  = 7.8 Hz, meta ArC\u2013H), 6.02 ,5.54  = 6.0 Hz, p-cymene ArC\u2013H), 5.22  = 6.0 Hz, p-cymeneArC\u2013H), 4.82  = 1.2 Hz, Cp \u2212CC4H4), 4.71  = 1.2 Hz,Cp \u2212CC4H4), 4.30, 4.27 , 4.11 , 2.90  = 6.9 Hz, p-cymene\u2212CCH(CH3)2), 2.24), 2.16 ), 1.34  = 6.9 Hz, p-cymene \u2212CCH(CH3)2). 13C{1H} 2CO, \u03b4); 186.4 (Q C\u2013O), 178.4 (Q C\u2013O),141.4 (Q Ar\u2013C), 137.7 (Q para Ar\u2013C), 129.6 (ortho Ar\u2013CH), 127.9 (meta Ar\u2013CH), 99.4 (Q p-cymene \u2212CCH(CH3)2), 97.8 (Q p-cymene \u2212C(CH3)), 93.0 (methine \u2212COCHCO\u2212), 84.7 (p-cymene Ar\u2013CH), 84.5 (p-cymene Ar\u2013CH), 82.2 (Q Cp \u2212CC4H4), 79.9 (p-cymene Ar\u2013CH), 71.6 (Cp \u2212CC4H4), 71.5 (Cp \u2212CC4H4), 70.9 (Cp \u2212C5H5), 69.9 (Cp \u2212CC4H4), 68.6 (Cp \u2212CC4H4), 31.7 (p-cymene \u2212CCH(CH3)2), 22.7 (p-cymene \u2212CCH(CH3)2), 22.6 (p-cymene \u2212CCH(CH3)2), 21.4 (para Ar\u2013C(CH3)), 17.8 (p-cymene \u2212C(CH3)). Analysis calculated for C30H31ClFeO2Ru: C 58.50, H 5.07, Cl 5.76%. Found:C 58.60, H 5.10, Cl 5.80%. HR-MS [ES+] calculated for C30H31ClFeO2Ru: 616.041. Found: 581.072[MH+]-Cl.Yield: 0.18 g, 75%. 1H NMR 2CO, \u03b4); 7.55 , 7.54 = 7.8 Hz, ortho ArC\u2013H), 7.34  = 8.1 Hz, meta ArC\u2013H), 7.06  = 7.3 Hz, 4J(1H\u20131H) = 1.7 Hz, para ArC\u2013H), 6.17 ,5.72  = 2.4 Hz, p-cymene ArC\u2013H), 5.39  = 2.4 Hz, p-cymeneArC\u2013H), 4.99 , 4.89 , 4.47 = 0.9 Hz, Cp \u2212CC4H4), 4.43  = 0.9 Hz, Cp CC4H4), 4.27 , 3.89 ), 3.07  = 6.7 Hz, p-cymene \u2212CCH(CH3)2, H8), 2.33 ), 1.50  = 6.9 Hz, 4J(1H\u20131H) = 1.6 Hz, p-cymene \u2212CCH(CH3)2). 13C{1H} 2CO, \u03b4); 186.9 (Q C\u2013O), 178.1 (Q C\u2013O),160.6 (Q meta Ar\u2013C(OCH3)), 142.0 (Q Ar\u2013C), 129.9 (ortho Ar\u2013CH), 120.1 (ortho Ar\u2013CH), 116.9 (para Ar\u2013CH), 113.3 (meta Ar\u2013CH), 99.3 (Q p-cymene \u2212CCH(CH3)2), 97.9 (Q p-cymene \u2212C(CH2)), 93.5 (methine \u2212COCHCO\u2212), 84.7 (p-cymene Ar\u2013CH), 84.7 (p-cymene Ar\u2013CH), 82.1 (Q Cp \u2212CC4H4), 79.9 (p-cymene Ar\u2013CH), 79.9 (p-cymene Ar\u2013CH), 71.7 (Cp \u2212CC4H4), 71.7 (Cp \u2212CC4H4), 70.9 (Cp \u2212C5H5), 69.9 (Cp CC4H4), 68.8 (Cp \u2212CC4H4), 55.6 (meta Ar\u2013C(OCH3)), 31.7 (p-cymene \u2212CCH(CH3)2), 22.8 (p-cymene \u2212CCH(CH3)2), 22.6 (p-cymene \u2212CCH(CH3)2), 17.8 (p-cymene \u2212C(CH3)). Analysis calculated for C30H31ClFeO3Ru: C 57.02, H 4.94, Cl 5.61%. Found:C 57.09, H 4.90, Cl 5.53%. HR-MS [ES+] calculated for C30H31ClFeO3Ru: 632.036. Found: 597.068[MH+]-Cl.Yield: 0.20 g, 80%. 1H NMR 2CO, \u03b4); 7.83  = 9.2 Hz, 4J(1H\u20131H) = 2.8 Hz, ortho ArC\u2013H), 6.82  = 9.2 Hz, 4J(1H\u20131H) = 2.8 Hz, meta ArC\u2013H), 6.01 , 5.53  = 6.0 Hz, 4J(1H\u20131H) = 0.9 Hz, p-cymene ArC\u2013H), 5.21  = 6.4 Hz, p-cymene ArC\u2013H), 4.82  = 1.2 Hz, Cp \u2212CC4H4), 4.71  = 1.2 Hz, Cp \u2212CC4H4), 4.92 , 4.25 , 4.10 , 3.73 ),2.91  = 6.9 Hz, p-cymene \u2212CCH(CH3)2), 2.16 ), 1.34  = 7.3 Hz, p-cymene \u2212CCH(CH3)2). 13C{1H} NMR 2CO, \u03b4); 185.9(Q C\u2013O), 178.0 (Q C\u2013O), 162.7 (Q para Ar\u2013C(OCH3)), 132.8 (Q Ar\u2013C),129.7 (ortho Ar\u2013CH),114.2 (meta Ar\u2013CH),99.3 (Q p-cymene \u2212CCH(CH3)2), 97.8 (Q p-cymene\u2212C(CH3)), 92.6 (methine \u2212COCHCO\u2212), 84.6 (p-cymene Ar\u2013CH), 84.5 (p-cymene Ar\u2013CH), 82.4 (Q Cp \u2212CC4H4), 79.9 (p-cymene Ar\u2013CH), 79.9 (p-cymene Ar\u2013CH), 71.4 (Cp \u2212CC4H4), 71.4 (Cp \u2212CC4H4), 70.9 (Cp \u2212C5H5), 69.9 (Cp \u2212CC4H4), 68.6 (Cp \u2212CC4H4), 55.8 (para Ar\u2013C(OCH3)), 31.7 (p-cymene \u2212CCH(CH3)2), 22.7 (p-cymene \u2212CCH(CH3)), 22.6(p-cymene \u2212CCH(CH3)), 17.8 (p-cymene \u2212C(CH3)). Analysis calculated for C30H31ClFeO3Ru: C 57.02, H 4.94, Cl 5.61%. Found: C 57.00, H5.00, Cl 5.50%. HR-MS [ES+] calculated for C30H31ClFeO3Ru: 632.036. Found: 597.066 [MH+]-Cl.Yield: 0.22 g, 89%. 1H NMR 2CO, \u03b4); 7.82  = 8.9 Hz, ortho ArC\u2013H),6.80  = 8.9 Hz, meta ArC\u2013H), 6.00 ,5.53  = 4.8 Hz, 4J(1H\u20131H) = 1.2 Hz, p-cymene ArC\u2013H), 5.21  = 5.2 Hz, p-cymene ArC\u2013H), 4.82  = 1.2 Hz, Cp \u2212CC4H4), 4.70  = 1.2 Hz,Cp \u2212CC4H4), 4.29, 4.25 , 4.10 , 3.99  = 6.9 Hz, para ArC(OCH2CH3)), 2.90  = 6.9 Hz,\u2212CCH(CH3)2), 2.16), 1.33  = 6.9 Hz, p-cymene\u2212CCH(CH3)2) 1.26 = 6.9 Hz, para ArC(OCH2CH3)). 13C{1H} NMR 2CO, \u03b4); 185.8 (Q C\u2013O), 178.0 (Q C\u2013O),162.1 (Q para Ar\u2013C(OCH2CH3)), 132.6 (Q Ar\u2013C), 129.7 (ortho Ar\u2013CH), 114.7 (meta Ar\u2013CH), 99.3 (Q p-cymene \u2212CCH(CH3)2), 97.7 (Q p-cymene \u2212C(CH3)), 92.5 (methine\u2212COCHCO\u2212), 84.6 (p-cymene Ar\u2013CH), 84.5 (p-cymene Ar\u2013CH6), 82.4 (QCp \u2212CC4H4), 79.9(p-cymene Ar\u2013CH), 79.9(p-cymene Ar\u2013CH), 71.4(Cp \u2212CC4H4), 71.4(Cp \u2212CC4H4), 70.9(Cp \u2212C5H5), 69.8(Cp \u2212CC4H4), 68.6(Cp \u2212CC4H4), 64.2(para ArC(OCH2CH3)), 31.7 (p-cymene \u2212CCH(CH3)2), 22.8 (p-cymene \u2212CCH(CH3)2), 22.6 (p-cymene \u2212CCH(CH3)2), 17.9 (p-cymene \u2212C(CH3)), 15.0 (para ArC(OCH2CH3). Analysis calculated for C31H33ClFeO3Ru: C 57.64, H 5.15, Cl 5.49%. Found:C 57.65, H 5.25, Cl 5.40%. HR-MS [ES+] calculated for C31H33ClFeO3Ru: 646.051. Found: 611.085[MH+]-Cl.Yield: 0.19 g, 75%. 1H NMR 2CO, \u03b4); 7.87  = 7.7 Hz, 4J(1H\u201319F) = 1.2 Hz, ortho ArC\u2013H), 7.49 , 7.28  = 7.6 Hz, meta ArC\u2013H), 7.19  = 11.8 Hz, 4J(1H\u201319F) = 1.2 Hz, para ArC\u2013H), 6.02 , 5.71  = 4.8Hz, p-cymene ArC\u2013H),5.39  = 4.8 Hz, p-cymene ArC\u2013H), 4.93  = 0.8 Hz, Cp \u2212CC4H4), 4.75  = 0.9 Hz, Cp \u2212CC4H4), 4.49 , 4.45, 4.27 , 3.04  = 6.9 Hz, p-cymene\u2212CCH(CH3)2), 1.99), 1.48  = 6.9 Hz, p-cymene\u2212CCH(CH3)2). 13C{1H} 2CO,\u03b4); 187.1 (Q C\u2013O), 174.8  = 3.6 Hz), 160.6  = 250.1 Hz), 132.3  = 8.8 Hz), 131.7 =3.1 Hz), 129.3  = 11.9 Hz),125.1  = 3.6 Hz), 116.9  = 23.9 Hz), 99.5 (Q p-cymene \u2212CCH(CH3)2), 97.9  = 5.2 Hz), 97.8 (Q p-cymene\u2212C(CH3)), 84.5 (p-cymene Ar\u2013CH), 84.4 (p-cymene Ar\u2013CH), 81.7 (Q Cp \u2212CC4H4), 79.9 (p-cymene Ar\u2013CH), 71.9 (Cp \u2212CC4H4), 71.9 (Cp \u2212CC4H4), 71.1 (Cp \u2212CC5H5), 69.9 (Cp \u2212CC4H4), 68.8 (Cp \u2212CC4H4), 31.7 (pcymene \u2212CCH(CH3)2), 22.7 (p-cymene \u2212CCH(CH3)2), 22.6 (p-cymene \u2212CCH(CH3)2), 17.9 (p-cymene \u2212C(CH3)). Analysiscalculated for C29H28ClFFeO2Ru: C56.19, H 4.55, Cl 5.72%. Found: C 55.90, H 4.70, Cl 5.90%. HR-MS [ES+] calculated for C29H28ClFFeO2Ru: 620.016. Found: 585.049 [MH+]-Cl.Yield: 0.18 g, 72%. 1H NMR 2CO, \u03b4); 7.70  = 7.8 Hz, ortho ArC\u2013H),7.61  = 10.4 Hz, 4J(1H\u20131H) = 1.6, 0.9 Hz, ortho ArC\u2013H), 7.36 , 7.14  = 8.3 Hz, 4J(1H\u20131H) = 2.3 Hz, meta ArC\u2013H), 6.08 , 5.62  = 6.2 Hz, p-cymene ArC\u2013H), 5.29  = 4.7 Hz, p-cymene ArC\u2013H), 4.89  = 1.2 Hz, Cp \u2212CC4H4), 4.81  = 1.2 Hz, Cp \u2212CC4H4), 4.37 , 4.34 , 4.15 , 2.94  = 6.9Hz, p-cymene -CCH(CH3)2), 2.20 ), 1.38  = 7.1 Hz, p-cymene \u2212CCH(CH3)2). 13C{1H} NMR 2CO, \u03b4); 187.6 (Q C\u2013O),179.1 (Q C\u2013O), 164.6  = 243.9 Hz), 143.0  = 6.7 Hz), 130.8  = 8.3 Hz), 123.6  = 2.6 Hz), 117.7  = 21.3 Hz), 114.5  = 22.8 Hz), 99.5 (Q p-cymene \u2212CCH(CH3)2), 97.9 (Q p-cymene \u2212C(CH2)), 93.6 (methine\u2212COCHCO\u2212), 84.6 (p-cymene Ar\u2013CH), 84.5 (p-cymene Ar\u2013CH), 81.8 (Q Cp \u2212CC4H5), 80.0 (p-cymene Ar\u2013CH), 80.0 (p-cymene Ar\u2013CH), 71.9 (Cp \u2212CC4H4), 71.8 (Cp \u2212CC4H4), 71.0 (Cp \u2212C5H5), 70.0 (Cp \u2212CC4H4), 68.9 (Cp \u2212CC4H4), 31.7 (p-cymene \u2212CCH(CH3)2), 22.7 (p-cymene CCH(CH3)2), 22.6 (p-cymene \u2212CCH(CH3)2), 17.9 (p-cymene \u2212C(CH3)). Analysiscalculated for C29H28ClFFeO2Ru::C 56.19, H 4.55, Cl 5.72%. Found: C 56.30, H 4.85, Cl 5.30%. HR-MS[ES+] calculated for C29H28ClFFeO2Ru: 620.016. Found: 585.048 [MH+]-Cl.Yield: 0.19 g, 78%. 1H NMR 2CO, \u03b4); 7.45  = 6.9 Hz, ortho ArC\u2013H), 6.99  = 8.9 Hz, 4J(1H\u20131H) = 2.1 Hz, para ArC\u2013H), 6.05 ,5.60  = 6.0 Hz, p-cymene ArC\u2013H), 5.28  = 5.0 Hz, p-cymeneArC\u2013H), 4.87 , 4.83 , 4.36, 4.32 , 4.12 , 2.90  = 7.0 Hz, p-cymene\u2212CCH(CH3)2), 2.17), 1.34  = 6.9 Hz, p-cymene \u2212CCH(CH3)2). 13C{1H} NMR 2CO, \u03b4); 188.4 (Q C\u2013O), 174.6 (Q C\u2013O),163.7  = 264.0 Hz, 3J(13C\u201319F) = 12.8 Hz), 144.3  = 8.3 Hz), 110.7  = 20.2, 6.2 Hz), 105.9  = 26.0 Hz), 99.6 2), 98.0 (Q p-cymene \u2212C(CH3)), 93.7 (methine\u2212COCHCO\u2212), 84.6 (p-cymene Ar\u2013CH), 84.5 (p-cymene Ar\u2013CH), 81.6 (Q Cp \u2212CC4H4), 80.0 (p-cymene Ar\u2013CH), 72.1 (Cp \u2212CC4H4), 72.0 (Cp \u2212CC4H4), 71.0 (Cp \u2212C5H5), 70.0 (Cp \u2212CC4H4), 69.1 (Cp \u2212CC4H4), 31.7 (p-cymene \u2212CCH(CH3)2), 22.7 (p-cymene \u2212CCH(CH3)2), 22.6 (p-cymene \u2212CCH(CH3)2), 17.9 (p-cymene \u2212C(CH3)). Analysiscalculated for C29H27ClF2FeO2Ru: C 54.60, H 4.27, Cl 5.56%. Found: C 55.20, H 4.40, Cl5.57%. HR-MS [ES+] calculated for C29H27ClF2FeO2Ru: 638.006. Found: 603.040 [MH+]-Cl.Yield: 0.19 g, 76%. 1H NMR 2CO, \u03b4); 7.91  = 5.5, 3J(1H\u201319F) = 3.2 Hz, meta ArC\u2013H), 7.04  = 8.7 Hz, meta ArC\u2013H), 6.02 , 5.56  = 6.4 Hz, p-cymene ArC\u2013H), 5.24  = 4.4 Hz, p-cymeneArC\u2013H), 4.83  = 1.2 Hz, Cp \u2212CC4H4), 4.73  = 1.2 Hz,Cp \u2212CC4H4), 4.32 = 2.4, 1.1 Hz, Cp \u2212CC4H4), 4.28  = 2.4, 1.1 Hz, Cp \u2212CC4H4), 4.11 , 2.90  = 6.9Hz, p-cymene \u2212CCH(CH3)2, H8), 2.16 ), 1.33  = 6.9 Hz, p-cymene \u2212CCH(CH3)2); 13C{1H} NMR 2CO, \u03b4); 187.0 (Q C\u2013O), 177.0 (Q C\u2013O),165.0  = 248.6 Hz), 136.9  = 3.1 Hz),130.3  =8.8 Hz), 115.6  = 21.8 Hz), 99.5 (Q p-cymene \u2212CCH(CH3)2), 97.8 (Q p-cymene \u2212C(CH3)), 93.2 (methine\u2212COCHCO\u2212), 84.6 (p-cymene Ar\u2013CH), 84.5 (p-cymene Ar\u2013CH), 82.0 (Q Cp \u2212CC4H4), 80.0 (p-cymene Ar\u2013CH), 71.7 (Cp \u2212CC4H4), 71.7 (Cp \u2212CC4H4), 70.9 (Cp \u2212C5H5), 69.9 (Cp \u2212CC4H4), 68.8 (Cp \u2212CC4H4), 31.7 (p-cymene \u2212CCH(CH3)2), 22.7 (p-cymene \u2212CCH(CH3)2), 22.6 (p-cymene \u2212CCH(CH3)2), 17.9 (p-cymene \u2212C(CH3)). Analysiscalculated for C29H28ClFFeO2Ru: C56.19, H 4.55, Cl 5.72%. Found: C 56.20, H 4.95, Cl 5.95%. HR-MS [ES+] calculated for C29H28ClFFeO2Ru: 620.016. Found: 585.047 [MH+]-Cl.Yield: 0.12 g, 82%. 1H NMR 2CO, \u03b4); 7.99  = 1.8 Hz, ortho ArC\u2013H), 7.93  = 7.8 Hz, 4J(1H\u20131H) = 1.4 Hz, ortho ArC\u2013H), 7.52  = 8.0 Hz, 4J(1H\u20131H) = 1.1 Hz, para ArC\u2013H), 7.46  = 7.8 Hz, meta ArC\u2013H), 6.20 , 5.73  = 4.8 Hz, 4J(1H\u20131H) = 1.4 Hz, p-cymene ArC-H), 5.42  = 5.0 Hz, p-cymene ArC\u2013H), 5.01  = 1.3 Hz, Cp \u2212CC4H4), 4.93  = 1.3 Hz,Cp \u2212CC4H4), 4.49, 4.45 , 4.27 , 3.06  = 6.9 Hz, p-cymene\u2212CCH(CH3)2), 2.32), 1.50  = 7.1 Hz, p-cymene\u2212CCH(CH3)2); 13C{1H} NMR 2CO, \u03b4); 187.7 (Q C\u2013O), 176.3(Q C\u2013O), 142.6 (meta Ar\u2013CCl), 134.6 (Q Ar\u2013C), 130.9 (ortho Ar\u2013CH), 130.7 (ortho Ar\u2013CH), 127.8 (para Ar\u2013CH), 126.2 (meta Ar\u2013CH), 99.5 (Q p-cymene \u2212CCH(CH3)2), 97.6 (Q p-cymene \u2212C(CH3)), 93.6 (methine\u2212COCHCO\u2212), 84.6 (p-cymene Ar\u2013CH), 84.5 (p-cymene Ar\u2013CH), 81.8 (Q Cp \u2212CC4H4), 80.0 (p-cymene Ar\u2013CH), 80.0 (p-cymene Ar\u2013CH), 71.9 (Cp \u2212CC4H4), 71.9 (Cp \u2212CC4H4), 71.0 (Cp \u2212C5H5), 70.0 (Cp \u2212CC4H4), 68.9 (Cp \u2212CC4H4), 31.7 (p-cymene \u2212CCH(CH3)2), 22.7 (p-cymene \u2212CCH(CH3)2), 22.6 (p-cymene \u2212CCH(CH3)2), 17.9 (p-cymene \u2212C(CH3)). Analysis calculated for C29H28Cl2FeO2Ru: C 54.74, H 4.44, Cl11.14%. Found: C 53.95, H 4.51, Cl 11.06%. HR-MS [ES+]calculated for C29H28Cl2FeO2Ru: 635.986. Found: 601.018 [MH+]-Cl.Yield: 0.23 g, 92%. 1H NMR 2CO, \u03b4); 7.94  = 1.8 Hz, ortho ArC\u2013H), 7.59  = 1.8 Hz, para ArC\u2013H), 6.21 ,5.75  = 5.7 Hz, p-cymene ArC\u2013H), 5.44  = 5.7 Hz, p-cymeneArC\u2013H), 5.03  = 0.9 Hz, Cp \u2212CC4H4), 4.98  = 1.1 Hz,Cp \u2212CC4H4), 4.52, 4.47 , 4.27 , 3.05 2), 2.32 ), 1.49  = 7.1 Hz, p-cymene \u2212CCH(CH3)2); 13C{1H} NMR 2CO, \u03b4); 187.7 (Q C\u2013O),17.5 (Q C\u2013O), 143.0 (Q meta Ar\u2013CCl), 134.6 (Q Ar\u2013C), 129.4 (ortho Ar\u2013CH), 125.5 (para Ar\u2013CH), 98.7 (Q p-cymene \u2212CCH(CH3)2), 97.0 (Q p-cymene \u2212C(CH)3), 92.9 (methine\u2212COCHCO\u2212), 83.7 (p-cymene Ar\u2013CH), 83.6 (p-cymene Ar\u2013CH), 80.6 (Q Cp \u2212CC4H4), 79.2 (p-cymene Ar\u2013CH), 79.1 (p-cymene Ar\u2013CH), 71.3 (Cp \u2212CC4H4), 71.2 (Cp \u2212CC4H4), 70.1 (Cp \u2212C5H5), 69.2 (Cp \u2212CC4H4), 68.2 (Cp \u2212CC4H4), 30.9 (p-cymene \u2212CCH(CH3)2), 21.8 (p-cymene \u2212CCH(CH3)2), 21.7 (p-cymene \u2212CCH(CH3)2), 17.0 (p-cymene \u2212C(CH3)). Analysiscalculated for C29H27Cl3FeO2Ru\u00b7H2O: C 50.57, H 4.24, Cl 15.44%. Found: C 51.00,H 3.90, Cl 15.89%. HR-MS [ES+] calculated for C29H27Cl3FeO2Ru: 669.947. Found: 634.979[M+]-Cl.Yield: 0.16 g, 61%. 1H NMR 2CO, \u03b4); 7.86  = 8.7 Hz, ortho ArC\u2013H), 7.31  = 8.7 Hz, meta ArC\u2013H), 6.03 ,5.56  = 6.0 Hz, p-cymene ArC\u2013H), 5.24  = 4.6 Hz, p-cymeneArC\u2013H), 4.84  = 1.4 Hz, Cp \u2212CC4H4), 4.74  = 1.2 Hz,Cp \u2212CC4H4), 4.33 = 2.3, 1.2 Hz, Cp \u2212CC4H4), 4.29  = 2.3, 1.4 Hz, Cp \u2212CC4H4), 4.11 , 2.90  = 6.9 Hz,\u2212CCH(CH3)2), 2.16), 1.33  = 6.9 Hz, p-cymene\u2212CCH(CH3)2); 13C{1H} NMR 2CO, \u03b4); 187.3 (Q C\u2013O), 176.8(Q C\u2013O), 139.2 (Q Ar\u2013C), 136.6 (Q para Ar\u2013C), 129.6 (ortho Ar\u2013CH), 129.0 (meta Ar\u2013CH), 99.5 (Q p-cymene \u2212CCH(CH3)2), 97.8 (Q p-cymene \u2212C(CH3)), 93.4 (methine\u2212COCHCO\u2212), 84.6 (p-cymene Ar\u2013CH), 84.5 (p-cymene Ar\u2013CH), 81.9 (Q Cp \u2212CC4H4), 80.0 (p-cymene Ar\u2013CH), 71.9 (Cp \u2212CC4H4), 71.8 (Cp \u2212CC4H4), 71.0 (Cp \u2212C5H5), 70.0 (Cp \u2212CC4H4), 68.8 (Cp \u2212CC4H4), 31.74 (p-cymene \u2212CCH(CH3)2), 22.7 (p-cymene \u2212CCH(CH3)2), 22.6 (p-cymene \u2212CCH(CH3)2), 17.9 (p-cymene \u2212C(CH3)). Analysiscalculated for C29H28Cl2FeO2Ru: C 54.74, H 4.44, Cl 11.14%. Found: C 54.90, H 4.50, Cl 11.10%.HR-MS [ES+] calculated for C29H28Cl2FeO2Ru: 635.986. Found: 601.016 [MH+]-Cl.Yield: 0.23 g, 91%. 1H NMR 2CO, \u03b4); 7.99  = 1.7 Hz, ortho ArC\u2013H), 7.81  = 7.8 Hz, 4J(1H\u20131H) = 1.1 Hz, ortho ArC\u2013H), 7.51  = 7.8 Hz, 4J(1H\u20131H) = 0.9 Hz, para ArC\u2013H), 7.24  = 7.8 Hz, meta ArC\u2013H), 6.03 , 5.57  = 5.0 Hz, 4J(1H\u20131H) = 1.4 Hz, p-cymene ArC\u2013H), 5.26  = 5.0 Hz, p-cymeneArC\u2013H), 4.85  = 1.2 Hz,Cp \u2212CC4H4), 4.77 = 1.2 Hz, Cp \u2212CC4H4), 4.34 , 4.30 , 4.11 , 2.90  = 6.9 Hz, p-cymene\u2212CCH(CH3)2), 2.16), 1.33  = 7.1 Hz, p-cymene\u2212CCH(CH3)2); 13C{1H} 2CO,\u03b4); 187.7 (Q C\u2013O), 176.2 (Q C\u2013O), 142.8 (Q meta Ar\u2013C), 133.8 (ortho Ar\u2013CH), 130.9 (ortho Ar\u2013CH), 130.8 (meta Ar\u2013CH), 126.6 (para Ar\u2013CH), 122.8 (meta Ar\u2013CBr), 99.5 (Q p-cymene \u2212CCH(CH3)2), 97.9 (Q p-cymene\u2212C(CH3)), 93.6 (methine \u2212COCHCO\u2212), 84.6 (p-cymene Ar\u2013CH), 84.5 (p-cymene Ar\u2013CH), 81.7 (Q Cp \u2212CC4H4), 80.1 (p-cymene Ar\u2013CH), 80.0 (p-cymene Ar\u2013CH), 72.0 (Cp \u2212CC4H4), 71.9 (Cp \u2212CC4H4), 71.0 (Cp \u2212C5H5), 70.0 (Cp \u2212CC4H4), 68.9 (Cp \u2212CC4H4), 31.7 (p-cymene \u2212CCH(CH3)2), 22.7 (p-cymene \u2212CCH(CH3)2), 22.6 (p-cymene \u2212CCH(CH3)2), 17.9 (p-cymene \u2212C(CH3)). Analysis calculated for C29H28BrClFeO2Ru: C 51.16, H 4.15%. Found: C 51.06,H 4.18%. HR-MS [ES+] calculated for C29H28BrClFeO2Ru: 679.935. Found: 646.967 [MH+]-Cl.Yield: 0.23 g, 84%. 1H NMR 2CO, \u03b4); 7.78  = 8.7 Hz, ortho ArC\u2013H), 7.46  = 8.7 Hz, meta ArC\u2013H), 6.03 ,5.56  = 6.2 Hz, p-cymene ArC\u2013H), 5.24  = 4.7 Hz, p-cymeneArC\u2013H), 4.83  = 1.3 Hz, Cp \u2212CC4H4), 7.47  = 1.3 Hz,Cp \u2212CC4H4), 4.33, 4.29 , 4.11 , 2.90  = 6.9 Hz, p-cymene\u2212CCH(CH3)2), 2.16), 1.33  = 6.9 Hz, p-cymene\u2212CCH(CH3)2). 13C{1H} NMR 2CO, \u03b4); 194.4 (Q C\u2013O), 189.7(Q C\u2013O), 139.7 (Q Ar\u2013C), 132.0 (ortho Ar\u2013CH), 129.8 (meta Ar\u2013CH), 106.7 (para Ar\u2013CBr), 99.5 (Q p-cymene \u2212CCH(CH3)2), 97.8 (Q p-cymene \u2212C(CH3)), 93.4 (methine\u2212COCHCO), 84.6 (p-cymeneAr\u2013CH), 84.5 (p-cymeneAr\u2013CH), 81.9 (Q Cp \u2212CC4H4), 80.0 (p-cymene Ar\u2013CH), 80.0 (p-cymene Ar\u2013CH), 71.9 (Cp \u2212CC4H4), 71.8 (Cp \u2212CC4H4), 71.0 (Cp \u2212C5H5), 69.9 (Cp \u2212CC4H48), 68.8 (Cp \u2212CC4H4), 31.7 (p-cymene \u2212CCH(CH3)2), 22.7 (p-cymene \u2212CCH(CH3)2), 22.6 (p-cymene \u2212CCH(CH3)2), 17.9 (p-cymene \u2212C(CH3)). Analysiscalculated for C29H28BrClFeO2Ru:C 51.16, H 4.15%. Found: C 51.20, H 4.20%. HR-MS [ES+]calculated for C29H28BrClFeO2Ru:679.935. Found: 644.968 [M+]-Cl.Yield: 0.17 g, 64%. 1H NMR 2CO, \u03b4); 8.20  = 1.6 Hz, ortho ArC\u2013H), 7.83  = 8.0 Hz, 4J(1H\u20131H) = 1.2 Hz, ortho ArC\u2013H), 7.71  = 7.8 Hz, 4J(1H\u20131H) = 0.7 Hz, para ArC\u2013H), 7.10  = 7.8 Hz, meta ArC\u2013H), 6.01 , 5.57  = 4.81, 4J(1H\u20131H) = 1.3 Hz, p-cymene ArC\u2013H), 5.26  = 5.0 Hz, p-cymeneArC\u2013H), 4.85  = 1.2 Hz, Cp \u2212CC4H4), 4.76  = 1.2 Hz,Cp \u2212CC4H4), 4.34, 4.30 , 4.11 , 2.90  = 6.9 Hz, p-cymene\u2212CCH(CH3)2), 2.16), 1.34  = 7.1 Hz, p-cymene\u2212CCH(CH3)2); 13C{1H} NMR 2CO, \u03b4); 187.6 (Q C\u2013O), 176.3(Q C\u2013O), 142.7 (Q Ar\u2013C), 139.9 (ortho Ar\u2013CH), 136.9 (ortho Ar\u2013CH), 131.0 (meta Ar\u2013CH), 127.0 (para Ar\u2013CH), 105.9 (ortho Ar\u2013CCI), 99.5 (Q p-cymene \u2212CCH(CH3)2), 97.8 (Q p-cymene \u2212C(CH3)2), 93.5 (methine \u2212COCHCO\u2212),84.5 (p-cymene Ar\u2013CH), 84.5 (p-cymene Ar\u2013CH), 81.8 (Q \u2212CC4H4), 80.1 (p-cymene Ar\u2013CH), 80.0 (p-cymene Ar\u2013CH), 71.9 (Cp \u2212CC4H4), 71.9 (Cp \u2212CC4H4), 71.0 (Cp \u2212C5H5), 70.0 (Cp \u2212CC4H4), 68.9 (Cp \u2212CC4H4), 31.7 (p-cymene \u2212CCH(CH3)2), 22.7 (p-cymene -CCH(CH3)2), 22.6 (p-cymene \u2212CCH(CH3)2), 17.8 (p-cymene \u2212C(CH3)). Analysis calculated for C29H28ClFeIO2Ru: C 47.86, H 3.88%. Found: C 47.89, H 3.72%.HR-MS [ES+] calculated for C29H28ClFeIO2Ru: 727.922. Found: 692.954 [M+]-Cl.Yield: 0.23 g, 80%; 1H NMR 2CO, \u03b4); 7.66  = 12.8 Hz, ortho and meta ArC\u2013H), 6.02 , 5.56 , 5.24 , 4.83 , 4.73 , 4.31  = 18.6 Hz,Cp \u2212CC4H4), 4.11, 2.90  = 6.8 Hz, p-cymene \u2212CCH(CH3)2), 2.15 ), 1.34  = 6.2 Hz, p-cymene \u2212CCH(CH3)2); 13C{1H} 2CO, \u03b4); 187.1 (Q C\u2013O), 178.8 (Q C\u2013O),140.2 (Q Ar\u2013C), 138.2 (ortho Ar\u2013CH), 129.8 (meta Ar\u2013CH), 105.9 (para Ar\u2013CI), 99.5 (Q p-cymene \u2212CCH(CH3)2), 97.8 (Q p-cymene \u2212C(CH3)), 93.3 (methine \u2212COCHCO\u2212), 84.6 (p-cymene Ar\u2013CH), 84.5 (p-cymene Ar\u2013CH), 81.9 (Q Cp \u2212CC4H4), 80.0 (p-cymene Ar\u2013CH), 80.0 (p-cymene Ar\u2013CH), 71.9 (Cp \u2212CC4H4), 71.8 (Cp \u2212CC4H4), 71.0 (Cp \u2212C5H5), 69.9 (Cp \u2212CC4H4), 68.8 (Cp \u2212CC4H4), 31.7 (p-cymene \u2212CCH(CH3)2), 22.7 (p-cymene \u2212CCH(CH3)2), 22.6 (p-cymene \u2212CCH(CH3)2), 17.9 (p-cymene \u2212C(CH3)). Analysis calculated for C29H28ClFeIO2Ru: C 47.86, H 3.88%. Found: C 48.00,H 3.90%. HR-MS [ES+] calculated for C29H28ClFeIO2Ru: 727.922. Found: 692.955 [M+]-Cl.Yield: 0.29 g, 79%."}
{"text": "In the original publication , there wn = 176) as published. During figure editing, the labels for premenopausal and postmenopausal women were accidentally switched. The first group should be postmenopausal and the second group should be premenopausal.In the original publication , there wAn error in the mean values and SD of free 25(OH)D was also noticed. Due to mistakenly placed decimal points, the values and SD presented in the graph were higher . Additionally, there was a mistake in the caption of Figure 3. The figure presents differences between total, free, and bioavailable 25(OH)D concentrations. However, in the published version, only total 25(OH)D concentrations are mentioned. For better clarity, the caption has been corrected to include the missing information.The corrected n = 176). Mean values and SD of free 25(OH)D were presented with wrong decimal point. The corrected In the original publication , there wThe authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "Biol. Open (2017) 6, 1123-1129 (doi:10.1242/bio.025767).There are potential issues in Figs 2 and 5 in It appears that there may be duplication of the GAPDH blots in Figs 2C and 5A and the \u03b2-actin blots in Figs 2D and Fig 5C.We have made multiple attempts to contact all authors to request original data for the affected figures but have not received a response. Therefore, the journal is publishing this note to alert readers to our concerns."}
{"text": "After having been in contact with the authors, they accepted the decision to retract the paper. The Editor apologizes to the readership for any inconvenience caused.Owing to the fact that some of the data in the above article were already under consideration for publication prior to its submission to"}
{"text": "After having consulted the authors in this regard, they agreed with the decision to retract this paper. The Editor deeply regrets any inconvenience that has been caused to the readership of the Journal.After having conducted an independent investigation in the Editorial Office, the Editor of"}
{"text": "In the original publication , there wThe authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated with the correct"}
{"text": "The authors wish to make the following changes to their paper . In the The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. This correction was approved by the academic editor. The original publication has also been updated."}
{"text": "Non-coding RNA are a class of RNA that lack the potential to encode proteins. CircRNAs, generated by a post-splicing mechanism, are a newly discovered type of non-coding RNA with multi-functional covalent loop structures. CircRNAs may play an important role in the occurrence and progression of tumors. Research has shown that circRNAs are aberrantly expressed in various types of human cancers, including leukemia. In this review, we summarize the expression and function of circRNAs and their impact on different types of leukemia. We also illustrate the function of circRNAs on immune modulation and chemoresistance in leukemia and their impact on its diagnosis and prognosis. Herein, we provide an understanding of recent advances in research that highlight the importance of circRNAs in proliferation, apoptosis, migration, and autophagy in different types of leukemia. Furthermore, circRNAs make an indispensable difference in the modulation of the immunity and chemoresistance of leukemia. Increasing evidence suggests that circRNAs may play a vital role in the diagnostic and prognostic markers of leukemia because of their prominent properties. More detailed preclinical studies on circRNAs are needed to explore effective ways in which they can serve as biomarkers for the diagnosis and prognosis of leukemia in vivo. Leukemia is a type of blood cancer derived from hematopoietic stem and progenitor cells . These cCircular RNAs (circRNAs) are an abundant class of endogenous noncoding RNAs (ncRNAs) that are characterized by covalently closed loop structures with no exposed 3\u2032\u00a0 and 5\u2032\u00a0 ends . This stThe current research on circRNAs in leukemia is not comprehensive. Here, we briefly review the impact of the expression and function of circRNAs on different human leukemias, focusing on the role of circRNAs in leukemia immunomodulation and chemoresistance, as well as the potential of circRNAs in leukemia diagnosis and prognosis. This review help researchers to quickly understand the recent research progress of circRNAs in human leukemia and provide valuable information for future research directions.CircRNAs are non-coding RNA with multiple functions that have a covalent-loop structure. Leukemia is a blood cancer derived from hematopoietic stem and progenitor cells. The current research on circRNAs in leukemia is not comprehensive. Therefore, we briefly reviewed the impact of the expression and function of circRNAs on different human leukemias, focusing on the role of circRNAs in leukemia immunomodulation and chemoresistance. We also focused on the potential of circRNAs in the diagnosis and prognosis of the disease as well as some issues faced by circRNAs in human leukemia. The preclinical studies of circRNAs need to be further developed to explore their use as diagnostic and prognostic biomarkers in leukemia in vivo. In summary, this review is meant to help researchers quickly understand the recent research progress concerning the role of circRNAs in human leukemia and to provide valuable information for future research directions.To ensure an inclusive and unbiased analysis of the literature and to accomplish the review objectives, we searched the following literature databases: PubMed, Google Scholar and Web of Science. The search terms included: circRNA, leukemia, chemoresistance, immune modulation, and biomarker. It is worth noting that the keywords used and their variants and related words can be sorted, combined, and then searched.1. The terms searched for circRNA were: circRNA, circular RNA, noncoding RNA, circular intronic RNA, exon-intron circRNA, epigenetic, epigenetic regulation.2. The terms searched for leukemia were: leukemia, acute myeloid leukemia, acute myeloid leukemia, chronic myeloid leukemia, chronic lymphocytic leukemia, AML, ALL, CML, CLL.3. The terms searched for circRNA and leukemia were: chemoresistance, immune modulation, biomarker.This article is based on published literature. The aspects of the inclusion criteria are the retrieval keywords, information not covered by previous literature, and most importantly, the use of a clear and credible source.Acute myelogenous leukemia (AML) is a highly aggressive malignancy of hematopoietic stem cells. A series of studies have shown that circRNAs are aberrantly expressed in AML . Sun et in vitro and in vivo (Acute lymphoblastic leukemia (ALL) is a common type of malignancy that occurs in children. Growing evidence indicates that circRNAs may act as an oncogene, playing an important role in the development of ALL. It was reported that circPVT1 was significantly highly expressed in ALL patients, and knocking out circPVT1 could provoke apoptosis and suppresses the proliferation of ALL cells . Similar in vivo . TherefoChronic myelogenous leukemia (CML) is a myeloproliferative disease that originates primarily from hematopoietic stem cells. Studies have shown that a variety of circRNAs are aberrantly expressed in CML. via the circ_0132266/miR-337-3p/PML axis, demonstrating that circ_0132266 was crucial for the malignant proliferation of CLL (Wu 2019). Circ-RPL15, a circRNA aberrantly expressed in CLL patients, was found to regulate the RAS/RAF1/MEK/ERK signaling pathway by binding to miR-146b-3p, affecting CLL progression  is a clonal disease of mature B cells. Existing research has found that some circRNAs are expressed abnormally in CLL. gression . Xia et t of CLL . A mitoct of CLL .etc., have obvious curative effects in the early stages of administration. Over time, however, the efficacy of these drugs declines significantly, and leukemia patients may develop resistance to these drugs. Growing evidence has suggested that circRNAs significantly impact the chemoresistance of leukemia patients (via the miR-345-5p/FZD5 axis, indicating that circNPM1 was a potential marker in AML drug resistance therapy. circPAN3 was found to be abnormally highly expressed in doxorubicin-resistant AML cells, indicating that circPAN3 may promote AML resistance to doxorubicin by regulating cellular autophagy and affecting apoptosis-related proteins expression through the AMPK/mTOR signaling pathway (As with many other cancers, drug resistance in leukemia patients is a difficult issue to address. Commonly used drugs for the treatment of leukemia, such as rituximab, chlorambucil, bendamustine, patients . Cao et patients . Ding et pathway . In addi pathway . Ping et pathway . The aboImmune regulation means that the various immune cells and immune molecules of the body maintain their own physiologically dynamic balance and relative stability by promoting and restricting each other. Depending on the type of immune cells, the immune system can induce a series of responses to fight viruses, bacteria, and tumors. It is worth noting that circRNAs can be involved in some regulatory responses of the immune system. Recently, a number of circRNAs have been found to be aberrantly expressed in leukemia. A growing body of evidence points the use of circRNAs as effective biomarkers for the diagnosis and prognosis of leukemia due to their unique properties . For exaAt present, chemotherapy remains one of the most effective methods of treatment for leukemia. With the rapid development of technology, circRNAs have opened up a new research field as a novel type of non-coding RNA. Increasing evidence suggests that circRNAs can broadly regulate human physiological and pathological processes, especially in leukemia. In this review, we provided an overview of the latest research advances in circRNAs and highlighted the role they play in leukemia.in vitro experiments such as cells and tissues, and has not been applied to the clinical setting. Therefore, we need to increase our preclinical investment to explore effective methods of applying circRNAs as biomarkers for the diagnosis and prognosis in leukemia in vivo. First, more in vitro experiments should be conducted to screen for efficient and expected circRNAs. Second, a robust circRNA database should be established, especially those with tissue specificity. Third, novel tools and methods should be developed to improve the specificity of circRNA detection. In conclusion, circRNAs are a class of regulatory factors that can play an important role in leukemia, and they can regulate the occurrence and development of leukemia. Therefore, it is necessary to strengthen the research on circRNAs in the future so that the results can be transferred from in vitro research to in vivo research. These applications will better serve those affected by leukemia and will allow for the development of precision medicine in the near future.Increasing amounts of research have shown that circRNAs are aberrantly expressed in leukemia . CircRNA"}
{"text": "In"}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.The Editorial Office have conducted an independent assessment of these data, and can confirm the veracity of the concerns that were raised by the reader; therefore, the Editor of"}
{"text": "Following publication, concerns were raised regarding the contributions of the authors of the article.Our investigation, conducted in accordance with Frontiers policies, confirmed a serious breach of our authorship policies and of publication ethics; the article is therefore retracted.The authors do not agree to this retraction.This retraction was approved by the Chief Editors of Frontiers in Bioengineering and Biotechnology and the Chief Executive Editor of Frontiers."}
{"text": "Correction to: Pediatric Radiology (2023)https://doi.org/10.1007/s00247-023-05618-5The initial online version states that all authors participated in the roundtable discussion.Correction:Only the following authors participated in the roundtable discussion.Chair: A.C.O.Panel/speakers: A.M.J., K.M., I.M., M.R.The original article has been corrected."}
{"text": "There was an unclear passage in the original publication . The valSection 3, Results\u201d:A correction has been made to \u201c\u03c4 = 4.02 \u00d7 10\u22127 J/m. Furthermore, for better display of the validity of the measurement results, C\u03b8 versus one divided by the radius of the spheres was plotted too . The solid red line corresponds to the previously determined \u03c4. The two additional dotted lines correspond to 2 \u03c4 and 1/2 \u03c4. Thus, more than 90% of the data points are located in the funnel that spans between \u22128.04 \u00d7 10\u22127 J/m < \u03c4 < \u22122.01 \u00d7 10\u22127 J/m.\u201d\u201cFrom this fit, we determined an absolute value for the apparent line tension, In the original publication, Ref. [22] was not cited correctly, it should change as follows:Phys. Rev. Lett.2019, 123, 94501New Ref. 22: Zhao, B.; Luo, S.; Bonaccurso, E.; Auernhammer, G.K.; Deng, X.; Li, Z.; Chen, L. Resolving the Apparent Line Tension of Sessile Droplets and Understanding its Sign Change at a Critical Wetting Angle. The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "Following the publication of this article , concernLanes 2\u20134 of the Fig 5C Atg5 panel and the Fig 8C Akt panel.Lanes 2\u20135 of the Fig 3A p62 panel of this study  and the The Fig 3D Tubulin panel of this study  and the The Fig5C Akt panel of this study  and laneLanes 1\u20132 of the Fig 5C Akt panel of this study .The Fig 7C Akt panel of this study  and the The Fig 8C p62 panel of this study  and laneLanes 1\u20134 of the Fig S3A AMPK panel of this study .Lanes 2\u20135 of the Fig S3A AMPK panel of this study  and the The corresponding author commented that some western blot images were misused in this article  and requPLOS ONE Editors retract this article.In light of the concerns affecting multiple figure panels that question the integrity of these data, the CW agreed with the retraction. FG, YD, YZhang, YZhou, and ML either did not respond directly or could not be reached."}
{"text": "In \u201cPsychiatric Treatment Conducted via Telemedicine Versus In-Person Modality in Posttraumatic Stress Disorder, Mood Disorders, and Anxiety Disorders: Systematic Review and Meta-Analysis\u201d , the authors noted one error.In The correction will appear in the online version of the paper on the JMIR Publications website on September 18, 2023 together with the publication of this correction notice. Because this was made after submission to PubMed, PubMed Central, and other full-text repositories, the corrected article has also been resubmitted to those repositories."}
{"text": "In the original publication , there wThe authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updadated."}
{"text": "RSC Advances is publishing this expression of concern in order to alert our readers that we are presently unsure of the reliability of the data reported in Fig. 2 of the article. Fig. 2a and b are identical. The authors have requested Fig. 2b be removed from the article but are unable to provide a replacement for Fig. 2b. An independent expert has stated it would not be appropriate to remove Fig. 2b completely and requested the authors reproduce their results.An expression of concern will continue to be associated with the article until we receive conclusive evidence regarding the reliability of the reported data.Laura Fisher9th March 2023RSC AdvancesExecutive editor,"}
{"text": "Cell Discovery (2021) 7:59Correction to: 10.1038/s41421-021-00285-y published online 03 August 2021The authors apologize for an error in Fig."}
{"text": "This paper  presentsHowever, the topic of cybersecurity and privacy will never be outdated since the evolution of COVID-19. The authors must work a lot more to identify the knowledge gap in the existing literature first and then propose novel viewpoints to bridge the gaps. Before drawing a conclusion, the authors must add a discussion on how their findings compare to other studies (references) that were published very recently.Appropriate references to related work are not covered sufficiently in the list, especially for the contact tracing section. A systematic review of the global deployment status of contact tracing apps is recommended, as in .In addition to the majority of qualitative descriptions, quantitative statistics are suggested to complement and support the statements in the manuscript.After the first round of review, the reviewer appreciates the revision effort the authors have made in improving the manuscript.However, the authors may need to redefine the contribution and the title in a more specific and unique manner.The current title looks quite broad and not new, as a number of similar articles have been disseminated on the web eg, ,4)..4]).The authors might consider reducing the overlap with published work as illustrated above."}
{"text": "In the original published version of this article, the typesetters have used the outdated version, the authors reviewed the proof and approved it before publication. An outdated version of the paper was published. We will publish a final version that the authors and editors approved. The correct version of the manuscript will replace the outdated version. The authors apologize for the errors. Both the HTML and PDF versions of the article have been updated to correct the errors.The authors declare no conflict of interest."}
{"text": "JCI Insight. 2020;5(9):e132747. https://doi.org/10.1172/jci.insight.132747Original citation: JCI Insight. 2023;8(6):e169756. https://doi.org/10.1172/jci.insight.169756Citation for this corrigendum: 2+ chelator, but instead reduces Fe2+ via conversion to Fe3+. As MFG mediates reduction of Fe2+ and suppresses ferroptosis, the overall conclusions are not affected. For clarity, the authors have removed references to MFG-mediated chelation throughout, updated the Graphical Abstract, and renumbered the reference list to refer to Hirayama et al. .The authors recently became aware that the Mito-FerroGreen (MFG) used in this study is not an Fea et al.  when firThe authors regret the errors."}
{"text": "In the original publication . In FiguThe authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "After having been in contact with the authors, they accepted the decision to retract the paper. The Editor apologizes to the readership for any inconvenience caused.Owing to the large number of overlapping data panels identified in comparing Figs. 2A and 6A, and the fact that the contentious data in Figs. 2C and 6C of the above article had already been published prior to its submission to"}
{"text": "Correction: Journal of Translational Medicine (2023) 21:157 10.1186/s12967-023-04011-yFollowing publication of the original article , we haveAcknowledgementsThe authors thank Alexey Zakharov, Jorge Neyra and Dac-Trung Nguyen for their thoughtful feedback and technical implementation as well as Richard Pacheco, Eduardo Luiggi, Carlin Biyoo, Ke Wang and Hugo Hernandez for infrastructure support."}
{"text": "In \u201cDigital Phenotyping for Differential Diagnosis of Major Depressive Episode: Narrative Review\u201d  the authors made three additions to the authorship list.The authorship is currently listed as:Eric Ettore, Philipp M\u00fcller, Jonas Hinze, Michel Benoit, Bruno Giordana, Danilo Postin, Amandine Lecomte, Hali Lindsay, Philippe Robert, Alexandra K\u00f6nigAnd will be changed to read as follows:Eric Ettore, Philipp M\u00fcller, Jonas Hinze, Matthias Riemenschneider, Michel Benoit, Bruno Giordana, Danilo Postin, Rene Hurlemann, Amandine Lecomte, Michel Musiol, Hali Lindsay, Philippe Robert, Alexandra K\u00f6nigThe authors who have been recently added are affiliated with the following institutions, which are already correctly presented in the affiliation list:3:Matthias RiemenschneiderDepartment of Psychiatry and Psychotherapy, Saarland University Medical Center, Hombourg, Germany.5:Rene HurlemannDepartment of Psychiatry, School of Medicine and Health Sciences, Carl von Ossietzky University of Oldenburg, Bad Zwischenahn, Germany.6:Michel MusiolResearch Department S\u00e9magramme Team, Institut national de recherche en informatique et en automatique, Nancy, France.The correction will appear in the online version of the paper on the JMIR Publications website on April 12, 2023, together with the publication of this correction notice. Because this was made after submission to PubMed, PubMed Central, and other full-text repositories, the corrected article has also been resubmitted to those repositories."}
{"text": "In the original publication , there wTo the correct version appears below. The marker labels of DNA ladder in Figures 1\u20136 should be the same as those in the corrected In the original publication , there w\u201cLP (backward loop primer)\u201d in the fourth line of The corrected content appears below.There was an error in the original publication . \u201cLF, anA correction has been made to Section 2.2. LAMP Reaction on page 2: T. tenax (GenBank Accession No. U86615) were designed using the software Primer explorer V.5 (http://primerexplorer.jp (accessed on 28 February 2020). These include FIP and BIP, F3 and B3, LF, and LB  was carried out on the closely related protozoan T. vaginalis, to check for specificity.The LAMP primers targeting the ITS and 5.8S rRNA gene of , and LB . MultiplThe authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "NH2-UIO-66 (Zr), with a maximum emission wavelength of 455 nm under 350 nm excitation, was prepared using a microwave-assisted heating method. The NH2-UIO-66 (Zr)@MIP sensor with specific recognition sites for oxytetracycline was then acquired by modifying a molecularly imprinted polymer on the surface of NH2-UIO-66 (Zr). The introduction of NH2-UIO-66 (Zr) as both a signal tag and supporter can strengthen the sensitivity of the fluorescence sensor. Thanks to the combination of the unique characteristics of the molecularly imprinted polymer and NH2-UIO-66 (Zr), the prepared sensor not only exhibited a sensitive fluorescence response, specific identification capabilities and a high selectivity for oxytetracycline, but also showed good fluorescence stability, satisfactory precision and reproducibility. The fabricated sensor displayed a fluorescent linear quenching in the OTC concentration range of 0.05\u201340 \u03bcg mL\u22121, with a detection limit of 0.012 \u03bcg mL\u22121. More importantly, the fluorescence sensor was finally applied for the detection of oxytetracycline in milk, and the results were comparable to those obtained using the HPLC approach. Hence, the NH2-UIO-66 (Zr)@MIP sensor possesses great application potential for the accurate evaluation of trace oxytetracycline in dairy products.Developing sensitive and effective methods to monitor oxytetracycline residues in food is of great significance for maintaining public health. Herein, a fluorescent sensor (NH As a result, the establishment of LMOF-based sensors with specific recognition abilities and high selectivity is a vital method by which to achieve the accurate evaluation of target analytes in real samples.Luminescent metal organic frameworks (LMOFs), as rapidly developing novel-type organic\u2013inorganic porous crystal materials, have displayed wide application potential in sensing fields owing to their high specific surface area and porosity, intrinsic luminescence properties, as well as structure multiplicity ,2. Amongace area ,4,5,6. Ft effect . Wang et in milk . Althoug2-UIO-66 (Zr) with MIP in order to design fluorescent sensors, in which the introduction of MIP can promote the generation of customized binding sites complementary to the target analytes in terms of size, shape and functional group, thus improving the selectivity of the obtained sensor. For example, a MOF@MIP FL sensor (NH2-UIO-66@MIP), synthetized by encapsulating NH2-UIO-66 into the MIP, was successfully exploited for the ultrasensitive and highly selective detection of melatonin in juice [2-UIO-66/MIP) was constructed to selectively and effectively detect trace levels of 4-nitrophenol in drinkable water, as well as in environmental water [2-UIO-66) was made via decorating MIP on Zr-LMOF and was employed for the FL sensing of chloramphenicol in animal-derived food [Molecular imprinting technology (MIT) is a promising molecular simulation recognition technique that mimics the specific antigen\u2013antibody or enzyme\u2013substrate binding processes, and has attracted great attention in the past few decades. The formed molecularly imprinted polymer (MIP) not only possesses the ability to specifically recognize the detected molecules, but also has a high adsorption efficiency and strong stability, which makes it widely used in various fields  ,10,11,12in juice . A LMOF-al water . A turn-ved food . Therefo\u22121, respectively [For many decades, the abuse of antibiotics has been regarded as a global concern because antibiotic residues may constitute a threat to human health ,17. Oxytectively ,23,24. Aectively , liquid ectively , enzyme-ectively , high-peectively , fluoromectively  and so oectively ,31,32. H2-UIO-66 (Zr) for the selective and ultrasensitive FL monitoring of OTC. Consequently, in this work, a turn-off FL sensor (expressed as NH2-UIO-66 (Zr)@MIP) that combines a large surface area and the unique fluorescence properties of NH2-UIO-66 (Zr), as well as the high specificity of the imprinted layer, was developed for an assay of OTC using the inner filter effect (IFE). Herein, the NH2-UIO-66 (Zr) with an intense blue FL emission, as a signal tag and substrate material, was prepared via a simple microwave-assisted heating process and then covered with a molecularly imprinted layer. After removing the OTC template molecule, the NH2-UIO-66 (Zr)@MIP sensor with custom-made binding sites for the OTC was obtained. The modification of the MIP granted the sensor high selectivity, adsorption affinity and binding efficiency to OTC. Meanwhile, NH2-UIO-66 (Zr), as a luminous center and a carrier, endowed the proposed sensor with a desirable FL signal output and response sensitivity. Furthermore, its relatively uniform morphology, good optical properties, superior FL sensitivity, outstanding adsorption and binding performance, as well as its excellent specificity, were demonstrated via different characterizations. The established sensor was successfully used in the highly sensitive and selective determination of OTC in milk samples, confirming its practical applicability.Although some FL sensors that integrate the merits of LMOFs and MIP have been designed ,33,34,354, 99%) was purchased from Beijing Yinuokai Technology Co., Ltd. . Methacrylic acid , 2,2-azobisisobutyronitrile  and ethylene glycol dimethacrylate  were obtained from TCI Development Co., Ltd. . N, N-dimethylformamide (DMF), ethanol, glucose, sucrose, MnCl2\u00b74H2O, MgCl2\u00b76H2O, Zn(NO3)2\u00b76H2O, CaCl2, NaCl and KCl were supplied by Sinopharm Chemical Reagent Co., Ltd. . All reagents and chemicals used in this work were of at least analytical grade. The apparatuses utilized in this study are described in detail in the 2-aminoterephthalic acid , tetracycline , doxycycline , oxytetracycline , chlortetracycline , chloramphenicol , tyrosine (Tyr), histidine (His), serine (Ser), phenylalanine (Phe), arginine (Arg) and cysteine (Cys) were provided by Shanghai Macklin Biochemical Co., Ltd. . Zirconium chloride (ZrCl2-UIO-66 (Zr) refers to the microwave-assisted heating assay employed in a previous study with minor changes [4 and 500 mg of ATA were firstly dissolved in 60 mL of DMF, followed by ultrasonic treatment for 1 h. Next, the aforementioned reaction precursor solution was placed in a stainless steel Teflon-lined autoclave and heated to 120 \u00b0C for 24 h. After natural cooling, the deposition was attained via centrifugation, distributed in ethanol (30 mL), and heated at 100 \u00b0C for 30 min in a microwave synthesis reaction device. Subsequently, after dropping to ambient temperature, the obtained solid was centrifuged, and then the above microwave heating activation process was carried out again. Ultimately, the yellow product was acquired via vacuum drying (60 \u00b0C for 6 h) for later tests.The preparation process of NH2-UIO-66 (Zr)@MIP was fabricated according to a previous study, with slight modifications [2-UIO-66 (Zr)  and OTC  were completely dispersed in 30 mL of ethanol using ultrasonic treatment. Then, after the addition of MAA , the mixture was pre-polymerized for 50 min under continuous stirring. Subsequently, EGDMA  and AIBN  were successively introduced into the above synthesis system and stirred for 15 h in a water bath at 65 \u00b0C. Finally, the acquired polymer was centrifuged, eluted repeatedly via water/ethanol  to expunge OTC and dried under vacuum at 50 \u00b0C for 7 h. Meanwhile, the non-imprinting polymer (NH2-UIO-66 (Zr)@NIP), as a contrast material, was prepared according to the above steps in addition to not adding OTC.NHications . In the 2-UIO-66 (Zr)@MIP or NH2-UIO-66 (Zr)@NIP was scattered in 4 mL of PBS buffer solution (pH = 7) with various concentrations of OTC. After incubation for 30 min, the FL determination was performed under an excitation wavelength of 350 nm and the FL intensity of the sensing system at 455 nm was obtained. The specific recognition performance was appraised by adding other antibiotics with a similar structure or possible coexisting interfering substances instead of OTC under identical experimental conditions. The measurements of each experiment were carried out in triplicate.In brief, 1 mg of NH2-UIO-66 (Zr)@MIP, by spiking the proper concentration of OTC. Three parallel experiments were conducted on the milk samples of each concentration.Fresh pure milk bought from a local supermarket  was used to assess the practicability of the proposed FL method based on NH\u22121, 1 \u03bcg mL\u22121, 15 \u03bcg mL\u22121 and 25 \u03bcg mL\u22121) were vortically mingled with 4 mL of acetonitrile for 5 min. Subsequently, the mixture was centrifuged and the resulting supernatant was filtrated using a 0.22 \u03bcm microfilter to expunge protein precipitates. Finally, the above samples were dried using nitrogen and re-dispersed in 1 mL of PBS buffer solution (pH = 7) for FL determination.The spiked milk samples containing specific OTC concentrations were first prepared and placed overnight. Afterwards, the preprocessing of the samples was executed according to a previous study . In brieWith regard to HPLC determination, the extraction, purification and analysis procedures of milk samples were carried out according to Chinese National Standards (GB/T 22990-2008) , which w2-UIO-66 (Zr) with a bright blue fluorescence and large surface area was first fabricated via a self-assembly strategy using Zr4+ and ATA as precursors. Subsequently, a new biomimetic FL sensor based on MIP-coated NH2-UIO-66 (Zr) was prepared using the one-step aggregation method. The polymerization reaction was thermally initiated and completed in a water bath in the presence of OTC (template), NH2-UIO-66 (Zr) (fluorophore and supporter), MAA , EGDMA (cross-linker) and AIBN (initiator). During this process, OTC molecules and functional monomers were combined by hydrogen bonds. After eliminating the imprinted template OTC by using a suitable eluent, the NH2-UIO-66 (Zr)@MIP sensor with specific recognition cavities fitting the shape and functional group of OTC was finally achieved in order to selectively monitor the OTC. The existence of NH2-UIO-66 (Zr) as both a signal transducer and carrier granted the proposed sensor outstanding FL characteristics and good response sensitivity. The introduction of a molecularly imprinted layer not only preserved the sensitive FL signal of NH2-UIO-66 (Zr), but also endowed the obtained sensor with the ability to specifically recognize OTC. Consequently, the constructed NH2-UIO-66 (Zr)@MIP sensor integrated these superiorities of LMOFs and MIP. Moreover, in order to obtain NH2-UIO-66 (Zr)@MIP with an excellent fluorescent response and the ability to bind well to the OTC, the synthesis conditions, including the additive level of fluorophore, the molar ratio of OTC, MAA and EGDMA, and the polymerization time, were optimized (As portrayed in ptimized .2-UIO-66 (Zr), NH2-UIO-66 (Zr)@MIP and NH2-UIO-66 (Zr)@NIP were observed via SEM and TEM. SEM (2-UIO-66 (Zr) presented a uniform and smooth octahedron-like appearance, with a mean size of nearly 50 nm [2-UIO-66 (Zr) was also explored via the energy-dispersive spectrometer (EDS) spectrum (2-UIO-66 (Zr). These results demonstrated the successful synthesis of NH2-UIO-66 (Zr). As displayed in 2-UIO-66 (Zr)@MIP and NH2-UIO-66 (Zr)@NIP) appeared nearly spherical, with a particle size of approximately 250 nm (2-UIO-66 (Zr) due to the introduction of the molecular imprinting layer. The TEM images (2-UIO-66 (Zr) and possessed an archetypal core-shell structure, which evidenced that the polymers were successfully formed. In addition, the element mapping image of NH2-UIO-66 (Zr)@MIP (2-UIO-66 (Zr)@MIP sensor.The surface morphologies and structures of the fabricated NHTEM. SEM a, TEM @MIP  showed t2-UIO-66 (Zr), the characteristic peaks at 3492 and 3373 cm\u22121 can be attributed to the antisymmetric and symmetric stretching modes of -NH2, respectively [\u22121 originated from a C=C stretching vibration in the benzene ring of the ATA ligand [\u22121), Zr\u2013O (483 cm\u22121) and -OCO (1430 and 1384 cm\u22121) were also observed, indicating that the dehydroxylation phase in NH2-UIO-66 (Zr) was favorably formed thanks to the coordination of Zr4+ with ATA [2-UIO-66 (Zr)@NIP, the absorption peaks at 3544 cm\u22121 (-OH), 2988 and 2953 cm\u22121 (C=H), 1731 cm\u22121 (C=O), 1455 cm\u22121 (C=C), and 1260 and 1159 cm\u22121 (C\u2013O\u2013C) symbolized the presence of MAA  and EGDMA (cross-linker). Meanwhile, the Zr\u2013O vibration peaks  corresponding to the NH2-UIO-66 (Zr) appeared in NH2-UIO-66 (Zr)@NIP, which demonstrated the successful preparation of the non-imprinted polymer doped with NH2-UIO-66 (Zr) [2-UIO-66 (Zr)@MIP spectrum were very similar to those in the NH2-UIO-66 (Zr)@NIP spectrum, implying that NH2-UIO-66 (Zr)@MIP was triumphantly developed.The FT\u2013IR spectra were recorded in order to analyze the surface chemistry of the synthetic materials. As presented in ectively ,40. The A ligand ,15. The with ATA . For NH21430 and 84 cm\u22121 w-66 (Zr) . Additio2-UIO-66 (Zr) highly coincided with those reported in the literature, which showed that NH2-UIO-66 (Zr) with good crystallinity was triumphantly fabricated [2-UIO-66 (Zr)@MIP and NH2-UIO-66 (Zr)@NIP, the characteristic absorption peaks associated with NH2-UIO-66 (Zr) became unapparent, owing to the decoration of the surface molecularly imprinted shell, which helped to prove the successful preparation of the polymers [To analyze the crystallographic structure of the synthesized materials, XRD data were collected and are depicted in bricated ,14,43. Npolymers .2 adsorption/desorption isotherms of NH2-UIO-66 (Zr) and its imprinted polymer were evaluated, as shown in 2-UIO-66 (Zr), NH2-UIO-66 (Zr)@MIP and NH2-UIO-66 (Zr)@NIP, obtained via the Brunauer\u2013Emmett\u2013Teller (BET) analysis method, were 219 m2 g\u22121, 37 m2 g\u22121 and 28 m2 g\u22121, respectively. Compared to NH2-UIO-66 (Zr), the surface areas of NH2-UIO-66 (Zr)@MIP and NH2-UIO-66 (Zr)@NIP were clearly reduced after coating the imprinted layer [2-UIO-66 (Zr)@MIP in comparison to that of NH2-UIO-66 (Zr)@NIP, probably due to the existence of imprinted cavities after eliminating the template [In order to further investigate the surface characteristics of the resulting materials, the Ned layer ,35,45. Mtemplate .2-UIO-66 (Zr)@MIP) was triumphantly fabricated via combining the molecularly imprinted polymer with NH2-UIO-66 (Zr).The above-mentioned data signified that the FL sensor (NH2-UIO-66 (Zr)@MIP showed slightly lower FL intensity than NH2-UIO-66 (Zr) on account of decorating the MIP layer. However, NH2-UIO-66 (Zr)@MIP exhibited an intense symmetric FL emission peak corresponding to NH2-UIO-66 (Zr) at 455 nm under 350 nm excitation, which implied that the modification of the surface imprinting layer had no remarkable impact on the FL performance of NH2-UIO-66 (Zr). As a consequence, the synthesized sensor maintained the unique luminous property of NH2-UIO-66 (Zr).The luminescence performance of the developed sensor was firstly studied through FL spectra. As displayed in 2-UIO-66 (Zr)@MIP and NH2-UIO-66 (Zr)@NIP) to OTC were then conducted to explore the practicability of the established sensor (2-UIO-66 (Zr)@MIP presented a more conspicuous FL change than NH2-UIO-66 (Zr)@NIP, owing to its better binding capacity and specificity towards OTC. After eliminating OTC, the fluorescence of the polymers was restored and the FL spectrum of NH2-UIO-66 (Zr)@MIP was basically consistent with that of NH2-UIO-66 (Zr)@NIP, which indicated that the fabricated NH2-UIO-66 (Zr)@MIP sensor was viable for the determination of OTC.FL experiments measuring the response of the polymers (NHd sensor a. ClearlF0/F) of NH2-UIO-66 (Zr)@MIP and NH2-UIO-66 (Zr)@NIP towards the target OTC at different incubation times was recorded. Under the continuously increasing reaction time, the F0/F value of NH2-UIO-66 (Zr)@MIP increased quickly at first, reached the maximum at 30 min, and then tended to remain unchanged, which demonstrated that the detection system achieved adsorption equilibrium within 30 min. Therefore, 30 min was considered to be the optimal reacting time in consequent trials. The variation in the trend observed with regard to the FL response of NH2-UIO-66 (Zr)@NIP was analogous to NH2-UIO-66 (Zr)@MIP. Nevertheless, NH2-UIO-66 (Zr)@MIP possessed a higher FL response and adsorption efficiency than NH2-UIO-66 (Zr)@NIP at the identical reaction time, indicating that the generation of specific identification imprinted sites enhanced the binding affinity of NH2-UIO-66 (Zr)@MIP towards OTC.Adsorptive kinetics tests of the as-prepared polymers were performed to investigate the adsorption performance of the sensor. As shown in 2-UIO-66 (Zr)@MIP and the FL response of NH2-UIO-66 (Zr)@MIP towards OTC were studied in the case of not adding and adding OTC, respectively. As illustrated in 2-UIO-66 (Zr)@MIP first increased, then remained basically stable, and the highest FL intensity was apparently observed at pH = 7. In addition, the maximum FL response value (F0/F) was concurrently obtained at pH = 7, proving that NH2-UIO-66 (Zr)@MIP possessed the strongest adsorption binding efficiency to OTC. Thus, pH = 7 was chosen as the best pH for the sensing system in subsequent FL detection experiments.Next, the influences of the pH (5\u20139) on the fluorescence intensity of NH2-UIO-66 (Zr)@MIP under diverse ultraviolet (UV) light radiation times and storing times. As shown in 2-UIO-66 (Zr)@MIP exhibited an unapparent FL change after UV irradiation at 350 nm for 60 min, signifying the exceptional photo-bleaching resistance of the proposed NH2-UIO-66 (Zr)@MIP-based sensor. At the same time, the FL intensity of NH2-UIO-66 (Zr)@MIP remained steady within 60 days @MIP-based sensor had good optical properties and a good adsorption performance.The above experimental results confirm that the NH2-UIO-66 (Zr)@MIP and NH2-UIO-66 (Zr)@NIP after the addition of different levels of OTC. As portrayed in \u22121, the FL intensity of NH2-UIO-66 (Zr)@MIP was progressively quenched. Clearly, NH2-UIO-66 (Zr)@NIP showed an analogous FL change trend towards NH2-UIO-66 (Zr)@MIP. Nevertheless, compared with NH2-UIO-66 (Zr)@NIP, NH2-UIO-66 (Zr)@MIP presented a more noticeable FL quenching response when the same concentration of OTC was added (2-UIO-66 (Zr)@MIP. Furthermore, the relationship between the FL quenching signal (F0/F) and the concentration of OTC can be described via the Stern\u2013Volmer equation [COTC and SVK are the concentration of OTC and the FL quenching constant, respectively. F0 and F represent the FL intensity of the sensing system before and after adding OTC. The imprinting factor (IF), set as the specific value of KSV, NH2-UIO-66 (Zr)@MIP to KSV, NH2-UIO-66 (Zr)@NIP, was used as a key index to estimate the adsorption binding capacity of the NH2-UIO-66 (Zr)@MIP sensor towards OTC.Under the above optimum sensing conditions, the concentration responses of the as-synthesized FL polymers for OTC were assessed by collecting and analyzing the FL spectra of NHas added b, which equation ,47:F0/F 2-UIO-66 (Zr)@MIP and the OTC concentration (0.05\u201340 \u03bcg mL\u22121). The limit of detection (LOD) of 0.012 \u03bcg mL\u22121 was achieved on the basis of the standard 3bS/slope  [2-UIO-66 (Zr)@MIP had a more notable FL response change than NH2-UIO-66 (Zr)@NIP at an identical OTC dose, which emphasized the outstanding selectivity and adsorptive efficiency of NH2-UIO-66 (Zr)@MIP towards OTC. Simultaneously, the good specific recognition capacity of NH2-UIO-66 (Zr)@MIP was also authenticated by comparing the slopes of the corresponding standard linear equations of NH2-UIO-66 (Zr)@MIP  and NH2-UIO-66 (Zr)@NIP  @MIP sensor had a superior selective identification capacity and superior adsorption affinity for OTC., n = 9) ,48. Plai= 0.994) c,d. More2-UIO-66 (Zr)@MIP sensor towards the OTC molecule was investigated and discussed. The FL spectrum of NH2-UIO-66 (Zr)@MIP and the UV absorption spectrum of OTC are illustrated in 2-UIO-66 (Zr)@MIP almost did not overlap with the UV absorption spectrum of OTC, but there was a partial and effective overlap between the excitation spectrum of NH2-UIO-66 (Zr)@MIP and the UV absorption band of OTC. Therefore, the possible mechanism was initially determined as the inner filter effect (IFE), rather than FL resonance energy transfer (FRET) [2-UIO-66 (Zr)@MIP before and after OTC adsorption was analyzed. The FL emission decay curves are presented in 2-UIO-66 (Zr)@MIP showed a slight variation from 3.61 ns to 3.48 ns after OTC treatment, further demonstrating that the OTC-initiated FL quenching behavior was mainly caused by IFE.The potential FL sensing mechanism of the NHr (FRET) ,49. To br (FRET) ,51. Acco2-UIO-66 (Zr)@MIP-based sensor towards the OTC molecule to be better understood. As presented in 2-UIO-66 (Zr)@MIP was notably greater than that of other antibiotics with a similar structure, which was mainly owing to the formation of the special recognition cavities in NH2-UIO-66 (Zr)@MIP that utterly conformed the size, shape and functional group of OTC during the molecular imprinting process. Because there were no specific recognition sites corresponding to TET, DOX, CTC and CAP in NH2-UIO-66 (Zr)@MIP, the NH2-UIO-66 (Zr)@MIP sensor had a comparatively small FL response value (F0/F) to these analogs (2-UIO-66 (Zr)@MIP to selectively capture and effectively bind with these analogues in the detection process. Furthermore, compared with NH2-UIO-66 (Zr)@MIP, NH2-UIO-66 (Zr)@NIP, without specific recognition sites, generated a relatively low FL response to OTC and other analogues, which was attributed to the nonspecific adsorption between NH2-UIO-66 (Zr)@NIP and these analytes. The above results suggest that the introduction of highly selective imprinted sites endowed the NH2-UIO-66 (Zr)@MIP sensor with the ability to specifically identify OTC.The selectivity of the constructed FL sensing system was assessed by recording and contrasting the FL changes in the polymers to OTC and its structural analogues . The chemical structures of these mentioned antibiotics, which are first portrayed in  analogs b. TherefF0/F) of NH2-UIO-66 (Zr)@MIP to different concentrations of structural analogues were also studied to investigate the selectivity of the established sensor. As shown in F0/F) apparently increased after introducing OTC. In addition, there was no significant linear relationship between the concentration of the analogue and FL change (F0/F), which indicated that the constructed FL detection system had good selectivity for the target OTC.The FL response changes (2-UIO-66 (Zr)@MIP to specifically recognize OTC, a competitive adsorption test was conducted by adding the possible coexisting structural analogs  into the mixed system containing NH2-UIO-66 (Zr)@MIP and OTC. As revealed in 2-UIO-66 (Zr)@MIP displayed tiny FL variation even though the concentration of each analogue was twice that of OTC, demonstrating that the interference caused by the presence of the coexisting analogues in the sensing system was inconspicuous. The good specificity of NH2-UIO-66 (Zr)@MIP towards OTC was probably due to the existence of OTC-imprinted sites generated via hydrogen bond interaction, which improved the combination efficiency of the sensor to OTC, and inhibited the nonspecific adsorption of the coexisting analogs. Thus, the obtained sensor possessed gratifying selectivity and specificity for the target OTC.In order to further assess the ability of NH\u2212, NO3\u2212, K+, Na+, Ca2+, Zn2+, Mg2+, and Mn2+) and common amino acids , will directly influence the accuracy of the test results. Therefore, the ability of the NH2-UIO-66 (Zr)@MIP sensor to avoid interference was explored by introducing the above interfering analytes into the constructed FL sensing system in the presence and absence of OTC. As shown in \u22121 (5 times of OTC concentration), but the influence of these interfering substances on the FL intensity of NH2-UIO-66 (Zr)@MIP was minor, which was in accordance with the blank experimental group. After adding OTC, the FL of the sensing system was significantly quenched, indicating that these interfering species had a negligible effect on the FL detection of OTC. The above results indicated that the developed FL sensor exhibited excellent selectivity and specificity towards OTC, as well as superior anti-interference characteristics in a complicated environment, thus providing a feasible tool for the FL detection of OTC.Due to the matrix complexity of the practical samples, the potential coexisting interfering substances in the real detection process, such as sugars (glucose and sucrose), ions (Cl2-UIO-66 (Zr)@MIP method and HPLC means. Consequently, the spiking and recovery tests were performed by introducing different levels of OTC standards  into the milk samples, and the relevant analysis results are presented in The commercial milk bought from the local supermarket was taken as a practical sample in order to analyze and authenticate the applicability of the FL sensing approach created in this study. No OTC was found in the blank milk samples when using the NH2-UIO-66 (Zr)@MIP sensing method were also appraised by detecting the spiked samples using different concentrations of OTC standards . As shown in n = 6), respectively, indicating that the sensor had sterling reproducibility as well as good accuracy, and was suitable for the determination of OTC in real products.The intra-day and inter-day precisions of the established NH\u22121), a lower LOD (0.012 \u03bcg mL\u22121), a comparable recovery rate (93.56\u201398.21%) and an acceptable accuracy (RSD < 2.59%). The good performance of the NH2-UIO-66 (Zr)@MIP-based sensor came from the following aspects. On one hand, introducing NH2-UIO-66 (Zr), which has sterling FL characteristics and a large surface area, as the support improved the sensitivity of the proposed FL sensor. On the other hand, the integration of the surface-imprinted layer endowed the sensor with the ability to specifically identify and accurately absorb the target from the complicated matrix, which helped to avoid the tedious sample pretreatment process and to reduce the analysis time. Taken together, the constructed NH2-UIO-66 (Zr)@MIP-based sensor can be appropriately applied in order to quantitatively monitor trace OTC in a sophisticated system.The performance of the designed sensing assay was compared to some subsistent FL-based methods for OTC detection, the results of which are shown in 2-UIO-66 (Zr)@MIP) was successfully designed based on an amino-functionalized zirconium (IV) metal\u2013organic framework embedded in a molecularly imprinted polymer in order to selectively recognize and sensitively detect trace OTC. Because of the combination of MIP, with an excellent specific recognition ability, and NH2-UIO-66 (Zr), with unique fluorescent characteristics, the fabricated NH2-UIO-66 (Zr)MIP sensor showed exceptional sensitivity, excellent selectivity, desirable anti-interference capacity, as well as good precision during the process of detecting OTC. Additionally, the constructed FL sensing system was triumphantly employed in order to determine OTC in milk with satisfying results, displaying good practical application prospects. Therefore, it is expected that the proposed NH2-UIO-66 (Zr)@MIP-based sensor will provide a significant detection platform for OTC residue analysis in food safety evaluation.In summary, a novel turn-off fluorescent biomimetic sensor (NH"}
{"text": "After the publication of our paper, we noticed an error in Fig. 2G. Specifically, a panel of representative images were misplaced into the EdU results (si-NC group of Huh-7 cells) during the process of our final figure assembly. We carefully verified the original data again, corrected the mis-incorporated images and provided the correct version of Figure 2G below.The conclusion of our research was not affected by the error. In this respect, all authors have agreed to the erratum, and we sincerely regret any annoyance the negligence in our work may have caused."}
{"text": "In \"Predictors of Playing Augmented Reality Mobile Games While Walking Based on the Theory of Planned Behavior: Web-Based Survey\" :e191) the authors noted one error.In Table 6, the results for the factor \u201cEnjoyment\u201d in the third block were shifted one column to the right. The original table can be seen in The correction will appear in the online version of the paper on the JMIR Publications website on June 19, 2023, together with the publication of this correction notice. Because this was made after submission to PubMed, PubMed Central, and other full-text repositories, the corrected article has also been resubmitted to those repositories."}
{"text": "Atxn1154Q/2Q andAtxn12Q/2Q mousemodels.\u201d When describing the mouse amino acid locations for the two mutationsmade in the AXH domain of ATXN1, we erroneously stated that human V591 and S602correspond to mouse V620 and S631, respectively. The corrected text should read\u201cPlease note that human V591 and S602 correspond to mouse V566 and S577,respectively.\u201d This has now been updated online. The authors apologize for theerror.In the originally published paper, there was one error in the STAR Methodssection \u201cGeneration of"}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Owing to the fact that the contentious data in the above article had already been submitted for publication prior to its submission to"}
{"text": "Retraction Note:J Exp Clin Cancer Res38, 139 (2019)https://doi.org/10.1186/s13046-019-1134-yThe Editor-in-Chief has retracted this article. Concerns have been raised about Fig.\u00a03a, specifically:The 0h control panels for U87 and U251 appear to be identicalThe 0h NF 25\u00b5M panels for U87 and NF 25\u00b5M appear to be identicalThe 0h NF 30 \u00b5M panels for U87 and U251 appear to partially overlapThe 24h control panels for U87 and U251 appear to be identicalThe 24h NF 25 \u00b5M panels for U87 and U251 appear to partially overlapThe 24h NF 30 \u00b5M panels for U87 and U251 appear to partially overlapThe 48h control panels for U87 and U251 appear to partially overlapThe 48 NF 25 \u00b5M panels for U87 and U251 appear to be identicalThe Editor-in-Chief therefore no longer have confidence in the results and conclusions of this article.Authors Zizhuo Li and Xiuhua Yang agree with this retraction. The other authors have not responded to correspondence regarding this retraction."}
{"text": "Subretinal injection is performed in vitreoretinal surgery with two main aims, namely, the subretinal delivery of therapeutic agents and subretinal injection of fluid to induce a controlled and localized macular detachment. The growing interest in this technique is mainly related to its suitability to deliver gene therapy in direct contact with target tissues. However, subretinal injection has been also used for the surgical management of submacular hemorrhage through the subretinal delivery of tissue plasminogen activator, and for the repair of full-thickness macular holes, in particular refractory ones. In the light of the increasing importance of this maneuver in vitreoretinal surgery as well as of the lack of a standardized surgical approach, we conducted a comprehensive overview on the current indications for subretinal injection, surgical technique with the available variations, and the potential complications. Subretinal injection is a delicate surgical maneuver whose application in vitreoretinal surgery is progressively increasing. This is mainly due to the suitability of subretinal injection to deliver a controlled amount of therapeutic agent directly to the retinal pigment epithelium (RPE) cells and photoreceptors. Additional advantages include the need for a reduced concentration of drug and the delivery in an immune-privileged and anatomically closed subretinal space ,2. FurthBased on this, subretinal injections are now the established preferred route of administration of gene therapy for the treatment of inherited retinal diseases (IRDs), where RPE cells and photoreceptors are primarily affected . In termDespite the growing role of subretinal injection in ophthalmic surgery, there is no standardized surgical technique, and different variations are described in the currently available literature . With thInherited retinal diseases (IRDs) comprise a small proportion of all retinal diseases. They are a group of diseases with a multitude of phenotypic expressions, wherein the etiology is a genetic abnormality within the cells of the retina or choroid ,10. SincSubretinal injection is the preferred route of administration of gene therapy as it is superior to the other potential routes, which include delivery into the anterior chamber and vitreous cavity ,9,11.Indeed, the subretinal delivery of a therapeutic agent allows the direct delivery to the targeted disease cells with less overflow into other uninvolved sites, low immunogenicity, good biodistribution control, and the overcoming of limitations of other routes of administration, such as the poor penetration of the viral vector through the internal limiting membrane (ILM) in case of intravitreal injection ,12,13.Each patient should be assessed on an individual basis through a comprehensive assessment including clinical appearance and genotyping, in order to evaluate the suitability for the current available gene therapies.The patient may be pretreated with oral corticosteroids to reduce the immune response to viral vectors, which has been described with retinal gene therapy . The steThe standard technique for subretinal injection of gene therapy involves carrying out three-port 23- or 25-gauge (G) vitrectomy (PPV). After inducing the posterior vitreous detachment (if needed) and completing the core and peripheral vitrectomy along with peripheral retina examination, it should be ensured that the injection site is completely clear of any residual vitreous. This maneuver can be facilitated by the use of diluted triamcinolone acetonide injected intravitreally to the site of interest.The site of gene therapy injection should be selected taking care to avoid areas of advanced retinal atrophy, epiretinal membranes (ERMs), blood vessels, and the papillomacular bundle . If needThere are different ways in which the subretinal injection can then be performed, namely, manually or automatically, and with or without formation of a pre-bleb ,17 AutomCreation of a pre-bleb with balanced salt solution (BSS) prior to the subretinal injection of gene therapy vector has the potential benefit of conserving viral vector . Indeed,A 23- or 25-G cannula with a retractable cannula, with size variable from 38- to 41-G, is then attached to the VFIM syringe ,16,20. TThe injection pressure is then set on the machine, more commonly between 12\u201318 psi ,16. YounA useful adjunct during the process of subretinal injection can be the microscope-integrated optical coherence tomography (MI-OCT). The MI-OCT reticule can be positioned close to the injection site prior to insertion of the cannula. Once the injection begins, if the cannula is correctly placed, the immediate separation and elevation of the retina from RPE is seen. MI-OCT allows monitoring of successful bleb creation with the \u201cfleur de lis\u201d sign, with the central \u201cstem\u201d made by the subretinal cannula and the petals on either side made by the adjacent retina elevated by the subretinal bleb . MI-OCT If the gene vector is injected after the formation of the pre-bleb, the same retinotomy should be used for the vector injection. Three main complications can be associated with the creation of the pre-bleb and the subsequent gene therapy injection. In particular, a second retinotomy can be created accidentally or the first retinotomy can be widened. leading to an increased risk of reflux of the vector. This can potentially not only reduce the drug in the subretinal space where it is needed, but also increase the risk of immune reaction to the viral capsids escaping into the vitreous cavity. Finally, as mentioned above, the higher subretinal volume can increase the risk of retinal overstretching and, potentially, FTMH formation if the fovea is detached.If, no pre-bleb has been created, the vector itself is used to detach the retina and create the bleb . SometimAfter the drug has been delivered into the subretinal space, a vitreous cavity washout is performed to remove any vector that has refluxed into the vitreous cavity ,16,21. ASome limitations of subretinal injections include physiological surgeon tremor, and instrument drift. A potential future development was investigated by Ladha et al., who showed that robotic-assisted subretinal injection helps reduce the aforementioned surgeon-related factors when performing subretinal injections in artificial retina models . SeveralAn alternative to the traditional subretinal injection technique following vitrectomy is being explored currently using an orbital subretinal delivery system (Gyroscope Therapeutics Orbit SDS\u2122). In this technique, a flexible cannula mounted on a delivery system is introduced into the suprachoroidal space through a scleral incision and progressed towards the posterior pole using MI-OCT, before gently introducing the microneedle into the subretinal space . This suSubmacular hemorrhage is a harmful and sight-threatening complication associated with neovascular age-related macular degeneration and polypoidal choroidal vasculopathy, but, less commonly, it can also be associated with ocular trauma, pathological myopia, or rupture of retinal arterial microaneurysm . The accSeveral therapeutic options, and combinations of them, have been proposed for the management of submacular hemorrhage, including antivascular endothelial growth factor (VEGF) agents, photodynamic therapy, pneumatic displacement using expansile gases, intravitreal injection of tPA, and PPV. PPV in this context allows the performance of different maneuvers, such as subretinal injection of tPA, active drainage of subretinal blood, RPE patch grafting, macular translocation, or removal of the choroidal neovascularization ,33.The rationale of the subretinal injection of tPA relies on the thrombolytic activity of this serine protease which binds the fibrin, forming a complex able to activate the plasminogen to plasmin, and, thus, has the ability to lyse the blood clot. By liquefying the blood, tPA can not only facilitate its drainage/displacement but also reduce the risk of iatrogenic damage to photoreceptors during clot removal as well as the need for large retinotomies and the associated risk of retinal detachment, epiretinal membrane (ERM), and proliferative vitreoretinopathy .The use of subretinal tPA was first described by Peyman et al.  and invoIn addition, several surgical variants have been described and multiple aspects of this surgical technique are still not standardized, such as the site of injection, the dose of tPA, the need to drain the subretinal blood, and the use of intraoperative adjuvants.Different sites have been proposed for the injection, including the superior edge of the SMH ,39 and tThe concentration of tPA used is more commonly 12.5 \u03bcg/0.1 mL , but canRecently, the first in-human randomized controlled trial compared surgical outcomes  of robot-assisted versus conventional manual subretinal injection of tPA for SMH . This piThe subretinal injection of BSS to induce a macular detachment has been proposed as surgical option for the primary or, more commonly, secondary repair of FTMH . The mecSubretinal injection of BSS for FTMH repair is usually facilitated through standard 23- or 25-G PPV . After PSubretinal injection can be associated with different intraoperative and postoperative complications; however, the exact rates of these complications have not been established due to the paucity of patients treated and of studies analyzing long-term outcomes.Subretinal injection can cause iatrogenic RPE damage/irregularities due to direct mechanical trauma, both from the instrumentation and the flow rate of the therapeutic agent/BSS ,20,21,55Another severe complication that may occur is the formation of FTMH, usually as a result of overstretching of the fovea during the injection ,21,25,55Finally, as the subretinal injection is performed in the context of PPV, additional generic complications can be associated with the whole procedure, such as iatrogenic retinal tears, cataract formation, alterations of intraocular pressure, retinal detachment, endophthalmitis, bleeding, and vision loss .There are a number of potential complications that are specifically associated with subretinal gene therapy injection. One of the main complications specific of subretinal gene therapy is the reflux of viral vector and the potential subsequent intraocular inflammation ,14,15. IRecently, the development of progressive perifoveal chorioretinal atrophy, not related to the site of injection, has been described as a postoperative complication of the subretinal injection of voretigene neparvovec-rzyl; however, no predisposing or intraoperative factors have been so far associated with this complication . AtrophiSubretinal injection is now an established technique for drug delivery into the subretinal space, in particular due to the progressive evolution of gene therapy as well as, more recently, cell therapy. Indeed, ongoing trials are evaluating the therapeutic potential of therapies based on the delivery into the subretinal space of embryonal stem cells (hESCs) and human-induced pluripotent stem cells (hiPSCs) in eyes affected by age-related macular degeneration and Stargardt disease ,62. The"}
{"text": "Retraction Note: Journal of Autism and Developmental Disorders (2021) 52:2627\u2013264310.1007/s10803-021-05120-7The Publisher and the Editors-in-Chief are retracting this article. After publication concerns were raised with respect to the methodology used in this article. Post-publication review by a number of experts in the field has confirmed the following:Misrepresentation of the incidence of autism and insufficient attention given to various other factors that might account for apparent changes in ratesUse of unrepresentative dataNo valid justification for the mechanisms proposed for preventionArbitrary and insufficiently justified use of the birth cohort 1931 as an origin for the time trendUse of higher estimates and assumptions that inflated costs, together with failure to consider discrete events that occurred in referent years, including changes in definitions, alternative surveillance methods, and alternative explanations which may have contributed to changes in diagnosis.In addition, the Conflict of Interest statement does not accurately reflect the non-financial interests of the authors.The Editors-in Chief therefore no longer has confidence in the conclusions presented. Mark Blaxill, Toby Rogers and Cynthia Nevison disagree with this retraction."}
{"text": "Open Biol.9, 190095. (Published online 4 September 2019). (doi:10.1098/rsob.190095)Following the publication of \u2018MALAT1 promotes gastric adenocarcinoma through the MALAT1/miR-181a-5p/AKT3 axis\u2019, the Editorial team have concerns regarding the validity of the data used in this study.We are issuing an expression of concern here and investigating this as a matter of urgency; we will notify readers as to the results of our investigation as soon as possible."}
{"text": "There is an error in"}
{"text": "Leukemia 10.1038/s41375-022-01517-0, published online 15 February 2022Correction to: Owing to errors introduced during the proofreading process, the label \u00ab CB-ECFC \u00bb was erroneously added to the Figure."}
{"text": "Shalan  The Royal Society of Chemistry is publishing this Expression of concern in order to alert readers that concerns have been raised regarding the reliability of the FESEM data in Fig. 3c, XPS data in Fig. 4a and c, the EQE spectra in Fig. 5b, and the Nyquist curves in Fig. 6b. An investigation is underway, and an Expression of concern will continue to be associated with the article until a final outcome is reached.Jeremy Allenth November, 202320Nanoscale Advances.Executive Editor,"}
{"text": "II, PdII and PtII tetrathiolate bridges\u2019 by Manuel Quiroz et al., Chem. Sci., 2023, 14, 9167\u20139174, https://doi.org/10.1039/D3SC01546G.Correction for \u2018Magnetic coupling between Fe(NO) spin probe ligands through diamagnetic Ni The authors regret that a co-author, Zachary Martinez, was omitted in error from the author list of the published article.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "There was an error in the original publication . In the In Table 1, a correction is needed for the tetracycline resistance breakpoints: \u201c6\u201d should be replaced with \u201c16\u201d.The authors apologize for any inconvenience this change may cause. The authors state that the scientific conclusions are unaffected because the correction involves a typing error that was not caught during proofreading.This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "Correction: Animal Cognition  10.1007/s10071-023-01788-9Unfortunately the authors given name and family name were swapped and the correct names are given below. The affiliation \"Research Station Haidlhof, Comparative Cognition, Messerli Research Institute, University of Veterinary Medicine Vienna, Austria\" is added. The Electronic Supplementary Materials are added. Some references were missing the DOIs and are included which is given below. The original article has been corrected.Elisabeth Suwandschieff.Amelia Wein.Remco Folkertsma.Thomas Bugnyar.Ludwig Huber.Raoul Schwing.Supplementary file1 (PDF 411 KB)Supplementary file2 (PDF 517 KB)Below is the link to the electronic supplementary material."}
{"text": "Recent studies described 2\u20134 Hz oscillations in the hippocampus of rats performing stationary locomotion on treadmills and other apparatus. Since the 2\u20134 Hz rhythm shares common features with theta (5\u201312 Hz) oscillations\u2014such as a positive amplitude-running speed relationship and modulation of spiking activity\u2014many have questioned whether these rhythms are related or independently generated. Here, we analyzed local field potentials and spiking activity from the dorsal CA1 of rats executing a spatial alternation task and running for ~15 s in a wheel during the intertrial intervals both before and after muscimol injection into the medial septum. We observed remarkable 4-Hz oscillations during wheel runs, which presented amplitude positively correlated with running speed. Surprisingly, the amplitude of 4-Hz and theta oscillations were inversely related. Medial septum inactivation abolished hippocampal theta but preserved 4-Hz oscillations. It also affected the entrainment of pyramidal cells and interneurons by 4-Hz rhythmic activity. In all, these results dissociate the underlying mechanism of 4-Hz and theta oscillations in the rat hippocampus. The rodent hippocampus expresses abundant rhythmic activity across distinct and sometimes overlapping frequency ranges . Theta  band emerge during quiet behaviors and slow-wave sleep episodes but are typically suppressed during locomotor activity , 18. TheRats performed a spatial alternation task on a U-shaped maze and ran for ~15 s on a wheel during the intertrial intervals . ConsistAnimals ran faster at the wheel , which cNext, we evaluated how medial septum inactivation affects 4-Hz and theta oscillations in the wheel. Muscimol injection reduced the running speed on the wheel , with noWe then evaluated whether the effects of medial septum inactivation on 4-Hz and theta oscillations were dependent on running speed in the wheel. Muscimol injection did not affect the 4-Hz amplitude-running speed relationship, while reduced theta amplitude . NoteworWe evaluated autocorrelograms and power spectra of the spiking activity of putative interneurons and pyramidal cells during maze and wheel runs. Corroborating previous studies, autocorrelograms of spiking activity during maze runs presented strong rhythmicity in the theta band . We found that theta and 4-Hz instantaneous amplitudes were inversely related (rho = -0.28), which differed from previous reports using a virtual reality apparatus . These rTo evaluate this possibility, we tested whether pharmacological inactivation of the medial septum through intracerebral microinjections of muscimol affected hippocampal 4-Hz oscillations. As expected , 21, musIt is still unclear why 4-Hz oscillations are expressed in stationary locomotion but not usually observed during translational running conditions. Previous studies presented preliminary data on speed-modulated 4-Hz during wheel runs , 7. HoweTheta oscillations dominate the hippocampus during translational locomotion, with amplitude and frequency positively associated with running speed and acceleration , 23. WheIt is also unknown whether 4-Hz oscillations observed during stationary runs relate to the slower theta oscillations typically at frequencies around 5 Hz observed spontaneously or in response to stimuli in urethane-anesthetized rodents . CurrentFinally, the present work provides pharmacological and electrophysiological evidence that hippocampal 4-Hz and theta oscillations are independently generated during stationary locomotion.http://datadryad.org/ under a public domain dedication license.The dataset used in this study was previously acquired at the Pastalkova Lab on the Janelia Research Campus  and madeTwo 64-channel linear silicon probes (Neuronexus or Janelia RC) were bilaterally implanted at the dorsal CA1 area  of the rat hippocampus . Local field potentials (LFP), spiking activity, and digital video recordings were obtained during a delayed spatial alternation memory task in a U-shaped maze coupled to a running wheel in which animals ran (~15 s) during the intertrial intervals. Electrophysiological and behavioral recordings were obtained before  and after  muscimol microinjections into the medial septum. Detailed experimental procedures can be found in previous publications , 27.All data analyses were performed using custom-made and built-in routines in MATLAB . First, LFP recordings were notch-filtered between 55 Hz and 65 Hz to remove 60 Hz electrical noise. LFP signals were visually inspected to detect time intervals presenting electrical or movement artifacts. Next, time intervals in which the amplitude of LFP signals was larger than two times the standard deviation were excluded from further analysis (only recordings from rat A943 presented artifacts). Epochs presenting locomotion speed on the maze and in the wheel higher than 10 cm/s were further analyzed.We used the \u201ceegfilt\u201d function  to obtaThe rhythmicity of interneurons\u2019 and pyramidal cells\u2019 spiking activity was estimated through autocorrelograms (ACG) and power spectral densities (PSD) of spike times. Only neurons with an average firing rate larger than 1 Hz during maze and wheel runs were further analyzed. We used the \u201cxcorr\u201d function  or median and quartiles over trials, as indicated. We used the Shapiro-Wilk test to evaluate data normality. The Wilcoxon signed-rank (WSR) test or paired t-test was used to compare maze and wheel running conditions. The Wilcoxon rank-sum (WRS) test or Student\u2019s t-test was used comparing wheel runs before and after muscimol injections, and between wheel runs previous to correct and incorrect choices. The \u201ccorr\u201d function (option type \u201cSpearman\u201d) from the Statistics and Machine Learning Toolbox was used to obtain the Spearman\u2019s rank-based correlation coefficients (rho) between speed-amplitude and speed-frequency at the 4-Hz and theta bands  and 4-Hz-filtered signals (cyan) recorded during maze and wheel runs before  and during maze and wheel runs after  muscimol administration. The upper, middle, and lower panels depict LFP signals recorded from three different rats . Only epochs of running speed larger than 10 cm/s are shown.(TIF)Click here for additional data file.S2 Fig(A) Peak frequency within the 4-Hz band during maze and wheel runs . (B) Peak frequency within the theta band during maze and wheel runs . ** indicate p < 0.01 at the WSR test.(TIF)Click here for additional data file.S3 Fig(A) Percentage of correct choices before  and after  muscimol administration into the medial septum . (B) The absolute number of correct (green) and incorrect (blue) choices before  and after muscimol injection . (C) Histograms of 4-Hz band power (left) and theta band power (right) during wheel runs previous to correct (green) and incorrect (blue) choices. (D) Distribution of 4-Hz peak frequency (left) and theta peak frequency (right) during wheel runs before correct (green) and incorrect (blue) trials.(TIF)Click here for additional data file.S4 Fig(A) Scatter plots of running speed and the instantaneous amplitude of 4-Hz oscillations before and after muscimol from individual rats. The upper, middle, and lower panels show data from rats A498, A543, and A943, respectively. The individual rho- and p-values are A498: Pre, rho = 0.39, p < 0.01; Post, rho = 0.41, p < 0.01. A543: Pre, rho = 0.25, p < 0.05; Post, rho = 0.57, p < 0.01. A943: Pre, rho = 0.36, p < 0.01; Post, rho = 0.08, p = 0.062. (B) Scatter plots of running speed and the instantaneous amplitude of theta oscillations before and after muscimol. A498: Pre, rho = 0.38, p < 0.01; Post, rho = 0.17, p < 0.01. A543: Pre, rho = 0.53, p < 0.01; Post, rho = 0.53, p < 0.01. A943 Pre, rho = 0.03, p = 0.057; Post, rho = 0.12, p < 0.01.(TIF)Click here for additional data file.S5 Fig(A) Speed distributions in subsets of wheel runs ranging from 55 cm/s to 63 cm/s before (red) and after (blue) muscimol injection . (B) Average power spectra at 0\u201312 Hz during wheel runs before (red) and after (blue) muscimol injection in subsets of trials matched for running speed. Solid lines represent the mean and dashed lines represent \u00b1 SEM. (C) Boxplots showing the distribution of power in the 3\u20135 Hz band during wheel runs before and after muscimol injections in the same subsets of trials as before . (D) Distribution of power in the theta (6\u201310 Hz) band during wheel runs before and after muscimol injections in the same subsets of trials as before . ** indicate p < 0.01 at the WRS test.(TIF)Click here for additional data file.S6 Fig(A) Relationship between 4-Hz and theta amplitude in the wheel before  and after  muscimol injection. (B) Relationship between 4-Hz and theta peak frequency in the wheel before  and after muscimol injection .(TIF)Click here for additional data file.S7 Fig(A) ACG amplitudes of interneurons\u2019  and pyramidal cells\u2019  spikes at the 4-Hz frequency range. (B) ACG interpeak intervals of interneurons\u2019  and pyramidal cells\u2019  spikes at the 4-Hz frequency range. Red and blue bars depict wheel runs before and after muscimol injections, respectively.(TIF)Click here for additional data file."}
{"text": "This article has been corrected at the request of the submitting author to change a minor typo.The last sentence of the introduction has been changed from \u201cOne severe complication of EMH is cord compression, which could result in including motor and sensory impairment\u201d to \u201cOne severe complication of EMH is cord compression, which could result in motor and sensory impairment\u201d.The authors deeply regret that this error was not identified and addressed prior to publication."}
{"text": "Cgena3/CgENA3 and that of \u0394Cgena4/CgENA4 on CM medium supplied with 0.6 M KCl. The corrected Figure 3 appears below. The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated.In the original publication , there w"}
{"text": "Sci., 2021, 12, 15533\u201315542, https://doi.org/10.1039/D1SC05112A.Correction for \u2018Multi-stimuli programmable FRET based RGB absorbing antennae towards ratiometric temperature, pH and multiple metal ion sensing\u2019 by Kavita Rani  The unit of the temperature sensitivity should be %\u00b0CThe Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "The authors regret that the original version of our paper, unfortunately, contained incorrect pictures in Figure 2, where the GADPH bands were mistakenly used for similar experiments. The correct version of Figure 2 is shown below.The correction made in this erratum does not affect the original data and conclusions. The authors apologize for any inconvenience that the errors may have caused."}
{"text": "Huang  The authors regret that funding support from grant UG3CA244697 was mistakenly included in the Acknowledgements section. The correct Acknowledgements section is given below:\u00a0The research reported here was supported by the National Cancer Institute of the National Institutes of Health under award number R21CA251052 and by the National Institute of General Medical Sciences of the National Institutes of Health under award number R21GM138947. OE is supported by UL1TR002384, R01CA194547, P01CA214274 grants from the National Institutes of Health and LLS SCOR grants 180078-02, 7021-20, 180078-01. This work was performed in part at the Cornell NanoScale Facility, a member of the National Nanotechnology Coordinated Infrastructure (NNCI), which is supported by the National Science Foundation (Grant NNCI-2025233). The authors thank Dr. Ye Fang (Corning Inc.) for insightful discussions on the experimental design using PAR peptides.\u00a0The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "In addition to **1**, the affiliation(s) should be **1,2**. The newly added affiliation 2 should be: \u201cInstitute for Public Health, Charit\u00e9\u2013Universit\u00e4tsmedizin Berlin, Charit\u00e9platz 1, 10117 Berlin, Germany\u201d.In the published publication , there wThe authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. The original publication has also been updated."}
{"text": "Error in FigureFigure 5 as published. The images shown for the control group in 24 h are incorrect; the images for the control group in 48 h were inadvertently inserted because the two images are similar. The corrected Figure 5 appears below. The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated.In the original publication , there w"}
{"text": "Retraction Note: Child and Adolescent Psychiatry and Mental Health (2023) 17:710.1186/s13034-022-00550-2The Editors-in-Chief have retracted this article because the authors have informed them that, after publication, they became aware that there were errors in some portions of the software database used for the analysis of statistical data. These errors have altered the major conclusions, including significant results presented in the text and tables. The authors have been invited to submit a new manuscript for peer review. All authors agree with this retraction."}
{"text": "Retraction note: Nanoscale Research Letter\u00a0(2021) 17:2110.1186/s11671-021-03640-wThe Editors in Chief have retracted this article. After publication, concerns were raised regarding lack of scale for tumours in Fig.\u00a06A and poor quality of Western blots. Furthermore, ECC-1 cell line has been reported as contaminated by Ishikawa. The authors did not respond to requests to supply raw data or the ethics permit. The Editors, therefore, have lost confidence in the integrity of the article's findings. The authors did not respond to any correspondence from the Editors about this retraction."}
{"text": "The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates. The authors contacted the Editorial Office regarding a duplication in Figure 3C between the A549 migration vector image and the invasion vector image. A corrected image, which also includes the replacement of the Figure 3C STEAP1 panels, has been provided and is under review by the Editorial Board, and communication remains in progress regarding the western blot data of the figures and the raw data provided by the authors."}
{"text": "In the original publication , there wThe number of the \u201815\u201319 years\u2019 row in Table 3 was 31 instead of 30. The number and percentage for the \u2018Not satisfied\u2019 row in Table 4 were 0 instead of 1. The number of the \u2018Satisfied\u2019 row in Table 4 was 83 instead of 84. A \u2018No answer\u2019 row in Table 4 was added, with the number and percentage of 1. The number in the \u2018Somewhat easy\u2019 row in Table 5 was 28 instead of 29. The corrected The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "A rare case of tumor-to-tumor metastasis: metastatic lobular breast carcinoma to clear cell renal cell carcinoma\u201d published on 12 June 2023. This expression of concern has been posted while Pathology and Oncology Research awaits further clarification from the authors. It will be updated accordingly after that time.Following publication, the authors contacted the Editorial Office stating that the findings reported in the article are no longer supported by the analyses. With this notice, Pathology and Oncology Research states its awareness of concerns regarding \u201c"}
{"text": "Open Biol.9, 180227 (Published online 24 July 2019). (https://dx.doi.org/10.1098/rsob.180227)Following an investigation, we have found duplicates in the figures presented (notably fig. 2. (f) \u2018A transwell migration assay was conducted to analyse the migratory capacity of A549 and H1299 cells transfected with the miR-4262 mimics or inhibitor at 18 h.\u2019). This paper has been identified among of a set of papers that present significant text and data duplication and therefore the data reported in this article are unreliable. The authors have not been able to supply the raw data as requested, thus, the editors consider the conclusions of this article to be invalid. The authors have not responded to correspondence about this retraction.https://royalsocietypublishing.org/doi/10.1098/rsob.200165.The image integrity standards and policies for the journal can be found here: Jonathon Pines FRSOpen Biology.Editor-in-Chief,"}
{"text": "The journal retracts the 17 June 2021 article cited above.Following publication, concerns were raised regarding the validity of the data in the article. The authors failed to provide the raw data or a satisfactory explanation during the investigation, which was conducted in accordance with Frontiers\u2019 policies. Given the concerns, and the lack of raw data, the editors no longer have confidence in the findings presented in the article.This retraction was approved by the Chief Editors of Frontiers in Molecular Biosciences and the Chief Executive Editor of Frontiers. The authors have not responded to correspondence regarding this retraction."}
{"text": "An independent expert has viewed the corrected data for This correction supersedes the information provided in the Expression of Concern related to this article.The authors regret additional errors in the manuscript.Mn,NMR and Mn,GPC should be \u00d710 kg mol\u22121.In Table 1 the units for On page 19451, in the left column, in paragraph 2, line 9 and in the right column, in paragraph 3, line 10 the text \u2018(dimethylamino)ethyl methacrylate (DMAEMA)\u2019 should have been written as \u20182-(dimethylamino)ethyl methacrylate (DMAEMA)\u2019.The authors and the Royal Society of Chemistry apologise for these errors and any consequent inconvenience to authors and readers."}
{"text": "Similarly, researchers have resorted to virtual conferences and meetings (2). This shift has fueled technological advancements and made individuals more proficient in virtual environments (3).The COVID-19 pandemic has drastically transformed communication methods. Face-to-face interactions became extremely limited, forcing students to miss once-in-a-lifetime opportunities (2). These gatherings were useful because they eliminated geographical and administrative barriers (4). Moreover, many researchers currently prefer hybrid meetings to other platforms, and they are expected to become the new norm after the pandemic (5). Researchers may prefer to attend meetings virtually rather than in person, because virtual attendance is more convenient and efficient than traveling to a conference venue (4). Although hybrid meetings have numerous benefits, face-to-face meetings have two distinct advantages.As health restrictions are gradually relaxed, hybrid meetings that combine in-person and virtual attendance are becoming increasingly common First, in-person communication is easier and more casually initiated as people are in close proximity. Face-to-face communication allows for an unplanned conversation with someone you did not intend to speak with and discussion of topic you had never considered before. Therefore, informal conversations that occur unintentionally, such as those that occur during meals or social gatherings, can occasionally lead to new ideas and networking opportunities. A conversation with a coworker from another laboratory who is seated next to you could spark new ideas and cross-laboratory collaborations. However, during online conversations, numerous impediments to casual \u201cchatting\u201d exist. Thus, while online meetings are convenient and efficient, in-person interactions are required to spark creativity and establish new relationships.Second, physical encounters involving multiple senses provide people with new perspectives. For example, traveling to a new location for attending an academic conference or studying at another institution, can teach you about local culture and social structures. Understanding and recognizing cultural differences will broaden one\u2019s horizons as a person and researcher. Grasping the social context of science allows researchers to focus on how their work benefits the society. Thus, online meetings can offer fresh perspectives; however, the information we receive is limited to visual and auditory cues. Furthermore, attending meetings in unfamiliar locations may lead us to step outside our comfort zones.To summarize, hybrid meetings offer flexibility and ease of communication; however, it is important to strike a balance between the convenience of virtual attendance and the benefits of face-to-face interaction. Hence, in-person meetings should not be neglected in pursuit of convenience and simplicity with hybrid meetings.NoneThe authors are grateful to their colleagues, specifically those in clinical residency training, for their helpful discussions. The authors are also thankful to Paperpal  and ChatGPT  for providing primary language editing.Both authors conceptualized the manuscript. KT wrote the original draft and SS critically edited it. Both authors read and approved the final version of the manuscript.Not applicable."}
{"text": "Sci., 2017, 8, 7457\u20137463, https://doi.org/10.1039/C7SC03351F.Correction for \u2018Self-quenched ferrocenyl diketopyrrolopyrrole organic nanoparticles with amplifying photothermal effect for cancer therapy\u2019 by Pingping Liang  It has come to our attention that some errors have been found in Fig. S11. The H&E staining images of the Heart, Liver, and Lung  and Lung  in Fig. S11 of the published work were misused when editing the photos. The mistake was found by the authors after the paper was published online. The correct Fig. S11 is given below. The results and conclusions of this paper are not affected by this correction.Fig. S11 Photographs of H&E stained major organs including heart, liver, spleen, lung and kidney obtained from four groups after 18 days of treatment.\u2003The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Scientific Reportshttps://doi.org/10.1038/s41598-023-36363-2, published online 05 June 2023Retraction of: The Editors have retracted this Article.After publication, it was brought to the Editors\u2019 attention that the methods used to determine the sensitivity, specificity, and cut-off values presented in Table 5 are not described in sufficient detail to allow reproduction of the analyses. The Editors contacted the Authors to request clarifications and the raw data underlying the study. The Authors were not able to provide a clear and valid description of the methodology. They did provide some of the data; however, these were not the original raw data and the Editors were not able to confirm their veracity.The Editors therefore no longer have confidence in the results and conclusions presented in this Article.Khalid M. Mohany disagrees with the retraction. Mona A. H. El-Baz and Ahmed F. Amin did not respond to the correspondence about this retraction."}
{"text": "In \u201cThe Efficacy, Safety, and Efficiency of the Off-Label Use of Bevacizumab in Patients Diagnosed With Age-Related Macular Degeneration: Protocol for a Systematic Review and Meta-Analysis\u201d  the authors noted a missing Acknowledgments section. The Acknowledgments section has now been added to the published paper as follows:H&TRC authors gratefully acknowledge the FCT/MCTES national support through the UIDB/05608/2020 and UIDP/05608/2020.The correction will appear in the online version of the paper on the JMIR Publications website on July 4, 2023, together with the publication of this correction notice. Because this was made after submission to PubMed, PubMed Central, and other full-text repositories, the corrected article has also been resubmitted to those repositories."}
{"text": "This article has been corrected: The authors found that in Figure 6J the wrong images were used to illustrate migration of UM-UC-3 cells treated with si-circRGNEF+inhibitor or si-circRGNEF+KIF2C. The same error occurred in Figure 7I, where migration images of UM-UC-3 cells treated with negative control (NC) or T24 cells treated with mimic+KIF2C were incorrect. The authors corrected these errors with the images from the original sets of experiments, the same images used for the statistical analysis. The authors also found that the bar graph in Figure 7M, which should have represented statistical analysis data for UM-UC-3 cell invasion, was mistakenly replaced with duplicate UM-UC-3 migration data. The authors replaced the Figure 7M bar graph with the correct graph using the original data. These corrections do not change the content of the publication and do not affect the conclusions drawn from this research.Figures 6 and 7 are presented below.Corrected"}
{"text": "In the original publication , the figThe authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "The Publisher retracts the 14 August 2020 article cited above.Following publication, concerns were raised regarding the ownership and authorization of some of the data used in the study. Specifically, during the investigation, which was conducted in accordance with Frontiers\u2019 policies, the authors failed to provide authorization for the use of the nitrogen adsorption isotherm test data. The unauthorized data use was confirmed by an investigation led by the Ethics Committee of the CSIC (Consejo Superior de Investigatcciones Cient\u00edicas). This is a breach of Frontiers\u2019 guidelines and those of the Committee on Publication Ethics. As such, this article is being retracted.The authors do not agree to correspondence regarding this retraction.This retraction was approved by the Chief Editors of Frontiers in Chemistry and the Chief Executive Editor of Frontiers."}
{"text": "The corrected supplementary material can be found on the following pages. The authors would like to apologise for any inconvenience caused."}
{"text": "Following publication, the publisher uncovered evidence that a false identity was used in the peer-review process. The assignment of the false identity was confirmed by an investigation conducted in accordance with Frontiers' policies and the Committee on Publication Ethics (COPE) guidelines.Because the peer-review had been compromised, the investigation included a post-publication review of the article, which concluded that the article should have been rejected because it does not meet the standards for publication in Frontiers in Psychology.This retraction was approved by the Chief Editors of Frontiers in Psychology and the Chief Executive Editor of Frontiers. The authors do not agree to this retraction."}
{"text": "Cancer Cell International (2020) 20:28710.1186/s12935-020-01387-5The Editors-in-Chief have retracted this article. Concerns were raised regarding Fig.\u00a02d. This figure appears to overlap with Fig.\u00a04f in an article by different authors that was simultaneously under consideration with another journal . The EdiThe authors have not responded to correspondence regarding this retraction."}
{"text": "After having consulted the authors about these points, it was confirmed that there were certain aspects of the review that were in need of correction / clarification.This corrigendum therefore aims to rectify the problem of the incorrect factual information presented in this review, as follows (changes to the published text are highlighted in bold):3. Biochemistry of hemoglobin A1c\u201d on p. 2, line 7, the sentence starting here should have read as: \u201cIn the presence of glucose, glycan interacts with the amino group of Hb.\u201d;i) In the section \u201c2 group of the amino acid to form a Schiff base or aldimine,...\u201d;ii) In the same section, on line 10, the sentence starting here should have read as: \u201cThe first step is the reaction of the aldehyde group of glucose with the NHyielding HbA1c.\u201diii) In the same section, the sentence concluding on line 16 should have read as, \u201c... which contains a more stable and irreversible ketoamine bond, 4. HbA1c detection methods\u201d, towards the bottom of the left-hand column of p. 2, the first sentence in the second paragraph should have simply read: \u201cThe boronate affinity chromatography (BAC) method is often used as a reference method in several studies.\u201d ;iv) In the section \u201cDrugs\u201d in the right-hand column of p. 6), the authors wish to clarify that they were referring throughout to \u201cnon-enzymatic glycosylation , as was specifically stated in line 8 of this subsection.v) finally, where the term \u201cglycosylation\u201d was featured in this review (especially in the subsection \u201cExperimental and Therapeutic Medicine for granting them the opportunity to publish this; furthermore, they apologize to the readership for any misunderstandings or confusion caused.The authors thank the interested reader for bringing this matter to their attention. All the authors agree with the publication of this corrigendum, and are grateful to the Editor of"}
{"text": "In addition, certain of the data shown in the invasion assay experiments in Fig. 5C subsequently appeared in a more expansive form in the following paper, published by different authors at different research institutes: Wang H, Niu X, Jiang H, Mao F, Zhong B, Jiang X and Fu G: Long non-coding RNA DLX6-AS1 facilitates bladder cancer progression through modulating miR-195-5p/VEGFA signaling pathway. Aging 12: 16021\u201316034, 2020.Oncology Letters has decided that the paper should be retracted on account of an overall lack of confidence in the presented data. The Editor apologizes to the readership for any inconvenience caused.Although the authors did respond to our query and attempted to explain the issues associated with this problematic figure, the Editor of"}
{"text": "Correction to: Statistical Methods & Applications 10.1007/s10260-023-00690-5In the published version of the paper, two figures have been uploaded from a previous version. In view of that, the captions of Figs.\u00a0We report below Figs."}
{"text": "In the original publication the authors have discovered an error in the software algorithm used to calculate radial contribution to stroke volume (SV). The error consists of a failure to account for the slice gap when calculating septal movement and contribution to SV.Authors correcting note:Upon reviewing the algorithm used to calculate septal contribution to stroke volume an error was observed. The error consists of a failure to account for the slice gap when calculating septal movement and contribution to SV, affecting images with a slice gap of >\u20090 mm. After adjusting the algorithm the following changes are to be made in the manuscript:\u2212\u20092 ml [\u2212\u20093.8\u20132.1].Septal contribution to SV is -3.5 ml (-5.2\u20134.1) instead of Figure 5 has been revised. See revised Fig.\u00a05 attached.Figure 6 has been revised. See revised Fig.\u00a06 attached.In conclusion; after correctly taking slice gap into account, there is a minor change in the results as described above. However, the main conclusion of the study holds true."}
{"text": "Bioscience Reports at the request of the Editor-in-Chief and the Editorial Board following receipt of a notification from a reader, alerting the Editorial Board to cell-count distribution graphs that do not conform to the expected results for an experiment of this type.This article is being retracted from The authors were asked to provide the raw data in the form of the output from the flow cytometer, including the specific datapoints used to build the graphs. The authors provided the Editorial Board with PDF scatterplots but were unable to provide the specific data points, stating that this data was not saved. Given the lack of raw data, and that doubt remains over the validity of the graphs, the Editorial Board stands by the decision to retract. The authors agree to the retraction."}
{"text": "They also wish to apologize to the readership of the Journal for any inconvenience caused.After having re-examined their original data, the authors have realized that the data featured in"}
{"text": "Retraction Note:J Exp Clin Cancer Res37, 17 (2018)10.1186/s13046-018-0691-9The Editor-in-Chief has retracted this article. After publication, concerns were raised regarding highly similar images in the figures. Specifically:Figure\u00a01b shRNA CTR MHCC-97L image appears highly similar to Fig.\u00a06g shRNA CTR miR-185 inhibitor.Figure\u00a03a MHCC-97L ITGB5 blot image appears highly similar to Fig.\u00a03n WB: anti-Ub .Figure\u00a04h shRNA ITGB5 CTR image appears highly similar to Fig.\u00a06g shRNA ITGB5 miR-185 inhibitor.Figure\u00a04j shRNA ITGB5 and Fig.\u00a06i shRNA CRT miR-185 inhibitor images appear to overlap.Figure\u00a06j shRNA \u03b2-catenin CTR and shRNA ITGB5 miR-185 inhibitor images appear to overlap.The authors have stated that the images were misused, and provided the raw data for validation. However, due to the number and severity of concerns, the Editor-in-Chief no longer has confidence in the presented data.Zhikun Lin has stated on behalf of all co-authors they do not agree to this retraction."}
{"text": "Following publication, concerns were raised regarding the validity of the data in the article. Following provision of raw data by the authors, the Chief Editor concluded that the article\u2019s conclusions and assertions were not sufficiently supported by the findings from the material provided; therefore, the article has been retracted.This retraction was approved by the Chief Editor of Frontiers in Cellular and Developmental Biology and the Editor-in-Chief of Frontiers. The authors did not agree to this retraction."}
{"text": "PLoS Genet 11: e1005399, 2015.Following the publication of this paper, it was drawn to the Editor's attention by a concerned reader that lanes 1\u20133 of the EMSA results shown in Fig. 6 on p. 1278 were strikingly similar to data that had already appeared in a different form in the following publication by different authors at different research institutes: Qiu K, Li Z, Chen J, Wu S, Zhu X, Gao S, Gao J, Ren G and Zhou X: EIN3 and ORE1 accelerate degreening during ethylene-mediated leaf senescence by directly activating chlorophyll catabolic genes in Oncology Reports, the Editor has decided that this paper should be retracted from the Journal. After having been in contact with the authors, they accepted the decision to retract the paper. The Editor apologizes to the readership for any inconvenience caused.Owing to the fact that the contentious data in the above article had already been published prior to its submission to"}
{"text": "Nature Communications 10.1038/ncomms12884, published online 29 September 2016Correction to: 31P NMR chemical shifts of compounds 3 and 5, due to an instrument referencing error that has been recognized later. For compound 3, an incorrect 31P NMR chemical shifts value of 150.8 ppm was reported in the 3rd sentence of the 3rd paragraph of the Synthesis subsection of the Results, in the first entry of the second line of Table 1, and in the 6th sentence of the 4th paragraph of the Discussion; an incorrect value of 150.79 ppm was reported in the 12th sentence of the section \u2018Preparation of [Th(TrenTIPS)(PH)][Na(12C4)2] (3)\u2019 of the Methods . The correct version replaces 150.8 and 150.79 with 198.8. For compound 5, an incorrect 31P NMR chemical shifts value of 24.5 ppm was reported in the 4th sentence of the 4th paragraph of the Synthesis subsection of the Results, in the first entry of the third line of Table 1, and in the 6th sentence of the 4th paragraph of the Discussion; an incorrect value of 24.46 ppm was reported in the 14th sentence of the section \u2018Preparation of [{Th(TrenTIPS)}2(\u03bc-PH)] (5).\u2019 of the Methods. The correct version replaces 24.5 and 24.46 with 145.7. This has been corrected in both the PDF and HTML versions of the Article.The original version of this Article contained errors in the"}
{"text": "This is a correction of Biochem Med (Zagreb) 2023;33(2):020704. DOI: https://doi.org/10.11613/BM.2023.020704 Since the publication of the article, the authors have noticed that their first names and surnames in the by-line were listed in reverse. The correct by-line is presented above. We apologize to the authors for any inconvenience caused to the readers."}
{"text": "This article has been corrected at the request of the authors to edit data that had been mislabeled and transposed in the initial published version:Table 1: \u2018RTA\u2019 has been replaced with \u2018Fall from height\u2019 and \u2018Fall from height\u2019 has been replaced with \u2018RTA\u2019.Table 2: \u2018Anterior\u2019 has been replaced with \u2018Posterior\u2019 and \u2018Posterior\u2019 has been replaced with \u2018Anterior\u2019.Table 2 legend: \u201860.4% and 27.1%\u2019 has been replaced with \u201827.1% and 60.4%\u2019.Table 4 title: \u201875\u2019 has been changed to \u201852\u2019.Table 4: LUCL repair has been changed from \u201810 (19.2)\u2019 to \u201822 (44.0)\u2019.The authors deeply regret that these errors were not identified and addressed prior to publication."}
{"text": "Nanoscale paper due to anerror in Fig. 3c and 5b.The authors hereby wholly retract this In Fig. 3c the infrared thermal images of the mice in the control panel and theRT/PTT panel are identical.In Fig. 5b, kidney histology of 4 four treatment groups were compared. The imageused for the kidney RT/PTT panel was wrongly used and contains overlap with the kidneycontrol panel.We feel that these errors undermine the integrity of this study. We regret anyconfusion and apologize to the scientific community.Haifa Shen and Mauro Ferrari were contacted about this retraction but did notrespond to any correspondence. Signed: Min Zhou, Jun Zhao, Mei Tian, Shaoli Song, RuiZhang, Sanjay Gupta, Dongfeng Tan, Chun LiDate: 25/7/2023NanoscaleRetraction endorsed by Heather Montgomery, Managing Editor,"}
{"text": "This article has been corrected at the request of the authors to change the title from \u201cPre-transarterial Radioembolization of Tumoral Arteriovenous Fistula Associated With Recanalized Umbilical Vein Shunt in a Case of Hepatocellular Carcinoma With Hepatic Vein and Inferior Vena Cava Invasion\u201d to \u201cPretreatment Embolization of Tumoral Arteriovenous Fistula Associated With Recanalized Umbilical Vein Shunt in a Case of Hepatocellular Carcinoma With Hepatic Vein and Inferior Vena Cava Invasion\u201d.The authors and journal deeply regret that this error was not identified and addressed prior to publication."}
{"text": "The journal retracts the 11 August 2020 article cited above.Following publication, concerns were raised regarding the validity of the data in the article. The authors failed to provide the raw data or a satisfactory explanation during the investigation, which was conducted in accordance with Frontiers\u2019 policies. Given the concerns, and the lack of raw data, the editors no longer have confidence in the findings presented in the article.This retraction was approved by the Chief Editors of Frontiers of Physiology and the Chief Executive Editor of Frontiers. The authors have not responded to correspondence regarding this retraction."}
{"text": "This article has been corrected at the request of the authors due to an error that appears in Table 2 as well as the Materials and Methods: Study Design section. In both instances, the threshold\u00a0for defining compliance is incorrectly specified as 80%\u00a0instead of the\u00a0correct threshold of 60%. It is mentioned as 60-80% or 60% in both the Results and Conclusion sections, but should have been accurately depicted in Table 2 and the Materials and Methods section\u00a0as well. The authors and the journal regret that this error was not identified and addressed prior to publication."}
{"text": "Retraction Note: BMC Public Health 23, 638 (2023) https://doi.org/10.1186/s12889-023-15544-8The Editor has retracted this article because the authors had not obtained appropriate ethical approval before the recruitment of participants for this study began. None of the authors agree to this retraction."}
{"text": "New sequencing data of the iPSC line clearly indicates heterozygosity of the APP patient cells. The authors would like to apologize for not having identified this error earlier and any inconvenience caused. The error does not invalidate any of the data and conclusions previously reported. The text that requires emendation in light of this sequencing error is provided below."}
{"text": "After having been in contact with the authors, they agreed with the decision to retract the paper. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editor's attention by a concerned reader that the western blotting data shown in Fig. 5A and the cell migration and invasion assay data shown in Fig. 5C were strikingly similar to data appearing in different form in other articles by different authors at different research institutes, several of which have been retracted. Owing to the fact that the contentious data in the above article were already under consideration for publication, or had already been published, prior to its submission to"}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Owing to the fact that the contentious data in the above article had already been published prior to its submission to"}
{"text": "British Journal of Nutrition, the graphical abstract was erroneously omitted at the time of publication. The corresponding graphical abstract has now been added to the following articles and is present in their HTML version.In the below articles published in the Cambridge University Press apologises for this error."}
{"text": "The Editorial Office identified that the figures and data provided in the articles original submission were correct, and that this error was introduced by the authors during the first revision. The authors state that this occurred due to copying and pasting the graphs when checking the alignment of the graphs in The requested correction and related raw data have been assessed and agreed by the Editorial Board. The authors declare that these corrections do not change the results or conclusions of their paper."}
{"text": "There was an error in the original publication. We found that due to previous negligence, some important content was missing in the previous manuscript . It is aAppendix B:A correction has been made to Lemma\u00a0A1.: For any given continuous random variables\u00a0and\u00a0, if there is a bijection (one to one) mapping\u00a0and another random variable\u00a0such that for any\u00a0there is a\u00a0, and vice versa, where\u00a0denotes the domain of the variable\u00a0, then the mutual information between\u00a0and\u00a0is equal to the information between\u00a0and\u00a0, that is:Proof.\u00a0Because there is a one to one mapping And Equation (A17) can also be proved because of the commutativeness of the mutual information. \u25a1Due to the insertion of Lemma A1, the number of following Lemma are changed.The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "The authors wish to make the following corrections to this paper :In the original publication, there was a mistake in The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "This article has been retracted at the request of the authors. All authors consent to this retraction and together they have provided the following explanation:The members of the SAVE Program who were responsible for collecting and distributing the data used for Table 1 were not properly accredited. This also includes those involved in the execution of the program and the calling project. It is imperative that we maintain our integrity as members of the medical community, and allowing the article to remain accessible without properly crediting those essential to its creation would be an utmost violation of our values."}
{"text": "Open nephroureterectomy compared to laparoscopic in upper urinary tract urothelial carcinoma: a meta-analysis By Liu G, Yao Z, Chen G, Li Y and Liang B. (2021) Front. Surg. 8:729686. doi: 10.3389/fsurg.2021.729686A Retraction of the Systematic Review Article The journal and Chief Editors retract the 13 August 2021 article cited above.Following publication, concerns were raised regarding abnormal similarities with the contents of other articles published by unrelated research groups. A subsequent investigation, which was conducted in accordance with Frontiers' policies, raised strong concerns over the authorship of the articles, resulting in a loss of confidence in the findings presented in the article.The authors have not responded to this retraction.This retraction was approved by the Chief Editors of Frontiers in Surgery and the Chief Executive Editor of Frontiers."}
{"text": "After having been in contact with the authors, they agreed with the decision to retract the paper. The Editor apologizes to the readership for any inconvenience caused.Following the publication of the above paper, it was drawn to the Editors' attention by a concerned reader that various panels showing data from flow cytometric experiments in Figs. 2E, 5E and 6E, and the cell migration and invasion assay data shown in Fig. 2D and 6D, were strikingly similar to data appearing in different form in other articles by different authors. Owing to the fact that the contentious data in the above article were already under consideration for publication, or had already been published, elsewhere when it was submitted to"}
{"text": "BMC Complementary Medicine and Therapies (2022) 22:28810.1186/s12906-022-03765-0The Editor has retracted this article. The T2D\u2009+\u2009CD100 and T2d\u2009+\u2009CD150 panels in Fig.\u00a02a appear to partially overlap. The authors have provided the original images upon request; however, these images also appear to overlap.Additionally, the NC\u2009+\u2009veh, T2D\u2009+\u2009veh and T2D\u2009+\u2009DON images and data in Fig.\u00a02 appear highly similar to the same groups in Fig.\u00a02 of the authors\u2019 earlier article .The Editor therefore no longer has confidence in the reliability of the data and conclusions reported in this article.Adel A. Gomaa, Hanan S. M. Farghaly and Mariam A. Nicola do not agree to this retraction. Rania M. Makboul and Abeer M. Hussien have not responded to any correspondence from the Editor about this retraction."}
{"text": "After publication, we noticed a minor error in"}
{"text": "This is a peer-review report submitted for the paper \u201cTechnologies to Support Assessment of Movement During Video Consultations: Exploratory Study.\u201dThe paper  is well The title is chosen correctly, and the abstract provides sufficient information to give a clear idea of what to expect from the paper.The results are well highlighted, and the conclusions are adequate.The technical depth of the paper meets the requirements for a scientific article published in a quality journal."}
{"text": "Retraction Note: Alz Res Ther 13, 37 (2021)https://doi.org/10.1186/s13195-021-00769-9Fig. 3b 5xFAD\u2009+\u2009Veh CAI 12-month-old group image appears highly similar to an image representing the same group in [In Fig. 3B, 5xFAD\u2009+\u2009SCLP Cortex and Entorhinal cortex images appear to originate from the same sample.In Fig. 3E, the beta-tubulin blots presented for the cortex 6- and 12-month-old groups appear highly similar; the beta-tubulin blot image for hippocampus in the 6-month-old group appears highly similar to that representing beta-tubulin in the 12-month-old group in Figs. 5F and 7A.The updated Fig.\u00a04G 5xFAD Primary 6-month-old group image appears to overlap with Fig.\u00a04I 5xFAD Secondary 12-month-old group.The top beta-tubulin blot in Fig.\u00a06F appears highly similar to the beta-tubulin (hippocampus) blot in Fig.\u00a07A.The blots in Fig. S2I appear highly similar to those in Fig.\u00a03D of [Fig. S5A appears highly similar to the Merged 5xFAR\u2009+\u2009SLCP (2d) image in Fig.\u00a01B of [The Editors-in-Chief have retracted this article at the authors' request. After publication, concerns were raised regarding a number of cases of image overlap within the Figures, which the authors addressed by a Correction . HoweverDespite internal data validation, the authors no longer have sufficient confidence in the findings of this study.All authors agree to this retraction."}
{"text": "Fig.\u00a0S3. PTH (1-34) attunes the KOA progression by restoring cartilage thickness and retaining GAG content from (a) Alican Blue staining and (b) Masson staining.\u201d in Appendix A. Supplementary data in our published paper. We found an error of DMM OPG-/- mice at the 8th week and the 12th week in Alican Blue staining. We now have corrected the Fig.\u00a0S3 and used the right histology evaluation (DMM OPG-/- mice at the 12th week). Of note that, the correction of the Fig.\u00a0S3 would have no influence on the conclusion of the current study.The authors regret \u201can error occurred in the The authors would like to apologise for any inconvenience caused.Fig.\u00a01) for Appendix A. Supplementary data Fig.\u00a0S3. An error occurred in the DMM OPG-/-mice at the 8th week and the 12th week.Here is the original published one  for Appendix A. Supplementary data Fig.\u00a0S3. We used the corrected histology evaluation (DMM OPG-/-mice at the 12thweek) in Alican Blue staining.Here is the amended figure ("}
{"text": "Retraction Note: BMC Complement Med Ther 4, 315 (2015)10.1186/s40064-015-1059-7The Editor has retracted this article. Concerns were raised about a number of the images presented in Figs.\u00a02, 10 and 11. The authors provided raw data; however, as there were inconsistencies in these data the Editor no longer has confidence in the results and conclusions presented. In addition, the authors have not provided evidence of appropriate ethical oversight of this study. Vikas Kumar disagrees with this retraction. Danish Ahmed, Amita Verma, Girja Shankar Shukla and Manju Sharma have not responded to correspondence from the Editor about this retraction."}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a satisfactory reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editor's attention by a concerned reader that the colony formation assay data shown in Fig. 3A on p. 3399 were strikingly similar to data that were already under consideration for publication in another article written by different authors at different research institutes. Owing to the fact that the contentious data in the above article were already under consideration for publication prior to its submission to"}
{"text": "Scientific Reports 10.1038/s41598-022-08134-y, published online 12 March 2022Retraction of: The Editors have retracted this article.After publication concerns were raised that the XRD spectra in Figure\u00a013 are identical. The authors are unable to provide the original data for examination. In addition, an investigation by the Editors has shown inappropriate changes in authorship during the review process. The Editors no longer have confidence in the results and conclusions presented.Jawad Ahmad, Amjad Ali Pasha and Kashif Irshad disagree with this retraction. Amjad Ali Pasha has stated on behalf of Mostefa Bourchak that they disagree with this retraction. The Editors were not able to obtain a current email address for Rebeca Martinez-Garcia and Jes\u00fas de-Prado-Gil."}
{"text": "Correction to: International Microbiologyhttps://doi.org/10.1007/s10123-023-00332-6The authors regret that an unnecessary sentence* was embedded at the beginning of the \u201cResults and discussion\u201d section.* \u201cWe refer to 3 different parameters:(i) microbial ecology of the environment.(ii) nutritional habits.(iii) social habits\u201dThe original article has been corrected.\u00a0The authors apologize for any inconvenience caused."}
{"text": "In the original publication by Khan et al., 2022 , there wThe authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors\u2019 attention by a concerned reader that certain of the data shown for the flow cytometric assay experiments in Figs. 2E and 5E were strikingly similar to data appearing in different form in other articles by different authors. Owing to the fact that the contentious data in the above article had already been published elsewhere, or were already under consideration for publication, prior to its submission to"}
{"text": "To the Editor:Rambam Maimonides Medical Journal, Ashkenazi and Olsha examined the association between the prevalence of misattributed authorship and trust in the institution analyzing misconduct in their scholarly publications.3In their article \u201cAuthorship Disputes in Scholarly Biomedical Publications and Trust in the Research Institution\u201d in the July 2023 issue of For a time, I collected two types of articles displaying exaggerated authorship: (1) papers in which the number of authors exceeded the number of patients studied, usually in a small clinical trial; and (2) reports of single cases in which the authorship consisted of ten or more authors.4The ingenuity and creativity of justifying authorship in the cases in which the journal required such an explanation impressed me. In recognition of those skills, I have offered the Marshall A. Lichtman Prize to the senior author.Initially Kovacs, and then I, have provided, independently, a solution to the disturbing trend of inappropriate \u201cgift\u201d or \u201chonorary\u201d authorship.The law of conservation of mass requires the mass of the products to be equal to the mass of the reactants. Under our suggested new system, the number of citations would not exceed the number of papers. It is inappropriate, indeed misleading, to generate multiple papers from one paper, as the current citation process does; and, it fosters the practice of adding undeserving authors. There is no cost to the appropriate authors to add any number of undeserving authors in an act of collegiality or a group effort to inflate citations,3Kovacs has provided the most in-depth discussion of the pros and cons of the proposal to have the citation credit of all authors on a paper sum to one paper."}
{"text": "The graphs had been switched with those in Figure S1. The corrected \u201cFigure 4. Screening for protein\u2013protein interactions between FMDV 3Dpol and the sixteen selected IFN pathway proteins from the cattle, sheep, goat and swine libraries.\u201d version appears below. The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated.In the original publication , there w"}
{"text": "Retraction Note: BMC Complement Med Ther 17, 326 (2017)10.1186/s12906-017-1830-0The Editor has retracted this article. After publication it was noted that in Fig.\u00a06 there is overlap in Fig.\u00a06A between the CA1 Model and XYS images and also in Fig.\u00a06B between the CA1 Control and XYS images. The authors were asked to provide the raw data for the figure, however, the data provided by the authors could not be matched to the data used in the figure. The Editor has therefore lost confidence in the integrity of the data presented in this article.None of the authors agree to this retraction."}
{"text": "Retraction Note: Italian Journal of Pediatrics (2022) 48:9410.1186/s13052-022-01247-0The Editor-in-Chief has retracted this article at the request of the corresponding author Dong Li because the authors have become aware of a number of errors in the data presented. Dong Li agrees with this retraction. Jin-Yue Huang, Wen-Xuan Fan, Jing Meng and Chun-Quan Cai have not responded to correspondence from the Publisher about this retraction."}
{"text": "Rajeswari et al., RSC Adv., 2014, 4, 61525\u201361536. https://doi.org/10.1039/C4RA12207K.Retraction of \u2018Investigation of anticorrosive, antibacterial and  RSC Advances article due to concerns with the reliability of the data in the published article.The Royal Society of Chemistry, with the agreement of the authors, hereby wholly retracts this The HRSEM image in Fig. 4c represents a scaled version of part of the image presented in Fig. 4e. However, both images are presented with the same scale bar and represent different samples.Repeating fragments can be observed in the images in Fig. 6a\u2013f, indicating that the images have been manipulated.The optical images in Fig. 8a\u2013c have been duplicated in other publications. The panel in Fig. 8a has been duplicated as Fig. 9a in ref. The authors informed the editor that the characterization of the original samples was outsourced, and they do not have the original raw data for the published results.Given the significance of the concerns about the validity of the data, and the lack of raw data, the findings presented in this paper are not reliable.Signed: D. Rajeswari, D. Gopi, S. Ramya and L. KavithaDate: 16th March 2023RSC AdvancesRetraction endorsed by Laura Fisher, Executive Editor,"}
{"text": "Considering the nature of the concerns in this case, the article contents were removed from the journal\u2019s website at the time of retraction.This issue has not been resolved following discussions between PLOS and the authors. Therefore, the The authors did not reply or could not be reached to comment on the retraction decision.\u00ae-8 scale (used in this study) was originally published in 2008 [\u00ae trademark was also registered by Donald E. Morisky on January 29, 2019 (Reg. No. 5837374). Any reference to \u201cMMAS\u201d in this article [Note: the MMAS"}
{"text": "Retraction Note: BMC Cancer 20, 681 (2020)https://doi.org/10.1186/s12885-020-07167-8The Editor has retracted this article. After publication, concerns were raised regarding highly similar images in Fig.\u00a02a , which the authors addressed by a Correction. However, further concerns have been identified by the publisher, specifically:Fig. 3c and 3i 0h and 24h control images appear to be the same.Fig. 3c 50 and 100 uM group 0h images appear highly similar The authors have also found three other misused images in Fig. 3c (NSC23766 50 \u00b5M 0h) and i (ML141 20 \u00b5M and 40 \u00b5M 0h), and incorrect errors bars in the data presented in Fig.\u00a04a.The Editor therefore no longer has confidence in the presented data.All authors agree to this retraction."}
{"text": "Retraction Note: BMC Complementary Medicine and Therapies (2020) 20:19410.1186/s12906-020-02980-xThe Editor has retracted this article. After publication, concerns were raised regarding a number of figures in this article. Specifically:In Fig.\u00a02B, the H1975 and A549 cell images in the 100\u00a0mg/l treatment group appear to originate from the same sample with different magnification.In Fig.\u00a05A, the A549 PCNA western blot image appears highly similar to the NLRP3 blot in Fig.\u00a07C.In Fig. S2B, the H1975\u2009+\u2009Beclin-1-Si-3 DMSO image appears to originate from the same sample as Fig.\u00a02B A549 50\u00a0mg/l treatment group with different magnification.The authors have provided the raw data to address these concerns. However, the raw data files contained further image overlap. The Editor therefore no longer has confidence in the presented data.All authors agree to this retraction."}
{"text": "Ginger is an herbaceous and flowering plant renowned for its rhizome, which is widely employed as both a spice and an herb. Since ancient times, ginger has been consumed in folk medicine and traditional cuisines for its favorable health effects. Different in vitro and in vivo studies have disclosed the advantageous physiological aspects of ginger, primarily due to its antioxidant, anti-inflammatory, antimicrobial, and anti-carcinogenic properties. These health-promoting features are linked to the variety of bioactive compounds that are present in ginger. Following the advancement in consumer awareness and the industrial demand for organic antioxidants and functional ingredients, the application of ginger and its derivatives has been broadly investigated in a wide range of food products. The prominent features transmitted by ginger into different food areas are antioxidant and nutraceutical values (bakery); flavor, acceptability, and techno-functional characteristics (dairy); hedonic and antimicrobial properties (beverages); oxidative stability, tenderization, and sensorial attributes (meat); and shelf life and sensorial properties . This review is focused on providing a comprehensive overview of the tendencies in the application of ginger and its derivatives in the food industry and concurrently briefly discusses the beneficial aspects and processing of ginger. Zingiber officinale Roscoe) plant, producing an irregular bumpy rhizome, is extensively cultivated in the southeast region of Asia. Accurate information regarding ginger plant\u2019s origin is not available due to a very long cultivation history in this region. In ancient Greek history (40\u201390 AD), the Greeks were familiar to the dietary and culinary uses of ginger. In the 13th century, during his visit to China and Sumatra, Marco Polo became acquainted with ginger and imported it to Europe. In the same era, the Arabs transported the ginger from India to East Africa, while the Portuguese spread it to West Africa . Fo. Fo27]. Gingerols are sensitive to some processing and storage conditions like thermal processing, acidic environments, air, light, and prolonged storage. When gingerols undergo these conditions, there is a possibility of the transformation of gingerols into shogaols . StudiesThe chemical composition and yield of ginger extract and ginger essential oil are also influenced by the extraction method. Advanced and green extraction techniques are preferred over classical extraction techniques . The extFurthermore, a synergistic effect with a superior quality product could also be achieved through the consolidation of these extraction techniques, and this is the most emerging approach in the field of extraction to maximize the extraction efficiency through the synchronization of two or more advanced extraction technologies . For insAs mentioned above, the functional and bioactive compounds present in ginger are associated with multiple health benefits and advantageous characteristics. The exploitation and characterization of the versatile biological and functional competencies of ginger are also crucial for further research. These multifaceted bioactivities of ginger bioactives and their modes of action are discussed here in this section.Any disturbance or adjustment with the cell\u2019s antioxidant defense system can lead to the excessive production of Reactive Oxygen Species (ROS), and eventually, to an increase in oxidative stress. For the recovery of normal levels of free radicals and oxidative stress, various natural antioxidants have been analyzed for the neutralization of free radicals and encounter oxidative stress for the prevention of different health disorders . The maiIn the past two decades, the exploration of natural plant resources has become very attractive and beneficial, most probably due to the presence of bioactives, less toxicity, and the lower production costs . Ginger Inflammation is a phase in the natural healing process of the body to combat intruders for the prevention of infection or injury. The basic aim of inflammation is to abrogate cellular damage, withdraw and absorb necrotic cells and tissues, and regain the stability and conformity of the intracellular environment . When ceIt was also observed that the anti-neuroinflammatory capacity of gingerols enhanced with the increase in the alkyl chain length as 10-gingerol\u2019s anti-neuroinflammatory activity was higher than the other active compounds of ginger . FurtherPsedomonas aeruginosa (a multi-drug-resistant strain) by disturbing the membrane stability and preventing biofilm formation. Currently, chemical and synthetic antimicrobials are being replaced with natural and organic antimicrobials derived from plants, animals, and microorganisms, both in health management and in food preservation. These biologically derived antimicrobials from plant sources are preferred due to their multi-oriental management, multi-targeted approach, drug resistance, and lower toxicity . Ginger Escherichia coli and Staphylococcus aureus. A study reported the bactericidal mechanism of ginger essential oil through the demolishment of the cell membrane activity and through intervening with the energy metabolism because of some macromolecular elements like proteins and nucleic acids [Candida, Aspergillus niger, and P. aeruginosa and a mild effect against Saccharomyces cerevisiae, and no inhibition was detected against Bacillus subtilis, Trichoderma spp., and Pencillium spp. Ginger oil obtained from dried ginger was observed to have higher anti-bacterial activity against P. aeruginosa [Ginger essential oil possesses excellent anti-bacterial activity against food-borne pathogenic bacteria such as ic acids . Anotherruginosa . There iruginosa .Cancer is one of the major causes of death in the world, and in 2020, approximately 19 million cancer cases were reported, out of which about 10 million cases worldwide were fatal . In receIn vivo and in vitro studies were carried out to evaluate the action mechanism and cytotoxic effects of ginger against prostate cancer . It was There is a possibility of an onset of neurodegenerative diseases such as Alzheimer\u2019s disease and Parkinson\u2019s disease, and old people are at an especially high risk. Many recent studies have expressed that ginger possesses anti-neuroinflammatory capacity and has a significant role in memory function, which might be useful in the management and inhibition of neurodegenerative diseases ,63. It wWorldwide, the dominant cause of premature deaths (17.9 million people per year) is cardiovascular disease . VariousObesity or overweight is a great concern throughout the world, and it emerges from the disturbance in the energy metabolism. Basically, there are two types of adipose (fat) tissues classified on the basis of their arrangements and activities. The core function of white adipose tissues is to serve as energy depositories, while brown adipose tissues are responsible for metabolism improvement and energy expenditure. The transformation of white adipose tissues to brown adipose tissues is a novel approach to tackle obesity. 6-Gingerol could stimulate the cell browning via an AMPK-dependent approach in 3T3-L1 adipocytes ,69. GingDiabetes mellitus is a chronic metabolic disease characterized by the insufficiency of insulin and/or insulin resistance, resulting in an uncontrolled increase in the blood glucose level. Persistent hyperglycemia could promote protein glycation and the generation of advanced glycation end products (AGEs). An in vitro study revealed that 6-gingerol and 6-shogaol inhibited the proliferation of diabetic complexities and confined the methylglycoxal (MGO), the precursor of AGEs, to hinder AGE production . The oraCurrently, there is a growing trend towards healthier and functional food products as consumers are more conscious about healthy lifestyles and daily intakes. Due to prospering recognition and interest in functional food products, the scope for the exploration, characterization, and potential utilization of functional food ingredients and bioactive compounds has also magnified. Ginger, being a valuable functional ingredient and marvelous source of bioactives, has also been integrated into a variety of food products. Here, the food applications of ginger in its different forms  will be discussed to provide a comprehensive and broader prospective of its employment. The impact of ginger incorporation on the sensorial attributes of various food products is also discussed below .Rhizopus stolonifer on bread, but ginger may impart unfavorable flavor characteristics to the bread [A variety of studies have been carried out to use ginger as a potential food additive in bakery products . For inshe bread . The aforementioned studies mainly dealt with the addition of ginger to produce functional bread. However, in some parts of the world, distinct baking products exist wherein ginger is used as a dominant flavoring ingredient. For instance, gingerbread is a traditional bakery product in the Czech Republic, particularly in the town of Pardubice, where ginger is the prevalent flavor. It is produced in a variety of shapes, types, and textures ranging from a crispy biscuit to a soft cake ,80. HencLee et al.  proposedThe functional, nutritional, antioxidant, and sensorial properties of millet flour and ginger powder-formulated cookies were investigated by Marak et al. . This stTo a large extent, Almasodi  successfAs per the foregoing studies, ginger powder is the most widely employed form of ginger in bakery products, followed by ginger juice. The pertinent amount of ginger powder and processing conditions are the key factors in the acquirement of balanced functional bakery items without any alteration in the desirable characteristics of the product. So, bakery products with admirable nutraceutical values could also be produced through the precise supplementation of ginger. There is also a considerable potential for innovation and improvement in the dairy sector, where ginger, an active ingredient, has also contributed . The supA novel approach was also attempted to evaluate the effects of ginger, cinnamon, and carob powders on spray-dried milk powders and their agglomerates . Milk pov/v) was regarded as the suitable concentration in yogurt production [Apart from ginger powder, the effect of ginger juice on the physicochemical and hedonic attributes of yogurt was also investigated at different concentrations. An inverse relationship was observed among the amount of ginger juice, the viability of the starter culture, and the hardness of the product. Based on the finding of this study and the sensorial characteristics of the product, the ginger juice addition at the rate of 4% . The increase in the ginger juice concentration was inversely proportional to the fat, protein, and total solid contents of the product. Considering the sensorial properties and other attributes, a 2.5% ginger juice addition in the milkshake was regarded as an optimum value. Gaur et al. [Jadhav et al.  formulatr et al.  also sucw/w) with a better hedonic response than all other treatments including the control. Ginger juice improved the product\u2019s resistance against melting but lowered the fat and total solid contents in the herbal ice cream [L. acidophilus-based probiotic culture to produce probiotic ice cream at the optimized levels of 3%, 6%, and 7% (w/w), respectively.Several studies were also designed for the potential exploitation of ginger into an herbal ice cream product. Herbal ice cream could be manufactured employing 4% ginger juice  and goat milk was characterized with the highest antioxidant activity than other milk sources . A sensorial analysis revealed that herbal yogurt augmented with ginger extract (1%) was superior in color and appearance, while garlic extract (0.2%) was responsible for a better taste and flavor ,107.Ginger extract in combination with gum arabic has also been exploited in the manufacturing of a yogurt-based traditional Iranian drink, Doogh . The synThe ethical, economical, and supply chain aspects of the calf rennet compelled dairy experts to explore other potential sources of milk coagulation. Ginger and its derivatives were also analyzed as potential coagulants in cheese processing. Ginger crude extract emerged as an auspicious coagulant in soft un-ripened cheese manufactured from camel milk . Ginger Ginger extract has been productively employed in soft cheese manufacturing as a functional ingredient. Ginger extract addition promoted the quality attributes of soft cheese by reducing the pH, oxidative rancidity, and microbial load while increasing the proteolysis, cohesiveness, and smoothness of the product. Ginger extract-fortified cheese also earned higher scores for texture, flavor, and overall acceptability than the control. Ginger extract (4%) coupled with the pickling of the soft cheese was reported with superior quality characteristics . Herbal ice cream with health-promoting attributes and a reduced sugar content could also be prepared by formulating ginger extract and xylitol . The phyIn another study, different forms of ginger such as ginger juice, paste, candy, and powder were formulated into ice cream to analyze its physicochemical and hedonic attributes. The addition of ginger juice and paste decreased the fat, total solid, and overrun contents, while the incorporation of ginger candy and powder increased the fat, total solid, and overrun contents, but the phenolic contents and antioxidant capacity were increased in all inclusions. The product\u2019s resistance to melting improved in all preparations of the ginger, and the optimized incorporation level of all ginger forms were 4% paste, 6% juice, 10% candy, and 1% powder . A novel approach of utilizing ginger essential oil in yogurt preparation was also successfully applied to evaluate the quality characteristics of the final product. Ginger essential oil enrichment (1000 ppm) lowered the syneresis and pH, while it enhanced the shelf life of the product and improved the overall acceptance of the product . EffortsIn conclusion, ginger\u2019s diversified applications in dairy products have demonstrated its vast potential as a functional ingredient. Among the different forms of ginger, ginger extract came up as an extensively employed form, followed by ginger juice, powder, and essential oil. Ginger extract exhibited its aptitude for improving the overall techno-functional characteristics of dairy products and offering persuasive coagulation properties for cheese manufacturing. While the use of all forms of ginger proved to be effective in elevating the functionality and efficacy of dairy products, at the same time, some quality and hedonic characteristics were also compromised, but the incorporation of ginger extract was identified with higher functional and physicochemical improvements and minimal quality defects.Like other food sectors, the incorporation of functional food ingredients including ginger has also been investigated in beverages . In the Ginger extract in combination with lemon juice rendered an excellent job as a natural preservative in a carrot\u2013mandarin RTS drink. During storage, a few modifications were observed in the physicochemical properties, but the product characteristics remained consistent to a large extent . A gingeFresh ginger extract was adequately exploited in the production of a ginger-based functional carbonated beverage. The functionality and sensorial characteristics of the drink were improved with the addition of ginger rhizome extract, but the shelf life was largely associated with the carbonation level of the product . In anotHibiscus sabdariffa flowers [Ginger is also a vital ingredient in Zobo drink, a traditional and indigenous Nigerian drink prepared from  flowers . The for flowers . v/v) was furnished for a functional beverage utilizing ginger extract (15.1%), tamarind extract (9.9%), turmeric extract (5.0%), sugar solution (40%), and water (30%). Ginger has also been formulated in various functional beverages in the form of blends with different spices, herbs, fruits, and other food ingredients. A soybean, ginger, and mango-based functional drink was developed to effectively exploit the nutritional and functional values of these ingredients, which were consequently attributed with feasible sensorial properties and overall acceptability . An optiGinger extract, Kencur extract, and their combination blend were incorporated into an instant temulawak beverage, an indigenous Indonesian drink, to evaluate their impacts on the physicochemical and sensorial attributes of the final product. The inclusion of ginger extract in a concentration of up to 15% enhanced the flavor, aroma, and overall acceptance of the Temulawak drink . AnotherThe integration of two different food ingredients could ameliorate the defective quality attributes of the intended food product. The fusion of a better coloring feature from tea and a favorable flavoring attribute from ginger resulted in a superior acceptable beverage product . During The above-mentioned research findings have provided insight into the exploitation of ginger in beverage products. Even in beverages, the employment of ginger extract seems to dominate over the rest of the ginger derivatives due to its better assimilation and conducive characteristics. The incorporation of ginger into different drinks not only augmented but also maintained the shelf life, nutraceutical value, and antimicrobial activity. Several investigations and experiments were also conducted to figure out the effects of ginger and its derivatives in various forms on meat and fish products . Rabbit A comparative analysis was conducted to assess the effects of three different spices as potential organic preservatives in raw chicken meat products. Clove powder (0.2%), even in a very small quantity, compared to ginger (3%) and garlic (2%) pastes performed very well to improve the oxidative stability, physicochemical properties, and antimicrobial activities in raw chicken meat with refrigerated storage . Ginger It was revealed that the competence level of ginger was as good as sodium ascorbate to combat oxidative rancidity, while the textural and sensorial properties of meat products with ginger were better than synthetic antioxidants . Ginger Smoked mackerel fish was treated with ginger extract to evaluate its influence on the shelf life and hedonic characteristics . Ginger A variety of synthetic tenderizers and proteolytic enzymes had been engaged in the tenderization of meat. Currently, natural tenderizers are in demand due to certain constraints of synthetic tenderizers such as safety issues, unpleasant tastes, and over-tenderization. Ginger extract (5%) was recommended as a potential tenderizer for Yak meat as it enhanced the cooking yield, tenderness, and lipid oxidative stability during storage ,150. Researchers had also adopted a distinct approach to improve the meat quality through feeding ginger, as a potential dietary supplement, to the animals. Ginger and its derivatives in various forms were highly effective in inducing favorable characteristics such as lowering the cholesterol and improving the egg functionality and carcass quality in poultry animals ,152. TheAs per the aforementioned studies, ginger has an extensive application potential in the meat industry, embellishing meat products with an array of favorable characteristics. The incorporation of ginger into meat products competently ameliorated the nutritional value, oxidative stability, lipid profile, and antimicrobial activity of the meat products. The ability of ginger to provide elegant antioxidant and tenderization activities without compromising the sensorial and textural attributes of meat products has also provided another priority lead over artificial antioxidants and tenderizing agents. The inclusion of ginger in the diets of animals as a dietary supplement has also emerged as a novel and efficient approach, which remarkably improves the fatty acid profile and carcass quality of the animals.Ginger and its bioactive compounds have also been examined for their potential applications as edible coatings, films, or active ingredients in packaging . The usev/v) ginger essential oil, regarded as whey protein isolate ginger (WPIG) coating [E. coli and S. aureus, while Tsironi et al. [Whey protein isolate (WPI) coating on Kashar cheese was characterized with water and fat barrier attributes, which were significantly developed with the addition of 1.5%  coating enhanced the shelf life and maintained the quality attributes of beef; moreover, these characteristics were substantially improved with the incorporation of ginger essential oil (SAG) into edible coating . CompareFish sarcoplasmic protein and chitosan composite films enriched with ginger essential oil (up to 3%) were analyzed for their physicochemical and antioxidant features . Ginger Zhang et al.  also forIt is evident from the foregoing literature that ginger oleoresins have promising applications in edible films, coatings, and the packaging sector, where ginger essential oil has better and extensive utilizations than ginger extract. The consolidation of ginger significantly improved the oxidative stabilities, antimicrobial activities, and sensorial properties of the intended food products. Ginger also performed better than the synthetic preservatives, improved the shelf life, and retained the quality attributes of the products.Ginger, with strong antioxidant, antimicrobial, and other functional activities, has a great potential for employment in the food industry. In this review, many studies have been presented regarding the acquirement of the bioactive compounds of ginger in different forms such as powder, extract, juice, paste, and essential oil. The application of ginger and its derivatives in a variety of food products has been extensively investigated and reported with auspicious results. Among all of the derivatives of ginger, ginger extract was found to be a more practicable, efficient, and versatile form of ginger for food applications. Ginger essential oil is another efficient variant of ginger, but its food applications are limited because of its strong aroma and immiscibility with certain food products.These studies have also revealed another positive aspect of ginger, which is that it could be employed in a wide range of food products, covering almost all leading sectors of the food industry. The incorporation of ginger, in its various forms, thoroughly improved the functionality and bioactivity of the intended food products, but the physicochemical and sensory properties of these products were also compromised in a legitimate number of studies. Further studies mainly focused on the efficacy, optimization, and assimilation of ginger bioactives into food products without compromising the physicochemical characteristics and sensory profiles of the products must be carried out. The probable synergistic effect of ginger bioactives with other compounds and toxicity studies of different compounds in their purest forms should also be investigated to ensure the safe use of these functional compounds."}
{"text": "The authors were not able to provide the raw data and the Editor-in-Chief and editorial board no longer have confidence in the reported results. The article is therefore retracted.Materials.This retraction was approved by the Editor-in-Chief of the journal The authors did not agree to this retraction."}
{"text": "Applied Bionics and Biomechanics has retracted the article titled \u201cTo Explore the Effects of Acupuncture and Medical Treatment at Different Times on the Gastrointestinal Reaction and White Blood Cell Count of Patients with Lung Cancer Chemotherapy\u201d [therapy\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifiThe authors do not agree to the retraction."}
{"text": "During the final proofreading step of this paper , some er3 in author name part should also be changed to Victoria Cirone 3,4,5.The original Affiliation 3 should be changed to Affiliations 3, 4 and 5. Victoria Cirone Original Affiliation 3: Department of Physical Therapy, Djavad Mowafaghian Centre for Brain Health, Vancouver Coastal Health Research Institute, The Centre for Aging SMART, The University of British Columbia, Vancouver, BC V1Y 1T3, Canada.After changed: Affiliation 3: Department of Physical Therapy, Faculty of Medicine, University of British Columbia, Vancouver, BC V6T 1Z3, Canada.Affiliation 4: Djavad Mowafaghian Centre for Brain Health, Vancouver Coastal Health Research Institute, Vancouver, BC V6T 1Z3, Canada.Affiliation 5: Centre for Aging SMART at Vancouver Coastal Health, Vancouver Coastal Health Research Institute, Vancouver, BC V5Z 1M9, Canada.DV2RbSE b95% CIspIn the original publication, there was a formatting error in Table 3 as published. In the first row of identifying variables, it should be updated from Cis to CIs . The correction appears below. The authors state that the scientific conclusions are unaffected.There were minor typographical errors in the original publication. Below is the list of minor amendments. The authors state that the scientific conclusions are unaffected.TYPO: Section 2. Methods; 2.1. Participants: please update \u201crecruited to complete this study (May 2020\u2013February 2022) and they...\u201d from May 2020 to May 2021.CORRECTION: Adults between 18 and 35 years old were recruited to complete this study (May 2021\u2013February 2022) and they received monetary compensation.2.TYPO: Section 2. Methods; 2.2. Materials; 2.2.2. Estimated Cardiorespiratory Fitness: please update \u201cThe six-minute walk test (6MWT) is a tool used to measure the distance an individual can walk on a straight path in six-minutes\u201d by removing the dash from the six minutes at the end of the sentence. It should read: \u201cThe six-minute walk test (6MWT) is a tool used to measure the distance an individual can walk on a straight path in six minutes\u201d.CORRECTION: The six-minute walk test (6MWT) is a tool used to measure the distance an individual can walk on a straight path in six minutes .3.TYPO: Section 2. Methods; 2.6. Operation Span (OSPAN) Task: please update \u201cwith a three by four matrix of letters\u201d to \u201cwith a three-by-four matrix of letters\u201d.CORRECTION: Finally, participants were presented with a three-by-four matrix of letters and had to select the letters in sequence as they had appeared prior to the math task.4.TYPO: Section 4. Discussion (paragraph 2): There is a missing period after reference 92.CORRECTION: That said, the effect sizes tend to be larger in children than in adults [92].The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "Upon re-conducting the crucial experiments, they found that the trend of CD133 as depicted in Figure 1C did not align with the results initially reported in the manuscript.In their statement, the authors noted: \u201cAfter the loss of some original data, we repeated the experiments and discovered discrepancies when grouping by age; the trend of CD133 in Figure 1C did not replicate the results in the original text (see attachment). Subsequent experiments could not validate the original conclusion that the concentration of CD133+ in renal stem cells peaks in the neonatal group and decreases with age. As a result, we acknowledge there are inaccuracies in the scientific content of the study. To prevent any potential confusion or misinterpretation among readers and to maintain the credibility of the journal, we request a retraction in line with the journal\u02bcs policy.\u201dAcknowledging the authors\u02bc transparency, and in adherence with our journal\u02bcs retraction policy, the decision to retract the paper was made. We regret any misunderstanding or inconvenience this may have caused to our readers. We commend the authors for their dedication to scientific precision and their responsible approach to this issue.Biomolecules and Biomedicine remains firmly committed to upholding the highest standards of research integrity. We assure the readers that we will continue to take all necessary steps to rectify the scientific record when warranted."}
{"text": "The journal retracts the 2022 article cited above.Following publication, concerns were raised regarding the provenance of the patient data used in this study. Specifically, during the investigation, which was conducted in accordance with Frontiers' policies, it was found that the authors failed to provide appropriate authorization for the use of patient data. Unauthorized data use is a breach of Frontiers' guidelines and those of the Committee on Publication Ethics. As such, this article is being retracted.This retraction was approved by the Chief Editors of Frontiers in Medicine and the Chief Executive Editor of Frontiers. The authors agree to this retraction."}
{"text": "Following publication, concerns were raised regarding the integrity of the images in the published figures. Specifically, image duplication concerns were identified in Figure 7E. The authors failed to provide a satisfactory explanation during the investigation, which was conducted in accordance with Frontiers' policies. As a result, the data and conclusions of the article have been deemed unreliable and the article has been retracted. The authors agree to this retraction."}
{"text": "Following the publication of this article , 2, concIn Figure 3B:Bands 1 and 5 appear similar when band 1 is horizontally flipped.Band 1 appears to be flanked by vertical discontinuities when background levels are adjusted.Lanes 1, 5, and 7 appear to have similar patterns within the background.In the p-mTOR panel:In the Keap1 panel, lanes 2 and 5 appear to have similar patterns within the background.In the Actin panel, lanes 5 and 8 appear to have similar patterns within the background.In the S6K panel, lanes 2 and 8 appear to have similar patterns within the background.In Figure 4B:In the p-mTOR panel, lanes 5 and 6 appear to have similar background patterns when lane 5 is horizontally flipped.In Figure 5A:Lanes 4 and 8 appear to have similar features within the background.There appears to be a vertical discontinuity between lanes 7 and 8.In the Actin panel:In Figure 5B:In the Actin panel, when levels are adjusted to visualize background, lanes 1 and 3 appear to have similar features within the background.In Figure 5C:Lanes 5 and 7 appear to have similarities in both the bands and background features.Bands 6 and 8 appear to be similar.In the Actin panel:The corresponding author stated that the underlying data for this article , 2 is noPLOS ONE Editors retract this article. YC & LZ did not agree with the retraction and stand by the article\u2019s findings. ECB responded but neither agreed nor disagreed with the retraction. YX, ZL, and AM either did not respond directly or could not be reached.In light of the above concerns with Figures 3B, 4B, and 5A-C which question the validity of these data, and in the absence of the underlying data required to resolve these concerns, the"}
{"text": "Microsystems & NanoengineeringCorrection to: 10.1038/s41378-023-00532-0 published online 16 May 20231, it was noticed that the phrase \u2018DNA sequencing\u2019 is incorrect, which should be replaced by \u2018biosensing\u2019.Correction Following publication of the original articleThe original paper has been updated."}
{"text": "There was an error in the original publication . The autA correction has been made to \u201cSection 3.2\u201d:p < 0.05) (see Table 3). For daughters, there were no significant comment variables (see Table 2).There were no significant comment variables when exploring parental comments to all adolescents (see Table 1); however, when exploring gendered dyads, mothers\u2019 positive comments to sons on eating were significantly related to higher BMI at one-year follow-up (RE: 2.49; 95% CI: 0.57\u20134.41 The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. The original publication has also been updated."}
{"text": "Retraction Note: BMC Public Health 9, 241 (2009)10.1186/1471-2458-9-241The Editor has retracted this article due to the author\u2019s inability to provide documentation of approval from an ethics committee.Ramesh Adhikari does not agree with this retraction. Jyotsna Tamang has not responded to correspondence from the Editor about this retraction."}
{"text": "After having been in contact with the authors, they agreed with the decision to retract the paper. The Editor apologizes to the readership for any inconvenience caused.The authors requested that a corrigendum be published to rectify this problem; however, after having conducted an independent analysis of the data in the Editorial Office, we have noticed that the data shown in Figs. 5A and 6C are strikingly similar to data appearing in different form in other articles published in another journal, mainly written by different authors at different research institutions. Owing to the fact that the contentious data in the above article were already under consideration for publication, or had already been published, elsewhere at the time it was submitted to"}
{"text": "Retraction Note: BMC Public Health (2022) 22:194010.1186/s12889-022-14341-zThe Editors have retracted this article after readers raised concerns around the methodology. A post-publication review highlighted concerns about the assumption of \u20180\u2019 prevalence of e-cigarette use in 2010 which contradicts available data; this assumption is not fully supported by the sensitivity analyses performed by the authors. Therefore, the Editors have lost confidence in the results reported by the article. None of the authors agree to this retraction."}
{"text": "There are errors in the Funding section. The correct Funding statement is: Specific grant number: GST03 Initials of authors who received award: AvS Specific grant number: EDU/0500057415 Initials of authors who received award: AvS, HYFull names of commercial companies that funded the study or authors: no commercial company funded the study or authors.Work preparatory to this meta-analysis was funded by the Organization for Economic Cooperation and Development (Contract Reference: EDU/0500057415).The systematic literature search and the coding for this meta-analysis was funded by the Global TIES for Children Research Center at New York University Abu Dhabi (GST03).https://nyuad.nyu.edu/en/research/faculty-labs-and-projects/global-ties-for-children.htmlURL to sponsor\u2019 website: The funders (other than the named authors) had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript."}
{"text": "Missing CitationIn the original publication , refs 22,3 were With these corrections, the order of some references have been adjusted accordingly. The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "Retraction note: Cell Biosci (2019) 9:2810.1186/s13578-019-0290-2The Editor-in-Chief has retracted this article because of concerns that a number of panels in Figs.\u00a02d, 4d and 4e are duplicated from previously published articles. Specifically:The eight panels in Fig.\u00a02d appear to be the same as panels in Fig.\u00a02B of .Eleven of the panels in Fig.\u00a04d appear to be the same as panels in Fig.\u00a02C of .Five of the panels in Fig.\u00a04e appear to overlap with panels in Fig.\u00a03A of .The Editor-in-Chief therefore no longer has confidence in the validity of the data reported. None of the authors has responded to correspondence from the Publisher about this retraction."}
{"text": "NAR Genomics and Bioinformatics, Volume 3, Issue 2, June 2021, lqad031, https://doi.org/10.1093/nargab/lqad031https://hugheslab.ccbr.utoronto.ca/supplementary-data/HumanGeneEnds/) , is erroneous. This file gave the locations and scores of all the cryptic Cleavage and Polyadenylation (CPA) sites discovered by the \u2018baseline\u2019 Random Forests classifier, and it was used in later parts of the paper, mainly Figure 6.In December 2022, the Authors alerted the Editors that the Cryptic_dataset.bed file originally posted on the project web site  .Shuffled motifs performed no better than real motifs  , presumably because the PAS is mostly a homopolymer (consensus AAUAAA) , so shuffling it (and related motifs) produces a related homopolymer.The corrected Figure 6 therefore reaches a very different biological conclusion from the original paper. The original paper speculated that many factors make small contributions to CPA site definition, but this new result instead suggests only that the current models of the PAS sequence will benefit from tweaking.https://doi.org/10.1093/nargab/lqad031. The .bed file has been replaced with the rebuilt version on the project web site.Given the circumstances, the Authors are retracting the original version of the article and replacing it with a new version, which has been reviewed and accepted by the editors. The new version has been republished as"}
{"text": "Authors H\u00e9l\u00e8ne Tourri\u00e8re, Karim Chebli, Latifa Zekri, Edouard Bertrand, and Jamal Tazi agree with the retraction of"}
{"text": "The Royal Society of Chemistry is publishing this expression of concern in order to alert readers that concerns have been raised regarding the reliability of the XRD data in Fig. 3a and the PL spectroscopy data in Fig. S2. An investigation is underway, and an expression of concern will continue to be associated with the article until a final outcome is reached.Laura Fisher2nd November 2023RSC AdvancesExecutive Editor,"}
{"text": "Error in Figure, as published. The corrected  appears below. The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated.In the original publication , there w"}
{"text": "Correction to: Psychopharmacologyhttps://doi.org/10.1007/s00213-022-06191-9After publication of this paper, the authors inadvertently excluded Dr. Pagano Zottola from the list of authors and that the journal Psychopharmacology has no responsibility for the omission.All authors agree to correct the list of authors as follows:Antonio C. Pagano Zottola4,5,7, Valeria Orr\u00f93, Valentina Serra3, Edoardo Fiorillo3, Paola Fadda1,6, Giovanni Marsicano4,5,Maria Antonietta De Luca1Giulia Margiani#,1, Maria Paola Castelli #,1, Nicholas Pintori1, Roberto Frau1,2, Maria Grazia Ennas1, 4 INSERM, U1215 NeuroCentre Magendie, Bordeaux, France5 University of Bordeaux, Bordeaux, France7 Institut de Biochimie et G\u00e9n\u00e9tique Cellulaires, UMR 5095, Bordeaux FranceThe original article has been corrected."}
{"text": "The authors would like to state that they inadvertently omitted one of the authors when preparing the manuscript. The authors of this work are as follows:1, Nata\u0161a Ko\u010dar Mlinari\u010d2, Peter Raspor3 and Iztok Jo\u017ee Ko\u0161ir1*Miha Ocvirk1Slovenian Institute of Hop Research and Brewing, C. \u017dalskega tabora 2, 3310 \u017dalec, Slovenia2Pivovarna La\u0161ko Union d.o.o., Pivovarni\u0161ka ulica 2, 1000 Ljubljana, Slovenia3Biotechnical Faculty, University of Ljubljana, Jamnikarjeva 101, 1000 Ljubljana, Slovenia"}
{"text": "Following publication, concerns were raised regarding the integrity of the images in the published figures. The authors failed to provide the raw data or a satisfactory explanation during the investigation, which was conducted in accordance with Frontiers\u2019 policies. Given the concerns about the validity of the data, and the lack of raw data, the editors no longer have confidence in the findings presented in the article.The authors agree to this retraction.This retraction was approved by the Chief Editors of Frontiers in Pharmacology and the Chief Executive Editor of Frontiers."}
{"text": "Following the publication of this article , an erroSpecifically, the authors had sought to delete Scarb1 in cells of the osteoblast lineage but used the C57BL/6N-Scrib<tm1c(NCOM)Mfgc>/Tcp conditional allele which encodes the protein Scrib, not the protein Scarb1.Bone [The authors would also like to alert the readership that the same error occurred in another of their recent articles, which has also been retracted . A readeBone  identifiThe authors regret this error that nullifies the conclusions of the paper. In light of this issue, the authors retract the article.All authors agree with the retraction and apologize for the issues with the published article."}
{"text": "Bioscience Reports, at the request of the Editor-in-Chief and the Editorial Board, following receipt of a notification from a reader alerting the Editorial Board to an image that seems to also appear in other papers by unrelated authors.This Retraction follows an Expression of Concern relating to this article previously published by Portland Press. This article is being retracted from Specifically, the Figure 3C Inhibitor NC panel seems to appear as the Figure 2D Si-Tcf3#3 image from He et al. 2019 (doi: 10.1042/bsr20180369) and as the 143B/sh-VAV3+inhibitor panel of Figure 6E from Xiao et al. 2020 (doi: 10.18632/aging.103762).The authors have been contacted with regards to the retraction and have not responded to the Journal's queries or the concerns raised. Given the extent of the issues raised, the Editorial Board stand by the decision to retract the article."}
{"text": "They also wish to apologize to the readership of the Journal for any inconvenience caused.The revised version of"}
{"text": "After this article  was publSpecifically:In Fig 1A, the Thr217 control bands appear similar to the Ser238 control bands.In Fig 1C, the Ser235 AD bands appear similar to the Ser413 AD bands.In Fig 2A, there appear to be vertical discontinuities between all bands in the \u03b1-Syn panel and between the Control and PD-FC bands in the \u03b3-Syn panel.In Fig 2B, the second \u201ccontrol\u201d band in the \u03b2-Syn panel appears to be flanked by vertical discontinuities.PLOS ONE Editors remain concerned about the issues contained within these figures.The authors did not respond to the concerns that were raised regarding these figures, and no underlying data was provided for editorial review. Accordingly these concerns cannot be resolved and the PLOS ONE Editors issue this Expression of Concern.In light of the above concerns, the All authors either did not respond directly or could not be reached."}
{"text": "After this article  was publIn addition, concerns were raised about some aspects of the methodology in . SpecifiIn response to queries about the methodology, the corresponding author stated that the results and hypothesis development/theoretical framework in  are corrPLOS ONE article. This institution\u2019s investigation did not include interviews or research record reviews for the authors of [The complainants\u2019 institution investigated the concern that aspects of  overlap thors of , who areThe corresponding author refuted the claims and stated that the work reported in  was not PLOS ONE editors issue this Expression of Concern.PLOS considers that the methodology concerns are resolved. However, we were unable to obtain input from Chongqing University as needed to clarify the concerns about ownership, permissions, and similarities to pre-existing unpublished work. Therefore, the"}
{"text": "Background: Histamine H2 receptor antagonists are a group of drugs that inhibit gastric juice secretion in gastrointestinal diseases. However, there is evidence to suggest that H2 blockers have a broader spectrum of activity. The antioxidant properties of H2 blockers have not been fully elucidated, and their anti-glycation potential has not been studied to date. Therefore, this is the first study to compare the antioxidant and antiglycation potentials of the most popular H2 antagonists  on protein glycoxidation in vitro. Methods: Bovine serum albumin (BSA) was glycated using sugars  as well as aldehydes . Results: In the analyzed group of drugs, ranitidine was the only H2 blocker that significantly inhibited BSA glycation in all tested models. The contents of protein carbonyls, protein glycoxidation products , and early (\u2193Amadori products) and late-stage (\u2193AGEs) protein glycation products decreased in samples of glycated BSA with the addition of ranitidine relative to BSA with the addition of the glycating agents. The anti-glycation potential of ranitidine was comparable to those of aminoguanidine and Trolox. In the molecular docking analysis, ranitidine was characterized by the lowest binding energy for BSA sites and could compete with protein amino groups for the addition of carbonyl groups. H2 blockers also scavenge free radicals. The strongest antioxidant properties are found in ranitidine, which additionally has the ability to bind transition metal ions. The systematic literature review also revealed that the anti-glycation effects of ranitidine could be attributed to its antioxidant properties. Conclusions: Ranitidine showed anti-glycation and antioxidant properties. Further research is needed, particularly in patients with diseases that promote protein glycation. Oxidative stress is defined as an imbalance between the generation of reactive oxygen species (ROS) and antioxidants in the body . This pr\u2022O2\u2212 production in granulocytes, whereas ranitidine and famotidine did not elicit such a response sulfanyl}ethyl)guanidine), ranitidine ((E)-N-{2-[({5-[(Dimethylamino)methyl]-2-furyl}methyl)sulfanyl]ethyl}-N\u2019-methyl-2-nitro-1,1-ethenediamine), and famotidine (3-[[[[2-((Diaminomethylene)amino]thiazol-4-yl]methyl]thio]-N\u2019-sulfamoylpropanimidamide), are used in the treatment of gastrointestinal inflammations  12]. H2. H212]. response . In viewThe literature review was conducted according to PRISMA 2020 criteria. A description of the inclusion and exclusion criteria is provided in the Materials and Methods. Three independent researchers performed an initial data analysis based on manuscript titles and abstracts. In the next stage, the selected articles were read and assessed for eligibility based on the adopted inclusion/exclusion criteria. Cohen\u2019s kappa coefficient (\u03ba) (\u03ba = 0.91) was used to measure inter-rated reliability. To ensure high data quality, all manuscripts were assessed for methodology, and the following data were gathered: author names and affiliations, year of publication, research project, sample size, inclusion and exclusion criteria, study duration, and results. The systematic review yielded 868 research articles in the Medline database (PubMed). Of those, 782 were rejected due to misleading titles. Eighty-six abstracts were read, and twenty-two of those were assessed for eligibility based on the adopted inclusion/exclusion criteria. Fourteen articles were unrelated to the studied topic. Ultimately, only eight research articles were included in the study. A flowchart of the systematic review process is presented in \u2022O2\u2212) and hydrogen peroxide (H2O2) in human neutrophils [\u2022O2\u2212) [\u2022OH) in various in vitro models [\u2022NO) radicals. Famotidine is a more potent scavenger of \u2022NO radicals than ranitidine and cimetidine [The results of the literature review indicate that cimetidine and famotidine inhibit the production of superoxide (trophils . Ranitids [\u2022O2\u2212) , as wells [\u2022O2\u2212) . Ranitido models ,24. The o models . H2 antametidine . Ranitidmetidine , as wellmetidine . The detailed results of the literature review are presented in the Various glycation agents, including sugars (glucose (Glc), fructose (Fru), galactose (Ga), and ribose (Rib)) and aldehydes  and methylglyoxal (MGO)) were used in this study due to differences in the glycation kinetics of BSA. Human albumin is glycated mainly by D-glucose . In the The content of protein glycoxidation products (dityrosine and N-formylkynurenine) was considerably higher in samples of BSA with the addition of glucose than in BSA alone. The dityrosine contents were significantly lower in BSA+Glc+aminoguanidine (\u219350.1%), BSA+Glc+Trolox (\u219345.1%), BSA+Glc+ranitidine (\u219387.9%), and BSA+Glc+famotidine (\u219311.2%) than in BSA+Glc. The dityrosine content was lower in BSA+Glc+ranitidine (\u219378.9%) than in BSA. In turn, the dityrosine contents were higher in BSA+Glc+cimetidine (\u219169.9%) and BSA+Glc+famotidine (\u219150.8%) than in BSA. The contents of N-formylkynurenine were lower in BSA+Glc+aminoguanidine (\u219318.6%), BSA+Glc+Trolox (\u219321.5%), BSA+Glc+ranitidine (\u219375.4%), and BSA+Glc+famotidine (\u219311.3%) than in BSA+Glc. The content of N-formylkynurenine was also considerably lower in BSA+Glc+ranitidine (\u219375.6%) and higher in BSA+Glc+aminoguanidine (\u219193.6%), BSA+Glc+cimetidine (\u2191127.4%), BSA+Glc+Trolox (\u219187.6%), and BSA+Glc+famotidine (\u2191110.3%) than in BSA A,B.The content of protein glycation products (Amadori products and AGEs) was higher after the addition of glucose (BSA+Glc) than in BSA alone. The contents of Amadori products were lower in BSA+Glc+aminoguanidine (\u219332.3%), BSA+Glc+Trolox (\u219320.4%), BSA+Glc+ranitidine (\u219345.9%), and BSA+Glc+famotidine (\u21937.2%) than in BSA+Glc. The contents of Amadori products were higher in BSA+Glc+aminoguanidine (\u2191275.9%), BSA+Glc+Trolox (\u2191335.2%), BSA+Glc+ranitidine (\u2191203.6%), BSA+Glc+cimetidine (\u2191425.9%), and BSA+Glc+famotidine (\u2191407.6%) than in BSA. The contents of AGEs were lower in BSA+Glc+aminoguanidine (\u219329.3%), BSA+Glc+Trolox (\u219327.4%), BSA+Glc+ranitidine (\u219391.5%), and BSA+Glc+famotidine (\u219314.3%) than in BSA+Glc. The contents of AGEs were considerably higher in BSA+Glc+aminoguanidine (\u219140.3%), BSA+Glc+Trolox (\u219144.9%), BSA+Glc+cimetidine (\u219193.6%), and BSA+Glc+famotidine (\u219168.2%), and lower in BSA+Glc+ranitidine (\u219380.8%) than in BSA C,D. The content of PCs was higher after the addition of glucose (BSA+Glc) than in BSA alone. The content of PCs was higher in BSA+Glc+famotidine (\u219162.3%) than in BSA+Glc. The contents of PCs were higher in BSA+Glc+cimetidine (\u2191262.3%) and BSA+Glc+famotidine (\u2191344.2%) than in BSA. The content of TTs was lower in BSA+Glc+ranitidine (\u219351.8%) than in BSA+Glc. In comparison with BSA, the contents of TTs were lower in BSA+Glc and in BSA+Glc after the addition of aminoguanidine, Trolox, ranitidine, cimetidine, and famotidine  E,F.The contents of protein glycoxidation products (dityrosine and N-formylkynurenine) were considerably higher in BSA with the addition of fructose than in BSA alone. The dityrosine contents were significantly lower in BSA+Fru+aminoguanidine (\u219353%), BSA+Fru+Trolox (\u219347%), BSA+Fru+ranitidine (\u219385%), BSA+Fru+cimetidine (\u219350%), and BSA+Fru+famotidine (\u219353%) than in BSA+Fru. The dityrosine contents were also significantly lower in BSA+Fru+aminoguanidine (\u219321%), BSA+Fru+ranitidine (\u219375%), BSA+Fru+cimetidine (\u219317%), and BSA+Fru+famotidine (\u219321%) than in BSA. The contents of N-formylkynurenine were lower in BSA+Fru+aminoguanidine (\u219393%), BSA+Fru+Trolox (\u219379%), BSA+Fru+ranitidine (\u219386%), BSA+Fru+cimetidine (\u219350%), and BSA+Fru+famotidine (\u219348%) than in BSA+Fru. The contents of N-formylkynurenine were also considerably lower in BSA+Fru+aminoguanidine (\u219384%), BSA+Fru+Trolox (\u219350%), and BSA+Fru+ranitidine (\u219367%), but higher in BSA+Fru+famotidine (\u219121%) than in BSA G,H.The contents of protein glycation products (Amadori products and AGEs) were also higher after fructose addition (BSA+Fru) than in BSA alone. In turn, the contents of Amadori products were significantly lower in samples of BSA+Fru+aminoguanidine (\u219361%), BSA+Fru+Trolox (\u219347%), BSA+Fru+ranitidine (\u219369%), BSA+Fru+cimetidine (\u219349%), and BSA+Fru+famotidine (\u219351%) than in BSA+Fru. The contents of Amadori products were higher in BSA+Fru+aminoguanidine (\u2191116%), BSA+Fru+Trolox (\u2191194%), BSA+Fru+ranitidine (\u219172%), BSA+Fru+cimetidine (\u2191183%), and BSA+Fru+famotidine (\u2191172%) than in BSA. The contents of AGEs were considerably higher in BSA+Fru+ranitidine (\u219196%), BSA+Fru+cimetidine (\u2191164%), and BSA+Fru+famotidine (\u2191138%) than in BSA I,J. The content of PCs was higher in the presence of fructose (BSA+Fru) than in BSA alone (\u2191177%), and lower in BSA+Fru+ranitidine (\u219372%) than in BSA+Fru. The contents of TTs were lower in BSA with the addition of fructose (BSA+Fru), aminoguanidine, Trolox, ranitidine, cimetidine, and famotidine  than in BSA alone. In comparison with BSA+Fru, the TT contents increased after the addition of aminoguanidine, Trolox, ranitidine, cimetidine, and famotidine  K,L.The contents of protein glycoxidation products (dityrosine and N-formylkynurenine) were considerably higher in BSA samples with the addition of galactose than in BSA alone. The dityrosine contents were lower in BSA+Gal+aminoguanidine (\u219324.2%), BSA+Gal+Trolox (\u219329.9%), BSA+Gal+ranitidine (\u219392.6%), and BSA+Gal+famotidine (\u219311.5%) than in BSA+Gal. The dityrosine contents were lower in BSA+Gal+ranitidine (\u219387.5%) and higher in BSA+Gal+aminoguanidine (\u219127.2%), BSA+Gal+Trolox (\u219117.6%), BSA+Gal+cimetidine (\u219168.7%), and BSA+Gal+famotidine (\u219148.7%) than in BSA. The contents of N-formylkynurenine were lower in BSA+Gal+aminoguanidine (\u219321.9%), BSA+Gal+Trolox (\u219334.8%), and BSA+Gal+ranitidine (\u219386.2%) than in BSA+Gal. The contents of N-formylkynurenine were lower in BSA+Gal+ranitidine (\u219367.5%) and higher in BSA+Gal+aminoguanidine (\u219183.6%), BSA+Gal+Trolox (\u219153.4%), BSA+Gal+cimetidine (\u2191150.6%), and BSA+Gal+famotidine (\u2191122.6%) than in BSA M,N.The contents of protein glycation products  were higher after the addition of galactose  than in BSA alone. The contents of Amadori products were lower in BSA+Gal+aminoguanidine (\u219323.9%), BSA+Gal+Trolox (\u219314.9%), and BSA+Gal+ranitidine (\u219335.5%) than in BSA+Gal. The contents of Amadori products were higher in BSA+Gal+aminoguanidine (\u2191314.6%), BSA+Gal+Trolox (\u2191363%), BSA+Gal+ranitidine (\u2191251%), BSA+Gal+cimetidine (\u2191451.7%), and BSA+Gal+famotidine (\u2191453.9%) than in BSA. The contents of AGEs were lower in BSA+Gal+aminoguanidine (\u219324.8%), BSA+Gal+Trolox (\u219327.9%), BSA+Gal+ranitidine (\u219392.3%), and BSA+Gal+famotidine (\u219312.1%) than in BSA+Gal. The contents of AGEs were lower in BSA+Gal+ranitidine (\u219384.8%) and higher in BSA+Gal+aminoguanidine (\u219147.5%), BSA+Gal+Trolox (\u219141.5%), BSA+Gal+cimetidine (\u2191103.3%), and BSA+Gal+famotidine (\u219172.4%) than in BSA O,PThe content of PCs was higher after the addition of galactose  than in BSA alone. The contents of PCs were lower in BSA+Gal+Trolox (\u219356.9%), BSA+Gal+ranitidine (\u219334.1%), and BSA+Gal+cimetidine (\u219334.5%) than in BSA+Gal. The contents of PCs were higher in BSA+Gal+aminoguanidine (\u2191114.4%) and BSA+Gal+famotidine (\u2191111.3%) than in BSA. The contents of TTs were higher in BSA+Gal+aminoguanidine (\u2191140.9%) and BSA+Gal+Trolox (\u2191112.1%) than in BSA+Gal. In comparison with BSA, the contents of TTs were lower in BSA+Gal and in BSA+Gal with the addition of aminoguanidine, Trolox, ranitidine, cimetidine, and famotidine  Q,R.The contents of protein glycoxidation products (dityrosine and N-formylkynurenine) were considerably higher in BSA samples with the addition of ribose than in BSA alone. The dityrosine contents were lower in BSA+Rib+aminoguanidine (\u219353.3%), BSA+Rib+Trolox (\u219347.8%), BSA+Rib+ranitidine (\u219369.8%), and BSA+Rib+famotidine (\u219313.2%) than in BSA+Rib. The dityrosine contents were lower in BSA+Rib+aminoguanidine (\u219320.9%) and BSA+Rib+ranitidine (\u219347.8%) than in BSA. In turn, the dityrosine contents were higher in BSA+Rib+cimetidine (\u219161.9%) and BSA+Rib+famotidine (\u219146.3%) than in BSA. The contents of N-formylkynurenine were lower in BSA+Rib+aminoguanidine (\u219383.7%), BSA+Rib+Trolox (\u219379.2%), BSA+Rib+ranitidine (\u219364.4%), and BSA+Rib+famotidine (\u219314.8%) than in BSA+Rib. The contents of N-formylkynurenine were considerably lower in BSA+Rib+aminoguanidine (\u219383.4%), BSA+Rib+Trolox (\u219350.2%), and BSA+Rib+ranitidine (\u219315%), and higher in BSA+Rib+cimetidine (\u2191125.4%) and BSA+Rib+famotidine (\u2191103.5%) than in BSA S,T.The content of protein glycation products (Amadori products and AGEs) was higher after the addition of ribose (BSA+Rib) than in BSA alone. The contents of Amadori products were lower in BSA+Rib+aminoguanidine (\u219360.7%), BSA+Rib+Trolox (\u219346.1%), and BSA+Rib+ranitidine (\u219338%) than in BSA+Rib. The contents of Amadori products were higher in BSA+Rib+aminoguanidine (\u2191114%), BSA+Rib+Trolox (\u2191193.4%), BSA+Rib+ranitidine (\u2191237.2%), BSA+Rib+cimetidine (\u2191424.6%), and BSA+Rib+famotidine (\u2191431.8%) than in BSA. The contents of AGEs were lower in BSA+Rib+aminoguanidine (\u219342%), BSA+Rib+Trolox (\u219323.2%), BSA+Rib+ranitidine (\u219367.5%), and BSA+Rib+famotidine (\u219313.7%) than in BSA+Rib. The contents of AGEs were considerably higher in BSA+Rib+aminoguanidine (\u219115%), BSA+Rib+Trolox (\u219156.7%), BSA+Rib+cimetidine (\u219190.5%), and BSA+Rib+famotidine (\u219169.4%), and lower in BSA+Rib+ranitidine (\u219336.3%) than in BSA U,V. The contents of PCs were higher in BSA with the addition of ribose (BSA+Rib) than in BSA alone. The contents of PCs were lower in BSA+Rib+aminoguanidine (\u219347%) and BSA+Rib+Trolox (\u219337.6%) than in BSA+Rib. The contents of PCs were higher in BSA+Rib+ranitidine (\u2191147.8%), BSA+Rib+cimetidine (\u2191138.9%), and BSA+Rib+famotidine (\u2191164.2%) than in BSA. The contents of TTs were higher in BSA+Rib+aminoguanidine (\u2191185%) and BSA+Rib+Trolox (\u2191202.2%) than in BSA+Rib. The content of TTs was lower in BSA+Rib than in BSA. In comparison with BSA, the content of TTs decreased after the addition of aminoguanidine, Trolox, ranitidine, cimetidine, and famotidine to BSA+Rib  W,X. The content of protein glycoxidation products (dityrosine and N-formylkynurenine) was considerably higher in BSA samples with the addition of glyoxal than in BSA alone. The dityrosine contents were lower in BSA+GO+aminoguanidine (\u219377.3%), BSA+GO+Trolox (\u219344.9%), BSA+GO+ranitidine (\u219372.7%), BSA+GO+cimetidine (\u219345.1%), and BSA+GO+famotidine (\u219366%) than in BSA+GO. The dityrosine contents were higher in BSA+GO+cimetidine (\u219162.2%) and BSA+GO+Trolox (\u219162.6%) than in BSA. The contents of N-formylkynurenine were lower in BSA+GO+aminoguanidine (\u219364.4%), BSA+GO+Trolox (\u219356.6%), BSA+GO+ranitidine (\u219370.4%), BSA+GO+cimetidine (\u219343.7%), and BSA+GO+famotidine (\u219364.5%) than in BSA+GO. The contents of N-formylkynurenine were higher in BSA+GO+aminoguanidine (\u2191176.5%), BSA+GO+Trolox (\u2191236.9%), BSA+GO+ranitidine (\u2191130.2%), BSA+GO+cimetidine (\u2191337.6%), and BSA+GO+famotidine (\u2191176.1%) than in BSA A,B.The content of protein glycation products  was higher after the addition of glyoxal (BSA+GO) than in BSA alone. The contents of Amadori products were lower in BSA+GO+aminoguanidine (\u219337.3%), BSA+GO+Trolox (\u219331.9%), BSA+GO+ranitidine (\u219348%), BSA+GO+cimetidine (\u219339.9%), and BSA+GO+famotidine (\u219360.5%) than in BSA+GO. The contents of AGEs were lower in BSA+GO+aminoguanidine (\u219364.9%), BSA+GO+Trolox (\u219332.2%), BSA+GO+ranitidine (\u219372%), BSA+GO+cimetidine (\u219345.2%), and BSA+GO+famotidine (\u219367%) than in BSA+GO. The contents of AGEs were considerably higher in BSA+GO+Trolox (\u2191230.7%) and BSA+GO+cimetidine (\u2191167.1%) than in BSA C,D. The content of PCs increased after the addition of glyoxal (BSA+GO) in comparison with BSA alone. The contents of PCs were lower in BSA+GO+cimetidine (\u219333.1%) and BSA+GO+famotidine (\u219362.1%) than in BSA+GO. The content of TTs was higher in BSA+GO+cimetidine (\u219175.2%) than in BSA+GO. In comparison with BSA, the contents of TTs decreased in BSA+GO and in BSA+GO after the addition of aminoguanidine, Trolox, and famotidine  E,F.The content of protein glycoxidation products (dityrosine and N-formylkynurenine) was considerably higher in BSA samples with the addition of methylglyoxal than in BSA alone. The dityrosine contents were lower in BSA+MGO+aminoguanidine (\u219337.2%), BSA+MGO+Trolox (\u219331.9%), BSA+MGO+ranitidine (\u219374.7%), BSA+MGO+cimetidine (\u219337.7%), and BSA+MGO+famotidine (\u219353%) than in BSA+MGO. The dityrosine contents were higher in BSA+MGO+aminoguanidine (\u219187.7%), BSA+MGO+Trolox (\u2191103.6%), BSA+MGO+cimetidine (\u219186.1%), and BSA+MGO+famotidine (\u219140.5%) than in BSA. The contents of N-formylkynurenine were lower in BSA+MGO+aminoguanidine (\u219353.7%), BSA+MGO+Trolox (\u219340.3%), BSA+MGO+ranitidine (\u219376.6%), BSA+MGO+cimetidine (\u219336.8%), and BSA+MGO+famotidine (\u219354.9%) than in BSA+MGO. The contents of N-formylkynurenine were higher in BSA+MGO+aminoguanidine (\u2191260.1%), BSA+MGO+Trolox (\u2191363.8%), BSA+MGO+cimetidine (\u2191391.5%), and BSA+MGO+famotidine (\u2191250.4%) than in BSA G,H.The content of protein glycation products (Amadori products and AGEs) increased after the addition of methylglyoxal (BSA+MGO) relative to BSA alone. The contents of Amadori products were lower in BSA+MGO+aminoguanidine (\u219368.8%), BSA+MGO+Trolox (\u219348.4%), BSA+MGO+ranitidine (\u219347.4%) BSA+MGO+cimetidine (\u219345.1%), and BSA+MGO+famotidine (\u219350.9%) than in BSA+MGO. The contents of Amadori products were lower in BSA+MGO+aminoguanidine (\u219333.7%) and higher in BSA+MGO+cimetidine (\u219116.6%) than in BSA. The contents of AGEs were lower in BSA+MGO+aminoguanidine (\u219355%), BSA+MGO+Trolox (\u219355.9%), BSA+MGO+ranitidine (\u219375.6%), BSA+MGO+cimetidine (\u219338.3%), and BSA+MGO+famotidine (\u219355.4%) than in BSA+MGO. The contents of AGEs were higher in BSA+MGO+aminoguanidine (\u2191119.6%), BSA+MGO+Trolox (\u2191115%), BSA+MGO+cimetidine (\u2191201%), and BSA+MGO+famotidine (\u2191117.7%) than in BSA I,J.The content of PCs increased after the addition of methylglyoxal (BSA+MGO) relative to BSA alone. The contents of PCs were lower in BSA+MGO+aminoguanidine (\u219352%), BSA+MGO+Trolox (\u219332.1%), BSA+MGO+ranitidine (\u219336.2%) BSA+MGO+cimetidine (\u219346.8%), and BSA+MGO+famotidine (\u219354.9%) than in BSA+MGO. The contents of PCs decreased in BSA+MGO+aminoguanidine (\u219330.6%), BSA+MGO+ranitidine (\u21937.7%), BSA+MGO+cimetidine (\u219323%), and BSA+MGO+famotidine (\u219334.7%) relative to BSA. The contents of TTs were higher in BSA+MGO+ranitidine (\u2191177.4%), BSA+MGO+cimetidine (\u2191143.8%), and BSA+MGO+famotidine (\u2191143%) than in BSA+MGO. In comparison with BSA, the contents of TTs decreased in BSA+MGO and in BSA+MGO with the addition of aminoguanidine and Trolox . The contents of TTs were higher in BSA+MGO+ranitidine (\u219136.9%), BSA+MGO+cimetidine (\u219120.4%), and BSA+MGO+famotidine (\u219120%) than in BSA K,L.As the anti-glycation properties of H2 inhibitors may be due to their antioxidant properties, their ability to scavenge free radicals and bind transition metal ions was also assessed.\u2022O2\u2212), hydroxyl radicals (\u2022OH), nitric oxide (\u2022NO), hydrogen peroxide (H2O2), 2,2\u2019-azino-bis(3-ethylbenzothiazoline)-6-sulfonic acid (ABTS), and 2,2-diphenyl-1-picrylhydrazyl (DPPH) radicals. The strongest antioxidant properties were found in ranitidine, which additionally had an ability to bind transition metal ions. The iron chelating capacity of ranitidine was no different to that of Trolox, which is a potent model antioxidant (At the concentration tested (1 mM), H2 blockers had a scavenging capacity of 20\u201370% for superoxide anions  . RanitidH2 receptor antagonists are a group of drugs that inhibit gastric juice secretion in gastrointestinal diseases . HoweverBovine serum albumin and human albumin have a highly similar structure . Bovine In the group of the tested H2 blockers, only ranitidine considerably decreased the BSA glycoxidation rate. In most of the analyzed models, the contents of PCs (\u2193PCs), protein glycoxidation products (\u2193dityrosine and \u2193N-formylkynurenine), and early (\u2193Amadori products) and late-stage (\u2193AGEs) protein glycation products decreased in samples of glycated BSA with the addition of ranitidine relative to BSA with the addition of the glycating agents (positive control). Ranitidine also increased the TT concentration in Fru- and MGO-induced models of BSA glycation. Interestingly, in some cases, ranitidine decreased the rate of protein glycoxidation below the level noted in BSA samples without the addition of a glycating agent (negative control) . To ensure objectivity, the pharmacological potential of ranitidine was compared with that of reference substances with proven antioxidant (Trolox) and anti-glycation properties (aminoguanidine) ,40. At t\u2022O2\u2212, \u2022OH, \u2022NO, and H2O2, but also the synthetic radicals ABTS\u2022 and DPPH\u2022. Interestingly, the strongest antioxidant properties were found in ranitidine, which additionally had the ability to bind transition metal ions (\u2191FIC). The systematic literature review (\u2022OH which are produced when Fe2+ reacts with H2O2 (Fenton reaction) [\u2022O2\u2212 radicals [\u2022O2\u2212) in vivo [Three groups of substances have anti-glycation properties: (1) antioxidants, (2) compounds that break AGE-derived protein crosslinks (AGE-breakers), and (3) compounds that compete with protein amino groups for the addition of carbonyl groups. Therefore, the anti-glycation effects of H2 receptor antagonists, observed in this study, could be attributed to their antioxidant properties. This was confirmed by the results of our research. The tested H2 blockers had the ability to scavenge e review  also reveaction) ,46,47,48radicals ,49. Raniradicals . Ranitid in vivo . Ranitid\u2022OH radicals and chelating transition metal ions), and they inhibit the activation of the NF-\u03baB, mitogen-activated protein kinase (MAPK), and peroxisome proliferator-activated receptor-gamma (PPAR-\u0263) pathways in vivo [The anti-glycoxidative activity of ranitidine could be attributed to its molecular structure, although the present study did not provide evidence for the above. The presence of a dimethylaminomethyl group in five-member heterocyclic rings increases a drug\u2019s alkalinity . The het in vivo . TherefoH2 receptor antagonists have been used globally for more than four decades. Many gastrointestinal diseases intensify oxidative and carbonyl stress, and H2 blockers with potential antioxidant/anti-glycation activity can be helpful in optimizing pharmacotherapy. This is the first study to describe the anti-glycoxidant properties of ranitidine. Ranitidine is as effective as aminoguanidine and Trolox in inhibiting BSA glycation and oxidation, which is why further research is needed, particularly in patients with diseases that promote protein glycation . The anti-glycation properties of ranitidine may be due to its antioxidant activity and its ability to bind transition metal ions. The systematic literature review also revealed that H2 receptor blockers modulate redox homeostasis, carbonyl stress, and the inflammatory response in vivo, which also implies that further studies are recommended.Finally, the limitations of this study and the next steps should be discussed. In this experiment, we used sodium azide (as a preservative), which may have pro-oxidant properties. However, at the concentration used, the compound does not show this activity . The effThe literature review was conducted from the PubMed database, and it involved articles published between 1986 and 2023. The following keywords were used: ranitidine and antioxidant, ranitidine and oxidative stress, ranitidine and glycation, ranitidine and carbonyl stress, ranitidine and advanced glycation protein products, cimetidine and antioxidant, cimetidine and oxidative stress, ranitidine and ROS, cimetidine and ROS, famotidine and ROS, cimetidine and glycation, cimetidine and carbonyl stress, cimetidine and advanced glycation protein products, famotidine and antioxidant, famotidine and oxidative stress, famotidine and glycation, famotidine and carbonyl stress, and famotidine and advanced glycation protein products. The inclusion and exclusion criteria are presented in All reagents for the study were supplied by Sigma-Aldrich . Before the study, all solutions were passed through syringe member filters with a diameter of 0.22 mm .Absorption/fluorescence spectra were measured with the Infinite M200 PRO multimode plate reader .Bovine serum albumin was glycated using previously described methods ,62,63,64v:v) before the measurements. The results were standardized to the fluorescence of 0.1 mg/mL of quinine sulfate in 0.1 M sulfuric acid [Dityrosine (DT) and N-formylkynurenine (NFK) were identified by measuring fluorescence emission and excitation spectra at wavelengths of 325/434 nm and 330/415 nm. The samples were diluted with 0.1 M sulfuric acid  [The content of Amadori products was determined in a colorimetric analysis with the use of nitro blue tetrazolium (NBT). Absorbance was measured at a wavelength of 525 nm based on the molar extinction coefficient for monoformazan  .v:v) before readout. AGE-specific fluorescence was measured at a wavelength of 440/370 nm in a 96-well microplate reader.The content of AGEs was determined with the use of a spectrofluorometer. The samples were diluted with PBS  [The reaction between carbonyls and 2,4-dinitrophenylhydrazine  in oxidatively damaged proteins was used to determine the content of protein carbonyls (PCs). The absorbance of reaction products was measured in a colorimetric assay at 355 nm with the use of the absorption coefficient for 2,4-DNPH  .Total thiols (TTs) were quantified with the use of a spectrophotometer and Ellman\u2019s reagent in 0.1 M of phosphate buffer. The content of TTs was read from a standard curve for reduced glutathione (GSH) .The antioxidant properties of ranitidine, cimetidine, and famotidine solutions (1 mM) were also assessed by evaluating their effects on free radical scavenging and transition metal binding.2EDTA and 50 \u03bcL of pyrogallol . The mixture was then vigorously shaken by hand at 37 \u00b0C. The absorbance at a wavelength of 325 nm was measured against the Tris-HCl buffer every 30 s for a duration of 5 min. These measurements were taken at pH 7.4 [The experimental procedure involved mixing x \u03bcL of the sample solution with (2950 \u2212 x) \u03bcL of Tris-HCl buffer , which also contained 1 mM Nat pH 7.4 .The scavenging activity of hydroxyl radicals (\u2022OH) was determined using a modified method based on Su et al. . The reaThe nitric oxide (\u2022NO) scavenging activity of the ranitidine, cimetidine, and famotidine samples was measured using sodium nitroprusside as the NO donor following the method described by Nitha et al.  In brief2O2 was measured using the ferrous ion oxidation xylenol orange (FOX) reagent, which was prepared by combining butylated hydroxytoluene (BHT), sulfuric acid, xylenol orange, and ammonium ferrous sulfate in a 90% methanol\u2013water solution. The samples were mixed with 50 mM H2O2  and incubated for 30 min at room temperature. The H2O2 sample solution was then mixed with HPLC-grade methanol and FOX reagent, and the mixture was incubated for another 30 min. The absorbance of the ferric\u2013xylenol orange complex was measured at 560 nm [The scavenging activity of Ht 560 nm .The 2,2\u2019-azino-bis(3-ethylbenzothiazoline)-6-sulfonic acid (ABTS) assay was performed following a modified protocol of Wang et al. . In summThe free radicals scavenging activity was assessed using the Brand\u2013Williams  method. The ferric ion chelating (FIC) assay, as described by Hsu et al. , was utiMolecular docking is a computational technique for investigating the interaction between a ligand (often a drug molecule) and a macromolecule . The goal is to predict the ligand\u2019s optimal binding mode and affinity to the macromolecule, which can provide valuable information for the discovery and development of new drugs . The prep < 0.05. Statistical analyses were conducted in GraphPad Prism 9.0.0 .The results were expressed as the percentage of control samples (BSA with the addition of glycating factors). The statistical significance of the results was determined by one-way analysis of variance (ANOVA). Significant differences between means were identified using Tukey\u2019s post hoc test at"}
{"text": "In the past, before the smartphone boom, I was interested in using wearable methods to obtain quantitative parameters in PD.I am convinced that it could be useful and stimulating Together with other coauthors, we developed a specific pedometer for patients with Parkinson\u2019s disease, the parameters connected with the path being strategic and also for the diagnostic monitoring of this pathology .Subsequently, other authors and I developed a system for personal computers for monitoring the activity on the video terminal , which mmHealth today allows, as you have also highlighted [I believe that hlighted , new oppBased on what I wrote above, I would like to open a discussion on this topic with this comment with you or with other authors interested in the discussion.mHealth self-assessment technologies on PD.In particular, I would like to have an opinion on how you or other authors see the development of reply in this regard.I would, therefore, very much appreciate a"}
{"text": "Moreover, a pair of data panels showing the results from cell-cycle experiments purportedly performed under different experimental conditions in Fig. 4A appeared to be strikingly similar.Molecular Medicine Reports, the Editor has decided that this paper should be retracted from the Journal. The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Owing to the fact that the contentious data in the above article were already under consideration for publication prior to its submission to"}
{"text": "This is a peer-review report submitted for the paper \u201cThe Exchange of Informational Support in Online Health Communities at the Onset of the COVID-19 Pandemic: Content Analysis\u201d.My comments are as follows:1. The authors [2. Although you have mentioned that one coder is a limitation, it is an evitable limitation and needs to be overcome, or how can you ensure the accuracy of the results? I suggest that the authors recode the posts and responses by two coders (at least) who are familiar with this field.3. What are the criteria by which you determine the name of the coding and the definition of the coding?"}
{"text": "After having been in contact with the authors, they accepted the decision to retract the paper. The Editor apologizes to the readership for any inconvenience caused.Owing to the fact that the contentious data in the above article had already been published prior to its submission to"}
{"text": "After having been in contact with the authors, they did not agree with the decision to retract the paper. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editor's attention by a concerned reader that certain of the cell cycle plots shown in Fig. 5A, and western blotting data in Fig. 6A, on p. 1293 were strikingly similar to data appearing in different form in other articles by different authors at different research institutes. Owing to the fact that the contentious data in the above article had already been published, or were already under consideration for publication, elsewhere prior to its submission to"}
{"text": "The authors regret that the original version of our paper, unfortunately, contained two incorrect pictures in Figure 2A, where the images for the H&E and Masson staining pictures of the uIRI Sham were incorrect. The correct version of Figure 2A is shown below.The correction made in this erratum does not affect the original data and conclusions. The authors apologize for any inconvenience that the errors may have caused."}
{"text": "In the original publication , there w\u201c1. Introduction\u201d, \u201cParagraph 6\u201d: \u201cbrace night shift (NB)\u201d should be changed to \u201cscoliosis night brace (NB)\u201d.A correction has been made to \u201c2. Materials and Methods\u201d, \u201c2.2. Interventions\u201d, \u201c2.2.1. Hypercorrective Boston Brace Night Shift\u201d: The Title \u201cHypercorrective Boston Brace Night Shift\u201d should be changed to \u201cHypercorrective Boston Scoliosis Night Brace\u201d.A correction has been made to \u201c2. Materials and Methods\u201d, \u201c2.2. Interventions\u201d, \u201c2.2.1. Hypercorrective Boston Brace Night Shift\u201d: \u201chypercorrective Boston brace night shift\u201d should be changed to \u201chypercorrective Boston scoliosis night brace\u201d.A correction has been made to \u201cTable 6\u201d as published. Four data are missing in the NB group: Worse 7 (18), Unchanged 27 (71), Better 4 (10) and Indeterminable 0 (0). The corrected \u201c appears below.In the original publication, there was a mistake in \u201cReference 32\u201d as published. \u201cBoston Orthotics and Prosthetics. Boston Brace Night Shift Scoliosis Brace. Available online: https://www.bostonoandp.com/products/scoliosis-and-spine/boston-night-shift/ (accessed on 4 September 2020).\u201d Should be changed to \u201cCamp Scandinavia. Boston Skoliosis Night Brace. Available online: https://www.camp.se/produkter/ryggortoser/rigida/boston-skoliosis-night-brace-p28118 (accessed on 14 September 2021)\u201d.In the original publication, there was a mistake in The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "They also wish to apologize to the readership of the Journal for any inconvenience caused.After having asked the authors to provide an explanation of these data, they realized that this figure was inadvertently assembled incorrectly. They were, however, able to consult their original data, and the revised version of"}
{"text": "Molecules [The authors wish to add the following information to the Authors and Affiliation section of our paper published in olecules .Change in authorship (change in full name of Mr. Christodoulou from Paraschos Christodoulou to Paris Christodoulou).Addition of an extra affiliation to Mr. Paris Christodoulou as follows:Change fromAffiliation 1: Institute of Chemical Biology, National Hellenic Research Foundation, 11634 Athens, GreecetoAffiliation 1: Institute of Chemical Biology, National Hellenic Research Foundation, 11635 Athens, GreeceAffiliation 2: Department of Biochemistry and Biotechnology, University of Thessaly, 41500 Larissa, Greece"}
{"text": "In \u201cNormalizing Telemonitoring in Nurse-Led Care Models for Complex Chronic Patient Populations\u201d :e36346) the authors made two additions.In the original publication, one author was missed and the existing authors were incorrectly arranged. The authorship list was originally published as:Kayleigh Gordon, Emily Seto, Katie N Dainty, Carolyn Steele Gray, Jane DeLacyThis has been changed to read as follows:Kayleigh Gordon, Katie N Dainty, Carolyn Steele Gray, Jane DeLacy, Amika Shah, Emily SetoAdditionally, an Acknowledgments section has been added as follows:This research was made possible by the funding support from a Canadian Institutes of Health Research Personalized Health Catalyst Grant (Funding Reference Number 155443).The correction will appear in the online version of the paper on the JMIR Publications website on November 1, 2023 together with the publication of this correction notice. Because this was made after submission to PubMed, PubMed Central, and other full-text repositories, the corrected article has also been resubmitted to those repositories."}
{"text": "The purpose of this study is to investigate the genotype and allele distribution of MTHFR rs1801133 in the Chinese population, and to analyze the relationship between gene polymorphism of MTHFR rs1801133 and risk of childhood leukemia.Blood samples and clinical data of childhood leukemia cases (n=1132) and age-matched healthy controls (n=1053) were collected. Genotypes and allele distribution of MTHFR rs1801133 were detected by PCR-RFLP. Logistic regression model was generated to analyze the relation between MTHFR rs1801133 and susceptibility to childhood leukemia and the chemotherapy response.Age, sex, BMI and family history of tumor were comparable between childhood leukemia cases and healthy controls. Genotypes and allele distribution of MTHFR rs1801133 were remarkably correlated to the risk of childhood leukemia. Genotype risk of MTHFR rs1801133 was parallel to the susceptibility to childhood leukemia. Specifically, compared with people carrying AA allele of MTHFR rs1801133, higher risk of childhood leukemia may occur in people carrying AG+GG allele of MTHFR rs1801133 with a younger age (<15 years) or complete remission from chemotherapy.MTHFR rs1801133 gene polymorphism has a significant correlation with childhood leukemia. It is an important genetic susceptibility gene of childhood leukemia. The reliability of the results requires to be further validated by the high-quality research involving a large sample size in multi-center hospitals. Leukemia is a malignant disease attacking the hematopoietic system. It is the mostly diagnosed tumor in children. Based on disease course and cell differentiation, leukemia is classified to acute and chronic type. Acute leukemia (AL) covers about 95% of childhood leukemia The protein encoded by MHTFR (NADPH) is a key enzyme of folate metabolism. NAPDH catalyzes the conversion of 5, 10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine (hCY) remethylation to methionine Leukemia children (n=1132) and age-matched healthy controls (n=1053) were randomly recruited in Anhui Provincial Children\u2019s Hospital. Eligible leukemia children did not have other malignancies or received pre-chemotherapy. Childhood leukemia was independently diagnosed by two pathologists based on clinical symptoms, physical, imaging and histological examinations.Healthy controls were recruited from whom participated in physical examinations during the same period. They did not have blood connections to other participants. Family history of cancer was defined as the presence of cancer in any first-degree relatives . This study was approved by the institutional review committee of our hospital. All participants and their parents were informed consent.21H20BrN3, and analyzed.Genomic DNA was isolated and purified from peripheral blood lymphocytes by proteinase K digestion and phenol-chloroform method. MTHFR rs1801133 and its alleles were detected using PCR-RFLP . SNP primers were amplified at 95\u00b0C for 10 min, followed by 45 cycles at 95\u00b0C for 15 s and 60\u00b0C for 1 min. PCR products were cleaved by BccI, loaded on 1% DNA agarose gel containing C2 test. Risk factors of childhood leukemia were assessed by Logistic regression test, and results were expressed as OR and 95% CI. P<0.05 considered as statistically significant.Statistical Product and Service Solutions (SPSS) 22.0  was utilized for statistical analysis. Enumeration data were expressed as frequency (%). The HWE of control genotype distribution, and comparison of enumeration data were evaluated using the xP>0.05, A total of 1132 eligible leukemia children and 1053 age-matched healthy controls were recruited. By analyzing their clinical data, it is shown that age, sex, BMI and family history of tumor were comparable between childhood leukemia cases and healthy controls P>0.05, .P=0.005, OR=1.56 (1.15\u20132.13)) or AG+GG allele ) was identified in comparison to whom carrying AA allele. G allele of MTHFR rs1801133 ) predicted a higher risk of suffering from childhood leukemia than A allele.Genotypes and allele distribution of MTHFR rs1801133 were detected to be remarkably correlated to the risk of childhood leukemia . In partP=0.014) or complete remission .Logistic regression model was generated to analyze the relation between MTHFR rs1801133 and susceptibility to childhood leukemia and the pathology , Table 4ALL originates from lymphocyte progenitor cells. It is the most common hematological malignant disease in children. Malignantly proliferated immature hematopoietic stem cells are accumulated in peripheral blood and bone marrow, leading to suppression of hemopoietic function. In the meantime, malignant hematopoietic stem cells can infiltrate the liver, spleen, lymph nodes and other organs, resulting in hemorrhage, anemia, infection, and organ involvement manifestations MTHFR is a key enzyme affecting Hcy metabolism. MTHFR rs1801133 SNP is located in the MTHFR catalytic region Classified by genotypes of MTHFR rs1801133, we detected a higher susceptibility to childhood leukemia in people carrying GG or AG+GG allele in comparison to whom carrying AA allele. Moreover, people carrying G allele of MTHFR rs1801133 had a higher risk of suffering from childhood leukemia than whom carrying A allele. Potential influences of MTHFR rs1801133 polymorphism on clinical data of childhood leukemia cases and their chemotherapy response were further assessed. It is shown that higher risk of childhood leukemia may occur in people carrying AG+GG allele of MTHFR rs1801133 with a younger age (<15 years) or complete remission compared with people carrying AA allele of MTHFR rs1801133.Three limitations in the present study main limit the reliability of our conclusion. First of all, a relatively small sample size wound affect the results. Secondly, potential influences of the internal environment of the embryo, nutritional intake of the mother during pregnancy or other important factors are not taken into considerations. Thirdly, a possible effect of genotypes carried by parents on the risk of their offspring remains unclear. Collectively, our finding requires to be further validated by the high-quality research involving a large sample size in multi-center hospitals.MTHFR rs1801133 gene polymorphism has a significant correlation with childhood leukemia. It is an important genetic susceptibility gene of childhood leukemia.All the authors declare that they have no conflict of interest in this work."}
{"text": "Retraction Note: Cancer Cell Int (2019) 19:9710.1186/s12935-019-0812-3The Editors-in-Chief have retracted this article at the authors\u2019 request. After publication, concerns were raised regarding image similarities between this article and several other articles. Specifically:Figure\u00a02f 5-FU\u2009+\u2009ad-ctrl appears highly similar to Fig.\u00a03j Ctrl WT cells in ;Figure\u00a03e CIV-II blot appears highly similar to Fig.\u00a02a Cyclin D1 in [Figure\u00a03e CIII-core2 blot appears highly similar to Fig.\u00a04f mito-LC3 in [Figure\u00a04e Survivin appears highly similar to Fig.\u00a02e Cyclin D1 in [Figure\u00a07a t-JNK appears highly similar to Fig.\u00a01a GAPDH in .Additionally, Fig.\u00a04a has very unusual shapes for flow cytometry plots.The authors have stated that they misused the figures, which affected the accuracy of the data. The authors and the Editors-in-Chief therefore no longer have confidence in the presented data and the conclusions of this article.All authors agree to this retraction."}
{"text": "The authors regret that the acknowledgement of College Student Innovation and Entrepreneurship Training Program, Southwest University (S202210635259) is incorrect. The correct acknowledgement is College Student Innovation and Entrepreneurship Training Program, Southwest University (S202310635215).The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "These have been inserted into the version of the abstract currently available online, and the authors regret this error.In the original publication of this abstract, [Strezova A, Diez-Domingo J, Al Shawafi K et al. 114. Long-term Protection Against Herpes Zoster (HZ) by the Adjuvanted Recombinant Zoster Vaccine (RZV): Interim Efficacy, Immuno and Safety Results at Approximately 10 Years after Initial Vaccination, Open Forum Infectious Diseases, Volume 9, Issue Supplement_2, December 2022, ofac492.192"}
{"text": "There are errors in the Acknowledgments section. The correct Acknowledgments are as follows:We would like to acknowledge Maria Da Costa (UCSF), who consistently gave counsel during sample collection and DNA extraction, Vasco Chikwasha for his statistical expertise, which he contributed during the proposal writing stages and Eug\u00e9nie Lohmann for her contribution with R-studio commands. We also express our gratitude to Sister Mucheche, the nurse who recruited the women, the personnel at UZCHS-CTRC laboratory, the Norwegian HPV reference laboratory at Akershus University Hospital for their molecular expertise and technical support and the Parirenyatwa Hospital VIAC clinic staff for assisting during the recruitment phase. We are also very grateful to Prof. Jane R. Montealegre and all the other reviewers for their constructive critique and suggestions.Where authors are identified as personnel of the International Agency for Research on Cancer/World Health Organization, the authors alone are responsible for the views expressed in this article and they do not necessarily represent the decisions, policy, or views of the International Agency for Research on Cancer / World Health Organization.The authors would like to dedicate this paper to Babill Stray-Pedersen, in fond memory of her tireless dedication to female reproductive health. Babill passed away before the submission of the final version of this manuscript. Corresponding author RSDM accepts responsibility for the integrity and validity of the data collected and analyzed."}
{"text": "Furthermore, the authors also apologize to the readership for any inconvenience caused.The authors deeply regret this minor error, and can confirm that this error did not affect the conclusions reported in the paper. The authors are grateful to the Editor of"}
{"text": "Scientific Reportshttps://doi.org/10.1038/s41598-021-00994-0, published online 02 November 2021Retraction of: The Editors have retracted this article.After publication concerns were raised that the XRD spectra in Figure\u00a08 are identical and that the data points in Figure\u00a016 and Figure\u00a018 are the same although they report the results of different experiments. The authors are unable to provide the original data for examination. In addition, an investigation by the Editors has shown inappropriate changes in authorship during the review process. The Editors no longer have confidence in the results and conclusions presented.Jawad Ahmad disagrees with this retraction. Fahid Aslam, Jes\u00fas de-Prado-Gil and Shaker M.A.Qaidi did not respond to the correspondence from the Editors about this retraction. The Editors were not able to obtain current contact details for Rebeca Martinez-Garcia and Ameni Brahmia."}
{"text": "Journal of Clinical Medicine retracts the article entitled \u201cCardiovascular Disease and Exercise: From Molecular Mechanisms to Clinical Applications\u201d [The cations\u201d .Following publication, concerns were brought to the attention of the publisher regarding overlap with a previously published manuscript  with a dAdhering to our complaint\u2019s procedure, an investigation was conducted that confirmed the extensive use and dispersed nature of the overlap and the article is therefore retracted. Journal of Clinical Medicine. This retraction was approved by the Editor in Chief of the The authors agreed to this retraction."}
{"text": "Effect of intraoperative ventilation strategies on postoperative pulmonary complications: a meta-analysis By Lei M, Bao Q, Luo H, Huang P and Xie J. (2021) Front. Surg. 8:728056. doi: 10.3389/fsurg.2021.728056A Retraction of the Systematic Review Article The journal and Chief Editors retract the 4 October 2021 article cited above.Following publication, concerns were raised regarding abnormal similarities with the contents of other articles published by unrelated research groups. A subsequent investigation, which was conducted in accordance with Frontiers' policies, raised strong concerns over the authorship of the articles, resulting in a loss of confidence in the findings presented in the article.The authors have not responded to this retraction.This retraction was approved by the Chief Editors of Frontiers in Surgery and the Chief Executive Editor of Frontiers."}
{"text": "PNAS Nexus, Volume 2, Issue 6, June 2023, pgad179, https://doi.org/10.1093/pnasnexus/pgad179This is a correction to: Zoe A Purcell, Jean-Fran\u00e7ois Bonnefon, Humans feel too special for machines to score their morals, PNAS Nexus, it was discovered that this paper was missing a statement acknowledging compliance with the PNAS Nexus Human and Animal Participants and Clinical Trials policy:During a retroactive audit conducted by All studies in this paper were approved though the TSE-IAST Review Board for Ethical Standards in Research under the code 2021-03-001. In each study, all participants consented to participate.This error has been corrected in the original article."}
{"text": "DOI: https://doi.org/10.1039/C4RA04484C.Retraction of \u2018Investigation on corrosion protection and mechanical performance of minerals substituted hydroxyapatite coating on HELCDEB-treated titanium using pulsed electrodeposition method\u2019 by D. Gopi  RSC Advances article due to concerns with the reliability of the data in the published article.The Royal Society of Chemistry, with the agreement of the named authors, hereby wholly retracts this Repeating fragments can be observed in the cross-sectional SEM images of Fig. 4c, f and i, indicating that the images have been manipulated.1In addition, parts of the cross-sectional SEM image in Fig. 4c have been duplicated in another publication.The authors informed the editor that the characterization of the original samples was outsourced, and they do not have the original raw data for the published results.Given the significance of the concerns about the validity of the data, and the lack of raw data, the findings presented in this paper are not reliable.R. Pramod and Jishnu Dwivedi were contacted but did not respond.Signed: D. Gopi, A. Karthika, D. Rajeswari and L. Kavitha.Date: 16th March 2023.RSC Advances.Retraction endorsed by Laura Fisher, Executive Editor,"}
{"text": "Skin Res Technol. 2023;29:e13328. https://doi.org/10.1111/srt.13328Li S, Zhao X, Chen Y, Liu J. Therapeutic effects of mesoderm introduction of compound glycyrrhizin injection on the treatment of rosacea. In the \u201cFunding Information\u201d section, the text \u201cThe authors received no specific funding for this work.\u201d was incorrect. This should have read: \u201cThis study was supported by Xintai Key Research Project (2021ZC132).\u201dWe apologize for this error."}
{"text": "The authors wish to make a correction to this paper . In the The particle size of the synthesized ZnO NPs was examined by employing dynamic light scattering (DLS) technology using the Malvern zeta sizer . After removing the fabric from the synthesis solution, the remaining solution was centrifuged at 5000 rpm for 3 min to separate the solid ZnO NPs from the liquid, and then the separated solid ZnO NPs were dried in an air oven at 90 \u00b0C for 120 min. The obtained ZnO NPs were dispersed in deionized water with the help of an ultrasonic probe. Eventually, the DLS technique was employed.The authors wish to make the correction to Equation (9). The corrected equation is as follows:The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "The authors apologise that within the above article, Savelyev, A., & Jeong, C. , the imaThe correct image is as below.The authors would like thank Dr. B\u00e9la Kempf who drew their attention to this error."}
{"text": "This is a peer-review report submitted for the paper \u201cEmergence of the First Strains of SARS-CoV-2 Lineage B.1.1.7 in Romania: Genomic Analysis.\u201dFirst of all, the authors presented an important work about the new UK variant of COVID in Romania . I have In the Methods section, the authors mentioned that \u201cTwenty samples, collected from patients in the cities of Cluj, Craiova and Suceava counties from Romania were selected for analysis, including patients with possible contacts with UK infected individuals.\u201d In the Introduction section, the authors also described the first few possible UK variant cases in Romania.Are these 20 cases sequenced by authors related to those cases mentioned in the Introduction? If not, can authors provide some details about the subjects' past travel history? For example, did they stay in UK for more than 2 weeks before they traveled to Romania? And when were these samples collected? The timeline is important to understand how the disease spread and whether they are the first strains of B.1.1.7 in Romania.The authors claimed that \u201cthe Romanian strains bearing the particular ORF8 mutations described above clearly originated in the UK, which is also supported by the fact that the patient from Suceava county arrived in Romania from the UK.\u201d I have a similar question about the travel details of the patient as well as the timeline.From a public health standpoint, how did the authors deal with the \u201cnews\u201d of the new variant? Was there any communication with local officials or support for contact tracing?In the Discussion section, the authors described that \u201cMany European countries, including Romania, lag in genomic sequencing\u201d. Can the authors provide more details about why Romania lags in genomic sequencing for COVID? For example, cost, equipment, access to labs/institutes. This can help readers and other researchers to understand the issue."}
{"text": "Dear Editor,We have read with interest the article by Gu et al.\u00a0 \"Effectshttps://wwwn.cdc.gov/Nchs/Nhanes/Search/DataPage.aspx?Component=Laboratory&CycleBeginYear=2009). Accordingly, we would like to know how the authors got these data.The authors analyzed data of NHANES 2007\u20132010. However, we found that data on 25(OH)D from these two surveys cannot be downloaded from the website (We appreciate the authors for their work on this valuable and instructive topic and hope that there will be more research in this area."}
{"text": "The journal retracts the 18 April 2013 article cited above.Following publication, concerns were raised regarding the scientific validity of the article due to a duplication in Figure 2A. An investigation was conducted in accordance with Frontiers' policies, and the authors were given the chance to redo the experiments affecting the figure. Editorial assessment of the new data found the SEM values of the new experiments improbable, making the results of the study unreliable. Therefore, this article has been retracted.This retraction was approved by the Chief Editors of Frontiers in Cellular Neuroscience and the Chief Executive Editor of Frontiers. The authors do not agree to this retraction."}
{"text": "This article has been corrected at the request of the authors to correct the URLs for references 13 and 14 in the initial published version.They have been updated from https://c19hcq.org/ to https://c19early.org/z and https://c19ivm.org/, respectively. The authors deeply regret that these errors were not identified and addressed prior to publication."}
{"text": "Sci., 2023, 14, 10768\u201310776, https://doi.org/10.1039/D3SC03239F.Correction for \u2018Structurally divergent enantioselective synthesis of benzofuran fused azocine derivatives and spiro-cyclopentanone benzofurans enabled by sequential catalysis\u2019 by Rupkumar Khuntia  The authors regret that some relevant citations to previous work on annulation reactions with enynes were not included in the original reference list of the published article. Ref. 12 in the article should be corrected as shown in ref. The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Following the publication of this article , concernIn Fig 2C, lanes 2 and 6 in the left Beclin 1 panel appear similar.In Fig 2C, the left and right GAPDH panels appear similar despite representing different conditions.In Fig 4A Beclin 1 panel, when levels are adjusted to visualize the background, there appears to be vertical discontinuity between lanes 1 and 2.In the Beclin 1 panel in Fig 4C, when levels are adjusted, there are similar patterns in the background above the bands in lanes 1 and 5. In addition, in lane 5, the signal around the band appears to be discontinuous with the overall background of the panel.The L-02 cell line used as a control for healthy human hepatic tissue was found to be potentially contaminated by HeLa cells in a later study [The authors stated that the original, underlying data for the Western blots in this article are no longer available; however, they provided versions of the images that were cropped wider than the published panels.PLOS ONE Editors remain concerned about this figure.Regarding the concerns in Fig 2, the authors stated that the bands in lanes 2 and 6 were similar but were not identical. The authors stated that the similarities observed in the GAPDH panel were caused by an error during figure preparation and provided a replacement panel. In the absence of raw data, the The authors stated the vertical discontinuity in Fig 4A may be caused by a smear on the Western blot film. In the absence of original image data, these issues cannot be clarified.PLOS ONE Editors remain concerned about the issues involving this figure.Regarding the Beclin 1 panel in Fig 4C, several repeating patterns were observed in the background of the uncropped panel provided by the authors, in addition to the concerns raised in lanes 1 and 5 of the published panel. The authors stated that the discontinuous background was potentially caused by blemishes on the original film. The The authors stated that they were not aware of the potential contamination issues with the L-02 cell line at the time of this study, and they no longer have a sample of these cells to investigate. They commented that the morphology of L-02 and HeLa cells in this study was not similar as shown in Figs 1 and 3C of [PLOS ONE Editors retract this article.In light of the concerns affecting multiple figure panels that question the reliability of these data, the YFP did not agree with the retraction. YHS, ZBD, JZ, SJQ, BH, CYG. HY, WRL, and JF either did not respond directly or could not be reached."}
{"text": "Maternal vitamin D intake and BMI during pregnancy in relation to child\u2019s growth and weight status from birth to 8 years: a large national cohort study. BMJ Open 2021;11:e048980. doi: 10.1136/bmjopen-2021-048980Amberntsson A, Papadopoulou E, Winkvist A, The authors want to alert the readers on the updates done for tables 2-3 in the published version."}
{"text": "Moreover, unexpected similarities were identified comparing between a pair of the flow cytometric assay data panels in Fig. 4 on p. 3490, considering that these data were intended to show the results from differently performed experiments.Molecular Medicine Reports, the Editor has decided that this paper should be retracted from the Journal. The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Owing to the fact that the contentious data in the above article had already been published, or were already under consideration for publication, prior to its submission to"}
{"text": "Retraction: Salari et al. Diabetol Metab Syndr _#####################_10.1186/s13098-021-00733-5The Editor-in-Chief has retracted this article. After publication, concerns were raised regarding the reliability of the reported data, which the authors addressed by a Correction . HoweverAuthors Kamran Mansouri and Masoud Mohammadi disagree with this retraction. The other authors have not responded to correspondence regarding this retraction."}
{"text": "They also apologize to the readership for any inconvenience caused.The authors were able to re-examine their original data files, and realize how the errors were made during the assembly of this figure. The revised version of"}
{"text": "Following the publication and Correction of this article , 2, concIn Fig 3a, the SM-Only Day3 panel appears to partially overlap with the SM-Only Day14 panel.In Fig 4e, the SM-Only panel appears to partially overlap with the SM-GFP panel when rotated 180\u00b0.In Fig 7a, the SM-Only panel and the GFP panels appear more similar than would be expected from independent results.In Fig 8a, there appear to be repetitive elements within each panel, as well as repetitive elements between panels.PLOS ONE Editors retract this article.The corresponding author provided a response and underlying data for Figs 3, 4, 7, and 8, but these did not resolve the concerns raised with the article. In light of the concerns affecting multiple figure panels that question the integrity of these data, the SLR, CYZ, ZHS, LHC, XFH, HJD, and BL either did not respond directly or could not be reached. XLW and XJL responded but expressed neither agreement nor disagreement with the editorial decision."}
{"text": "The diagnosis of leukemia in a child is a difficult moment for the therapist and for the parents. Nevertheless, this moment is crucial and determining in the course of care and the therapeutic relationship.Determine the quality of diagnosis announcement among mothers of children with leukemia.A cross-sectional study was conducted at Aziza Othmana hospital department of haematology in Tunisia between June and July 2021.We have questioned the mothers about the announcement of the diagnosis: the space frame, the time provided and the availability of the doctor.We included 31 mothers, their middle age was 41 years old. Acute lymphoblastic leukemia is the most frequent type of cancer in our sample (94%).According to 4 mothers (13.3%), the diagnosis of leukemia was not announced before the start of treatment.The quality of the diagnostic announcement was judged to be good in 40% of cases (n=12), average in 12.7% (n=8) and mediocre in 20% of mothers (n=6).The space frame of the announcement was perceived as appropriate with respecting confidentiality in 18 mothers (69.2%).The time provided for the announcement was considered sufficient for 17 mothers (65.4%).The doctor who announced the diagnosis was described as available by 69.2% of the mothers and unavailable by 30.8% of the mothers.The quality of the diagnosis announcement amoung mothers of children with leukemia in our context is not optimal. Oncologists must be trained in diagnostic announcement and must be aware of the importance of this moment in the subsequent therapeutic relationship.None Declared"}
{"text": "The journal retracts the May 12, 2021, article cited above.Following publication, concerns were raised regarding the integrity of the images in the published figures. The authors failed to provide a satisfactory explanation during the investigation, which was conducted in accordance with Frontiers\u2019 policies. Given the concerns about the validity of the data, the editors no longer have confidence in the findings presented in the article.This retraction was approved by the Chief Editors of Frontiers in Oncology and the Chief Executive Editor of Frontiers.The authors agreed with this retraction."}
{"text": "This is a peer-review report submitted for the paper \u201cWaiting Time and Patient Satisfaction in a Subspecialty Eye Hospital Using a Mobile Data Collection Kit: Pre-Post Quality Improvement Intervention.\u201dIn this paper , the autIn the Abstract and Methods sections, what does \u201cODK\u201d stand for?I suggest moving the problem description to the study rational as the first paragraph of this section.In the methods section, the contents related to the data collection need to be expanded to include the type of data that were collected by data collectors.The methods of data collection should be explained clearly.In the Results section (page 11), the authors said, \u201cThe first 7 changes were implemented, which includes\u2026\u201d and \u201cFive of the originally proposed changes could not be implemented due to\u2026\u201d I think it is better if the authors either change the wording of the sentences or provide a complete explanation of the all changes. Then, the authors can explain which strategy was implemented and which one was not implemented.Unintended Outcomes subsection), the authors noted the following: \u201c\u2026the intervention appeared to have affected women adversely\u2026\u201d This section needs further explanations about the possible reasons for such an unintended outcome.In the Results section (I am wondering whether all changes were implemented at the same time or they were implemented one by one. In case of the second approach, the impact of each strategy on changing waiting times and improving patient satisfaction could be investigated separately and compared with other strategies.What were the possible reasons for non-significant increase in patient satisfaction while the waiting time was improved?Strengths and Limitations section, the sample size was relatively small. However, they need to explain more why they did not reach a larger sample size. What were the main limitations?As the authors noted in the Multimedia appendices were not available to me.Any survey instruments or questionnaires used for measuring patient satisfaction need to be added to the manuscript.I appreciate the authors for their time and efforts to implement our suggestions. However, some issues need further attention.The Introduction section started with the problem description. This section usually comes later and after describing the background. Hence, the coherence of the paragraphs should be revised. Moreover, the current subheadings in the Introduction section seem unnecessary and the authors can remove or reduce them.Strengths and Limitations section.As the authors said, they implemented all the changes together. However, each strategy or change might have a different impact on changing waiting times and improving patient satisfaction, which was worth investigating. If the authors did not do so, it is better to add this point to the"}
{"text": "There is an error in affiliation 1 for authors Yun Sun Lee, Jin-Kyung Kim, Jee Young Park, Nur Kholilatul Izzah, Hyun-Seung Park, and Tae-Jin Yang. The correct affiliation 1 is: Department of Agriculture, Forestry and Bioresources, Plant Genomics and Breeding Institute, College of Agriculture and Life Sciences, Seoul National University, Seoul, Republic of Korea."}
{"text": "Obviously, such actions must be based on sovereignty, the principle of human dignity, and fundamental rights provided for by law.Overall, the authors are totally in agreement that the scientific community has been working hard to come up with creative approaches to pesticide pollution reduction.The authors declare no conflicts of interest."}
{"text": "Correction to: European Journal of Nutrition (2022) 61:2517\u20132530 10.1007/s00394-022-02822-1The original version of this article unfortunately contained a mistake. The affiliation details for Authors\u2019 Marina Liso and Marcello Chieppa were incorrectly given asInstitute of Research, National Institute of Gastroenterology \u201cS. de Bellis\u201d, Castellana Grotte, Italybut should have beenNational Institute of Gastroenterology S. De Bellis, IRCCS Research Hospital, Via Turi 27, 70013 Castellana Grotte, Italy"}
{"text": "Scientific Reports 10.1038/s41598-018-28906-9, published online 13 July 2018Retraction of: The Editors have retracted this Article.1;In Fig\u00a02C the \u201cSiHa-23\u201d group appears to partially overlap with Fig\u00a02C \u201cA19\u201d group in2;In Fig\u00a04D the \u201cFibulin-3 cDNA, HeLa-25\u201d group appears to be rotated and partially overlaps with Fig\u00a03C \u201cU-2OS\u201d group inIn Fig\u00a08B the \u201cN-cadherin\u201d group  appears to partially overlap with Fig\u00a08C \u201cVimentin\u201d group .After publication of this Article it was brought to the Editors\u2019 attention that some of the images appear to overlap with those in other published articles partially from the same author group, where the data is partially attributed to different samples. Specifically:The Editors reached out to the Authors to request raw data. The Authors provided the data which did not address the concerns. The Editors therefore no longer have confidence in the results presented in this Article.Juan Li, Chen Qi, Xia Liu, Changzhong Li, and Jie Chen did not respond to the correspondence about this retraction. Min Shi did not state explicitly whether they agree to or disagree with this retraction."}
{"text": "There was a typographical error in the original publication . A correThe authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "For panel O, data were taken from other PCR experiments. While the authors have reproduced and confirmed the data for panel O, given the circumstances, they believe that the most responsible course of action is to retract the paper. The authors sincerely apologize to the scientific community for any inconvenience resulting from the publication and retraction of this manuscript.This article has been retracted at the request of the authors. This paper reported a role for Slit-Robo signaling in the control of axon guidance during peripheral nerve regeneration. The first author has admitted, orally and in writing, to the fabrication of data, unknown to other authors, and is solely responsible for this fabrication. Based on reports from the scientific community, the authors began an investigation of data and procedures in the paper. They concluded that the paper contains fabrications of data in Figure\u00a02, panels K and O. For panel K, the image for Robo2 was copied from another publication by the first author (Figure\u00a012 of Carr et\u00a0al., 2017,"}
{"text": "In the published publication, there was an error regarding the affiliation for \u201cTomoya Suzuki\u201d. In addition to affiliation \u201c2\u201d should be \u201cSchool of Medicine, Akita University, 1-1-1 Hondo, Akita 0108543, Japan\u201d. The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. The original publication has also been updated ["}
{"text": "Biomaterials Research (2023) 27:6410.1186/s40824-023-00402-wThe authors regret to report the grant number \u201c21871180\u201d in the original article [1] should instead state \u201c81872121\u201d."}
{"text": "Tremor and Other Hyperkinetic Movements: 2019; 9(0). DOI: https://doi.org/10.5334/tohm.464.This article details a correction to: Depienne C, Ciura S, Trouillard O, Bouteiller D, Leit\u00e3o E, Nava C, et al. Association of Rare Genetic Variants in Opioid Receptors with Tourette Syndrome.  This is a correction to the article \u201cAssociation of Rare Genetic Variants in Opioid Receptors with Tourette Syndrome\u201d . The ack\u201cThe authors thank the French Association for Tourette Syndrome (AFSGT) for their generous financial support\u201d.This correction was brought to the attention of the journal by the author Andreas Hartmann.The authors have no competing interests to declare."}
{"text": "Artemisia Extracts and Artemisinin-Based Antimalarials for COVID-19 Management: Could These Be Effective Antivirals for COVID-19 Treatment?\u201d [The journal retracts the article \u201cFollowing publication, concerns were brought to the attention of the Editorial Office regarding significant overlap with a previously published work  with a dMolecules, as well as the lack of methodology that differentiates the current results from previous publications. This article is therefore retracted.Adhering to our complaint\u2019s procedure, an investigation was conducted by the Editorial Office and Editorial Board and confirmed the overlap, which included a number of identical sequences of references, abbreviations not commonly used in Molecules. This retraction was approved by the Editor in Chief of the journal The authors disagree with this retraction."}
{"text": "In \u2018Understanding multiple timescale adaptation as fractional differentiation\u2019 subsection of the Results, there is an error in the equation on page 6. Please view the complete, correct equation here:D\u03b1f(x)"}
{"text": "I agree with the authors that oldhamite could have been involved as a transient phase in important geological processes [Oldhamite . ThisConflict of interest statement. None declared."}
{"text": "We believe that there were errors in the original experiment, resulting in the errors of experimental data. The relationship between ZEB1-AS1, BMP7, and miR216a-5p is uncertain\u201d.The Editors requested the authors to provide additional information regarding the inconsistencies found in the study. However, the authors presented no further details on that issue. Considering the inaccurate data and experimental deviation detected, the Editors agreed with and endorsed the decision to retract the paper.The Brazilian Journal of Medical and Biological Research had received authorization from all authors before the publication of the original paper."}
{"text": "In \u201cPerformance of a Web-Based Reference Database With Natural Language Searching Capabilities: Usability Evaluation of DynaMed and Micromedex With Watson\u201d  the authors noted two errors.1. The Authors Contributions section currently reads as:All authors contributed to the study conception; design; and acquisition, analysis, or interpretation of the data. AR, PMG, AS, LAV, DLS, GPJ, and DWB were responsible for study conception or design. PMG, HHE, DLS, and MGA developed the interview guides. MM, AS, SD, and LPN conducted participant recruitment. PMG acted as the interview moderator and had either AR or MM assisting with data collection during testing. PMG, MM, JC, and SD abstracted the data from interview recordings. Data analysis was performed by PMG, MM, and AR. The first draft of the manuscript was written by AR and PMG, with all authors reviewing the draft and providing critical feedback. All authors contributed to and approved the final manuscript.And will be changed to:RR and DWB are co-senior authors and contributed equally.All authors contributed to the study conception; design; and acquisition, analysis, or interpretation of the data. AR, PMG, AS, LAV, DLS, GPJ, and DWB were responsible for study conception or design. PMG, HHE, DLS, and MGA developed the interview guides. MM, AS, SD, and LPN conducted participant recruitment. PMG acted as the interview moderator and had either AR or MM assisting with data collection during testing. PMG, MM, JC, and SD abstracted the data from interview recordings. Data analysis was performed by PMG, MM, and AR. The first draft of the manuscript was written by AR and PMG, with all authors reviewing the draft and providing critical feedback. All authors contributed to and approved the final manuscript.2. In the original article, the ORCID number for Petra Schultz was reported as follows:0000-0001-7337-1046And has been updated to:0000-0001-7949-9243The correction will appear in the online version of the paper on the JMIR Publications website on May 18, 2023, together with the publication of this correction notice. Because this was made after submission to PubMed, PubMed Central, and other full-text repositories, the corrected article has also been resubmitted to those repositories."}
{"text": "Prevalence of active trachoma infection and associated factors post\u2010war resettled population in raya kobo districts, North East Ethiopia: A community\u2010based cross\u2010sectional study in 2022. F. Kebede, M. Jamal. Health Science Reports. 2023. 10.1002/hsr2.1486.]Retraction: [wileyonlinelibrary.com), has been retracted by agreement between the journal's Editor\u2010in\u2010Chief, Dr Charles Young, and John Wiley & Sons, Inc. The retraction has been agreed due to major overlap with a previously published article from the same group of authors.The above article, published online on 06 August 2023 in Wiley Online Library ("}
{"text": "Graft versus host disease (GVHD) is an immunologically mediated condition seen in allogeneic hematopoietic stem cell transplant (HSCT) recipients. Because of the rarity of the disease, nonspecific presentation, and lack of clinicopathological correlation, its diagnosis is often delayed and prompt treatment is deferred, with increased mortality. Extensive acute cutaneous GVHD. InitialPatient was treated with oral methylprednisolone 5\u2009mg twice daily tapered over 3\u2009weeks and maintained with Tacrolimus 1\u2009mg twice daily for 6\u2009months, along with cotrimoxazole, valganciclovir, ursodeoxycholic acid for cholestasis, and sodium chloride tablet for hyponatremia. Topical mometasone furoate ointment was locally applied over erosion of the glans penis twice daily for 2\u2009weeks with healing of lesion post treatment. The involved cutaneous and penile erosion healed over 3\u2009weeks with normal underlying skin devoid of any pigmentation or scarring Figure\u00a0. New les3GVHD is an immunologically mediated condition with varied systemic, cutaneous, and mucosal clinical features. It occurs mostly in allogeneic HSCT recipients, due to T\u2010cell\u2010mediated cytotoxicity.aGVHD is treated with oral or intravenous corticosteroid, in dose of 1\u2009mg/kg twice daily, in tapering dose, along with prophylactic maintenance with calcineurin inhibitor such as tacrolimus or cyclosporine. Corticosteroid\u2010resistant cases can be alternatively treated with immunosuppressant such as mycophenolate mofetil, tumor necrosis factor alpha inhibitors, Janus kinase inhibitor (JAK inhibitor) such as ruxolitinib or commercially available mesenchymal stem cell product.GVHD, due to its varied presentation, is difficult for clinicians to diagnose, which can lead to unforeseen complications including mortality.4This material is the authors' own original work, which has not been previously published elsewhere.The paper is not currently being considered for publication elsewhere.The paper reflects the authors' own research and analysis in a truthful and complete manner.The paper properly credits the meaningful contributions of coauthors and coresearchers.The results are appropriately placed in the context of prior and existing research.All sources used are properly disclosed (correct citation). Literally copying of text must be indicated as such by using quotation marks and giving proper reference.All authors have been personally and actively involved in substantial work leading to the paper, and will take public responsibility for its content.The authors assure that the following are fulfilled:The violation of the Ethical Statement rules may result in severe consequences.To verify originality, this article may be checked by the originality detection software.The authors agree with the above statements and declare that this submission follows the policies of Clinical Case Reports as outlined in the Guide for authors and in the Ethical Statement.Date: 5/9/2023.prazol.Corresponding author's signature: 5The authors have confirmed that patient consent has been signed and collected in accordance with the journal's patient consent policy.The authors agree with the above statements and declare that this submission follows the policies of Clinical Case Reports as outlined in the Guide for authors and in the Ethical Statement.Date: 5/9/2023.prazol.Corresponding author's signature: Prajwal Pudasaini: Conceptualization; supervision; visualization. Sushil Paudel: Conceptualization; project administration; resources; writing \u2013 original draft; writing \u2013 review and editing. G.C Sagar: Conceptualization; supervision. Sadiksha Adhikari: Conceptualization; visualization. Neeraj Thapa: Investigation. Bibechan Thapa: Conceptualization; visualization.None.None.The authors declare that this submission follows the policies of Clinical Case Reports as outlined in the Guide for authors and in the Ethical Statement.Written informed consent was obtained from the patient to publish this report in accordance with the journal's patient consent policy."}
{"text": "RSC Advances article and ref. The authors regret unattributed data overlap between their The SEM data in Fig. 1a of this article was re-used from ref. The authors have now received the permission to reuse the images and the corrected caption is shown below:Fig. 1 SEM micrographs of (a) and (b) uncoated scaffolds, (c)\u2013(f) cellulose nanowhiskers coated scaffolds, (g) cellulose nanowhiskers at different magnifications and (h) cellulose nanowhiskers coated scaffolds after immersion in SBF for 1 day. Reproduced in part from Wei Li et al., J. Mech. Behav. Biomed. Mater., 2014, 40, 85\u201394 with permission from Elsevier.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Martin et al., RSC Chem. Biol., 2023, https://doi.org/10.1039/D3CB00020F.Correction for \u2018Radiolabeling and  The authors regret the omission of a funding body associated with the work. J. A. M. and J. A. C. acknowledge funding from the US Department of Energy (DE-SC-0021007 to J. A. C.).The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "In \u201cRacial/Ethnic Disparity in Association Between Fetal Alcohol Syndrome and Alcohol Intake During Pregnancy: Multisite Retrospective Cohort Study\u201d  the authors noted one error.The authorship was previously published as:Sarah Soyeon Oh, SangMin Kim, Bada Kang, Jewel Park, Seung Hee Lee, Eun-Cheol Park, Ichiro KawachiAnd will be changed to read as follows:Sarah Soyeon Oh, Bada Kang, Jewel Park, SangMin Kim, Eun-Cheol Park, Seung Hee Lee, Ichiro KawachiThe correction will appear in the online version of the paper on the JMIR Publications website on April 28, 2023 together with the publication of this correction notice. Because this was made after submission to PubMed, PubMed Central, and other full-text repositories, the corrected article has also been resubmitted to those repositories."}
{"text": "In the original publication , errors For Figure 4A\u2013F, the blots of samples ctrl, BCP 50, and BCP 100 for the targets Bcl2, Bax, Caspase 3, Cyclin D1, and the \u03b2 actins are re-analyzed. All of the blot images and integrated intensity are updated for the figure. For Figure 7, the blots of samples ctrl, BCP 50, and BCP 100 for the targets Cyclin D1 and the \u03b2 actins are re-analyzed. The subfigures C and F are updated with the new information.It was confirmed that the study\u2019s original conclusions are still valid and unchanged. The corrected The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "A remote group-mediated daylong physical activity intervention for older adults with chronic pain: Results of the MORPH-II randomized pilot trial By Fanning J, Brooks AK, Ford S, Robison JT, Irby MB and Rejeski WJ. (2022). Front. Digit. Health 4:1040867. doi: 10.3389/fdgth.2022.1040867An erratum on Due to a production error, the reference list in the published paper was missing some citations and did not reflect the authors' corrected manuscript.The publisher apologizes for this mistake.The original version of this article has been updated."}
{"text": "The journal retracts the 9 January 2018 article cited above.Following publication, concerns were raised regarding the integrity of the images in the published figures, with areas of image duplication in Figure 3E. The authors failed to provide a satisfactory explanation during the investigation, which was conducted in accordance with Frontiers' policies. As a result, the data and conclusions of the article have been deemed unreliable and the article has been retracted.This retraction was approved by the Chief Editors of Frontiers in Molecular Neuroscience and the Chief Executive Editor of Frontiers. The authors did not agree to this retraction."}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors\u2019 attention by a concerned reader that certain of the cell migration and invasion assay data shown in Figs. 2C and 5C were strikingly similar to data appearing in different form in other articles by different authors at different research institutes. Owing to the fact that the contentious data in the above article were already under consideration for publication prior to its submission to"}
{"text": "Study to compare the effect of casirivimab and imdevimab, remdesivir, and favipiravir on progression and multi-organ function of hospitalized COVID-19 patients Open Medicine 2023;18(1):20230768, DOI: Journal of Clinical Virology Plus: doi.org/10.1016/j.jcvp.2023.100151.Editorial Office decided to retract this article due to significant overlap with the other papers published by the same authors in"}
{"text": "The journal retracts the 24 March 2020 article cited above.Following publication, concerns were raised regarding the integrity of the images in the published figures, with areas of image duplication and manipulation in Figures 5, 6. The authors failed to provide a satisfactory explanation during the investigation, which was conducted in accordance with Frontiers' policies. As a result, the data and conclusions of the article have been deemed unreliable and the article has been retracted.This retraction was approved by the Chief Editors of Frontiers in Molecular Neuroscience and the Chief Executive Editor of Frontiers. The authors did not agree to this retraction."}
{"text": "To the Editor,Liao et al.All authors verify their contribution to the production and writing of this manuscript.The authors declare no conflict of interest."}
{"text": "They also apologize to the readership for any inconvenience caused.The authors have re-examined their original data, and realize which data panel should have been included for this experiment in this figure. The corrected version of"}
{"text": "The authors wish to make the following corrections to this paper .In the published version, the resection rate numbers as reported by Kok et al.  were citThe sentence \u201cAmong patients operated on for LRRC, R0 resection rate using surgical navigation was 21% compared with 51% in a case control group\u201d should be changed to \u201cAmong patients operated on for LRRC, R0 resection rate using surgical navigation was 79% compared with 49% in a case control group\u201d.The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "In the original publication , there wThe authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "EquatioA correction has been made to Section 2. Methods, Section 2.4. Optical Parameter Model, Equation (1). The correct equation is:The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "In the original publication , there wThe authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "Retraction Note: BMC Pharmacol Toxicol\u00a020, 57 (2019)https://doi.org/10.1186/s40360-019-0335-5The Editor has retracted this article. After publication, concerns were raised regarding high similarity between the images presented in Fig.\u00a011 of this article and Fig.\u00a06 in the authors' earlier work\u00a0[None of the authors have responded to correspondence from the Editor about this retraction notice."}
{"text": "Scientific Reports 10.1038/s41598-023-31355-8, published online 15 March 2023Correction to: The original version of this Article contained errors in the Author contributions and Acknowledgements sections.The Author Contributions section,\u201cD.J.: formal analysis, methodology, software, data collection, validation, visualization, conceptualization, writing\u2014original draft, writing\u2014reviewing and editing. H.W.: investigation, funding acquisition, conceptualization, resources, project administration and supervision. J.C.: data curation. C.D.: visualization.\u201dnow reads:\u201cD.J.: formal analysis, methodology, software, data collection, validation, visualization, conceptualization, writing\u2014original draft, writing\u2014reviewing and editing. H.W.: investigation, conceptualization, resources, project administration and supervision. J.C.: data curation. C.D.: visualization and funding acquisition.\u201dIn addition, the digit of the Project Code in the Acknowledgements section was incorrect.\u201cThe authors received the support from The National Key R&D Program of China (2021YFF0306405). The authors appreciate the funding organization for their financial supports. The authors would also like to thank the Baiqingzhai ski resort in Shenyang of China for its full support.\u201dnow reads:\u201cThe authors received the support from The National Key R&D Program of China (2021YFF0306400). The authors appreciate the funding organization for their financial supports. The authors would also like to thank the Baiqingzhai ski resort in Shenyang of China for its full support.\u201dThe original Article has been corrected."}
{"text": "Dis. Model. Mech. (2015) 8, dmm017624 (doi:10.1242/dmm.017624).An error was noted in The authors inadvertently transposed the mouse and human hepatocellular carcinoma (HCC) panels in Fig.\u00a03E during figure assembly. The corrected figure panel is shown below.Furthermore, the bottom-right image in Fig.\u00a03D (\u2018Tumor \u2013 15\u2019) and the mouse HCC image in Fig.\u00a03E were acquired from the same tumor sample under different imaging conditions. The legend for Fig.\u00a03E has been updated to reflect this.This Correction does not affect the results in the article or the conclusions of this study. The authors apologise for the error and any inconvenience it may have caused."}
{"text": "When this article was originally published in Psychological Medicine it omitted an acknowledgment credit. This section has been updated to include the following: \u2018The authors also grateful acknowledge research assistant Qiao Ying Leong and research fellow Dr. Alexandria Marie Remus of the N.1 Institute for Health and WisDM for their work in Prospero registration/literature review framework guidance, and literature review.\u2019.The authors apologise for this error."}
{"text": "This is a topic with controversial and opposing views in the literature which we would have loved to see the authors point out so as to have a balanced discussion.,We have read Kaggwa et\u00a0al.\u2019sWe are not aware of any evidence for the claims that LME is a prolonged process that takes months to years of physical and mental suffering. We could not find epidemiological studies comparing any form of distress or mental disorders between those who practice LME and those who do not.In many African cultures, LME is considered a symbol of femininity and cultural identity.All authors contributed equally to this letter.All authors have no interests to disclose."}
{"text": "The authors wish to make the following corrections to this paper: .There was a mistake in Figure 3 as published. Figure 3c must be substituted with the following one. The corrected The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "It should read \u201cnitric acid solution \u201d. On line 4 in the \u201c3.1 Characterization of AuNPs\u201d section, on page 15088 of the original article, the text originally read \u201cobserved by TEM at 20KX, 50KX and 100KX magnifications\u201d. It should read \u201cobserved by TEM at 30KX, 50KX and 100KX magnifications\u201d.The authors regret that there were errors that appear in sections \u201c2.5 SERS measurements\u201d and \u201c3.1 Characterization of AuNPs\u201d. On line 3 in the \u201c2.5 SERS measurements\u201d section, on page 15087, the text originally read \u201cnitric acid solution \u201d should be changed to \u201cband(s)\u201d, and \u201cexperimental Raman\u201d should be changed to \u201cexperimental SERS\u201d throughout the text.In the original article, the authors regret that the incorrect caption was given for Fig. 4. The corrected caption for Fig. 4 is given below.Fig. 4 Theoretical Raman and experimental SERS of four colorants and their molecular structures. (A and B) Erythrosine, (C and D) basic orange 2, (E and F) basic orange 21, and (G and H) basic orange 22. The red curve represents the theoretical Raman spectra, and black denotes the experimental SERS.a vibration modes: \u03bd, stretching; \u03b4, in-plane deformation.\u201dThe authors regret that there is an error in the footnote of Tables 1\u20134. The correct footnote should read \u201cThe authors regret that a wrong value was given in Table 6 for the FDDY-basic orange 21 mixture's REP (%). The correct value should be 5.85.The authors also regret that incorrect details were given for ref. 1 and 41 in the original article. The correct versions of ref. 1 and 41 are given below as ref. The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Scientific Reports 10.1038/s41598-021-01931-x, published online 30 November 2021Retraction of: The Editors have retracted this article.After publication concerns were raised that the XRD spectra in Fig.\u00a08 are identical. The authors are unable to provide the original data for examination. In addition, an investigation by the Editors has shown inappropriate changes in authorship during the review process. The Editors no longer have confidence in the results and conclusions presented.Jawad Ahmad disagrees with this retraction. Fahid Aslam and Mohamed Hechmi El Ouni did not respond to correspondence from the Editors about this retraction. The Editors were not able to obtain current email addresses for Rebeca Martinez-Garcia and Khalid Mohamed Khedher."}
{"text": "Correction to: Graefe\u2019s Archive for Clinical and Experimental Ophthalmology (2021) 259:3511\u2013351310.1007/s00417-021-05217-wWe revised Table 1 after a change in methodology prior to submission, but erroneously left the table headers of Table 1 from the first data run. The remainder of the data within the manuscript and table are accurate.This erratum would like to correct the column headers of Table 1 as:Total population , APPM , MPM , CPM , IHM .We apologize for this error."}
{"text": "Furthermore, they apologize to the readership for any inconvenience caused.The authors have re-examined their data and realized that Fig. 5A was inadvertently assembled incorrectly; however, the authors still had access to their original data, and the revised version of Fig. 5, now including the correct data panel for the \u2018hUMSCs/vector\u2019 experiment, is shown opposite. The authors regret the error that was made during the preparation of this figure, although they were able to confirm that this did not seriously affect the conclusions reported in the paper. The authors are grateful to the editor of"}
{"text": "The funder Avalon Globo-Care Corp had no interference in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript, or in the decision to publish the results. The authors apologise for this error.In the aforementioned article, the authors\u2019 conflict of interest statement is incorrectly worded. The statement should read:"}
{"text": "The Royal Society of Chemistry is publishing this Expression of concern in order to alert readers that concerns have been raised regarding the reliability of the SEM data in Fig. S1b and d. An investigation is underway, and an Expression of concern will continue to be associated with the article until a final outcome is reached.Laura Fisher2nd November 2023RSC AdvancesExecutive Editor,"}
{"text": "Sci., 2022, 13, 1263\u20131269, https://doi.org/10.1039/D1SC04502D.Correction for \u2018Peptide epitope-imprinted polymer microarrays for selective protein recognition. Application for SARS-CoV-2 RBD protein\u2019 by Zs\u00f3fia Bogn\u00e1r  The authors regret that the funding details were incomplete in the Acknowledgements section of the original article. In addition to the original acknowledgements the following text should have been included:The research reported in this paper is part of Project BME-EGA-02, implemented with support provided by the Ministry of Innovation and Technology of Hungary from the National Research, Development and Innovation Fund, financed under the TKP2021 funding scheme.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "In addition, for the images shown in Figures\u00a02D and S2F, the MGM concentration used was 10-fold higher than originally described, and there were minor differences in the staining and washing steps. All these differences have since been corrected online. All co-authors on the manuscript have approved these corrections. The authors apologize for the error."}
{"text": "Correction: Hereditas (2021) 158:1010.1186/s41065-021-00171-3Following the publication of the original article , the comDr. Yongyong Shi is a Chief Scientist for Dynegene and a Co-Chief Editor for Hereditas. All the other authors declare that they have no competing interests."}
{"text": "Although there are more women in medicine now than ever before, gender parity is still not reflected in leadership positions within academic medicine , 2. ArtiAll research articles published online in the journal were analyzed from 2013 to the end of 2021. The genders of first, middle and senior authors were recorded along with the article type, article category and institutional affiliations. The total number of female authors including unique authors, along with the number of first and senior female authors specifically, were quantified. Gender was identified through name searches and online sources. Proportions of same-gender first and senior authors were calculated. Cochran-Armitage trend tests were used to assess the change in proportion over time between years and groups. Chi-square tests of gender differences were used to assess gender representation by article category and type. The study used publicly available, de-identified data and was exempt from institutional ethics board review.P\u2009<\u20090.001). Of the 529 first authors, 157 (29.7%) were female and 372 (70.3%) were male (P\u2009<\u20090.001). Of the 521 senior authors, 74 (14.2%) were female and 447 (85.8%) were male (P\u2009<\u20090.001)  female authors and 2331 (76.2%) male authors (P\u2009=\u20090.298) and senior authors  did not increase significantly over time. The proportion of articles with same gender first and senior author by year revealed a non-significant decrease in male first author to male senior author collaborations . There was a significant difference in gender representation in senior authorship by article category, notably in facial plastics and rhinology (P\u2009=\u20090.005) (Table The proportion of female first authors (25.4% in 2013 to 35.7% in 2021; Journal of Otolaryngology Head and Neck Surgery. These findings suggest that female OHNS surgeons are participating in research overall at similar rates at which they are represented in the Canadian OHNS community [The present study highlights the trends in female authorship representation within the Canadian ommunity . Despiteommunity .Although there has been an increase in the proportion of female authors in the Canadian Journal, our findings suggest that there is no significant change in female authorship representation throughout the study period. By leveraging quantitative findings, future studies should identify barriers to female advancement within the field and encourage actionable efforts such as promotion of women in academia and diversification of research opportunities. In doing so, we will be able to dismantle the hurdles and encourage sponsorship of female OHNS surgeons in their academic contributions to the field."}
{"text": "The full text of this preprint has been withdrawn by the authors while they make corrections to the work. Therefore, the authors do not wish this work to be cited as a reference. Questions should be directed to the corresponding author."}
{"text": "Correction to: Cancer Immunology, Immunotherapy (2023) 72:193\u2013209 10.1007/s00262-022-03227-zThe original version of this article unfortunately contained a mistake. There were two mistakes in the Figs.\u00a0In Fig.\u00a02 amendments are:Fig. 2a\u2013b: Y-axis label,Fig.\u00a02a: Fig. 2a is wrong, it is the content of Fig.\u00a02c, we modified this figure.In Fig.\u00a05 amendments are:Fig. 5c: Statistical results are blocked.The corrected Figs."}
{"text": "Cabeza et al., Chem. Sci., 2023, https://doi.org/10.1039/D3SC02709K.Correction for \u2018Fast and scalable solvent-free access to Lappert's heavier tetrylenes E{N(SiMe The originally published \u03b7solv = 1* , was omitted.In In The updated The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Oncogene 10.1038/s41388-021-02009-8, published online 29 September 2021Correction to: The authors have become aware of an error in Figure 6B, where the histological image assigned to R304Q was from the same animal as the image marked C238Y. The authors have provided the corrected figure below. This correction has no impact on the results or conclusions presented in this paper.The authors apologize for the error and regret any inconvenience this may have caused for the readers.The original article has been corrected."}
{"text": "In the Research Article \u201cTumor Microenvironment-Specific Chemical Internalization for Enhanced Gene Therapy of Metastatic Breast Cancer,\u201d the authors made an error in Fig."}
{"text": "Journal of Molecular Cell Biology (2017), 9(4), 289\u2012301, https://doi.org/10.1093/jmcb/mjx022In this article, there were errors in Figures 4D , 3E and F, 5G and H, and 5J and K .Iba1 band in Figure 4D was the same as Cleaved caspase-3 band in Figure 2F. This was caused by carelessly mistaking the latter  for Iba1 band due to the high similarity between images . This was caused by carelessly using the same FCS file for analyzing different groups, which was not immediately discovered by authors due to the similar percentage values and shapes as expected from the two groups. All the re-exported FACS images from re-analyzing the original FCS files by Flowjo software are provided in the Journal of Molecular Cell Biology online.These corrections do not affect the results, discussion, or conclusions. The authors sincerely apologize to the editors and readers for any inconvenience or confusion. Figure 4DFigure 3E and FFigure 5G and HFigure 5J and Kmjad028_Supplemental_FileClick here for additional data file."}
{"text": "Please find the retraction statement below:Following publication, concerns were raised regarding the integrity of the images in the published figures.Following the provision of raw data by the authors, the Chief Editor concluded that the article\u2019s conclusions and assertions were not sufficiently supported by the findings from the material provided; therefore, the article has been retracted.This retraction was approved by the Chief Editor of Frontiers in Oncology and the Chief Executive Editor of Frontiers."}
{"text": "Following the publication of this article , concernThe University of California, Davis confirmed that author DPW admitted to manipulation of the data underlying the results presented in Figs 6 and 7.PLOS Genetics Editors issue this Expression of Concern to notify readers of the above issues.The authors are working with PLOS to try and address these issues. Meanwhile, the"}
{"text": "Error in FigureIn the original publication , there wThe authors state that the scientific conclusions are not affected by this correction. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "Acta Cryst. (2022), B78, 643\u2013664] are given.Corrections to the article by K\u00f6nig and Smith [ Acta Cryst. (2022), B78, 643\u2013664Corrections to the article by K\u00f6nig and Smith [ Acta Cryst. (2022), B78, 643\u2013664h and interface lengths dIF. In addition, the caption of Fig. 13 wrongly mentions {110} instead of In the paper by K\u00f6nig & Smith [The authors apologize for inconveniences caused by the misprints."}
{"text": "The published version of this paper listed onlyRobert Freer asthe corresponding author. The purpose of this correction is to identifyboth David J. Lewis and Robert Freer as corresponding authors.The conclusions of the work have not been affected by this correction."}
{"text": "In Vitro Assay to Evaluate Treatment Resistance in Patients Receiving Immunosuppressive Therapy\u201d published on 25 January 2021. Specifically, concerns have been raised that three individuals, Veronica S\u00e1nchez Rodr\u00edguez, Marianna di Scala, and Javier Dotor, have been excluded from the author list. An investigation was conducted in line with COPE guidelines involving the authors\u2019 institution and the funding body, but unfortunately no conclusion could be reached.With this notice, Frontiers states its awareness of concerns regarding the authorship of \u201cThe Immunobiogram, a Novel This Expression of Concern was approved by the Chief Editors of Frontiers in Immunology and the Chief Executive Editor of Frontiers. The authors do not agree to this Expression of Concern."}
{"text": "Dis. Model. Mech. (2010) 3, dmm002311 (doi:1242/dmm.002311).There were errors in SREBP-1c, ACC1, FAS, PPARA, CPT1, ACO1 and \u03b2-actin shown in the original Fig.\u00a03E and Fig.\u00a04E represent cropped images of a single set of gels. However, during figure assembly, some images were cropped incorrectly, leading to discrepancies among the images shown.All semi-quantitative RT-PCR data for SREBP-1c , FAS , CPT1  and \u03b2-actin  gels. The authors have provided the corrected versions of these panels as a single figure. All citations to Fig.\u00a03E and Fig.\u00a04E in the main text should now refer to this new panel.Specifically, there were errors in assembly of the This correction does not affect the results in the article or the conclusions of this study. The authors apologise for these errors and any inconvenience they may have caused."}
{"text": "Genetics, 2023, iyad049, https://doi.org/10.1093/genetics/iyad049This is an Editor's Note on: This Version of Record incorporates edits made by the authors prior to manuscript acceptance in response to reviewer feedback, but that were not included in the version that posted as an Accepted Manuscript. The authors, editors, and publisher apologize for any confusion caused to readers."}
{"text": "Furthermore, the data panels shown in Fig. 3A for the \u2018Control/U343\u2019 and \u2018Control/172\u2019, and the \u2018miR-21/\u03b2-catenin\u2019 and \u2018Control/T98\u2019, experiments were also found to be unexpectedly similar, given that these were likewise intended to show the results from differently performed experiments.Molecular Medicine Reports has determined that the above paper should be retracted from the Journal on account of a lack of confidence in the presented data. The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a satisfactory reply. The Editor regrets any inconvenience that has been caused to the readership of the Journal.After having conducted an independent investigation in the Editorial Office, the Editor of"}
{"text": "Corrigendum on:Impact of a tobacco sales ban on the frequency of tobacco consumption in India during the COVID-19 pandemicBy Nitika Sharma, Mansi Chopra, Linda Bauld, Gaurang P. Nazar, Nishigandha Joshi, Aastha Chugh, Sailesh Mohan, Deepa Mohan, Mohammed K. Ali, Vishwanathan Mohan, Nikhil Tandon, K. M. Venkat Narayan, K. Srinath Reddy, Dorairaj Prabhakaran, Monika AroraTobacco Induced Diseases, Volume 21, Issue April, Pages 1\u20136, Publish date: 28 April 2023https://doi.org/10.18332/tid/161855DOI: In the originally published version of the article, the name of the 12th author was given as Venkat K. M. Narayan and is now changed to K. M. Venkat Narayan. Furthermore, in the authors\u2019 contributions section, the initials VKMN are now changed to KMVN. The mentioned changes are corrected also online."}
{"text": "Cancer Med. 2019;8:4782\u20134791. https://doi.org/10.1002/cam4.2350Tong L, Ao Y, Zhang H, Wang K, Wang Y, Ma Q. Long noncoding RNA NORAD is upregulated in epithelial ovarian cancer and its downregulation suppressed cancer cell functions by competing with miR\u2010155\u20105p. wileyonlinelibrary.com), has been retracted by agreement between the authors, the journal Editor in Chief, Dr Stephen Tait and John Wiley and Sons Ltd. The retraction has been agreed due to scientific inconsistences invalidating the conclusions presented.The above article, published online on 28 June 2019 in Wiley Online Library ( Cancer Med. 2019;8:4782\u20134791. https://doi.org/10.1002/cam4.2350Tong L, Ao Y, Zhang H, Wang K, Wang Y, Ma Q. Long noncoding RNA NORAD is upregulated in epithelial ovarian cancer and its downregulation suppressed cancer cell functions by competing with miR\u2010155\u20105p. wileyonlinelibrary.com), has been retracted by agreement between the authors, the journal Editor in Chief, Dr Stephen Tait and John Wiley and Sons Ltd. The retraction has been agreed due to scientific inconsistences invalidating the conclusions presented.The above article, published online on 28 June 2019 in Wiley Online Library ("}
{"text": "Moreover, it appeared that various of the data shown in this figure, and western blotting data shown in Fig. 3A, were strikingly similar to data that had appeared in different form in different articles published by different authors at different research institutes.Experimental and Therapeutic Medicine, the Editor has decided that this paper should be retracted from the Journal. The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Owing to the fact that some of the data in the above article had already been published, or were under consideration for publication, prior to its submission to"}
{"text": "Dear Editor, we would like to share ideas on the publication \u201cStroke seven hours after SARS-CoV-2 vaccination\u201d.The authors declare no conflicts of interest."}
{"text": "In the original publication , the figThe original References [142\u2013145] should be moved after Reference [62], listed as References [63\u201366]. With this correction, the order of some references has been adjusted accordingly. The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "AIDS Research and Therapy (2023) 20:3310.1186/s12981-023-00531-1The Editor-in-Chiefs have retracted this article because it contains material that substantially overlaps with the following articles (amongst others) , 2. None"}
{"text": "NQO1 promotes an aggressive phenotype in hepatocellular carcinoma via amplifying ERK\u2010NRF2 signaling. Cancer Sci. 2021; 112: 641\u2013654. wileyonlinelibrary.com), has been retracted by agreement between the authors, the journal's Editor\u2010in\u2010Chief, Masanori Hatakeyama, the Japanese Cancer Association and John Wiley and Sons Australia, Ltd. The retraction has been agreed following concerns raised by a third party about figures within the article. During the journal's investigation into the concerns raised, the authors were not able to provide comprehensive original data for the figures in concern. Accordingly, the editorial team considers the conclusions of this manuscript insufficiently supported.The above article, published online on 22 November 2020 in Wiley Online Library ( NQO1 promotes an aggressive phenotype in hepatocellular carcinoma via amplifying ERK\u2010NRF2 signaling. Cancer Sci. 2021; 112: 641\u2013654. wileyonlinelibrary.com), has been retracted by agreement between the authors, the journal's Editor\u2010in\u2010Chief, Masanori Hatakeyama, the Japanese Cancer Association and John Wiley and Sons Australia, Ltd. The retraction has been agreed following concerns raised by a third party about figures within the article. During the journal's investigation into the concerns raised, the authors were not able to provide comprehensive original data for the figures in concern. Accordingly, the editorial team considers the conclusions of this manuscript insufficiently supported.The above article, published online on 22 November 2020 in Wiley Online Library ("}
{"text": "Withdrawal: https://onlinelibrary.wiley.com/doi/10.1002/npr2.12343 ), has been withdrawn by agreement between the authors, the journal Editor in Chief, Tsuyoshi Miyakawa and John Wiley & Sons Australia, Ltd. The Withdrawal has been agreed because the patient revoked consent to the publication.The above article, published online on 07 May 2023 in Wiley Online Library (wileyonlinelibrary.com) as Early View ("}
{"text": "Scientific Reports 10.1038/s41598-021-94450-8, published online 29 July 2021Retraction of: The Editors have retracted this Article.Following publication, concerns were raised about the rationale for the approach presented, the assumptions and approximations used and the validity of its application to cardiology. A post-publication review of the Authors' mathematical arguments revealed a lack of clarity in the terms presented and inferences that are not adequately justified. The main concerns are that the model is based on circular reasoning which makes it non-predictive, that it assumes that blood behaves as an ideal gas, and hypothesizes that quasi-sonic flow velocities exist in the cardiovascular system while all experimental evidence shows that cardiovascular flow velocities are orders of magnitude lower than the speed of sound and do not involve any compressibility effects. The Editors therefore no longer have confidence in the conclusions presented.None of the Authors has responded to correspondence from the Editors about this retraction."}
{"text": "Sci., 2019, 10, 2067\u20132074, https://doi.org/10.1039/C8SC02847H.Correction for \u2018A non-sacrificial method for the quantification of poly(ethylene glycol) grafting density on gold nanoparticles for applications in nanomedicine\u2019 by Jun Lu  D) were incorrect. The corrected equation and calculated diffusion coefficient are shown here:The authors regret that on page 9 of the ESI, the Stokes\u2013Einstein equation and calculated diffusion coefficient  on page 2068 of the main article should therefore be 3.81 \u00d7 10The ESI available online has now been updated to reflect these changes.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Scientific Reports 10.1038/s41598-022-15685-7, published online 07 July 2022Retraction of: The Editors have retracted this Article.After publication concerns were raised about the use of nonsensical language and excessive citation of work that is not directly relevant to the subject of this article. The Editors requested an explanation from the Authors; however, their response did not adequately address these concerns. The Editors therefore no longer have confidence in the reliability of the conclusions presented.Wasim Jamshed, Mohamed R. Eid, Rabia Safdar, Amjad Ali Pasha, Siti Suzilliana Putri Mohamed Isa, Mohammad Adil and Wajaree Weera disagree with this retraction. Zulfiqar Rehman has not responded to correspondence from the Editors about this retraction."}
{"text": "The authors regret an error in the acknowledgments of the original manuscript, which has been corrected in the present corrigendum:Ministerio de Ciencia e Innovaci\u00f3n, under the grant agreement PID2019-107126RB-C22. Additionally, we would like to express our gratitude to Imefy for providing the high-density pressboard, the mechanical properties of which are reported in the present article.The authors gratefully acknowledge funding for this work from the The authors would like to apologise for any inconvenience caused."}
{"text": "There was an error in the original publication . We misuA correction has been made to Methods, Paragraph 1 on the first line:\u201cThe study was systematically reviewed following the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines [26].\u201dThe authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "In the original version, onlyBruno Ehrler is listed as a corresponding author, but both Han Zuilhofand Bruno Ehrler are corresponding authors."}
{"text": "Retraction Note: Cell Commun Signal 20, 35 (2022)https://doi.org/10.1186/s12964-022-00833-3The Editor has retracted this article on request from the authors. After publication, the authors became concerned that the KYSE180 cell line used in this study was contaminated. In addition, image overlap has been found in Fig.\u00a02F. The authors stated overlapping images for cell line KYSE30 were wrongly used to present data for cell line KYSE180. Readers should disregard this figure.Authors Han-Ming Huang, Xin-Hua He, Guo-Yun Wang, Ze-Peng Du, Qiao-Xi Xia and Yong-Fa Zhang agree to this retraction. Author Xiao-Yu Huang has not responded to correspondence from the publisher or editor about this retraction."}
{"text": "Following publication, the editorial office was contacted by the first author regarding the omission of co-authors from the article, due to a misunderstanding of their contributions. All authors of the manuscript have agreed to and requested to retract the published article.This retraction was approved by the Chief Editors of Frontiers in Veterinary Science and the Chief Executive Editor of Frontiers."}
{"text": "Correction: BMC Public Health 22, 1385 (2022)https://doi.org/10.1186/s12889-022-13724-6The original publication of this article  containeIncorrectIG, MT, MS, JP, NF, LC, FL, AK, NG, ET, PG conceptualised the project. All authors were involved with generation of the protocol. IG, MT, ATM, MS, GP and JP wrote the first draft of the manuscript. All authors listed have been implicated in the development of the ongoing project described in the protocol including patients. All authors were involved in editing and approving the manuscript. The corresponding author attests that all listed authors meet authorship criteria and that no others meeting the criteria have been omitted. IG, MT, MS, and AK act as guarantors.Correct.IG, MT, MS, JP, NF, GP,LC, FL, AK, NG, ET, PG conceptualised the project. All authors were involved with generation of the protocol. IG, MT, ATM, MS, GP and JP wrote the first draft of the manuscript. All authors listed  have been implicated in the development of the ongoing project described in the protocol including patients. All authors were involved in editing and approving the manuscript. The corresponding author attests that all listed authors meet authorship criteria and that no others meeting the criteria have been omitted. IG, MT, MS, and AK act as guarantors."}
{"text": "This is a peer-review report submitted for the paper \u201cExploring the Reasons for Low Cataract Surgery Uptake Among Patients Detected in a Community Outreach Program in Cameroon: Focused Ethnographic Mixed Methods Study.\u201dDear Authors,Thank you very much for this interesting paper  about caKind regards!"}
{"text": "Mutation of residue 313 in the viral nucleoprotein from F/L to Y/V  facilitates IAVs to escape from BTN3A3 restriction on virus replication. It is worrisome that regional migration of migratory birds, intensified livestock production, and global population mobility accelerate the cross\u2010species transmission of IAVs from other host species to humans.The spillover of avian IAVs from avian to human has caused several global pandemics, seriously affecting global economic development and threatening the health of humans and animals.H.F. designed the research. H.F., L.T., and M.L. read the papers and analyzed the data. L.T. and H.F. wrote and revised the manuscript. All authors have read and approved the final manuscript.The authors declare they have no conflicts of interest.2Not applicable."}
{"text": "Retraction Note: BMC Cancer (2022) 22:72810.1186/s12885-022-09833-5The Editors have retracted this article. After publication, the authors contacted the journal to request a correction to Fig.\u00a02c, as the same images were used for EdU si-NC and EdU si-Lnc-NDRG1, and provided the raw data for validation. Further checks by the publisher found additional concerns:Figure\u00a05d MG63 si-NDRG1\u2009+\u2009miR-96-5p inhibitor NC and si-NDRG1\u2009+\u2009miR-96-5p inhibitor images (and the associated raw data) appear to overlap.There appear to be several other instances of image overlap in the raw data files.The Editors therefore no longer have confidence in the presented data.Xi Chen, Hao Zhu, Guangxin Zhou and Zhen Wang agree to this retraction. None of the other co-authors have responded to any correspondence from the Editors about this retraction."}
{"text": "The journal retracts the 02 July 2019 article cited above.Following publication, concerns were raised regarding the integrity of the images in the published figures. The authors failed to provide the raw data or a satisfactory explanation during the investigation, which was conducted in accordance with Frontiers\u2019 policies. Given the concerns about the validity of the data, and the lack of raw data, the editors no longer have confidence in the findings presented in the article.This retraction was approved by the Chief Editors of Frontiers in Pharmacology and the Chief Executive Editor of Frontiers. The authors agree with this retraction."}
{"text": "In the original publication , there wThe authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "Retraction: J Transl Med (2019) 17:76 https://doi.org/10.1186/s12967-019-1830-6The Editor-in-Chief has retracted this article at the corresponding author's request. After publication, concerns were raised regarding the images presented in the figures. Specifically:In Fig.\u00a01d, the Control and Test images appear to originate from the same sample.Fig. 2d Control appears highly similar to Fig.\u00a02b circRNA overexpression group in the authors' other article that was under consideration within a similar time frame .In Fig.\u00a04a, the Control and Test 0h images appear to overlap.In Figs. 4b and 6b, the 0h images appear to contain overlapping areas.In Fig.\u00a04c, there appears to be an overlapping area between the SSC9 Control and Test images.In Fig.\u00a07d, based on the shapes of the bands, it appears that the caspase-3 blot is shifted by one lane, so the group labels don't seem to match the samples.The authors have checked the data underlying this article and stated that incorrect images were used. The authors and the Editor-in-Chief therefore no longer have confidence in the presented data.Wen Su, Feng Wang, Yuehong Shen and Hongyu Yang agree to this retraction. The Publisher has not been able to obtain a current email address for Shuai Sun."}
{"text": "The authors wish to make the following corrections to this paper . On page 6 of the published paper, the authors would like to correct In the original publication, there was a mistake in On page 7 of the published paper, the authors would like to correct In the original publication, there was a mistake in On page 6 of the published paper, the authors would like to correct the last sentence of Paragraph 3.5 of the Results section:There was an error in the original publication. The last sentence of Paragraph 3.5 reads: \u201cOn multivariate analysis of mortality in TV and LL cohorts, only age in the TV group and ventricular stimulation percentage in the LL group appeared to significantly impact mortality, while on analysis of the entire population, only age displayed a significant association with mortality \u201d; howeveOn page 3 of the published paper, the authors would like to correct the third paragraph of the Materials and Methods section:There was an error in the original publication: the symbol \u201c\u2264\u201d is missing from the second sentence of the third paragraph of the Materials and Methods section. A correction has thus been made to the third paragraph of Materials and Methods, as follows: \u201cSpecifically, vitamin K antagonists were tapered to the INR range of 2\u20132.5 for the week following device implantation in patients with CHA2DS2-VASc score \u2264 3.\u201dLastly, on pages 3\u20136 of the published paper, the authors would like to make the following corrections to the Results section:In the Results section (pages 3\u20136), the spelled out numbers have been changed to numerals for clarity purposes.The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "The authors would like to make the following corrections to the publication :The authors accidentally mixed up the place of the numbers 2 and 3 in the designation \u201cSLC3A2\u201d of the heterodimeric partner of LAT-1, namely CD98 (4F2hc). Therefore, on various occasions throughout the paper, we incorrectly wrote the designation as \u201cSLC2A3\u201d (which is the designation of GLUT3) instead of its correct designation \u201cSLC3A2\u201d. Throughout the whole text, including the title, citation and Figure 5 legend, the authors would like to replace \u201cSLC2A3\u201d with \u201cSLC3A2\u201d.Additionally, in Section 4.10, the cell line \u201chCMEC/D3\u201d was misspelled as \u201cHPMEC/D3\u201d.The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "Retraction to: Molecular Medicine (2018) 24:18 10.1186/s10020-018-0020-yThe Editor in Chief has retracted this article after an investigation by the Academic Committee of Jiangsu Normal University found image irregularities in Figs.\u00a03 and 4\u00a0C, 6\u00a0A and 7\u00a0C. The Academic Committee of Jiangsu Normal University requested the original experimental records and data for verification from the authors of this article, however, the authors were unable to provide this. The Editor in Chief has therefore lost confidence in the integrity of the data and results of this article.None of the authors responded to any correspondence from the editor about this retraction."}
{"text": "Dear Editor,1 with great interest, thank you for your comments. We read the letter1 a smartphone-based application can be very useful for daily practice. We think that the main problem in these applications is the difficulty related to language. For example, encephalapp stroop test is in English and you can not change the language of the application. We think also grasping a pen is not the same as using a smartphone screen. For some patients, it is very difficult to use a small phone screen. As the authors mentioned in their letter2We appreciate the authors\u2019 comment and we thank them again for their interest in our article.The authors have no conflict of interest to declare."}
{"text": "It should be PLoS ONE 2021, 16, e0259448Flood, M.W.; Grimm, B. EntropyHub: An open-source toolkit for entropic time series analysis. .In the original article , the refWith this correction, the order of references has not been changed. The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editor's attention by a concerned reader that certain of the cell migration and invasion images shown in Fig. 6B, C, E and F were strikingly similar to data that had already appeared in other articles. Owing to the fact that the contentious data in the above article had already been published prior to its submission to"}
{"text": "Article title: Discovery of novel arylamide derivatives containing piperazine moiety as inhibitors of tubulin polymerization with potent liver cancer inhibitory activityAuthors: Xiao-Yi Shi, Huang Jiao, Jia-Kai Zhang, Xin-Yi Tian, Dan-Feng Guo, Jie Gao, Mei-Qi Jia, Jian Song, Sai-Yang Zhang, Xiang-Jing Fu, Hong-Wei TangJournal:Journal of Enzyme Inhibition and Medicinal ChemistryBibliometrics: Volume 38, Number 1,DOI:https://doi.org/10.1080/14756366.2023.2237701Figure 5A\u2009\u223c\u2009C of this article. The authors would like to apologize for any inconvenience caused. The correct version of Figure 5 is as follows:The authors regret the following errors in"}
{"text": "RSC Advances article due to concerns with the reliability of the data.The Royal Society of Chemistry, with the agreement of the authors, hereby wholly retracts this Concerns were initially raised with the integrity of the western blots in Fig. 6.The authors provided raw data for the western blot images which does not appear to be genuine. The raw data shows signs of cloning as duplicating features can be observed, which indicates that the images have been manipulated.The authors state that they outsourced the western blot experiments in this paper and have offered to re-perform this work. However, given the significance of the concerns about the validity of both the data in the article and the raw data provided by the authors, the findings presented in this paper are not reliable.Signed: Zehai Song, Hang Chang, Na Han, Zhihui Liu, Ye Liu, Hui Wang, Jingxuan Shao, Zhonglin Wang, Hao Gao and Jun YinDate: 24th March 2023"}
{"text": "Oncol Rep 29: 151\u2013159, 2012.Oncology Reports, the Editor has decided that this paper should be retracted from the Journal. After having been in contact with the authors, they accepted the decision to retract the paper. The Editor apologizes to the readership for any inconvenience caused.Owing to the fact that the contentious data in the above article had already been published prior to its submission to"}
{"text": "Mammaliicoccus sciuri DNA instead of Trueperella pyogenes. The conclusions reported in the article are no longer supported by the analyses; therefore, the article has been retracted.Following publication, the authors contacted the Editorial Office to request the retraction of the cited article, stating that further analysis of phage vB-ApyS-JF1 sequencing data discovered contamination with This retraction was approved by the Chief Editors of Frontiers of Microbiology and the Chief Executive Editor of Frontiers. The authors agree to this retraction."}
{"text": "Retraction Note : Journal of Orthopaedic Surgery and Research (2022) 17:528 https://doi.org/10.1186/s13018-022-03410-zThe Editor-in-Chief has retracted this article. Following publication, concerns were raised that the study reported in this article included data from patients who had undergone tibial transverse transport (TTT) as early as 2015. The authors were asked to provide example scans from 2015 from their dataset. However, the scans provided did not depict the required areas and the procedures discussed in the article. The Editor-in-Chief therefore no longer has confidence in the results and conclusions presented. None of the authors has responded to correspondence from the Publisher about this retraction."}
{"text": "RSC Advances is publishing this Expression of Concern in order to alert our readers to the fact that we are presently unable to confirm the accuracy of the information published in this article related to compound 2w. A reader has raised concerns that the 13C NMR spectrum provided for compound 2w does not fit the reported structure. The authors disagree with the reader's claims. An independent expert has reviewed the matter and has recommended that the authors must provide further evidence, from X-ray or other confirmatory tool, in order to prove the proposed structure of compound 2w.An expression of concern will continue to be associated with this article until a conclusive outcome is reached.Laura FisherRSC AdvancesExecutive Editor, 4th October 2023."}
{"text": "Subsequently, the Editorial Office conducted an independent investigation of this paper, and it was found that cellular data featured in both Figs. 3E and 4B in the above paper had already been published in the following respective articles, written by different authors at different research institutes: Sheu J-J, Lee F-Y, Wallace GC, Tsai T-H, Leu S, Chen Y-L, Chai H-T, Lu H-I, Sun C-K and Yip H-K: Administered circulating microparticles derived from lung cancer patients markedly improved angiogenesis, blood flow and ischemic recovery in rat critical limb ischemia. J Transl Med 13: 59, 2015; and Zhang M, Wang L, Dong M, Li Z and Jin F: Endothelial semaphorin 7A promotes inflammation in seawater aspiration-induced acute lung injury. Int J Mol Sci 15: 19650-19661, 2014].Experimental and Therapeutic Medicine, the Editor has decided that this paper should be retracted from the Journal. The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Owing to the fact that the contentious data in the above article had already been published prior to its submission to"}
{"text": "Retraction Note: BMC Complement Med Ther 20, 120 (2020)10.1186/s12906-020-02902-xThe Editor has retracted this article at the request of the corresponding author because the authors have been unable to repeat the results. In addition, there appears to be significant overlap with another publication . Wen Hua"}
{"text": "After having been in contact with the authors, they accepted the decision to retract the paper. The Editor apologizes to the readership for any inconvenience caused.In view of the fact that certain of the data in the above article had already appeared in a previously published paper, and given the large number of apparently overlapping data panels identified in several of the figures, the Editor of"}
{"text": "With this notice, Transplant International states its awareness of concerns as raised by the authors regarding the data validity of \u201cReal-World Treatment Patterns of Antiviral Prophylaxis for Cytomegalovirus Among Adult Kidney Transplant Recipients: A Linked USRDS-Medicare Database Study\u201d published on 12 August 2022. While a revised version is currently being conducted by the authors in collaboration with the Editorial Office, this expression of concern has been posted while Transplant International awaits the revisions. It will be updated accordingly after that time."}
{"text": "Diabetol Metab Syndr (2019) 11:5Retraction: Khalili 10.1186/s13098-019-0400-7The Editor in Chief has retracted this article because it has been previously published by some of the same authors . This ar"}
{"text": "The revised version of"}
{"text": "To the Editor:We would like to thank Professor Marshall Lichtman for his letter, his interesting proposal, and using this venue to promote discussion of the topic. Professor Lichtman proposed a numerical calculation for authorship based on the authors\u2019 perceptions of their relative contribution to a scientific publication,However, we question whether this proposal will solve authorship problems in academic publishing. Take, for example, coercive authorship. If Lichtman\u2019s proposal is adopted, certain individuals\u2019 demands might not be satisfied by being given a place in the authors\u2019 byline. These individuals would now demand a substantial \u201cshare\u201d within the fractional contribution to legitimize their inclusion. In such a case, the relative \u201ccontribution\u201d of legitimate authors can only decrease. Such a scenario could potentially transform legitimate contributors into ghost authors, further exacerbating the problem of misattributed authorship.Contrary to Lichtman\u2019s model, in which the only parameter examined is the authors\u2019 roles in deciding who contributed and the degree to which they contributed, our study evaluated the impact of the institutions with which the authors were affiliated on authorship misconduct. We evaluated authorship dispute since it is a commonly encountered situation. We maintain that the issues underlying these disputes are much larger than just a personal disagreement between individual contributors. Typically, although several parties may be involved in a dispute (disputing authors and their institution(s)), only the disputing authors are officially engaged in the conflict; the institutions become officially involved only if it is reported to them. Lichtman\u2019s model, however, assumes that the institutions of disputing authors have no influence on the evolution of the conflict. The results of our study question Lichtman\u2019s assumption. We showed that increasing experience with authorship misconduct is associated with lower Trust Scores in the respondents\u2019 institutions. In fact, most respondents preferred not to involve their administration in resolving a conflict if there was an authorship dispute. These respondents did not perceive their institutions to be passive or neutral third parties.An idealistic view of academia leads to shock at the thought that a scientist, who has spent years studying, exploring, and teaching, would be willing to engage in misconduct such as placing one\u2019s name on a scientific publication without justification or, worse, falsifying and fabricating experimental results. The incentive is the pressure to publish at any cost. This pressure is not inborn. Rather, this pressure is the consequence of institutional demands.Many organizations, such as the US Office of Research Integrity, argue that authorship complaints should be tagged as authorship disputes rather than acts of misconduct such as plagiarism.discredit and constitutes plagiarism.Take, for example, author displacement. According to The European Code of Conduct for Research Integrity, \u201cPlagiarism is using other people\u2019s work or ideas without giving proper credit to the original source.\u201dBoth plagiarism and other causes commonly underlying authorship disputes belong within the spectrum of inappropriate crediting of an individual\u2019s contributions to the scientific record . Ghost aWe believe that the scientific establishment must stop diminishing the significance of authorship disputes. The root causes of such disputes and the system failures to resolve them should be sought and addressed. If underlying misconduct is encountered, institutions must not ignore it, regardless of the seniority or tenure of the faculty member involved. We wish to quote one of our survey respondents who commented on the importance of the active role of institutions: \u201cWithin our institute, we have clear rules and guidance on how authorship is handled, and we rarely have issues with authorship. Therefore, in our environment, authors can handle this [dispute] themselves.\u201d Our study clearly showed that Trust was higher and that gift authorship rates were lower in institutions that made known their authorship policies.Institutions should actively foster a culture embracing research and publication integrity. To that end, institutions should seek to be more proactive in the prevention and resolution of authorship disputes. Integral steps include establishing and publishing a non-ambiguous policy, examination of the source of such disputes, and setting in motion processes that will promote equitable authorship dispute resolution.We would like to thank Professor Lichtman for raising the issue of proper attribution of authorship, which is the basis for avoiding authorship disputes."}
{"text": "MMWR Editors were informed by authors of \u201cTiming of Introduction of Complementary Foods \u2014 United States, 2016\u20132018\u201d (On May 25,"}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Owing to the fact that some of the data in the above article had already been published, or were under consideration for publication, prior to its submission to"}
{"text": "Scientific Reports 10.1038/s41598-022-11642-6, published online 07 May 2022Retraction of: Editors have retracted this Article.1. The Editors requested the Authors to provide raw original data and explanations regarding the contributions and the overlap but found the response provided by the Authors insufficient. Given these issues and that authorship of the paper could not be verified, the Editors no longer have confidence in the content of this Article.After publication, concerns were raised about authorship and description of author contributions, as well as nonsensical phrases used in the Article and an overlap with a previously-published paper that shares 3 authors in commonShaghaiegh Baghaie disagrees with this retraction. Qun Liu did not respond to the correspondence about this retraction. The Editors have not been able to establish current email addresses for Olga Bykanova, Ravil Akhmadeev, Maboud Hekmatifar, Ahmadreza Arefpour, Roozbeh Sabetvand & Vitaliy Borisov."}
{"text": "This article has been corrected at the request of the submitting author to change affiliation information.For each of the four authors, their affiliation information has been changed from \"Saint James School of Medicine, Chicago, USA\" to \"Saint James School of Medicine, Arnos Vale, VCT\".The authors deeply regret that this error was not identified and addressed prior to publication."}
{"text": "In \u201cPreliminary Investigation of Shift, a Novel Smartphone App to Support Junior Doctors\u2019 Mental Health and Well-being: Examination of Symptom Progression, Usability, and Acceptability After 1 Month of Use\u201d :e38497) the authors noted one syntax error:A total of 222 female  junior doctors provided full baseline data.The corrected version is:A total of 222  junior doctors provided full baseline data.\u201dThe correction will appear in the online version of the paper on the JMIR Publications website, together with the publication of this correction notice on April 3, 2023. Because this was made after submission to PubMed, PubMed Central, and other full-text repositories, the corrected article has also been resubmitted to those repositories."}
{"text": "Cancer Gene Therapy 10.1038/s41417-022-00582-y, published online 04 January 2023Correction to: In the article \u201cSingle-cell RNA sequencing reveals changes in glioma-associated macrophage polarization and cellular states of malignant gliomas with high AQP4 expression\u201d by Wang et al., Cancer Gene Ther., 2023, 10.1038/s41417-022-00582-y, a correction was needed.The order of the author list should be \u201cRan Wang, Lu Peng, Yong Xiao, Qi Zhou, Zhen Wang, Lei Tang, Hong Xiao, Kun Yang, Hongyi Liu, Li Li\u201d.The order of the corresponding authors\u2019 email addresses should be \u201cemail: doctoryk@njmu.edu.cn; njnkyylhy@163.com; annylish@126.com\u201d.The claim of the corresponding authors should be \u201cCorrespondence to Kun Yang, Hongyi Liu or Li Li.\u201d in the HTML version, and \u201cCorrespondence and requests for materials should be addressed to Kun Yang, Hongyi Liu or Li Li.\u201d in the PDF version.The original article has been corrected."}
{"text": "This is a peer-review report submitted for the paper \u201cWhy We Are Losing the War Against COVID-19 on the Data Front and How to Reverse the Situation\u201d.This paper  is inter1. The authors should ensure that their points are supported by citations, appropriate to a scientific manuscript.who would regulate the sharing of the data across systems and international borders , who would coordinate the analyses conducted with shared data to make sure that there is efficiency  and that appropriate analyses are conducted, and where would the funding coming from .2. The authors should address several main barriers to the recommendations made\u20143. Not all authors use preprints, and peer review has not been effective in addressing some rushed science, particularly in the last few months. How should these concerns be addressed?The authors have been responsive to the reviewers\u2019 comments and have improved the piece. I have a few remaining concerns, as noted below.1. The paper could still benefit from references to support the authors\u2019 points. For example, the first paragraph does not include a single reference. As another example, point 7\u2014what evidence do the authors have that, \u201cthe more relevant the data of the registry and the larger the potential research community, the bigger the bottleneck is likely to be\u201d?2. Epidemiological data are, in fact, telling us who is more likely to be infected\u2014by race, ethnicity, age, etc. The authors should clarify the unique contribution of clinical data.3. It is not clear what the authors mean by \u201cIn large health systems that cover most of the population cases can be captured rather quickly if the learning system is implemented and coordinated across sites (hence the need for regulating and standardising the methods).\u201d4. The authors do not clearly define the health learning system in contrast to current practices."}
{"text": "After having been in contact with the authors, they agreed with the decision to retract the paper. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors\u2019 attention by a concerned reader that certain of the data shown for the Transwell cell migration and invasion assays in Figs. 2C, 5D and 6D were strikingly similar to data appearing in different form in other articles by different authors, several of which have been retracted. Owing to the fact that the contentious data in the above article had already been published elsewhere, or were already under consideration for publication, prior to its submission to"}
{"text": "The authors would like to make corrections to the reference citations in the original article . The autThe authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "In our original paper, there are two errors:(1)(2)The corrections to the figures do not affect in anyway the conclusion,discussion, or data interpretation of the work since the misplacementof the images was due to an editorial error. No other errors are presentin the published paper."}
{"text": "In \"Assessment of the Efficacy, Safety, and Effectiveness of Weight Control and Obesity Management Mobile Health Interventions: Systematic Review\" :e16899) the authors noted one clarification that should be added:The Acknowledgments section reads as:All authors contributed equally. The research for this paper was fully funded by the Instituto de Salud Carlos III from the Spanish Ministry of Science, Innovation and Universities, grant number PI16/01764.And will be changed to:All authors contributed equally. The research for this paper was fully funded by the Instituto de Salud Carlos III from the Spanish Ministry of Science, Innovation and Universities, grant number PI16/01764 co-funded by FEDER.The correction will appear in the online version of the paper on the JMIR Publications website on April 10, 2023 together with the publication of this correction notice. Because this was made after submission to PubMed, PubMed Central, and other full-text repositories, the corrected article has also been resubmitted to those repositories."}
{"text": "Chitinase 1 (CHIT1) plays a role in the pathogenesis of pulmonary fibrosis by modulating canonical and noncanonical TGF-\u03b2 signaling via interaction with TGFBRAP1 and FOXO3. These findings highlight the CHIT1/SMAD7 axis as a potential biomarker and therapeutic target of pulmonary fibrosis. PMID: 31085559.Article: Lee C-M, He C-H, Park JW, Lee JH, Kamle S, Ma B, Akosman B, Cotez R, Chen E, Zhou Y, Herzog EL, Ryu C, Peng X, Rosas IO, Poli S, Bostwick CF, Choi AM, Elias JA, Lee CG (2019 May 13) Chitinase 1 regulates pulmonary fibrosis by modulating TGF-\u03b2/SMAD7 pathway via TGFBRAP1 and FOXO3. Life Sci Alliance 2(3): e201900350. doi: The authors identified that there were two inadvertent mistakes that led to the duplication of some of the blots that made up the panels in Editor\u2019s note: The authors requested the publication of a corrigendum promptly when the error was first noted and the delay in publishing the corrigendum was not due to any fault or delay on the part of the authors of the article."}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, a concerned reader drew to the attention of the Editorial Office that, for the flow cytometric plots shown in Fig. 4A on p. 1012, in comparing the dats shown for the T98G and U87MG experiments, the plots in the lower pair of quadrants looked remarkably similar, whereas the data in the upper pair of quadrants were clearly different. Upon assessing the matter raised by the reader, the Editor of"}
{"text": "A recent paper in this journal by Mozaffari et al.  reportedThe authors correctly argue that LCSA is an integrated approach to cover the three aspects of sustainability: environmental, economic and social  at a location (Bardaskan). That is valuable. But an activity is not a life cycle (Heijungs & Cucurachi,"}
{"text": "Finally, there were erroneous calculations included for the CtBP1 expression data shown in Table III.Oncology Reports has decided that this paper should be retracted from the Journal due to an overall lack of confidence in the presented data. After contacting the authors, they accepted the decision to retract this paper. The Editor apologizes to the readership for any inconvenience caused.Given the large number of apparent errors that were made during the assembly of various of the figures and Table III in this paper, the Editor of"}
{"text": "The authors have previously requested to correct Figure 6A, and this request was under consideration at the time these additional concerns were raised by readers.The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an expression of concern to notify readers whilst the Editorial Office investigates. It has been noted that the Western blots of Figure 5C appear similar to those in a retracted publication by a different author group (DOI:"}
{"text": "In the original publication , there wThere was an error in the original publication. The dosage of hypoxanthine (Hypox) was incorrectly stated in the original publication. The dosage of Hypox should be 500 mg/kg.Section 3. Discussion, Paragraph 8:A correction has been made to \u201cIn this study, Allop was demonstrated to decrease the levels of liver XOD and serum UA, and increase the levels of urine CRE (day 6) in this rapid HUA mouse model. However, Allop did not reverse the increased serum levels of CRE and BUN in HUA mice. By contrast, Chen et al. [64] reported that Allop was able to decrease serum levels of CRE and BUN in HUA mice. The underlying cause to explain the conflicting findings may be attributed to the differences in the approaches to establish HUA mouse model. In their study, the authors employed intraperitoneal injection with PO to establish the HUA mouse model. However, in the present study, Hypox  was used to induce HUA mice in addition to PO exposure.\u201dThe authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Owing to the fact that the contentious data in the above article were already under consideration for publication, or had already been published elsewhere, prior to its submission to"}
{"text": "Nature Communications 10.1038/s41467-017-01224-w, published online 27 October 2017Retraction to: The authors are retracting this Article after they became aware that Fig. 2g, 3a, 3d, 4b-d, 5a, 5d, and Supplementary Fig. 1a were prepared in an inappropriate manner.The blot images shown in Fig. 2g, 3a, 3d, 4b, 5a and 5d assess TOR activity and autophagy, and were produced by assembling different sections of the original blot images in a way that did not indicate the splicing and merging of lanes, and in some cases the loading controls shown did not correspond to the correct gels/blots. In addition, background sections of the plant images shown in Fig. 4c-d had been duplicated. Finally, the gel images shown in Supplementary Fig. 1a to confirm plant genotypes contain internal duplications and the original data cannot be found. Subsequent genotyping data has confirmed the genotype of the plants and the authors continue to believe that the data on TOR activity and autophagy are supported. The authors maintain full confidence in the metabolic profiling and transcriptomic data in the paper. Nevertheless, they recognize that the irregularities in image presentation could collectively decrease confidence in the conclusions.The authors apologise to the scientific community for any confusion caused by these errors. All authors agree to this retraction."}
{"text": "STXBP1-Related Disorder Patient Neurons,\u201d by van Berkel et\u00a0al. .Erratum to: \u201cReduced MUNC18-1 Levels, Synaptic Proteome Changes, and Altered Network Activity in STXBP1 mutation pathogenic for this patient is c.704G>A, p.Arg235Gln, and not c.[922A>T], p.[Lys308(\u2217)]. According to the authors, the reporting mistake in the previous article was caused by a mix-up between the mutations of two different patients affected by the same condition.A correction for this article has become necessary, as the mutation originally reported as K308X for patient 5 should instead be R235Q. Specifically, authors of a previous study, on which this study was partially built, recently found that the All references to this mutation have now been corrected to R235Q."}
{"text": "Retraction Note : Cellular & Molecular Biology Letters (2019) 24:13 10.1186/s11658-019-0137-1The Editor in Chief has retracted this article because of concerns about the data presented. Specifically, the flow cytometry plots presented in Fig.\u00a01E show a significant similarity to the plots presented in a previously published paper with no common authors . The Edi"}
{"text": "Authors declare no conflict of interests for this article.I read with great interest the paper by Sinha et al. about Takotsubo syndrome (TS) in subjects undergoing catheter ablation for atrial fibrillation (AF) based on multicenter retrospective database.I have two comments and questions for the author: (1) Have you taken into consideration coronary spastic angina (CSA)? It is well known that CSA can be caused by direct thermal damage resulting from radiofrequency (RF) energy or an autonomic nervous system imbalance."}
{"text": "Following publication, concerns were raised regarding the integrity of the images in the published figures. The authors failed to provide a satisfactory explanation during the investigation, which was conducted in accordance with Frontiers' policies. As a result, the data and conclusions of the article have been deemed unreliable and the article has been retracted.The retraction was approved by the Chief Editors of Frontiers in Cellular Neuroscience and the Chief Executive of Frontiers. The authors did not agree to the retraction."}
{"text": "Scientific Reports 10.1038/s41598-019-44979-6, published online 21 June 2019Retraction of:The Editors have retracted this article.An investigation by Albany College of Pharmacy and Health Sciences has concluded that the content of four images in Fig.\u00a010b appears to have been misrepresented.1 and to PBS image in Fig.\u00a04 of2.The PBS control appears identical to b-FGF\u2009+\u20097 in Fig.\u00a043.The b-FGF image appears identical to VEGF in \u2018corrected\u2019 Fig.\u00a02A of1 and to b-FGF\u2009+\u2009Au-glucose in Fig.\u00a04 of2.The b-FGF\u2009+\u2009DAT image appears identical to b-FGF\u2009+\u20095 in Fig.\u00a04 of1 and to b-FGF\u2009+\u2009Ag-DAPHP in Fig.\u00a04 of2.The b-FGF\u2009+\u2009N-DAT image appears identical to b-FGF\u2009+\u2009tetrac in Fig.\u00a04 ofSpecifically:The Editors therefore no longer have confidence in the results and conclusions presented.Murat Yalcin, Qishan Lin, Kavitha Godugu, Kazutoshi Fujioka, Kelly A. Keating & Shaker A. Mousa did not respond to the correspondence from the Editors about this retraction. The Editors were not able to confirm the current contact details for Weikun Li and Dhruba J. Bharali."}
{"text": "Dhana A, Hamada Y, Kengne AP, et al. Tuberculosis screening among ambulatory people living with HIV: a systematic review and individual participant data meta-analysis. Lancet Infect Dis 22: 507\u2013182022; \u2014In the Acknowledgments section of this Article, the authors have added the statement: \u201cWe acknowledge the provision of data by the AIDS Clinical Trials Group\u201d. This correction has been made to the online version as of April 17, 2023."}
{"text": "Correction to: Stem Cell Research & Therapy 10.1186/s13287-021-02678-yIn the original article, the authors identified two editing errors: Methods section, concretely in the Study population subsection, a typing error was made, since it states that twenty-seven women were included in the study (14 with GDM and 14 with NGT), but indeed there are twenty-eight women.1. In the 2. In Table"}
{"text": "Correction: Molecular Medicine (2023) 29:49https://doi.org/10.1186/s10020-023-00638-1Following publication of the original article  Representative Micro-CT images of 3-month-old caRhoA and RCre;caRhoA mice tibias. (b) The parameters of tibias growth plate trabecular bone, n\u2009=\u20096. (c) Representative H&E and TRAP staining images of mice femurs. Scale bars, 200\u00a0\u00b5m (H&E) and 20\u00a0\u00b5m (TRAP). (d) The parameters of femur osteoclasts, n\u2009=\u20096. (e) Representative TRAP staining images of BMMs from caRhoA and RCre;caRhoA mice. Scale bars, 200\u00a0\u00b5m. (f) SEM analysis and quantification of bone resorption area of bone slides, n\u2009=\u20096, Scale bars, 20\u00a0\u00b5m. (g) Representative Phalloidin staining images and quantification of F-actin ring per well and nuclei per osteoclast, n\u2009=\u20093, Scale bars, 500\u00a0\u00b5m. Mean\u2009\u00b1\u2009s.d., *P\u2009<\u20090.05, Student\u2019s t-test.Additional file 1: Figure S4. The authors confirm all results, and conclusions of this article remain unchanged. The authors apologize for this error and any confusion it may have caused."}
{"text": "The authors regret that they divided the blots from the same groups of samples into two images  in consideration of layout neatness but used the same \u03b2-actin. Although Fig. 4 C and D were both from the same group of samples, it is not properly to use the same \u03b2-actin in Fig. 4 C and 4D. Similar blot division and usage of the same \u03b2-actin could also be found in Fig 5B and 5C. The authors would like to merge figure Fig. 4C and D into one image, and merge figure Fig.5B and 5C into one image. Thus, they make this corrigendum."}
{"text": "Ward et al., Chem. Sci., 2023, 14, 2024\u20132032, https://doi.org/10.1039/D2SC06375A.Correction for \u2018Isolation of C1 through C4 derivatives from CO using heteroleptic uranium( The correct C\u2013O bond distance in complex 3 is 1.158(6) \u00c5, while the one quoted in the manuscript of 1.363(4) \u00c5 is the C\u2013O distance in the U\u2013O\u2013C(ipso).The authors regret that the C\u2013O bond distance for complex The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "In the original publication , the autFigure 1. Concept of an overlapping spectrum of allergic fungal airway diseases. Adapted from reference [7]. \u2018Journal of Asthma and Allergy 2021:14 557\u2013573\u2019, originally published by and used with permission from Dove Medical Press Ltd.\u201d\u201cThe original publication has also been updated."}
{"text": "The authors regret that the Author contributions statement was shown incorrectly in the original manuscript. The corrected Author contributions statement is shown here.Xingyu Liu and Lili Xu contributed equally to this work. Xingyu Liu: conceptualization, investigation, methodology, writing \u2013 original draft. Lili Xu: methodology, validation, conceptualization, theoretical analysis. Shuaisheng Zhao: investigation, validation, methodology, writing \u2013 review & editing. Haoxuan Hua: investigation. Gang Li: investigation. Jinlei Wang: investigation. Yifan Su: investigation. Xinquan Yu: funding acquisition, review & editing. Youfa Zhang: project administration, supervision, review & editing.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "This erratum corrects the following:J Appl Clin Med Phys. 2022; 22: 175\u2013181. https://doi.org/10.1002/acm2.13234Ferris WS, Culberson WS, Smilowitz JB, Bayouth JE. Effects of variable\u2010width jaw motion on beam characteristics for Radixact Synchrony\u00ae. John E. Bayouth reports ownership interest in a company that provides consulting services on image\u2010guided radiation therapy technology . He/(his employer) received travel reimbursement/speaking fees from ViewRay Inc. The remaining authors have no conflicts of interest to disclose."}
{"text": "The journal retracts the 2022 article cited above.Following publication, concerns were raised regarding the contributions of the authors of the article. Our investigation, conducted in accordance with Frontiers policies, confirmed a serious breach of our authorship policies and of publication ethics; the article is therefore retracted.This retraction was approved by the Chief Editors of Frontiers in Psychology and the Chief Executive Editor of Frontiers. The authors responded to the concerns raised, but did not provide a satisfactory explanation. The authors do not agree to this retraction."}
{"text": "In the original publication , there wAuthor Contributions: Conceptualization, K.D. and T.L.; investigation, K.D. (reviewed 78 articles), K.E. (reviewed 7 articles) and T.L.; methodology, K.D.; visualization, K.D.; supervision, T.L.; writing\u2014original draft, K.D.  and K.E. (Sections 4.2.2 and 5); writing\u2014review and editing, K.D., K.E., T.L. and C.L. All authors have read and agreed to the published version of the manuscript.Khang Dang was not included as an author in the original publication. The corrected Author Contributions statement appears here.The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "Nature Communications 10.1038/s41467-019-09865-9, published online 06 May 2019Retraction to: The authors have retracted this article due to image errors across the figures, and some of the data lacking biological repeats, which calls into question the reliability of the data and the conclusions. In particular, there are errors in the immunohistochemistry images in Figure 6A, invasion assay images in Figure 1C, western blots  and would healing assay images . The authors would like to apologize for any inconvenience caused to the community.Xinyao Lin, Guoshi Chai, Yingming Wu, Jiexin Li, Feng Chen, Jianzhao Liu, Guanzheng Luo, Jordi Tauler, Shuibin Lin, Chuan He and Hongsheng Wang agree to this retraction. Jun Du has not responded to any correspondence from the editor or publisher about this retraction."}
{"text": "CorrectionThe original articles , 2 mista"}
{"text": "In the original publication , there wThe authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Owing to the fact that the contentious data in the above article had already been submitted for publication elsewhere prior to its submission to"}
{"text": "Biomarker Research (2023) 11:9710.1186/s40364-023-00536-yThe original article [1] contained an error in the affiliations of co-authors, Yaqi Zhang and Xuefeng B. Ling due to a no-fault misinterpretation during the proofing process. The affiliations have since been amended to reflect the affiliations that were originally requested by the authors."}
{"text": "Retraction Note: J Ovarian Res 6, 52 (2013)https://doi.org/10.1186/1757-2215-6-52The authors have retracted this article. After 10\u00a0years of publication, a concern was raised regarding highly similar cell pattern in different area of Fig.\u00a02A. The corresponding author has stated that Fig.\u00a02A is a composite image, and unintentional duplication occurred while compiling the data. The corresponding author has also stated that bright field smear images in Figs. 1\u20133 are composite, due to a low number of cells spread apart across the sample, which should have been indicated in the figure legends. The authors are preparing a revised version of this manuscript for peer review.Hiren Patel, Deepa Bhartiya, Seema Parte and Mithun Bhatt agree to this retraction. The Publisher has not been able to obtain current email addresses for Pranesh Gunjal and Snehal Yedurkar."}
{"text": "The Acknowledgements section is missing in the paper. The correct Acknowledgements is as follows: The authors would like to acknowledge the support of Prince Sultan University for paying the Article Processing Charges (APC) of this publication."}
{"text": "There was no probiotics supplementation in the study, so the erratum would be necessary. The correction is as follows:In the original publication , there wFigure 5. Effect of the eight-week training intervention on NH3 (A), LDH (B), and CK (C) levels after an acute exercise challenge (20 min treadmill). Blood was immediately sampled after the exercise for biochemical assessments. Data are represented as mean \u00b1 standard deviation, and the columns with different letters  indicate significant difference at p < 0.05.\u201d\u201cThe authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "The correct version of funding information can be found below:In the original published version of this article, the authors have not provided the complete funding information. The funding information has now been updated. 10.13039/501100012650TU Wien Bibliothek for financial support through its Open Access Funding Program.The authors acknowledge The authors apologize for the errors. Both the HTML and PDF versions of the article have been updated to correct the errors.The authors declare no conflict of interest."}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Owing to the fact that the contentious data in the above article had already been published elsewhere, or were under consideration for publication, prior to its submission to"}
{"text": "In the original publication , there wIn In The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive any reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editor's attention by a concerned reader that certain of the data shown for the Transwell cell migration and invasion assays in Figs. 2C and 4C were strikingly similar to data appearing in different form in another article by different authors at a different research institution. Owing to the fact that the contentious data in the above article were under consideration for publication elsewhere at a similar time to when it was submitted to"}
{"text": "In Methods section \u201cTranscutaneous immunizations\u201d DI-TCI was replaced by DIVA, and finally typos were fixed in Figs 3 and 6. Those changes have now been updated in the HTML and PDF version of this Article.Figs. 3 and 6 are attached."}
{"text": "Moreover, three overlapping data panels were identified in Fig. 6A, such that data which were intended to show the results from differently performed experiments appeared to have been derived from the same original source(s). In view of the fact that certain of these data had already apparently been published previously, and given the lack of rigour on the part of the authors in assembling the figures, the Editor of Experimental and Therapeutic Medicine has decided that this paper should be retracted from the Journal. After having been in contact with the authors, they agreed with the decision to retract the paper. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors\u2019 attention by a concerned reader that the Transwell invasion assay data shown in Fig. 6B on p. 3085 were strikingly similar to data appearing in different form in other articles written by different authors at different research institutes that had either already been published elsewhere prior to the submission of this paper to"}
{"text": "Scientific Reports, 10.1038/s41598-022-10958-7, published online 02 May 2022Retraction of: The Authors have retracted this Article.Following the publication of the Article, the authors have identified a number of errors which invalidate the results reports in this paper. First, in \u201cCase studies\u201d, subheading \u201cBasic data\u201d, for the simulation the output data shown in Figure 2 were used as input. Since these are not real data, the results of the simulation are incorrect. Second, in \u201cMethods: solving an integrated demand response IES optimization dispatch model for electricity and heat\u201d, in the description of the application of the IGWO to the IES scheduling optimisation, in Step 4 the Authors incorrectly used the FCM clustering algorithm, which is not an appropriate solution. This makes the whole process incorrect. Finally, in \u201cIntegrated demand response model for electric and thermal multiple loads\u201d the Authors did not consider the real-time capacity variation which makes the mathematical model incorrect.All Authors agree with the retraction and its wording."}
{"text": "Scientific Reportshttps://doi.org/10.1038/s41598-022-13692-2, published online 08 June 2022Retraction of: The Editors have retracted this Article.After publication, concerns were raised the validity of the XRD spectra presented in Figure\u00a01, and the authorship and author contributions. The Editors requested the authors to provide raw original data and explanations regarding the contributions, but found the response provided by the Authors insufficient. The Authors were also not able to provide all of the original data with meta-data that would allow for the verification of its veracity. Additionally, references 18\u201368 appear to be unrelated to the research described in this Article. The Editors therefore no longer have confidence in the reliability of the data presented in this Article.Merhdad Khatami does not agree to this retraction. Maryam Darvish, Navid Nasrabadi, Farnoush Fotovat, Setareh Khosravi, Samira Jamali, Elnaz Mousavi, Siavash Iravani and Abbas Rahdar have not responded to any correspondence from the Editor about this retraction."}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editor's attention by a concerned reader that the colony formation data shown in Fig. 2C on p. 333 had already appeared in previously published articles written by different authors at different research institutes. Owing to the fact that the contentious data in the above article had already been published prior to its submission to"}
{"text": "Retraction Note: BMC Infectious Diseases (2020) 20:94910.1186/s12879-020-05630-2The Editor has retracted this article because the authors have been unable to provide documents confirming that ethics approval was obtained for the study. None of the authors have responded to correspondence from the Editor about this retraction."}
{"text": "Following the publication of this article , concern\u03b2-actin panels in Figs 7D and 7K.\u03b2-actin panels in Figs 8E and 9D.c-fos panels in Figs 9D and 9E.The following panels appear similar despite representing different conditions:Data tables are not consistent with the reported number of samples in multiple graphs.The corresponding author provided original uncropped western blots underlying some of the results in Figs 7\u20139. In relation to the three pairs of similar panels representing different conditions in Figs 7D and 7K, 8E and 9D, and 9D and 9E, the corresponding author stated that the pairs are not the same. Their responses and the original uncropped images did not resolve the concerns regarding similarity between these blots.The corresponding author provided data tables underlying all graphs other than those in Fig 5 and Fig 6D. Data tables underlying the graphs in Figs 3A, 6C, 7, 8 and 9 contain less samples than indicated in the corresponding figure legends. Data tables underlying the graphs in Fig 4 contain inconsistent numbers of samples for the Tempol and FG-7142 groups. Additionally, many data tables contain values labelled as outliers that were excluded from analyses. The corresponding author\u2019s responses did not resolve these concerns which question the accuracy of data reporting and the reliability of the results.PLOS ONE Editors retract this article.In light of the concerns affecting multiple figure panels that question the reliability of these data, the SS did not agree with the retraction and stands by the article\u2019s findings. All other authors either did not respond directly or could not be reached."}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of the above paper, it was drawn to the Editors' attention by a concerned reader that western blot data shown in Fig. 2B were strikingly similar to data that had appeared in different form in another article. Owing to the fact that the contentious data in the above article were already under consideration for publication elsewhere prior to its submission to"}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Owing to the fact that the contentious data in the above article had already been published prior to its submission to"}
{"text": "Following the publication of this article , concernIn Fig 1, there appears to be an overlapping region in the A and B panels despite these panels representing CD34 expression in a control group and infants with Sudden Infant Death Syndrome (SIDS) respectively.In Fig 5, there appears to be an overlapping region in the A and B panels despite these panels representing melatonin receptor 1 expression in infants with SIDS and a control group respectively.In Fig 6, there appears to be an overlapping region in the B and D panels despite these panels representing melatonin receptor 1 and melatonin receptor 2 expression respectively.Whilst the underlying data for these panels is provided via a repository of the figures and datasets presented in the published article, the above concerns are additionally present in the underlying data and therefore they do not resolve the concerns. The authors did not provide a response to concerns raised about Figs 1, 5, and 6.PLOS ONE Editors retract this article.In light of the concerns affecting multiple figure panels that question the integrity and reliability of these data, the All authors either did not respond directly or could not be reached."}
{"text": "Retraction: \u2018Comparative molecular docking and molecular\u2010dynamic simulation of wild\u2010type\u2010 and mutant carboxylesterase with BTA\u2010hydrolase for enhanced binding to plastic\u2019, by Fatana Lameh, Abdul Qadeer Baseer, and Abubakar Garba Ashiru, Eng Life Sci. 2021; 13\u201029: The above article, published online on 15 November 2021 in Wiley Online Library (https://doi.org/10.1002/elsc.202100083), has been retracted by agreement between the authors, the journal's Editors in Chief, Prof. Dr. Ralf Takors and Prof. Dr. An\u2010Ping Zeng, and Wiley\u2010VCH GmbH.The retraction has been agreed because the copyright owner, Universiti Teknologi Malaysia, does not consent to publication of the research. Retraction: \u2018Comparative molecular docking and molecular\u2010dynamic simulation of wild\u2010type\u2010 and mutant carboxylesterase with BTA\u2010hydrolase for enhanced binding to plastic\u2019, by Fatana Lameh, Abdul Qadeer Baseer, and Abubakar Garba Ashiru, Eng Life Sci. 2021; 13\u201029: The above article, published online on 15 November 2021 in Wiley Online Library (https://doi.org/10.1002/elsc.202100083), has been retracted by agreement between the authors, the journal's Editors in Chief, Prof. Dr. Ralf Takors and Prof. Dr. An\u2010Ping Zeng, and Wiley\u2010VCH GmbH.The retraction has been agreed because the copyright owner, Universiti Teknologi Malaysia, does not consent to publication of the research."}
{"text": "The correct version of the institutional information of the authors can be found below:In the original published version of this article, the authors have requested to change the institutional information. The institutional information of the authors have been updated. Mohammed I. Abuashour institutional information has been changed from:Renewable Energy Centre, The Hashemite University, Zarqa, 13115, Jordanto:Renewable Energy Centre, Electrical Engineering Department, Faculty of Engineering, The Hashemite University, Zarqa, Jordan.And.Haris M. Khalid L institutional information has been changed from:Department of Electrical and Electronics Engineering, Higher Colleges of Technology, Sharjah 7947, United Arab EmiratesTo.College of Engineering and Information Technology, University of Dubai, Academic City 14143, Dubai, United Arab EmiratesThe authors/publisher apologize for the errors. Both the HTML and PDF versions of the article have been updated to correct the errors.The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper."}
{"text": "In the original publication , there wWith regard to the correction of Table 1, a correction has been made to Section 3.2, Paragraph 1.From raw data of a Eurasian blackbird\u2019s transcriptomic analysis [30] we deduced the mRNA sequences from the positive TDSCs markers CD29, CD44, CD71, CD73, CD90, CD105, and the negative markers CD14, CD34, and CD45. Nucleotide sequence data reported are available in the Third Party Annotation Section of the DDBJ/ENA/GenBank databases under the accession numbers TPA: BK064237-BK064246. From these mRNA sequences, we designed the primers presented in Table 1.The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "Nucleic Acids Research, Volume 28, Issue 4, 15 February 2000, Pages 875\u2013885, https://doi.org/10.1093/nar/28.4.875The Editors were alerted in August 2023 that two areas in the background of Figure 1B appear more similar than expected.The Editors have contacted the authors and are investigating. In the interim, we advise readers to examine the details of this study with particular care.Julian E. Sale, Barry L. StoddardSenior Executive Editors"}
{"text": "Cryptococcus neoformans, FEMS Yeast Research, Volume 20, Issue 3, 11 May 2020, https://doi.org/10.1093/femsyr/foaa015.This is a retraction of Jiu Yi, Junjun Sang, Jingyu Zhao, Lei Gao, Yali Yang, Lei Yan, Chao Zhang, Weihua Pan, Guizhen Wang, Wanqing Liao, Transcription factor Liv4 is required for growth and pathogenesis of https://pubpeer.com/publications/4D828B96E005A6D0D0A2A74312D5B4). That individual asserted they had not been aware of the article, noted inconsistencies with the data presented, did not endorse the research results reported, and stated they had consulted the other named authors, who collectively agreed the article should be retracted. The journal subsequently attempted to contact the other named authors directly, but none of them were responsive. The journal is ultimately retracting this article, because the editor no longer believes the data presented in Figure 2 provides confidence in the construction of the liv4\u0394 mutant, which anchors the study.The last-named author contacted the journal editor in May 2023, after being alerted to concerns with duplicated images in Figure 2, which had been posted on PubPeer in November 2021 ("}
{"text": "We changed this statement to: \u201cThe data of the French HD cohort is available from the corresponding author on reasonable request and institutional data use agreement. For queries to obtain biomaterials, raw and processed data of the CHDI cohort, please contact CHDI Foundation (info@chdifoundation.org)\u201d to the table titles. We updated the title for Table\u00a0S15 to \u201cTable\u00a0S15. CAG and CCG repeat sizes for the French cohort. The repeat sizes were quantified by NanoRepeat from Oxford Nanopore long reads.\u201d We updated Table\u00a0S10 to show that the genomic positions are based on T2T-CHM13v1.1.In the originally published version of this article, we included information from CHDI in Tables\u00a0S11, S14, and S16 inadvertently. This is considered as Material-Related Information by CHDI. We removed the sample-related columns of Tables\u00a0S11, S14, and S16 and added the following sentence \u201cSample-related information can be obtained from the CHDI Foundation \u201d should be \u201c(D),\u201d and \u201c(F)\u201d should be \u201c(E and F).\u201d Additionally, in the main text, the citation of Figure\u00a06I should be Figure\u00a06G.The results and conclusions of the manuscript are not affected by the above changes. The article has been corrected online. The authors regret the errors."}
{"text": "In \u201cVoice-Based Screening for SARS-CoV-2 Exposure in Cardiovascular Clinics (VOICE-COVID-19-II): Protocol for a Randomized Controlled Trial\u201d  the authors noted the following error:In the author list, the first two authors Emily Oulousian and Seok Hoon Chung had contributed equally but this was not listed. In the corrected version the first two authors have been listed as:Emily Oulousian*; Seok Hoon Chung**these authors contributed equallyThe corrections will appear in the online version of the paper on the JMIR Publications website on November 23, 2023, together with the publication of this correction notice. Because this was made after submission to PubMed, PubMed Central, and other full-text repositories, the corrected article has also been resubmitted to those repositories."}
{"text": "Moreover, a range of data included in this paper also appeared in different formats in several other articles published subsequently.Oncology Letters, the Editor has decided that this paper should be retracted from the Journal. After having been in contact with the authors, they accepted the decision to retract the paper. The Editor apologizes to the readership for any inconvenience caused.Owing to the fact that the contentious data in Fig. 5 of the above article were already under consideration for publication prior to its submission to"}
{"text": "The recent review by Dy\u0144ka et al.  conclude(I) The authors call into question the link between elevated low-density lipoprotein cholesterol (LDL-C) and CVD, as they state that association is not causation. However, the AHA presidential panel ranked the link between LDL-C and CVD to reach the level of evidence to meet causality, and this conclusion was reached unanimously by three independent guideline committees based on \u201cLevel A, Strong\u201d evidence . I suspe(II) Despite the authors\u2019 prior dismissal of the link between LDL-C and CVD, they contradictorily proceed to argue that a KGD is favorable in preventing CVD by reducing LDL-C. In any case, the authors cite mostly trials in which diets were designed to be hypocaloric to draw this conclusion. The confounding effects of weight loss were not considered when evaluating the lipid-mediating effects of a KGD. For example, carefully designed metabolic ward studies have revealed that ad libitum intake or weight-maintaining KGDs significantly increases LDL-C and all subfractions ,5. It ha(III) The authors claim that a KGD is more effective in reducing body weight compared to other diets. Ignoring the fact that most of the trials examined were designed to be hypocaloric, it has been demonstrated in a convincing metabolic ward study that calorie-for-calorie, dietary fat restriction reduces fat mass to a greater extent than carbohydrate restriction . In fact(IV) The authors claim that a KGD will favorably impact blood glucose, however, a KGD will also increase fasting free fatty acids (FFAs) ,5. ElevaThe misleading conclusions made by authors will send the wrong public health message, dangerously promoting the use of KGDs in treating CVDs, when, in fact, a KGD likely exacerbates CVD."}
{"text": "A randomized controlled trial of a mindfulness-based intervention program for people with schizophrenia: 6-month follow-up\u201d .The authors clarify that the RCT reported in this Psychological Medicine article was a multi-centre RCT shared part of the data/results of another publication \u201c"}
{"text": "Following the publication of this article , concernIn Fig 2B, the aconitine panel appears similar to the TIF panel found in Fig. 6B of [\u25cb Fig 3C and Fig 3D\u25cb Fig 6C, Fig 6D, and Fig 6E\u25cb Fig 9B and Fig 9CThe following graphs appear similar despite representing different experimental conditions:In Fig 7A, there appear to be vertical discontinuities between lanes 1 and 2 in the Oct4 panel and lanes 1 and 2 in the Nanog panel.In Fig 7A the GAPDH panel appears similar to the beta-actin panel found in Figure 4E of .In Fig 7B, the Notoginsenoside R1 Cleaved Caspase-3 panel appears similar to the Control Pimonidazole panel in Fig. 6A of .In Fig 9A the left region of the Shikonin panel appears to overlap with the right region of the Notoginsenoside R1 panel.In Fig 9A the control, Shikonin, Aconitine Notoginsenoside R1 and combined three compounds panels appear similar to the correspondingly named panels in Fig. 7 of .The authors stated that the underlying data for all figures was no longer available. Regarding the concerns in Fig 2B, Fig 7A and Fig 7B the authors stated they were caused by errors in arranging data in the submission process for  and thatPLOS ONE Editors retract this article.In light of the concerns affecting multiple figure panels that question the integrity and reliability of these data, the All authors either did not respond directly to the editorial decision or could not be reached."}
{"text": "Corentin Warnier, Thibault Gendron, Muhammad Otabashi, Charles Vriamont and Alex Jackson were not included as authors in the original publication . The corAuthor Contributions: A.P.: conceptualisation, investigation, original draft; F.Z.: review, conceptualization; C.W.: methodology, conceptualization; T.G.: methodology, conceptualization; M.O.: methodology, conceptualization, validation; C.V.: methodology, conceptualization; A.J.: funding acquisition, resources, conceptualisation; W.P.F.: funding acquisition, review; K.H.: funding acquisition, review; M.N.: review. All authors have read and agreed to the published version of the manuscript.In the published publication, the following two affiliations are missing:2 Trasis, Rue Gilles Magnee 90, 4430 Ans, Belgium3 Theragnostics Ltd., 1 Sans Walk, London EC1R 0LT, UKIn the original publication, there was a mistake in Funding. The correct version should be:Funding: This research was funded by Theragnostics Ltd.A correction has been made to Conflicts of Interest. The updated text appears below.Conflicts of Interest: Alex Jackson is an employee of Theragnostics Ltd. Charles Vriamont, Corentin Warnier, Thibault Gendron and Muhammad Otabashi are employees of Trasis.The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "First, for the RAHBT cohort, the values for \u201cLumpectomy + radiation\u201d and \u201cLumpectomy \u2212 radiation\u201d were transposed. Second, in the RAHBT \u201cDCIS with invasive recurrence\u201d group, the number of samples with grade 3 DCIS should be n = 3, not 2 as listed. Third, for the RAHBT \u201cDCIS without recurrence\u201d group, there should be n = 53 ER+, not 55 as listed; and n = 15 ER\u2212, not 13 as listed.Table 1 has been corrected in the original article online. The authors apologize for any confusion these errors might have caused. Since these errors only occurred in Table 1, none of the analyses or the conclusions of the paper are affected."}
{"text": "Following publication, concerns were raised regarding the integrity of the images in the published figures. The authors failed to provide a satisfactory explanation during the investigation, which was conducted in accordance with Frontiers\u2019 policies.The authors agree to this retraction.This retraction was approved by the Chief Editors of Frontiers in Pharmacology and the Chief Executive Editor of Frontiers."}
{"text": "Munawar et al., Nanoscale Adv., 2023, https://doi.org/10.1039/d3na00017f.Correction for \u2018Revealing the electronic, optical and photocatalytic properties of PN-M The authors regret that the email address of one of the corresponding authors (Tahani A. Alrebdi) was incorrectly listed as taalrebdi@pnu.edu.pk in the original manuscript. The correct email address  is listed here.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "The journal retracts the 2022 article cited above.Following publication, concerns were raised regarding the contributions of the authors of the article. Our investigation, conducted in accordance with Frontiers policies, confirmed a serious breach of our authorship policies and of publication ethics; the article is therefore retracted.This retraction was approved by the Chief Editors of Frontiers in Chemistry and the Chief Executive Editor of Frontiers. The authors have not responded to correspondence regarding this retraction."}
{"text": "The Editorial Office has been made aware of potential issues surrounding the scientific validity of this paper, hence has issued an Expression of Concern to notify readers.It has been noted by a reader that there is a similarity of the Western blots with those in several other unrelated publications suspected of originating from a third party. The reader has also identified highly similar data between this publication, and that of Zhao et al. 2018 (doi: 10.3892/ijo.2018.4576) and Liang et al. 2017 (doi: 10.3892/or.2017.6049).The authors were contacted regarding the concerns raised and provided the Editorial Office with copies of the original Western blots, however minor differences in the shape and spacing of the bands, as well as the addition/removal of background and surface features can be seen between the original submitted Figures and the raw Western blots images provided post-publication. The authors state that these differences are due to staining due to improper preservation."}
{"text": "Scientific Reportshttps://doi.org/10.1038/s41598-019-45611-3, published online 24 June 2019Retraction of: Editors have retracted this Article.After publication of this paper concerns about ethical oversight of this study were brought to the attention of the Editors. The Authors were not able to provide documentation of appropriate approval from an ethics committee in either Niger or Senegal, where the participants in this study were based.Thi-Phuong-Thao Pham, Cheikh Sokhna, Frank Wieringa, Mathieu Million, and Didier Raoult disagree with this retraction. Maryam Tidjani Alou, Dipankar Bachar, Anthony Levasseur, Souleymane Brah, and Daouda Alhousseini did not respond to correspondence from the Editors about this retraction. The Editors were not able to confirm current contact details for Aldiouma Diallo."}
{"text": "The journal and Chief Editors retract the 20 January 2022 article cited above.Following publication, concerns were raised regarding the quality of the article and the language of the presentation. An investigation was conducted in accordance with Frontiers' policies.A post-publication assessment by an expert in the field found that the complaints were valid and that the study design is not adequate to justify the conclusions drawn by the authors. The article does not meet the standards of editorial and scientific soundness for Frontiers in Computational Neuroscience; therefore, it has been retracted.This retraction was approved by the Chief Editors of Frontiers in Computational Neuroscience and the Chief Executive Editor of Frontiers. The authors did not agree to this retraction."}
{"text": "In the article by Chang et al.,\u00a0, there wThe correct details are as follows:aWing type of male samples is WT\u20103 ). The forewings are shorter than or just reach two\u2010thirds of the hind femur and at least adjoin the back.bWing type of female samples is WT\u20102 ). The wings degenerated into scales, laterally located, usually covering the tympanum, a few do not reach the tympanum.The authors would like to apologise for any inconvenience caused."}
{"text": "Correction to: BMC Surgery 10.1186/s12893-023-02070-y.Following publication of the original article , in thiswww.editage.jp) for English language editing. The authors are grateful to JPSKAKENHI #22K16548.The authors thank Editage ("}
{"text": "Affiliation number 3, \u201cSuizhou No. 2 High School, Suizhou 441300, China\u201d need to be changed to his Current Address. The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated.In the published publication , there w"}
{"text": "Purity, which states that facts about derivative entities are non-fundamental. Purity is questionable. In this paper, I introduce a new argument\u2014the argument from Settledness\u2014for a similar conclusion but which does not rely on Purity. The conclusion of the new argument is that every \u201cthick\u201d grounding fact is grounded, where a grounding fact  is said to be thick when at least one of F, G, H, \u2026 is a fact\u2014a condition that is automatically satisfied if grounding is factive. After introducing the argument, I compare it with the argument from Purity, and I assess its cogency relative to the relevant accounts of the connections between grounding and fundamentality that are available in the literature.Many philosophers have recently been impressed by an argument to the effect that all grounding facts about \u201cderivative entities\u201d\u2014e.g. the facts expressed by the (let us suppose) true sentences \u2018the fact that Beijing is a concrete entity is grounded in the fact that its parts are concrete\u2019 and \u2018the fact that there are cities is grounded in the fact that p\u2019, where \u2018p\u2019 is a suitable sentence couched in the language of particle physics\u2014must themselves be grounded. This argument relies on a principle,  Assume for example the physicalist view that some given microphysical fact grounds the fact that there are cities. What grounds this grounding fact? There is no obvious answer.The argument from Purity poses a serious challenge. For what are the grounding facts about (say) cities grounded in? In some cases, the answer is easy\u2014or so it may seem. Thus, given the orthodox view that grounding is transitive, it is perhaps plausible to hold that.Many philosophers have been impressed by this argument, and several, more or less plausible suggestions about what grounds grounding facts have been put forward in order to accommodate its conclusion.The argument from Purity involves three key notions: a fact\u2019s being about derivative entities, being fundamental, and grounding. Each of these notions is equivocal in the present context, and therefore, before critically examining the argument, one should in principle specify how these notions are to be understood. It can be argued that specifying how the notion of a fact\u2019s being about derivative entities is to be understood is not really mandatory. Instead of critically examining the argument from Purity itself, one may as well critically examine the arguments that result from it by replacing all occurrences of \u2018derivative entities\u2019 by kind terms that pick out entities that presumably count as derivative, e.g. \u2018cities\u2019, \u2018people\u2019, \u2018molecules\u2019 or \u2018planets\u2019. By moving from the \u201cgeneral\u201d argument from Purity to particular \u201cinstances\u201d in the suggested way, something is lost, for sure, but for practical purposes this may not matter.It is common to distinguish between various notions of grounding, e.g. between factive and non-factive, weak and strict, and worldly and representational grounding.weak grounding. Since weak grounding is reflexive, the conclusion of the argument from Purity is trivial, and therefore the argument as a whole is obviously dialectically ineffective. Proponents of the argument are thus best understood as having strict grounding in mind.Suppose for instance that the argument is understood as involving factive notion grounding, i.e. that grounding is understood in such a way that it is impossible that grounding be exemplified without the exemplifiers holding, i.e. without the exemplifiers being facts.Also, suppose that the argument is understood as involving a clearly discarded as being unintended.These considerations leave open the possibility of there being more than one notion of grounding that the argument from Purity can be taken to target. It is also plausible to hold that \u2018fundamental\u2019 may be understood in different ways in the argument. Knowledge of the literature on fundamentality naturally suggests the following four candidate notions: being \u201cnatural\u201d or \u201cjoint-carving\u201d . For consider [NYC\u2009=\u2009NYC]. This is a fact about a city, and hence (presumably) it counts as a fact about derivative entities. By Purity, it is non-fundamental, i.e.  grounded. But is it? [NYC\u2009=\u2009NYC] look very much like a good candidate for being brute, i.e. ungrounded. I do not deny that there are accounts on which this fact is grounded. For instance, friends of grounding who espouse Sider\u2019s conception of fundamentality might suggest that [NYC\u2009=\u2009NYC] is grounded in [def(NYC)\u2009=\u2009def(NYC)], where \u2018def(NYC)\u2019 is a definite description that provides a \u201cmetaphysical definition\u201d of NYC couched in joint-carving terms  Every fact about derivative entities is grounded.Using again [NYC\u2009=\u2009NYC] as I did before, one can argue that Purity* is questionable: granted that [NYC\u2009=\u2009NYC] is a fact about derivative entities, Purity* entails that it is grounded, but the view that it is grounded is questionable. The point is interesting, because it is independent from the particular notion of fundamentality taken to be involved in Purity and NF\u2009\u2192\u2009G.thick grounding fact be a grounding fact [F is grounded in FF] such that F or one of FF holds, i.e. is a fact. If grounding is factive, then all grounding facts are thick, but if grounding is not factive, then there may be\u2014indeed, there certainly are\u2014grounding facts that are not thick. Consider, then, the following argument\u2014the argument from Settledness, as I will call it:1) For every thick grounding fact [F is grounded in FF] and some fact X among F and FF, [F is grounded in FF] is less fundamental than XSettledness2) A fact is non-fundamental if it is less fundamental than another factTruism3) Every thick grounding fact is non-fundamentalBy 1) and 2)4) If a fact is non-fundamental, then it is groundedNF\u2192G5) Every thick grounding fact is groundedBy 3) and 4)Note that by Truism, NF\u2009\u2192\u2009G and the assumption that some fact is less fundamental than some other fact, there are thick grounding facts and hence 5) is not vacuously true. Also note that if grounding is factive, then Settledness is equivalent toFor every grounding fact [F is grounded in FF] and some X among F and FF, [F is grounded in FF] is less fundamental than X,and the conclusion of the argument is equivalent toEvery grounding fact is grounded.Let a not taken to be factive, the conclusion of the argument from Settledness (that every thick grounding fact is grounded) is not logically stronger than the conclusion of the argument from Purity, but it remains at least as challenging as the latter when the focus is on thick grounding facts.The argument from Settledness is in some ways similar to the argument from Purity, and in some ways different. If grounding is taken to be factive, the conclusion of the argument from Settledness (that every grounding fact is grounded) is logically stronger than the conclusion of the argument from Purity (that every grounding fact about derivative entities is grounded). This makes the former argument at least as challenging as the latter.absolute fundamentality , Settledness connects grounding and relative fundamentality . Truism connects absolute and relative fundamentality. Relative fundamentality is completely absent from the argument from Purity .The premises of the two arguments overlap. Like the argument from Purity, the new argument invokes NF\u2009\u2192\u2009G. But unlike the former, it does not invoke Purity\u2014nor any principle involving the notion of a fact\u2019s being about derivative entities, for that matter. It has Settledness and Truism instead. Settledness, like Purity, connects grounding and fundamentality. But whereas Purity connects grounding and Importantly, the premises of the argument from Settledness do not entail Purity*. As a result, the questionable character of Purity* every (not just some) fact X among F and FF, [F is grounded in FF] is less fundamental than XFor every thick grounding fact [F is grounded in FF] and sounds indeed compelling. However, these are only first impressions, and a proper assessment of the cogency of the argument requires at least prior specification of which key notions are involved.Settledness may not sound literally truistic, but it seems nevertheless very plausible. The stronger view thatThe discussion of Sect.\u00a0However, since the argument from Settledness involves the relative notion of being less fundamental than, the discussion of Sect.\u00a0absolute fundamentality have been reasonably thoroughly studied in the past few years, philosophical theorising on the connections between grounding, absolute fundamentality and relative fundamentality is greatly underdeveloped. As far as I know, there currently are only three reasonably elaborated views about these connections, one put forward in Bennett, F is fewer grounding steps away from the ungrounded fact(s) that terminate its unique grounding chain than G is from the ungrounded fact(s) that terminate its unique grounding chain;(2)F at least partially grounds G;(3)F stands in the ancestral of partial grounding to G;(4)F is ungrounded while G is grounded;(5)F belongs to some kind K and G belongs to some kind K* such thatNeither K nor K* includes both grounded and ungrounded members, andG does not belong to K and F does not belong to K*, andK*s are typically or normally grounded in Ks.Fact F is more fundamental than fact G \u2261Some parts of the second characterisation would require further elaboration in order to be fully clear, but we do not need to go into such details.18Bennett relativises fundamentality to \u201cbuilding relations\u201d, and she takes grounding to be among these relations. She holds that one can characterise, in terms of each such relation, both a notion of being fundamental and a notion of being more fundamental than. For grounding, the characterisations go as follows (see Ch. 5 and Ch.6):17(LF\u2192G)If a fact is less fundamental than another fact, then it is grounded.Putting the two characterisations together, we accordingly get Truism.Bennett\u2019s characterisation of absolute fundamentality trivially validates NF\u2009\u2192\u2009G. Moreover, a quick inspection of the five clauses of Bennett\u2019s characterisation of being more fundamental than reveals that each clause entails \u2018G is grounded\u2019. Accordingly, an immediate consequence of the characterisation is thatThe same diagnosis holds if Werner\u2019s  account df the holding of FF entails that F holds and is less fundamental than FF.F is grounded in FF \u2261The situation with Correia  is signiIn the original characterisation of factive grounding, \u2018entails\u2019 is left underspecified on purpose, in order to allow several precisifications among which one may make a choice. Various notions of entailment may indeed be deemed relevant for the purpose of characterising factive grounding. Of course, the same is true of non-factive grounding. Importantly, Grounding from Fundamentality does not entail LF\u2009\u2192\u2009G, and accordingly the previous considerations about Bennett\u2019s account and Werner\u2019s account do not apply to the account under focus.20In Correia , no accometaphysical necessitation, emergence only entails nomological necessitation  (A) is nothing but a consequence of the familiar view that facts expressed by atomic sentences are complex entities, composed of properties and relations and their exemplifiers. One may wish to argue in favour of (B) on the grounds that (u) if a fact is a component of another fact, then the former is less complex than the latter, and (v) less complex facts are more fundamental than more complex facts. However, one may accept (B) without accepting (v), e.g. because one do not believe that facts have degrees of complexity, or more generally because one do not believe that there is such a thing as a relation of being more complex than among facts.I previously claimed that the principle seems plausible. But what more could be said in its favour? Here is an argument that strikes me as having This argument in favour of Settledness can be attacked in various ways.immediate component instead of that of being a component:(A*) If F is grounded in FF, then F and FF are immediate components of [F is grounded in FF];(B*) Facts that are immediate components of other facts are more fundamental than them.(B*) is not subject to the counterexample to (B) discussed above, because G is not an immediate component of F \u2228 (G & \u00acG). Since (A*) and (B*) together entail Settledness , the modified principles can still be used to support Settledness, as announced.This counterexample to (B) suggests a modified argument in favour of Settledness, based on principles that are just like (A) and (B) but which invoke the concept of being an Of course, this amended argument in favour of Settledness does not escape all the objections to the original argument mentioned above, and accordingly a proper defence of the argument would require more work. But as far as my current purposes are concerned it is not necessary to push the discussion further. What is important is that the argument has been identified, because it can indeed be used to show that the views about relative fundamentality that I put forward in Correia  support The way I treat relative fundamentality there is indeed guided by the following principle, where the sentences in question are taken from certain regimented languages: if sentence S is an immediate part of sentence T, and if both sentences are true, then the fact expressed by S is more fundamental than the fact expressed by T.Let me wrap up the discussion of Correia . Purity (Order)(FF hold/s & F is grounded in FF) \u21d2 FF are/is more fundamental than [F is grounded in FF](Rigidity)If F is grounded in FF, then FF hold/s \u21d2 F is grounded in FF(Reflexivity)\u03c6 \u21d2 \u03c6(Transitivity)\u03c6 \u21d2 \u03c8, \u03c8 \u21d2 \u03c7 / \u03c6 \u21d2 \u03c7(&-Intro)\u03c6 \u21d2 \u03c8, \u03c6 \u21d2 \u03c7 / \u03c6 \u21d2 \u03c8 & \u03c7The following argument establishes that these five principles, together with Grounding from Fundamentality, yield the superinternality of grounding:Suppose that F is grounded in FF. By Rigidity, it follows that FF hold/s \u21d2 F is grounded in FF. By Reflexivity and &-Intro, we then get that FF hold/s \u21d2 (FF hold/s & F is grounded in FF). Thanks to Order and Transitivity, we can infer that FF hold/s \u21d2 FF are/is more fundamental than [F is grounded in FF]. By Grounding from Fundamentality, this means that [F is grounded in FF] is grounded in FF.The three logical principles are very weak. Order is very close to Settledness\u2014once Settledness is accepted, it is indeed hard to see how Order could be rejected (modulo acceptance of the relevant notion of entailment). As I emphasised, my views on relative fundamentality support Settledness. Rigidity is not obvious, and it is natural to think that it is the weakest link in the argument. However, note that given Grounding from Fundamentality, the principle follows from the following further principle about entailment:(Expansion)\u03c6 \u21d2 \u03c8 / \u03c6 \u21d2 (\u03c6 \u21d2 \u03c8)Expansion is not as weak as Reflexivity, Transitivity and &-Intro. It is not validated in the celebrated system R of relevant logic, for instance. Yet it is validated in systems that are much weaker than classical logic, e.g. in another celebrated system of relevant logic, RM, which can be axiomatised as R plus the Mingle axiom \u03c6 \u21d2 (\u03c6 \u21d2 \u03c6) , follows from Grounding from Fundamentality and from my approach to relative fundamentality, given certain assumptions about the logic of entailment. Consider the following five general principles, the first two about grounding and entailment and the last three only about entailment (symbolised as \u21d2):Let me wrap up the discussion of this section. Assuming Bennett\u2019s account of the connections between grounding and fundamentality\u2014more precisely, assuming her characterisation of being more fundamental than in terms of grounding, the argument from Settledness is dialectically ineffective because given that characterisation, the conclusion of the argument directly follows from Settledness. The same is true if Werner\u2019s account of being more fundamental than is assumed instead. By contrast, assuming the account of grounding in terms of being more fundamental than explored in Correia , the natTheorising about the connections between grounding, absolute fundamentality and relative fundamentality is in its infancy. So far, Bennett , Werner"}
{"text": "In the Calculating epidemiologically adjusted Ct values subsection of the Methods, there are a number of formatting errors in the sixth and ninth equations. Please view the complete, correct sixth equation here:In the Investigating variables associated with within-host viral burden subsection of the Results, there is an error on the third line of the second paragraph referencing"}
{"text": "The correct value is 3.39. The corresponding text [following eqn (1) in Section 3.1] should thus read:The authors regret that there was an arithmetical error in the calculation of the molar SiO4 (mAl) with m = 1\u20264, shown in Table 4, into eqn (1) yields SiO2/Al2O3 = 3.39 (Si/Al = 1.70) for the sodium aluminosilicate gel. This value is very close to the starting SiO2/Al2O3 ratio of RHA_3.5_1d ; together with the fact that the silica RHA had reacted only incompletely (degree of reaction: 89%) this shows that some of the Al from the sodium aluminate had not entered the sodium aluminosilicate gel.\u201d\u201cInsertion of the intensities of QThis change requires an additional minor change of a statement in the second paragraph of Section 3.2, which should read:2/Al2O3 ratio of its sodium aluminate gel was very similar to the overall SiO2/Al2O3 ratio of the starting mix and the complete reaction of the sodium aluminate, while the silica RHA had reacted only incompletely.\u201d\u201cThe occurrence of a separate aluminate phase in RHA_3.5_1d is in line with the above finding that the SiOAn independent expert has viewed the corrected data and has concluded that it is consistent with the discussions and conclusions presented.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Nature Plants 10.1038/s41477-022-01305-9. Published online 23 December 2022.Correction to: 2 sequestered by sinking seaweed in the ambient nutrient scenario were incorrect due to typographical errors. As a result, in the sentence beginning \u201cIn the optimistic case\u201d, \u201c0.85%\u201d is now \u201c0.110%\u201d, \u201c310,000 km2\u201d is now \u201c400,000 km2\u201d, and \u201cPoland\u201d now reads as \u201cZimbabwe\u201d. In the sentence following, \u201cis slightly higher: 0.036% and 0.099%\u201d now reads as \u201cis 0.035% and 0.100%\u201d and \u201c$40\u201d is now \u201c$30\u201d. Furthermore, in the penultimate sentence of this paragraph, \u201cocean areas of 0.09\u20130.10% and 0.28\u20130.37%\u201d now reads as \u201cocean areas of 0.085\u20130.100% and 0.285\u20130.410%\u201d and \u201croughly 320,000\u2013360,000\u2009km2 and 1,010,000\u20131,330,000\u2009km2\u201d is now \u201croughly 310,000\u2013360,000\u2009km2 and 1,030,000\u20131,480,000\u2009km2\u201d. Calculated values in this subsection have been revised to reflect these corrections: in the sentence beginning \u201cAverage costs at the median of Monte Carlo\u201d, \u201c$1,110\u2013$2,100\u201d is now \u201c$1,120\u2013$2,090\u201d; and in the paragraph beginning \u201cDespite being a small percentage\u201d, \u201c17%\u201d is now \u201c18%\u201d and \u201c61%\u201d is now \u201c64%\u201d. Corresponding values in the Methods subsection \u201cComparison of gigaton-scale sequestration area to previous estimates\u201d and in Supplementary Figures 10 and 11 have been updated accordingly. The errors have been corrected in the HTML and PDF versions of the article.In the version of this article initially published, in the Results subsection \u201cCosts and benefits of large-scale seaweed farming\u201d, the percentages of ocean area farmed to reach 1\u2009Gt and 3 Gt of CO"}
{"text": "After having been in contact with the authors, they agreed with the decision to retract the paper. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editor's attention by a concerned reader that certain of the cell migration and invasion assay data shown in Fig. 5C were strikingly similar to data appearing in different form in other articles by different authors at different research institutes, some of which have been retracted. Owing to the fact that the contentious data in the above article were already under consideration for publication, or had already been published, prior to its submission to"}
{"text": "Scientific Reports 10.1038/s41598-021-86716-y, published online 07 April 2021Correction to: The Acknowledgements section in the original version of this Article was incomplete. It now reads:\u201cThis research was funded by the following awards from the National Institute on Aging (NIA): K99 AG056599, R00 AG056599, P30 AG012846, T32 AG000221 (Schmitz), and P30 AG017266 (Lu and Schmitz). The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. The authors would like to thank Jason Fletcher, Rebecca Johnson, and Ramina Sotoudeh for helpful comments and feedback on earlier versions of this draft. This study deploys data from the Genetics Resource with the Health and Retirement Study (HRS), accession number phs000428.v2.p2.c1. These data were collected with financial support from the National Institute of Health\u2019s (NIH) Director\u2019s Opportunity for Research awards using American Reinvestment and Recovery Act funds . With these funds, the HRS has genotyped almost 20,000 respondents who provided DNA samples and signed consent forms in 2006\u20132012. The HRS data were produced and distributed by the University of Michigan under the directorship of David R. Weir, with funding from the National Institute on Aging (grant number NIA U01AG009470), Ann Arbor, MI. These data were accessed through dbGaP, under project number 14753 .\u201dThe original Article has been corrected."}
{"text": "This article has been retracted: Aging has completed its investigation of this paper. We found internal duplication and, although cropped differently, three tube formation assay images in Figure 5G were previously published as Figure 3C in a much older paper by different authors [ authors . As a reThe Administration of the Shanghai Chest Hospital, Shanghai Jiao Tong University was notified about the retraction by Aging Journal.. Original article: Aging. 2018; 10:2695\u20132708."}
{"text": "The term \u201cprognosis\u201d is used inaccurately throughout the article . The corIn the Introduction, a reference  has beenPLOS ONE Editors and the authors regret that these errors were not identified prior to publication.The"}
{"text": "Dear Editor1. We would be happy to elaborate further on the questions raised by the authors.We thank the authors for their comments on our studyWe agree with the authors that additional variables would be interesting to take into account for the primary outcome. In a statistical analysis, however, the number of confounders that can be included is limited. We therefore deliberately limited the number of confounders to those described to have the greatest potential effect on the primary and secondary outcomes.The authors point out that there were differences in baseline characteristics in terms of preoperative treatment, tumour location, and clinical nodal status. We included these possible confounders for the outcomes in our multilevel mixed statistical model. It could, therefore, be concluded that surgical approach was an independent factor associated with pneumonia, despite these differences in baseline characteristics.per se.Finally, we believe that a proficiency gain curve could have an effect on our results. As the data were anonymized, they were not sufficient to correlate the proficiency gain curve with postoperative outcomes. It should be noted, however, that all participating hospitals were high-volume centres and that the most experienced centres did not have the lowest anastomotic leakage rates"}
{"text": "Childhood injuries are the leading cause of death in children above the age of one , 2. Amonn = 18), lack of control for confounding factors that may have resulted in different treatment modalities being utilized, and medical management that is not representative of contemporary pTBI management. Unfortunately, there have been few studies since then on this topic. Those that have been conducted have largely been limited due to their retrospective nature and small sample size (Current Brain Trauma Foundation guidelines suggest that decompressive craniectomy (DC) is a potentially suitable therapeutic measure for certain patients with TBI . The eviple size , 11. Onlple size . In 2001High-quality multi-center RCTs focusing on pTBI are urgently needed. France is paving the way in this matter, having recently launched the \u201cDecompressive Craniectomy for Severe Traumatic Brain Injury in Children With Refractory Intracranial Hypertension\u201d (RANDECPED) trial . If the All authors listed have made a substantial, direct, and intellectual contribution to the work and approved it for publication.SB is funded by the National Institute for Health Research .The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher."}
{"text": "The revised version of"}
{"text": "The authors apologize for any potential confusion caused by the use of the phrase \u201cglucose bigotry\u201d in the original article.The phrase was employed to characterize a condition wherein the body encounters difficulty in regulating blood sugar levels, typically associated with prediabetes or diabetes. This condition signifies an impediment in the effective processing of glucose (sugar), resulting in elevated blood sugar levels.To improve the article the authors, correct the phrase \u201cglucose bigotry\u201d in line 2, section 3 to the well-recognized medical term \u201cglucose intolerance.\u201dThe authors would like to make apologies for any inconvenience caused."}
{"text": "Retraction Note: J Exp Clin Cancer Res 38, 475 (2019)10.1186/s13046-019-1433-3The Editor in Chief has retracted this article after concerns were raised regarding a number of potential image overlap issues. Specifically:It appears there are several potential image overlaps between Figs.\u00a02E and 4E of this article, despite the authors providing a correction to Fig.\u00a02 .Further potential image overlap has been alleged between Figs.\u00a01D and 6E of  by some Potential image overlap between 4B and 4B of  by some The authors were unable to provide raw images and evidence of ethical approval. Therefore, the Editor has lost confidence in the data presented here. All authors agree to this retraction."}
{"text": "Computational and Mathematical Methods in Medicine has retracted the article titled \u201cAnalysis of Clinical Characteristics of Hepatitis B and Alcohol-Related Liver Cancer\u201d [ Cancer\u201d  due to cFollowing an investigation conducted by the Hindawi Research Integrity team , signifiThe authors do not agree to the retraction."}
{"text": "Correction: Cell & Bioscience (2023) 13:10310.1186/s13578-023-01061-zIn this article, the email addresses of the authors Qun Wang & Zhencong Chen was swapped.Also, the authors Qihai Sui, Zhengyang Hu and Xing Jin should have been denoted as co-first authors."}
{"text": "The Royal Society of Chemistry is publishing this expression of concern in order to alert readers that concerns have been raised regarding the reliability of the XPS data in Fig. 5, the IPCE data in Fig. 6 (right) and the Nyquist data in Fig. 7. An investigation is underway, and an expression of concern will continue to be associated with the article until a final outcome is reached.Laura Fisher02/11/2023RSC AdvancesExecutive Editor,"}
{"text": "Retraction Note: Arthritis Res Ther 17, 145 (2015)https://doi.org/10.1186/s13075-015-0659-5The Editors-in-Chief has retracted this article because after the publication of the article concerns were raised about image overlap. Further investigation by the Publisher found the following concerns to be valid.Partial image overlap between Fig.\u00a01A  and Fig.\u00a02A Partial overlap between Fig.\u00a01A  and Fig.\u00a02A .Partial image overlap between Fig.\u00a02A  with Fig.\u00a06A Partial image overlap in Fig.\u00a02A  with Fig.\u00a05A  of\u00a0.Partial image overlap in Fig.\u00a03D  with Fig.\u00a06B  of\u00a0[The authors provided the raw data for validation. However, further checks by the Publisher identified some differences between the raw data and the figures, as well as overlap in raw images. The authors were unable to provide ethical approval for experiments involving Balb/c mice strain. The Editors-in-Chief therefore no longer has confidence in the presented data.Nadine Ruzehaji, Muriel Elhai, Jerome Avouac, Camelia Frantz, Joerg H. Distler and Yannick Allanore agree to this retraction. Maxime Frechet has not responded to any correspondence from the editor/publisher about this retraction. The editor was not able to obtain a current email address for Barbara Ruiz."}
{"text": "Hypertonic saline compared to mannitol for the management of elevated intracranial pressure in traumatic brain injury: a meta-analysis Han C, Yang F, Guo S and Zhang J. (2022) Front. Surg. 8:765784. doi: 10.3389/fsurg.2021.765784A Retraction of the Systematic Review Article The journal and Chief Editors retract the 07 January 2022 article cited above.Following publication, concerns were raised regarding abnormal similarities with the contents of other articles published by unrelated research groups. A subsequent investigation, which was conducted in accordance with Frontiers' policies, raised strong concerns over the authorship of the articles, resulting in a loss of confidence in the findings presented in the article.The authors have not responded to this retraction.This retraction was approved by the Chief Editors of Frontiers in Surgery and the Chief Executive Editor of Frontiers."}
{"text": "Sci., 2023, https://doi.org/10.1039/d3sc03514j.Correction for \u2018Liquid electrolyte chemistries for solid electrolyte interphase construction on silicon and lithium-metal anodes\u2019 by Sewon Park  The authors regret that there is an error in Section 3.1.2 of the original article. The correct sentence is shown below.Multilayer SEI structuring is further discussed in Section 3.3.3.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Clinical practice guidelines and Scientific statements are influential publications that define the standard of care for many diseases. However, little is known about industry payments and financial conflict-of-interest among authors of such publications in cardiology. We identified guidelines published between 2014 and 2020 by the American Heart Association (AHA) and the American College of Cardiology (ACC) in order to assess the payment status of CPG authors using the Open Payment Program (OPP) database. In recent years, there has been an increase in relationships with industry (RWI) in academia to conduct large, randomized trials of new medicines and technologies. While some level of RWI is necessary to test potential new advances in medical care, the National Academy of Medicine has published policies to regulate industry influence on the development of guidelines , since f2https://openpaymentsdata.cms.gov). We linked the OPP database with the National Plan and Provider Enumeration System (NPPES) database that contains physicians\u2019 National Provider Identifier in order to associate guideline authors to their respective payments (https://npiregistry.cms.hhs.gov/).We identified and reviewed both Clinical Practice Guidelines and Scientific Statements published between 2014 and 2020 by the American Heart Association (AHA) and the American College of Cardiology (ACC) by accessing the ACC and AHA guideline archives ,6. We exFirst, we reported descriptive statistics of industry payments received by guideline authors from 2014 to 2020, including all payment years for each guideline. We included all payment years to understand industry relationships prior to guideline development as well as payments received following publication, since 1) guidelines can take years from conception to publication and 2) authors may gain status and expertise following publication which can result in future speaking or consulting fees. Next, we assessed payments received by guideline authors within 2 years of guideline publication, since this approach may evaluate potential bias in guidelines more directly. Since annual industry payment data was unavailable in OPP until 2014, we limited this analysis to guidelines published between 2016 and 2020. We calculated the proportion of all guideline authors who received payments, the total value of payments, and the number of authors who received payments at the following levels: <$100; $100-$999; $1000-$9999; $10,000-$99,999; $100,000-$999,999; and >$1,000,000. We also calculated the annual percent change in the proportion of guideline authors who received payments and the median sum of payments per guideline. Finally, we evaluated whether FCOI disclosures made by guideline authors at the time of guideline publication correlate with OPP database records.3Among 578 physicians who co-authored 41 guidelines between 2014 and 2020, 169 (29%) received at least one industry payment. Payments to guideline authors totaled $16.8 million, or $29,107 per person . The proportion of authors with industry payments per guideline was 39% . Of authors who received payments, 82 (14.2%) received less than $10,000, whereas 38 (6.6%) received more than $100,000. These 38 authors accounted for $14.8 million, or 87.8% of total payments.Of the 430 physicians who co-authored 26 guidelines between 2016 and 2020, 102 (24%) authors received payments within 2 years of guideline publication. Payments made to guideline authors within 2 years of guideline publication totaled $4.3 million, or an average of $41,823 per person . The median percentage of authors per guideline who received payments within 2 years of publication was 21% . The number of authors receiving payments and the median value of payments per guideline are shown in 4Our study of relationships with industry among cardiology guideline authors from 2014 to 2020 had several findings that advance current understanding of physician relationships with industry. First, we found that approximately 40% of authors per guideline received industry payments over the study period, and 25% received payments within 2 years of guideline publication. AHA and ACC requirements state that no more than 50% of authors per guideline can have a FCOI, and that authors with FCOI are prohibited from voting on recommendations that involve products developed by companies with which they have FCOI. Our findings suggest that these goals are being met. Second, we found that the average payment for a guideline author $29,107) was around five times higher than previously reported average payments to all cardiologists (about $6500) [ was arouThis study has limitations. First, there may be inherent inaccuracies in payments reported by the OPP as well as limitations to OPP capture. As per OPP, payments made to any physician, physician assistant, nurse practitioner, clinical nurse specialist, certified registered nurse anesthetist, or certified nurse-midwife must be reported. Hence, any recipients of compensation who do not fall within these \u201ccovered recipients\u201d, as defined by OPP, are not accounted for. Second, we used comprehensive (rather than guideline-specific) FCOI information provided by guideline authors, which may overestimate the concordance rate between FCOI disclosure and industry payments. Third, non-monetary compensation such as food and beverage may not have been viewed as relationships with industry by guideline authors but are documented as OPP general payments, which may overestimate the discrepancy between FCOI disclosures and industry payments.Subhanik Purkayastha: Conceived and designed the experiments; Performed the experiments; Analyzed and interpreted the data; Wrote the paper. Ruina Zhang: Conceived and designed the experiments; Analyzed and interpreted the data; Wrote the paper. Xiaohan Ying: Conceived and designed the experiments; Contributed reagents, materials, analysis tools or data. Vinay Kini: Conceived and designed the experiments; Analyzed and interpreted the data; Contributed reagents, materials, analysis tools or data; Wrote the paper.Data will be made available on request.No additional information is available for this paper.The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper."}
{"text": "The above article, published online on September 28, 2018, in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement between the authors, the journal's Editor\u2010in\u2010Chief, Dr Stephen Tait, and John Wiley & Sons Ltd. The retraction has been agreed due to evidence of image duplication between figures 3D, 3E, and 6C and figures from articles published elsewhere in a different scientific context. As a result, the journal no longer has confidence in the results and conclusions.Zhang Z, Tan X, Luo J, Cui B, Lei S, Si Z, Shen L, Yao H. GNA13 promotes tumor growth and angiogenesis by upregulating CXC chemokines via the NF\u2010\u03baB signaling pathway in colorectal cancer cells. Cancer Med. 2018;7(11):5611\u20105620.  The above article, published online on September 28, 2018, in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement between the authors, the journal's Editor\u2010in\u2010Chief, Dr Stephen Tait, and John Wiley & Sons Ltd. The retraction has been agreed due to evidence of image duplication between figures 3D, 3E, and 6C and figures from articles published elsewhere in a different scientific context. As a result, the journal no longer has confidence in the results and conclusions.Zhang Z, Tan X, Luo J, Cui B, Lei S, Si Z, Shen L, Yao H. GNA13 promotes tumor growth and angiogenesis by upregulating CXC chemokines via the NF\u2010\u03baB signaling pathway in colorectal cancer cells. Cancer Med. 2018;7(11):5611\u20105620."}
{"text": "Respiratory Research (2020) 21:16110.1186/s12931-020-01426-9The Editors-in-Chief have retracted this article. Concerns with Fig.\u00a06B were previously addressed with a correction  but moreFigure\u00a02D: theShp(KO)\u2009+\u2009CS panel appears to partially overlap with the MK-2206\u2009+\u2009CS MMP-9 panel of Fig.\u00a02C in a previously published article [Figure\u00a05A: there appears to be a splice in the Pro-MMP-9 band.Figure\u00a07A: the JNK 1.25 and 2.5 blots appear to be identical to the JNK //- and +// blots in Fig.\u00a07B.The Editors-in-Chief therefore no longer have confidence in the results reported in this article.Authors Ya-nan Liu Jian Shen, Jian-cang Zhou, Hui-juan Shen, Qiang Shu, Qiang-min Xie and Yicheng Xie agree with this retraction. The other authors have not responded to correspondence regarding this retraction."}
{"text": "Retraction Note: BMC Complement Med Ther 15, 445 (2015)10.1186/s12906-015-0970-3The Editor has retracted this article because the authors have not been able to provide evidence that they obtained appropriate approval by an animal ethics committee for this study. In addition, Fig.\u00a04A  appears to overlap with Fig.\u00a04A (panel ERK 1/2) of ["}
{"text": "Traumatic crystallin lens dislocation is a common complication following open globe injuries. Wound repair, lensectomy, and prophylactic antibiotic administration are essentials in the management. In the ophthalmic examination, we found traumatic scleral rupture and subconjunctival crystallin lens dislocation  are defined as full\u2010thickness defects of the eyewall and are among the major public health problems in developing countries.2.1We summarized the management approach for a patient with OGI in Figure\u00a0Mehrdad Motamed Shariati: Conceptualization; investigation; project administration; supervision; writing \u2013 original draft; writing \u2013 review and editing. Seyedeh Maryam Hosseini: Data curation; supervision; writing \u2013 review and editing. Zeinab Hashemi Javaheri: Data curation; investigation.The authors received no funding.The authors declare that they have no competing interests.Written informed consent was obtained from the patient for the publication of this clinical image report."}
{"text": "Experimental Hematology & Oncology (2023) 12:7410.1186/s40164-023-00436-9After online publication of the article1, the authors noticed Table\u00a0The correct tables are published with this erratum."}
{"text": "Retraction Note: Molecular Medicine (2020) 26:3110.1186/s10020-020-00150-wThe Editor-in-Chief has retracted this article at the corresponding author\u2019s request. After publication, the authors became aware that the presented results could not be reproduced. Further checks by the publisher raised concerns regarding the animal models used in the study , as no information about this model is available from the stated supplier.All authors agree to this retraction."}
{"text": "The authors decided to retract this article, since some authors did not know the publication of the paper and the first author also disagreed with his personal ranking in the paper. The authors take full responsibility for these oversights, and apologize for any confusion or inconvenience that this may have caused to the readers, the journal, and the scientific community as a whole."}
{"text": "Following the publication of this article , concernIn Fig 4A the invasion assay vector and SOX2 panels appear similar to the invasion assay SOX2 and SOX2/si-Src panels found in Fig 7A respectively.\u25cb The H08910 cell MMP-2 panel and the Skov3 MMP-2 panel when rotated through 180 degrees.\u25cb The HO8910-pm NC p-P130cas (Y410) band and the Skov3 NC P130cas band when the latter is horizontally flipped.\u25cb The HO8910 SOX2 P130cas band and the Skov3 si-SOX2 P130cas band.\u25cb The HO8910 Vector MMP-9 band and the HO8910-pm si-SOX2 MMP-9 band.\u25cb The HO8910-pm NC GAPDH band and the Skov3 si-SOX2 GAPDH band.In Fig 6B the following bands appear similar:\u25cb The SOX2/si-SRC -/- p-P130cas (Y410) band and the HO8910 SOX2 P130cas band.\u25cb The SOX2/si-SRC +/- p-P130cas (Y410) band and the HO8910-pm NC p-P130cas (Y410) band.\u25cb The SOX2/si-SRC +/+ p-P130cas (Y410) band and the HO8910-pm si-SOX2 p-P130cas (Y410) band.In Fig 7B the following bands appear similar to bands found in Fig 6B:HO8910 cells are suspected of being HeLa derivatives rather than an ovarian cancer cell line .The authors stated that the similarity of panels in Fig 4A and 7A were due to errors made in the preparation of figures and provided images described as underlying data for these panels and a corrected version of Fig 4A. The authors provided some of the original data for Figs 6B and 7B but stated certain parts of the data were unavailable in addition to providing replication data. Due to the extensive nature of the concerns regarding Western blots in this article, the concerns regarding these figures can only be resolved via provision of original underlying data in its entirety for the published panels, which was not made available for editorial review. As such the PLOS Editors remain concerned about Figs 6B and 7B. The authors stated that concerns regarding the HO8910 cells were not known at the time of the study but did not provide data characterising the cells in question as ovarian cancer.PLOS ONE Editors retract this article.In light of the concerns affecting multiple figure panels that question the integrity and reliability of these data, the XW did not agree with the retraction. XJ, JC, DY, ZZ, QW, XX, and YF either did not respond directly or could not be reached."}
{"text": "Retraction Note: BMC Anesthesiology (2023) 23:21610.1186/s12871-023-02182-1The authors have retracted this article. After publication the authors realised that there was an error in the unit of oxygen consumption, the unit was listed as ml/kg/min, instead of 10\u2009\u2212\u20091 ml/kg/min. As this error affects all of the results and conclusions presented, the authors decided to retract the article. All authors agree to this retraction."}
{"text": "Correction: Mol Cancer 19, 99 (2020)https://doi.org/10.1186/s12943-020-01215-4Molecular Cancer entitled \u201cCircular RNA circCORO1C promotes laryngeal squamous cell carcinoma progression by modulating the let-7c-5p/PBX3 axis\u201d ), we identified minor errors in the images presented in Figs. In our research published  in MolecThe corrected Figs."}
{"text": "The authors wish to replace the \u2018Author Contributions\u2019 statement and the affiliation for Jochen Maurer of this article  with theAuthor Contributions: A.M. and F.M. supervised and administered the project. R.A.S., A.M. and F.M. contributed to the study conception and design. R.A.S. and J.P. analyzed and curated the data. A.T.J.V., A.C., S.T. and C.B. conducted chemical syntheses. R.A.S. and J.P. carried out the cell culture, experiments with cell lines, western blot experiments, microscopy and imaging. R.A.S. and M.B. performed statistical analyses. A.T.J.V., C.B., S.T., A.C. and J.M. provided material and resources. R.A.S., J.P., M.B., A.M. and F.M. interpreted the analyzed data. R.A.S. wrote the manuscript. A.M., M.B., F.M. and J.M. corrected the manuscript. All authors have read and agreed to the published version of the manuscript.Affiliation 5: Department of Gynecology and Obstetrics, University Hospital Aachen, RWTH Aachen University, 52074 Aachen, Germany.The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. The original article has been updated."}
{"text": "In the published article, there was an error in the affiliation list.Instead of \u201cUnit of Geriatrics and Internal Medicine, National Institute of Gastroenterology \u201cSaverio de Bellis\u201d, Research Hospital, Bari, Italy\u201d, authors Sara De Nucci, Martina Di Chito, Roberta Rinaldi and Giovanni De Pergola should be affiliated to \u201cUnit of Geriatrics and Internal Medicine, National Institute of Gastroenterology-IRCCS \u201cSaverio de Bellis\u201d, Castellana Grotte, Italy\u201d.Instead of \u201cUnit of Data Sciences and Technology Innovation for Population Health, National Institute of Gastroenterology \u201cSaverio de Bellis\u201d, Research Hospital, Bari, Italy\u201d, authors Fabio Castellana, Roberta Zupo, Luisa Lampignano and Rodolfo Sardone should be affiliated to \u201cUnit of Data Sciences and Technology Innovation for Population Health, National Institute of Gastroenterology-IRCCS \u201cSaverio de Bellis\u201d, Castellana Grotte, Italy\u201d.Instead of \u201cDepartment of Gastroenterology, National Institute of Gastroenterology \u201cSaverio de Bellis\u201d, Research Hospital, Bari, Italy\u201d, authors Vito Giannuzzi and Raffaele Cozzolongo should be affiliated to \u201cDepartment of Gastroenterology, National Institute of Gastroenterology-IRCCS \u201cSaverio de Bellis\u201d, Castellana Grotte, Italy\u201d.Instead of \u201cScientific Direction, National Institute of Gastroenterology \u201cSaverio de Bellis\u201d, Research Hospital, Bari, Italy\u201d, author Gianluigi Giannelli should be affiliated to \u201cScientific Direction, National Institute of Gastroenterology-IRCCS \u201cSaverio de Bellis\u201d, Castellana Grotte, Italy\u201d.The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated."}
{"text": "Following the publication of this article , concernSpecifically:In Fig 2B, AKAP LBC V5 panel band 1 appears similar to band 4 when horizontally flipped.\u25cb Bands 1, 2, and 4 of the AKAP Lbc V5 panel appear similar when band 2 is horizontally flipped. Additionally, these bands appear similar to band 1 in the AKAP Lbc V5 panel in Fig 2C.\u25cb When levels are adjusted to visualize the background, there appear to be vertical discontinuities in the AKAP Lbc V5 panel between lanes 1 and 2 and lanes 3 and 4.In Fig 2D:The authors stated that the underlying data for the figures of concern could not be recovered, as the Carnegie lab, which conducted these experiments, closed following his death in 2014. Regarding the concern in Fig 2B, the authors provided a raw blot from a replicate experiment corroborating the data provided in the published panel. The authors additionally provided individual level data for the RHO-Gef and PKA activity assays in Fig 2, but were unable to provide the original underlying data for the blots in Fig 2C and 2D. The PLOS Editors remain concerned about the unresolved issues in these panels.PLOS ONE Editors retract this article.In light of the concerns affecting multiple panels in Fig 2 that question the reliability of these data, the The corresponding author noted that GC is deceased. MJSpindler, BTB, ECH, NS, DS, and BRC agreed with the retraction. YH and MJScott either did not respond directly or could not be reached."}
{"text": "There were missing figures and associated legends for There was an error in the original publication . The figSection 4.1, First Paragraph and Second Paragraph:A correction has been made ton = 3\u20137 out of a population of 50,000 conformers for sphingosine [M+H]+. MC sampling was run for 1,000,000 iterations for each n-sized set, with each taking more than 2 h to complete. After loading the data matrix, which required about 3 min, the heuristic algorithm found all sets in <1 min. SDS also had a greater RMSD log-sum  for every set size, as shown in SDS was shown to be faster and produce more dissimilar sets than a Monte Carlo (MC) sampling method in a contest to find the most dissimilar sets of +, with similar results. Here, MC performed better than SDS at n = 3 by a small margin (n < 50,000 in approximately 7 min, including the approximate 3 min required to load the matrix.This benchmarking analysis was applied again to 50,000 conformers of methyleugenol [M+Na]l margin . SDS ran2.Section 4.2, First Paragraph:N = 20, 22, and 24 with n = N/2 used on randomly generated datasets, as summarized in SDS was benchmarked against the exact solution for The authors state that the scientific conclusions are unaffected, and we acknowledge that these figures were part of the original review. This correction was approved by the Academic Editor, and have already been approved by the reviewers. The original publication has also been updated."}
{"text": "In an articleThe correct statement is shown below:\u201cThere are no conflict of interests in this research.\u201dThe authors apologize for the error."}
{"text": "Retraction Note: J Exp Clin Cancer Res 35, 100 (2016) 10.1186/s13046-016-0379-yThe Editor-in-Chief has retracted this article. Concerns were raised regarding a number of figures, specifically:Figure\u00a02d: the TRIM11 NCI-H446 band appears to be identical to the PCNA band of Fig.\u00a05C in an article by different authors that was simultaneously under consideration with another journal [Figure\u00a05a: the p-AKT band appears to be identical to the the STK39 NCI-H358 band of Fig.\u00a03C in an article by different authors that was simultaneously under consideration with another journal .The Editor-in-Chief therefore no longer has confidence in the results and conclusions reported in this article.Authors Yusheng Shu has not responded to correspondence regarding this retraction. The Publisher has not been able to obtain a current email address for authors Xiaolin Wang, Weiping Shi, Hongcan Shi, Shichun Lu, Kang Wang, Chao Sun, Jiansheng He, Weiguo Jin, Xiaoxia Lv and Hui Zou."}
{"text": "There are errors in the Funding section. The correct Funding statement is: This research is partially funded by Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico (CNPQ) and Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de Minas Gerais (FAPEMIG). The authors and grant numbers are as following: Amir Khatibi: (CNPq: 169823/2017-2); Ana Paula Couto da Silva and Marcos A. Gon\u00e7alves: , ; Jussara Almeida: (CNPq: 305683/2019-5 and 403106/2021-4). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.The publisher apologizes for the error."}
{"text": "Specifically, a change in the multi-threading factor resulted in fewer permutations generated for the null distribution than had been preregistered, which were then divided incorrectly. This affected only the movie-wide tests (not associations with suspense). The authors have corrected this error and rerun their analyses, which did not change statistical inference.The authors discovered an error in their code for deriving p values in the Movie-wide Connectivity Tests section of the Results required updating. These p values all remained nonsignificant, leaving the overall results and interpretations unaffected.As a result of this error, the 6 reported p values have been corrected in the final paginated version of this article.The"}
{"text": "The journal retracts the 2022 article cited above.Following publication, concerns were raised regarding the contributions of the authors of the article. Our investigation, conducted in accordance with Frontiers policies, confirmed a serious breach of our authorship policies and of publication ethics; the article is therefore retracted.This retraction was approved by the Chief Editors of Frontiers in Psychology and the Chief Executive Editor of Frontiers. The authors have not responded to correspondence regarding this retraction."}
{"text": "There are errors in the Funding section. The correct Funding statement is: This project was carried out within the framework of the priority program SPP 2089: \u201cRhizosphere spatiotemporal organization\u2014a key to rhizosphere functions\u201d funded by the Deutsche Forschungsgemeinschaft \u2014Project number 403641683 (RI-903/7-1). Hans Hermann Richnow (HHR) received the fund for this project from DFG. This work was conducted at ProVIS Centre for Chemical Microscopy  und dem Freistaat Sachsen Program) at Helmholtz Centre for Environmental Research\u2014UFZ.The authors apologize for this error and state that this error does not affect the results, conclusions, and overall scientific understanding of the article in any way."}
{"text": "BMC Psychology (2023) 11:35810.1186/s40359-023-01342-9Following publication of the original article, the authors flagged that in the Questionnaires subsection of the Methods the \u2018phi\u2019 symbol had erroneously been used instead of the \u2018omega\u2019 symbol in the following (now correct) instances:\u03b1=0.88 and \u03c9=.92.\u03b1=0.82 and \u03c9=0.91 for trait FoMO, and \u03b1=0.89 and \u03c9=0.92 for state FoMO\u03b1=0.90 and \u03c9=0.92 for presence of meaning in life (Presence), and \u03b1=0.96 and \u03c9=0.97 for search for meaning in life (Search).The published article has been corrected. The authors thank you for reading this erratum and apologize for any inconvenience caused."}
{"text": "The journal retracts the 2022 article cited above.Following publication, concerns were raised regarding the contributions of the authors of the article. Our investigation, conducted in accordance with Frontiers policies, confirmed a serious breach of our authorship policies and of publication ethics; the article is therefore retracted.This retraction was approved by the Chief Editors of Frontiers in Chemistry and the Chief Executive Editor of Frontiers. The authors have not responded to correspondence regarding this retraction."}
{"text": "Funding statement. The correct Funding statement appears below.In the published article, there was an error in the \u201cThis work was funded by the European Regional Development Fund (ERDF) through COMPETE 2020, Portugal 2020 and by FCT (Funda\u00e7\u00e3o para a Ci\u00eancia e Tecnologia), ([POCI-01-0145-FEDER-030985 and POCI-01-0145-FEDER-016385]) and by FCT/Minist\u00e9rio da Ci\u00eancia, Tecnologia e Inova\u00e7\u00e3o in the framework of individual funding [CEECINST/00091/2018] to DN and by QREN funds through the project ClinUCX (QREN 30196) and individual fellowships: [PD/BD/127997/2016] to TL, [SFRH/BD/144490/2019] to RG [SFRH/BD/111799/2015] to VS-P. The funding bodies other than ECBio had no role in design, in the collection, analysis, and interpretation of data; in the writing of the manuscript; or in the decision to submit the manuscript for publication.\u201dConflict of interest statement. The correct Conflict of interest statement appears below.Also, the role of funder ECBio S.A. was missing from the \u201cHC and PC were shareholders of ECBio S.A. JS and RB were employees of ECBio S.A.The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.The authors declare that this study received funding from ECBio S.A. The funder had the following involvement in the study: provided all cell batches required for the studies.\u201dThe authors apologize for these errors and state that this does not change the scientific conclusions of the article in any way. The original article has been updated."}
{"text": "After this article  was publMultiple sections of the CA IV panels in Fig 1a in  but the In Fig 1b, there appear to be similarities between two sets of two areas within the left CA IV panel.During editorial follow-up on these issues, the authors stated that the histochemical images in Fig 1a in  may havePLOS ONE Editorial Board reviewed the concerns and authors\u2019 responses, and advised that whilst repetitive transverse lines are expected for this type of experiment due to the striated pattern of transverse tubules, different images or different regions within an image would not be expected to have the level of similarity observed in these figures.A member of the PLOS ONE Editors retract this article.Without the original images we cannot resolve the concerns about the integrity and reliability of results reported in Fig 1. Therefore, the GG, SP, and RJS did not agree with the retraction. JH, AW, WSS, PW, and VE either did not respond directly or could not be reached."}
{"text": "Nature Communications 10.1038/s41467-018-07998-x published online 10 January 2019Retraction to: The authors have retracted this article due to multiple imaging errors across several figures which call into the reliability of the data and the conclusions. In particular, we note there were errors in the colony formation images , migration images , western blots  and histology . In addition, at the time of publication some experiments were lacking biological repeats  We apologise for any inconvenience caused to the community. Qingling Zhang has stated on behalf of all authors that they agree to this retraction."}
{"text": "Pages 1014 and 1016. The list of authors has been updated to includePaul G. Wyatt, whose information is as follows:Paul G.Wyatt \u2013 Drug Discovery Unit,Wellcome Centre for Anti-Infectives Research, School of Life Sciences,University of Dundee, Dundee DD1 5EH, U.K.; orcid.org/0000-0002-0397-245X"}
{"text": "Correction:J Exp Clin Cancer Res42, 284 (2023)https://doi.org/10.1186/s13046-023-02848-1In Fig.\u00a0In Fig.\u00a0In Fig.\u00a0In the main text, the tumor clearance efficiency of PRV-LAV in the CT26 model is 50%, not 40%.n\u2009=\u20099), not (n\u2009=\u20096).In the legend of Fig.\u00a05, the number of mouse in Fig.\u00a05I is (n\u2009=\u20095)\u201d should be (n\u2009=\u20096).In the description of animal experiments in the Materials and Methods section, the sentence \u201cAge matched (14 to 16-week-old) na\u00efve mice were used as controls (Following publication of the original article , errors The correct Figs."}
{"text": "The authors wish to make the following corrections to this paper :Ms. Paraskevi Kogionou (P.K.) was not included as a first co-author in the original publication. The corrected Author Contributions Statement appears here.Conceptualization, C.N.B.; Data curation, P.K. S.P.F., M.G., P.B. and S.S.; Formal analysis, P.K., S.P.F., M.G., N.A., P.B. and S.O.; Funding acquisition, C.N.B.; Investigation, P.K., S.P.F., M.G., P.B., D.C., G.M., S.S. and A.D.G.; Methodology, P.K., S.P.F., M.G. and S.S.; Project administration, C.N.B.; Resources, S.S., D.C., G.M. and C.N.B.; Supervision, C.N.B.; Validation, P.K., S.P.F., M.G., G.M. and C.N.B.; Visualization, P.K., S.P.F., M.G., N.A. and S.O.; Writing\u2014original draft, P.K., S.P.F., M.G. and C.N.B.; Writing\u2014review and editing, S.P.F., M.G., N.A., G.M., S.S., A.D.G. and C.N.B. All authors have read and agreed to the published version of the manuscript.The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "Retraction Note: BMC Cancer (2020) 21:210.1186/s12885-020-07670-yThe Editors have retracted this article due to the authors\u2019 inability to provide documentation of approval from the ethics committee. The authors have not responded to correspondence from the publishers about this retraction."}
{"text": "Due to a publishing error the article: \u201cStem cell-derived exosomes from human exfoliated deciduous teeth promote angiogenesis in hyperglycemic-induced human umbilical vein endothelial cells\u201d, published at Journal of Applied Oral Science 31(e-20220427):1-13. doi: 10.1590/1678-7757-2022-0427 was printed with the following error:Where it reads:AcknowledgmentsThe authors thank Natthapatt Sooppapipatt, Pitchaporn Teacharushatakit, Wifada Powattanasuk, and Chareerut Phruksaniyom for their technical assistance. Moreover, the authors thank Enago (www) for the English language review.The sentence should read:AcknowledgmentsThe authors thank Natthapatt Sooppapipatt, Pitchaporn Teacharushatakit, Wifada Powattanasuk, and Chareerut Phruksaniyom for their technical assistance. Moreover, the authors thank Enago (www) for the English language review.This research work is supported by Mahidol University ."}
{"text": "Retraction note: Nanoscale Research Letters (2020) 15:139https://doi.org/10.1186/s11671-020-03357-2The Editors in Chief have retracted this article. After publication, concerns were raised around a seeming partial overlap within images presented in Fig.\u00a01C as well as in multiple panels in Figs.\u00a02C, D, E. The authors provided partial data, but were unable to provide uncropped, original files. The Editors in Chief, therefore, have lost confidence in the integrity of the article's findings. None of the authors agree to this retraction."}
{"text": "Sci., 2023, 14, 9101\u20139113, https://doi.org/10.1039/D3SC02492J.Correction for \u2018The need for  The authors regret that the Acknowledgements section of the original article was incomplete. The complete acknowledgements are shown in the following text:Charles University Centre of Advanced Materials (CUCAM)  is acknowledged. This work was supported by the Ministry of Education, Youth and Sports of the Czech Republic through the e-INFRA CZ (ID: 90254). The authors acknowledge the Czech Science Foundation through projects 20-12099S  and 23-07616S . CJH and LG acknowledge support from the Charles University Centre of Excellence award UNCE/SCI/014. The authors acknowledge Daniel Willimetz for additional generalization tests and the verification of ML methods.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "This article has been corrected: The authors found an error in Figure 6C. Three images of immunostaining for PKH26, p-ERK and Merge in the co-culture transwell experiment  from the ARP1 cell line were misrepresented as the CAG cell line. The authors corrected the error with representative images of PKH26, p-ERK and Merge in CAG cells from the original experiments. Correspondingly, the quantitative results for the CAG cell line in Figure 6D were revised based on the replaced images. The presented corrections do not affect the results or conclusions of this article. The authors would like to apologize for any inconvenience caused.Figure 6 is presented below.Corrected"}
{"text": "BMC Cancer 14: 677, 2014].Following the publication of this paper, it was drawn to the Editor's attention by a concerned reader that the tumour images shown in Fig. 7A and certain of the cell proliferation assay images shown in Fig. 3B were strikingly similar to data that had already appeared in another article written by different authors at different research institutes [Xiao W Wang, J, Li H, Xia D, Yu G, Yao W, Yang Y, Xiao H, Lang B, Ma X Oncology Reports, the Editor has decided that this paper should be retracted from the Journal. The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Owing to the fact that the contentious data in the above article had already been published prior to its submission to"}
{"text": "Retraction Note: J Ovarian Res 15, 115 (2022)\u200310.1186/s13048-022-01043-8The Editors-in-Chief have retracted this article at the corresponding author\u2019s request. After publication, concerns were raised regarding high similarity between the images presented in Fig.\u00a03B, D, E and F, and those previously published by different authors in Fig.\u00a01C of [Sagar Chhabria has not responded to any correspondence from the editor or publisher about this retraction. All other authors agree to this retraction."}
{"text": "The purpose of this study was to compare electromyographic (EMG) with mechanomyographic (MMG) recordings during isometric conditions, and during a simulated load-lifting task. Twenty-two males (age: 25.5 \u00b1 5.3 years) first performed maximal voluntary contractions (MVC) and submaximal isometric contractions of upper limb muscles at 25%, 50% and 75% MVC. Participants then executed repetitions of a functional activity simulating a load-lifting task above shoulder level, at 25%, 50% and 75% of their maximum activity (based on MVC). The low-frequency part of the accelerometer signal (<5 Hz) was used to segment the six phases of the motion. EMG and MMG were both recorded during the entire experimental procedure. Root mean square (RMS) and mean power frequency (MPF) were selected as signal extraction features. During isometric contractions, EMG and MMG exhibited similar repeatability scores. They also shared similar RMS vs. force relationship, with RMS increasing to 75% MVC and plateauing to 100%. MPF decreased with increasing force to 75% MVC. In dynamic condition,  Today, measuring muscle activity in ecological situations is a major issue. It could allow a better understanding of the neuromuscular system and its adaptations to the environment compared to isolated contractions in the laboratory. It may also have significant applications. In sports science, assessing muscle load may enhance performance optimization strategies, injury prevention monitoring and rehabilitation. In physical ergonomics, muscle evaluation can help reduce work-related musculoskeletal disorders through workplace assessment and reconception . In humaTo effectively measure muscle activity in functional and ecological situations, the method used should be easy to set up and to use, and robust in all environments and during prolonged duration acquisitions. Today, the reference method for muscle activity measurement is electromyography (EMG), which measures the electrical activity of muscles. However, it requires skin preparation and a precise sensor placement for reproducible results ,3, makinOther techniques have emerged for recording muscle activity such as mechanomyography (MMG), the mechanical counterpart of EMG, which is the measurement of the low-frequency lateral oscillations of active muscle fibers . MMG refrtifacts . Thus, wrtifacts . Recentlrtifacts ,12. Beinrtifacts , making MMG appears to have a number of advantages over EMG such as no skin preparation, ease of fixation and less sensitivity to sensor placement , making Despite a great number of studies regarding isometric and isokinetic contractions, very little MMG literature characterizes MMG under poly-articular functional activities such as squatting ,13. To tThus, the objectives of this study are twofold: (i) comparing a new accelerometer-based MMG system to an EMG reference system during isometric contractions and (ii) analyzing a load-lifting task with both MMG and EMG to explore MMG applications during complex dynamic conditions.Only male subjects were selected in this study for gender considerations . ParticiTwenty-two active males  participated in this study. All subjects turned out to be right-handed. Participants provided written informed consent before taking part in this experiment. This study was approved by the Academic Research Ethics Committee .EMG signal was recorded using sensors  sampled at 2000 Hz and positioned following the SENIAM recommendations . A forceThe isometric testing procedure comprised two parts: (i) the measurement of the maximum voluntary contraction (MVC) of the Biceps Brachii (BB), Triceps Brachii (TRI) and the lateral Deltoid (DEL) muscles, and (ii) the submaximal contractions at 25%, 50% and 75% of MVC for each muscle.For the MVC measurements, participants had to perform three maximal contractions of 3 s onto the force sensor attached to an adjustable metallic structure. Trials were separated by two-minute rest periods. For the BB and the TRI muscle, the participant had the elbow flexed at 90\u00b0 against the body and the force sensor was placed on the wrist. The force sensor was facing downward for the BB and upward for the TRI. For the DEL muscle, the arm was extended forward parallel to the ground with the force sensor on top of the wrist facing downward. For each muscle, the MVC value was defined as the highest value obtained across the three trials .The participant then had to maintain submaximal contractions at 25, 50 and 75% of MVC for 15 s, thanks to a visual feedback of force level displayed on a screen. Each submaximal contraction was repeated three times, with a 1.5-min rest period.The dynamic testing consisted of 10 repetitions of a load lifted above shoulder level with both hands. The different weights of the load were derived from the MVC obtained for the BB muscle in the isometric condition. More precisely, the force obtained during MVC was converted into a mass to lift . Indeed, BB was chosen over TRI and DEL muscles as a reference because it was the strongest muscle of the three and thus allowed to have the largest load differences between intensities. Each repetition started with lifting the charge from the mid-tibia level to above shoulder level and getting back into the initial position see . The parEMG and force signals were collected through the QTM software version 2022  allowing their synchronization. MMG signal was obtained using another software . EMG and MMG signals were band-pass filtered between 20\u2013500 Hz , respectFor the isometric testing procedure, each trial was segmented to select the 33% middle part of the contraction time according to previous studies ,17,18,19The amplitudes of EMG and MMG signals were calculated by taking the root mean square (RMS) value of the segmented portion. The RMS values from EMG and MMG for each muscle were normalized from the average RMS values obtained during the three MVC trials . The stu content .X, Y and Z represent the 3 axes of the accelerometer.quations  and 2),,RMSMMG aX, Y and Z represent the 3 axes of the accelerometer.For the dynamic testing, the accelerometer was first low-pass filtered at 5 Hz to keep only the motion data (MOT), which is composed of low frequency accelerations . We usedEquation :(3)\u03b8=arcFor the isometric testing, repeatability tests of absolute ndations . RepeateFor the dynamic testing, an ICC  was conducted in order to quantify the repeatability of the MOT data over intensity levels for each muscle. Because EMG and MMG signals were not normalized in dynamic condition, two-way repeated measure ANOVAS ; however, there were no RMS differences between 50% and 75% MVC for phase 2 and between 25% and 50% MVC for phase 5. For TRI, RMS values were only different between 25% and 75% MVC for phase 3 (concentric contraction). For DEL, RMS values were different from each other except between 50% and 75% MVC for phase 3 (concentric contraction) see .For MMG, there was no difference in RMS between concentric and eccentric phases for the BB muscle for all intensity levels. For the TRI and DEL muscles, RMS during the concentric contraction (phase 3) was lower than the eccentric part (phase 4) for 50% and 75% MVC.For EMG, there was no difference in RMS between concentric and eccentric phases for the BB and TRI muscles for all intensity levels. For the DEL muscle, RMS values during its concentric contraction was greater than the eccentric contraction for all intensity levels  .Finally, the main result of this study concerns the fact that MMG was more sensitive to changes in load than EMG in dynamic condition. MMG amplitude exhibited greater systematic effect sizes of intensity in ANOVAs and significantly greater correlations with load for the BB and TRI muscles. A similar result has been found during incremental cycling, for which authors exhibited that \u201cMMG amplitude more closely reflects changes in power output\u201d .In this study, ondition ,32.One of the limits of this study is the absence of EMG and MMG normalization in dynamic conditions. Because MMG amplitude is greater in dynamic condition compared to isometric condition , we coulove 5 Hz . Even ifove 5 Hz ,12,36. OTo the best of our knowledge, this study was the first to investigate MMG and EMG during a functional load lifting task at different intensities. This study widens the scope of MMG knowledge in the context of functional activities. During isometric conditions, EMG and MMG had excellent repeatability scores, as well as similar RMS and MPF vs. force relationship. During a dynamic situation corresponding to a load-lifting task, RMS from the MMG signal was more sensitive to changes in load than EMG signal. Conversely, MPF from the EMG signal was more sensitive to changes in load. Altogether, these results sustain the feasibility of using MMG measurement in complex functional activities, such as load lifting and carrying. Moreover, EMG and MMG signals may be used together to give complementary information concerning strategies of motor unit recruitment, in both time and frequency domains. This study highlighted the fact that MMG signal may be used for practical applications such as in sports science or physical ergonomics assessment. Further work is now necessary in terms of signal processing to improve the reliability of MMG signal during ecological conditions."}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Owing to the fact that some of the data in the above article had already been published, or were under consideration for publication, prior to its submission to"}
{"text": "Following publication, concerns were raised regarding the integrity of Figures\u00a03L, 5A, 5B, 5C and 6A. The authors failed to provide a satisfactory explanation during the investigation, which was conducted in accordance with Frontiers\u2019 policies. As a result, the data and conclusions of the article have been deemed unreliable and the article has been retracted.This retraction was approved by the Chief Editors of Frontiers in Oncology and the Chief Executive Editor of Frontiers. The authors have not responded to correspondence regarding this retraction."}
{"text": "Sci.2022, 9, 2202550Advanced Science, published online on 5 June 2022 in Wiley Online Library (https://onlinelibrary.wiley.com/doi/full/10.1002/advs.202202550), has been retracted by agreement between the authors, the Editor\u2010in\u2010Chief, Kirsten Severing, and Wiley\u2010VCH GmbH. The retraction has been agreed as the article is based on research results and data that the authors were not authorized to use. Moreover, the majority of co\u2010authors have been listed despite insufficient qualification for contributorship.The above article from  Sci.2022, 9, 2202550Advanced Science, published online on 5 June 2022 in Wiley Online Library (https://onlinelibrary.wiley.com/doi/full/10.1002/advs.202202550), has been retracted by agreement between the authors, the Editor\u2010in\u2010Chief, Kirsten Severing, and Wiley\u2010VCH GmbH. The retraction has been agreed as the article is based on research results and data that the authors were not authorized to use. Moreover, the majority of co\u2010authors have been listed despite insufficient qualification for contributorship.The above article from"}
{"text": "Mater. Chem. C, 2023, 11, 4867\u20134875, https://doi.org/10.1039/d2tc05390j.Correction for \u2018Heads or tails: investigating the effects of amphiphile features on the distortion of chiral nematic liquid crystal droplets\u2019 by Lawrence W. Honaker  The authors regret an error in The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Furthermore, they apologize to the readership for any inconvenience caused.The revised versions of"}
{"text": "Retraction Note: J Exp Clin Cancer Res 38, 189 (2019)10.1186/s13046-019-1193-0The Editor-in-Chief has retracted this article. After publication, concerns were raised regarding the data presented in the figures. Specifically:In Fig.\u00a03e, the right image appears highly similar to Fig.\u00a03e left in .In Fig.\u00a03c, plot 1 appears highly similar to plot 2, and plot 3 appears highly similar to plot 6.LV-control in Fig.\u00a05d appears highly similar to shRNA control in Fig. S2b.Additionally, the authors used SMMC-7721, QGY-7703 and L02 cell lines, which have been reported to be contaminated with HeLa cells.The authors have stated that the data duplication was caused by simple errors, and the overlap with  occurredDue to the high number of image concerns and the use of unsuitable cell models for hepatocellular carcinoma, the Editor-in-Chief no longer has confidence in the presented data.Hongda Ding agrees to this retraction. Junpeng Liu, Ruoyao Zou, Pengrui Cheng and Yang Su have not responded to any correspondence from the editor or publisher about this retraction."}
{"text": "Sci., 2023, https://doi.org/10.1039/d2sc06040j.Correction for \u2018Radical ring-opening polymerization of sustainably-derived thionoisochromanone\u2019 by Emily A. Prebihalo  The authors regret that incorrect details were given for ref. 28 in the original article. The correct version of ref. 28 is given below as ref. The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "The authors apologize for any confusion this may have caused."}
{"text": "Biol. Open (2017) 6, 252-259 (doi:10.1242/bio.021774).There was an error published in The image from the si-HIF-1\u03b1 group in Fig 4E was inadvertently duplicated in the mimics NC group in Fig 1G. Replicate SW1990 panels have been substituted. The corrected In addition, there is a possible duplication of the mimics NC and inhibitor NC HIF-1\u03b1 blots in Fig 2B. The authors no longer have the original data for these blots, but state that new data from repeated experiments (not shown) is consistent with the results reported in the paper. The additional data are available from the authors upon reasonable request.The authors apologise to readers for these errors, which do not impact the results or conclusions of this paper."}
{"text": "PNAS Nexus, Volume 2, Issue 5, May 2023, pgad146, https://doi.org/10.1093/pnasnexus/pgad146This is a correction to: Jon Green, James N Druckman, Matthew A Baum, Katherine Ognyanova, Matthew D Simonson, Roy H Perlis, David Lazer, Media use and vaccine resistance, PNAS Nexus, it was discovered that this paper was missing a statement acknowledging compliance with the PNAS Nexus Human and Animal Participants and Clinical Trials policy:During a retroactive audit conducted by All data collection and procedures in this manuscript were approved by the institutional review boards at Northeastern (#20-04-12), Rutgers (#Pro2020000977), and Harvard (#IRB20-0593) Universities. All participants in the study provided their informed consent.This error has been corrected in the original article."}
{"text": "Page 1: This article was published with Yasemin Topal Y\u00fcksel\u2019s surname misspelled as \u201cY\u00fcsel\u201d in the byline. The name should appear as given in this Erratum.Volume 7, issue 1, e00917-21, 2022, https://erda.ku.dk/archives/df76280733e748cac433f8ef28e558ab/published-archive.html).\"Page 12, \u201cBioinformatics\u201d paragraph 1: The last sentence should read \"Reads from samples and extraction negatives are freely available for download from the University of Copenhagen\u2019s Electronic Research Data Archive ("}
{"text": "Retraction to: Virology Journal 2010, 7:26http://www.virologyj.com/content/7/1/26The Editor in Chief has retracted this article because of multiple concerns about image overlaps, namely:Rows A1 and B1 of Fig.\u00a02 appear similar;The three last blots in line B4, Fig.\u00a01 and line B4, Fig.\u00a02 appear to be repeating;The first two blots in lines A2 and A3. Fig, 2, appear to be repeating;Rows B1 and B6 in Fig.\u00a03 appear similar.The authors did not respond to a request for clarification nor to correspondence from the Editor about this retraction."}
{"text": "Scientific Reports 10.1038/s41598-022-10304-x, published online 20 April 2022Correction to: The Acknowledgements section in the original version of this Article was incomplete.\u201cThis manuscript resulted from a project financially supported by CAMM, the Center of Advanced Mining and Metallurgy, as a center of excellence at the Lule\u00e5 University of Technology. The authors also thank Solenis for their help with the reagents used as grinding aids in this study. The authors express their gratitude to Dr. Andras Gorzsas from Ume\u00e5 University for assistance with FTIR analysis and fruitful discussions.\u201dnow reads:2, the Center of Advanced Mining and Metallurgy, as a center of excellence at the Lule\u00e5 University of Technology, and Vinnova for the RIO-MUN , project number: 2020-04835. The authors also thank Nouryon (Sweden) and Solenis for their help with the reagents used in this study. The authors express their gratitude to Dr. Andras Gorzsas from Ume\u00e5 University for assistance with FTIR analysis and fruitful discussions.\"\"This manuscript resulted from a project financially supported by CAMMThe original Article has been corrected."}
{"text": "The authors would like to make a correction in a recently published paper .Error in FigureIn the original publication, there was a mistake in:(1) n2 \u2212 1)\u22121 versus (h\u03c5)2 for Sex60\u2212Ge35Ga5Sbx thin films. as published.(2) The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected."}
{"text": "Chen S and Wang ZP analyzed the data. Zhang WX and Zhou L contributed analysis tools. Chen S, Li SX, Wang ZP and Zhang WX provided critical inputs on design, analysis, and interpretation of the study. All the authors had access to the data. All authors read and approved the final manuscript as submitted."}
{"text": "There was an error in the original publication . In all The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "Walsh from the London Tubular Centre, UCL Department of Renal Medicine, University College London, London, UK.Consequently, the following was originally omitted from the Acknowledgements: \u2018K.S. is supported by the Wellcome Trust [110282/Z/15/Z]. K.S. and S.B.W. are supported by the UK Space Agency [ST/X000036/1]\u2019.Additionally, the following was originally omitted from the Author Contributions: \u2018T.W., K.T., S.B., K.S., S.W., G.V., A.C., P.B., M.H., J.J. and N.G. critically revised the manuscript. All authors reviewed and approved the final version of the manuscript.\u2019This has been corrected in both the PDF and HTML versions of the article."}
{"text": "In the published article, there was an error regarding the Conflict of Interest for Patrick D. Mahar, Christopher Schuster, Imre Pavo, and Isabella Yali Wang. The Conflict of Interest statement should be:AE has honoraria as consultant and/or speaker from AbbVie, Almirall, Bristol-Meyers Squibb, Leo Pharma, Samsung Bioepis Co., Ltd., Pfizer, Eli Lilly, Novartis, Galderma, and Janssen Pharmaceuticals. LP has received honoraria/consultation fees from Abbvie, Almirall, Amgen, Baxalta, Boehringer Inglheim, Celgene, Gebro, Janssen, Leo-Pharma, Lilly, Merck-Serono, MSD, Mylan, Norvartis, Pfizer, Regeneron, Roche, Sandoz, Samsung-Bioepis, Sanofi and UCB. LP has participated in company sponsored speaker's bureau for Celgene, Janssen, Lilly, MSD, Norvartis and Pfizer. KS is a consultant, investigator, speaker and has received grants from: AbbVie, Amgen, Almirall, Biogen, Bristol-Myers Squibb Boehringer Ingelheim, Celgene, Chugai, Galderma, Janssen-Cilag, Leo-Pharma, Lilly, Merck Sharp & Dohme Corp., Morphosys, Novartis, Pfizer, Regeneron, UCB Pharma. JM is a consultant and/or investigator for Amgen, Bristol-Myers Squibb, Abbvie, Dermavant, Eli Lilly, Novartis, Janssen, UCB, Sanofi-Regeneron, Sun Pharma, Biogen, Pfizer and Leo Pharma. CG has received honoraria or research grants from AbbVie, Almirall, Anaptysbio Boehringer Ingelheim, Bristol Myers Squibb, Eli Lilly and Company, GSK, Janssen, LEO Pharma, Pfizer, Novartis ONO Pharmaceuticals, UCB Pharma and Walgreens Boots Alliance, and is supported in part by the Manchester NIHR Biomedical Research Centre. PM has served as a consultant, investigator, speaker and/or advisor for Novartis, AstraZeneca, Abbvie, Pfizer, Bristol-Meyers Squibb, Eli Lilly and Company and Boehringer Ingelheim. PM, CS, IP, and IW are employees of Eli Lilly and Company. PM owns equity in Eli Lilly and Company. CS, IP, and IW are minor shareholders of Eli Lilly and Company.The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated."}
{"text": "The abovearticle, published online on 6 January 2019 in Wiley Online Library(wileyonlinelibrary.com), has been retracted by agreement between the authorsand John Wiley & Sons Ltd. The retraction has been agreed due to theauthors\u2019 self\u2010reported errors in their data rendering the article\u2019s conclusionsincorrect.Retraction: Nielsen, KL, Hansen, KH, Knudsen, JD, Frimodt\u2010M\u00f8ller,N, Hertz, FB, Jans\u00e5ker, F., In vivo mecillinam resistance in Escherichia coliafter pivmecillinam treatment of a urinary tract infection, MicrobiologyOpen,2019; e770 ( The above article, published onlineon 6 January 2019 in Wiley Online Library (wileyonlinelibrary.com), has been retractedby agreement between the authors and John Wiley & Sons Ltd. The retraction has beenagreed due to the authors\u2019 self\u2010reported errors in their data rendering the article\u2019sconclusions incorrect.Retraction: Nielsen, KL, Hansen, KH, Knudsen, JD, Frimodt\u2010M\u00f8ller, N, Hertz,FB, Jans\u00e5ker, F., In vivo mecillinam resistance in Escherichia coli after pivmecillinamtreatment of a urinary tract infection, MicrobiologyOpen, 2019; e770 ("}
{"text": "Nucleic Acids Research, Volume 33, Issue 18, 1 October 2005, Pages 6000\u20136010, https://doi.org/10.1093/nar/gki897The Editors were alerted in July 2022 about potential issues with Figures 2C and 3B as detailed below.Figure 2C: ISE3wt SRp75 and ISE3wt SRp55 appear to be identical. ISE3m SRp75 and\u00a0+\u00a0SRp75 appear to be identical.Figure 3B: Lanes 5 and 6 appear to be identical.An Expression of Concern was published in February 2023.The experiments were conducted almost 20 years ago, and the authors no longer have the original data.The Editors analysed the two figures and noted areas of similarity in Figure 2C, as well as a likely splice line between the last two lanes of Figure 3B. Some images resulting from the analyses are provided below.The Editors referred the matter to the authors institution for investigation, however the institution referred the matter back to the authors. The authors maintain that they no longer have the original data. The Editors therefore do not have sufficient information to definitively refute the issues identified. While these issues may not affect the results or conclusion of the study, in the absence of original data, the Editors advise readers to examine Figures 2C and 3B with care.Julian E. Sale and Barry L. StoddardSenior Executive Editors"}
{"text": "The authors also apologize to the readership for any inconvenience caused.A revised version of"}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Owing to the fact that the contentious data in Figs. 4 and 5 of the above article had already been published prior to its submission to"}
{"text": "Due to a production error, the consortium French Addictovigilance Network was omitted from the authors list.There has also been an acknowledgments section added that lists the following names, crediting their involvement with the consortium.Alexandra Boucher, Anne Batisse, Anne Roussin, Bernard Fauconneau, C\u00e9cile Chevallier, Fr\u00e9d\u00e9ric Libert, H\u00e9l\u00e8ne Peyri\u00e8re, Jo\u00eblle Micallef, Juliana Tournebize, Maryse Lapeyre-Mestre, Michel Spadari, Nathalie Fouilh\u00e9, Reynald Le Boisselier, Sylvie Deheul, Val\u00e9rie Gibaja.The publisher apologizes for this mistake. The original article has been updated."}
{"text": "Sci. 2022, 9, 2203058Advanced Science, published online on 21 July 2022 in Wiley Online Library (https://onlinelibrary.wiley.com/doi/full/10.1002/advs.202203058), has been retracted by agreement between the authors, the Editor\u2010in\u2010Chief, Kirsten Severing, and Wiley\u2010VCH GmbH. The retraction has been agreed as the article is based on research results and data that the authors were not authorized to use. Moreover, the majority of co\u2010authors have been listed despite insufficient qualification for contributorship.The above article from  Sci. 2022, 9, 2203058Advanced Science, published online on 21 July 2022 in Wiley Online Library (https://onlinelibrary.wiley.com/doi/full/10.1002/advs.202203058), has been retracted by agreement between the authors, the Editor\u2010in\u2010Chief, Kirsten Severing, and Wiley\u2010VCH GmbH. The retraction has been agreed as the article is based on research results and data that the authors were not authorized to use. Moreover, the majority of co\u2010authors have been listed despite insufficient qualification for contributorship.The above article from"}
{"text": "Correction to: Diabetologiahttps://doi.org/10.1007/s00125-022-05729-yIde panel was a duplication of the image used for the control panel. The authors assert that this mistake had no impact on the data analysis, interpretation or conclusions drawn. Figure Unfortunately, in the BrdU staining of alpha-TC1.9 cells shown in Fig."}
{"text": "Following publication, concerns were raised regarding the integrity of the images in the published figures. The authors failed to provide a satisfactory explanation during the investigation, which was conducted in accordance with Frontiers' policies.The retraction was approved by the Chief Editors of Frontiers in Cellular Neuroscience and the Chief Executive of Frontiers. The authors did not agree to the retraction."}
{"text": "The above article, published online on 19 February 2022 in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement between the journal's Editor\u2010in\u2010Chief, Dr Gayle Hallowell, and John Wiley & Sons Ltd. The retraction has been agreed following concerns raised that a number of figures within the results section were not original and had been used without permission from the copyright holder. The authors were asked to provide their original data for review by the editorial team to corroborate their results. The editorial team were unable to verify the data provided and, as a result, have concerns about the conclusions of the article. The journal is therefore issuing this retraction.Beiranvand, S., Piri\u2010Gharaghie, T., Dehganzad, B., Khedmati, F., Jalali, F., AsadAlizadeh, M., & Momtaz, H. (2022). Novel NAD\u2010independent Avibacterium paragallinarum: Isolation, characterization and molecular identification in Iran. Veterinary Medicine and Science, 8, 1157\u2013 1165.  The above article, published online on 19 February 2022 in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement between the journal's Editor\u2010in\u2010Chief, Dr Gayle Hallowell, and John Wiley & Sons Ltd. The retraction has been agreed following concerns raised that a number of figures within the results section were not original and had been used without permission from the copyright holder. The authors were asked to provide their original data for review by the editorial team to corroborate their results. The editorial team were unable to verify the data provided and, as a result, have concerns about the conclusions of the article. The journal is therefore issuing this retraction.Beiranvand, S., Piri\u2010Gharaghie, T., Dehganzad, B., Khedmati, F., Jalali, F., AsadAlizadeh, M., & Momtaz, H. (2022). Novel NAD\u2010independent Avibacterium paragallinarum: Isolation, characterization and molecular identification in Iran. Veterinary Medicine and Science, 8, 1157\u2013 1165."}
{"text": "They also apologize to the readership for any inconvenience caused.The authors were able to re-examine their original data files, and realized that this figure had been inadverently assembled incorrectly. The revised version of"}
{"text": "This erratum corrects the following:4\u00a0QA system in a 0.35 tesla MR linear accelerator. J Appl Clin Med Phys, 22: 82\u201391. https://doi.org/10.1002/acm2.13216 The authors report a change in the conflict of interest statement at the end of the article. The corrected conflict of interest statement is as follows:Desai, V., Bayouth, J., Smilowitz, J. and Yadav, P. (2021), A clinical validation of the MR\u2010compatible Delta\u201cJohn E. Bayouth reports ownership interest in a company that provides consulting services on image guided radiation therapy technology . He/(his employer) received travel reimbursement/speaking fees from ViewRay Inc. The remaining authors have no conflicts of interest to disclose. \u201d"}
{"text": "Retraction Note: Mol Cancer 15, 57 (2016)10.1186/s12943-016-0540-4The Editor-in-Chief has retracted this article at the authors\u2019 request. After publication, concerns were raised regarding multiple cases of H&E staining and western blot image overlap with other articles that were submitted and published within a close time frame \u20138.The authors have stated that the data were mislabelled and the images were misused. The authors and the Editor-in-Chief therefore no longer have confidence in the presented data.Bo Tang has stated on behalf of all co-authors that they agree to this retraction."}
{"text": "BMC Complementary Medicine and Therapies (2013) 13:222.10.1186/1472-6882-13-222The Editor has retracted this article because of concerns with four of the figures, namely:Overlapping images in panels D and E in Fig.\u00a023.Overlapping images in panels A and F in Fig.\u00a025.Images in panels C,D, E and F in Fig.\u00a018 are used in [Images in panels A and C in Fig.\u00a024 and panels A, E and F in Fig.\u00a025 are used in [The Editor therefore no longer has confidence in the results and conclusions presented. Firoz Anwar disagrees with this retraction. Vikas Kumar, Danish Amar, Pushpraj S. Gupta and Mohd Mujeeb have not responded to correspondence from the Editor about this retraction."}
{"text": "Retraction Note: BMC Pharmacology and Toxicology (2022) 23:8610.1186/s40360-022-00625-yThe Editor has retracted this article. After publication, concerns were raised regarding image similarities in Figs.\u00a05 and 8. Specifically:In Fig.\u00a05a and b, images representing groups II and III appear to originate from the same animal;In Fig.\u00a08, all images appear to originate from two samples with slight modifications.The authors have provided the raw data to address these concerns; however, the publisher could not validate the authenticity of these data. The Editor therefore no longer has confidence in the presented data and the conclusions of this article.Zakir Ali, Fatima Zahid, Maimoona Malik and Saba Sohail agree to this retraction. Fakhar ud Din has agreed to this retraction but not to the wording of this retraction notice. Basalat Imran, Salman Khan, Alam Zeb and Gul Majid Khan have not responded to any correspondence from the editor or publisher about this retraction."}
{"text": "RSC Advances is publishing this expression of concern in order to alert our readers that we are presently unable to confirm the reliability of the data presented in the article.The Royal Society of Chemistry became aware of concerns about the reliability of the data presented in Fig. 8 and 12 of the paper.The Royal Society of Chemistry has asked the affiliated institution, Wenzhou Medical University, to investigate this matter and confirm the integrity and reliability of the data in Fig. 8 and 12 of the paper. An expression of concern will continue to be associated with this manuscript until we receive information from the institution on this matter.\u2003Laura Fisher24th August 2023RSC AdvancesExecutive Editor,"}
{"text": "Following publication, concerns were raised regarding the integrity of the images in the published figures. The authors failed to provide the raw data or a satisfactory explanation during the investigation, which was conducted in accordance with Frontiers\u2019 policies. Given the concerns about the validity of the data, and the lack of raw data, the editors no longer have confidence in the findings presented in the article.This retraction was approved by the Chief Editors of Frontiers in Pharmacology and the Chief Executive Editor of Frontiers. The authors agree to this retraction."}
{"text": "The authors wish to make the following corrections to this published paper .In In In The authors apologize for any inconvenience this may have caused and affirm that the scientific conclusions remain unaffected. The original publication has also been updated."}
{"text": "Correction to: Obesity Surgery (2019) 29:3246\u20133251https://doi.org/10.1007/s11695-019-03977-3Due to human error, the authors neglected to multiply the rate by 100 in order to get the percentage; therefore, the published percentage for penetration rate was out by a factor of 100.The correct percentage is included in the paragraph below.This penetration rate of 0.17% is particularly low compared with other published penetration rates, for example, 1.24% in the USA (where the eligible population was defined as adults with BMI\u2009\u2265\u200940) [15] and 0.54% in Canada in 2017 (where the eligible population was defined as adults with BMI\u2009\u2265\u200935) [16]."}
{"text": "The journal retracts the 2021 article cited above.Following publication, concerns were raised regarding the contributions of the authors of the article. Our investigation, conducted in accordance with Frontiers policies, confirmed a serious breach of our authorship policies and of publication ethics; the article is therefore retracted.This retraction was approved by the Chief Editors of Frontiers in Chemistry and the Chief Executive Editor of Frontiers. The authors do not agree to this retraction."}
{"text": "We thank the authors  for elevBecause meat intake is often at the crux of scientific debate on optimal healthy, sustainable diets for the population , this reThe DGA model dietary patterns that are intended to provide examples of healthy dietary patterns use food groups and subgroups rather than individual foods and beverages to avoid being prescriptive . The modWhile the authors  compare"}
{"text": "Rapidly global urbanization and economic growth in the past several decades have resulted in a sharp contraction of arable areas worldwide. However, food supply requirements are quickly increasing due to higher living standards and larger populations. Therefore, food crises are still a major threat to human society. The conflict between farmland areas and the increasing need for essential supplies is becoming acuter in China. Therefore, we suggest that a novel strategy would address the issue, in which temporal and spatial arrangement of wheat sowing dates would be highly focused. Rapidly global urbanization and economic growth in the past several decades have resulted in a sharp contraction of arable areas worldwide. However, food supply requirements are quickly increasing due to higher living standards and larger populations. Therefore, food crises are still a major threat to human society. The conflict between farmland areas and the increasing need for essential supplies is becoming acuter in China because of the large population and the most rapidly increasing living standards . AddressSichuan, as a major grain-producing region in China, has always enjoyed the reputation of being the \u201cHeavenly Land of Plenty\u201d. From 1953 to 1969, Sichuan grain production accounted for 10% of total grain production in China ; howeverOryza sativa L.) and wheat (Triticum aestivum L.) are the primary summer and winter crops of Tianfu Granary and account for approximately 42% and 7% of the total grain production in the region, respectively.Tianfu Granary strategy refers to the crop production region of Sichuan Province, which mainly consists of the Chengdu Plain, Anning Valley and both southern and northeastern parts of Sichuan. This region contains more than 6.7 million hectares, accounting for approximately 5.5% of the arable area of the country . Rice  and ScienceDirect databases, and 8,713 (57.2%) were published after 2010 Table S1In terms of production, wheat usually has a longer growth season than rice, which indicates that the adaptation of wheat to the changes of sowing date could be stronger than that of rice. We further found that the typical wheat sowing date in this region is 1 Nov with a typical range from 25 Oct to 7 Nov, and the average growth duration is approximately 190 d , which would surpass that of the high-yield regions in northern China. Generally, it is a common belief that northern China has a higher wheat unit area yield than southern China due to the length of the growing season. However, according to the described association of yield with sowing date, air temperature and diseases prevalence (Unfortunately, in terms of early-sowing wheat cultivars, few scientists have indeed focused on sowing date except of the association of sowing date and disease epidemics , but of evalence , it is d2 in the lengthened period (Moreover, the increase in yield potential amplitude could also be underestimated because there is more sunshine, precipitation, heat resources and increasing seasonal atmospheric COd period . Early sd period , thus suYr41 to stripe rust and Pm40 to powdery mildew, would largely reduce the risk of diseases (Fhb7 from Thinopyrum elongatum (Surprisingly, in contrast, late sowing has also garnered the attention of various scientists and farmers in the region , leaf rudiseases , and evediseases  and newllongatum  are also3An approach for effectively using cultivars tolerant to early sowing in rice\u2013wheat cropping systems is our last concern. By temporally arranging both dates of wheat sowing and rice harvesting, we precisely established a slight overlapping period with 2 to 5 days between them. Under these conditions, for the spatially optimal arrangement of the wheat sowing date, a new rice\u2013wheat intercross cropping model could further be derived from the traditional rice\u2013wheat cropping system, in which the early drainage of water was the sole essential event ensuring that the farmland successfully changes from wet to dry when rice was harvested. Following this process, we simply planted wheat seeds by unmanned aerial vehicles just one or two days before rice harvesting . Overall42, respectively. Wheat unit area yield could increase by 55.3% by exploiting cultivars tolerant to early sowing so that the corresponding potential of the average and the highest unit area yields of wheat in this region would be as high as 7.9 and 12.1 ton/hm2, respectively. The farmland area for rice growth every year is approximately 1.9 million hectares. Given that 90% of the area is used to grow wheat as part of the rice\u2013wheat intercross cropping model, total wheat production in Tianfu could increase to approximately 12.5 million and even possibly 20.7 million tons, which would significantly overshadow wheat production at present.The total potential wheat production in Tianfu Granary was further estimated according to the above results and was mainly influenced by both the highest unit area yield potential and the total available farmland area in the rice\u2013wheat cropping system for wheat growth. At present, the average and the highest unit area yields of wheat in the Tianfu Granary are 5.1 and 7.8 ton/hmEconomically, cost control is usually the final factor influencing the application prospects of a revolutionarily different system. It is evident that the effect of rice\u2013wheat intercross cropping on cost control is very beneficial. Based on an estimation calculation, each hectare of production would save 2,130 RMB, which is the sum of 1300, 300, 450 and 180 RMB saved from the absence of plowing, simplified sowing procedure, decrease in fertilizer utilization and removal of herbicides from production, respectively. Similarly, if 90% of farmland for rice cultivation is used to grow wheat with the rice\u2013wheat intercross cropping model, a total of 3.6 billion RMB would be saved. In addition, early sowing of wheat also decreases the carbon emission peak and shortens the time needed to achieve carbon neutrality as photosynthesis occurs for a longer duration during which carbon dioxide is effectively assimilated.Conclusively, it is a biologically ideal choice to adjust the wheat sowing date due to its strong tolerance, and using wheat cultivars tolerant to early sowing in the rice\u2013wheat intercross cropping system is a promising application of this system; thus, these two approaches would have a significant effect on total wheat production in Tianfu Granary, accompanied by considerable economic savings and an ecological contribution to the carbon economy. Thus, optimizing the temporal and spatial arrangement of wheat sowing dates by developing and applying wheat cultivars highly tolerant to early sowing would be a revolutionary strategy to develop for the Tianfu Granary in the future.The original contributions presented in the study are included in the article/PL and FT conceived the idea, wrote the manuscript. YH, XH, JJ and HY collected the data and analyzed the data. YH participated in the review & editing of the manuscript. All authors contributed to the article and approved the submitted version."}
{"text": "Mater. Chem. A, 2023, https://doi.org/10.1039/D2TA07686A.Correction for \u2018The role of ion solvation in lithium mediated nitrogen reduction\u2019 by O. Westhead  The corrected yield rate is 0.53 \u00b1 0.04 nmol cm\u22122 s\u22121 (n = 3) and the corrected version of The authors regret an error in their calculation of the yield rate in An independent expert reviewed the data provided by the authors and concluded that it does not change the discussion or conclusions presented in the article.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "In Ding Ma et al,The authors confirm all results and conclusions of this article remain unchanged. The authors wish to apologize for any misunderstanding or inconvenience caused."}
{"text": "This article has been corrected at the request of the authors to edit data that had typographical errors in the initial published version:In Table 6, column 3, rows 3-6 have been updated from:0.930.970.750.65To:\u00a00.290.191.751.65The corresponding data in the abstract has also been updated accordingly. The authors deeply regret that these errors were not identified and addressed prior to publication."}
{"text": "This article has been retracted: Aging has completed its investigation of this paper after communicating with the authors. We received a letter from the authors stating that, \u201cit was found in our subsequent studies that the AMPK pathway in lens epithelial cells was not activated after H202 intervention. In order to better investigate the mechanism of oxidative stress in lens epithelial cells and explore new signaling pathways, we plan to withdraw/retract the manuscript and redesign the research.\u201d All authors agreed with this decision and signed the letter."}
{"text": "Biol. Open (2018) 7, bio036194 (doi:10.1242/bio.036194).There were errors published in In Fig.\u00a02, the SiTAZ images in panel A were erroneously a duplication of the SiIRS-1 images. In addition, the control (non-transfected) panels were repeated in Fig.\u00a02A and Fig.\u00a04A. The corrected Fig.\u00a02 is shown below.Also, Fig\u00a05J contained an incorrect image for the \u2018IRS-1 over-expressed\u2019 panel. The corrected Fig.\u00a05 is shown below.The authors apologise to readers for these errors, which do not impact the results or conclusions of this paper."}
{"text": "In the original publication , there w1,\u2020, Piergiorgio Capaci 1,\u2020, Fabrizio Barozzi 1,\u2020, Danilo Migoni 1, Makarena Rojas 1, Egidio Stigliano 2, Francesco Paolo Fanizzi 1, Gian Pietro Di Sansebastiano 1,*, Paride Papadia 1,*.Chiara Anglana A correction has been made to the Author Contributions (Page 11):Author Contributions: C.A., P.C., F.B., P.P. and G.P.D.S.: equally contributed to the study design and implementation. Material preparation and data collection were performed by C.A., P.C., F.B., M.R. and F.P.F. provided the reagents and the facilities used for all the chemical analysis. Chemical analysis were performed by F.B. and D.M. The first draft of the manuscript was written by P.P. and G.P.D.S. The manuscript was critically reviewed by F.P.F., C.A., P.C., F.B., and E.S. All authors have read and agreed to the published version of the manuscript.The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "Biomaterials Research (2022) 26:6210.1186/s40824-022-00304-3The authors of the original article [1] mistakenly omitted co-first authorship attribution between the first two authors: Gyeongwoo Lee and Young-Gwang Ko. Both authors should be considered co-first authors."}
{"text": "To the Editor,We read the article by Isono et al.As clarified, neck pain exacerbated by rotation or pressure, accompanied by fever and an elevated inflammatory response on blood tests strongly suggests CDS. However, this clinical picture may mimic acute meningitis with head/neck pain with jolt accentuation especially when accompanied by fever.The authors declare no conflict of interest regarding this submission."}
{"text": "Epub 2023 Jan 11. PMID: 36582172; PMCID: PMC10067410.][Luo H, Wang L, Zhang D, Sun Y, Wang S, Song S, Ge H. HA15 inhibits binding immunoglobulin protein and enhances the efficacy of radiation therapy in esophageal squamous cell carcinoma. Cancer Sci. 2023 Apr;114(4):1697\u20131709. doi: The authors found that it was not rigorous enough to use HSP90 as loading control for Figure\u00a0The corrected Figures\u00a0We apologize for this error."}
{"text": "Fig. 2a: The representative ALP staining images of 15 and 30\u00a0\u03bcM are both chosen from the 30\u00a0\u03bcM groupFigs. 4d, 5h and 5i: The same \u03b2-actin blot is used.Fig. 4e and f: The same \u03b2-actin blot is usedFig. 5a: The representative ALP staining images of Azo+si-glp-1r-1 and Azo+si-glp-1r-2 are the sameThe Editors-in-Chief have retracted this article\u00a0at the authors' request. After publication, the authors\u00a0found errors in the\u00a0following figure panels:The authors provided the raw data for validation. However, further checks by the Publisher identified some differences between the raw data and the figures, as well as high similarity between the original gel images for Fig.\u00a05b GLP-1 and 5i Fabp4. The Editors-in-Chief\u00a0and the authors\u00a0therefore no longer have confidence in the presented data.All authors agree to this retraction."}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Owing to the fact that the contentious data in the above article had already been published prior to its submission to"}
{"text": "The journal retracts the 29 November 2021 article cited above.Following publication, concerns were raised regarding data misrepresentation. Specifically, patterns of repeated signals were identified in Figures 4B, 4C and 7. The authors failed to provide a satisfactory explanation during the investigation, which was conducted in accordance with Frontiers\u2019 policies. As a result, the data and conclusions of the article have been deemed unreliable and the article has been retracted.This retraction was approved by the Chief Editors of Frontiers in Chemistry and the Chief Executive Editor of Frontiers. The authors do not agree to this retraction."}
{"text": "The journal retracts the 28 May 2021 article cited above.Following publication, concerns were raised regarding the integrity of the images in the published figures. Upon further assessment, Image duplication was identified in Figures 2F and 3I and Figures 2B and 3C.The authors were responsive to our queries during the investigation, which was conducted in accordance with Frontiers' policies. However, they were unable to provide a satisfactory explanation during the investigation that allowed us to verify the data and conclusions presented. As a result, the data and conclusions of the article have been deemed unreliable and the article has been retracted.This retraction was approved by the Chief Editor of Frontiers in Molecular Neuroscience and the Chief Executive Editor of Frontiers. The authors did not agree to this retraction."}
{"text": "The bark fulfils several essential functions in vascular plants and yields a wealth of raw materials, but the understanding of bark structure and function strongly lags behind our knowledge with respect to other plant tissues. The recent technological advances in sampling and preparation of barks for anatomical studies, along with the establishment of an agreed bark terminology, paved the way for more bark anatomical research. Whilst datasets reveal bark\u2019s taxonomic and functional diversity in various ecosystems, a better understanding of the bark can advance the understanding of plants\u2019 physiological and environmental challenges and solutions. We propose a set of priorities for understanding and further developing bark anatomical studies, including periderm structure in woody plants, phloem phenology, methods in bark anatomy research, bark functional ecology, relationships between bark macroscopic appearance, and its microscopic structure and discuss how to achieve these ambitious goals. The bark , can be divided into inner and outer bark according to their developmental origin and status . The corQuercus suber (cork oak), the major model plant for cork structure, chemistry, and development, suberin accounts for about 40% of the phellem cell wall components, lignin being the second most abundant constituent (~25%) . Int (~25%) , while i% lignin . Cork ce. Int  and Cordia (Boraginaceae) )Bark has many defensive functions, and not surprisingly, its development is also influenced not only by ethylene ,20, but While plant hormones are the upstream regulators of bark formation and cell differentiation, they do not do it directly, but via changing the expression and activity of a very long list of genes including regulatory ones. Though a good coverage of this issue is outside the scope of this review; we give below a few references to this subject ,32,33.The tremendous diversity of bark macrostructure and its anatomical background still needs to be explored. The relations between macro- and microstructure of bark have been considered by few authors ,38,39,40To a large extent, external bark appearance is determined by two functional features: (1) by the ability or disability of the outermost layers of bark to maintain its continuity in the course of tangential expansion , and (2) by the presence or absence of separation layers, i.e., the layers of fragile tissues enabling a regular abscission of outer portions of bark. Diverse barks can be classified into four major architectural types: stretched, exfoliating, furrowed and peeling barks , and comAdansonia za, Platanus sp., sensu [Stretched , however, these functions are allocated differently: the periderm is responsible for protection, while the nonconducting phloem\u2014for the separation of abscised portions [Unlike the barks of these two types, the furrowed  the formation of new phloem cells by the cambium (positive contribution) and (b) the collapse of older phloem cells (negative contribution). Seasonal differences in width and structure of the conducting phloem indicate that the progression of these two processes is not synchronized [The width of the conducting phloem is species-specific, being on average 30% and 55% wider in hronized . While thronized ,58, the hronized .The above examples illustrate the need to consider the timing of sampling to ensure reliable data interpretation when comparing results from different laboratories on an intra-annual time scale . Hence, Although our understanding of the functional ecology of bark is still limited, especially in comparison with wood, it has significantly improved in the last decade. One of the main reasons for this has been a shift from studies aiming to explain the remarkably high variation in bark traits based solely on protection against fire, to studies that recognize that bark is shaped by diverse functions ,61,62. CIn general, we know very little about the function of bark colors. There are many tree species with brownish or grayish barks, but there are many other species in which the bark is conspicuously colorful A. It canAlthough significant progress has been made in understanding how different functions play out in bark\u2019s structural diversity, we are still far from fully understanding bark\u2019s structure-function relationships. This is for sure one of the most promising venues for future research in bark functional ecology. For example, it is unclear which are the tissues or main regions that drive variation in bark density or bark storage capacity. A bark with high density tends to be thinner, has lower storage capacity, and also lower decomposition rates ,78. MoreThe main reason repeatedly reported for why barks are much less studied than all others plant tissues and organs is the methodological limitation ,17. BarkThe first step is always fixing the collected bark samples in liquid. Fixatives such as paraformaldehyde or FAA  can be The study of bark anatomy requires a staining method that singles out lignified from non-lignified tissues. This is fundamental to aid in the correct identification of the different cell types that compose the bark, and to understand bark development and function . Barks with a lot of fibers, for instance, almost entirely lack sieve tube collapse, even in their non-conducting parts . Double-https://qwa-net.com/(accessed on 30 April 2023)) symposium on bark structure that the authors of this article organized and participated in. We realized that there is a lot of interest in this topic in the scientific community, while at the same time there is a general lack of knowledge and methodological know-how. This article tries to provide an overview of bark structural and functional anatomy, as well as to propose venues for future research. Many open questions yet remain; some were discussed throughout the article, and several are mentioned below.Bark structure is scarcely studied compared to wood or leaf anatomy. However, this is a broad topic with many unanswered questions and a crucial one to understand the remarkably wide variation in bark morphology and function. The idea for this article arrived after a Q-net (Quantitative Wood Anatomy Network, External appearance of bark depends largely on its ability or disability to maintain its continuity in the course of tangential expansion, and the presence or absence of separation layers enabling a regular abscission of its outer portions. Four major types of bark architecture can be distinguished on this basis. Anatomical background of bark stretching without superficial disruption as well as the allocation of protective and separation layers within outer bark in different plant groups are, however, still poorly known.Similarly, the ecological significance of bark features such as color, photosynthetic function, density, and more is poorly understood. Moreover, the link between bark structure and environmental stresses is yet mostly unexplored.Bark biomechanics is a largely unexplored topic. Is dilatation induced by mechanic tension or is it only a hormonal response? This topic merits an interdisciplinary study with precise measurements.Phloem research lags behind xylem largely because of technical issues. How does the phloem structure\u2013function relationship change under stress? In order to answer this question, sampling methodology must be clarified.We hope that this short review will stimulate interest in bark research and encourage new collaborations and studies of this important and largely ignored topic."}
{"text": "This is a peer-review report submitted for the paper \u201cImpact of Modifiable Risk Factors on the Occurrence of Cutaneous Leishmaniasis in Diyala, Iraq: Case-Control Study.\u201dThis paper  is suitaAlthough this paper has a large sample size, it is not clear how the sample size is calculated.There is no major comment.This paper needs some minor revisions.1. Results section: the word \u201cpersons\u201d in the sentence \u201cData from 844 persons  persons were analyzed.\u201d is repeated. Therefore, it should be deleted.2. Results section: I suggest the authors include quantitative results in the Abstract .Conclusion section.3. I suggest the authors merge the Recommendations under the 4. The authors explained the abbreviation (CL) for cutaneous leishmaniasis at the beginning of the introduction but sometimes did not use it in the main text.Methods section of this manuscript. Also, delete reference 17.5. \u201cFurther details on why we selected these two districts and how the study was conducted were published elsewhere.\u201d The authors should delete this sentence and explain why the two districts were selected and how the study was conducted in the 6. \u201cA total of 866 persons were interviewed within the 717 families visited, 451 cases (292 from Al-Mansuriya District and 159 from Al-Muqdadiya District) and 415 controls (182 Al-Mansuriya District and 233 from Al-Muqdadiya District). However, we excluded 22 persons from the sample due to incomplete information. The final sample size used was 844 persons .\u201d Although the sample size is large, there is no statistical method to estimate the sample size.7. \u201cData from 844 persons  persons were analyzed.\u201d As mentioned before, the authors must delete the repeated word \u201cpersons.\u201d8. The authors must mention the table in the correct position in the text.9. Table 1: the number of cases and controls for the \u201cuse bed net\u201d and \u201csleeping habits\u201d variables aren\u2019t similar to the sample size. The authors need to review the numbers and calculate the percentages. Moreover, the authors must explain the total number of cases and controls for the variable \u201cdistance of animals from house\u201d in a footnote of instead in the table.10. Table 2: the attributable fraction for fogging is wrong (10.2 and 28.2). Please change it; the correct fraction is (52.6 and 55.5).11. The authors need more references to compare these findings with previous literature reports."}
{"text": "Following the publication of this article , concernThe corresponding author stated that the original data underlying the published results are no longer available. In absence of these data, the concern with Fig 2 cannot be resolved and the Fig 2 results should be interpreted with caution.PLOS ONE Editors issue this Expression of Concern to notify readers of the above concerns.In light of this the"}
{"text": "Frontiers Educational Psychology published in March 2022 regarding the results of a 2 \u00d7 2 factorial design with 10 subjects per cell  a total of 77 subjects. Since in the context of educational psychology, a large size effect is very unlikely, this study with 40 subjects is more than \u201csomewhat underpowered\u201d (p. 6). The authors resolve the problem by doing frequentist and Bayesian inference, which means that they double the number of statistical tests performed. This is not really the solution because the global type I error increases drastically.Please do not misunderstand the purpose of this commentary: it is not meant as a reproach to the authors but as a reflection on solutions.Frontiers and other psychological reviews. There should be a rethinking of how instructors teach this aspect in higher education, i.e. move more on conceptual issues and consequences than on technicalities. Focusing on real data, Spiegelhalter (It seems that the teaching of statistics and methodology in the cursus of psychology is insufficiently focused on sample size issues because this problem still arises in elhalter  perfectlThen, it is the duty of a scientific journal's editors in chief to apply a minimum of statistical reviewing because they act as gatekeepers of scientific quality. First, they could edit guidelines for statistical reporting to help authors improve it. The American Psychological Association  manual iThe author confirms being the sole contributor of this work and has approved it for publication."}
{"text": "In the original publication , there wIn the original publication , there wThe authors would like to apologize for any inconvenience to the readers caused by these errors. The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "Takada Yumemi, Shinji Yoshii. DEN Open. 2022 May 13;3(1)In author name, \u201cTakada Yumemi\u201d was incorrect. This should have read: \u201cYumemi Takada\u201d.We apologize for this error."}
{"text": "The above abstract [1] published with Wai-Leung Ng\u2019s name spelled incorrectly.It also published without the middle initials for Lark J. Perez and Matthew B. Neiditch or the proper affiliations.The correct list of authors and their affiliations is as follows:1, Wai-Leung Ng2, Anjali Steenhaut2, Sandra Olenic2, Lark J. Perez3, Matthew B. Neiditch1Andrew Guarnaccia1Department of Microbiology, Biochemistry, and Molecular Genetics, New Jersey Medical School, Rutgers, 2Department of Molecular Biology and Microbiology, Tufts University School of Medicine, 3Department of Chemistry & Biochemistry, Rowan UniversityThe original abstract has been corrected online to rectify these errors."}
{"text": "Viviana A. Cavieres and Gonzalo A. Mardones were not included as authors in the original publication . Due to Fernando M. Ruggiero: conceptualization, methodology, data curation, formal analysis, writing\u2014original draft, writing\u2014review and editing, supervision, project administration, and investigation. Natalia Mart\u00ednez-Koteski: methodology, data curation, formal analysis, writing\u2014review and editing, and investigation. Viviana A. Cavieres: methodology and validation. Gonzalo A. Mardones: conceptualization, funding acquisition, project administration, resources, and supervision. Gerardo D. Fidelio: resources, writing\u2014review and editing, and project administration. Aldo A. Vilcaes: conceptualization, methodology, resources, data curation, formal analysis, writing\u2014review and editing, supervision, project administration, and investigation. Jose L. Daniotti: conceptualization, resources, supervision, and funding acquisition."}
{"text": "Nature Genetics 10.1038/s41588-023-01335-9. Published online 13 March 2023.Correction to: Hepatology70, 1360\u20131376 (2019)) was cited in error and has now been removed. In the third sentence of the Results subsection \u201cWNT/\u03b2-catenin signaling promotes TLPC-to-hepatocyte conversion,\u201d now reading in part \u201cConsidering the higher expression of WNT/\u03b2-catenin-regulated genes \u2026 and the role of WNT/\u03b2-catenin signaling in promoting hepatocyte fate,\u201d a citation after \u201chepatocyte fate\u201d has been changed from Sekiya, 2011 ) to Boulter, 2012 ). In the last paragraph of the Discussion, the second sentence now includes three new citations ; Cordero-Espinoza, Cell Stem Cell28, 1907\u20131921 (2021); and J\u00f6rs, J. Clin. Invest. 125, 2445\u20132457 (2015)), and the end of the fourth sentence has been amended to include a citation to Boulter, 2012. The changes are reflected in the HTML and PDF versions of the article.In the version of this article originally published, reference errors that arose during revisions have now been corrected as follows. In the first sentence of the Results subsection \u201cBipotent TLPCs differentiate into hepatocytes or BECs,\u201d Thakur, 2019 ("}
{"text": "This is the authors\u2019 response to peer-review reports for \u201cInformation Technology Ambidexterity, Digital Dynamic Capability, and Knowledge Processes as Enablers of Patient Agility: Empirical Study\u201dComments and Responses by the Authors MethodsDescribe the study [Move the highlighted (in the reviewed manuscript) content under Data Collection Procedures to a new subsection under subsection heading Study Population (see comments in the reviewed manuscript)The highlighted content should be under a new subsection heading Study DesignProvide content on another two subsection headings:Sampling TechniquesSample SizeSeparate content under Data Collection Procedure into two new subsection headingsData Collection Tool and ProcedureData Analysis and ManagementMove Table 1 to Analyses & Results sectionProvide content under two new subsection headings: Inclusion and Exclusion CriteriaEthics ConsiderationsAuthors: The sections mentioned in this review  are esseInclusion and exclusion criteria were combined with sample size, as we described how we got the final sample and why we included respondents (and why not).AbstractDo not begin a sentence with abbreviation of figureUse past tense under Methods See comments in the reviewed manuscriptIntroductionUse physicians in lieu of doctorsUse health care providers not other medical professionalsKeep in-text citation to the end of sentenceAdd health information management professionals among the key stakeholdersConsider reducing the whole of section 2  to 1-2 paragraphs and keep it within the Introduction section just before your study objective. This is to reduce readers\u2019 boredom.Compress the content under research models and hypothesesResultsMake your findings more visible hereMake your writing more readable to known and unknown readersDiscussionPlausible and insightful discussion but not a reflection of the content under the Results. Make the Results section more readable and meaningful to your audience.FigureUse Fig not FigureAcknowledgement It is scientifically necessary that you acknowledge the numerous (n=107) participants, who are the major stakeholders in your research.ReferenceList at least 3 authors before et al Follow the Referencing Style consistentlyOthersUse participants not respondentsAuthors: We adjusted this accordingly.Thank you for the opportunity to review this paper on the lesser known topic of information and communications technology ambidexterity. The paper is well cited, uses appropriate methods, and discusses the concepts and findings in a clear and thorough manner. The paper should appeal to a broad audience. It is a good example of the underrepresented information and communications technology\u2013centered literature in health care.Authors: We would like to thank this reviewer for these kind words . We hopeWell thought out study design with specific hypotheses and methods of analysis spelled out. Interesting conclusions drawn out that would be fruitful for further discussion and analysis to replicate on a broader sample of hospital systems outside of the current reviewed sites.Authors: We would also like to thank this reviewer for these kind words . We agre"}
{"text": "This correction does not impact the conclusions of the original paper. The affected NT50 values of the two mAbs only differed <2 fold. The authors regret the inconvenience caused by this error, which has been corrected in the original article online.In Figure\u00a06A, the authors discovered after publication that the neutralization NT"}
{"text": "This is a peer review submitted for the paper \u201cA Framework for a Statistical Characterization of Epidemic Cycles: COVID-19 Case Study.\u201dIt seems that the aim of this submission  is to reThe aim of the study should be stated in a precise statement with supportive ways to test the underlying hypothesis;Details of the analytical approach should be given with its assumptions and limitations;Sources of the data with overall reliability can be detailed;Use the appropriate and conventional terms of infectious diseases by checking the contents of the submission with reliable epidemiologists.I am satisfied with the modifications to the new version. Almost all of my concerns were addressed in the new version. I will let the readers decide about the validity of the model since the authors elaborated on the approach."}
{"text": "Retraction Note: Cancer Cell Int (2019) 19:5810.1186/s12935-019-0777-2The Editors-in-Chief have retracted this article. After publication, concerns were raised regarding the data in several figures. Specifically:Figure\u00a02a has very unusual shapes for flow cytometry plots.The mito-LC3 western blot in Fig.\u00a04f appears highly similar to Fig.\u00a03e CIII-core2 in , which wThere appears to be a vertical break in the p62 western blot background in Fig.\u00a04f.The authors have stated that these experiments were outsourced to a third party, and the raw data are no longer available. The Editors-in-Chief therefore no longer have confidence in the presented data.All authors agree to this retraction."}
{"text": "The authors wish to make the following change to their paper . Figure \u00a0to:\u00a0The authors would like to apologize for any inconvenience caused to the readers by these changes. The changes do not affect the scientific results. The original publication has also been updated."}
{"text": "Aging Cell. 2021 Oct;20(10):e13471. 10.1111/acel.13471.Rocchi, A., Carminati, E., De Fusco, A., Kowalska, J.A., Floss, T., Benfenati, F. REST/NRSF deficiency impairs autophagy and leads to cellular senescence in neurons. In the published version of the above article, the authors noticed that one of the funding grants from the Italian Ministry of Health was mistakenly omitted. The last sentence in the Acknowledgment section should read as follows:GR\u20102019\u201012370176 to AR)\u2019.\u2018This work was supported by Ministero Istruzione, Universit\u00e0 e Ricerca (PRIN\u20102017A9MK4R to FB), Compagnia di San Paolo Torino (n. 34760 to FB), and Ministero della Salute Ricerca Finalizzata (GR\u20102016\u201002363972 and The authors apologize for the error."}
{"text": "Background and Objectives: Chronic rhinosinusitis with nasal polyps (CRSwNP) presently remains a difficult disease to manage. Antimicrobial and defense proteins are important factors that could help characterize the role of microorganisms in CRSwNP pathogenesis, as the concept of microbial dysbiosis in CRS is still being considered. Our aim is to investigate the complex appearance, relative distribution and interlinks of human \u03b2 defensin 2 (HBD-2), human \u03b2 defensin 3 (HBD-3), human \u03b2 defensin 4 (HBD-4), and cathelicidin LL 37 (LL 37) in chronic rhinosinusitis with nasal polyps (CRSwNP)-affected human nasal mucosa. Materials and Methods: The study group consisted of 48 samples from patients with CRSwNP. Samples were collected during functional endoscopic sinus surgery. The control group consisted of 17 normal healthy nasal mucosa samples gathered during routine septoplasty. \u03b2-defensin-2, \u03b2-defensin-3, \u03b2-defensin-4 and cathelicidin LL 37 in tissue were detected via immunohistochemical analysis. Results: HBD-2, HBD-3 and LL 37 were significantly decreased in epithelial cells in both primary and recurrent nasal polyp samples (p < 0.001) in comparison to control samples. HBD-2 was decreased in the subepithelial connective tissue of primary nasal polyp samples when compared to both recurrent polyp (p = 0.050) and control (p = 0.033) samples. In subepithelial connective tissue, significantly more HBD-3-positive structures were observed in primary nasal polyp samples (p = 0.049) than in control samples. In primary polyp samples, moderate correlations between connective tissue HBD-3 and connective  and epithelial tissue LL 37  were observed. Conclusions: Decreased HBD-2, HBD-3 and LL 37 concentrations in the epithelium suggest a dysfunction of the epithelial barrier in patients with nasal polyps. Decreased subepithelial connective tissue HBD-2 suggests different responses to nasal microbiota in patients with primary nasal polyps compared to recurrent nasal polyps. Increased HBD-3 in subepithelial connective tissue suggests a possible role of this antimicrobial peptide in the pathogenesis of primary nasal polyps. Chronic rhinosinusitis (CRS) is described as an inflammation of the nasal cavity and paranasal sinuses, with symptoms such as nasal congestion, nasal discharge, and hyposmia/anosmia as well as facial pressure/pain. In the case of CRS, symptoms persist for longer than 12 weeks and cause a significant decrease in quality of life . The preThe involvement of bacterial pathogens in the pathogenesis of CRS has been considered. Alteration in the local composition of microorganisms in a sinonasal setting accompanied by disturbance of mucosa is behind the so-called dysbiosis theory . AlthougDefensins are cationic peptides containing 4\u20135 disulphide bridges with a size of 45 to 54 amino acids . The defHuman beta defensin 2 (HBD-2) is secreted by epithelial cells when encountering microorganisms or by activation of pro-inflammatory cytokines. Pro-inflammatory cytokines or pathogen-associated molecular patterns can activate various signaling pathways via toll-like receptors 2 and 4. Along with antimicrobial activity, HBD-2 can also stimulate toll-like receptor expression on the surface of immune cells as well as their chemotaxis. HBD-2 has an important defensive role in the oral cavity. Gingival tissue has demonstrated continuous secretion of HBD-2 in the absence of inflammation, but oral keratinocytes produce it only when stimulated by proinflammatory cytokines in response to bacterial exotoxins . HBD-2 hStaphylococcus antibiotic-resistant strains [Staphylococcus aureus has been shown to be capable of adapting its phenotype to become resistant to both HBD-2 and HBD-3 in cystic fibrosis patients [Pseudomonas aeruginosa, Acinetobacter baumannii and Stenotrophomonas maltophilia with bactericidal action within 1\u20135 min. HBD-3 shows slower activity against Gram-positive species, from 10 to 20 min. Salt resistance has been observed in HBD-3, giving it strong antibacterial activity and the ability to retain physiological salt concentrations [Human beta defensin 3 (HBD-3) also exhibits antimicrobial activity as well as adaptive immune reactions such as chemotaxis. HBD-3 has shown broad spectrum activity against several drug-resistant bacteria . This pe strains . HBD-3-c strains . Howeverpatients . HBD-3 htrations .P. aeruginosa and S. pneumoniae. HBD-3 and HBD-4 have both demonstrated the ability to activate mast cells and increase vascular permeability [P. aeruginosa out of all human beta defensins [Human beta defensin 4 (HBD-4) has been observed in the testis, uterus, kidneys, and gastric mucosa. HBD-4 expression is also seen in human respiratory mucosa in response to eability . HBD-4 pefensins . HBD-3 aefensins .Cathelicidin LL 37 (LL 37) is a mature form of human cathelicidin. It is named after its possibility to inhibit the protease cathepsin-L. LL 37 serves as a primary defense against bacteria and other pathogens during inflammation. Cathelicidins can destroy biofilms, viruses, parasites, and fungi and modulate as well as stimulate cells of the innate and adaptive immune systems. LL 37 is expressed in various tissues such as the intestinal epithelium, respiratory system, and genitals. Cathelicidins can also play a role in angiogenesis, wound healing and apoptosis regulation . LL 37 hThe previously described antimicrobial proteins possess activity against microorganisms found in the nasal cavity and paranasal sinuses; therefore, our aim is to investigate the complex appearance, relative distribution and interlinks of human \u03b2 defensin 2 (HBD-2), human \u03b2 defensin 3 (HBD-3), human \u03b2 defensin 4 (HBD-4), and cathelicidin LL 37 (LL 37) in chronic rhinosinusitis with nasal polyps (CRSwNP)-affected human nasal mucosa.A total of 48 patients with previous diagnosis of CRSwNP and no known immunodeficiencies or coagulopathies were included in the study group. Patients with CRS exacerbation less than two weeks prior to surgery were excluded. Nasal polyp samples were taken during functional endoscopic sinus surgery (FESS). The study group was further divided into 29 patients undergoing their first surgery , 29 to 78 years old, with an average age of 48 years and 19 patients experiencing a recurrence of nasal polyps after previous surgeries , 31 to 88 years old, with an average age of 56 years. The control group consisted of 17 otherwise healthy individuals, with an age range from 29 to 74 years and an average of 39 years, with isolated nasal septum deviation and no known diagnosis of CRS or any other sinonasal pathologies. Control group patients had no history of nasal surgery. Patients with immunodeficiencies and coagulopathies were excluded from the study group. Mucosa samples were taken from mucosa of inferior nasal turbinates. The nature of the study was explained, and written consent was obtained from each participant. The study was carried out with the approval of the local ethics committee of Riga Stradins University (6-1/10/59. 26 October 2020).2\u00b72H2O, MgCl2\u00b76H2O, NaHCO3, NaH2PO4\u00b7H2O, and glucose) containing 10% saccharose for 12 h and then embedded into paraffin. Three-micrometre-thin sections were cut and biotin\u2013streptavidin immunohistochemical staining was used to detect HBD-2 ; HBD-4 ; HBD-3 ; LL 37 .Samples were collected and placed in a mixture of 2% formaldehyde and 0.2% picric acid in 0.1 M phosphate buffer, with a pH of 7.2, for up to 72 h; afterwards, they were rinsed in Tyrode\u2019s buffer  . It is ap < 0.001) and recurrent nasal polyp samples (p < 0.001) when compared to controls. HBD-2 was decreased in the subepithelial connective tissue of primary nasal polyp samples when compared to both recurrent polyp (p = 0.050) and control (p = 0.026) samples. In addition, HBD-3 was observed to be significantly decreased in the epithelia of both primary (p < 0.001) and recurrent (p < 0.001) nasal polyp samples in comparison to the epithelial cells of control samples. In subepithelial connective tissue, significantly more HBD-3-positive structures were observed in primary nasal polyp samples (p = 0.049) than in control samples. Significantly decreased LL 37 was seen in both primary (p < 0.001) and recurrent nasal polyp samples (p < 0.001) after comparison with the control group  was observed in the epithelia of both primary and recurrent nasal polyp samples, but in subepithelial connective tissue, primary polyp samples mainly showed few positive structures (+) while recurrent polyp samples had a few to moderate (+/++) number of positive structures a. ControHBD-3 showed occasional positive structures (0/+) in both primary and recurrent nasal polyp epithelia, and both showed few to moderate positive structures (+/++) in subepithelial connective tissue c. ControHBD-4-positive structures were not detected in nasal polyp tissue a nor in Correlations between factors in primary and recurrent nasal polyp samples were evaluated using Spearman\u2019s rank correlation. Values of coefficients: \u22650.81\u2014a very strong correlation, 0.61\u20130.80\u2014a strong correlation, 0.41\u20130.60\u2014moderate correlation, 0.21\u20130.40\u2014weak correlation, 0.01\u20130.20\u2014no correlation between two factors.p < 0.001). Moderate correlations were seen between connective tissue LL 37 and connective tissue HBD-3 , connective tissue HBD-2 and epithelial HBD-2  and epithelial LL 37 and connective tissue HBD-3   .p = 0.004) and a moderate correlation between epithelial HBD-2 and epithelial HBD-3  were found  is a protein-based detection method whereas a real-time polymerase chain reaction (PCR) is a deoxyribonucleic acid (DNA)-based detection method . TherefoThis study possesses various limitations. When describing HBD-2 and HBD-3 in the context of Gram-positive and Gram-negative bacteria, bacterial cultures and analysis of the microbiome and microbiota should be performed. Analysis with ELISA would be beneficial in evaluating antimicrobial peptide concentration. Additional data, such as use of medications and known comorbidities, would be beneficial in future studies.Decreased HBD-2, HBD-3 and LL 37 concentrations in the epithelium suggest a dysfunction of the epithelial barrier in patients with nasal polyps. Decreased subepithelial connective tissue HBD-2 suggests different responses to nasal microbiota in patients with primary nasal polyps compared to recurrent nasal polyps. Increased HBD-3 in subepithelial connective tissue suggests a possible role of this antimicrobial peptide in the pathogenesis of primary nasal polyps."}
{"text": "Retraction Note: BMC Complement Med Ther 16, 459 (2016)10.1186/s12906-016-1390-8The Editor has retracted this article because of significant concerns regarding Figs.\u00a02 and 4\u00a0A presented in this work, which question the integrity of the data. Further investigation found substantial text overlap with two other publications by the same authors , 2. The"}
{"text": "J Occup Health. Jan 2023;65(1):e12385. doi:In Table\u00a0We apologize for this error."}
{"text": "Diadema setosum) shells reinforced with polyvinyl alcohol for alveolar bone tissue engineering\u2019 by Muhammad Amir Jamilludin et al., RSC Adv., 2023, 13, 32444\u201332456, https://doi.org/10.1039/D3RA06165E.Correction for \u2018Functionalized cellulose nanofibrils in carbonate-substituted hydroxyapatite nanorod-based scaffold from long-spined sea urchin ( The authors regret that the C-HAp degree of crystallinity is incorrectly presented in The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Clin Lab: 67, 2021. The Editorial Office conducted an independent investigation of this matter, and were able to substantiate the reader's claims; moreover, a paper submitted to and accepted in the journal Kaohsiung J Med Sci over a similar time period, which did feature some of the same authors as the abovementioned Oncol Lett paper, likewise contained several of the same data.Oncology Letters has decided that this paper should be retracted from the journal. he authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Owing to the fact that a large number of data in this paper had also been published in two other articles that were accepted at approximately the same time, the Editor of"}
{"text": "LP299Vlication . A correThe authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "In Qiong Qin et al.In figure 1, the images on labels e and f were duplicated. The images on label e must be deleted. The authors apologize for the error and any inconvenience it may have caused."}
{"text": "Due to a production error, the authors \u201cChangyan Ju\u201d and \u201cYanping Ma\u201d sharing first authorship was not indicated clearly with the \u201cdagger mark\u201d.The correct statement to follow is \u201cThese authors share first authorship\u201d.The publisher apologizes for this mistake. The original article has been updated."}
{"text": "In \u201cThe Association of a Geographically Wide Social Media Network on Depression: County-Level Ecological Analysis\u201d  the authors made one addition.The correction will appear in the online version of the paper on the JMIR Publications website on April 11, 2023, together with the publication of this correction notice. Because this was made after submission to PubMed, PubMed Central, and other full-text repositories, the corrected article has also been resubmitted to those repositories."}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editors\u2019 attention by a concerned reader that the western blotting data shown in Fig. 3C were strikingly similar to data appearing in different form in another article by different authors at a diferent research institute. Owing to the fact that the contentious data in the above article were already under consideration for publication prior to its submission to"}
{"text": "Editorial Expression of Concern: Lasers Med Sci10.1007/s10103-021-03446-3After publication of this article , a readeThe authors have not responded to any correspondence from the editor or publisher about this Editorial Expression of Concern."}
{"text": "C. Spicer  In addition to the Acknowledgements given by the authors previously (reproduced below), the authors would also like to acknowledge funding from the National Institutes of Health (NIH), through grant #R01CA225002.Original Acknowledgements:S. T. acknowledges a PEER/PECRE Travel Grant from WestCHEM. R. R. acknowledges a Ramon y Cajal Contract from Ministerio de Econom\u00eda, Industria y Competitividad, Agencia estatal de investigacion, Universitat de les Illes Balears, Conselleria d'Innovacio, Recerca i Turisme, and the European Social Fund. I. A. M. acknowledges funding from the Spanish Government through grants TerMic (FIS2014-52486-R) and Contract (FIS2017-83709-R) and from Juan de la Cierva-f program. G. L. C. S. acknowledges funding from NIH RO1 CA173745. This work made use of the EPIC facility of Northwestern University's NUANCE Center, which has received support from the Soft and Hybrid Nanotechnology Experimental (SHyNE) Resource (NSF ECCS-1542205), the MRSEC program (NSF DMR-1720139) at the Materials Research Center, the International Institute for Nanotechnology (IIN), the Keck Foundation, and the State of Illinois, through the IIN.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Further understanding of the function and regulatory mechanism of cholinergic neural circuits and related neurodegenerative diseases.This review summarized the research progress of the central cholinergic nervous system, especially for the cholinergic circuit of the medial septal nucleus\u2010hippocampus, vertical branch of diagonal band\u2010hippocampus, basal nucleus of Meynert\u2010cerebral cortex cholinergic loop, amygdala, pedunculopontine nucleus, and striatum\u2010related cholinergic loops.The extensive and complex fiber projection of cholinergic neurons form the cholinergic neural circuits, which regulate several nuclei in the brain through neurotransmission and participate in learning and memory, attention, emotion, movement, etc. The loss of cholinergic neurotransmitters, the reduction, loss, and degeneration of cholinergic neurons or abnormal theta oscillations and cholinergic neural circuits can induce cognitive disorders such as AD, PD, PDD, and DLB.The projection and function of cholinergic fibers in some nuclei and the precise regulatory mechanisms of cholinergic neural circuits in the brain remain unclear. Further investigation of cholinergic fiber projections in various brain regions and the underlying mechanisms of the neural circuits are expected to open up new avenues for the prevention and treatment of senile neurodegenerative diseases. The central cholinergic nervous system is the main neurotransmitter system in the brain and is composed of cholinergic neurons that can synthesize acetylcholine (ACh). Acetylcholine transferase (ChAT) is a marker enzyme for cholinergic neurons, and acetylcholinesterase (AChE) is synthesized in cholinergic neurons. Cholinergic neurons are mainly distributed in the cerebral cortex, hippocampus, and basal forebrain. Downstream neurons projected by cholinergic fibers possess nicotinic acetylcholine receptors (nAChRs) and muscarinic acetylcholine receptors (mAChRs). Neurons at all levels are connected by synapses to form extensive and complex neural loops that participate in learning and memory, emotion, speech, and other skills.The cholinergic neurons in the brain can be divided into two types: local loop and projective. Local loop neurons are intermediate neurons that form a loop within the nucleus and do not project outside it. Local loop neurons are mainly located in the striatum, nucleus accumbens, olfactory tubercle, hippocampus, and cerebral cortex layers II\u2013V. The majority of cholinergic projection neurons are from the basal forebrain and brainstem to other brain regions, which constitute the basal forebrain and brainstem cholinergic system, respectively.Since the 1980s, the distribution and fiber projection of cholinergic neurons in the basal forebrain has attracted much attention.The brainstem cholinergic system consists of pontine tegmental cholinergic neurons and medulla oblongata cholinergic neurons. The pontine tegmental cholinergic system is mainly composed of cholinergic neurons in the interpeduncular tegmental area of the Ch5 group and the dorsolateral or lateral tegmental nucleus of the Ch6 group. The fibers are divided into the dorsal tegmental tract and ventral tegmental tract, which project to the thalamus, hypothalamus, globus pallidus, caudate putamen, and form a reticular ascending activation system together with other ascending fibers to participate in functional regulation, such as awakening and alertness of the body. Cholinergic neurons in the medulla oblongata are mainly located in the medial area of the facial nucleus of the ventral respiratory center of the medulla oblongata. nAChRs are distributed on the cell membrane of respiratory central neurons, which play a regulatory role in the function of the respiratory center of the medulla oblongata. In addition, the cell bodies and visceral motor fibers of cholinergic neurons in the cranial nucleus constitute the cranial nerve and participate in the regulation of somatic and visceral movement.Recent studies have shown that the central cholinergic nervous system, especially the highly complex basal forebrain cholinergic system, is not only related to cortical activation, emotion, attention, sensory coding, motivation, and memory but it is also involved in neural diseases, such as Alzheimer's disease (AD), Parkinson's disease (PD), schizophrenia, autism, attention deficit disorder, and drug abuse.The septal nucleus is the subcortical nucleus of the septum. The septum includes the structures under the corpus callosum and its surrounding area and is located in the medial wall of the cerebral hemisphere above the endplate and anterior commissure. According to spatialization,MS cholinergic neurons project from the medial septal nucleus and diagonal band nucleus through the hippocampal fimbria, dorsal fornix, and amygdaloid complex to the homotopic cortical targets in the hippocampus, as well as the entorhinal, cingulate, postsplenic, and hypothalamic cortices,The MS is a pacemaker of the hippocampal theta rhythm.The diagonal band of broca (DBB) is closely connected to the MS in terms of its structural organization. Besides the MS\u2010hippocampal cholinergic pathway, the connection between the vertical limb of the diagonal band and the hippocampus is another important cholinergic pathway. DBB is located on the dorsal and medial sides of the septum accumbens, alternating with the midline pellucid septum. At the back, the forelimb of anterior commissure protrudes, and DBB splits into a more dispersed structure, with interspersed fibers of gray matter stripes. Outside the parolfactory region, the direction of the white matter fibers in the DBB becomes more diagonal.Similar to the HDB, the CA2 subregion of the hippocampus is a relatively unexplored region in the human brain. A connection between MS\u2010VDB and CA2 has been identified in the mouse brain.In summary, the VDB projects cholinergic fibers to the hippocampal region through the MS and induces theta rhythms in the hippocampus, participating in the regulation of cognitive functions. Further investigations of the cholinergic loop projected from the horizontal and vertical branches of the diagonal band to the hippocampus is necessary, especially for understanding and treating cognitive disorders, such as DLB, PD, and AD.In addition to the MS/VDB\u2010hippocampal cholinergic circuit regulating theta oscillations related to neurodegenerative diseases, the basal forebrain\u2010cerebral cortex cholinergic circuit also involved in functions related to the Meynert basal nucleus (NBM). Chaves et\u00a0al.NBM is the main cholinergic nucleus in the Ch4 nucleus group of the basal forebrain, which is located on the anonymous substance and ventral side of the basal forebrain. Previous anatomical studies have shown that the NBM extends from the front of the olfactory tubercle to the uncinate hippocampus, with a length of 13\u201314\u2009mm in the sagittal plane, and provides most of the cholinergic innervation to the cerebral cortex. According to the characteristics of morphology and connectivity, the anterior, middle, and posterior NBM can be divided into four subregions: the anterior NBM, including the anteromedial (Ch4am) and anterolateral (Ch4a1) subregions; the middle NBM including the Ch4a1 and intermediate (Ch4i) subregions; and the posterior NBM, including the Ch4i and posterior (Ch4p) subregions.Selden et\u00a0al.More than 90% of large cell neurons in the NBM are cholinergic neurons. Studies have shown that the loss of cholinergic markers in the cerebral cortex and a decrease in the number of neurons in the basal forebrainOverall, the NBM is one of the most important cholinergic nuclei in the basal forebrain, playing a critical role in behavior, memory, attention, vision, and hallucination. Clinically, the DBS of NBM has been used to increase cholinergic fiber projection in the basal forebrain for the treatment of dementia. The method of using DBS to stimulate NBM through transmitting bioelectric impulses to restore distal cholinergic fiber projection can make up for the lack of cholinergic input from the NBM to the cortex, which is promising for the treatment of neurodegenerative diseases such as PDD and AD.As a part of the limbic system, the amygdala is a collection of nuclei located in the dorsomedial prefrontal lobe below the central cortex, top forward of the hippocampus, and the lower horn of the lateral ventricle. Three subregions are observed in neuroimaging of the human amygdala: dorsal, ventrolateral, and medial.The main motor regulatory area of the brainstem is located in the pedunculopontine tegmental nucleus (PPN), also known as the pedunculopontine nucleus (Ch5 group). PPN is situated in the rostral brainstem and is involved in motor circuits, primarily targeting the dorsolateral striatum.The cholinergic projections in brainstem originate from both PPN and laterodorsal tegmental nuclei (LDT), which together innervate the lateral hypothalamic area. The LDT, located in the caudal brainstem (Ch6 group), is associated with the limbic circuitry. Apart from targeting the dorsomedial striatum and the nucleus accumbens output, the majority of cholinergic neurons in the LDT also project to the anterior pretectal nucleus, anterior intralaminar nucleus, anterior ventral thalamic nucleus, dorsomedial thalamic nucleus, central medial thalamic nucleus, and habenular nucleus.Cholinergic intermediate neurons account for only a small portion of the total cells in the striatum, with 1\u20133% in rodents and 20%Recent studiesThe extensive and complex fiber projection of cholinergic neurons forms the cholinergic neural circuits, which regulate several nuclei in the brain through neurotransmission and participate in learning and memory, attention, emotion, movement, and so on. The loss of cholinergic neurotransmitters, the reduction, loss, and degeneration of cholinergic neurons or abnormal theta oscillations and cholinergic neural circuits can induce cognitive disorders such as AD, PD, PDD, and DLB. Further investigation of cholinergic fiber projections in various brain regions, such as MS, DBB, NBM, amygdala, and PPN, and further uncovering the underlying mechanisms of the neural circuits is critical to reveal the process of neurological diseases. However, the projection and function of cholinergic fibers in some nuclei of the brain, such as the HDB, SI, and medulla oblongata, remain unclear. The precise regulatory mechanisms of the cholinergic neural circuits in the brain also remain unclear. Furthermore, the diversity of postsynaptic cholinergic signaling pathways and heterogeneity of noncholinergic neurons has an unignorable influence on the study of neurological diseases. Therefore, to draw a more detailed topographic map of the central cholinergic nervous system, it is necessary to illuminate the projections of central cholinergic neurons and their modes of action. This will be helpful in the study of neural circuits and their regulation mechanisms for cognition, learning and memory, attention, sleep, fear, emotion, etc. However, with the aging of society becoming increasingly serious, PD, PDD, AD, and other senile cognitive disorders occur frequently. Further studies on the central cholinergic nervous system and its circuits are expected to open up new avenues for the prevention and treatment of senile neurodegenerative diseases.GH outlined and wrote the manuscript. HZ, HD and YL provided guidance throughout the writing of the article. All the authors read and approved the final manuscript.This work was supported by the Beijing Natural Science Foundation of China (7222250).The authors declare no conflict of interest."}
{"text": "This is a peer-review report submitted for the paper \u201cExercise-Induced Hypoalgesia Following Proprioceptive Neuromuscular Facilitation and Resistance Training Among Individuals With Shoulder Myofascial Pain: Randomized Controlled Trial\u201dThis paper  set to eThe paper holds several strengths, including random assignment and the inclusion of PNF, 2 resistance training exercise types, and 1 passive control group, which enables comparison across exercise conditions. Authors justifiably correct for multiple comparisons. The discussion thoroughly interprets the findings and relates them to existing literature. Some questions and potential limitations are listed below.1. The study is limited to young women (18-30 years old) and therefore has limited generalizability to men, as well as women above the age of 30 years. Authors partially acknowledge this in the limitations section (with regard to gender).2. The sample size in each group is modest (n=18-20), limiting statistical power.3. Did the authors have a specific hypothesis about the relative effect of PNF, isometric, and isotonic exercise training on outcomes? Such a hypothesis is now stated. Was the testing of differential effects exploratory?4. Authors indicate that \u201cRandomized sequences were generated by computer.\u201d Can authors provide details on the method, software, or website used for randomization?5. Authors indicate that participants were excluded if they experienced depression, psychosis, cognitive impairment, etc. How were these assessed?6. Authors make use of 6 different acronyms in the abstract, which may make it more difficult to read, particularly for individuals outside this immediate field. When possible, consider spelling things out to increase ease of readability.P<.000\u201d to \u201cP<.001\u201d7. Please change all instances of \u201c8. There are some typos throughout the manuscript, please correct those .Thank you for revising the manuscript. The authors have addressed my concerns."}
{"text": "Transparency Needed for Economic Analyses of PA Programs Dear Editor, I am writing in response to the article Pharmacoeconomic Modeling of Prior-Authorization Intervention for COX-2 Specific Inhibitors in a 3-Tier Copay Plan in the July/August 2003 issue of the Journal of Managed Care Pharmacy. 1 While the authors are to be commended for using an economic analysis to assess the impact of a prior-authorization (PA) program, I have some objections with the paper that I wish to express. My primary objection addresses the lack of transparency in methods used."}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editor's attention by a concerned reader that certain of the cell migration and invasion assay data shown in Figs. 2C and 5C were strikingly similar to data appearing in different form in other articles by different authors at different research institutes, several of which have been retracted. Owing to the fact that the contentious data in the above article were already under consideration for publication, or had already been published, prior to its submission to"}
{"text": "Values were obtained on the test stand with an innovative deflector built into the distributor head at three angles of inclination . Statistical analyses revealed a significant effect of airflow velocity and deflector angle, which corrects the deviation from the vertical plane of the distributor head, on the uniformity of seed sowing. In addition, regression equations were determined to predict the quality of the seed sowing process. The developed and manufactured innovative distributor head with a deflector that tilts in two planes, designed to improve the distribution evenness of the air stream transporting seed to individual coulters in pneumatic seed drills, received a positive review. The use of a deflector with automatic control of its position angle, correcting the deviation of the distributor head from a vertical plane in pneumatic seed drills improves the uniformity of seeding. Therefore, it is reasonable to use this solution for new pneumatic seed drills and those in use on soils with different relief (undulating surface). Moreover, the solution fits in with modern agricultural manufacturing in accordance with the ideas of precision agriculture.This paper presents an innovative solution for a distributor head equipped with a deflector (controlled plate)\u2014intended to change the tilt angle  of the pneumatic seed drill distributor head cover. We compared two qualitative parameters of seed sowing, coefficient of variation and coefficient of lateral unevenness of seed sowing ( Distribution of the main seed stream to the individual seed conduits takes place in a separation device, called a distributor head. The head should be designed to divide the main seed stream into equal unit streams, which travel to the rows in the soil through seed tubes and coulters. The distribution principle of the heads is based on the vortex interaction of the turbulent air stream with the seed and the resulting stochastic distribution of the seed4, have disadvantages. The most important of them is low lateral sowing evenness6, especially in terrain with varied terrain (hills)1.Pneumatic seed drills, despite their numerous advantages including high efficiency, maneuverability, easy and fast loading of seed8. There are also studies which prove that uniform distribution of seeds in the soil has a positive effect on the crop quantity and quality by improving utilization of sun rays and water by growing plants9. Moreover, intraspecific competition is reduced as plants have a similar life space. Authors of these studies use various indicators, test procedures11 and methods of seed uniformity assessment14 to evaluate the process of machine seeding. Pippig has analyzed the influence of technical parameters of pneumatic seeding system units and found that the diffuser tube length should be about 350\u00a0mm to maintain acceptable uniformity of seeding15. Subsequent studies indicate the distribution of air flow velocities at the outlet of the seed (pneumatic) tube, which is necessary to validate the mathematical model of two-phase flow mechanics in pneumatic seed drill systems5, and proposes minimum seed transport velocities16. From the analysis of the literature, it appears that the uniformity of seed distribution is also influenced, though minimally (2\u00b0\u20133\u00b0), by inclination of the seed-air stream distributing head17. There is also research whose results are mathematical models describing evenness of the seed distribution in the distributor head18. Other researchers work on improving or developing new sowing system designs5 as well as using electronic optical systems to control the sowing process19. Xiaolong et al.20 designed and tested a new pneumatic precision centralized seed dispenser with internal seed loading, which sows six rows simultaneously. The authors explored the influence of design and operational parameters on sowing evenness. Karayel et al.21 developed a new helicoidal seed tube where falling seeds move along a seed spiral which improves seed distribution uniformity. The tests were conducted for two species of wheat and barley grains. The values of variability coefficient for the grain species changed from the level of 118.4% and 139.5% to the level of 77.2% and 70.6%21, respectively. In another study the authors developed and tested in field conditions a contactless, self-priming system for wheat seed injection. The value of seed distribution uniformity variability coefficient was 11.3%22. Xi et al23 discussed a different approach to the issue of seed distribution uniformity improvement by proposing a seed sowing system without seed delivery tubes whose clearance is 5.0\u20138.8\u00a0cm. The best qualitative parameters of seed sowing were found for 7.0\u00a0cm clearance tubes\u2014sowing accuracy was 83.84%, whereas the seed distribution uniformity variability coefficient was 14.68%. The research, however, did not consider a varied terrain (slope). Some simulation research on the seed mixture movement and the air stream coming out of the dispenser was conducted by Zhou et al.24, Xiaolong et al.25 and Bourges et al.26. That research involved distribution of the seed-air stream flow in the distributor head. Unfortunately, the authors did not investigate evenness of the dosed air stream distribution with the head tilted from the vertical\u2014head tilt. Kumar et al. carried out research on the effect of the distributor head shape, outlet air stream velocity and sowing unit operation speed on seed distribution evenness. The authors indicated that sowing evenness is influenced by the velocity of the air stream transporting the seed, sowing rate, and the seed physical properties. From the literature analysis, it can be concluded that the research results and their scope are not conclusive and do not exhaust the subject of seed sowing evenness in machine sowing. Therefore, it may be stated that there is still a problem of even seed-air stream flow distribution, especially when sowing seeds in soils with varying terrain\u2014especially on slopes above 10\u00b0. According to the research conducted so far28, the deviation from the vertical of a mechanical-pneumatic seed drill distributor head has a significant effect on the seed flow distribution uniformity inside its head, and the distributor head deviation from the vertical in the range of 0\u00b0\u201320\u00b0 significantly worsens the coefficient of lateral seed sowing unevenness, up to 14%27. Gierz \u0141ukasz and Markowski Piotr29 achieved similar correlations for sowing oat seeds. The distributor head deviation from the vertical by an angle of 10\u00b0 resulted in a 31% evenness deterioration of oat seed sowing (evenness of seed and air stream distribution in the distributor head) from a value of 10.36% at the vertical position of the distributor head to a value of 13.55% at the deviation by an angle of 10\u00b0. Yatskul et al.30 noticed a similar relationship when sowing wheat seed and tilting the distribution head by an angle from 0\u00b0 to 22\u00b0.In the literature there are many papers concerning the causes of unevenness of seed sowing performed with pneumatic seed drills31.For the selected orientation, the head cover tilt in relation to the diffusion tube vertical axis, can result in more seed being carried in that direction, i.e. asymmetrical seed-air stream distribution. Distributor heads of commonly used pneumatic drills usually are not equipped with seed direction control, and it is not possible to change the seed reflection angle. Another disadvantage of assessing the machine sowing quality noted by the authors is the use of several methods (field and laboratory) to estimate the seed sowing evenness, which makes it difficult and sometimes even impossible to compare the results presented in the respective articles. Therefore, it is not always possible to make an unambiguous evaluation of the influence of the sowing unit individual design and operational factors on the seed sowing evenness. It needs, however, to be noted that regulations included in ISO (7256-1:1984) 28 norm are helpful for unification of methods used for evaluation of seed sowing quality and make it possible to compare the results of variability coefficient (CV) for different grain species\u03b4.The authors present evaluation of lateral seed distribution evenness with a pneumatic seed drill using an innovative method of correcting the setting of the distributor head cover of the pneumatic sowing system by means of a controlled plate (deflector), which makes it possible to control the distribution of the seed-air stream by changing the seed reflection angle. To be able to compare the obtained results with those presented in the literature, two coefficients were used to assess the quality of seed sowing\u2014coefficient of variation CV and coefficient of lateral seed sowing unevenness 28. The deflector's design allows it to be tilted in two planes\u2014in two perpendicular axes. The deflector tilt angle from the distributor head parallel plane is controlled by three screws numbered 2, 3, 4  The main fan (8) is connected to the dosing unit with injector (1) via airflow supply conduit (9).The laboratory test bench for evaluating the quality of seed sowing Fig.\u00a0 was consThe laboratory test bench is also equipped with a unit for automatic weighing of the quantity of seed sown, a 16-chamber seed collection box and a computer with software for data collection and calculation of the coefficient of lateral seed sowing unevenness.In this study, oat seed Lion with a thousand-seed weight of 32.2\u00a0g\u2009\u00b1\u20090.62 and moisture content of 9.9% was used. The research material came from Main Seed Warehouse Top Farms Seeds, Production Plant in Run\u00f3w located in Greater Poland Province. Based on the announcement of the Marshal of the Sejm of the Republic of Poland on the announcement of the uniform text of the Act on the legal protection of plant varieties of January 22, 2021  and the breeder's declaration that the indicated variety: Lion (oat) is law protected by the breeder, the authors have received this permission. The breeder agrees to obtain the above-mentioned plant material, which complies with the national guidelines from Main Seed Warehouse Top Farms Seeds, Production Plant in Run\u00f3w located in Greater Poland Province. The authors, with the breeder's consent, may use its plant material only for the purposes of scientific and research activities, including carrying out tests of e.g. sowing simulation on a laboratory stand with an innovative distributor head with a deflector. Seeds were sown at a constant rate of 250\u00a0kg/ha.Once the laboratory experiment (one measuring cycle) is completed on the designed test rig, the 16 chambers of seed collecting box (7) are opened sequentially and their contents are weighed and returned in a closed circuit to seed box (12).Sliders are installed in the chamber bottoms of collection box (7) and are opened and closed by a cam mechanism driven by toothed belt through servomotor (23). A special program for the laboratory rig written in Embarcadero's RAD Delphi 2010 environment controls the servomotor (23), the main fan supply motor (21), suction fan (18), and dispenser drive motor (28).35. The whole measurement cycle of the sown seed weight is completely automated and after weighing the seed in all sixteen chambers of the collection box, a test report is generated, and the results are stored in .txt files.Collector pipe is located along the sixteen-chamber box, into which the seeds enter when the sliders are opened. The seeds then are transported by air stream through the suction conduit from the collector pipe to the separating cyclone located above seed box (12). The conical bottom of separation cyclone (15) is closed from below by flap (17). It relies on three tensometric sensors, which measure separately the weight of seeds from each chamber in collection box (7) with an accuracy of\u2009\u00b1\u20090.005\u00a0kg. Cyclone flap (17) is closed by the vacuum in the system with a force of approx. 500\u00a0N during the seed transport from collection box (7), then after suction blower (18) is switched off, the conical bottom of the cyclone drops onto the strain gauges. Cyclone flap (17) is locked electromagnetically by the control systemRead the test parameters written into the control system interface: airflow rate, sowing time;Turn on the main fan motor and wait for its speed to stabilize;Make sure that the cam mechanism is before chamber 1;Regulate the fan shaft speed so that the assumed airflow speed is achieved at the inlet of the seed dosing unit;Start the sowing (dosing) unit and set the desired speed of the sowing (dosing) shaft;Wait 5\u00a0s. for the sowing conditions to be established;Direct the seed into the distribution head with the innovative deflector;Keep sowing for a set time\u2014according to the test plan, about 10\u2013600\u00a0s.Switch off the sowing unit drive and after 5\u00a0s switch on the main fan motor;Start the suction fan;Check the vacuum value in the batch measuring system cyclone;Open another collection box slider;Wait 30\u00a0s;Turn off the suction fan;Read the weight of the seed sown from a tensiometer weight scale measuring the weight of seed batch;Read the weight of all the seed from the tensiometer weight of the seed box;Open the flap that closes the seed outlet in the cyclone;If the extreme position of cam mechanism carriage is reached, return to chamber no.1;Compile the measurement results and save them in a database.The laboratory test bench with the innovative deflector is equipped with a control system, in which the measurement cycle is programmed according to the following scheme:35. The measuring interface is equipped with a terminal block, where serial transmission conduits (USB2), four digital outputs (DO0\u2026DO3) and six analogue inputs (AI0\u2026AI6) are used to control the device  consists of inputting fixed parameter values in accordance with the test plan after the main dialogue form appears i.e. sowing time. The sowing speed is read from working speed sensor (9) and has also been presumed to be constant. The length of the measuring distance is determined by the sowing time and working speed (sowing rate) specified in the test plan. Measurement procedure 2  involves cyclic opening of the individual box chambers, weight measurement and discharge into the seed box, and the recording of the measured values of the seed weight in the program memory to create a report.The software uses a proprietary graphics and mathematics library, graphics_v3, which complement the control systemThere were three repetitions of the experiment for all combinations of variable parameters according to the algorithm shown in Fig.\u00a0sowing rate of 250\u00a0kg/ha;sowing speed 8\u00a0km/h;sowing time 10\u00a0min.Constant:air velocity in three ranges: 12.22\u00a0m/s, 14.44\u00a0m/s, 16.66\u00a0m/s;distribution head tilt: 0\u00b0, 5\u00b0, 10\u00b0;deflector tilt: 0\u00b0, 5\u00b0, 10\u00b0.Variables:CV (%);coefficient of variation \u03b4 (%).coefficient of lateral seed sowing unevenness Actual parameters:For the purposes of this study, the following parameters were adopted:\u03b436 is frequently determined as variability coefficient (CV)37, defined as a ratio of square deviation of average distance between seeds sown in particular rows to the average distance determined for the whole seed drill. This indicator can be also determined as a ratio of square deviation of the seed average weight falling on a measurement distance in individual rows to an average weight for the whole seed drill. In turn, an indicator of lateral unevenness of seed sowing is defined as a ratio of square average deviation in a row to average deviation in a row38. The indicator of lateral seed sowing unevenness is commonly defined for point seed drills38.The quality of sowing (seed distribution evenness) is evaluated based on the values of transverse and lateral unevenness of seed sowing. The indicator of transverse seed sowing \u03b4 were applied. Coefficient of variation (CV) was calculated from relation  and coefficient of lateral seed sowing unevenness relation , accordi\u03b4 (%) was determined from Eq.\u00a0. qsr\u2014average weight of oat seed sown in the ith container (kg), \u2206qsr\u2014the average deviation in weight of seed sown into seed containers (kg).The coefficient value of lateral seed sowing unevenness from Eq.\u00a0, accordi39.The air velocity was set in 3 ranges: 12.22\u00a0m/s, 14.44\u00a0m/s, 16.66\u00a0m/s due to the oats seed critical velocity of 8.03\u00a0m/s0: the correlation coefficients between the variables are equal to zero. When the values of the correlation coefficients showed a strong relationship between the independent variables and the dependent ones, rectilinear regression equations were determined at a further stage to describe the nature of the relationship. Fifth-degree curvilinear, multiple, multivariate polynomial, second-degree polynomial and power equations were tested as well, followed by regression analysis with a posteriori elimination and stepwise selection procedures to determine the form of the regression equation describing the most accurate fit of the empirical data to the model. Regression function fit assessment was determined, and description quality analyses were performed by removing irrelevant variables from the equations. The calculated value of the F-Snedecor statistic and the probability of exceeding it, the multiple correlation coefficient, the value of the determination coefficient, the standard deviation of the residuals and the coefficient of random variation were used as criteria for assessing the model fit to the empirical data. The rule that functional relationships should occur in simple mathematical forms was also considered for determining the final form of the function. A statistical analysis was performed using the Statistica 13 PL statistical software package. The significance level in the analysis and inference was set at p\u2009=\u20090.05.Measurement results were statistically analyzed. A correlation analysis was conducted to determine the strength and nature of the relationship between the independent variables and the dependent ones. The following null hypothesis was verified H\u03b4) at three values of angles  of distributor head tilt from the vertical and deflector tilt from the distributor head.During the experiment, the seed weight distribution to each coulter was determined in the distributor head and the values of seed sowing quality coefficients were calculated, i.e. the coefficient of variation (CV) and coefficient of lateral seed sowing unevenness  and the coefficient of lateral seed sowing unevenness (\u03b4\u2009=\u200924.42%) occurred for the airflow velocity of 14.4\u00a0m/s, the distributor head angle of 5\u00b0 from the vertical and the deflector angle from the distributor head of 5\u00b0\u2014a statistically significant difference at \u03b1\u2009=\u20090.05 (Tables\u00a0\u03b4) are close to the calculated values of these quality coefficients when the distribution head is vertical. An analysis of results also shows that an increase in air velocity in the pneumatic seed transport system to 16.6\u00a0m/s results in a deterioration of seed sowing quality, regardless of the applied combination of distribution head and deflector tilt angles.Convergence can also be found between the results of the coefficient values of the seed sowing unevenness within the velocity increase range from 12.2 to 14.4\u00a0m/s with the results reported in the following articles5 Tables\u00a0. The obt42, can negatively affect the obtained crop yield. It is, therefore, reasonable to use a deflector to improve the quality of sowing with a pneumatic seed drill, especially when sowing in fields with an angle of terrain greater than 5\u00b0 \u2014Eq.\u00a0v) in the pneumatic seed transport system, distribution head tilt from the vertical (h\u03b2) and the angle of the deflector in relation to the distributor head (d\u03b1).Based on the obtained results, regression equations were derived with a posteriori elimination procedure and stepwise selection of insignificant variables and polynomial degree, describing the functional dependence of seed sowing quality, i.e. coefficient of sowing variation (CV)\u2014Eq.\u00a02) of the equations obtained was 0.94 and 0.91 respectively. These high values of the determination coefficient indicate a good match of the developed models with the empirical data, which allows prediction of the sowing process quality depending on the velocity of air stream (v) in the pneumatic seed transport system, distribution head tilt angle from the vertical (h\u03b2) and the deflector tilt angle relative to distribution head (d\u03b1).Quadratic equations of seed sowing quality obtained from regression analysis are characterized by a very good model match with empirical data. The values of the coefficient of determination (R\u03b4)\u2014Eq.\u00a0Graphical representation of quadratic equations describing the quality of seed sowing (coefficient of sowing variation (CV)\u2014Eq.\u00a0The experiment also determined the distribution of seed weight in the distribution head for individual coulters. The average seed weight for one coulter at airflow velocity of 12.2\u00a0m/s varied from 0.99\u00a0kg\u2009\u00b1\u20090.012\u00a0kg to 1.12\u00a0kg\u2009\u00b1\u20090.021\u00a0kg, depending on the distribution head and deflector angles. With an airflow velocity of 14.4\u00a0m/s, the mass of seed sown per coulter varied from 1.00\u00a0kg\u2009\u00b1\u20090.018\u00a0kg to 1.19\u00a0kg\u2009\u00b1\u20090.027\u00a0kg. In the third case, highest air flow velocity in the pneumatic system of 16.6\u00a0m/s, the average weight of seed directed to individual coulters varied from 1.00\u00a0kg\u2009\u00b1\u20090.021\u00a0kg to 1.12\u00a0kg\u2009\u00b1\u20090.032\u00a0kg (Table\u00a0d\u03b1) and tilt angle of the seed-air stream distributor head (h\u03b2) along with the calculated values of the seed quality coefficients, i.e. coefficient of sowing variation (CV) and the coefficient of lateral seed sowing unevenness (\u03b4) and air stream velocity 14.4\u00a0m/s\u2014at which the highest seed sowing evenness .Figures\u00a0\u03b4 (33.61% and 29.61% respectively), i.e. the most uneven seed sowing was observed with a distribution head angle of 10\u00b0 from the vertical and a deflector angle of 0\u00b0   from 0\u00b0 to 10\u00b0, with a distribution head angle of 10\u00b0 from the vertical  obtained at a deflector angle of 5\u00b0 and a distribution head angle of 5\u00b0 from the vertical  were 25.73% and 21.51%, respectively.The highest CV and or) Fig.\u00a0. Deflectcal Fig.\u00a0 improvedcal Fig.\u00a0. The CV The developed and manufactured innovative distributor head with a deflector that tilts in two planes, designed to improve the distribution evenness of the air stream transporting seed to individual coulters in pneumatic seed drills, provided positive results in this experiment.Changing the deflector tilt angle significantly affects the value of the coefficient of lateral seed sowing unevenness and can compensate for the effect of the seed drill tilt and the supply conduit spreader curvature. Change in the distributor head angle of tilt from the vertical position (0\u00b0) by 5\u00b0 and 10\u00b0, accompanied with appropriate change in the deflector angle by the above given angles, that is, 5\u00b0 and 10\u00b0 caused reduction in the value of the sowing lateral unevenness indicator from about 20% up to above 40%, depending on the working speed and indicator applied.\u03b4) was obtained for air velocity of 14.4\u00a0m/s. Changing the air velocity from 14.4 to 12.2\u00a0m/s or 16.6\u00a0m/s significantly worsened the seed distribution evenness in the distributor head\u2014increase in the value of indicators of seed sowing lateral unevenness within the range from about 5% to about 18%.The research result analysis shows that the air stream velocity transporting the seed has a significant influence on the uniformity of air stream distribution in the distributor head. The lowest value of the seed sowing quality coefficient, i.e. coefficient of sowing variation (CV) and the coefficient of lateral seed sowing unevenness (\u03b4), is characterized by a high percentage of explained variability . This definitely confirms usefulness of the equations for prediction of the seed sowing process quality as a function of the airflow stream velocity (v) in the pneumatic seed transport system, the deviation of the distributor head from the vertical (h\u03b2) and the deflector tilt angle relative to the distributor head (d\u03b1).The second-degree equations of seed sowing quality determined from a multiple regression analysis, i.e. coefficient of sowing variation (CV) and the coefficient of lateral seed sowing unevenness (43 or by incremental manufacturing44. These topics may be the subject of further research.The research results indicate that it is reasonable to improve the quality of sowing with pneumatic seed drills, especially when sowing in areas with an over 5\u00b0 inclination. This requires continuous measurement of the asymmetry coefficient of the seed stream distribution in the head seed distributor and the use of a system for automatic adjustment of the deflector angle that can be performed by the increasingly used 3D printing method"}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of the above paper, it was drawn to the Editors' attention by a concerned reader that one of the tumor images shown in Fig. 4A was strikingly similar to a tumor image appearing in a pair of other articles that had been written by different authors at different research institutes. Owing to the fact that the contentious data in the above article had already been published elsewhere prior to its submission to"}
{"text": "Following the publication of this article , concernThe University of California, Davis confirmed that author DPW admitted to manipulation of the data underlying the results presented in Fig 2.PLOS Genetics Editors issue this Expression of Concern to notify readers of the above issues.The authors are working with PLOS to try and address these issues. Meanwhile, the"}
{"text": "The authors wish to make the following corrections to this paper . In the The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "There was an error in the original publication . We usedTherefore, two minor modifications have been made:Section 2.2. Outcomes, last paragraph:A correction has been made to \u201cBecause the pre-determined chest compression depth target was not reached during this study, an additional chest compression depth outcome considering an arbitrary target (\u22653 cm) based on the mean compression\u2019s depth rather than the guidelines was added post hoc.\u201dSection 4. Discussion, paragraph number 3:A correction has been made to \u201cThe cut-off used to determine whether chest compression depth was adequate was decided according to the manikin\u2019s size. Since the initial analysis showed that compression depth was consistently shallower than expected, a supplementary secondary outcome was added post hoc using an arbitrary target of \u22653 cm (based on the mean compressions\u2019 depth) to define adequate compression depth. No significant difference was found depending on the guidelines used, but the issue of manikin fidelity should nevertheless be considered. Indeed, high-fidelity simulations have been shown to improve compression quality [28], and manikins\u2019 limitations should be clearly acknowledged by their manufacturers, who should strive to increase the fidelity of their simulation materials.\u201dIn the original publication , there wThe authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "The above article, published online on 5 December 2022, on Wiley Online Library (wileyonlinelibrary.com), has been withdrawn by agreement between the authors, The American Association of Physicists in Medicine and Wiley Periodicals, LLC. The withdrawal has been agreed due to a technical error at the publisher that caused the article to be mistakenly published online although publication had been canceled because the authors did not approve their proof. The publisher regrets the error. Withdrawal: Erli Chen, Michael D. Mills, John A. Antolak, Ivan M. Buzurovic, William Dezarn, Farhana R. Khan, Charles Kirby, Brent Parker, Todd Pawlicki, Zhong Su, Chrisine M. Swanson, Russell B. Tarver, Bruce Tomadsen, Nicholai E. Wingreen, Susan White, Ming Yang, Sumin Zhou, \u201cThe current state, future supply and demand of therapy physicists \u2010 A special report of the 2020 AAPM therapy physicist workforce survey results,\u201d Journal of Applied Clinical Medical Physics,"}
{"text": "In the original publication , there wThe authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "Retraction Note: World J Surg Oncol 21, 217 (2023)https://doi.org/10.1186/s12957-023-03114-6The authors have retracted this article because they found that the presented data had been fabricated.All authors agree to this retraction."}
{"text": "The authors regret that the following funding information was omitted in the original manuscript:\u201cThis project has received funding from the European Union\u2019s Horizon 2020 research and innovation programme under grant agreement GrapheneCore3 \u2013 881603.\u201dThe Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "The journal retracts the 15 March 2017 article cited above.Following publication, concerns were raised regarding the integrity of the images in the published figures, with areas of image duplication and manipulation in Figures 1B, 3A. Following a request for raw data, further issues were identified in Figures 5A, B, H. The authors failed to provide a satisfactory explanation during the investigation, which was conducted in accordance with Frontiers' policies. As a result, the data and conclusions of the article have been deemed unreliable and the article has been retracted.This retraction was approved by the Chief Editors of Frontiers in Molecular Neuroscience and the Chief Executive Editor of Frontiers. The corresponding author Carmela Matrone did not agree to the retraction. Helle Rasmussen agreed to the retraction. The remaining authors did not respond to our correspondence."}
{"text": "Correction: Trials 24, 174 (2023)https://doi.org/10.1186/s13063-023-07188-1The original publication of this article  containeIncorrectThis project has received funding from European Social Fund (project No: 01.2.2-LMT-K-718-03-0072) under grant agreement with the Research Council of Lithuania (LMTLT).CorrectThe project has received funding from European Regional Development Fund (project No: 01.2.2-LMT-K-718-03-0072) under a grant agreement with the Research Council of Lithuania (LMTLT)"}
{"text": "Correction: Cell Biosci (2019) 9:34 https://doi.org/10.1186/s13578-019-0296-9The position of DAPI panels in Fig.\u00a04g was reversed. The authors would like to provide a revised Fig. 4g with reorganized DAPI panels.The Emerin blot of Fig.\u00a02c was the unpublished data from the same Co-IP experiment published in Wang et al. . The autIn the original version of the article, the authors wish to make the following corrections:The correct version of figures is given in this correction."}
{"text": "Retraction Note: J Exp Clin Cancer Res 38, 344 (2019)10.1186/s13046-019-1332-7The Editor-in-Chief has retracted this article. After publication, concerns were raised regarding highly similar features in the published images. Specifically:\u2022 Fig. 2f Invasion si-NC and MACC1-AS1 images appear to contain some highly similar areas;\u2022 Fig. 2f Invasion si-MACC1-AS1 and pWPXL images appear to contain an overlapping area;\u2022 Fig. 5a appears to contain some duplicated patterns within each image.Additionally, Fig.\u00a03a appears highly similar to Fig.\u00a03e in , and FigFurther checks by the publisher have also found that there appear to be duplicated western blot bands and background features in Fig.\u00a03a, signs of erased bands in Fig.\u00a03e, and background irregularities in Fig.\u00a06b and c. In addition, a number of images in Fig.\u00a02f appear highly similar to those in Fig. S1a and c in [The Editor-in-Chief therefore no longer has confidence in the presented data.Jiang Jianshuai has stated on behalf of all co-authors that they agree to this retraction."}
{"text": "Biol Pharm Bull 35: 1574-1580, 2012]. Finally, it was pointed out that some of the western blot images presented in Fig. 4B in the above paper had also apparently been featured in different formats in two other publications that also contained several of the same authors.Following the publication of the above paper, an interested reader drew to our attention that a number of apparent anomalies existed with the data presented in the above paper. First, there appeared to be strikingly similar and duplicated patternings of the cells within the cellular images featured in Fig. 2, images 3 and 4 . Secondly, certain of the data panels shown in Fig. 4 appeared to be strikingly similar to data shown in Fig. 4 in a previously published paper, which featured several of the same authors [Lin X, Liu X, Huang Q, Zhang S, Zheng L, Wei L, He M, Jiao Y, Huang J, Fu S Experimental and Therapeutic Medicine has been able to verify the claims made by the interested reader; therefore, in view of the number of potential anomalies that have been identified and owing to a lack of overall confidence in the presented data, the Editorial Board have decided to retract the above paper from the publication. The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a satisfactory reply. The Editor apologizes to the readership of the Journal for any inconvenience caused.Following an internal enquiry, the Editor of"}
{"text": "We examined the gender distribution of authors of retracted articles in 134 medical journals across 10 disciplines, compared it with the gender distribution of authors of all published articles, and found that women were underrepresented among authors of retracted articles, and, in particular, of articles retracted for misconduct. There is extensive literature highlighting the inequalities experienced by female researchers throughout their academic careers -3. By coIn this study, we compared the representation of female first and last authors in retracted articles and all publications by examining 134 medical journals.publications, we used the results of Hart and Perlis [retractions, we retrieved all PubMed articles published in these journals between January 2003 and December 2022 that were retracted. We evaluated the 2003-2022 period to have a sufficiently large sample size. We retrieved the reason(s) for retraction using the Retraction Watch database and grouped the 102 reasons into 4 main reasons: scientific misconduct only, error(s) only, scientific misconduct and error(s), and reason not related to the author(s). We used the Gender API software to determine first and last authors\u2019 gender [d Perlis , which c\u2019 gender  and, if We computed the proportion of retractions and stratified the results by gender and discipline. To exclude ambiguous names that could skew the gender distribution, we repeated the analyses with retractions whose authors\u2019 gender was determined with >60% or >70% accuracy ,3. Data Since this study did not involve the collection of personal health-related data, it did not require ethical review, according to current Swiss law.After excluding anonymous retracted articles and those with first names as initials, gender could be determined for 398 first authors and 395 last authors. Women were first or last authors of 100 (25.1%) and 55 (13.9%) retractions, respectively, while their proportion as first or last authors of all publications was 41.3% and 26.1% in 2008 and 45.4% and 33.4% in 2017, respectively.The proportion of female first and last authors of all publications was higher in 2017 than in 2008 for all 10 disciplines. The proportion of women was lower for retractions compared to all publications for all 10 disciplines for first authors and 7 disciplines for last authors.As shown in The results were similar when using subsamples. For example, the proportion of female first and last authors of retractions was 24.3% (93/383) and 13.8% (53/383), respectively, when the authors\u2019 gender was determined with an accuracy of >60%. It was 24.6% (90/366) and 14% (53/379), respectively, when accuracy was >70%.We found that women were underrepresented among authors of retracted articles, and, in particular, of articles retracted for misconduct.Compared with the study by Pinho-Gomes et al , the proRetractions for misconduct can be seen as proxies for scientific integrity, and our results suggest that it varies with gender. Identifying the underlying reasons for these gender disparities is challenging. No studies had directly tackled this topic, making it difficult to draw conclusive findings. Biological, social, and cultural factors can interact in a complex way and contribute to the more pronounced competitive tendencies of men versus women, which can be a possible risk factor for misconduct . AlternaOur study has two main limitations. Gender was determined using Gender API and a manual search instead of self-identification. We dichotomized gender into female and male, which did not allow us to assess nonbinary identity."}
{"text": "Retraction Note: Journal of Nanobiotechnology (2020) 18:7110.1186/s12951-020-00626-1The Editors-in-Chief have retracted this article. After publication, concerns were raised regarding the images presented in the figures. Specifically:Figure\u00a08a western blots appear to have vertical breaks in the backgrounds.Figure\u00a012 Liver CUR and RPCNP-CUR images contain a highly similar area (rotated).The authors have stated that some lanes have been removed from the western blots to exclude irrelevant samples, and that an incorrect image was used in Fig.\u00a012 by mistake. However, the authors have been unable to provide the underlying raw data upon request. The Editors-in-Chief therefore no longer have confidence in the presented data.Chunhong Gao and Yang Yang have not explicitly stated whether they agree to this retraction. None of the other authors have responded to any correspondence from the publisher about this retraction."}
{"text": "Following the publication of this article , concernThe following panels appear similar:The Fig. 4A HepG2 Tubulin and MCF Tubulin panels.The Fig. 7A HepG2 Tubulin and MCF Tubulin panels.Lanes 1\u20134 of the Fig. 1D Tubulin panel of this study .The Fig. 4A MCF p-AKT panel of this study , lanes 3The Fig. 4A MCF7 ERK panel of this study  and laneLanes 1\u20133 of the Fig. 5A MCF7 p-JAK2 of this study [Lanes 1\u20132 of the Fig. 6A MCF7 Input STAT3 panel of this study [The Fig. 6B MCF7 Lysate p-STAT3 panel of this study  and laneLanes 2\u20134 of the Fig. 6B HepG2 Lysate p-STAT3 panel of this study  and the The Fig. 6B MCF7 STAT3 panel of this study  and the The Fig. 6B HepG2 Lysate APPL1 panel of this study .Lanes 2\u20135 of the Fig. 7A HepG2 p-STAT3 panel of this study  and the Lanes 1\u20133 of the Fig. 7A MCF7 p-AKT panel of this study [Lanes 1\u20134 of the Fig. 7A MCF7 AKT panel of this study .The corresponding author commented that some western blot images were misused in this article  and requPLOS ONE Editors retract this article.In light of the concerns affecting multiple figure panels that question the integrity of these data, the CW agreed with the retraction. YD, YC, BW, LW, YZ, DZ, XC, and ML either did not respond directly or could not be reached."}
{"text": "Cell Death and Disease 10.1038/cddis.2017.356, published online 17 August 2017Retraction to: In Fig. 2E and F, the NC images appear to contain overlap.There appear to be a number of overlapping images in Figs. 3A-D and 6E and F.L02 and SMMC-7721 cell lines have been reported to be contaminated with HeLa and are therefore unsuitable for liver cancer research.HepG2 cells have been reported to be unsuitable as a model of hepatocellular carcinoma.The Editors have retracted this article. After publication, concerns were raised regarding overlap in the migration and invasion assay images presented in the figures, as well as the cell lines used in the study. Specifically:The authors have checked the original data and stated that the image errors occurred due to incorrect data storage. The Editors and authors therefore no longer have confidence in the presented data.Chao Yang has stated on behalf of all authors that they agree to this retraction."}
{"text": "Following the publication of this article , concern\u25cb Lanes 2\u20135 of the Fig 7F IB:IKK\u03b1 panel and lanes 1\u20134 of the Fig 7J IB: STAT3 panel when flipped vertically.\u25cb Lanes 1\u20133 of the Fig 2A IB:\u03b1-tubulin panel of this study [Tyr1007/8 panel of this study [Thr172 panel of [\u25cb Lanes 2\u20134 of the Fig 2F IB: pJak2\u25cb Lanes 1\u20134 of the Fig 3H IB:\u03b1-tubulin panel of this study [\u25cb Lanes 2\u20135 of the Fig 6B IB:\u03b1-tubulin panel of this study  and the \u25cb The Fig 8G IB: \u03b1-tubulin panel of this study  and the \u25cb The Fig 8H IB: \u03b1-tubulin panel of this study  and the The following western blot panels appear similar:\u25cb The left half of the top DAPI panel, and the right half of the middle DAPI panel.\u25cb The left half of the top IL-6R panel, and the right half of the middle IL-6R panel panel.\u25cb The left half of the IKK\u03b2 panel, and the right half of the PERK panel.\u25cb The left half of the top Merge panel, and the right half of the middle Merge panel.The following Fig 4E confocal microscopy panels appear to partially overlap:The corresponding author commented that the original underlying data are no longer available due to the time since the experiments were conducted. In the absence of the underlying data, the issues with this article cannot be resolved.PLOS Biology Editors retract this article.In light of the concerns affecting multiple figure panels that question the integrity of these data, the The Fig 2F IB: pJak2Tyr1007/8 panel reports material from , publishERR, GZR, DG, AGO, MJAS, and JBCC agreed with the retraction. ERR, GZR, DG, MJAS, and AGO stand by the article\u2019s findings and apologize for the issues with the article. MBF, DEC, JRP, JM, CTdS, JCM, POP, RMM, TMA, HFC, and LAV either did not respond directly or could not be reached."}
{"text": "Scientific Reports 10.1038/srep09787, published online 10 April 2015Retraction of: The Editors have retracted this Article.1, which reports a different experiment by different authors. When asked by the Editors, the Authors were not able to provide the raw data and stated that the images in Figure\u00a03(b) were obtained through a third party hired to perform some of the experiments for this study. Given the concerns about the veracity of the data, the Editors no longer have confidence in the results and conclusions presented in this Article.After the publication, the first author reached out to the Editors to point out that that the phase contrast microscopy image in Figure\u00a03(b) appears to replicate panels that originally appeared in Figure\u00a02(b) ofAll Authors agree to this retraction."}
{"text": "Miao, J., Liu, J., Niu, J., Zhang, Y., Shen, W., Luo, C., Liu, Y., Li, C., Li, H., Yang, P., Liu, Y., Hou, F.F., Zhou, L.Wnt/\u03b2\u2010catenin/RAS signaling mediates age\u2010related renal fibrosis and is associated with mitochondrial dysfunction. Aging Cell.2019;18(5):e13004. 10.1111/acel.13004.31318148In the above published article, the authors mistakenly placed a duplicated image of PGC\u20101\u03b1 staining for the CTL and D\u2010gal/Klotho groups in Figure 5b. The corrected version of Figure 5b now contains the correct PGC\u20101\u03b1 staining images, and it is shown below.The authors would like to apologize for the inconvenience caused."}
{"text": "In \u201cUncovering Important Drivers of the Increase in the Use of Virtual Care Technologies in Nursing Care: Quantitative Analysis From the 2020 National Survey of Canadian Nurses\u201d :e33586) the authors noted one correction.In the published manuscript, the Acknowledgments read as follows:The authors would like to extend their acknowledgments to the Performance Analytics team at Canada Health Infoway for reviewing this manuscript before submission.The publication costs for this article have been covered by Canada Health Infoway Inc, a non-profit corporation funded by the Government of Canada.They have now been changed to:The authors would like to extend their acknowledgments to the Performance Analytics team at Canada Health Infoway for reviewing this manuscript before submission.The authors would like to thank the following organizations and individuals who significantly contributed to the design, implementation, distribution, dissemination, and analysis of the results of the 2020 National Survey of Canadian Nurses. The data and results from this survey served as the main source for their study: The Canadian Nurses Association (CNA); The Canadian Nursing Informatics Association (CNIA); L\u2019Association Qu\u00e9b\u00e9coise des infirmi\u00e8res et infirmiers en syst\u00e8mes et technologies de l\u2019information (AQIISTI); L\u2019Ordre des infirmi\u00e8res et infirmiers d Qu\u00e9bec (OIIQ); Glynda Rees, RN, MSN, President, Canadian Nursing Informatics Association, Faculty, BCIT School of Nursing; \u00c9ric Maillet, RN, PhD, Assistant Professor at the School of Nursing and Director of Health Informatics Programs at the University of Sherbrooke; Leanne M. Currie, RN, PhD, Associate Professor at University of British Columbia School of Nursing; Peggy White, former CNIA president; and Josette Roussel, RN, MSc (Nursing), MEd, former Executive Advisor at the Canadian Nurses Association.The publication costs for this article have been covered by Canada Health Infoway Inc, a non-profit corporation funded by the Government of Canada.The correction will appear in the online version of the paper on the JMIR Publications website on October 13, 2023 together with the publication of this correction notice. Because this was made after submission to PubMed, PubMed Central, and other full-text repositories, the corrected article has also been resubmitted to those repositories."}
{"text": "Retraction Note: BMC Pharmacology and Toxicology (2022) 23:410.1186/s40360-021-00546-2The Editor has retracted this article. After publication, concerns were raised regarding image similarities and irregular features in the presented figures. Specifically:Fig.\u00a02d appears to contain highly similar areas, and an unusual diagonal artifact that appears to duplicate nearby features of the image.Fig.\u00a02e appears to contain highly similar areas within the image.Fig.\u00a03a and b appear to overlap.Fig.\u00a05a and b appear highly similar, with some minor differences.Fig.\u00a08b appears to contain highly similar areas within image.Fig.\u00a010a appears to contain unusual features in the image.The Editor therefore no longer has confidence in the presented data.Noha Esmael Ebrahem, Eman S. Shaltout, Wael M. A. Abd El-Ghani, Noha A. Rashed, Asmaa M. Hasan, Omnia I. Ismail, Ahmed Mohamed Mohamed Mahmoud and Nora Z. Abdellah do not agree to this retraction. Diab F. Hetta and Lobna A. Abdelzaher has not responded to any correspondence from the editor or publisher about this retraction."}
{"text": "The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "There was an error in Equation 1) in the original publication . Furthermore, most events occur in the solid states, such as CT and CC transport, and, therefore, JSC must also strongly depend on their molecular morphology [5]. Nevertheless, this spectral extension is achieved by using noble NFA materials coupled with suitable polymers as a bulk heterojunction (BHJ) active layer. The benefits of NFA systems are clearly recognized by comparing with solar cells that comprise fullerene derivatives and, for instance, narrow bandgap polymers [6] or polythiophene derivatives [7].\u201d\u201cRecently, non-fullerene type acceptors (NFA) have gathered remarkable attention owing to the rapid increase in their photovoltaic power conversion efficiency (PCE) [1\u20133]. One of the most important reasons for the impressive PCE improvement must be the extended absorption spectral range, which can provide higher short circuit current densities (JThe authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "Scientific Reportshttps://doi.org/10.1038/srep19261, published online 14 January 2016Retraction of: The Editors have retracted this article.Initial concerns were raised about the fact that the tumours in Fig.\u00a06A appear to have been pasted into the image individually, as well as a partial overlap between 5367 and 5367-Vector in Fig.\u00a06C.Additionally, in Fig.\u00a05A, the mock and vector panels for t24 appear to be very similar. The journal requested raw data and evidence of ethics approval, however the information provided by the Authors was not satisfactory. As a result, the Editors lost confidence in the integrity of this article\u2019s findings.Zhe Zhang disagrees with this retraction. Guojun Zhang, Chuize Kong, Bo Zhan, Xiao Dong and Xiaojun Man did not respond to the correspondence about this retraction."}
{"text": "Similarly, there was a gene-specific pattern when comparing PBMC DNA and PL \u2013 partial compartmentalisation in env was observed for five of six participants and in gag for only three of nine participants.When comparing the LN DNA and PL compartments, a gene-specific pattern was observed - partial compartmentalisation was observed in The authors would like to apologise for any inconvenience caused."}
{"text": "In \u201cExploring an Innovative Care Model and Telemonitoring for the Management of Patients with Complex Chronic Needs: Qualitative Description Study\u201d :e15691), the authors made one addition.An Acknowledgments section has been added that reads as follows:This research was made possible by the funding support from a Canadian Institutes of Health Research Personalized Health Catalyst Grant (Funding Reference Number 155443).The correction will appear in the online version of the paper on the JMIR Publications website on October 25, 2023 together with the publication of this correction notice. Because this was made after submission to PubMed, PubMed Central, and other full-text repositories, the corrected article has also been resubmitted to those repositories."}
{"text": "Following the publication of this article , concernThe P21 western blot panel in Fig 4A appears to have no detectable signal or background, nor does the panel present a positive control to confirm a successful blot.The Ad5/F35-siAPE1 panel in Fig 8A appears to partially overlap with the Ad5/F35-siAPE1+IR panel in Fig 8a and the Ad5/F35-siAPE1+IR panel in Fig 9a despite representing different experimental conditions.The Ad5/F35-siAPE1 panel in Fig 9A appears to partially overlap with the Ad5/F35-EGFP+IR panel when rotated despite representing different experimental conditions.The authors did not provide a response to the concern regarding the P21 western blot in Fig 4A nor was any underlying data provided to resolve this issue.The authors stated that the concerns related to Figs 8 and 9 were unintentional errors made during preparation of the figures but stated they were unable to source the original underlying data for both figures. The PLOS Editors remain concerned about the reliability of these figures.PLOS ONE Editors retract this article.In light of the concerns affecting multiple figure panels that question the reliability and validity of these data, the All authors either did not respond directly to the final editorial decision or could not be reached."}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a satisfactory reply. The Editor apologizes to the readership for any inconvenience caused.Owing to the fact that the contentious data in the above article had already been published prior to its submission to"}
{"text": "The last two authors, Justine I. Davies and Lisa R. Hirschhorn, should be noted as joint senior authors of this work."}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editor's attention by a concerned reader that the tumour images shown in Fig. 3B were strikingly similar to data appearing in different form in another article written by different authors at different research institutes. Owing to the fact that the contentious data in the above article were already under consideration for publication prior to its submission to"}
{"text": "In addition, certain of the caspase-8 data shown in Fig. 1D on p. 3825 and in Fig. 2B appeared strikingly to be similar, again with the apparent horizontal flipping of the bands shown in adjacent lanes within Fig. 1D itself.Oncology Letters has decided that this paper should be retracted from the Journal on account of a lack of confidence in the presented data. The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a satisfactory reply. The Editor apologizes to the readership for any inconvenience caused.After having conducted an independent investigation of these figures in the Editorial Office, the Editor of"}
{"text": "Sergei Krivonogov was not included as an author in the original publication . The corAuthor Contributions: Conceptualization S.K., A.S. and A.M.; methodology, A.M. and A.S.; software, D.Z.; validation, D.Z., A.M. and A.S.; formal analysis, A.S.; investigation, A.M. and D.Z.; resources, S.K. and A.M.; data curation, D.Z.; writing\u2014original draft preparation, D.Z., A.S. and A.M.; writing\u2014review and editing, S.K., D.Z. and A.S.; visualization, D.Z. and A.M.; supervision, S.K. and A.S.; project administration, S.K.; funding acquisition, S.K. All authors have read and agreed to the published version of the manuscript.In the published publication , there wIn the original publication , the funFunding: This research was funded by RFBR-NSFC grant 21-55-53037 and state assignments from The Ministry of Science and Higher Education of the Russian Federation (#AAAA-A16-11611091001 and 0330-2016-0011) and performed using the equipment of the Core Facilities Center of IPCE RAS (CKP FMI IPCE RAS) and the Analytical Center for Multi-element and Isotope Studies of the V.S. Sobolev Institute of Geology and Mineralogy (Novosibirsk). Work was done on state assignment of V.S. Sobolev Institute of Geology and Mineralogy Siberian Branch Russian Academy of Sciences, Project N 122041400193-7.We changed the acknowledgements accordingly:Acknowledgments: The authors are grateful to Rysbek Satylkanov, of the Tien Shan High Mountain Scientific Centre National Academy of Sciences of the Kyrgyz Republic, for hosting our field work. We thank Nadezhda Popova and Denis Sobolev for their laboratory assistance.The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "Following publication, concerns were raised regarding the validity of the data in the article. The authors failed to provide the raw data and a satisfactory explanation during the investigation, which was conducted in accordance with Frontiers\u2019 policies. Given the concerns about the validity of the data, and the lack of raw data, the editors no longer have confidence in the findings presented in the article. This retraction was approved by the Chief Editors of Frontiers in Oncology.The authors did not agree with the retraction."}
{"text": "Moreover, various of the western blotting data shown in these figures were strikingly similar to data that had already been published in different form in other articles written by (largely) different authors at different research institutes.Molecular Medicine Reports, and due to the number of apparent duplications of strikingly similar data between Figs. 3 and 4, the Editor has decided that this paper should be retracted from the Journal. The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a satisfactory reply. The Editor apologizes to the readership for any inconvenience caused.Owing to the fact that the contentious data in the above article had already been published prior to its submission to"}
{"text": "In the original publication , specifiWe also highlighted the changes in Section 2.9. In Vivo Assessment, paragraph 1, lines 2\u20134, as well as in the Institutional Review Board Statement, with the following text.\u201cThe in vivo experiment was performed after receiving the approval from the Institutional Animal Care and Use Committee (ARC-IACUC), Cairo, Egypt (protocol number: ARC-AH-22-29)\u201dInstitutional Review Board Statement: The in vivo experiment was performed after receiving the approval from the Institutional Animal Care and Use committee (ARC-IACUC), Cairo, Egypt (Protocol number: ARC-AH-22-29) that complies with the United Kingdom Animals Scientific Procedures Act, 1986, and the European Union directive 2010/63/EU for animal experiments, as well as the ARRIVE guidelines.\u201d\u201cThe authors apologize for any inconvenience caused and the state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "Readers have raised concerns about quantitative results published in bar graphs in Figs 2\u20133, S3-S7, and S9 of this article , 2. SpecAlso, in Figs 2A, 2B, 2C, S3A, S3B, S3C, S3D, S5B, S5C, and S6B, some data annotations  on the graphs do not agree with bars\u2019 alignment with values on the Y axis. The authors stated that the data annotations within the graphs  provide the correct results.6 for stained population size and the Y axis for Fig S5C should be labelled, \u2018Absolute number of dead cells (x 106)\u2019.In addition, in Fig S5C, the data values on top of the bars are tenfold higher than the scale on the Y axis. The authors stated that the measured population size was 10The authors stand by the results and commented that these issues are due to the method(s) used to prepare the graphs. They stated that they used an early illustrator program into which they copied the values of calculated results (means and standard deviations) of three independent experiments for plotting on electronic millimeter grid paper .The authors stated that the original raw data underlying the graphs of concern are not fully available at this time given the time elapsed. In light of this issue, PLOS has been unable to verify the results and the article does not currently comply in full with the applicable version of the PLOS Data Availability policy*. Nevertheless, the editors consider that the explanation provided by the authors sufficiently clarifies how the graphs were generated.The PLOS Data Availability policy was updated in 2014. The former policy (which was in place in 2008\u201309, [.*"}
{"text": "Hancock  RSC Advances article due to a series of errors. These are:We, the named authors, hereby wholly retract this \u2022 A typo in eqn (2) that omits the minus sign in the second term of the denominator. The equation describes the extrapolation of Coupled Cluster Singles (CCS) excited-state total energies to the complete basis set (CBS) limit. Note that this does not affect any of the published CCS/CBS numbers, which were obtained correctly.\u2022 An incorrect description of how the excited-state electron-correlation energy was determined for use in the CBS extrapolations of SCS-CC2 and CCSDR(3); note that the actual extrapolations were carried out correctly.\u2022 A typo in the SCS-CC2/CBS reference dissociation energy for the pyrene dimer, which impacts all benchmarking results involving this system.\u2022 Results for all self-defined global-hybrid functionals used in our exploration of Fock exchange (FE) effects and PBE38 in the benchmarking study. This impacts the discussion of the FE study.\u2022 Results for B2GP-PLYP-D4 due to incorrect s6 implementation in the old version (2.0) of the dftd4 program used in our work, which we were not aware of.https://doi.org/10.1039/D3RA07381E.None of our major conclusions, insights and recommendations are affected, but numerical results are. Having consulted with an independent expert, the Royal Society of Chemistry has determined that any changes made to the paper to correct this would be major, and therefore that the best course of action is retraction and republication of the article with the correct data. The Royal Society of Chemistry is happy that the overall conclusions of the paper are not affected by these errors, and therefore that republication of the work with the correct data is appropriate. The republished article was peer reviewed and can be found at We, the authors, brought this matter to the attention of the Royal Society of Chemistry ourselves, and are happy with the decision to retract and republish this article.Signed: Amy C. Hancock and Lars Goerigk, 23rd November 2023RSC AdvancesRetraction endorsed by Laura Fisher, Executive Editor,"}
{"text": "There were errors in the original publication , regardiThe authors wish to change the stated concentrations: 156.25, 312.5, 625, 1250, 5000 and 10,000 \u03bcg/mL. The correct concentrations are: 31.25, 62.5, 125, 250, 500 and 1000 \u03bcg/mL. A correction has been made to Section 4.3.2 (MTT Assay), paragraph number 1.Regarding Figure 4, the authors wish to change the concentration values on the x-axes of both subfigures (A) and (B). The concentration values on the x-axes 10,000, 5000, 2500, 1250, 625 and 312.5 are corrected to 1000, 500, 250, 125, 62.5 and 31.25, and the corrected The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "The authors  agree wi"}
{"text": "This article has been retracted: Oncotarget is retracting this article at the request of the authors. The accuracy and authenticity of the data need further analysis. Figure 2 contains incorrect flow cytometry images, and Figures 1 and 3 contain inaccurate data based on flawed patient criteria. As a result, the conclusions of this paper can no longer be verified. All authors, as well as the oversight committee of Tianjin Medical University, have agreed to the retraction of this paper.73774-73786. https://doi.org/10.18632/oncotarget.17908Original article: Oncotarget. 2017; 8:73774\u201373786."}
{"text": "Retraction Note: BMC Genomics20, 795 (2019).10.1186/s12864-019-6178-zThe Editor has retracted this article. Concerns were raised regarding a number of figures, specifically:Plant, Cell & Environment [1].The WT specimen depicted in Fig.\u00a04A appears to overlap with the Col-0 specimen under drought conditions shown in Fig.\u00a04C in BMC Plant Biology paper [2].The TaGAPC1P-3/TaWRKY40 panel in Fig.\u00a06C appears to overlap with the TaGAPCp3P-3/TaMyb panel of Fig.\u00a09B in the BMC Plant Biology paper [2].Figure\u00a02A  appears to overlap with Fig.\u00a05A  of their BMC Genomics paper appears to overlap with Fig.\u00a05A  of their BMC Plant Biology paper [2].Figure\u00a02A  in their The Editor therefore no longer has confidence in the results and conclusions of this article.The authors have not responded to correspondence regarding this retraction.Plant Cell Environ. 2020; 43: 836\u2013 853. 10.1111/pce.13710.[1] Zhang, L, Lei, D, Deng, X, Li, F, Ji, H, Yang, S. Retracted: Cytosolic glyceraldehyde-3-phosphate dehydrogenase 2/5/6 increase drought tolerance via stomatal movement and reactive oxygen species scavenging in wheat. Ta_MYB in the _GAPCp2/3 promoters are involved in the drought stress response in wheat. BMC Plant Biol19, 366 (2019). 10.1186/s12870-019-1948-y.[2] Zhang, L., Song, Z., Li, F. et al. RETRACTED ARTICLE: The specific MYB binding sites bound by"}
{"text": "The authors regret\u00a0<\u00a0The authors regret Fig. 4A of the original manuscript was incorrect. I would appreciate if you would accept to replace by the corrected Fig. 4A.The authors would like to apologise for any inconvenience caused."}
{"text": "Cell Death and Disease 10.1038/s41419-020-2695-6, published online 06 July 2020Retraction to: Figure 2d: the TUNEL shNC panel for CNE2 appears to partially overlap with the yH2AX shRKIP+shNRF2 panel for CNE2Figure 2: the TUNEL shRKIP panel for CNE2 appears to partially overlap with the yH2AX shRKIP panel for CNE2Figure 6a: the NRF2 Radioresistant NPC panel appears to be partially overlap with the phosphoStat3 panel in Figure 1A in a previously published article by different authors [1]The Editors-in-Chief have retracted this article at the request of the corresponding author. Concerns were raised regarding a number of figures, specifically:The Editors-in-Chief therefore no longer have confidence in the results and conclusions of this article.The corresponding author has stated on behalf of all authors that they agree with this retraction."}
{"text": "British Journal of Surgery, 2022;, znac302, https://doi.org/10.1093/bjs/znac302This is an erratum to: Eva B Deerenberg, Nadia A Henriksen, George A Antoniou, Stavros A Antoniou, Wichor M Bramer, John P Fischer, Rene H Fortelny, Hakan G\u00f6k, Hobart W Harris, William Hope, Charlotte M Horne, Thomas K Jensen, Ferdinand K\u00f6ckerling, Alexander Kretschmer, Manuel L\u00f3pez-Cano, Flavio Malcher, Jenny M Shao, Juliette C Slieker, Gijs H J de Smet, Cesare Stabilini, Jared Torkington, Filip E Muysoms, Updated guideline for closure of abdominal wall incisions from the European and American Hernia Societies, In the originally published version, affiliations of some of the authors were incorrect in the HTML version. All affiliations in the PDF version were correct.These errors have now been corrected."}
{"text": "Retraction Note: Allergy, Asthma & Clinical Immunology (2021) 17:2410.1186/s13223-021-00527-4The Editor in Chief has retracted this article because of multiple overlaps between panels in Figs.\u00a05a and c and 6d of the article and those in rows p-STAT3, HIF-1a and Cyclin D1 of Fig.\u00a05 in a previously-published paper by different authors ["}
{"text": "The journal retracts the 2022 article cited above.Following publication, concerns were raised regarding the contributions of the authors of the article. Our investigation, conducted in accordance with Frontiers policies, confirmed a serious breach of our authorship policies and of publication ethics; the article is therefore retracted.This retraction was approved by the Chief Editors of Frontiers in Bioengineering & Biotechnology and the Chief Executive Editor of Frontiers. The authors have not responded to correspondence regarding this retraction."}
{"text": "Conserv Physiol 10(1): coad047; doi: 10.1093/conphys/coad047In the originally published version of this manuscript, the Funding section was given as follows:This work was supported by the strategic Project MARE/UIDB/MAR/04292/2020 and the Project NextGen (PTDC/CTAAMB/31532/2017), co-financed by Science and Technology Foundation through national funds, and by the European Union through FEDER  and Diversiaqua II (Mar2020-P02M01-0656P).The Funding section has been corrected to read as follows:The authors acknowledge the European Regional Development Fund (FEDER) through the Lisbon's Regional Operational Programme (LISBOA-01-0145-FEDER-031532) and the Portuguese Foundation for Science & Technology (FCT) through the project NextGen (PTDC/CTA-AMB/31532/2017) and the strategic project MARE-UIDB/04292/2020 granted to MARE . The authors also acknowledge DiversiaquaII (Mar2020-P02M01-0656P)."}
{"text": "Moreover, certain of the western blotting data shown internally within Fig. 4E and F appeared to be strikingly similar, even though the experiments portrayed in these Figure parts were intended to show the results obtained from different cell lines.Molecular Medicine Reports, and based on an overall lack in the confidence in the data, the Editor has decided that this paper should be retracted from the Journal. The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Owing to the fact that the contentious data in the above article were already under consideration for publication, or had already been published, prior to its submission to"}
{"text": "The authors regret errors in the list of co-authors, in the data and corresponding text for Hongshuai Hou and Xiaobo Ji wish to be removed from the authorship of this paper. The experiments, data compilation and writing of this article were carried out by the first author Hongliang Li and the corresponding author Mingxiang Deng, and the article was submitted by Hongliang Li. And they erroneously listed Xiaobo Ji and Hongshuai Hou as co-authors. Xiaobo Ji and Hongshuai Hou only provided some instruments and consumables for the experiments in this paper, so Xiaobo Ji and Hongshuai Hou do not feel their contribution is sufficient to be authors on this paper, and they request to update the authorship of this article to remove Hongshuai Hou and Xiaobo Ji as authors of this paper. The correct authorship is presented herein.The following sentence should be included in the acknowledgements: \u2018The authors thank Hongshuai Hou and Xiaobo Ji for providing experimental equipment and resources.\u2019The authors regret that the images provided for 2S3in the G/Sb2S3 composite was determined to be 66.68 wt%.\u201d in the original article should be corrected as \u201cFinally, the content of Sb2S3 in the G/Sb2S3 composite was determined to be 74.68 wt%.\u201dThe corresponding text \u201cFinally, the content of Sb2S3 composites delivered the average reversible capacities of 642.3, 507.6, 392.1 and 264.9 mA h g\u22121\u201d in the original article should be corrected as \u201cThe G/Sb2S3 composites delivered the average reversible capacities of 544.9, 497.6, 474.5 and 407.0 mA h g\u22121\u201d.The corresponding text \u201cThe G/Sb2S3 composites could recover to 595 mA h g\u22121 after 20 cycles\u201d in the original article should be corrected as \u201cthe average reversible capacity of the G/Sb2S3 composites could recover to 576.7 mA h g\u22121 after 20 cycles\u201d.The corresponding text \u201cthe average reversible capacity of the G/Sb\u22121 with the capacity retention of 82.9%.\u201d in the original article should be corrected as \u201cAfter 75 cycles, the reversible capacity was 365.0 mA h g\u22121 with the capacity retention of 67%.\u201dThe corresponding text \u201cAfter 75 cycles, the reversible capacity was 422 mA h gRSC Advances1 paper, published at nearly the same time, which should have been cited in this RSC Advances paper.The authors wish to draw the readers\u2019 attention to their closely related Fig. 1\u20135 were re-used in part from ref. 2S3 and stibnite. (b) TGA curves of G/Sb2S3 and stibnite. (c) Raman spectra of G/Sb2S3 and stibnite. (d) Raman spectra of Sb\u2013S. Reproduced in part from Mingxiang Deng et al., RSC Adv., 2019, 9, 15210\u201315216.1Fig. 1 (a) XRD patterns of G/Sb2S3 and stibnite. The corresponding high-resolution spectra of Sb (b), S (c) and C (d). Reproduced in part from Mingxiang Deng et al., RSC Adv., 2019, 9, 15210\u201315216.1Fig. 2 (a) XPS survey of G/Sb2S3 composites. (g and h) TEM image of the G/Sb2S3 composites. (i) HR-TEM image of the G/Sb2S3 composites. Reproduced in part from Mingxiang Deng et al., RSC Adv., 2019, 9, 15210\u201315216.1Fig. 3 (a and b) SEM image of stibnite. (c\u2013f) SEM image of the G/Sb2S3 composites, (b) stibnite. (c) Galvanostatic discharge/charge curves of G/Sb2S3 composites. (d) Cycling performance and coulombic efficiencies of G/Sb2S3 and stibnite. Reproduced in part from Mingxiang Deng et al., RSC Adv., 2019, 9, 15210\u201315216.1Fig. 4 Cyclic voltammograms of initial three cycles of (a) G/Sb2S3 electrode. (b) Nyquist plots of G/Sb2S3 and stibnite at the initial state. (c) Nyquist plots of G/Sb2S3 at different states. Reproduced in part from Mingxiang Deng et al., RSC Adv., 2019, 9, 15210\u201315216.1Fig. 5 (a) Rate performance of the SbThe Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Retraction Note: BMC Complement Med Ther 20, 347 (2020)https://doi.org/10.1186/s12906-020-03090-4The Editor has retracted this article. After publication, concerns were raised regarding the western blot images. Specifically:In Fig.\u00a06, the blots representing p38 and p-p38 appear highly similar.In the Supplementary materials, the raw data provided for the blots presented in Figs. 5 and 6 appear to contain straight-line breaks and repetitive patterns in the backgrounds.Additionally, there appear to be irregularities in the chromatogram traces presented in Fig.\u00a01.The authors have provided a replacement blot for p38 and stated that the image irregularities were caused by technical problems. However, further raw data provided by the authors appear different from the published versions of the figures and Supplementary materials. The Editor therefore no longer has confidence in the presented data.Shuang Wu has stated on behalf of all co-authors that they agree to this retraction."}
{"text": "There was an error in the original publication . In the A correction has been made to the Results Section, Paragraph 1:In 2021, COVID-19 incidence in northwest Russia varied in waves, ranging from 258.8 (per 100 K/month) in April to 1185.8 in November. At the same time, increases in incidence with the achievement of local maxima were recorded in January (1113.5 per 100 K/month), June (822.3 per 100 K/month), and November (1185.8 per 100 K/month) .The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "Retraction Note: J Exp Clin Cancer Res39, 225 (2020)10.1186/s13046-020-01704-wThe authors have retracted this article because the Western blot data presented in a number of the figures are unreliable. Longgang Wang, Jinxiang Guo, Xiuwen Kang and Lei Zhou agree with this retraction. Dongyang Wang has not responded to correspondence from the Publisher about this retraction. Jin Zhou has stated that she was not involved in the preparation and handling of this manuscript, she was not informed about its publication, and she did not grant permission for the use of her name and affiliation in this article."}
{"text": "Retraction Note: BMC Complement Med Ther 14, 380 (2014)10.1186/1472-6882-14-380Yukyung Karne is specific to ovarian cancer. Due to the cell line issue, the Editor no longer has confidence in the conclusions of this article.The Editor has retracted this article. After publication, concerns were raised regarding similar western blot control images in this article and the authors\u2019 later work . The autNone of the authors agree to this retraction."}
{"text": "In their paper \u201cChallenges with international medical graduate selection: finding positive attributes predictive of success in family medicine residency,\u201d (BMC Prim Care 23(256):2\u20139, 2022) the authors report on their research into qualitative attributes that positively correspond to success in residency with the objective of assisting in the selection of International Medical Graduate (IMG) residents most likely to achieve success in family medicine residency. The authors found that positive predictors of IMG residents\u2019 success were: presence of a positive attitude, proficient communication skills, high level of clinical knowledge, and trainability. The authors conclude that selecting IMG residents who possess these attributes will result in residents developing increased aptitudes for patient care. A careful reading of the paper raises a number of concerns. MacFarlane (Can Med Educ J 12(4):132\u201340, 2021) points out that IMGs are already marginalized in the residency selection process. Our concern is that this paper may contribute to this marginalization through a tone of negativity or bias against IMGs and the use of biased language throughout the paper that tends to cast IMGs as being inferior and somehow less well prepared for residency than Canadian Medical Graduates (CMGs). We argue that the proposed predictors are generic and equally relevant to both CMGs and IMGs. In focusing on these predictors in IMGs specifically, the paper appears to imply, without evidence, that IMGs are inadequate in the identified areas. After reviewing the paper\u2019s references, the existing literature, and an analysis of language used, we conclude that IMGs are capable candidates for residency, and that the qualitative attributes outlined in the paper offer little utility for the selection of IMG residents relative to CMG residents. In their paper \u201cChallenges with international medical graduate selection: finding positive attributes predictive of success in family medicine residency,\u201d  the authSuggestions of a negative bias regarding IMGs begin with the title of the paper: \u201cChallenges with international medical graduate selection: finding positive attributes predictive of success in family medicine residency.\u201d Whether intentional or not, the title suggests that it is challenging to select IMGs who will be successful in family medicine residency, or to find positive attributes in IMGs that might predict their success. In support of this proposition, the authors reference Andrew  assertin\u201cInitially, the IMGs in the IMG-BC family medicine program generally performed as well as other residents in their program evaluations, but not as well in the national CFPC certification exam when compared with all BC residents across the various hospital sites. However, IMGs have progressively improved their performance and their results are now comparable with those of their Canadian-trained colleagues\u201d (pg 114).On closer examination of these supporting references, it appears that the authors have misconstrued the referenced papers\u2019 findings. Andrew reported that IMGs performed similarly to CMGs on ITERs but underperformed on CFPC examinations. It is important to note that Andrew\u2019s study which reported on IMG performance in the IMG-BC family medical program dates to 2010. Interestingly, Thomson and Cohl  reportedThe improvement was attributed to \u201ctechniques for exam success\u201d. This suggests that IMG performance on CFPC examinations is not clear cut, that there may be many factors that influence performance, including exam taking skills versus medical competence, and that performance may vary over time.With regard to the Mathews reference, nowhere in the Mathews paper can we find a reference to medical educators being concerned regarding shortcomings of IMGs on family medicine examinations. Regarding IMG success rates, Mathews and colleagues reported 78.1% of IMGs received CFPC certification (i.e. passed exams). However, their study does not compare IMG outcomes on CFPC exams with CMG outcomes, therefore there is no way to determine whether a 78.1% success rate for IMGs is better or worse than the CMG success rate. Further, the authors\u2019 analysis does not account for the fact that despite progress in examination design, exam-taking skills remain a factor that confound efforts at assessing competence. The authors\u2019 conclusion that IMGs currently struggle with performance on family medicine examinations, and the implication that this reflects on competence, is not supported by the references provided.Unfortunately, the difficulties with this paper run deeper. On page 2 of the paper, the authors note that, \u201cAn increasing percentage of IMGs have completed their medical degrees 5\u20139 years before beginning residency\u201d then go on to suggest that \u201cThis gap in training could result in reduced recency of knowledge acquired in medical school and could play a role in IMGs struggling in examinations.\u201d Entirely aside from the weakness of evidence provided by the authors to support IMGs as actually \u201cstruggling\u201d in examinations, in a careful reading of the author\u2019s own supporting reference, Mathew\u2019s and colleagues found that there was not a significant difference between recent graduates and new graduates in passing the CFPC exam. There was a significant difference between recent graduates and new graduates in passing the Medical Council of Canada Qualifying Exam 2 (MCCQE2) but one which contradicts the authors\u2019 hypothesis. In their discussion section, Mathews, et al. conclude that \u201cGiven that they have more clinical experience, it is not surprising that older graduates are more likely than their younger counterparts are to pass the MCCQE2 (an examination written after the first year of residency training); there is no difference between recent and older graduates\u2019 performance on certification  examinations.\u201c\u201cBlame for the failure of many IMGs on family medicine examinations\u201d (Pg 2) on time since graduation is not supported by their own references. Also noteworthy is the authors\u2019 use of language. The authors refer to \u201cthe failure of many IMGs,\u201d yet the authors have failed to support their proposition that \u201cmany\u201d IMGs have failed examinations. How many is \u201cmany\u201d? The choice of wording implies a serious problem with IMG performance, yet this is not established. It is the use of language like this throughout this paper that gives rise to a perception of bias and negativity regarding IMGs.Consider the following passages:\u201ccandidates can be selected that are better suited for the established education system.\u201d (Pg 2) Are the authors implying that IMGs are not well suited to the established educational system?\u201cmore robust candidates can be selected and issues can be mitigated during residency, which will lead to family medicine practitioners who can provide patient care.\u201d (Pg 2) Are the authors suggesting that IMGs are not robust candidates and that they have issues that mean they cannot provide adequate patient care?\u201cThus, if a candidate has been educated in a system that lacks adequate professionalism development, it will be challenging to institute such changes so late in training.\u201d (Pg 6) The authors appear to be arguing that international educational systems generate physicians who lack professionalism and that, further, this lack of professionalism will be \u201cchallenging\u201d to address in training. It is difficult not to see such a proposition as reflecting a negative bias against IMGs.It may be argued that the authors\u2019 key findings that residents\u2019 success is enhanced by the presence of a positive attitude, proficient communication skills, a high level of clinical knowledge, and trainability are equally relevant to CMGs or any professional. In their conclusion, the authors acknowledge that \u201cIt is evident that the competencies revealed in this study are relevant to both IMGs and CMGs\u201d yet they spend an entire paper trying to demonstrate that IMGs in particular may be challenged by inadequacies in these areas.The biased language continues throughout the authors\u2019 analysis of their four key indicators of success. With regard to trainability, the authors note that, \u201cThe attribute that most commonly associated to an IMG resident\u2019s trainability was professionalism.\u201d (Pg 3) Again, the authors appear to be implying that IMGs suffer from a lack of professionalism without offering any supporting evidence. The authors go on to further discuss professionalism stating that, \u201cunprofessional residents present a strong association to lawsuits and adverse outcomes in their later careers.\u201d (Pg 6) Such discussions in the context of a paper focusing on selection criteria for IMGs raises the spectre of IMGs as a source of unprofessional conduct, lawsuits, and adverse outcomes. Such implications can only have a negative impact on public and professional assessments of IMGs\u2019 abilities.The authors go on to link trainability with emotional intelligence, stating that, \u201cEmotional Intelligence is understood as the ability to perceive, understand, and manage emotions in oneself and others.\u201d (Pg 6) Again, in the context of a paper focused on characteristics that contribute to IMG success in residency, are the authors implying without evidence that IMGs lack emotional intelligence? The authors also highlight the ability to accept and integrate feedback as an important part of trainability. Concerningly, the authors suggest that \u201ccertain cultural norms may preclude proper assessment of this trait.\u201d (Pg 6) Such an unsupported statement linking cultural norms with an inability to accept and integrate feedback is suggestive of a perspective that IMGs raised and educated in other cultures have difficulty accepting and integrating feedback. Such a perspective is highly questionable.The above vignettes illustrate concerns regarding bias against IMGs reflected in this paper, and in at least some of the medical profession. A careful reader will notice other examples. The authors conclude that \u201cOverall the methodology of this study is sound\u201d and that, \u201cAll identified predictors were determined to correspond with IMG family medicine residents\u2019 success in residency.\u201d  With respect, we disagree that the methodology of this study is sound. Aside from the lack of specificity of these predictors to IMGs, all interviews were conducted by the same interviewer, which introduces a level of bias that is not addressed in the paper. As the author notes, there may well be a sampling bias. With only 13 of 25 preceptors approached agreeing to participate, the question arises why others were reluctant, and whether some of those who did agree to participate may have chosen to do so because they wished to articulate negative experiences with IMGs. The authors do not appear to have explored the respondents\u2019 reasons for deciding to participate in the study.Finally, in the original paper , the stuIn conclusion, the attributes identified by the authors offer little to assist in the selection of IMG family medicine residents. Further, the implications throughout this paper of IMG inadequacy are disturbing and in contradiction to existing research and literature that demonstrates that IMGs are capable residency candidates and that IMG patient outcomes are equal to or superior to those of CMGs or North American trained physicians. , 7 The a"}
{"text": "British Journal of Cancer 10.1038/s41416-020-01153-4, published online 16 November 2020Correction to: The original version of this article contained an error in an affiliation. Upon careful review of the paper, the authors noticed that the affiliation for Goran Malenkovic was not written correctly. The authors only submitted the following affiliation Gynecologic Oncology Department Clinic for Operative Oncology, Institute of Oncology of Vojvodina, Serbia but they missed to notice that the Faculty of Medicine Novi Sad, University of Novi Sad, Serbia should also be in the affiliation."}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a satisfactory reply. The Editor apologizes to the readership for any inconvenience caused.Owing to the fact that some of the data in the above article had already been published prior to its submission to"}
{"text": "Retraction Note: J Exp Clin Cancer Res 42, 14 (2023)https://doi.org/10.1186/s13046-022-02588-8The Editor-in-Chief has retracted this article. Concerns were raised regarding a number of figures, specifically:Fig. 2B: the si-2# invasion panel appears to partially overlap with si-BCAR4\u2009+\u2009miR-644a inhibitor invasion panel in Fig. 4EFig. 4E: the control panels for migration and invasion appear to overlapFig. 4E: the si-BCAR4 panels for migration and invasion appear to overlapFig. 4F: the control panels for migration and invasion appear to overlapFig. 5C: the mimic nc and inhibitor nc panels appear to overlapFig. 5C: the mimic nc and miR-644a inhibitor panels appear to overlapThe Editor-in-Chief therefore no longer has confidence in the results and conclusions of this article.Zhongxin Lu has stated on behalf of all authors that they agree to this retraction."}
{"text": "Retraction Note: BMC Med 17, 223 (2019)https://doi.org/10.1186/s12916-019-1457-8The Editor has retracted this article. After publication, concerns were raised regarding the images presented in Fig.\u00a07. Specifically:The left PHA image in Fig.\u00a07a appears highly similar to the middle PHA image in Fig.\u00a07b (rotated);All the Medium images in Fig.\u00a07a and b appear highly similar; the left and right images in Fig.\u00a07b appear to be missing some features compared with the other images.The authors have been able to provide the quantified data, but stated that the original images are no longer available. The Editor therefore no longer has confidence in the presented data.None of the authors agrees to this retraction."}
{"text": "Correction: Spine Deformity 10.1007/s43390-023-00732-8The authors of the article would like to state the following acknowledgment:"}
{"text": "Special Account for Research Grants (ELKE) of University of West Attica.'' have not been included in the Acknowledgments section of the paper. Please add the before mentioned text in the Acknowledgments section.>.The authors regret < The acknowledgments ``This study has received financial support from the The authors would like to apologise for any inconvenience caused."}
{"text": "The authors would like to make the following correction to the published paper . The chaAdd this sentence to \u201cAcknowledgement\u201d section: The authors are grateful to the Deanship of Scientific Research and King Saud University for funding made available through the Vice Deanship of Scientific Research Chair.The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "The authors have requested that this preprint be removed from Research Square."}
{"text": "The journal and Chief Editors retract the 29 November 2021 article cited above.Following publication, concerns were raised regarding abnormal similarities with the contents of other articles published by unrelated research groups. A subsequent investigation, which was conducted in accordance with Frontiers\u2019 policies, raised strong concerns over the authorship of the articles, resulting in a loss of confidence in the findings presented in the article.The authors have not responded to this retraction.This retraction was approved by the Chief Editors of Frontiers in Endocrinology and the Chief Executive Editor of Frontiers."}
{"text": "Due to a production error, the text \u201cOne of the handling editors for this special issue is DP, who is also an author of this submitted manuscript. We have therefore suggested name of other handling editor Shashi Kant Bhatia for our manuscript to avoid the conflict.\u201d was incorrectly added to the Conflict of Interest Statement. The corrected statement reads:\u201cThe authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.\u201dThe publisher apologizes for this mistake. The original article has been updated."}
{"text": "Correction to: Globalization and Health (2022) 18:8510.1186/s12992-022-00878-6Following publication of the original article [1], the authors identified errors in Table\u00a04 and in the analysis provided in Additional File 2.Concerning Table\u00a0Regarding Additional File 2, the logistic multi-level regression analyses results in this file were inconsistent with the results that are provided in Figure\u00a03. This inconsistency was the result of an error in the statistical analyses performed by the authors, whereby the authors mistakenly presented the association between the income of countries and the likelihood of specific vaccines and vaccination objectives being included in AMR plans. Additional File 2 has since been corrected in the published article.Per the correction of Additional File 2, the following corrections have been made (see the corrections highlighted in bold) in:The \u2018Country comparison\u2019 subsection of the Results:higher probability of including specific vaccines in AMR plans . We found a weaker association, non-significant as well, in the opposite direction between income and the probability of including vaccination objectives in action plans; here an increase in income is accompanied by a slightly lower probability . The multilevel model shows that regional variation is larger when it comes to the inclusion of specific vaccines in national action plans compared to objectives on vaccination (see Supplementary File 2).\u2019\u2018We assessed the association between income and vaccination using multilevel logistic regression and found that an increase of income is accompanied by a The Results section of the Abstract:lower income countries, while higher income countries more often include specific vaccines.\u2019\u2018We found indications that vaccination objectives are more often included in AMR plans from The Discussion section:less likely to include vaccination objectives in their action plans.\u2019\u2018Similarly, our review found indications of a possible association between the income level and a focus on objectives on vaccination, with HICs The original article has since been updated to correct these errors. The authors thank you for reading this erratum and apologize for any inconvenience caused.Below is the link to the electronic supplementary material.Additional File 2"}
{"text": "Additional Affiliation(s).\u201cGuihua, Jiang\u201d. In addition to affiliation(s) \u201c2 The Department of Medical Imaging, Guangdong Second Provincial General Hospital, Guangzhou 510317, China;\u201d, the updated affiliation(s) should include: \u201c1 The Second School of Clinical Medicine, Southern Medical University, Guangzhou 510515, China;\u201d. The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated.In the published publication , there w"}
{"text": "Huynh et al., RSC Adv., 2020, 10, 18423\u201318433, https://doi.org/10.1039/D0RA01750G.Retraction of \u2018New synthesis of 2-aroylbenzothiazoles  RSC Advances article due to irreproducibility of the reaction yields.Tien V. Huynh, Ngoc T. K. Luong, Duyen T. P. Nguyen, Tung T. Nguyen and Nam T. S. Phan hereby wholly retract this Khang V. Doan and Son H. Doan were informed about the retraction of the article, but have not responded to any correspondence regarding the retraction.3aa\u20133df) could not be reproduced when freshly opened reagents and solvents were used. It could be reasoned that the reported reagents were contaminated with unknown impurities, which have facilitated the reaction.The results shown in Table 2 (the synthesis of compounds The corresponding authors regret this carelessness and apologise for any inconvenience to readers.Signed: Tien V. Huynh, Khang V. Doan, Ngoc T. K. Luong, Duyen T. P. Nguyen, Son H. Doan, Tung T. Nguyen and Nam T. S. Phan.Date: 16th March 2023RSC AdvancesRetraction endorsed by Laura Fisher, Executive Editor,"}
{"text": "In \u201cEmotional Distress During COVID-19 due to Mental Health Conditions and Economic Vulnerability: Retrospective Analysis of Survey-Linked Twitter Data With a Semisupervised Machine Learning Algorithm\u201d , the authors noted one error.The title \u201cEmotional Distress During COVID-19 due to Mental Health Conditions and Economic Vulnerability: Retrospective Analysis of Survey-Linked Twitter Data With a Semisupervised Machine Learning Algorithm\u201d has been changed to \u201cEmotional Distress During COVID-19 by Mental Health Conditions and Economic Vulnerability: Retrospective Analysis of Survey-Linked Twitter Data With a Semisupervised Machine Learning Algorithm.\u201dThe correction will appear in the online version of the paper on the JMIR Publications website on March 27, 2023, together with the publication of this correction notice. Because this was made after submission to PubMed, PubMed Central, and other full-text repositories, the corrected article has also been resubmitted to those repositories."}
{"text": "Oncol Lett 20: 80, 2020].Oncology Letters, the Editor has decided that this paper should be retracted from the Journal. After having been in contact with the authors, they accepted the decision to retract the paper. The Editor apologizes to the readership for any inconvenience caused.Owing to the fact that the contentious data in Fig. 2 of the above article were already under consideration for publication prior to its submission to"}
{"text": "The authors wish to make three changes to their published paper .M was wrong, and the value of the maximum mode number N was missing. The corrected sentence is shown below:There is a mistake in Section 3, on page 4. The value of the maximum principal mode number N = 580 and the maximum principal mode number is M = N1/2 = 24 at \u03bb = 633 nm, for g = 2.0, and The maximum mode number for the GI mPOF under study is X-axis label should be m/M. The authors added \u201c\u201d in the legend for There is a mistake in Figure 2. The The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Owing to the fact that some of the data in the above article had already been published, or were under consideration for publication, prior to its submission to"}
{"text": "The authors regret to make some minor changes in the published articles particularly in the Tables. Author would like to correct abbreviations and annotations The authors would like to apologise for any inconvenience caused."}
{"text": "Retraction: Biol Res (2016) 49:24https://doi.org/10.1186/s40659-016-0084-5The Editor-in-Chief has retracted this article because it contains substantial overlap with a previously published work by the same authors . This arAuthor Md. Amirul Alam disagrees with this retraction. The other authors have not responded to correspondence regarding this retraction."}
{"text": "Cancer Medicine. 2017; 819\u2013833: The above article, published online on March 23, 2017 in Wiley Online Library (https://onlinelibrary.wiley.com/doi/10.1002/cam4.1030) has been retracted by agreement between the authors, the journal's Editor\u2010in\u2010Chief, Dr. Stephen Tait, and John Wiley & Sons Ltd.Retraction: \u2018Effects of miR\u2010145\u20105p through NRAS on the cell proliferation, apoptosis, migration, and invasion in melanoma by inhibiting MAPK and PI3K/AKT pathways,\u2019 Sha Liu, Guozhen Gao, Dexiong Yan, Xiangjun Chen, Xingwei Yao, Shuzhong Guo, Guirong Li, Yu Zhao, The retraction has been agreed following allegations raised by a third party. Multiple flaws and inconsistencies between the results presented and the experimental methods described were found, as well as instances of image manipulation across several figures. As a result, the editors consider the conclusions of this article to be invalid."}
{"text": "There was an error of omission in the original publication , in the A correction has been made to the Conflicts of Interest section. The revised text is: \u201cThe author N.N. declares no conflict of interest as an independent researcher. R.M. and S.M.-v.S. are the inventors of the DASD device, full-time staff members of the University of the Western Cape and joint patent holders with the University of the Western Cape. The DASD device was licensed for manufacture and sale to Amplitude Consulting PTY (LTD) between October 2021 and December 2022. R.M. and S.M.-v.S. are shareholders of Amplitude Consulting PTY (LTD).\u201dThe authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "Kazem Baesi), psPAX2  and pMD2.G  vectors complexed with 20 \u03bcl of TurboFect Transfection Reagent in 6-well plate  HIV-1 stocks were generated by transfection of HEK-293T cells (7 \u00d7 10Also, the authors did not include a sentence in their acknowledgements section that they wished to include. \"The authors also would like to thank Dr. Kazem Baesi of the Pasture Institute of Iran for the gift of the VSV-G-pseudotyped HIV-1 vectors used in this project"}
{"text": "Caplan, Keri Cavanaugh, Bertrand Perroud, Tadeusz Wroblewski, Richard W. Michelmore, Blake C. Meyers, The Role of TIR-NBS and TIR-X Proteins in Plant Basal Defense Responses, Plant Physiology, Volume 162, Issue 3, July 2013, Pages 1459\u20131472, The authors were made aware of the image duplicated in This correction does not otherwise affect the results nor alter any of the original conclusions. We apologize for any inconvenience to the readers."}
{"text": "The authors would like to draw the reader\u2019s attention to a YouTube video2"}
{"text": "Ibrahim, Nosiba Ibrahim Mohammed Ahmed Hamza Mohammed, Khabab Abbasher Hussien Mohamed Ahmed, Gaffar Alemam A. Manhal, Mohammed Mahmmoud Fadelallah Eljack, Muhammad Junaid Tahir, HSR21068, https://onlinelibrary.wiley.com/doi/full/10.1002/hsr2.1068} has been retracted by agreement between the journal's Editor\u2010in\u2010Chief, Charles Young and John Wiley & Sons Ltd. The retraction has been agreed given the journal has received evidence confirming that the peer review process of this paper was manipulated. As a result, the conclusions reported in the article are not considered reliable.The above article, published online on {First published: 19 January 2023} in Wiley Online Library { Ibrahim, Nosiba Ibrahim Mohammed Ahmed Hamza Mohammed, Khabab Abbasher Hussien Mohamed Ahmed, Gaffar Alemam A. Manhal, Mohammed Mahmmoud Fadelallah Eljack, Muhammad Junaid Tahir, HSR21068, https://onlinelibrary.wiley.com/doi/full/10.1002/hsr2.1068} has been retracted by agreement between the journal's Editor\u2010in\u2010Chief, Charles Young and John Wiley & Sons Ltd. The retraction has been agreed given the journal has received evidence confirming that the peer review process of this paper was manipulated. As a result, the conclusions reported in the article are not considered reliable.The above article, published online on {First published: 19 January 2023} in Wiley Online Library {"}
{"text": "Addition of an AuthorPolina M. Tyubaeva was not included as an author in the original publication [lication . The corAuthor ContributionsConceptualization, S.G.K. and I.A.V.; investigation, S.G.K., P.M.T. and I.A.V.; resources, I.A.V. and P.M.T.; data curation, A.A.O.; writing\u2014original draft preparation, S.G.K. and A.A.P.; writing\u2014review and editing, A.A.P. and I.A.V.; visualization, S.G.K.; supervision, S.G.K.; project administration, I.A.V.; funding acquisition, I.A.V. All authors have read and agreed to the published version of the manuscript."}
{"text": "The last two authors, Kriszti\u00e1n Szigeti and Domokos M\u00e1th\u00e9, should be noted as contributing equally to this work."}
{"text": "The journal retracts the 2021 article cited above.Following publication, concerns were raised regarding the contributions of the authors of the article. Our investigation, conducted in accordance with Frontiers policies, confirmed a serious breach of our authorship policies and of publication ethics; the article is therefore retracted.This retraction was approved by the Chief Editors of Frontiers in Public Health and the Chief Executive Editor of Frontiers. The authors have not responded to correspondence regarding this retraction."}
{"text": "Retraction Note: BMC Complement Med Ther 14, 243 (2014)10.1186/1472-6882-14-243The Editor has retracted this article. Concerns were raised about a number of the images presented in Figure 2, Figure 10 and Figure 11. The authors provided raw data; however, as there were inconsistencies in these data the Editor no longer has confidence in the results and conclusions presented. In addition, the authors have not provided evidence of appropriate ethical oversight of this study. Vikas Kumar disagrees with this retraction. Danish Ahmed, Amita Verma, Girja Shankar Shukla and Manju Sharma have not responded to correspondence from the Editor about this retraction."}
{"text": "The authors were asked for an explanation to account for these concerns, but the Editorial Office did not receive a reply. The Editor apologizes to the readership for any inconvenience caused.Owing to the fact that the contentious data in the above article had already been published prior to its submission to"}
{"text": "After having been in contact with the authors, they accepted the decision to retract the paper. The Editor apologizes to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editor's attention by a concerned reader that certain of the Transwell invasion assay data shown in Fig. 5E were strikingly similar to data appearing in different form in other articles written by different authors at different research institutes, several of which have already been retracted. Owing to the fact that the contentious data in the above article had already been published prior to its submission to"}
{"text": "Page 3, Fig.\u00a01: Due to incorrect labeling of electrophoresis lanes, panel A does not match its description in the figure legend. Panel A should appear as shown in this erratum. This error does not affect the original data, data interpretation, or conclusions of the article.Volume 11, no. 1, e03155-22, 2023,"}
{"text": "The retraction has been agreed following an investigation into concerns raised by a third party, which revealed inappropriate duplications of image panels within the article (multiple panels of fig. 2G and 3C), as well as inappropriate duplications of panels in figs 1D, 2G, and 3C with another study [1], which shares two of the authors. Compelling raw data was not available. Thus, the editors consider the conclusions of this manuscript substantially compromised.The above article, published online on 17 July 2020 in Wiley Online Library (10.3389/fcell.2021.568738. Front. Cell Dev. Biol., 09 February 2021.[1] Exosomal miR\u2010128\u20103p Promotes Epithelial\u2010to\u2010Mesenchymal Transition in Colorectal Cancer Cells by Targeting FOXO4 via TGF\u2010\u03b2/SMAD and JAK/STAT3 Signaling DOI:Referencehttps://doi.org/10.1002/1878-0261.127651 Zhang X, Bai J, Yin H, Long L, Zheng Z, Wang Q, et\u00a0al. Exosomal miR\u20101255b\u20105p targets human telomerase reverse transcriptase in colorectal cancer cells to suppress epithelial\u2010to\u2010mesenchymal transition. Mol Oncol. 2020;14:2589\u2013608.  The retraction has been agreed following an investigation into concerns raised by a third party, which revealed inappropriate duplications of image panels within the article (multiple panels of fig. 2G and 3C), as well as inappropriate duplications of panels in figs 1D, 2G, and 3C with another study [1], which shares two of the authors. Compelling raw data was not available. Thus, the editors consider the conclusions of this manuscript substantially compromised.The above article, published online on 17 July 2020 in Wiley Online Library (10.3389/fcell.2021.568738. Front. Cell Dev. Biol., 09 February 2021.[1] Exosomal miR\u2010128\u20103p Promotes Epithelial\u2010to\u2010Mesenchymal Transition in Colorectal Cancer Cells by Targeting FOXO4 via TGF\u2010\u03b2/SMAD and JAK/STAT3 Signaling DOI:Referencehttps://doi.org/10.1002/1878-0261.127651 Zhang X, Bai J, Yin H, Long L, Zheng Z, Wang Q, et\u00a0al. Exosomal miR\u20101255b\u20105p targets human telomerase reverse transcriptase in colorectal cancer cells to suppress epithelial\u2010to\u2010mesenchymal transition. Mol Oncol. 2020;14:2589\u2013608."}
{"text": "A Retraction of the Systematic Review ArticleOpen resection compared to mini-invasive in colorectal cancer and liver metastases: a meta-analysis By Gong J, Gao F, Xie Q, Zhao X and Lei Z. (2021) Front. Surg. 8:726217. doi: 10.3389/fsurg.2021.726217The journal and Chief Editors retract the 30 August 2021 article cited above.Following publication, concerns were raised regarding abnormal similarities with the contents of other articles published by unrelated research groups. A subsequent investigation, which was conducted in accordance with Frontiers' policies, raised strong concerns over the authorship of the articles, resulting in a loss of confidence in the findings presented in the article.The authors have not responded to this retraction.This retraction was approved by the Chief Editors of Frontiers in Surgery and the Chief Executive Editor of Frontiers."}
{"text": "The authors wish to make the following corrections to this paper :In the last paragraph of Section 9, Immune Mechanisms and Induction of Ant-Ganglioside Antibodies, the author mistakenly wrote: \u201cAs an example, Hirano and colleagues [84] reported on a family with Cj infection, in which IgG but IgM anti-ganglioside antibodies were associated with GBS.\u201d The correct version should be as follows: \u201cAs an example, Rees and colleagues [39] reported that some patients with uncomplicated Cj infection without neuropathy developed IgM but not IgG anti-ganglioside antibodies.\u201dThe authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. The original publication has also been updated."}
{"text": "This article has been retracted: Due to defects in the experimental results and methods, the conclusions of this paper are invalid. The authors were unable to verify or replicate the experiments. As a result, with the agreement of all authors, Oncotarget has decided to retract this paper.109238-109246. https://doi.org/10.18632/oncotarget.22652Original article: Oncotarget. 2017; 8:109238\u2013109246."}
{"text": "When this article was originally published in Psychological Medicine it included the sentence \u2018'Women's stomachs are on average less acidic compared to men's and this increases the absorption of antipsychotic drugs\u2019. Based on the available literature on this topic, it is difficult to determine whether, and to what extent, sex differences in stomach acidity influence the absorption of antipsychotics. Due to this, this sentence has been removed and Figure 1 has been updated to reflect this change.The authors apologise for this error."}
{"text": "Following the publication of this article , concernThe Fig 1A OPM-2 actin panel and the Fig 1C PT#4 actin panel appear similar when horizontally stretched despite representing different experimental conditions.Lanes 2\u20134 of the Fig 1A ANBL6/U266/8226 actin panel appear similar to the Fig 3A shRNA MNK2 GAPDH panel.The Fig 1C PT#2 P-MNK and T-MNK panels of [In Fig 1D, the MNK1 panel in the MNK2 immunoprecipitation blot has no detectable signal nor does the panel present a positive control to confirm a successful blot.The authors did not provide the raw data underlying the published results for editorial review. In the absence of the raw data required to support the published results PLOS is unable to resolve the above issues.PLOS ONE Editors retract this article.In light of the concerns affecting multiple figure panels that question the validity and reliability of these data, the CB and JG agreed with the retraction. PF did not agree with the retraction. YS, BH, YY, and AL either did not respond directly or could not be reached."}
{"text": "Retraction note: Mol Cancer 18, 185 (2019)10.1186/s12943-019-1116-xThe Editor in Chief has retracted this article after concerns were raised about potential image overlap in Figs.\u00a01 and 6. Therefore, the Editor has lost confidence in the data presented here. None of the authors has responded to any correspondence from the editor/publisher about this retraction.Partial image overlap between Fig.\u00a01A specifically the upper image for shCtrl with Fig.\u00a01J specifically the upper image for LGR5+.Image overlap between Fig.\u00a01H specifically cells at position 2 in 3rd lane for shCBX8-2 with Fig.\u00a02G specifically cells at position 1 in 5th lane for vec\u2009+\u2009CPT-11.Image overlap between Fig.\u00a06F specifically the last lane of WB for \u00df-actin with Fig.\u00a05A of .Image overlap between Fig.\u00a01I specifically the last lane for shCBX8-2 with Fig.\u00a04H of [Image overlap between Fig.\u00a01I specifically the last lane for shCBX8-2 with Fig.\u00a08A of .Image overlap between Fig.\u00a01I specifically the last lane for shCBX8-2 with Fig.\u00a08A of ."}
{"text": "Biol. Open (2017) 6, 489-495 (doi:10.1242/bio.024133).There are potential issues in Fig 4 in In Fig 4B, it appears there is background duplication in the NC and 80\u03bcM Tan IIA+ox-LDL panels, and also in the ox-LDL and 40\u03bcM Tan IIA+ox-LDL panels.We have made multiple attempts to contact all authors to request original data for the affected figures but have not received a response. Therefore, the journal is publishing this note to alert readers to our concerns."}
{"text": "This paper provides a reinterpretation of some of the most influential skeptical arguments, Agrippa\u2019s trilemma, meta-regress arguments, and Cartesian external world skepticism. These skeptical arguments are reasonably regarded as unsound arguments about the extent of our knowledge. However, reinterpretations of these arguments tell us something significant about the preconditions and limits of persuasive argumentation. These results contribute to the ongoing debates about the nature and resolvability of deep disagreement. The variety of skeptical arguments shows that we must distinguish different types of deep disagreement. Moreover, the reinterpretation of skeptical arguments elucidates that deep disagreement cannot be resolved via argumentation. Typically, epistemologists identify two desiderata concerning skeptical arguments, explaining how the skeptical intuition arises and showing why the skeptical argument is unsound (or why it is sound). Most epistemologists do not regard skeptical arguments as convincing. In particular, they do not find regress arguments cogent, and consequently, they reject them as arguments about the limits of knowledge. In discussions of skeptical arguments, it is occasionally pointed out that we are not in a position to present a persuasive argument to the skeptic but that this does not imply that we cannot know.Argumentation might seem a rather neglected phenomenon in contemporary epistemology, despite the raising popularity of social epistemology, but this impression is not entirely correct, given the substantial recent literature on argumentation in epistemology.Agrippa\u2019s trilemmaA meta-regress argumentThe argument for external world skepticism, including the claim that Moorean reasoning is epistemically defective because it cannot offer a persuasive argument to the skeptic.This list of skeptical arguments is, of course, not exhaustive. For example, there are other explanations on the market of why Moorean reasoning is epistemically defective.In this paper, I will investigate two argumentative phenomena\u2014argumentation with a skeptic (instead of argumentation for or against skepticism) and deep disagreement. I will focus on the following three skeptical arguments:q requires justification via another proposition p which itself has to be justified and so on. (A2), in comparison, relies on the assumption that in order to know (or be justified to believe) that q on the basis of p, S needs to know (or be justified to believe) that p properly supports q. Note that there are not only structural similarities between (A1) and (A2). Carroll  can be transformed into an argument that is at least close to (A1). However, I do not see how (A1) could be formulated as a version of (A2). Furthermore, I think there is an intuitive difference between requiring an argument for every premise used and requiring an argument for the adequacy of every argument presented. People often require further information about the premises of an argument, but asking for a meta-argument seems intuitively a different issue.7Before proceeding, let me pause for a moment to say a few words about the structure of the skeptical arguments that will be analyzed. (A1) and (A2) are regress arguments, i.e. they rely on a regress clause which implies that one has to undergo infinitely many steps for achieving justification and/or knowledge, a requirement that cannot be fulfilled. (A1) is based on the idea that justification or knowledge of  Carroll  presentsMoreover, argument (A3) concerning Moorean reasoning and bootstrapping can also be interpreted as a regress problem. If S cannot come to know that a source is reliable via information delivered from the source itself, then S needs a second source for determining the reliability of the source and so on. Hence, an infinite regress threatens. However, this interpretation of (A3) ignores that there remains a puzzle about why bootstrapping and Moorean reasoning are or seem implausible, given that one rejects this kind of regress. Hence, all three arguments (A1)\u2013(A3) are presumably interpretable as regress-arguments. Nevertheless, there are notable differences between these arguments, which are also crucial for revealing different types of deep disagreement. For these reasons, I will stick hereinafter to the useful distinction between (A1), (A2) and (A3).8p and B rejects that p or suspends judgment about p.p end up having the same doxastic attitude. One intuitive way of resolving disagreement is via persuasion. Hereinafter, I understand persuasion in the following sense:Definition: Persuasionp via action c iff A performs c and B believes that p because of c.10A persuades B that Persuasion is an instance of resolving disagreement given that one party who believes that p makes another party also believe that p. This is the instance of resolving disagreement on which I will focus in this paper. Moreover, disagreement can be resolved via various methods, e.g. via demonstration. One paradigmatic way of resolving disagreement, which is subject of this paper, is via argumentation.Let me start with some remarks about disagreement in general. Two parties disagree about a target proposition if they have different doxastic attitudes towards this proposition, i.e. if A believes that deep disagreement. In his seminal paper, Fogelin foundationalist justification(ii)circular justification(iii)infinite justificationThere are exactly three potential alternatives of justification for believing that p.None of these three alternatives can yield justification for believing that There is no knowledge without justification.Therefore, we do not have any knowledge.There is wide agreement in contemporary epistemology that the skeptical argument based on Agrippa\u2019s trilemma is unsound since (2) is false because either (i), (ii), or (iii) can yield justification. Foundationalism accepts (i), coherentism (ii), and infinitism (iii) as a way of acquiring justification.16The first skeptical argument, discussed here, is Agrippa\u2019s trilemma.Agrippa\u2019s trilemma states that a subject is, under certain circumstances, forced to either reason ad infinitum, to stop at an arbitrary point, or to undergo circular reasoning. However, when would a subject face a trilemma of presenting new reasons ad infinitum, stopping at an arbitrary point, or reasoning circularly if not in cases of justification? The answer can be found in the context of argumentation, or so I will argue.17p simply by uttering that p, without providing any further evidence for p.Definition: Persuasion via Trustp iff A utters that p and B believes that p because of A\u2019s utterance that p.20A persuades B via trust that Persuasion via trust does not require that B reflectively believes that A is reliable or trustworthy concerning p. It can also happen rather automatically, for example, if a child automatically believes her parents without entertaining any thought about their reliability or trustworthiness. Hence, persuasion via trust often only involves the absence of a negative belief that the speaker is unreliable or lacks trustworthiness. For the purpose of this paper, I am particularly interested in persuasion via argumentation in the following sense:Definition: Persuasion via Argumentationp iff A presents an argumentation for p and B believes that p because of this argumentation.21A persuades B via argumentation that Arguments consist of one or more premises and a conclusion.PCBc because of A\u2019s argumentation consisting of premises p1\u2026pn and conclusion c, only if B believes sufficiently many of premises p1\u2026pn.B believes that I will call hearers who follow PCB unprejudiced, since they do not believe the conclusion of an argument for merely psychological reasons and without believing the premises.Before making this point, let me provide some terminological remarks on argumentation and persuasion. I understand argumentation as an interaction between a speaker, to whom I refer as A, and a hearer, to whom I refer as B. One central purpose of argumentative interaction is to convince or persuade someone, i.e. to make someone believe a certain target proposition.with a skeptic. Suppose a speaker A intends to persuade a skeptical character S via argumentation who fulfills the following two conditions:S does not trust A concerning any premise, i.e. S does not believe any premise merely because of A uttering it.S is generally agnostic in that she does not believe any proposition (in a certain discursive domain) unless A presents an argument for it.Both attitudes are not obviously epistemic vices, rather they have, at least at first sight, some rationale. Note that S is not generally stubborn in that she does not believe any proposition regardless of whether someone presents any argument for it. Rather, she does not believe any proposition unless one presents a persuasive argument. S\u2019s attitude could be described as the general willingness to believe a proposition but only if one presents a persuasive argument for it. In this respect, S is only very cautious in forming her beliefs. Suppose now that A intends to persuade S via argumentation that p. S will only believe that p if A can persuasively argue for p. A can present an argument R for p consisting of premise p1.p based on p1 only if S also believes that p1. Due to S\u2019s skeptical character, S will believe p1 only if A presents an argument for p1 consisting of premise p2. And so on.These facts about the structure of argumentation can now be connected to Agrippa\u2019s trilemma if reinterpreted, not as an argument for skepticism, but as one about argumentation p by uttering premise pn but without presenting an argument for pn, then S will not believe pn because of A\u2019s utterance. Accordingly, S will not believe the conclusion pn\u22121 for which pn is the premise and will eventually fail to believe that p. Hence, stopping at some point without providing further argumentation will not persuade the skeptic that p.We can see how argumentation with the skeptic leads to Agrippa\u2019s trilemma. In what follows, I accept the premise that there are exactly three ways of arguing: Stopping the argumentation at some point, circular argumentation, and infinite argumentation. Let me investigate these three options with regard to argumentation with the skeptic. Take stopping at some point first. If A stops at some point arguing for p via p1, for p1 via p2, and for p2 via p. If B does not believe p when A presents an argument based on p1 for it, then B still will not believe p when A uses it as a premise for arguing for p2, at least not if B is minimally coherent. Hence, A will not persuade B via circular argumentation, and accordingly A cannot persuade our skeptical character S via circular argumentation.Let us next consider circular argumentation. Suppose that A uses circular argumentation, e.g. A argues for p.27Only infinite argumentation remains. Usually, infinitism about argumentation is rejected by claiming that human beings have finite capacities and cannot provide infinite chains of argumentation.p. Stopping at some point, presenting a circular argument, and arguing ad infinitum. First, we cannot persuade a generally skeptical person S by stopping at a certain premise because S does not believe that premise. Second, we cannot persuade S via circular argumentation because circular argumentation is never persuasive . Third, we cannot persuade S via infinite argumentation because there is no common starting point. (The impossibility of infinite argumentation is not the problem.) Since there is no further option, we cannot persuade a generally skeptical person. This is the reinterpretation of Agrippa\u2019s Trilemma as an argument about the limits of persuasive argumentation with a skeptic.We can summarize the results as follows. There are exactly three options of arguing for p requires that two parties have the same doxastic attitudes towards p. Hence, agreement is only reached via persuasive argumentation if the hearer also believes the proposition for which she argues. If a speaker persuades a hearer about a proposition that the speaker does not believe, then no agreement is reached. Accordingly, I focus hereinafter on speakers who are honest in that they only present arguments whose premises and conclusions they believe. Speakers are not necessarily honest. A speaker might have the intention to mislead a hearer or to make her believe a proposition on the basis of fallacious argumentation. However, I assume that most speakers are in most contexts honest and that dishonest speakers who present arguments based on premises that they do not believe or who argue for conclusions that they do not believe are an exception. Moreover, I will focus on unprejudiced hearers who fulfill condition PCB, i.e. who believe the conclusion of an argument because of the argument only if they believe (sufficiently many) premises. Again, hearers do not necessarily fulfill this condition.Let me now come to deep disagreement. I am interested in cases of deep disagreement that result from different beliefs that a speaker and a hearer have concerning phenomena such as the truth of premises, rationality of arguments, and reliability of sources. In this section, I will focus on beliefs about the truth of premises.p to B based on premise p1. Given that B is unprejudiced, she will not believe that p based on R unless B believes that p1. Here, two positive options are available. B already believes that p1 prior to being confronted with it, or B trusts A and believes that p1 because of A\u2019s utterance of p1. If neither of these cases obtains, then A might eventually persuade B via argumentation that p if A can present a persuasive argument R\u2019 for p1, based on premise p2 and so on. However, if A fails to reach a point where B already believes the premises that A uses or where B trusts A concerning the premises, then A will fail to persuade B, given B\u2019s unprejudicedness. Hence, we can say:p only if A presents a chain of argumentation such that, at some point B already believes the premises or B trusts A concerning some premises.Given that B is unprejudiced, A can persuade B via argumentation that Let us now also take the attitudes of speakers into account. Suppose that A is honest and only presents arguments whose premises A believes:p only if A and B agree about some premises prior to engaging in argumentation or if B trusts A concerning some premises that A presents.Given that A is honest and that B is unprejudiced, A can persuade B via argumentation that If A and B do not agree about some premises prior to engaging in argumentation or B does not trust A concerning some premises that A presents, then A cannot persuade B via argumentation. In this case, they deeply disagree and they cannot overcome this deep disagreement via argumentation.29Suppose A presents an argument R for p, stopping at some point, circular argumentation and infinite argumentation. A will not persuade B by stopping her argumentation at some point. Moreover, A cannot persuade B via circular argumentation. Finally, A is not capable of arguing ad infinitum, but even if A were capable, A would not persuade B via infinite argumentation. Hence, A cannot persuade B via argumentation. In this way, we can reconstruct Agrippa\u2019s trilemma as an argument about the limits of persuasive argumentation given that an honest speaker and an unprejudiced hearer do not share any beliefs about premises prior to engaging in argumentation and given that the hearer does not trust the speaker about any premise used.These issues on deep disagreement are linked to Agrippa\u2019s trilemma in the following way: Suppose that A is honest and that B is unprejudiced. Suppose further that A and B do not share any premises and that B does not trust A concerning any premises. A has exactly three options for arguing for JJ-principlep only if S is justified in believing that she is justified in believing that p.S is justified in believing that KK-principlep only if S knows that she knows that p.30S knows that Since JJ and KK are general principles, they also hold for beliefs in higher-level propositions. They imply that one is justified in believing that p only if one is justified in believing infinitely many meta-propositions or one knows that p only if one knows infinitely many meta-propositions.p. These are skeptical meta-regress arguments. A meta-regress argument, which is based on the JJ-principle, can be spelled out in detail as follows:The meta-regress argumentJJ-principlep only if S is justified in believing infinitely many different meta-propositions.Therefore, S is justified in believing that S cannot be justified in believing infinitely many different meta-propositions.p.Therefore, S cannot be justified in believing that p only if S is justified in believing that p.S knows that p.Therefore, S cannot know that An analogous skeptical argument can be formulated on the basis of the KK-principle. Concerning such meta-regress arguments, two questions arise: (1) Is the underlying iteration principle true? (2) Why shouldn\u2019t we be capable of justifiedly believing or knowing infinitely many meta-propositions (at least implicitly)? In contemporary epistemology, these meta-regress arguments are usually regarded as unsound and rejected by rejecting the underlying iteration principles. Hence, the first question is usually answered in the negative. The second question might be answered by tacitly assuming that being justified or knowing implies having performed an act of justifying or reasoning. Accordingly, we are only justified in believing that p if we have justified p and if we have justified that we have justified p and so on. Since we cannot perform infinitely many acts of justifying or reasoning, we cannot justifiedly believe infinitely many meta-propositions. Without going into details, one can note that this assumption is controversial. If justification or knowledge is simply a positive epistemic status of a belief, then why should this status require having performed a certain act of justification or reasoning?We next come to a skeptical regress argument involving higher-order propositions. As a starting point, an iteration principle, which has some prima facie plausibility, such as the JJ-Principle or the KK-principle, is accepted as a premise of the skeptical argument:p to B. One potential reason for why B might fail to believe that p because of R is that she does not regard R as a good or rational argument for p.p or by suspending judgment about whether it is one. In response, A can present a meta-argument for the claim that R is a rational argument for p and so on. Suppose A presents an inductive argument that an+1 is F based on the premises that a1\u2026an are F. B can, for example, challenge this argument by stressing that cases a1\u2026an being F are not sufficiently many cases for supporting that an+1 is F, or more fundamentally by rejecting inductive arguments in general. Analogously, if S presents an abductive argument for p, then B can challenge that the argument is in fact an inference to the best explanation or S can reject abductive arguments in general. In both cases, A is forced to present a meta-argument for the rationality of the first-order argument in order to persuade B. We can see how, under certain circumstances, speakers in argumentation can be forced to enter meta-regresses of justification, namely when the speaker doubts or rejects the rationality of an argument presented.In which situations should we be in need to reason that a belief, proposition, or claim is justified in order to reach a certain epistemic goal? Again, we can find an answer when considering argumentation between two parties. Suppose that A presents argument R for S does not believe the conclusion of an argument because of the argument unless S believes that the argument is rational.S suspends judgment about the rationality of an argument unless one presents a persuasive argument that the argument is rational.The first feature is a reflective one, which ensures that a skeptic about rationality is persuaded by an argument only if she also believes that the argument is rational. The second guarantees agnosticism concerning the rationality of arguments. If the skeptic suspends judgment about its rationality or rejects it as a rational argument, she does not believe the conclusion because of the argument. A skeptic about rationality of arguments is not obviously irrational in that she rejects any argument as irrational. The first feature is reasonable and the second feature characterizes someone who is generally cautious about rationality of arguments and does not believe of any argument that it is rational unless one provides reasons for it.Let us consider again an argumentation with a skeptic. Let us now take a different skeptical character into account, someone who is skeptical about the rationality of arguments and not about the truth of its premises. Such a skeptic is a character with the following two features:p. Since S does not believe that R is a rational argument for p until A presents a persuasive argument, A has to present a meta-argument R\u2019 for the claim that R is rational and so on. Since there is no argument or meta-argument of which S believes that it is rational without having been provided persuasive argumentation, S will not believe of any argument that it is rational and, consequently, will not believe via argumentation that p. Hence, nobody can convince a skeptic via argumentation about any proposition who is generally agnostic about the rationality of arguments.We can now easily see how a speaker A is forced to enter a potentially infinite meta-regress of argumentation when aiming at persuading a skeptic S about rationality. Suppose A presents argument R for Again, the reason for the impossibility of persuasion is not that speaker A would have to undergo an infinite meta-regress of argumentation for persuasion which she is not capable of doing. Rather, agreement about the rationality of an argument as a common starting point is missing. Under these conditions, A would also not persuade S via argumentation even if she were capable of undergoing such an infinite meta-regress. This is the reinterpretation of skeptical meta-regress arguments as arguments about the limits of persuading a skeptic about rationality of arguments.subjectively rational. They are subjectively rational since they follow their own beliefs about rational arguments, which do not necessarily match with the facts.33A skeptical character about the rationality of arguments is in disagreement with anybody who holds positive beliefs about the rationality of arguments. Let us now come to the more general case of deep disagreement between two parties about the rationality of arguments. In this paper, I am interested in speakers and hearers who follow at least their own standards of rational argumentation. For other subjects, there is hardly any systematic view available. Let us consider hearers who believe the conclusion of an argument because of the argument only if they believe that the argument presented is rational. Call such hearers p to B who is subjectively rational. If B does not believe that R is rational, she will not believe that p because of R. A has still the option to persuade B via a meta-argument MR that R is rational and thereby eventually persuade B that p, and so on. However, if there is no meta-argument which B believes to be rational, then A will eventually fail to persuade B that p via argumentation. Hence, it holds:p because of R because B does not believe that R is a rational argument and there is no meta-argument MR* in any chain of meta-arguments for R such that B believes that MR* is a rational argument prior to being confronted with it by A, then A cannot persuade B that p via argumentation.34If B is subjectively rational and fails to believe that Let me next come to deep disagreement. In order to investigate deep disagreement, we must also consider attitudes of speakers. Reflective speakers hold views about rational arguments. I call speakers who argue in line with their views in that they only present arguments that they believe to be rational subjectively rational. We can now state the following about single arguments:p via R.If A and B are subjectively rational and disagree about the rationality of R, then A will not persuade B that I assume that speakers and hearers are usually, though not always, subjectively rational.p via R.Suppose now that A presents argument R for p via argumentation.If A and B are both subjectively rational and do not agree about the rationality of a single meta-argument MR* in any potential chain of meta-arguments for R prior to engaging in argumentation, then A cannot persuade B that I assume that speakers and hearers are usually subjectively rational. Consequently, if A and B generally disagree about the rationality of arguments, then usually A cannot persuade B that p via argumentation. This is an instance of deep disagreement, which is irresolvable via argumentation.So far, we have focused on disagreement about the rationality of single arguments. If a speaker and a hearer disagree about the rationality of an argument, then they can potentially settle the dispute by presenting a persuasive argument about the rationality of the first argument and so on. Accordingly, a regress of meta-arguments that is potentially infinite is possible. By considering not only single arguments but also meta-arguments and potential meta-regresses we can say:To sum up this section: We cannot persuade a skeptic via argumentation who is generally agnostic about the rationality of arguments. Moreover, usually, A can only persuade B via argumentation if A and B agree about the rationality of some arguments prior to engaging in argumentation. If A and B lack this kind of agreement, then they deeply disagree.MooreanismExternal world knowledge is epistemically prior to knowledge that the skeptical hypotheses are false.We can know partly through competent inference from external world knowledge that the skeptical hypotheses are false.37In order to make her point, the skeptic must explain why Moorean reasoning cannot yield knowledge. There are various explanations of the defectiveness of Moorean reasoning on the market, defended by skeptics but also by many anti-skeptics. The most influential explanations for the defectiveness of Moorean reasoning are:Anti-Moorean argumentsBecause it cannot offer a persuasive argument to the skeptic;Because it can only deliver the result that the skeptical hypothesis is false;Because we must have additional and independent knowledge that the skeptical hypothesis is false.38Moorean reasoning is defective:In this paper, I will focus on the first anti-skeptical argument. This strategy is discussed by Pryor .Pp2\u2026pn.Repeat for  O is a reliable source.41C:Bootstrapping is, like Moorean reasoning, intuitively an epistemically defective procedure, and one way of explaining its defectiveness is by means of its persuasive defectiveness. Intuitively, bootstrapping is a flawed method of persuading someone that a source is reliable. For example, if B doubts that a gas gauge is reliably working, then A will hardly convince B about its reliability by pointing towards its indications and by performing bootstrapping reasoning.Moorean reasoning can be understood as an instance of the more general phenomenon of bootstrapping. Bootstrapping, as introduced and discussed by Vogel , 2008 isThere is wide agreement among contemporary epistemologists that justification and knowledge do not suffer from any of the two regress problems discussed above and that, therefore, these arguments are unsound. As for Mooreanism and bootstrapping, the situation is different. In fact, there is an ongoing discussion about whether S can justifiedly believe or know via Moorean reasoning or bootstrapping.O indicates that p (and perhaps thereby uttering that p), uttering that O indicates p, and then uttering the further inferences required for bootstrapping.DRO is reliable or suspends judgment about O\u2019s reliability and believes that information i is delivered by O, then B suspends judgment about the truth of i.44If B rejects that source I assume here that S does not have any further evidence about the truth of i. It is important to note that DR expresses a rational behavior. Given that S rejects that O is reliable or suspends judgment about its reliability, it is rational for S to suspend judgment about whether information delivered by O is true. For example, it is irrational for a subject to believe that a certain thermometer is unreliable but still believe what the thermometer indicates on the basis of its indication. Rather it is rational to suspend judgment about the truth of the indication. The rationality involved here is a kind of internal coherence of the subject\u2019s body of beliefs, which must not be confused with doxastic or propositional justification. Given that S doubts that O is reliable, it is rational for S to suspend judgment about the truth of information delivered by O. This doubt however, might be justified or not.45Let us see in more detail why bootstrapping and Moorean reasoning are not instances of persuasive argumentation. Bootstrapping argumentation roughly involves a speaker A demonstrating that source Argument for the unpersuasiveness of bootstrappingO is reliable or suspends judgment about O\u2019s reliability.Suppose that B rejects that source c because of A\u2019s argumentation consisting of premises p1\u2026pn and conclusion c only if B believes sufficiently many premises p1\u2026pn. (PCB)B believes that O is reliable (or suspends judgment about O\u2019s reliability) and believes that information i is delivered by O, then B suspends judgment about the truth of i. (DR)If B rejects that O constitutes the premises of an argument that O is reliable. (Definition of bootstrapping argumentation)In case of bootstrapping understood as argumentation, information delivered by usually recognizes A\u2019s bootstrapping argumentation about O as bootstrapping argumentation.46B O is reliable via bootstrapping.Therefore, A usually does not persuade B that Take Vogel\u2019s example of the gas gauge G. Suppose that B suspends judgment about the reliability of G. If A wants to persuade B via bootstrapping argumentation that G is reliable, then this project will fail. B does not believe the indications of G, since she suspends judgment about the reliability of G, and, consequently, S does not believe the conclusion of the bootstrapping argument.Putting the pieces together, we can now formulate an argument for why bootstrapping is not a persuasive way of arguing.Moorean argumentationp by pointing towards S\u2019s experienceA demonstrates that S\u2019s experience delivers that pB thereby believes that S\u2019s sense apparatus delivers that pA utters that p is true based on S\u2019s experience as of p (DR)B suspends judgment about whether p (PCB)Therefore, B does not believe that S\u2019s experience accurately indicates that \u2026Therefore, B does not believe via Moorean argumentation that S\u2019s sense apparatus is reliableSuppose S\u2019s inner skeptic B doubts that S\u2019s sense apparatus is reliable and A, S\u2019s inner believer, aims to persuade B about its reliability via Moorean argumentation.This is the reinterpretation of the argument for external world skepticism including the claim that Moorean reasoning is epistemically flawed for it is not persuasive as an argument about the limits of argumentation.Let us now investigate the particular case of Moorean reasoning. With Moorean reasoning, the process of argumentation is not one between two actual persons. Rather, it must be understood as an argumentation between an inner believer and an inner skeptic.O is reliable then A can use another source O\u2019 for persuading B that O is reliable. For example, A can use a dipstick for demonstrating that a gas gauge is reliable. However, A will succeed in persuading B that O is reliable via O\u2019 only if B believes that O\u2019 is reliable, and so on. This way, problems concerning Moorean reasoning can collapse into an infinite regress problem.50Let us now consider the case of arguing with a skeptic S, not necessarily an inner one, who is generally agnostic about the reliability of sources and suspends judgment about the reliability of any source unless one provides a persuasive demonstration for its reliability.p, then A cannot persuade B via a source that p.If B doubts the reliability of any source that A can use for delivering premises for an argument for Suppose now that A is honest about sources in that she uses sources for argumentation only if A believes that these sources are reliable and B follows DR. In this case, it holds:p if A and B agree about the reliability of a source prior to engaging in argumentation.A can only persuade B via a source that If A and B lack any agreement about the reliability of sources that A can use in order to argue for p, then A fails to persuade B that p for a systematic reason. In this case, speaker and hearer deeply disagree and this disagreement cannot be resolved by consulting any source.51This analysis of the limits of argumentation with skeptics about reliability is of rather theoretical interest. Let us now investigate the consequences for deep disagreement, which is a broader and more relevant social phenomenon. By generalizing the argument for the impossibility of persuading a skeptic who is skeptical about the reliability of sources and assuming that B follows DR we can say:Some skeptical arguments have a certain intuitive appeal, but they are not sound arguments about the extent of knowledge. However, they can be reinterpreted as arguments about the preconditions and limits of persuasive argumentation, explaining why we cannot persuade skeptical characters. Moreover, these reinterpretations reveal certain instances of deep disagreement. (1) A reinterpretation of Agrippa\u2019s trilemma shows that we cannot persuade a skeptic who is agnostic about any proposition by stopping at a certain point, circular argumentation, or infinite argumentation. Two parties deeply and irresolvably disagree if they do not share any agreement about sufficiently many premises prior to engaging in argumentation. (2) Skeptical meta-regress arguments can be reinterpreted as showing that we cannot persuade a skeptic who is generally agnostic about the rationality of arguments. There is deep and irresolvable disagreement between two parties who do not share any agreement about the rationality of arguments prior to engaging in argumentation. (3) Bootstrapping and Moorean reasoning are not instances of persuasive argumentation. Two parties deeply and irresolvably disagree if they do not agree about the reliability of any source prior to engaging in argumentation.52p shows that one does not know that p. However, this line of thought is mistaken. The insights about the corresponding versions of deep disagreement show that the capacity of persuading someone via argumentation is determined by whether speaker and hearer share sufficiently many beliefs about the truth of premises, rationality of arguments, or reliability of sources. It does not depend on the epistemic position of the speaker. A speaker might be in a perfect epistemic position concerning a proposition, i.e. she might know the proposition according to the highest standards for knowledge, yet she might fail to persuade a skeptic or someone who does not share the beliefs required for persuasive argumentation. Therefore, knowing that p or being justified to believe that p does not imply having the capacity to persuasively argue for p. The skeptical move of pointing towards the persuasive defectiveness of certain arguments and then concluding that one cannot know or be justified to believe is illegitimate.53One might object that skepticism enters through the backdoor when reinterpreting skeptical arguments as arguments about the limits of argumentation with the skeptic since the fact that one cannot provide a persuasive argument to the skeptic for As for deep disagreement, two questions are of particular interest: What is deep disagreement? Is deep disagreement resolvable or not? Both questions have been settled. We see that there are at least three kinds of deep disagreement, one relying on systematic disagreement about premises, one about the rationality of arguments, and one about the reliability of sources.The theses about the limits of persuasive argumentation with a skeptic are of rather theoretical interest, providing a new view on well-known skeptical arguments. However, the theses about variants of deep disagreement and the explanation for their irresolvability are of significant social relevance. Actual instances for any type of deep disagreement can presumably be found, for example, concerning the preconditions of intercultural argumentation. However, finding and discussing such applications is beyond the scope of this paper."}
{"text": "We have now added O.D. as a corresponding author due to her role in providing resources and supervision for the study and her specialized contribution to the philosophical implications of our results. The change does not affect any of the other sections in the article or its conclusions. The authors apologize for any confusion caused to the readers."}
{"text": "Nearly a century has passed since the first studies of life in the subsurface . Ricardo Amils: Conceptualization .The authors declare that they do not have any conflict of interest."}
{"text": "The authors wish to correct the following error in the original paper .An additional affiliation  has been added to the first author Lulu Liu. Due to this change, the numbers of the rest of the affiliations of each author were updated.The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "This Expression of Concern is for the above article, published online on 14 April 2022 in Wiley Online Library (wileyonlinelibrary.com), and has been published by agreement between the journal Editor\u2010in\u2010Chief and John Wiley & Sons, Ltd. The Expression of Concern has been agreed due to concerns regarding data presented in Table 2. A third party has brought to our attention that they cannot repeat this work and that some mesh terms are not accurate. As such they question the accuracy of the data in Tables 1 and 2 as they find some inconsistencies in the numbers of eligible articles based on their re\u2010analysis of the approach. The IWJ editorial team have been unable to reach the authors of this article for comment. The author's institution has also been contacted without success. Since we cannot verify the accuracy of the challenge or the original data, the journal is issuing this Expression of Concern to alert readers.Ji, X, Zhao, Y, Zhang, L, Liu, Y. Benign prostatic hyperplasia wound after surgical removal in subjects on anticoagulant or antiplatelet therapy: A meta\u2010analysis. Int Wound J. 2022; 19(8): 1990\u20131999. doi:"}
{"text": "Retraction Note to: Stem Cell Research & Therapy (2018) 9:348 10.1186/s13287-018-1082-zThe Editors-in-Chief have retracted this article. After publication, concerns were raised regarding the binding site between IL-6 mRNA and miR-665. Specifically, the sequence of IL6 3'UTR reported in this article appears to refer to ILR6 rather than IL6. Additionally, in the TargetScan database, miR-665 does not appear to be among the predicted miRNAs targeting IL6. Further checks by the Publisher identified the following concerns with the presented data:In Figs. 4f and 6g, three images appear to originate from the same sample .In Figs. 5f, 6f and 7a, all western blot images have highly similar background features, and a number of bands appear to have straight vertical edges, which are inconsistent with the backgrounds.The authors have stated that Figs. 4f and 6g indeed contain errors, and that the western blots are not presented in their original state. They have provided raw data to address these concerns; however, these data contain further inconsistencies and highly similar images. The Editors-in-Chief therefore no longer have confidence in the data and conclusions of this article.Ruoyu Wu has not explicitly stated whether they agree to this retraction notice. Jihao Ruan, Yongjin Sun, Mengyu Liu, Zhuang Sha, Cunyi Fan and Qingkai Wu have not responded to any correspondence from the editor or publisher about this retraction."}
{"text": "In conversational query answering systems, context plays a significant role in accurately and meaningfully carrying it forward. In many chatbots, such as in Expedia, the discussion quickly degenerates into circling back to restarting the conversation or to inviting a live agent to intervene because the bot could not grasp the context. Contexts shorten interactions by way of implied query constraints to narrow search and to not repeat them in subsequent queries. In this paper, we introduce a novel way of viewing contexts as a distance function via the concept of query relaxation. We demonstrate that a typed domain distance function is sufficient to model context in a conversation. Our approach is based on the idea of non-monotonic constraint inheritance in a context hierarchy. Early research in database (DB) and artificial intelligence (AI) context has been modeled sometimes indirectly without an explicit treatment. For example, cooperative query answering , 2, indeRestaurants below.For example, consider the query against the table Q1: Is there a five star rated Vietnamese restaurant in Moscow, Idaho?Q1. In CoBase |end|backtrack|fresh conversation;A conversation begins with begin conversation instruction either in cumulative or in disjunctive mode. It can end with end conversation instruction. An entirely new conversation can be started from inside an active conversation with fresh conversation instruction. Conversations are unnamed sessions and are not persistent. Therefore, once a conversation is abandoned (using an end conversation instruction), it cannot be re-entered; it must start afresh. However, a new and additional initial context can be established by issuing fresh conversation instruction without ending a conversation, giving rise to conversation forests.Once inside a conversation, a contextual query can begin. While a query generally has a traditional SQL syntax, it is annotated with a context modifier of the following form with a well-defined grammar.C1 [parent C2] as\u2003context A1, A2 \u2026, An\u2003select r1, r2 \u2026 , kr\u2003from \u03b8;\u2003where C1 and C2 are conversation wide distinct identifiers2. The construction and issuance of these contextual queries must follow specific protocols and deserve a substantial discussion. However, in this article we want to be brief and only discuss essential components of ConSQL.In the above form, C statement without the parent option since it must be the root, and the only context C statement until fresh conversation is issued. All subsequent statements must be of the form context C parent C\u2032 to place the query under a node in the conversation or context tree. In both instances, a stack pointer points to the current context and all computations take place within its environment. To relocate the context pointer to alter the computational environment, backtrack conversation command can be issued to move the context toward the parent of the node. In the current edition of ConSQL, we do not see any need for a forward context pointer relocation particularly when there are multiple candidates, e.g., box 1 in In a new or fresh conversation, the first contextual query must start with context While several syntactic shortcuts are possible, we do not overburden the syntax of ConSQL to make querying easier since such shortcuts can be supported in the user interfaces in some fashion. For example, currently we require that the the query in step 3 be phrased in ConSQL as follows.Q4: context C parent D as\u2003#, Fare\u2003select FlightFlights\u2003from Origin=\u201cBWI\u201d and Destination=\u201cSSA\u201d and Fare<500 and Date=11/10;\u2003where where the initial context is set up asQ3: context D as\u2003#, Fare\u2003select FlightFlights\u2003from Origin=\u201cGEG\u201d and Destination=\u201cSSA\u201d and Fare<500 and Date=11/10;\u2003where Q5: context C parent D as\u2003#, Fare\u2003select FlightFlights\u2003from Origin=\u201cBWI\u201d;;\u2003where it would essentially mean the same query Q4 since it inherits all the unaltered constraints of Q3. In principle, we also allow adding new relations in the from clause in a subordinate context, i.e., monotonic inflation of information space so that all previously listed constraints can be enforced. For this reason also, we require the full syntax (not the Q5 form) not to make it difficult when mapping to SQL for execution and be counter intuitive.Again, note that it is possible to imagine several fancy syntactic alternatives. Basically what we want in a modified context is to alter a condition in the parent context to relax it. Therefore, even if we allowed the syntax4.2The semantics of ConSQL queries can be established based on the SQL queries with some fine tuning. In the current edition of ConSQL, we choose a tuple similarity based semantics for ConSQL in the following way.Definition 1 (Relaxation). Given two conditionsover an attribute A in query Q, is called a relaxation or a relaxed condition, ifwhere e is the evaluation function of querywith conditionand i \u2208 {1, 2}.4.2.1We assume that there is a type-polymorphic distance function Definition 2 (Close to Intent). Letbe a relaxation ofover an attribute A of type t, and let c2and c1be the constants respectively. The closeness of a value v to the initial context or the intent is then given byv1 and v2, v1 is closer to the intent than v2 if Thus, given two values Definition 3 (Preferred Tuples). Let t is a tuple over the schemeAlso letare relaxations corresponding to the initial contextswhereThe (multiplicative) tuple closenessis given byFinally, for two tuplesandis preferred overifholds.k response upper limit, we now can easily choose the top k closest responses.The tuple closeness ranges between 0 and 1. It must be noted here that preference relation is defined only using the relaxation conditions over the attributes involved, i.e., the remaining attributes do not play any role. Given a top-4.3Implementation of ConSQL is ongoing and a full discussion of its implementation is outside the scope of this paper. Issues such as how to map queries to SQL for execution, how to choose preferred tuples as response, how to implement cumulative and disjunctive context switching, are deferred to a later article. In this section we mainly focus on a generic distance function to compute the closeness of a value to help implement the idea of preferred tuples instead.In general, all relaxations imply acceptable deviations. In CoBase, the relaxation was based on a carefully constructed TAH. Such a structure makes it easier to compute deviations for almost all types of objects or values. For example, we can potentially create a TAH for airports based on GPS locations, overall operation, average delay, or traffic volume, and so many other ways or dimensions. However, as mentioned earlier, developing and maintaining a multi-dimensional TAH is truly complicated, if not impossible.\u03b4t that is capable of returning the distance between two objects x and y of type t that will range between 0 and 1, relative to y within a linear distance between y and z. This function will measure how close x is to y given that the object z is assumed to be farther than y satisfying triangular inequality relationship in a metric space, i.e., d \u2264 d + d.A practical strategy could be to develop a polymorphic distance function 5Context is a complex concept to model and serves a unique purpose in various applications. Therefore its definition and application varies. In this article, we have defined context as the intent of a query the response to which we try to approximate as closely as possible. We have leveraged the idea of query relaxation that previously played a major role in designing cooperative query answering systems, and have shown that in chatbot type applications our concept of context can play a significant role in improving conversations and services. The idea presented is at an early stage. The implementation of a query processor is ongoing while its efficacy has been tested as a prototype implementation see  by proce"}
{"text": "Haroun, Khabab Abbasher Hussien Mohamed Ahmed, Osman Amir, Mohammed Alfatih, Akram Khalid Al Tigany Al Shiekh, Mazin Abdelraham Osman Ahmed, Alshareef Nour, Radi Tofaha Alhusseini, Waddah Aljaely Mohammed Osman, Mohamed Abdulkarim, Mohammed Eltahier Abdalla Omer, Ibrahim M. Mahgoub, HSR2523, https://onlinelibrary.wiley.com/doi/full/10.1002/hsr2.523} has been retracted by agreement between the journal's Editor\u2010in\u2010Chief, Charles Young and John Wiley & Sons Ltd. The retraction has been agreed given the journal has received evidence confirming that the peer review process of this paper was manipulated. As a result, the conclusions reported in the article are not considered reliable.The above article, published online on {First published: 28 February 2022} in Wiley Online Library { Haroun, Khabab Abbasher Hussien Mohamed Ahmed, Osman Amir, Mohammed Alfatih, Akram Khalid Al Tigany Al Shiekh, Mazin Abdelraham Osman Ahmed, Alshareef Nour, Radi Tofaha Alhusseini, Waddah Aljaely Mohammed Osman, Mohamed Abdulkarim, Mohammed Eltahier Abdalla Omer, Ibrahim M. Mahgoub, HSR2523, https://onlinelibrary.wiley.com/doi/full/10.1002/hsr2.523} has been retracted by agreement between the journal's Editor\u2010in\u2010Chief, Charles Young and John Wiley & Sons Ltd. The retraction has been agreed given the journal has received evidence confirming that the peer review process of this paper was manipulated. As a result, the conclusions reported in the article are not considered reliable.The above article, published online on {First published: 28 February 2022} in Wiley Online Library {"}
{"text": "Retraction Note: BMC Cancer 19, 400 (2019)https://doi.org/10.1186/s12885-019-5593-5In Fig.\u00a02b, the circRNA overexpression group images appear highly similar to the Control group in Fig.\u00a02d of\u00a0(, now retFigs. 4c, 4d and 8f appear to contain overlapping panels with Figs. 4d, 4e, 7e and 7f of\u00a0;In Fig.\u00a05a, Mock SCC25 and CAL27 appear to contain an overlapping area.In Fig.\u00a05b, Mock SCC25 and CAL27 appear to original from the same sample, with rotation and minor modification.The Editor has retracted this article at the Corresponding Author's request. After publication, concerns were raised regarding highly similar images used in this and other articles, specifically:The authors have stated that these images were misused. The Editor therefore no longer has confidence in the presented data.Wen Su, Feng Wang, Yuehong Shen and Hongyu Yang agree to this retraction. Yufan Wang, Shuai Sun and Minghua Li have not responded to any correspondence from the editor or publisher about this retraction."}
{"text": "The result of the dose calculation is not affected by this. The authors regret the confusion this may have caused.In the article by Gr\u00fcnewald  al. 2023, there w"}
{"text": "Both the Editor and the authors apologize to the readership for any inconvenience caused.Following the publication of this paper, it was drawn to the Editor's attention by a concerned reader that, in Fig. 4 on p. 650, the same \u03b2-actin bands had apparently been used to show the experimental effects of the proteasome inhibitor MG-132 on c-FLIP in HSC-2 cells in Fig. 4A, and the effects of MG-132 on IAPs in HSC-3 cells in Fig. 4B. In addition, for the fourth lane in the gel showing the effects of MG-132 on c-FLIP in HSC-3 cells, this should have been labelled as \u2018+MG-132 / +TRAIL\u2019 (not as \u2018-/-\u2019). Upon contacting the authors in relation to this matter, they could only admit that errors had been made in the preparation of the figure; moreover, they no longer had access to the original data owing to the time that has elapsed since the publication of the paper, and it would be impossible for them to now repeat this experiment. After having considered this matter and in conjunction with a request made by the authors, the Editor of"}
{"text": "Retraction Note: J Exp Clin Cancer Res 38, 57 (2019)https://doi.org/10.1186/s13046-019-1070-xThe Editor-in-Chief has retracted this article. Concerns were raised regarding Figure 4B: the LN229 and U251 ZEB2 bands appear to be identical but flipped horizontally. Additionally, the authors have been unable to provide convincing documentation that ethics approval was obtained for this study. The Editor-in-Chief therefore no longer have confidence in the results and conclusions of this article.Author Shuang Feng disagrees with this retraction. The other authors have not responded to correspondence regarding this retraction."}
{"text": "Correction: Diabetol Metab Syndr (2019) 11:85 10.1186/s13098-019-0482-2Following publication of the original article , the authttps://www.pfizer.com). Support for publication fees and open access is provided by ECLAT srl, a research based spin-off company of the University of Catania, with the help of a grant from the Foundation for a Smoke-Free World Inc., a US nonprofit 501(c)(3) private foundation (https://www.smokefreeworld.org)\u00a0which receives funding from Philip Morris.\u00a0The contents, selection, and presentation of facts, as well as any opinions expressed herein are the sole responsibility of the authors and under no circumstances shall be regarded as reflecting the positions of the sponsors.This paper was partly supported by grant WS5086648 from GRAND , an independently reviewed competitive grants program funded by Pfizer Inc,\u00a0a US biopharmaceutical company\u00a0active in the research, production and marketing of smoking cessation drugs ("}
{"text": "Zheng ZZ performed the experiments. Yang JB, Wei XP, Song TN, Meng YQ participated in the completion of the operations. Zheng ZZ, Chen YZ, Liu Q analyzed the data. All the authors had access to the data. All authors read and approved the final manuscript as submitted."}
{"text": "Editorial Expression of Concern: HORM CANC (2013) 4:176\u2013185 10.1007/s12672-013-0137-yThe Editor-in-Chief would like to alert readers that concerns have been raised regarding Fig.\u00a02 presented in this article. Similarities have been noted in lanes 2 and 6 of Fig.\u00a02B. Readers are advised to interpret the results with caution. Authors have not responded to any correspondence from the publisher about this editorial expression of concern."}
{"text": "Retraction Note: Cardiovascular Toxicology (2022) 22:916\u2013928https://doi.org/10.1007/s12012-022-09768-0I\ufefft appears a GADPH has been re-used in Figs. 1A, 1B and 2B.In Fig. 1, TNFa and NFkB look very similar to each other.In Fig. 2B, the first and last lanes of the GPx blot look very similar to each other.The Editor in Chief has retracted this article because of the following issues:The authors provided raw data which did not contradict these concerns and stated they did use the same GAPDH blot in the 3 figures. The Editor in Chief, therefore, has lost confidence in the integrity of the article's findings. None of the authors agree to this retraction."}
{"text": "In \u201cPersonalized Precision Medicine for Health Care Professionals: Development of a Competency Framework\u201d , the authors noted several errors.In the originally published paper, a typographical error in the corresponding author\u2019s email address, formatted as:fmartin@isciiI.esThis has been changed to:fmartin@isciii.esIn the last paragraph of the \u201cIntroduction\u201d section, the authors noted that one reference was not included in the original manuscript. A new citation (numbered 7) has been added to the list of references and cited in the following sentence:Accordingly, this project aimed to define a proposal of common domains and competencies for today\u2019s health care professionals, as well as those who will emerge in the future .The citation added to the reference list is as follows:Fundaci\u00f3n Instituto Roche. Competency Personalized Precision Medicine for healthcare professionals. 2021. URL: https://www.institutoroche.es/static/pdfs/ Final_Report_Competencies_PPM_DEF1.pdf [accessed 2023-02-08]The addition of this citation modified the order of the rest of the citations.In Table 2, an acronym was originally typed incorrectly as \u201cOLPPDGDR\u201d. This has been corrected to \u201cOLPDPGDR\u201d both in row \u201cD2.11\u201d and in the corresponding footnote \u201cc\u201d. The same error occurred in Figure 4, which has also been updated accordingly.An error was also noted in the first paragraph of the \u201cAcknowledgments\u201d section. The sentence:We are grateful to the working group for aiding the development of this project, contributing to the preparation of this document, and sharing their perspectives on the key elements and training needs for the definition of competencies in the areas of interest of personalized precision medicine.Has been changed to:We are grateful to the Fundaci\u00f3n Instituto Roche and the working group for aiding the development of this project, and sharing their perspectives on the key elements and training needs for the definition of competencies in the areas of interest of personalized precision medicine.The correction will appear in the online version of the paper on the JMIR Publications website on February 21, 2023, together with the publication of this correction notice. Because this was made after submission to full-text repositories, the corrected article has also been resubmitted to those repositories."}
{"text": "RSC Advances article due to concerns with the reliability of the data.The Royal Society of Chemistry hereby wholly retracts this Fig. 2D sh-MRPS23 panel is identical to Fig. 4C sh-MRPS23 panel (bottom left) and has some strong similarity with Fig. 4C sh-MRPS23 + LPS + PDTC panel (bottom right). A section in the panel for Fig. 2D sh-MRPS23 has strong similarity with Fig. 4C sh-Control + LPS + PDTC panel (top right). A section in the panel for Fig. 2D sh-control has strong similarity to a section in Fig. 4C sh-control + LPS + PDTC panel (top right).In Fig. 4C a section in the panel for sh-control (top left) is a stretched version of a section in the panel sh-control with LPS and PDTC (top right).Fig. 3C contains multiple duplicated images. The first four tumour images in the Control group are identical to the last four images in the sh-MRPS23 + LPS group. The third image in the control group is identical to the first image in the sh-control + LPS group. The final image in the control group is identical to the third image in the sh-MRPS23 group. The third image in the sh-MRPS23 group is identical to the first image in the sh-MRPS23 + LPS group.The authors were asked to provide the raw data for this article but did not respond. Given the significance of the concerns about the validity of the data, and the lack of raw data, the findings presented in this paper are not reliable.The authors were informed about the retraction of the article but have not responded.RSC AdvancesSigned: Laura Fisher, Executive Editor, Date: 18/7/2023"}
{"text": "This article has been retracted: Aging has completed its investigation of this paper. We found overlap between several transwell assay images used for multiple figures and data published by different authors. Specifically, in Figure 2E, the motility image for A549 si-NC overlaps an image from [age from . In Figuage from . In Figuage from ,7. Finalage from . As a reThe Administration of the Shandong University, Guangxi Medical University and their respective affiliated hospitals was notified about the retraction by Aging Journal because of the improper use of multiple pictures included in this manuscript. The authors apologize for any inconvenience this retraction has caused for the scientific community."}
{"text": "There was an error in the original publication  in the dThe original equation was:The correct equation is:f0 used in the text were obtained using the equation and the correction does not change the claims or arguments of this paper.All The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "In \u201ciCHECK-DH: Guidelines and Checklist for the Reporting on Digital Health Implementations\u201d , the authors noted one error.The degree list for author Christian Lovis was previously reported as:MD, PhDAnd has now been changed to:MPH, MDThe correction will appear in the online version of the paper on the JMIR Publications website on May 18, 2023 together with the publication of this correction notice. Because this was made after submission to PubMed, PubMed Central, and other full-text repositories, the corrected article has also been resubmitted to those repositories."}
{"text": "Corrigendum to: Evaluation of cerebrospinal fluid neurofilament light chain levels in multiple sclerosis and non-demyelinating diseases of the central nervous system: clinical and biochemical perspective .This corrigendum corrects funding information to: This project was partly supported by Gazi University Scientific Research Projects Coordination Unit (BAP) (project code: 01/2019-38). The authors would like to thank Gazi University for funding this project. The authors sincerely apologize for the error and confirm that this correction does not change the conclusion of the article."}
{"text": "Retraction note: Nanoscale Res Lett (2021) 16:310.1186/s11671-020-03452-4The Editors in Chief have retracted this article. After publication, concerns were raised about the appearance of the Western blots along with the following issues:Unlikely appearance of the data presented in the flow cytometry histograms in Fig.\u00a05A/E, in particular the unusually-looking peaks;In Table 1 \"Primer sequence\", the putative PTEN primers appear to align to NF kappa B instead.The authors provided quantification data for the Western blots but were unable to provide uncropped gels and blots. The Editors, therefore, have lost confidence in the integrity of the article's findings. The authors did not explicitly state whether they agree to this retraction."}
{"text": "In \"Assessment of the Efficacy, Safety, and Effectiveness of Weight Control and Obesity Management Mobile Health Interventions: Systematic Review\" :e12612) the authors noted one clarification that should be added.In the Acknowledgments section it says:All authors contributed equally. The research for this paper was fully funded by the Instituto de Salud Carlos III from the Spanish Ministry of Science, Innovation and Universities, grant number PI16/01764.It should say:All authors contributed equally. The research for this paper was fully funded by the Instituto de Salud Carlos III from the Spanish Ministry of Science, Innovation and Universities, grant number PI16/01764 co-funded by FEDER.The correction will appear in the online version of the paper on the JMIR Publications website on April 10, 2023 together with the publication of this correction notice. Because this was made after submission to PubMed, PubMed Central, and other full-text repositories, the corrected article has also been resubmitted to those repositories."}
{"text": "The authors regret that an incorrect grant number was shown in the acknowledgements section of the published article. The corrected section should read:This study was supported by the Technology Development Program (S2830047) by the Ministry of SMEs and Startups (MSS) and by Technology Development Project for Safety Management of Household Chemical Products (2022002980010) by the Ministry of Environment (ME), Republic of Korea.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "However, Guest Editors of this Special Issue later identified thispaper as a contribution worth mention related to the Special Issue.Therefore, the paper has been linked to the Special Issue.This paper was originally notrequested by the authors for consideration in the submissions forthe Methods for Omics Research 2023 Special Issue,"}
{"text": "In the original article, inthe third sentence of the sixth paragraph in the \u201cMATERIALSAND METHODS\u201d section, \u201c700 \u03bcL of MES buffer \u201d was written instead of \u201c700 \u03bcL ofpure water\u201d . This small mistakedue to oversight has been rectified below. The authors apologize forthe error.Rectified Sentence in the Sixth Paragraph in \u201cMATERIALSAND METHODS\u201d Section:g and 25\u00b0C for 3 min and washed with 700 \u03bcL of pure water six times.The suspension was centrifugedat 5000"}
{"text": "Clinical Neuroradiology also slightly dropped with the impact factor from 3.156 to\u00a02.8  but many other factors.Clinical Neuroradiology to establish this journal as one of the leading journals in the field.We would like to thank all authors and reviewers for their continuous support of Martin BendszusEditor-in-Chief"}
{"text": "This is a peer-review report submitted for the paper \u201cAre We Sure We Fully Understand What an Infodemic Is? A Global Perspective on Infodemiological Problems.\u201dDear Authors,This paper  presents"}
{"text": "Furthermore, they regret that these errors were introduced into the paper, even though they did not substantially alter any of the major conclusions reported in the paper, and apologize to the readership for any inconvenience caused.The corrected versions of"}
{"text": "In \u201cThe Use of Person-Centered Language in Medical Research Journals Focusing on Psoriasis: Cross-sectional Analysis\u201d :e28415) two errors were noted.In the originally published manuscript, incorrect ORCID numbers were listed for authors Benjamin Heigle and Matt Vassar. The ORCID numbers have been corrected as follows:Benjamin Heigle: 0000-0003-3724-0756Matt Vassar: 0000-0003-2859-6152The correction will appear in the online version of the paper on the JMIR Publications website on July 16, 2021, together with the publication of this correction notice. Because this was made after submission to PubMed, PubMed Central, and other full-text repositories, the corrected article has also been resubmitted to those repositories."}
{"text": "J Arrhythmia. 2023;39:227\u201330. https://doi.org/10.1002/joa3.12817Retraction: Hasegawa K, Fukuoka Y, Ohno S, Horie M, Tada H. Computerized misinterpretation of QT interval in 12\u2010lead electrocardiogram and its clinical consequences: a case of recurrent syncope. Journal of Arrhythmia, published online on January 30, 2023, in Wiley Online Library (wileyonlinelibrary.com) and in Volume 39, pp. 227\u2013230, has been retracted by agreement between the authors, the journal Editor in Chief Kazuo Matsumoto and John Wiley & Sons Ltd. The retraction has been agreed due to duplication with a previously published article from the same group of authors.The above article from  J Arrhythmia. 2023;39:227\u201330. https://doi.org/10.1002/joa3.12817Retraction: Hasegawa K, Fukuoka Y, Ohno S, Horie M, Tada H. Computerized misinterpretation of QT interval in 12\u2010lead electrocardiogram and its clinical consequences: a case of recurrent syncope. Journal of Arrhythmia, published online on January 30, 2023, in Wiley Online Library (wileyonlinelibrary.com) and in Volume 39, pp. 227\u2013230, has been retracted by agreement between the authors, the journal Editor in Chief Kazuo Matsumoto and John Wiley & Sons Ltd. The retraction has been agreed due to duplication with a previously published article from the same group of authors.The above article from"}
{"text": "The correct information should be \u201cThis project received funding from the The authors would like to apologise for any inconvenience caused."}
{"text": "Jin TY and Li ZH analyzed the data. Jin TY, Tang JW and Xu J contributed analysis tools. Chen L and He ZC provided critical inputs on design, analysis and interpretation of the study. All the authors had access to the data. All authors read and approved the final manuscript as submitted."}
{"text": "Following the publication and correction of this article , 2, conc\u25cb Fig 3A IFN-\u03b3 and Fig 5A IFN-\u03b3;\u25cb Fig 3A IL-4 and Fig 5A IL-4;\u25cb Fig 3A TGF-\u03b2 and Fig 5A TGF-\u03b2;\u25cb Fig 3A GAPDH and Fig 5A GAPDH.The following Untreated Control RT-PCR results appear similar:\u25cb The lower left and right quadrants of the Fig 5D IFN-\u03b3 \u201cUntreated unfixed TAMs\u201d and TGF-\u03b2 \u201cCuNG-treated unfixed TAMs, in transwell\u201d panels;\u25cb The Fig 6C 72h \u201cIn vitro CuNG Treated TAMs\u201d panel and 96h \u201cIn vitro CuNG Treated TAMs panel\u201d.The following FACS results appear more similar than would be expected from independent results:Although the similar untreated control samples appear to represent the same experimental conditions, the authors commented that the Fig 3A results were obtained from experiments conducted at a different time than the Fig 5A results, calling into question whether one or both of these experiments were conducted alongside the appropriate controls. The corresponding author provided gel data underlying the published Fig 3A results; these underlying data were incomplete and suggest that the Fig 3A results were prepared from spliced gels. The original data underlying Fig 5A are no longer available.Additional concerns were raised regarding data presented in Figs 3A and 5A, but due to the low resolution of the published figures and the incomplete underlying data set, the journal has not been able to assess the merit of the additional concerns raised with these figures.The authors explained that the Fig 5D experiments were conducted on the same day and on the same instrument. However, this does not clarify the level of similarity observed between these two panels. Regarding the similarity between the Fig 6C results, the authors commented that it is possible an error was made during the figure preparation. The authors provided the data underlying the Fig 6C results and a replacement Fig 6. However, the original FACS data underlying Fig 5D are no longer available. In the absence of the original FACS data underlying Fig 5D, the journal is unable to confirm the FACS results presented in this figure.PLOS ONE Editors retract this article.In light of the concerns affecting multiple figure panels that question the reliability of these data, the SG agreed with the retraction. SKC and SC did not agree with the retraction. AM, JMB, PC, AG, AA, DM, RB, MA, JB, PKD, GS, MC, and TD either did not respond directly or could not be reached."}
{"text": "BMC Public Health (2023) 23:51010.1186/s12889-023-15173-1During the publication process 2 errors were introduced in the PDF publication:1) In page 26, the text \u201cNot introduction of solid, semi-solid or soft food (6-8 months)\u201d was missing in the IYCF component column.2) In page 27, the text \u201cTariqujjaman et al. (2022) [61]\u201d was missing in the Author, year column.The original article has been updated to correct these errors. The publisher apologizes to the authors & readers for the inconvenience."}
{"text": "Nature Communications 10.1038/s41467-023-41619-6, published online 21 September 2023Correction to: The original version of this Article contained an error in the results, which incorrectly read:\u03c1 of temperature xmap farmland NPP indicate that farmland NPP is not a cause of temperature. And the much-smaller \u03c1 of precipitation xmap farmland NPP majorly result from the above-introduced enslaved effect from the strong causal influence of precipitation on farmland NPP. In other words, farmland NPP can partially reflect precipitation.\u2019\u2018The zero The correct version now reads:\u03c1 of precipitation xmap farmland NPP indicate that farmland NPP is not a cause of precipitation. And the much-smaller \u03c1 of temperature xmap farmland NPP majorly result from the above-introduced enslaved effect from the strong causal influence of temperature on farmland NPP. In other words, farmland NPP can partially reflect temperature.\u2019\u2018The zero This has been corrected in both the PDF and HTML versions of the Article."}
{"text": "Retraction Note: BMC Complement Med Ther 22, 158 (2022)https://doi.org/10.1186/s12906-022-03629-7The Editor has retracted this article. After publication, concerns were raised regarding image similarities among the panels in Fig. 8. Specifically:The p-JNK ENC image appears to overlap with p-JNK Dexa;The NF-\u03baB Normal control appears to overlap with NF-\u03baB ECN.Additionally, Fig. 8 TNF-a Dexa and ECN images appear to overlap with Fig. 13 TNF-a NCHDH and CFA in [The authors have provided the raw data to address these concerns. However, further checks by the Publisher identified numerous irregularities in the raw data, and further cases of data overlap with . The EdiSalman Khan does not agree to this retraction. None of the other authors have responded to any correspondence from the editor or publisher about this retraction."}
{"text": "This is the authors\u2019 response to peer-review reports for \u201cEmergence of the First Strains of SARS-CoV-2 Lineage B.1.1.7 in Romania: Genomic Analysis.\u201d1. The manuscript  needs soResponse: Per the reviewer\u2019s [viewer\u2019s  comment,1. In the Materials and Methods section, authors mentioned that \u201cTwenty samples, collected from patients in the cities of Cluj, Craiova and Suceava counties from Romania were selected for analysis, including patients with possible contacts with UK infected individuals.\u201d In the Introduction section, the authors also described the first few possible UK variant cases in Romania.Are these 20 cases sequenced by authors related to those cases mentioned in the Introduction? If not, can authors provide some details about the subjects' past travel history? For example, did they stay in UK for more than 2 weeks before they traveled to Romania? And when were these samples collected? The timeline is important to understand how the disease spread and whether they are the first strains of B.1.1.7 in Romania.Response: We thank the reviewer [reviewer  for his/The other four samples presented in the Results section were sequenced by other laboratories in the country, so there is no connection with the 20 samples sequenced by us.Information regarding the travel history of the patients was added, where appropriate. Sample collection dates were added to the table in Multimedia Appendix 1.2. The authors claimed that \u201cthe Romanian strains bearing the particular ORF8 mutations described above clearly originated in the UK, which is also supported by the fact that the patient from Suceava county arrived in Romania from the UK.\u201d I have a similar question about the travel details of the patient as well as the timeline.Response: Information regarding the Romanian patient bearing the ORF8 mutation was added in the Results section.3. From a public health standpoint, how did the authors deal with the \u201cnews\u201d of the new variant? Was there any communication with local officials or support for contact tracing?Response: This information was added to the text. In addition, we mentioned that our laboratory is 1 of 4 (at the moment of writing the paper) that reports weekly genomic data to government agencies. These data are then integrated with epidemiological data to inform public health agencies.4. In the Discussion section, the authors described that \u201cMany European countries, including Romania, lag in genomic sequencing\u201d. Can the authors provide more details about why Romania lags in genomic sequencing for COVID? For example, cost, equipment, access to labs/institutes. This can help readers and other researchers to understand the issue.Response: The information was added to the text."}
{"text": "A further independent investigation conducted in the Editorial Office revealed that other western blotting data were likely to have been shared in common, comparing between the two articles.Oncology Reports, the Editor has decided that this paper should be retracted from the Journal. After having been in contact with the authors, it was admitted that the authors Feng Chang, Jian-Na Liu and Jun-Xin Lin did not initially provide their agreement to be authors on this paper; otherwise, the rest of the authors accepted the decision to retract the paper. The Editor apologizes to the readership for any inconvenience caused.Owing to the fact that the contentious data in the above article had already been submitted for publication prior to the submission of this article to"}
{"text": "Following an institutional investigation by the University of Sargodha, the authors regret the omission of Tahir Mehmood in the original author list.The correct authorship list and affiliations list is displayed herein. The updated acknowledgements and author contributions are shown below.Conceptualization, Aliya Ajaz and Muhammad Ashraf Shaheen; methodology, Muhammad Ashraf Shaheen, Aliya Ajaz, Abu Bakar Siddique; software, Maqsood Ahmed; data collection, structure solution, refinement, validation, Khurram Shahzad Munawar, Muhammad Fayyaz ur Rehman and Abdul Karim; formal analysis, Nazir Ahmad; investigation, Abdul Karim; resources, Muhammad Ashraf Shaheen; data curation, Aliya Ajaz; writing\u2014original draft preparation, Aliya Ajaz; writing\u2014review and editing, Abu Bakar Siddique; visualization, Muhammad Fayyaz ur Rehman; supervision, Muhammad Ashraf Shaheen, Tahir Mehmood; project administration, Muhammad Ashraf Shaheen. All authors have read and agreed to the published version of the manuscript.We are thankful to the Higher Education Commission of Pakistan (HEC) for providing financial assistance to PhD Scholar (Aliya Ajaz) to conduct a part of her research work in the United States under the International Research Support Initiative Program (IRSIP).The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Retraction Note: BMC Cancer 19, 224 (2019)10.1186/s12885-019-5419-5The Editors have retracted this article because of significant concerns with a number of figures, specifically:Figure\u00a07d, CD133 panel, appears to be the same as Fig.\u00a02D, Oct 4 panel, in [Figure\u00a04b, FAP-a panel, appears to be the same as Fig.\u00a03D, p53 panel, in Figure\u00a03a, b-actin panel, appears to be the same as Fig.\u00a03K, b-actin panel, in [The authors were contacted and asked for an explanation but did not provide one. The Editors therefore no longer have confidence in the integrity of the data in this article.Kai-qun Ren agrees with the retraction. None of the other authors have responded to any correspondence from the Editors about this retraction."}
{"text": "This article has been retracted: Aging has completed its investigation of this paper. We found multiple internal duplications and overlap between some of the transwell assay images used for Figures 3C,E and 5C,D,F and data published the preceding year by other authors [ authors . The aut"}
{"text": "Jirun Sun was not included as an author in the original publication . The corAuthor Contributions: Conceptualization, X.W., S.Y. and J.S.; methodology, S.Y. and J.S.; validation, X.W.; formal analysis, X.W.; investigation, X.W.; resources, X.W. and J.S.; data curation, X.W.; writing\u2014original draft preparation, X.W.; writing\u2014review and editing, X.W. and S.Y.; visualization, X.W. All authors have read and agreed to the published version of the manuscript.In the original publication, the funder, NIH, grant number DE023752 to Jirun Sun, was not included. The updated funding section appears here. Funding: This research was funded by NIH, grant number DE023752.In addition to affiliations 1 and 2, the updated affiliations should include the following:3 The Forsyth Institute, Cambridge, MA 02142, USA4 Harvard School of Dental Medicine, Boston, MA 02115, USAThe authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated."}
{"text": "Figure 3E and F and Fig. 8C and D were omitted from the HTML version, although they do appear in the PDF version. The missing panels should appear as shown below.Volume 9, no. 1, e00496-21, 2021,"}
{"text": "Signal Transduction and Targeted Therapy 10.1038/s41392-019-0082-5, published online 06 December 2019Retraction to: Figs. 2f and 3f (HUH-7 Scramble) appear to contain an overlapping area.HepG2 Scramble in Fig. 2d and HUH-7 LV-DKK1 in Fig. 3d appear to be mirror images.A part of the HUH7 Scramble image in Fig. 2d appears to be enlarged and presented as HepG2 Scramble.The authors therefore no longer have confidence in the presented data.The authors have retracted this article. After publication, concerns were raised regarding suspected overlap in the cell images in Figs. 2 and 3. Specifically:All authors agree to this retraction."}
{"text": "In our original paper, in theAcknowledgments section, one sentence is missing. The complete Acknowledgmentssection is below. This correction does not affect any of the resultsof the work."}
{"text": "Commentary: Computational Analysis for ERAS and Other Surgical Processes: Commentary From Clinical Perspective By Mills H, Acquah R, Tang N, Cheung L, Klenk S, Glassen R, Pirson M, Albert A, Hoang DT and Van TN (2022). Front. Surg. 9:946963. doi: 10.3389/fsurg.2022.946963.A Retraction of the Original Research Article Following publication, the publisher uncovered evidence that several false identities were listed as authors for this article. During this investigation, the publisher was unable to confirm the institutions of the authors Hilla Mills, Ronald Glassen, Susanne Klenk, Nova Tang, or Luke Cheung. This investigation was conducted in accordance with Frontiers' policies and the Committee on Publication Ethics (COPE) guidelines.The investigation also uncovered concerns about the presentation and validity of the data in the article.This retraction was approved by the Chief Editors of Frontiers in Surgery and the Chief Executive Editor of Frontiers.The authors did not respond to contact regarding this retraction."}
{"text": "This article has been retracted at the request\u00a0of the authors due to a miscommunication resulting in the failure to obtain\u00a0proper ethics review from Shiga University of Medical Science. The authors did obtain ethical review and approval from\u00a0Seijo University and were under the impression that ethical review from Shiga University of Medical Science was not required. Once informed of their error, the authors contacted the Shiga University of Medical Science ethics committee in an attempt to receive retrospective ethical review\u00a0and approval, however this request was denied. As a result, the authors have regretfully requested this retraction. After a thorough review, the journal has agreed and the article has been retracted."}
{"text": "The Royal Society of Chemistry is publishing this expression of concern in order to alert readers that concerns have been raised regarding the reliability of the EDX data in Fig. 2b. An investigation is underway, and an Expression of Concern will continue to be associated with the article until a final outcome is reached.Laura Fisher2nd November 2023RSC AdvancesExecutive Editor,"}
{"text": "In Figs"}
{"text": "What conflicts of interests or financial disclosures are reported by physician guideline authors serving on guideline committees of the American Association of Ophthalmology (AAO) relative to payments reported by industry on the US Centers for Medicare & Medicaid Open Payments database?In this cross-sectional study, among 149 physician guideline authors who declared having no financial disclosures while serving on the AAO guideline committee, 81 physician authors (54.4%) had payments indicated by industry on the Open Payments database not reported within the guidelines.Discordance in disclosures of physician authors serving on AAO guideline committees should be evaluated to strive for accurate disclosures. This cross-sectional study assesses financial disclosures reported by physician authors of the American Academy of Ophthalmology (AAO) Practice Pattern Guidelines compared with those reported by industry to evaluate the disclosures\u2019 accuracy. Recommendations of clinical guidelines affect physicians\u2019 care delivery. Potential bias and undeclared conflicts of interests (COIs) among guideline authors can impact clinical practice decisions.To assess financial disclosures reported by physician authors of the American Academy of Ophthalmology (AAO) Practice Pattern Guidelines compared with those reported by industry to evaluate the disclosures\u2019 accuracy.In this cross-sectional study, all clinical guidelines in the AAO Preferred Practice Patterns (PPP) since 2013 (first year with publicly available industry payment reports) were reviewed on May 1, 2022. Guideline physician authors\u2019 name and their reported COI disclosure were extracted from the guideline publication. Payments to physician authors reported by industry were retrieved from the US Centers for Medicare & Medicaid Open Payments database. Physician authors serving on the AAO guideline committee were included.The primary outcome measure was the accuracy of authors\u2019 COIs disclosure. Secondary outcome measures were payments to physician authors reported by industry, the types of payments, and authors\u2019 gender.P\u2009=\u2009.003).A total of 24 AAO guidelines released between 2016 and 2020 were included. Per guideline, there was a mean (SD) of 7.83 (2.24) physician authors. After removing 14 nonphysician authors, 188 physician author names remained, including 83 names assigned as women (44.1%) and 105 names assigned as men (55.9%). Authors could be counted multiple times in these 188 names. According to the Open Payments database, industry reported that 112 of 188 physician authors (59.6%) had at least received 1 payment while serving on the guideline committee, with a payment mean (SD) of $29\u2009849.35 ($54\u2009131.56). According to AAO guidelines, 149 authors (79.3%) had no financial disclosures while serving on the guideline committee. Among these 149 authors, most authors (81 [54.4%]) had payments reported by industry on the Open Payments database not disclosed within the guideline reports. Women physicians were paid significantly more than men for total payments (median [IQR] payments, $15\u2009265 [$598.47-$41\u2009104.67] vs $301.48 [$218.85-$14\u2009615.09]; difference, $14 963.52; Industry reported physician guideline authors to have received significant industry payments, some of which were not disclosed within information of the guidelines. To strengthen author transparency regarding these reported disclosures, the authors may want to review and resolve such potential discrepancies during the review and subsequent publication of guidelines. Some companies also need to report their physicians\u2019 ownership and investment interests.3 To ensure transparency, the information is centralized on the US Centers for Medicare & Medicaid Open Payments database, a public website.4Rooted in evidence-based medicine, clinical practice guidelines (CPGs) use available scientific data to provide the latest recommendations with the goal of optimizing patient care.6 Readers should thus be aware of physician authors\u2019 potential COIs. To our knowledge, the extent to which COIs systematically bias the field of ophthalmology by influencing society guidelines and the accuracy of COIs reported by authors of guidelines or reported by industry to have been given to those authors is unknown.Financial compensation can compromise medical research by skewing study outcomes and physicians\u2019 clinical decisions.7 We further determined author gender  to evaluate potential differences in COIs.Considering this gap in the ophthalmology literature, we assessed payments reported by authors of the American Academy of Ophthalmology (AAO) Practice Pattern Guidelines compared with payments reported by industry to have been given to these authors to evaluate the disclosures\u2019 accuracy and authors\u2019 compliance to the Council of Medical Specialty Societies\u2019 Code for Interactions with Companies.8 and reviewed available industry payment data listed from the Open Payments database4 on May 1, 2022. The study period was determined based on publicly available industry payment data only being reported as of 2013. Indeed, the national policies mandating Open Payments were originally enacted in 2013 with the goal of collecting and publishing information about payments reporting entities made to covered recipients.9 This study was exempt from research ethics board review per Article 2.2 of the Tri-Council Policy Statement. The described research adhered to the tenets of the Declaration of Helsinki. This study followed the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) reporting guideline.All authors reviewed all clinical guidelines in the Preferred Practice Patterns (PPP) section of the AAO websiteTwo authors (A. X.-L. N. and M. J.-C.) retrieved guideline authors\u2019 names and their reported COI disclosures on the guideline publication. Guideline authors only included guideline writers. Nonphysician guideline authors were excluded. We further documented if the authors were chairs or cochairs of the AAO subspecialty guidelines committee. The exact dates in which physician authors joined AAO\u2019s guidelines committees were unknown. Physician authors were counted multiple times if they authored more than 1 AAO guideline.Three authors  entered eligible authors\u2019 names into the Open Payments search tool and cross-matched their full name, role , medical specialty , and location to identify the correct individuals and extract their payment data matching the disclosure period indicated on the AAO guideline. Indeed, the AAO guidelines provide specific disclosure periods by indicating months and years. For example, if a guideline has a disclosure period from January to October 2019, we matched the same time period on Open Payments.9 One of us (A. X.-L. N.) determined physician authors\u2019 gender  by inputting their first names into Gender API,10 which is an application program interface assigning gender with 98% accuracy.11Payment data were categorized into general payments, research payments, research funding, and ownerships. General payments are payments not associated with research studies, contrary to research payments. Examples of general payments include consulting and speaking fees, honoraria, gifts, and royalties not related to research studies. Associated research funding is defined as funding received for a research project where the physician is named as principal investigator. Ownership payments consist of the actual dollar amount invested and the value of the ownership or payment investment interest.P values were not adjusted for multiple analyses. P values less than .05 were considered statistically significant, and all P values were 2-tailed.Descriptive statistics were calculated using Stata/IC version 16.1 (StataCorp). The Kruskal-Wallis test by ranks was performed to test whether there was a significant difference in median total payments between men and women. A total of 24 guidelines released between 2016 and 2020 by the AAO were included. PPPs were divided into subspecialty , includiThere were 14 nonphysician author names, including 2 assigned as women and 12 assigned as men. These nonphysician authors wrote between 1 and 7 guidelines each and held one of the following degrees: CO, COMT, JD, MHS, MPH, PhD, or ScM. After excluding 14 nonphysician author names, 188 author names remained, including 83 assigned as women (44.1%) and 105 assigned as men (55.9%). These author names represented 66 different authors, as authors wrote between 1 and 8 guidelines each. According to the AAO guidelines, 149 guideline authors (79.3%) had no financial disclosures while serving on the AAO guideline committee.Among the 149 guideline authors who reported having no financial disclosures, 81 (54.4%) had payments reported by industry on the Open Payments database while serving on the AAO guideline committee. More specifically, guideline authors with no financial disclosures reported on the guidelines had the following payments reported by industry on the Open Payments Database during the AAO disclosure period: a median  of 5  payments and a mean (SD) of 8.2 (13.8) payments, totaling between $9.78 and $79\u2009602.07 . A total of 16 guideline authors (19.8%) had payments of less than $100 reported by industry on the Open Payments database.According to the Open Payments database, 112 of 188 physician authors (59.6%) had been reported by industry to have received at least 1 payment while serving on the AAO guideline committee ; Figure.P\u2009=\u2009.003).As indicated in There was a total of 30 physician authors serving as chairs and cochairs in the AAO guidelines reviewed, with 6 guidelines cochaired by 2 physicians. A total of 6 of 30 chairs and cochairs (20%) reported financial disclosures in the AAO guidelines. Of these, 21 chairs and cochairs had financial disclosures reported by industry on the Open Payments database, with 1 to 115 payments  totaling $61.56 to $79\u2009602.07 .5 The payments reported by industry to have been received by physician authors of AAO guidelines was substantial, with a median (IQR) of $691.17 ($218.85-$41\u2009104.67) and a mean (SD) of $29\u2009849.35 ($54\u2009131.56), which is higher compared with industry payments received by clinical guideline physician authors in other medical specialties.14 All authors reviewed all AAO guidelines published from 2013 until May 2022, and 2 authors (A. X.-L. N. and M. J.-C.) extracted physician guideline authors\u2019 COIs. Three authors  retrieved physician payments reported by industry using the Open Payments database.Some ophthalmologists are reported by industry to receive substantial payments from industry on the Open Payments database.15 However, more than half of physician authors (81 [54.4%]) who declared having no financial disclosures while serving on the AAO guideline committee had payments reported by industry on the Open Payments database. Studies in other medical specialties that examined physicians who authored clinical guidelines of leading specialty organizations similarly reported a disconnect between the COIs reported in the guidelines and those reported by industry in Open Payment systems.14 If truly representing errors, this disconnect between COIs reported in guidelines and in Open Payments may contribute to potential biases in guidelines of national medical organizations, including the AAO.2 Furthermore, the Institutes of Medicine Guidelines for trustworthy CPGs recommends that 50% or more authors on CPG committees have no COIs.16 While nominally all the AAO guidelines fit this criterion, our analyses show that 16 of 24 guidelines now fail and may be considered untrustworthy. Additionally, these best practice guidelines for CPGs recommend that committee chairs have no COIs, which is not the case in 6 of 30 chairs and cochairs based on the AAO guidelines\u2019 own disclosures and in 21 of these same chairs and cochairs based on the information reported by industry on the Open Payments database.AAO\u2019s policy statement stipulated that committee members must disclose all financial relationships with companies.P\u2009=\u2009.003). Our findings differ from prior studies reporting that women physicians were underrepresented in industry compensation and paid less in industry partnerships compared with men.18 Extended research should be conducted to understand these financial differences.Among the 112 physician authors who were reported by industry to have received at least 1 industry payment, women (54.5%) were more represented than men. Women physicians were reported by industry to have been paid significantly more than men for total payments  using Gender API. Gender API does not capture the spectrum of gender identities, which limits genders included in this study.Our study presents limitations. The first limitation is that we are using the Open Payments database. Therefore, we are relying on payments reported by industry, which do not necessarily indicate payments truly received by physicians. Indeed, Open Payments could have reporting errors from a company; some listings in Open Payments may have gone to a physician\u2019s employer or a payment declined by a physician still could be reported in Open Payments system. Second, the SDs calculated for the payments reported to have been received indicate that the data are quite skewed, as they are 2-fold greater than the means. It is also not possible to fully assess ophthalmologist\u2019s financial disclosures due to the limits of the Physician Payment Sunshine Act. The Sunshine Act only requires payment reporting of companies that sell products covered by government programs and that offer compensation worth more than $10.19Moving forward, AAO policies could be modified by reinforcing authors\u2019 reviews of their disclosures with disclosures reported by industry on the Open Payments database. Increasing authors\u2019 awareness and understanding of the AAO policy statement may also contribute to better declaration of COIs in clinical guidelines. It remains unclear if COI reporting alone is sufficient to mitigate industry influence on evidence-based guidelines."}
{"text": "The authors regret the omission of the funding acknowledgements in the original article. These acknowledgements are given here.This work was financially supported by the Key Research Program of Zhejiang Province (2021C02041 and 2021C02013), the National Natural Science Foundation of China (32201238), the \u201cSannongjiufang\u201d Research Joint Project of Zhejiang Province in 2022 (2022SNJF059) and the \u201cSannongliufang\u201d Research Joint Project of Zhejiang Province in 2021 (2021SNLF008).The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "The authors of the original article \u201cYanghe Huayan Decoction inhibit the capability of trans-endothelium and angiogenesis of HER2+ breast cancer via pAkt signaling\u201d (DOI: 10.1042/BSR20181260) would like to correct After publication the authors identified that the data had been incorrectly calculated, the current result could not be generated from the raw data and that the title for the Histogram was incorrect.In addition, the following text from the first paragraph of the Results section: The data indicated that YHD significantly inhibited cells crossing through HUVEC-plated upper chamber by 61.15% , and the inhibition of combination was the most effective  .Should instead read: The data indicated that YHD significantly inhibited cells crossing through HUVEC-plated upper chamber by 56.70% , and the inhibition of combination was the most effective . However, there was no obvious difference of tans-endothelium capability between YHD and trastuzumab groups  .The requested correction has been assessed and agreed by the Editorial Board. The authors declare that these corrections do not change the results or conclusions of their paper."}
{"text": "M., Varela, S., Mart\u00ednez Cortizas, A. M., & Fragoso, J. M. V. (2023). Mammal traits and soil biogeochemistry: Functional diversity relates to composition of soil organic matter. Ecology and Evolution, 13, e10392. sobral.bernal.mar@gmail.com\u201d was incorrect. This should have read: \u201cmar.sobral.bernal@usc.es\u201d.In the correspondence data of the \u201cAuthors' list\u201d section, the email address \u201cWe apologize for this error."}
{"text": "Retraction Note: Orphanet Journal of Rare Diseases (2022) 17:6410.1186/s13023-022-02221-zThe Editor-in-Chief has retracted this article after the authors discovered 14 data calculation errors in Table\u00a01. The authors have been invited to submit a new manuscript for peer review. Kaiyue Hu disagrees with this retraction. None of the other authors has responded to correspondence from the Publisher about this retraction."}
{"text": "The present international eminence-based study, harmonizing diverse intercultural perspectives, highlighted the specific needs of older judo practitioners. The results of this study will contribute to the structure of a sound educational program for coaches of older judo practitioners to enhance the quality of older adults\u2019 sports experiences by linking safety, enjoyment, social interactions, and learning principles.Judo coaches are urged to develop specific competencies and skills for addressing the special needs of older practitioners. Thus, the purpose of this study was to investigate the experts\u2019 opinions on judo training in late adulthood to develop sound educational programs for coaches of older judo practitioners. Overall, eighty-eight experts from an international consortium of judo and educational partners participated in national focus groups. During the focus groups, experts discussed five themes and generated statements pertinent to educate coaches to support older judo practitioners . The initial list of 262 statements was synthesized, validated, analyzed, and organized into a final list of 55 statements and six macro-areas: aging process ( Healthy aging has become a high priority in contemporary society, also considering the relevant and continuous increase of the older adults\u2019 share in the general population . Thus, tJudo  is a martial art and an Olympic combat sport, but more a means of education and a method of personal and social improvement through the execution of various techniques, according to its founder, the Japanese educator Jigoro Kano Sensei. Due to its inner characteristics stimulating coordination, dynamic balance, bone health, and mental control, judo has been considered particularly suitable for older people ,20,21,22https://academy.ijf.org/ (accessed on 19 July 2023)). To gain a comprehensive understanding of the benefits of judo in older adults and to assist coaches in effectively promoting judo training in healthy settings, the European Commission recently funded the \u201cEDucating Judo Coaches for Older practitioners (EdJCO)\u201d Project (622155-EPP-1-2020-1-IT-SPO-SCP) under the Erasmus+ Sport Programme [Coaches\u2019 preparedness is a crucial component for structuring and monitoring safe and effective sports programs for older individuals . In thisrogramme ,29. The rogramme .Therefore, the purpose of the present eminence-based study was to explore experts\u2019 perceptions regarding the knowledge and competencies that judo coaches should acquire to plan safe judo training for older individuals. In particular, the focus group methodology was deemed appropriate to explore the opinions of academic and judo experts on the necessary knowledge to be provided to coaches on the benefits, the risks, and the adapted judo methodologies for implementing effective and safe programs for novice and expert older judo practitioners . It was The present study was approved by the European Commission (622155-EPP-1-2020-1-IT-SPO-SCP) and the Institutional Review Board of the University of Rome Foro Italico (CAR73/2021). An ethnographic research approach was deemed appropriate to construct an international educational programme for judo coaches encompassing educational units and intelligible content according to the needs of coaches from different social and cultural settings . To gathWhat are the most relevant benefits judo coaches should be aware of when training former or novice older judo practitioners?What are the most relevant information judo coaches should be aware of when training novice older judo practitioners?What are the most relevant information judo coaches should be aware of to prevent/manage risks when training former or novice older judo practitioners?Which are the main criteria for defining judo training groups in relation to participants\u2019 judo expertise, chronological/functional age, and/or sex?What are the most relevant tools/tests/measurements for monitoring training plans for former or novice older judo practitioners?Following the findings of a systematic literature review , the resOverall, this study met the eight criteria for qualitative excellence ,38: (1) According to the literature  and in aBetween May and October 2021, seven focus groups were organized in presence and online according to the current COVID-19 pandemic national-specific regulations in Croatia, Italy, Malta, Romania, Slovenia, Spain, and T\u00fcrkiye. The common structure of the focus groups encompassed four phases, with an overall average duration of around 100 min . First, The statements recorded during each national focus group in relation to the five proposed open-ended questions have been recorded in the respective seven national languages. The translation guidelines encompassed a faithful preliminary translation of each statement into English, which was independently performed by two components of the research group from each country. Then, to ensure the accuracy of the English translation, an English reviewer was involved in a blind-back translation procedure. Thus, the final list of the English version of the statements in relation to the five open-ended questions was achieved. The procedures to analyze the collected data have been consistent with the original purpose of the study and the need to generate eminence-based knowledge in relation to the research questions for the identification of judo coaches\u2019 educational needs in implementing training programs for older adults . To harmOverall, eighty-eight experts provided their written informed consent to volunteer for this study . The initial list of 262 statements was synthesized, validated, analyzed, and organized into a final list of 55 statements and six macro-areas and sub-groups . AccordiThe present study\u2019s novelty lies in experts\u2019 contribution to uncovering the relevant knowledge coaches need to acquire to coach safely and effectively older judo practitioners. According to the experts, aging processes , first aid , individual motor literacy and functional fitness, assessment tools, and evaluations, psychological , organizational  and technical  aspects emerged as the main needs of education of judo coaches. The conceptualization of essential contents for judo educational curricula is crucial for helping coaches understand the objectives of judo programs for older adults and the necessary knowledge of practitioners\u2019 health, abilities, and potentials, and recognizing the problems older judo practitioners may encounter. This aspect is particularly relevant in considering that coaching education has almost exclusively focused on youth, adolescent, and young adult athletes . EngaginThe experts highlighted the necessity to raise the awareness of judo coaches on the aging process, which is characterized by pronounced differences between individuals due to a multi-factorial model where a natural devolution of physiological and functional abilities, high exposure to chronic diseases, and reduced active lifestyles mutually influence each other, resulting in a high incidence of chronic diseases and long-term consequences on health ,46. AccoAlthough exercise training is a recommended non-pharmacological treatment for individuals with hypertension and other coronary diseases, exercise modality elicits different effects during and after the training session, also in relation to the training status of the practitioner ,63,64,65In relation to safety and first aid aspects, during the focus groups, the experts specifically addressed the necessity to require a family medicine or a sports medicine certification that includes general health, cardio-pulmonary, metabolic, and musculoskeletal assessments. In countries where sports medicine certification is not mandatory, judo coaches could administer AAHPERD Council on Aging and Adult Development Medical/Exercise Assessment for Older Adults , which eIn this study, experts urged coaches to be aware of age-related dehydration, which could be due to physiological  and behavioral  factors. In fact, dehydration could negatively impact performance, cognitive functions, bronchoconstriction and related pathogenesis of certain pulmonary disorders, and vision ,82,83,84A thorough knowledge of the health status, previous injuries, and physical activity experience of every novice practitioner is crucial to adapt the judo training and techniques to the individual characteristics of the older judo practitioners and to ensure well-controlled interventions ,22,44. IIn this study, the experts emphasized the necessity of adopting strategies to increase older judo practitioners\u2019 self-confidence through self-development-based goals and an enjoyable environment in the dojo, which could increase their mental and psychological health. In fact, multimodal physical activity interventions over long periods, high functional fitness, and activity engagement are considered effective preventive measures for mental disorders affecting more than 20% of middle-aged and older adults presenting relevant disturbances in thinking, emotional regulation, anxiety, behavior control, dementia, depression, and Alzheimer\u2019s diseases ,102,103.The experts claimed that fears  and anxiety disorders could be potential obstacles for older practitioners to engage in judo training, and suggested that a practitioner-based approach rather than traditional and/or conventional training protocols should be adopted ,109,110.Regarding organizational and environmental aspects, during the focus groups, the expert emphasized the role of the family, friends, and group relationships in supporting the engagement in judo of older practitioners, as well as in decreasing the social isolation, loneliness, and depression, which increase with advancing age ,115. To According to the expert\u2019s opinions, coaches have to apply specific strategies and methodologies to achieve positive outcomes  from an adapted judo training ,22,111. It is well known that falls account for the second leading cause of unintentional injury and deaths worldwide . TraininExperts also highlighted the necessity that coaches should guide practitioners with clear and simple communication to avoid deleterious misunderstandings that can generate incorrect or dangerous executions. Furthermore, to facilitate the learning of judo techniques while preserving the safety of the older practitioners, coaches are encouraged to use mats, exercise balls, balance boards, and resistance bands, also using background music, which could correspond to the requirements for the organization of learning and training processes in judo . AnotherThe present work was the first EU-funded collaborative partnership addressing the issues of educating coaches for older judo practitioners. In complementing the evidence-based knowledge on judo training in older practitioners, the present participatory approach provides multidisciplinary experts\u2019 experiences and opinions to be considered in the construction of an educational program for judo coaches of older adults. To improve the usability and satisfaction of a sound educational program for the implementation of competencies of judo coaches with respect to older practitioners, a major limitation is still present. In fact, there is a need for further investigations to provide empirical validation of relevant necessary competencies coaches should possess when training older judo practitioners. Actually, structured and comprehensive education for coaches of individuals with advancing age is still limited . TherefoThe present international eminence-based study investigated the expert\u2019s perspectives regarding the necessity of a tailored education for judo coaches of older practitioners, harmonizing diverse intercultural perspectives. The experts addressed the major needs of coaches\u2019 education, including the most relevant age-related chronic diseases, psychological  and health  aspects that characterize the aging process, the needs of risk prevention and emergency action plans, the adapted techniques to meet the functional fitness and motor literacy of older practitioners, the evaluation tools, and the organisational  arrangements. In fact, the role of judo coaches is crucial when addressing the multifaced challenges of providing adequate training programs to a heterogenous older adult population . Thus, to apply a practitioner-based approach and promote active, healthy aging, a trustful and empathic relationship between judo coaches and practitioners is a milestone.To propose judo coaches as a user-friendly tool to facilitate a sound practitioner\u2019s self-development program, our work introduces novel guidelines to promote judo lifelong learning for older people. Due to falls-related injuries, older people are facing disabilities and psychological diseases . In this respect, judo could prevent fall-related injuries by engaging older people in a person-centered approach to learning judo breakfall techniques . Thus, j"}
{"text": "This is a peer review submitted for the paper \"COVID-19 and Cybersecurity: Finally, an Opportunity to Disrupt?\"The contribution \u201cCOVID-19 and Cybersecurity: Finally, an Opportunity to Disrupt?\u201d [Unfortunately, the contribution is not in the general JMIR style, which needs to be checked by the editor.To summarize, there is nothing new in this article that has not been reflected in the general news media. Even for a Viewpoint, the technical references are completely missing. In the end, I do not see any value in this well-written but technically weak viewpoint.The authors present their viewpoint, but all points are more or less mainstream. What is the \u201cnew message,\u201d what is different from all the others?Several points have technical backgrounds, which do not need to be described in a viewpoint article; however, the authors need to show that they are familiar with the literature in the mobile health cybersecurity domain. I do not see this point, and it needs strengthening.When it comes to contact tracing apps, the presentation is rather weak, and several questions or facts are not resolved . There are a lot of concepts in different countries for tracing apps; the authors do not describe these. In some countries, the reaction to a warning is left to the user, but what happens if larger groups disobey the warnings of tracing apps?One argument has not been presented, namely that the increased use of electronic equipment in social distancing times increases the cybersecurity attack surface.In the section on data sharing, the potential of false positives needs to be discussed, eg, technical limitations of distance estimations between different smartphone types should be critically reflected and a reference to this discussion should be given.The authors do not reflect on the general cybersecurity risks of implemented mobile health apps .There are some reflections on difficulties for tracing apps, but they are not backed by references.The title is very general, and the content does not fit the title; it needs to be less general and has to reflect that this is not a technical paper but a Viewpoint.This paper is improved, but I am not convinced about the content, which is noncomprehensive and not novel (which has been well explained by the authors). There is no typical research method behind it, such as a scoping review or similar, which may be the reason that I do not like it. In my opinion, the world does not need such a viewpoint paper, but the editors have to decide."}
{"text": "J Cell Mol Med. 2019; 23: 7709\u20137716. The above article, published online on 26 September 2019 on Wiley Online Library (https://onlinelibrary.wiley.com/doi/full/10.1111/jcmm.14644), has been retracted by agreement between the journal Editor\u2010in\u2010Chief, Stefan Constantinescu and John Wiley & Sons Ltd.Pu Li, Qiaoge Zhang and Hua Tang. The retraction has been agreed following an investigation based on allegations raised by a third party, indicating irregularities in figure panels for manuscripts in multiple journals. Irregularities and concerns were found in Figures 2D, 2E, 4C and 4D involving eight images in the article. The authors confirmed the errors. Raw data underlying these figure panels were no longer available and as a result, the journal cannot independently verify the conclusions of the article. The authors were contacted regarding the findings and the proposed retraction, but we did not receive a response."}
{"text": "The journal retracts the article \u201cValidation of the CHA2DS2-VA Score  in Nonvalvular Atrial Fibrillation Patients: A Nationwide Population-Based Study\u201d . Following publication, methodological and data interpretation concerns were brought to the attention of the Editorial Office.Adhering to our complaints procedure, an investigation was conducted by the Editorial Office and Editorial Board that confirmed the presence of a number of significant issues with the methods used and the analysis of the data and concluded that the overall findings of this study  could noJournal of Clinical Medicine. This retraction was approved by the Editor in Chief of the The authors agreed to this retraction."}
{"text": "The authors hypothesize that the phenotype may have been due to the variable nature of the filamentation assay.In addition, the authors have been unable to reproduce the finding that In light of these issues, the authors retract this article.All authors agreed with the retraction. We apologize that these issues were not identified before the article was published."}
{"text": "In the original publication , there wThere were two figure numbers that were writing mistakes in Sections 2.3 and 2.4. The authors have replaced \u201cthere was no alteration in the NaHS treatment group \u201d with \u201cthere was no alteration in the NaHS treatment group \u201d in Section 2.3. And the authors replaced \u201cFigures 3J and 4H\u201d with \u201cFigures 3I and 4H\u201d in Section 2.4.The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original article has been updated."}
{"text": "This article was published without appropriate declaration of competing interest or patient consent statements.The publisher apologizes for any inconvenience caused by this mistake. The relevant statements are provided below.Declaration of Competing InterestThe authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.Patient consentThe authors have written informed consent from the patient for the publication of this case report."}
{"text": "Retraction Note: J Exp Clin Cancer Res 37, 52 (2018)10.1186/s13046-018-0677-7The Editor-in-Chief has retracted this article. After publication, concerns were raised regarding highly similar images in the present figures, specifically:The Transwell assay images in Fig.\u00a06e and f, and 7i appear to contain multiple overlapping panels;A number of images in Fig.\u00a06e appear highly similar to those in Figs.\u00a04d and 5d in the authors\u2019 earlier article .Figure\u00a07h middle panel p-Akt lanes 3 and 4 appear highly similar to Fig.\u00a07k right panel N-Cad lanes 1 and 2.Figure\u00a07h left and right panel b-actin blots appear highly similar to those in Fig.\u00a07k, but the middle panel blots are different.Additionally, the study used Bel7402 and Bel/5-FU cell lines, which have both been reported to be HeLa derivatives. Therefore, these cells are not suitable models for hepatocellular carcinoma.The authors have provided the raw data from the Transwell, immunohistochemistry and western blot assays. However, further checks by the publisher found labelling errors in the original western blot data that may have affected the results and conclusions of the article. The Editor-in-Chief therefore no longer has confidence in the presented data.Corresponding Author Tao Tian has stated on behalf of all co-authors that they do not agree to this retraction."}
{"text": "More specifically, there was a printing mistake in . The corrected caption appears below: \u2018Effects of administration of C. osmophloeum leaf extract, nanoemulsion and powder in hydrosol on fasting blood glucose (FBG), oral glucose tolerance test (OGTT) serum insulin and HOMA-IR index in high-fat diet with streptozotocin injection into diabetic rats\u2019. The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated.In the original publication , there w"}
{"text": "Sci., 2023, 14, 7221\u20137229, https://doi.org/10.1039/D3SC00849E.Correction for \u2018Evidence for and evaluation of fluorine\u2013tellurium chalcogen bonding\u2019 by Robin Weiss  The authors regret that The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Retraction to: Bai et al. Gut Pathog (2020) 12:2210.1186/s13099-020-00361-w.The editors have retracted this article. After publication, concerns were raised regarding similarities of western blots, fluorescence images and flow cytometry plots presented in Figs.\u00a01, 2, 3, 4, 5, 6, 7 and 9 with other papers that were either published earlier or under consideration within a similar time frame [The authors have confirmed that incorrect images were used in this article, and the raw data are no longer available.The editors therefore no longer have confidence in the presented data.None of the authors have responded to any correspondence from the editor or publisher about this retraction notice."}
{"text": "Retraction Note: BMC Cancer 18, 641 (2018)https://doi.org/10.1186/s12885-018-4559-3The Editor has retracted this article. After publication, concerns were raised about the apparent overlap between panels H1975/shNC and H1993/shNC in Fig.\u00a02D. The authors sent raw data on request, where additional irregularities have been found, and the images for Fig.\u00a02D were different. The authors did not provide a sufficient explanation of the irregularities. The Editor has, therefore, lost confidence in the integrity of the findings. Xue Hou, Haoxian Yang and Li Zhang agree to this retraction. The Editor has been unable to obtain the current email addresses for Run Gong, Jianhua Zhan, Ting Zhou, Yuxiang Ma, Yuanyuan Zhao, Yaxiong Zhang, Gang Chen, Zhonghan Zhang, Shuxiang Ma, Xi Chen, Fangfang Gao, Shaodong Hong, Fan Luo, Wenfeng Fang, Yunpeng Yang, Yan Huang, and Likun Chen."}
{"text": "Open Biol.5, 150126. (Published online 1 December 2015). (doi:10.1098/rsob.150126)Following the publication of \u2018RNA editing of microRNA prevents RNA-induced silencing complex recognition of target mRNA\u2019, the Editorial team have concerns regarding the validity of the data used in this study.We are issuing an expression of concern here and investigating this as a matter of urgency; we will notify readers as to the results of our investigation as soon as possible."}
{"text": "PNAS Nexus, Volume 2, Issue 5, May 2023, pgad132, https://doi.org/10.1093/pnasnexus/pgad132This is a correction to: Eva Vriens, Luca Tummolini, Giulia Andrighetto, Vaccine-hesitant people misperceive the social norm of vaccination, PNAS Nexus, it was discovered that this paper was missing a statement acknowledging compliance with the PNAS Nexus Human and Animal Participants and Clinical Trials policy:During a retroactive audit conducted by Ethical approval was obtained from the ethical board of the Institute of Cognitive Sciences and Technologies of the Italian National Research Council (AMMCNT-CNR n. 0065527/2019). Participants in our studies were informed about the data collection, data storage, and their individual rights and provided informed consent before participating.This error has been corrected in the original article."}
{"text": "Open Med. (Wars) 2022 Dec 9;17(1):1949\u20131964. doi: 10.1515/med-2022-0584. PMID: 36561848; PMCID: PMC9743197, authors requested to replace In the published article Zhong Y, Zhang Z, Chen X. Inhibition of miR-21 improves pulmonary vascular responses in bronchopulmonary dysplasia by targeting the DDAH1/ADMA/NO pathway."}
{"text": "Vafaee et al., RSC Adv., 2021, 11, 22661\u201322676, https://doi.org/10.1039/D1RA02780H.Retraction of \u2018Synthesis and characterization of AFe RSC Advances article due to concerns with the reliability of the data.The Royal Society of Chemistry, with the agreement of the authors, hereby wholly retracts this 1 a new concern has been identified with the published article. The XRD patterns in Fig. 2b and both the original Fig. 4a and b contain multiple overlapping sections. In addition, new information brought to the attention of the Editor undermines the integrity of the authors' original explanation, meaning that the Editor has lost confidence that the findings presented in this paper are reliable.Following the publication of a previous correction to replace the XRD patterns in Fig 4a and b,Omid Amiri, Mansour Jahangiri, and Masoud Salavati-Niasari wish to state that they had no role in preparing the XRD data.1 related to this article.This retraction supersedes the information provided in the correctionSigned: Fahimeh Vafaee, Samira Mandizadeh, Omid Amiri, Mansour Jahangiri, Masoud Salavati-NiasariDate: 24/7/2023RSC AdvancesRetraction endorsed by Laura Fisher, Executive Editor,"}
{"text": "Adams, The Physiological Society and American Physiological Society, and John Wiley and Sons Ltd. The retraction has been agreed at the authors' request. Since publication, the authors have identified that the calculation of microcirculatory resistance does not require a correction factor. This invalidates several figures in the paper and the overall conclusions. The editors have no ethical concerns about the paper. The authors have prepared a Letter to the Editor (10.14814/phy2.15807) explaining, in detail, the error and their decision to retract the paper.The above article, published online on 10 March 2023 in Wiley Online Library ( Adams, The Physiological Society and American Physiological Society, and John Wiley and Sons Ltd. The retraction has been agreed at the authors' request. Since publication, the authors have identified that the calculation of microcirculatory resistance does not require a correction factor. This invalidates several figures in the paper and the overall conclusions. The editors have no ethical concerns about the paper. The authors have prepared a Letter to the Editor (10.14814/phy2.15807) explaining, in detail, the error and their decision to retract the paper.The above article, published online on 10 March 2023 in Wiley Online Library ("}
{"text": "Retraction Note: Journal of Hematology & Oncology (2020) 13:24 10.1186/s13045-020-00857-7The Editor-in-Chief has retracted this article. After publication, concerns were raised about image reuse in the article. Specifically:The top-left panel of Fig.\u00a02F was reproduced in two panels of Fig.\u00a04H, and in Fig. S11E of the supplementary materials.There is overlap between the top-left panel of Fig.\u00a02G and the second-from-top-right panel of Fig.\u00a04I.There is overlap between the top-left panel of Fig.\u00a04I and the bottom-left panel of Fig.\u00a05G.There is overlap between the second-from-bottom-left panel of Fig.\u00a04I and the top-right panel of Fig.\u00a05G.There is overlap between the bottom middle panel of Fig.\u00a05G and the bottom-right panel of Fig. S7B of the supplementary materials.Additionally, the top-left panel of Fig.\u00a02F was found to have previously been published in  by some Qiangsong Tong has stated on behalf of all authors that they do not agree to this retraction."}
{"text": "Food Science & Nutrition. https://doi.org/10.1002/fsn3.3006. The above article from Food Science & Nutrition, published online on 17 August 2022 in Wiley Online Library (https://wileyonlinelibrary.com), has been retracted by agreement between the journal's editor\u2010in\u2010chief, Y. Martin Lo, and Wiley Periodicals LLC. This action has been agreed upon due to image manipulation in Figures 1 and 4. As a result, the findings of this manuscript are considered unreliable. The editorial office did not receive responses from the authors or the institute.Retraction: Kou, Y., Zhu, R., Sun, Q., Li, Z., Feng, X., & Xu, H. (2022). Connexin 43 upregulation by dioscin\u2010inhibited gastric cancer metastasis by suppressing PI3K/Akt pathway."}
{"text": "Food Science & Nutrition, 2022 (https://onlinelibrary.wiley.com/doi/full/10.1002/fsn3.3107). The above article, published online on October 20, 2022 in Wiley Online Library (https://wileyonlinelibrary.com), has been retracted by agreement between the authors, the journal Editor in Chief Y. Martin Lo, and Wiley Periodicals LLC. The retraction has been agreed due to an error in which the incorrect manuscript was sent to the production team and published instead of the manuscript that the journal had reviewed and accepted.Effects of major ingredients  levels on physiochemical, rheological, and sensory attributes of walnut spread,"}
{"text": "Retraction Note : Clinical Epigenetics (2019) 11:173 10.1186/s13148-019-0763-5The Editors-in-Chief have retracted this article. After publication, concerns were raised regarding image similarities in the western blot and invasion assay data presented in the figures. Specifically:Fig. 5a H3K27me3 GL1 lanes 2 and 3 appear highly similar.Fig. 5b H3K27me3 lane 1 appears highly similar to lane 5.Fig. 7a and 9a appear to share the same beta-actin control blot.Fig. 9b U-87 MC4040 and MC4041 images appear to originate from the same sample, although the stated treatments are different.The authors have stated that the overlapping images in Fig. 9b were included by mistake. They have also provided partial raw data to address the western blot concerns; however, further checks by the Publisher have found that a number of western blot images presented in the article don't accurately represent the original data. The Editors-in-Chief therefore no longer have confidence in the presented data.Susanna Scarpa does not agree to this retraction. Giulia Stazi, Rossella Fioravanti, Manuela Sabatino, Rino Ragno, Samanta Taurone, Marcella Nebbioso, Raffaella Carletti, Marco Artico, Sergio Valente and Antonello Mai have not responded to any correspondence from the publisher about this retraction. The publisher has not been able to obtain current email addresses for Ludovica Taglieri, Alice Nicolai, Annalisa Romanelli and Stefania Morrone."}
{"text": "Corrigendum to: IC50: an unsuitable measure for large-sized prostate cancer spheroids in drug sensitivity evaluation .This corrigendum corrects the authorship information to: Yipeng Xu, Gabriela Pachnikova, He Wang, Yaoyao Wu, Dorothea Przybilla, Zihao Chen, Shaoxing Zhu, Ulrich Keilholz. At the request of Dr. Reinhold Sch\u00e4fer and with the agreement of all authors, Dr. Reinhold Sch\u00e4fer is excluded from the list of authors. Dr. Sch\u00e4fer expresses no doubts about the article's results and conclusion but was erroneously included on the list of authors.The authors sincerely apologize for the error and confirm that this correction does not change the conclusion of the article."}
{"text": "Retraction Note: Lipids in Health and Disease15, 172 (2016)10.1186/s12944-016-0332-2The authors have retracted this article. After publication, concerns were raised regarding the western blot data in Fig.\u00a04a. The authors have checked the original images and found duplication and labelling issues in the raw data. As the full-length gel images are no longer available, the authors are unable to verify the data and the reliability of the presented results.All authors agree to this retraction."}
{"text": "This publication was supported by the Cooperative Agreement Number 5 NU36OE000007-03, funded by the Centers for Disease Control and Prevention.In the publication \u201cEarly Refill of an Opioid Medication: Recognizing Personal Biases Through Clinical Vignettes and OSCEs,\u201d the following sentence should be added to the Funding/Support field:Additionally, the following field should be added:The contents of this publication are solely the responsibility of the authors and do not necessarily represent the official views of the Centers for Disease Control and Prevention or the Department of Health and Human Services."}
{"text": "Nucleic Acids Research, Volume 32, Issue 16, 15 August 2004, Pages 4893\u20134902, https://doi.org/10.1093/nar/gkh820The Editors were alerted in November 2022 that the JAR (c) and HeLa pLuc705 (c) panels depicted in Figure 5B show unusual levels of similarity.The experiments were conducted 20 years ago, and the authors no longer have the original data. The authors have retrieved and examined the submitted graphic files and agree that the two panels do indeed look very similar. The authors have provided an earlier figure, shown below, that was generated at a similar time from a replicate experiment. This figure confirms the results, namely that no significant fluorescence signal (cellular uptake) is observed for either cell type without Lipofectamine (LFA).The authors conclude that the same image must have inadvertently been inserted twice at revision.This error does not affect the results or conclusion of the article."}
{"text": "Sci., 2023, 14, 2336\u20132341, https://doi.org/10.1039/D2SC06553C.Correction for \u2018Abiotic microcompartments form when neighbouring droplets fuse: an electrochemiluminescence investigation\u2019 by Silvia Voci  The authors regret that their source of funding was not acknowledged in their paper. The authors acknowledge funding for this work from the National Institute of General Medical Sciences under Grant R35-GM138133.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "Ab initio study of the electronic states of V3Si in momentum space\u2019 by Saloni Sharma et al., RSC Adv., 2023, 13, 25836\u201325845, https://doi.org/10.1039/D3RA04535H.Correction for \u2018 The authors regret that there was an error in eqn (7). The correct equation is as shown below:The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers."}
{"text": "The authors would like to make the following corrections about the published paper . The cha8]s was written instead of the correct UD [(0\u00b0/90\u00b0)4]s. The corrected In Figure 11. Photomicrograph of a longitudinal section of a multi-scale structured contour joint with an inner [(\u00b170\u00b0)5] bandage. Photomicrograph provided by Fraunhofer IWU.Figure 12. Photomicrograph of a cross-section of a meso-structured contour joint without a [(\u00b170\u00b0)5] bandage. Photomicrograph provided by Fraunhofer IWU.There was a mistake in the captions for Figures 11 and 12. The use of externally provided images by Fraunhofer IWU was not mentioned. The correct figure captions appear below.Acknowledgments: The authors gratefully acknowledge the provision of photomicrograph images of the contour joint by Raik Gr\u00fctzner of the Fraunhofer Institute for Machine Tools and Forming Technology IWU.Raik Gr\u00fctzner (Fraunhofer Institute for Machine Tools and Forming Technology IWU) was not included as an author in the original publication. The added acknowledgements section appears here.The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. The above corrections were approved by the Academic Editor. The original publication has also been updated."}
{"text": "Retraction Note : Stem Cell Research & Therapy (2020) 11:204 10.1186/s13287-020-01705-8The authors have retracted this article. While trying to replicate this study they found that the polydatin could not recover the mRNA and protein expression of RUNX2, Osteopontin, DLX5, and OCN after lentivirus transfection. The authors believe that this could be due to contamination of lentivirus or the vector, or that polydatin was wrongly prepared in this study. All authors agree to this retraction."}
{"text": "In \u201cTechnology-Assisted Cognitive Motor Dual-Task Rehabilitation in Chronic Age-Related Conditions: Systematic Review\u201d  the authors noted one error:Affiliation of author Lorena Rossi:\u201cScientific Direction, Istituto Nazionale Riposo e Cura Per Anziani, Istituto di Ricovero e Cura a Carattere Scientifico, Ancona, Italy\u201dhas been replaced by:\u201cScientific Direction, IRCCS INRCA, Ancona, Italy\u201d.The correction will appear in the online version of the paper on the JMIR Publications website on September 26, 2023, together with the publication of this correction notice. Because this was made after submission to PubMed, PubMed Central, and other full-text repositories, the corrected article has also been resubmitted to those repositories."}
{"text": "This is a peer-review report submitted for the paper \u201cCOVID-19 Outcomes and Genomic Characterization of SARS-CoV-2 Isolated From Veterans in New England States: Retrospective Analysis.\u201dThe authors presented a study  about th1. Line 85: Authors wrote, \u201cwe recorded hospitalization status, mortality, and oxygen (O2)-requirement within 24 hours of admission.\u201d Here, can authors clarify if they recorded each single patient\u2019s clinical information within 24 hours of admission or they collected them from chart review? In addition, for O2, the 2 should be subscript.2. Lines 105 and 106: The disease name should be capitalized.3. Line 113: Authors did not provide a transition between the univariate regression and multivariate regression. Univariate analysis was simply mentioned in the first sentence without any explanation or discussion. Authors should indicate the reason why they conducted multivariate analysis . Additionally, in general, the factors should have the first letter capitalized, for example, Age, Non-White Race.4. Line 129: Authors wrote, \u201cour study found that in an older cohort of veterans.\u201d Here, older cohort could cause some confusion to some readers. When one reads the paper a few years later, he or she probably cannot understand what the older cohort is related to. Authors can add a time frame to it.5. Line 131: Similar to point 4, authors should add the Centers for Disease Control and Prevention (CDC) report date.6. Line 133: Authors wrote, \u201cveterans are a unique cohort because of advanced age on average, and more comorbidities. Understanding clinical factors that impact outcomes in veterans will help clinicians risk-stratify patients with similar demographic profiles.\u201d Many veterans could be young in some Veterans Affairs (VA) medical centers. It may be right to general veteran populations, but authors need to cite references to support this claim.7. Line 137: Authors wrote, \u201cin our study, age was a significant predictor for all of our outcomes and was a confounder for other variables.\u201d Most scientific papers are written from the third point of view. Therefore, it is not common to state the study outcomes as \u201cour outcome.\u201d Authors should use a better phrase, such as in line 151: \u201cThis may explain the outcomes in our study.\u201d8. Line 138: Authors wrote, \u201cinterestingly, LTC status predicted all three of our outcomes on univariate analysis, but not on multivariate analyses. Earlier in the COVID-19 pandemic, residents of nursing homes had higher rates of infection as well as severe illness and mortality .\u201d There 9. Line 140: Authors wrote that \u201cour study shows that among veterans in LTC facility, disease outcomes were not impacted by their residence status.\u201d Here, authors should provide some discussion or reasons for their findings.10. Line 148: Authors wrote, \u201cour study supports data from previous reports that non-White patients are at increased risk of hospitalization but have similar peak severity and mortality outcomes -6.\u201d Are 11. Line 156: Authors concluded that, for patients with dementia, they could have a high risk of death because of biological factors. Another possibility is the lack of self-report ability in patients with dementia. As a result, they probably do not understand their body\u2019s changes, which could delay the needed care.12. For the Discussion section, authors may add subtitles to different issues they would like to discuss. The current writing may be a little bit confusing to some readers.13. In the Discussion, the authors mentioned multivariate analysis of many potential risk factors as their strength. It is true that the multivariate model is a powerful tool, but it is not necessarily fit for the COVID-19 situation very well. Authors need to cite references about other cases of using the multivariate model for COVID-19 outcome analysis.14. Figures and supplemental tables: Authors should include more details in the titles. Simply writing \u201cgenomes\u201d or \u201chospitalization\u201d in the title is not standard in scientific papers.15. Figure 1: Authors should provide a better maximum likelihood tree. The current figure has many branches stacked to each other, barely providing any helpful information to readers.The authors presented an updated manuscript after taking the reviewers\u2019 suggestions. I have a few minor comments.1. Authors added reference  but did 2. Authors wrote, \u201cthis study included all veterans who tested positive for COVID-19 from April 8, 2020, to September 16, 2020 at one of the six New England VA hospitals.\u201d Previously authors wrote, \u201cConnecticut had been entrusted with testing for SARS-CoV-2 for all six VA healthcare centers.\u201d Does this mean the patients enrolled in this study are from one of six VA hospitals, or they are from all six hospitals?3. Authors wrote, \u201cthe CDC provides a list of chronic medical conditions (May 2021) that predispose individuals to severe illness from SARS-CoV-2 infection , but >754. In the Abstract, the authors wrote \u201cMultiple SARS-CoV-2 lineages were distributed in patients in New England early in the COVID-19 era, mostly related to viruses from New York with D614G mutation.\u201d Can the authors kindly clarify if it is New York State or New York City?"}
{"text": "Antihypertensive drugs have been of significant interest to the pharmaceutical industry due to increasing sales opportunities in a global market. The financial relationships between pharmaceutical companies and the Japanese Society of Hypertension (JSH) have a possible influence on clinical practices in Japan. This study examined the distribution of pharmaceutical payments made to the authors of the revised Guidelines for the Management of Hypertension (JSH2019) and the transparency of the Conflict of Interest disclosure that each author made.We retrospectively obtained publicly available data regarding payments made by Japanese pharmaceutical companies to all authors of the JSH2019 in 2016. We also collected data on individual financial disclosure of JSH2019 authors to investigate whether their self-reported financial relationship with companies were compliant to the financial disclosure policy of JSH2019.The total and mean payment values reported by pharmaceutical companies were $4,246,436 and $21,447, respectively. Of the 198 authors, 171 (86.4%) authors received at least 1 payment. Of 74 authors required to disclose their conflict of interest (COI) the authors, one-third failed to follow the COI policy covering the clinical guidelines.Major pharmaceutical companies selling antihypertensive drug products in the Japanese market had a significant financial connection with the JSH2019 authors. Financial relationships between pharmaceutical companies and authors or Japanese medical societies are raising significant concerns about the credibility of clinical guidelines and the potentially biases and undue influences that they may cause, especially with respect to adverse prescription patterns. However, the scope of antihypertensive treatment in the Japanese population has not been fully investigated, which raises concerns about possible unwarranted pharmaceutical industry influences.Antihypertensive drugs are attractive targets for the pharmaceutical industry due to their high income-generating potential. In April 2019, the Japanese Society of Hypertension (JSH) published a set of revised Guidelines for the Management of Hypertension (JSH2019).,3 Therefore, the general principal of hypertension management is to choose any or the most appropriate or available drug, unless the patient has a specific clinical reason otherwise, such as contraindication or pregnancy. Furthermore, observations suggest that reduction in cardiovascular risk is also independent of the drug choice, being due simply to the amount of blood pressure reduction.,5 In response to this, pharmaceutical companies manufacture a variety of antihypertensive drugs meaning there is a wide variety of quite similar drugs competing in the market. In such a competitive market, the marketing and promotional activities of pharmaceutical companies are almost certain to be tightly focused on those individuals who have a major influence on prescription policies and behavior. Considering the extensive recent clinical trial misconduct of Valsartan, an ARB manufactured by Novartis, involving JSH members and their still unchanged financial tie with pharmaceutical companies after the scandal, the authors of clinical practice guidelines (CPGs) should be completely transparent about any potential conflicts of interest (COIs), especially with respect to links with the pharmaceutical industry. We consequently investigated the extent and characteristics of financial COIs declared by the JSH2019 authors.Today, the first-line antihypertensive drugs used in practice comprise 4 main classes: angiotensin-converting enzyme (ACE) inhibitors, angiotensin II receptor blockers (ARBs), thiazide diuretics, and calcium channel blockers (CCBs). Both the ACC (AHA2017 guidelines) and JSH2019, mention that there are no significant differences in the effect and safety of antihypertensive drugs in each class in lowering blood pressure among 30% to 50% of patients.2 These payments are usually counted as incomes of the authors, not as research funding or other donations. We also collected relevant data, including names, affiliations, positions of the authors from their affiliations\u2019 and other websites. Japanese yen were converted to United States of America dollars using the 2016 average monthly exchange rate of 108.8 yen per 1 US dollar.The 78 pharmaceutical companies belonging to the Japanese Pharmaceutical Manufacturers Association (JPMA) disclose data of payments that they make to all Japanese healthcare professionals as required under the voluntary Transparency Guideline for the Relation between Corporate Activities and Medical Institutions, which governs all JPMA member companies. We obtained data on payments made by JPMA member companies for lecturing, writing, and consulting to all JSH authors in 2016 using methods as previously described.We evaluated the accuracy of the financial COIs reported by the authors, by comparing them with the payments disclosed by the pharmaceutical companies; the JSH2019 has a COI disclosure section requiring named authors provide mandatory details of any monies received, in excess of \u00a5500,000 ($4596), from any pharmaceutical company for lecturing or writing work. Payments for consulting were excluded in this analysis as they were not covered in the JSH2019 COI disclosure requirements. Institutional ethical committee approval was obtained from the Committee on the Medical Governance Research Institute, Minato-ku, Tokyo, Japan. Informed consent from the JSH2019 authors was not obtained as the payment data included in this study was collected from the publicly available data disclosed on the official homepage of each pharmaceutical company.3The JSH2019 had 198 authors: 146 (73.7%) were employees at universities or university hospitals and 92 (46.5%) were university professors. Payments totalled $4,246,436  in 2018.,10\u201315 This damages the credibility and trustworthiness of the JSH2019, especially as the update is advantageous for the pharmaceutical industry. Clearly, it is imperative that author COI disclosure policies need to be both clarified and rigorously enforced. Further, all authors need to comply and guideline publishers have to take responsibility to ensure that all requirements have been met in full and that all necessary details are published accurately.Notably, a third of JSH2019 authors clearly failed to comply with COI regulations, despite serious misconduct in Japan that led to the 2018 rigid enforcement of the Clinical Trials Act by Japan's Ministry of Health, Labour and Welfare. Comparably, the previous investigation regarding pharmaceutical payment received by Japanese CPG authors also documented that under-reported and imprecise FCOI were found in profound number of authors.,10\u201315 As a countermeasure, the recruitment of CPG authors should be revised. It is true that a balanced compilation of CPG authors requires healthcare professionals, namely physicians, with abundant clinical experience and knowledge about the latest evidence in any specific medical field. However, it is to be noted that Japanese physicians mainly receive payments from pharmaceutical companies by serving as lecturers and often leave their own hospitals and travel throughout the country. In this regard, it is questionable how familiar these physicians are with current frontline clinical practice.As explained above, financial ties between the CPG authors and pharmaceutical companies are prevalent and still ongoing issue surrounding clinical practice in Japan.Limitations in our study include potential payment underestimates due to lack of information regarding research funding, donations, travel fees, meals, and other gifts, while payments from the medical device industry could not be included. Further, our manual handling of large volume payments data may have produced some errors in estimation of individual payment values.5In conclusion, we demonstrated significant financial relationships between pharmaceutical industry and the authors of JSH2019 even after the unprecedented misconduct related to antihypertensive drugs. Given the long-standing ties between the pharmaceutical industry and Japanese medical societies, significant concerns exist about the ethical and potentially corrupt nature of these relationships, which could cause biased and potentially harmful prescription patterns, as well as increased health care costs that could threaten the sustainability of Japan's globally-acclaimed universal health coverage and world-leading health care system.Conceptualization: Akihiko Ozaki, Tetsuya Tanimoto.Data curation: Hiroaki Saito.Formal analysis: Yuki Senoo, Hiroaki Saito, Toyoaki Sawano.Investigation: Hiroaki Saito, Akihiko Ozaki, Toyoaki Sawano.Supervision: Tetsuya Tanimoto.Visualization: Yousuke Suzuki, Tetsuya Tanimoto.Writing \u2013 original draft: Yuki Senoo, Akihiko Ozaki.Writing \u2013 review & editing: Yuki Senoo, Hiroaki Saito, Akihiko Ozaki, Toyoaki Sawano, Yuki Shimada, Kana Yamamoto, Yousuke Suzuki, Tetsuya Tanimoto."}
{"text": "Tu M, Jia HX and Liu HP performed the experiments. Wang XJ and Wang Y analyzed the data. Wang YB and Jiang N contributed analysis tools. Lu CY provided critical inputs on design, analysis, and interpretation of the study. All the authors had access to the data. All authors read and approved the final manuscript as submitted."}
{"text": "They also apologize to the readership for any inconvenience caused.The authors were able to re-examine their original data files, and realize how the errors were made during the assembly of this figure. The revised version of"}