Long-term effects and costs of pelvic floor muscle training for prolapse: trial follow-up record-linkage study
Linda Fenocchi*, Catherine Best, Helen Mason, Andrew Elders, Suzanne Hagen, Margaret Maxwell
NMAHP
Introduction and hypothesis: Pelvic organ prolapse affects around 40% of women aged over 50 years. A multicentre parallel group randomised trial (the Pelvic Organ Prolapse PhysiotherapY (POPPY) trial) demonstrated that pelvic floor muscle training (PFMT) was effective in reducing prolapse symptoms compared with no treatment. However, insight into the long-term impact of PFMT on health outcomes and health-service utilisation is scarce. Methods: This study utilised linkage of Scottish administrative health records to follow-up POPPY trial participants resident in Scotland over 11 years. Mixed effects logistic regression determined the likelihood of receiving further prolapse treatment for those in the PFMT and control groups. Analyses were adjusted for age group, prolapse stage, baseline symptom severity and attitude towards surgery. A cost assessment estimated longitudinal costs to the UK National Health Service (in Scotland) of accessing further prolapse treatment for each trial group. Results: Two hundred and ninety-three women, aged 25 to 79 years, were followed up. One hundred and forty-one women (48.1%) had received further prolapse treatment: 65 (of 149; 43.6%) in the PFMT group compared with 76 (of 144; 52.8%) in the control group. PFMT was associated with a reduction in the odds of any prolapse treatment during follow-up (AOR 0.61; 95% CI 0.37 to 0.99). Total cost of secondary care was £154,544 (GBP) in the PFMT group and £172,549 (GBP) in the control group. Conclusions: Although PFMT did not lead to significant differences in total costs for further prolapse treatment over a post-intervention period of more than 10 years, it reduced the overall long-term risk of requiring hospital-based treatment for pelvic floor disorders.
International Urogynecology Journal
record linkage
longitudinal cost analysis
pelvic floor muscle training
randomised controlled trial
long-term follow-up
Economics, Econometrics and Finance(all)
Health Professions(all)
Fenocchi, L. et al (2022) Long‑term effects and costs of pelvic floor muscle training for prolapse: trial follow‑up record‑linkage study
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Dive into the research topics of 'Long-term effects and costs of pelvic floor muscle training for prolapse: trial follow-up record-linkage study'. Together they form a unique fingerprint.
Record Linkage Business & Economics 100%
Pelvic Floor Medicine & Life Sciences 71%
Prolapse Medicine & Life Sciences 68%
Muscles Medicine & Life Sciences 36%
Pelvic Organ Prolapse Medicine & Life Sciences 32%
Costs Business & Economics 22%
Scotland Medicine & Life Sciences 19%
Fenocchi, L., Best, C., Mason, H., Elders, A., Hagen, S., & Maxwell, M. (2022). Long-term effects and costs of pelvic floor muscle training for prolapse: trial follow-up record-linkage study. International Urogynecology Journal. https://doi.org/10.1007/s00192-022-05272-9
Fenocchi, Linda ; Best, Catherine ; Mason, Helen et al. / Long-term effects and costs of pelvic floor muscle training for prolapse: trial follow-up record-linkage study. In: International Urogynecology Journal. 2022.
@article{863796233f894e1fbd0bec317388d8e0,
title = "Long-term effects and costs of pelvic floor muscle training for prolapse: trial follow-up record-linkage study",
abstract = "Introduction and hypothesis: Pelvic organ prolapse affects around 40% of women aged over 50 years. A multicentre parallel group randomised trial (the Pelvic Organ Prolapse PhysiotherapY (POPPY) trial) demonstrated that pelvic floor muscle training (PFMT) was effective in reducing prolapse symptoms compared with no treatment. However, insight into the long-term impact of PFMT on health outcomes and health-service utilisation is scarce. Methods: This study utilised linkage of Scottish administrative health records to follow-up POPPY trial participants resident in Scotland over 11 years. Mixed effects logistic regression determined the likelihood of receiving further prolapse treatment for those in the PFMT and control groups. Analyses were adjusted for age group, prolapse stage, baseline symptom severity and attitude towards surgery. A cost assessment estimated longitudinal costs to the UK National Health Service (in Scotland) of accessing further prolapse treatment for each trial group. Results: Two hundred and ninety-three women, aged 25 to 79 years, were followed up. One hundred and forty-one women (48.1%) had received further prolapse treatment: 65 (of 149; 43.6%) in the PFMT group compared with 76 (of 144; 52.8%) in the control group. PFMT was associated with a reduction in the odds of any prolapse treatment during follow-up (AOR 0.61; 95% CI 0.37 to 0.99). Total cost of secondary care was £154,544 (GBP) in the PFMT group and £172,549 (GBP) in the control group. Conclusions: Although PFMT did not lead to significant differences in total costs for further prolapse treatment over a post-intervention period of more than 10 years, it reduced the overall long-term risk of requiring hospital-based treatment for pelvic floor disorders.",
keywords = "pelvic organ prolapse, record linkage, longitudinal cost analysis, pelvic floor muscle training, randomised controlled trial, long-term follow-up",
author = "Linda Fenocchi and Catherine Best and Helen Mason and Andrew Elders and Suzanne Hagen and Margaret Maxwell",
journal = "International Urogynecology Journal",
publisher = "Springer London",
Fenocchi, L, Best, C, Mason, H, Elders, A, Hagen, S & Maxwell, M 2022, 'Long-term effects and costs of pelvic floor muscle training for prolapse: trial follow-up record-linkage study', International Urogynecology Journal. https://doi.org/10.1007/s00192-022-05272-9
Long-term effects and costs of pelvic floor muscle training for prolapse: trial follow-up record-linkage study. / Fenocchi, Linda; Best, Catherine; Mason, Helen et al.
In: International Urogynecology Journal, 28.06.2022.
T1 - Long-term effects and costs of pelvic floor muscle training for prolapse: trial follow-up record-linkage study
AU - Fenocchi, Linda
AU - Best, Catherine
AU - Mason, Helen
AU - Elders, Andrew
AU - Hagen, Suzanne
AU - Maxwell, Margaret
N2 - Introduction and hypothesis: Pelvic organ prolapse affects around 40% of women aged over 50 years. A multicentre parallel group randomised trial (the Pelvic Organ Prolapse PhysiotherapY (POPPY) trial) demonstrated that pelvic floor muscle training (PFMT) was effective in reducing prolapse symptoms compared with no treatment. However, insight into the long-term impact of PFMT on health outcomes and health-service utilisation is scarce. Methods: This study utilised linkage of Scottish administrative health records to follow-up POPPY trial participants resident in Scotland over 11 years. Mixed effects logistic regression determined the likelihood of receiving further prolapse treatment for those in the PFMT and control groups. Analyses were adjusted for age group, prolapse stage, baseline symptom severity and attitude towards surgery. A cost assessment estimated longitudinal costs to the UK National Health Service (in Scotland) of accessing further prolapse treatment for each trial group. Results: Two hundred and ninety-three women, aged 25 to 79 years, were followed up. One hundred and forty-one women (48.1%) had received further prolapse treatment: 65 (of 149; 43.6%) in the PFMT group compared with 76 (of 144; 52.8%) in the control group. PFMT was associated with a reduction in the odds of any prolapse treatment during follow-up (AOR 0.61; 95% CI 0.37 to 0.99). Total cost of secondary care was £154,544 (GBP) in the PFMT group and £172,549 (GBP) in the control group. Conclusions: Although PFMT did not lead to significant differences in total costs for further prolapse treatment over a post-intervention period of more than 10 years, it reduced the overall long-term risk of requiring hospital-based treatment for pelvic floor disorders.
AB - Introduction and hypothesis: Pelvic organ prolapse affects around 40% of women aged over 50 years. A multicentre parallel group randomised trial (the Pelvic Organ Prolapse PhysiotherapY (POPPY) trial) demonstrated that pelvic floor muscle training (PFMT) was effective in reducing prolapse symptoms compared with no treatment. However, insight into the long-term impact of PFMT on health outcomes and health-service utilisation is scarce. Methods: This study utilised linkage of Scottish administrative health records to follow-up POPPY trial participants resident in Scotland over 11 years. Mixed effects logistic regression determined the likelihood of receiving further prolapse treatment for those in the PFMT and control groups. Analyses were adjusted for age group, prolapse stage, baseline symptom severity and attitude towards surgery. A cost assessment estimated longitudinal costs to the UK National Health Service (in Scotland) of accessing further prolapse treatment for each trial group. Results: Two hundred and ninety-three women, aged 25 to 79 years, were followed up. One hundred and forty-one women (48.1%) had received further prolapse treatment: 65 (of 149; 43.6%) in the PFMT group compared with 76 (of 144; 52.8%) in the control group. PFMT was associated with a reduction in the odds of any prolapse treatment during follow-up (AOR 0.61; 95% CI 0.37 to 0.99). Total cost of secondary care was £154,544 (GBP) in the PFMT group and £172,549 (GBP) in the control group. Conclusions: Although PFMT did not lead to significant differences in total costs for further prolapse treatment over a post-intervention period of more than 10 years, it reduced the overall long-term risk of requiring hospital-based treatment for pelvic floor disorders.
KW - pelvic organ prolapse
KW - record linkage
KW - longitudinal cost analysis
KW - pelvic floor muscle training
KW - randomised controlled trial
KW - long-term follow-up
JO - International Urogynecology Journal
JF - International Urogynecology Journal
Fenocchi L, Best C, Mason H, Elders A, Hagen S, Maxwell M. Long-term effects and costs of pelvic floor muscle training for prolapse: trial follow-up record-linkage study. International Urogynecology Journal. 2022 Jun 28. doi: 10.1007/s00192-022-05272-9