Ligand-gated
Glutamate, ionotropic
GYKI 53655
GYKI 53655 - LY 300168
MF C19H20N4O3
Soluble in DMSO and Ethanol
Selective AMPA receptor antagonist; a more useful tool than NBQX for the study of AMPA receptor-mediated processes in vivo
BA Chizh et al. A comparison of intravenous NBQX and GYKI 53655 as AMPA antagonists in the rat spinal cord. Br. J. Pharmacol. 1994, 112(3), 843-6.
AD Kovács and G Szabó. GYKI 53655, a 2,3-benzodiazepine, non-competitively protects cultured neurones against AMPA toxicity. Eur. J. Pharmacol. 1997, 331(1), 93-96.
Szabados et al. Comparison of anticonvulsive and acute neuroprotective activity of three 2,3-benzodiazepine compounds, GYKI 52466, GYKI 53405 and GYKI 53655. Brain. Res. Bull. 2001, 55 387.
CNS Pain & Inflammation AMPA Unclassified
AMPA antagonist
5-(4-Amino-phenyl)-8-methyl-8,9-dihydro-1,3-dioxa-6,7-diaza-cyclohepta[f]indene-7-carboxylic acid methylamide
2 mg €85.00 In Stock 0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50
5 mg €125.00 In Stock 0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50
2 x 5 mg €180.00 In Stock 0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25
2 x 25 mg €640.00 In Stock 0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25
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1830 VU 0364439 Positive allosteric modulator (PAM) of mGluR4 €115.00
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2640 TFB-TBOA Very potent blocker of human excitatory amino acid transporters (EAAT1-2) €145.00
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