We recently showed that interleukin-1 (IL-1) is secreted by the placenta of a species of squamate reptile, the three-toed skink, Chalcides chalcides. In this study, we used immunohistochemical techniques to investigate the expression of IL-1 (in the two isoforms, IL-1α and IL-1β) and its specific membrane receptor IL-1 RtI in uterine oviduct during the peri-implantation period. We found that both IL-1 and its receptor were expressed in uterine tissues before and after ovulation (in the pre-ovulatory stage, even before the yolk had formed in the ovary). However, while IL-1α was mostly localized in the uterine mesenchyme tissue, IL-1β and IL-1RtI were present in the uterine epithelium. Our data provide a further comparison between the reproduction of mammals and squamate reptiles. © 2003 Romagnoli et al; licensee BioMed Central Ltd.
Romagnoli, R., Cateni, C., Guarino, F.M., Bigliardi, E., Ricci, L. (2003). Potential role of interleukin-1 at the peri-ovulation stage in a species of placental viviparous reptile, the three-toed skink, Chalcides chalcides (Squamata: Scincidae). REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY, 1 [10.1186/1477-7827-1-60].
Potential role of interleukin-1 at the peri-ovulation stage in a species of placental viviparous reptile, the three-toed skink, Chalcides chalcides (Squamata: Scincidae)
Romagnoli, Roberta;Cateni, C.;Guarino, F. M.;Bigliardi, Elisa;Ricci, Luana
REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY
interleukin-1 at the peri-ovulation stage.pdf
Tipologia: Post-print