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Device for carrying out patient drug test
A61H39 - Devices for locating or stimulating specific reflex points of the body for physical therapy, e.g. acupuncture (locating by bioelectric signal detection A61B0005040000; locating by using electric currents or magnetic fields A61B0005050000)
A61B5/05 - Measuring for diagnosis by means of electric currents or magnetic fields (A61B0005020000, A61B0005040000, A61B0005110000 take precedence);;
FIELD: medical engineering.
SUBSTANCE: device has test unit having unit for treating the object under study, unit for programmed recording and processing data having amplifier and analog-to-digital converter connected to computer device having display unit. The test unit and unit for treating the object under study are manufactured as at least two radiation sources operating in red radiation bandwidth, the sources being connected to power supply source, and at least two photodetectors, each making an optoelectronic oxyhemometric transducer with corresponding radiation source. Each transducer is connected to multi-channel analog-to-digital converter via corresponding amplifier. The unit for programmed recording and processing data norms relationships of blood saturation with oxygen on amplitude recorded in time for each optoelectronic transducer to determine their phase difference.
EFFECT: enhanced effectiveness of tests.
5 cl, 1 dwg
The invention relates to medicine, namely to medical technology and can be used for individual selection of a single dose of a drug without drinking when performing acupuncture, electroacupuncture, thermal and drug therapy.
You know the testing of drugs by R. Voll [1], which consists in selecting appropriate to the patient's drug without its introduction into the body on the basis of electropunctural diagnostics carried out by measuring the current flowing in the measuring circuit electrodes-acupuncture point (AT), at constant pressure of the electrode on the skin, by using a device for measuring electrical characteristics AT for some time. Patient enough to touch the medicine hand on the basis of the phenomenon of long-range is determined by the effectiveness of its action on the patient not only in the molecular contact, but at a distance. The impact of the drug is measured indirectly by the reaction of the body, and the indicator is acupuncture system that allows you to differentiate and assess the direction of reaction of the organism. This compares the value of the normalized current value measured in the presence and absence of drug. Deviations from the normalized values are the basis of lasalette about improvement or deterioration in the functioning of an organ or system of the body.
It is also known a device for non-invasive rapid diagnosis [2], containing the power source, the measuring unit with the display device and the electrodes from the test micronesians path.
The device allows the change of electric conductivity to assess the reaction of the organism to the influence of various substances. A disadvantage of the known devices is the significant duration of the diagnostic process, which is associated with the need to determine the optimal acupuncture points on the patient, and the low diagnostic accuracy due to the influence of external electromagnetic fields on acupuncture points.
The closest in technical essence of the present invention is a device for carrying out drug testing [3], contains a unit test that includes multiple microresearch contours and elements of their switching, software registration unit for registering and processing information, comprising measuring the conductivity AT the amplifier, analog-to-digital Converter (ADC) and the computing device from the renderer. This separate unit is executed unit impact on the research object, containing the constant current source and the electrodes for contact with the patient's body. In the known device is not actually used information is, related to the dynamics of the measurement characteristics of the study at a particular selected testing effect, which reduces the efficiency of testing and the accuracy of selection drug. In addition, the overall significant disadvantage of all these known devices is that they all conduct testing of the drug product to the patient by the method of measuring the electrical conductivity in AT. Also patients can have multiple and related primary diagnosis of disorders that affect the conductive properties of the tissue studied AT and not allowed to have reference information about the parameters of "normal tissue".
The present invention aims at eliminating the above drawbacks. Technical result achieved in its implementation, is to increase the effectiveness of drug testing due to selection of drug from the device, not affected by external electromagnetic fields. While tracking the dynamics of research and software processing of the obtained data allow us to obtain conclusions about effective dose of a particular drug, adequate to the current state of the patient, to improve the accuracy of measurement due to the removal of the fatigue of operator error is a, conducting research, and automation research.
The essence of the invention lies in the fact that the device for carrying out drug testing of the patient, consisting of unit testing and software recording unit and information processing, including the amplifier and analog-to-digital Converter, connected to a computing device with a display facility, the testing unit is made in the form of block impact on the research object, containing at least two sources of radiation in the red range of the radiation that is connected to the current source, and at least two photodetectors, each of which is with an appropriate radiation source optoelectronic sensor, each of which, in turn, is connected through an appropriate amplifier to the multi-channel analog-to-digital Converter, and software registration unit for registering and processing information is configured to normalize the amplitude of the recorded time of the study the dependence of the parameter of the blood oxygen saturation for each optoelectronica sensor and calculating the integral of the difference of the parameter dependencies of the blood oxygen saturation to determine the phase difference. Each optoelectronic sensor may be provided with a fastening element, for example to what IPSAS and connector, to connect to the amplifier.
Unit testing with site effects on the research object preferably is a five optoelectronic sensors made with the possibility of installation on the fingers (or other body parts of the patient).
Software registration unit and information processing can conduct self-test mode by normalizing the amplitude dependence of the parameter of the blood oxygen saturation for each oxygenations sensor relative to a predetermined test value.
Working wavelength optoelectronic sensor may be 660 or 670 or 680 nm.
The invention is illustrated by the drawing, which shows a block diagram of a device for carrying out drug testing of the patient.
The device for carrying out drug testing of a patient, comprises a testing unit with unit effects on the object of study of several optoelectronic sensors 1, each of which consists of a radiation source in the red range light (led)connected to the current source, and a sensor (sensor saturation of arterial blood with oxygen in the present invention measures the absorption of the hemoglobin of the red light). Sensors set or fixed by fastening elements, which for example clips, on the studied biological surface. As the surface is preferred to conduct research, often choose the fingers or it may be the lobe of the ear or any other part of the body of the patient. The most preferred option for installation of the sensors is fixing of the five sensors on the fingers of one hand. Normal operating values for red LEDs, used in oxigenate, are in the range of 645 and 680 nm, most often 660, 670 or 680 nm, selected for maximum sensitivity measurements.
Each optoelectronic sensor 1 is connected via a respective amplifier 2 to the multi-channel analog-to-digital Converter 3, which constitutes together with the computing device 4, provided with a display device (display) 5, software registration unit for registering and processing information, which is made with the possibility of self-test mode by normalizing the amplitude dependence of the absorption by the hemoglobin in the blood red light from time to time for a parameter of the blood oxygen saturation of each optoelectronic oxygenations sensor relative to a predetermined test value, as well as regulation on the amplitude of the recorded time of the study the dependence of the absorption by the hemoglobin of the red light and, thus, the parameter is the oxygen saturation of blood for each optoelectronic sensor and calculating the integral of the difference of normalized parameter dependencies of the blood oxygen saturation to determine the phase difference.
The operation of the device is as follows.
The sensor 1 is fixed on the surface, such as the fingers, while the nail phalanx of the finger is fixed in the sensor between its elements so that the nail is facing the emitter. After using the program block settings for conducting the self-test mode of the device. When this message appears on the phase deviation of the readings of each detector from a given value determined by a specific type of LEDs. For example, the phase deviation can be -38, -28, -20, -10 milliseconds. Next, conduct testing of the patient in the absence of any medical intervention. The light from each source of radiation is propagated through the corresponding test environment, in part, it absorbed and accepted by the photodetector generating an electrical current indicating the intensity of the incident light radiation. This signal is applied to the corresponding amplifier and through a multichannel ADC digitized analyzed by the computing device to determine information related to the medium through which were transmitted light energy, and to determine its characteristics. The recorded time-dependence of pogloshena the hemoglobin of the blood red light and the parameter of the blood oxygen saturation for each sensor is normalized in amplitude, after that is determined by the integral of the difference of normalized parameter dependencies. The minimum value of the normalized amplitude time defined for the readings of each sensor, characterizes the deviation of the phase of the sensor in this measurement. Repeated testing of a patient after drug exposure, which may consist not only in the use of the medicinal product placed on the skin surface, but also to represent the energy electromagnetic radiation, heat or sound waves in therapeutic range. The resulting study deviations of the phases will have different values for the same sensors. In this case, if the phase difference with repeated measurement decreases, the reaction to test the impact is positive. Otherwise (when increasing the phase difference) is a negative reaction to the drug.
When conducting drug testing doctor after selection of the drug or exposure enters the information into the computing device. On the incorporated program recommendations for treatment.
1. Lupachev D., Electroacupuncture diagnosis, homeopathy and the phenomenon of long-range action. M, Iris, 1990.
2. SU 160696, 1990.
3. SU 1787016, 1993.
1. The device for carrying out drug testing patient containing unit testing with the unit effects on the object of study and the program block reception and processing of information, including the amplifier and analog-to-digital Converter, connected to the computing device from the renderer, wherein the testing unit with unit exposure to the research object contains at least two sources of radiation in the red range of the radiation that is connected to the current source, and at least two photodetectors, each of which is with an appropriate radiation source optoelectronic sensor, each of which, in turn, connected through an appropriate amplifier to the multi-channel analog-to-digital Converter, the software unit of recording and processing information is configured to normalize the amplitude of the recorded time of the study the dependence of the parameter of the blood oxygen saturation for each optoelectronic sensor, and calculating the integral of the difference of normalized parameter dependencies of the blood oxygen saturation to determine the phase difference.
2. The device according to claim 1, characterized in that the optoelectronic sensor is equipped with a fastening element, for example CL is Psoy, and a connector for connection to the amplifier.
3. Device according to claims 1 and 2, characterized in that the testing unit with unit exposure to the object of research is made in the form of five optoelectronic sensors made with the possibility of installation on the fingers.
4. The device according to claim 1, characterized in that the program block reception and processing of information is performed with the mode of learning through regulation of the amplitude dependence of the parameter of the blood oxygen saturation of each optoelectronic sensor relative to a predetermined test value of the parameter.
5. Device according to claims 1 to 4, characterized in that the working wavelength optoelectronic sensor 660, or 670 or 680 nm.
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