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600 Pages | 48 black and white line drawings
This book is available as part of Oxford Medicine Online
Nutrition and the Cancer Patient
Edited by Egidio Del Fabbro, Eduardo Bruera, Wendy Demark-Wahnefried, Tim Bowling, Jane B. Hopkinson, and Vickie E. Baracos
Will enable physicians, nurses and also dieticians to better discuss the complex issues of nutrition with cancer patients and their families
Provides both background information and practical, clinical advice
Includes information that relates to patients who are continuing to receive disease-specific therapy, the cancer survivor, as well as patients with advanced or recurrent cancer receiving palliative care
Nutrition, appetite, and involuntary weight loss are issues that affect a large number of cancer patients and cancer survivors. Aspects such as symptom management, behavioural modification, exercise and medication are all important aspects of cancer care, but nutritional issues at the end of life can be accompanied by contentious ethical factors as well as religious and cultural influences that need to be addressed by health professionals. This book enables physicians, nurses and also dieticians to better discuss these complex issues with patients and their families.
This comprehensive reference book provides both background information and practical, clinical advice for managing the cancer patient at all stages of their disease trajectory. It includes information that relates to patients who are continuing to receive disease-specific therapy, the cancer survivor, as well as patients with advanced or recurrent cancer receiving palliative care.
Basic principles such as epidemiology and physiology set the scene, leading into the cachexia/anorexia syndrome, treatment options, nutritional counselling, enteral and parenteral nutrition, complementary/alternative therapies, exercise, clinical outcomes measures in each of the clinical groups, and focus on special populations and their specific needs. Multidimensional, interdisciplinary clinical evaluation and treatment is emphasised, and ethical, religious, and cultural factors are also addressed.
Multidisciplinary in nature, this book draws on the experience of the editors' work across the fields of oncology, palliative care, surgery, primary care, nursing, dietetics and nutritional science. It will prove invaluable to all general practitioners, internists, medical oncologists and surgeons, nurses, palliative care specialists and related professionals involved in the care of the cancer patient.
1 - Basic principles
1. Definitions and epidemiology, Vickie E. Baracos
2. Metabolism and physiology, Vickie E. Baracos and Henrique A. Parsons
3. The assessment of nutritional status, Vickie E. Baracos, CMM Prado, S Antoun, and I Gioulbasanis
2 - The cachexia/anorexia syndrome
4. The epidemiology of body weight and body weight loss and its relation to cancer, Egidio Del Fabbro and Vickie E. Baracos
5. The mechanisms of primary cachexia, Vickie E. Baracos and Henrique A. Parsons
3 - The treatment of primary cachexia
6. Challenges and opportunities in conducting clinical research in cancer cachexia, Henrique A. Parsons and Eduardo Bruera
7. Appetite stimulants, Florian Strasser
8. Anabolic hormones, Jose Garcia
9. Immune modulators, Egidio del Fabbro
10. Autonomic system modulators, Nada Fadul
11. Multimodality therapy, Eduardo Bruera and Egidio del Fabbro
4 - The treatment of secondary cachexia
12. Classification of cancer cachexia and secondary nutrition impact symptoms, Florian Strasser
13. Oral complications, Carla Ida Ripamonti, Nicla La Verde, Gabriella Farina, and Marina Chiara Garassino
14. Nausea and vomiting in advanced cancer, Mellar P. Davis
15. Early satiety, Mellar P. Davis
16. Disordered bowel function, David Blum
17. Depression and fatigue, Elizabeth Kvale, Casey Balentine Azuero, and Eric Walker
5 - Nutritional counselling
18. Counselling by a dietitian, Laura Elliot and Barbara Parry
19. The multi-disciplinary approach to nutritional problems in patients with cancer, Colette Hawkins, Inga Andrew, Tessa Aston, Trevelyan Beyer, Jacqueline Cairns, Bob Hansford, Jane Hopkinson, Reverend Caroline Worsfold
6 - Artificial nutritional support
20. Nutritional support: an overview, Tim Bowling
21. Oral and enteral nutrition, Jeremy Woodward
22. Nutrition in advanced malignancy: parenteral nutrition, palliative surgery and gastrointestinal stents, Pradeep F. Thomas and Dileep N Lobo
7 - Ethics, culture and spirituality
23. Ethics and medically assisted nutrition and hydration in cancer, Paulina Taboada, Alejandra Palma, and Beatriz Shand
24. Cultural and religious factors, Sarah Toule
8 - Nutrition and Complementary and Alternative Medicine (CAM) in cancer
25. Nutrition and Complementary and Alternative Medicine (CAM) in cancer care, Eran Ben-Arye, Dena Norton, Moshe Frenkel, and Nicola Hembry
9 - Exercise
26. Exercise therapy for persons diagnosed with cancer, Lee W. Jones
10 - Clinical groups
27. The cancer survivor, Wendy Demark-Wahnefried
28. Nutritional management of patients receiving primary cancer therapy, R.D. Johnston, R.A. Barrett, and T.E. Bowling
29. Nutritional management of patients with recurrent, advanced or metastatic cancer, Shalini Dalal
30. Patients at the end of life, Egidio del Fabbro
11 - Special opulations
31. Paediatric patients, Sian Kirkham and Martin Hewitt
32. Nutritional care of older people with cancer, Jane Hopkinson and Christopher Bailey
33. Nutrition and comorbidities in patients with cancer, Marvin Omar Delgado Guay
34. Patients in the developing world, Richard Harding and Liz Gwyther
35. The experience of involuntary weight loss and altered body image in patients with cancer anorexia-cachexia syndrome (CACS): Patient and family perspectives, Susan E. McClement
After medical school at the University of the Witwatersrand, South Africa, Egidio Del Fabbro completed his residency in Internal Medicine at Barnes Jewish Hospital, St. Louis in 1998. Following 5 years of internal medicine practice he completed a palliative care fellowship at MD Anderson Cancer Center. In his current position as Assistant Professor in the Palliative Care and Rehabilitation department and co-director of the Cachexia clinic at MD Anderson the goal is to increase the awareness of conditions affecting the quality of life of cancer patients such as poor appetite, fatigue and testosterone deficiency. He is the Principal Investigator of two prospective clinical intervention trials including melatonin for appetite in patients with cancer and multimodality therapy for cachexia. He is funded by the American Cancer Society to explore the effect of testosterone replacement in male patients with advanced cancer and serves on scientific committees at national and international conferences. Eduardo Bruera, MD, is Chair of the Department of Palliative Care and Rehabilitation Medicine and holds the F. T. McGraw Chair in the Treatment of Cancer at The University of Texas M. D. Anderson Cancer Center in Houston, Texas. Dr. Bruera is Vice President of the International Association of Hospice and Palliative Care. He is a member of the editorial board of several pain, palliative care, and cancer journals. He has received a number of national and international awards for his clinical and research commitment to the management of pain and other symptoms. Dr. Bruera's research has focused on clinical trials of pain and other symptoms, and health services research regarding supportive and palliative care. Dr Demark-Wahnefried is a nutrition scientist whose research spans basic science studies focused on determining the role of food-related components on cancer progression, to clinical research that involves nutrition-related concerns of cancer patients, as well as determining effective lifestyle interventions that improve the overall health of cancer survivors and their families. Her laboratory has conducted some of the largest studies exploring metabolic and body composition changes in response to cancer treatment. In 2003 she was named Komen Professor of Survivorship for her work in energy balance and breast cancer. An area of research in which she has particular expertise is in the delivery of home-based lifestyle interventions, where she has led and continues to lead several NIH-funded trials to improve the diet and exercise behaviors of cancer survivors. She also has actively contributed to national guidelines for cancer survivors (e.g., Institute of Medicine and the American Cancer Society). Dr Bowling qualified at St Bartholomew's Medical School, University of London, in 1986. After a variety of junior posts, he was appointed as a research fellow with Professor David Silk at the Central Middlesex Hospital. For his MD thesis he looked at the in vivo human colonic responses to intragastric and intraduodenal enteral feeding. For this work he was awarded the Sir David Cuthbertson Research Medal. In 1996 he was appointed as a Consultant in Gastroenterology at the University Hospital of North Staffordshire. He started a multidisciplinary nutrition support team, which introduced various innovative practices, that have since been copied by many other UK hospital teams. In 2003 he took up his current post in Nottingham as a Gastroenterologist and running a regional intestinal failure unit. He is clinical lead for nutrition at the Nottingham University Hospitals and leads the nutrition support team. Jane Hopkinson is a Macmillan Post Doctoral Research Fellow, who specialises in the study of supportive and palliative care for people with cancer. She is a nurse who worked clinically in the fields of cancer and palliative care prior to becoming a full-time academic seven years ago. Since 2002, her research has been investigating the problems of living with weight loss and eating difficulties for people with advanced cancer and their families. The purpose of this programme of research is to develop innovative ways of supporting people living with cancer cachexia syndrome. She regularly speaks about her work at both national and international meetings, in addition to publishing on the subject. Dr Vickie E. Baracos' research program on muscle and protein metabolism spans two decades and is related to different physiologic and pathologic states where muscle protein growth or wasting occur, including cancer, chemotherapy, sepsis, injury, diabetes, diet, environmental stress and lactation.
Inga Andrew, Senior Clinical Pharmacist
S. Antoun
Tessa Aston, Macmillan Specialist Dietitian
Christopher Bailey, Senior Research Fellow, School of Health Sciences, University of Southampton, UK
Casey Balentine Azuero, University of Alabama at Birmingham, Center for Palliative Care, and University of Alabama at Birmingham, Division of Preventive Medicine, Birmingham, USA
Vickie E. Baracos, Professor & Alberta Cancer Foundation Chair in Palliative Medicine, University of Alberta, Edmonton, Canada
RA Barrett, Principal Haematology/Oncology Dietitian, Guy's and St Thomas' NHS Foundation Trust, London, UK
Eran Ben-Arye, Integrative Oncology Program, The Oncology Service, Lin Medical Center, Clalit Health Services, Haifa and Western Galilee District, Israel; The Complementary and Traditional Medicine Unit, Department of Family Medicine, The Bruce Rappaport Faculty of Medicine, The Technion, Israel Institute of Technology, Haifa, Israel
Trevelyan Beyer, Physiotherapist
Eduardo Bruera, Department of Palliative Care and Rehabilitation Medicine, The University of Texas M. D. Anderson Cancer Center, USA
T E Bowling, Consultant in Gastroenterology and Clinical Nutrition, Nottingham University Hospitals, Nottingham, UK
Jacqueline Cairn, Occupational Therapist
Marina Chiara Garassino, Oncology Department, Fatebenefratelli and Ophthalmic Hospital, Milan, Italy
Shalini Dalal
Mellar P. Davis, The Harry R. Horvitz Center for Palliative Medicine, Taussig Cancer Center, The Cleveland Clinic, USA
Marvin Omar Delgado Guay, The University of Texas Health Science Center at Houston
Department of Internal Medicine. Division of Geriatrics and Palliative Medicine. Lyndon B. Johnson General Hospital, Houston, USA
Laura Elliott, Mary Greeley Medical Center, Iowa, USA
Egidio del Fabbro, Assistant Professor of Palliative Care and Rehabilitation, The University of Texas M. D. Anderson Cancer Center, Houston, USA
Nada Fadul
Gabriella Farina, Oncology Department, Fatebenefratelli and Ophthalmic Hospital, Milan, Italy
Moshe Frenkel, Integrative Medicine Program, The University of Texas M. D. Anderson Cancer Center, Houston, USA
I Gioulbasanis
Liz Gwyther, Department of Family Medicine, University of Cape Town; Executive Director, Hospice Palliative Care Association of South Africa
Richard Harding, Senior Lecturer, King's College London, Department of Palliative Care, Policy & Rehabilitation, London, UK
Bob Hansford, Volunteer, St Benedicts Hospice, Sunderland, UK
Colette Hawkins, Macmillan Consultant in Palliative Medicine, University Hospital of North Durham, County Durham and Darlington NHS Foundation Trust, UK
Nicola Hembry
Martin Hewitt, Consultant in Paediatric Medicine & Paediatric Oncology & Child Health, Department of Child Health, Queens Medical Centre Campus, Nottingham University Hospital, UK
Jane Hopkinson, Macmillan Post Doctoral Research Fellow, School of Health Sciences, University of Southampton, UK
RD Johnston, Clinical Research Fellow, Wolfson Digestive Diseases Centre, University Hospital Nottingham, UK
Lee W. Jones, Duke University Medical Center, Durham, North Carolina, USA,
Wendy Demark-Wahnefried, University of Texas - M. D. Anderson Cancer Center, Houston, USA
Sian Kirkham, Consultant in Paediatric Gastroenterology, Hepatology & Nutrition
Elizabeth Kvale, Birmingham Veterans Administration Medical Center, and University of Alabama at Birmingham, Center for Palliative Care, Birmingham, USA
Nicla La Verde, Oncology Department, Fatebenefratelli and Ophthalmic Hospital, Milan, Italy
Dileep N Lobo, Associate Professor & Reader, Division of Gastrointestinal Surgery, Nottingham Digestive Diseases Centre Biomedical Research Unit, Nottingham University Hospitals, Queen's Medical Centre, Nottingham, UK
Susan E. McClement, Associate Professor, Faculty of Nursing, University of Manitoba Research Associate, Manitoba Palliative Care Research Unit, Winnipeg, Manitoba, Canada
Dena Norton, Integrative Medicine Program, The University of Texas M. D. Anderson Cancer Center, Houston, USA
Alejandra Palma, Instructor, Program of Palliative Medicine, Medical School, Pontificia Universidad Católica de Chile
Barbara Parry, Senior Research Dietitian, Winchester and Andover Breast Unit, Royal Hampshire County Hospital, Winchester, UK.
Henrique A. Parsons, Department of Palliative Care and Rehabilitation Medicine, The University of Texas M. D. Anderson Cancer Center, Houston, USA
CMM Prado
Beatriz Shand, Instructor, Center for Bioethics and Department of Neurology, Pontificia Universidad Católica de Chile
Florian Strasser
Carla Ida Ripamonti, Palliative Care Unit, IRCCS Foundation, National Cancer Institute of Milan, Italy
Paulina Taboada, Associate Professor, Pontificia Universidad Católica de Chile, Director of the Center for Bioethics
Pradeep F. Thomas, Specialist Registrar in Surgery, Nottingham University Hospitals, Queen's Medical Centre, Nottingham, UK
Sarah Toule, Cancer & Diet Information Project Lead, Cancer Equality, London, UK
Wendy Demark-Wahnefried, Professor of Behavioral Science, University of Texas - M. D. Anderson Cancer Center, Houston, USA
Eric Walker, University of Alabama at Birmingham, Center for Palliative Care, Birmingham, USA
Jeremy Woodward, Consultant Gastroenterologist, Addenbrooke's Hospital, Cambridge. UK
Reverend Caroline Worsfold, Chaplain to Northumberland Tyne & Wear NHS Trust and St Benedicts Hospice, UK
Gayle A. Sulik
Pediatric Palliative Care
Betty R. Ferrell
Psychosocial Care of Cancer Survivors
Cheryl Krauter
Cancer-related Breakthrough Pain
Learning While Caring
Samuel Hellman
Palliative care for older people
Lieve van den Block, Gwenda Albers, Sandra Martins Pereira...
Cancer Clinical Pharmacology
Jan H. M. Schellens, Howard L. McLeod, and David R. Newell
Management of Clinical Depression and Anxiety
Maggie Watson and David Kissane
Anna M. Maslin and Trevor J. Powles
Hospice Ethics
Timothy W. Kirk and Bruce Jennings
Oncology: A Case-based Manual
Paul R. Harnett, John Cartmill, and Paul Glare
Structure and Processes of Care
Gastrointestinal Symptoms in Advanced Cancer Patients
Carla Ripamonti and Eduardo Bruera
Gender in Psycho-Oncology
Youngmee Kim and Matthew J. Loscalzo
Richard LaFond
50 Studies Every Palliative Care Doctor Should Know
David Hui, Akhila Reddy, and Eduardo Bruera
Medicine & Health > Radiology > Clinical Oncology
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