(1-hydroxyethylidene)bisphosphonic acid, potassium salt
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EU Method A.6 (Water Solubility)
flask method
Water solubility:
Temp.:
The test item HEDP #13082 Nachsubstanz has a water solubility of 774 g/L at 20°C.
other: Data from MSDS
secondary literature
other: None reported
completely miscible
The substance was reported as miscible in water
The substance was reported as miscible in water in a MSDS
>= 530 g/L
ca. 7 - ca. 8.5
The substance was reported as fully miscible in water. Based on concentration of 39-43% at 20°C and since the solution density is much higher than 1, the equivalent water solubility in g/L using density and concentration is reported as ≥530 g/L.
The substance was reported as fully miscible in water in a MSDS
ca. 230 - ca. 280 g/L
ca. 5.8 - ca. 6.5
Water solubility: Commercially available HEDP-xK in the form of aqueous solution products at typically 20% w/w to 43% w/w are miscible in water.
In support of the Key data, it is notable that in general, phosphonate salts are highly hydrophilic and extremely water soluble. Free acids are less soluble than the salts; however, aqueous solutions in excess of 1% active acid material can be prepared.
In available secondary sources, HEDP-xK was reported as miscible or freely miscible in water with reported concentrations of 20 - 43% at 20°C but it is not clear from the source report whether this is expressed as %w/w, %v/v or %w/v. Since the solution density is much higher than 1, the equivalent water solubility in g/L using density and concentration is reported as ≥230 g/L. In addition, as the value is known to be extremely high, the exact value is considered not significant for the chemical safety assessment for human health or environmental assessment and this limit value is therefore sufficient and is considered to be reliable. In addition, a measured water solubility of 774 g/L at 20°C is determined for the tetrasodium salt of HEDP (HEDP-4Na) using a relevant test method. The available data are used as weight of evidence to indicate that the substance is highly soluble in water.