Initiative / COSMIC
COSMIC: Cohort Studies of Memory in an International Consortium
Studies 0
Harmonise data from international cohort studies of cognitive ageing, in order to better understand the determinants of cognitive ageing and neurocognitive disorders.
Visit COSMIC
Prof. Perminder Sachdev
Centre for Healthy Brain Ageing (CHeBA), UNSW Sydney
Perminder Sachdev
p.sachdev@unsw.edu.au
UNSW Medicine, School of Psychiatry
Dr. Darren Lipnicki
Darren Lipnicki
d.lipnicki@unsw.edu.au
UNSW Medicine
School of Psychiatry Level 1, AGSM (G27) Gate 11, Botany Street UNSW Sydney Australia
Types of cohorts
Population cohort
Worldwide (31 countries across 6 continents)
US$2.57 million from the National Institutes of Health, USA from 2017 to 2022.
Criteria of cohort's to be included
Studies participating in COSMIC typically meet the following membership criteria: 1. Are epidemiological, and therefore population-based. 2. Examine individuals aged 60 years and over. 3. Are longitudinal, either with follow-up assessments or intending to have these. 4. Include an assessment of cognitive function, cognitive impairment or dementia as an important, if not central, objective. Studies from Africa, South America, Eastern Europe and under-represented areas in Asia are particularly encouraged to join (and whom not all membership criteria necessarily need to be met).
With harmonized data
Age range of the samples
Methodology for harmonization and integration
Strategy of harmonization
Ex-post
Type of infrastructure
Data are centrally located
Integrative data analysis
Pooled analyses
Sachdev, Perminder S., et al. "COSMIC (Cohort Studies of Memory in an International Consortium): an international consortium to identify risk and protective factors and biomarkers of cognitive ageing and dementia in diverse ethnic and sociocultural groups." BMC neurology 13.1 (2013): 165. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827845/pdf/1471-2377-13-165.pdf Lipnicki, Darren M et al. "Determinants of cognitive performance and decline in 20 diverse ethno-regional groups: A COSMIC collaboration cohort study." PLoS medicine vol. 16,7 e1002853. 23 Jul. 2019, doi:10.1371/journal.pmed.1002853
Number of cohorts
Will more cohorts be harmonized?
Availability of metadata
Availability of individual data
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