The diagnosis of coccidioidomycosis
Neil M. Ampel
Until recently, culture, microscopy, and serology have been the available methods for the diagnosis of coccidioidomycosis. While Coccidioides is frequently isolated by culture, special precautions must be taken because of the risk of laboratory infection and because Coccidioides is on the Select Agent list. Serology is useful but the sensitivity remains lower than desired. A commercially available test for coccidioidal galactomannan antigenuria now exists and appears useful for immunocompromised hosts with severe disease. Polymerase chain reaction assays targeting specific coccidioidal genes have demonstrated utility but are not commercially available. Moreover, their sensitivity and the best sample type remain unestablished.
F1000 Medicine Reports
https://doi.org/10.3410/M2-2
Published - Jan 18 2010
10.3410/M2-2
Dive into the research topics of 'The diagnosis of coccidioidomycosis'. Together they form a unique fingerprint.
Coccidioides Medicine & Life Sciences 100%
Coccidioidomycosis Medicine & Life Sciences 96%
Serology Medicine & Life Sciences 69%
Laboratory Infection Medicine & Life Sciences 49%
galactomannan Medicine & Life Sciences 48%
Immunocompromised Host Medicine & Life Sciences 35%
Microscopy Medicine & Life Sciences 27%
Polymerase Chain Reaction Medicine & Life Sciences 19%
Ampel, N. M. (2010). The diagnosis of coccidioidomycosis. F1000 Medicine Reports, 2(1), [2]. https://doi.org/10.3410/M2-2
The diagnosis of coccidioidomycosis. / Ampel, Neil M.
In: F1000 Medicine Reports, Vol. 2, No. 1, 2, 18.01.2010.
Ampel, NM 2010, 'The diagnosis of coccidioidomycosis', F1000 Medicine Reports, vol. 2, no. 1, 2. https://doi.org/10.3410/M2-2
Ampel NM. The diagnosis of coccidioidomycosis. F1000 Medicine Reports. 2010 Jan 18;2(1). 2. https://doi.org/10.3410/M2-2
Ampel, Neil M. / The diagnosis of coccidioidomycosis. In: F1000 Medicine Reports. 2010 ; Vol. 2, No. 1.
@article{be65ca0fd4fb412ca7d5bb4f60691f07,
title = "The diagnosis of coccidioidomycosis",
abstract = "Until recently, culture, microscopy, and serology have been the available methods for the diagnosis of coccidioidomycosis. While Coccidioides is frequently isolated by culture, special precautions must be taken because of the risk of laboratory infection and because Coccidioides is on the Select Agent list. Serology is useful but the sensitivity remains lower than desired. A commercially available test for coccidioidal galactomannan antigenuria now exists and appears useful for immunocompromised hosts with severe disease. Polymerase chain reaction assays targeting specific coccidioidal genes have demonstrated utility but are not commercially available. Moreover, their sensitivity and the best sample type remain unestablished.",
author = "Ampel, {Neil M.}",
doi = "10.3410/M2-2",
journal = "F1000 Medicine Reports",
publisher = "Medicine Reports Limited",
T1 - The diagnosis of coccidioidomycosis
AU - Ampel, Neil M.
N2 - Until recently, culture, microscopy, and serology have been the available methods for the diagnosis of coccidioidomycosis. While Coccidioides is frequently isolated by culture, special precautions must be taken because of the risk of laboratory infection and because Coccidioides is on the Select Agent list. Serology is useful but the sensitivity remains lower than desired. A commercially available test for coccidioidal galactomannan antigenuria now exists and appears useful for immunocompromised hosts with severe disease. Polymerase chain reaction assays targeting specific coccidioidal genes have demonstrated utility but are not commercially available. Moreover, their sensitivity and the best sample type remain unestablished.
AB - Until recently, culture, microscopy, and serology have been the available methods for the diagnosis of coccidioidomycosis. While Coccidioides is frequently isolated by culture, special precautions must be taken because of the risk of laboratory infection and because Coccidioides is on the Select Agent list. Serology is useful but the sensitivity remains lower than desired. A commercially available test for coccidioidal galactomannan antigenuria now exists and appears useful for immunocompromised hosts with severe disease. Polymerase chain reaction assays targeting specific coccidioidal genes have demonstrated utility but are not commercially available. Moreover, their sensitivity and the best sample type remain unestablished.
U2 - 10.3410/M2-2
DO - 10.3410/M2-2
JO - F1000 Medicine Reports
JF - F1000 Medicine Reports
M1 - 2