Adherence to HIV antiretroviral therapy in HIV+ Ugandan patients purchasing therapy
Jayne Byakika-Tusiime, J. H. Oyugi, W. A. Tumwikirize, E. T. Katabira, P. N. Mugyenyi, David Bangsberg
Our objective was to determine the level of adherence and reasons for non-adherence to antiretroviral therapy (ART) among HIV-positive (HIV+) people on ART in a resource-limited setting. Patients receiving ART were recruited into the cross-sectional study from three treatment centres in Kampala, Uganda. The number of missed doses over the last three days was assessed by structured patient interviews and dichotomized at ±95% adherence. Reasons for non-adherence were assessed with both structured patient interviews and unstructured qualitative interviews. Independent predictors of non-adherence were assessed with multivariate logistic regression. In all, 304 HIV-infected persons on ART were enrolled into the study. Factors associated with non-adherence were marital status (odds ratio (OR) = 2.93, 95% confidence interval (CI) 1.32-6.50) and low monthly income <50 US$ [OR = 2.77, 95% CI 1.64-4.67]. We concluded that levels of self-reported adherence in patients receiving ART in Kampala are comparable to levels in resource-rich settings with inability to purchase and secure a stable supply as a major barrier to adherence.
International Journal of STD and AIDS
Patient Compliance
Antiretroviral therapy
Self-purchasing
Byakika-Tusiime, J., Oyugi, J. H., Tumwikirize, W. A., Katabira, E. T., Mugyenyi, P. N., & Bangsberg, D. (2005). Adherence to HIV antiretroviral therapy in HIV+ Ugandan patients purchasing therapy. International Journal of STD and AIDS, 16(1), 38-41. https://doi.org/10.1258/0956462052932548
Adherence to HIV antiretroviral therapy in HIV+ Ugandan patients purchasing therapy. / Byakika-Tusiime, Jayne; Oyugi, J. H.; Tumwikirize, W. A.; Katabira, E. T.; Mugyenyi, P. N.; Bangsberg, David.
In: International Journal of STD and AIDS, Vol. 16, No. 1, 01.2005, p. 38-41.
Byakika-Tusiime, J, Oyugi, JH, Tumwikirize, WA, Katabira, ET, Mugyenyi, PN & Bangsberg, D 2005, 'Adherence to HIV antiretroviral therapy in HIV+ Ugandan patients purchasing therapy', International Journal of STD and AIDS, vol. 16, no. 1, pp. 38-41. https://doi.org/10.1258/0956462052932548
Byakika-Tusiime J, Oyugi JH, Tumwikirize WA, Katabira ET, Mugyenyi PN, Bangsberg D. Adherence to HIV antiretroviral therapy in HIV+ Ugandan patients purchasing therapy. International Journal of STD and AIDS. 2005 Jan;16(1):38-41. https://doi.org/10.1258/0956462052932548
Byakika-Tusiime, Jayne ; Oyugi, J. H. ; Tumwikirize, W. A. ; Katabira, E. T. ; Mugyenyi, P. N. ; Bangsberg, David. / Adherence to HIV antiretroviral therapy in HIV+ Ugandan patients purchasing therapy. In: International Journal of STD and AIDS. 2005 ; Vol. 16, No. 1. pp. 38-41.
@article{1cc1da08838041b9afa4ec60e4c28c04,
title = "Adherence to HIV antiretroviral therapy in HIV+ Ugandan patients purchasing therapy",
abstract = "Our objective was to determine the level of adherence and reasons for non-adherence to antiretroviral therapy (ART) among HIV-positive (HIV+) people on ART in a resource-limited setting. Patients receiving ART were recruited into the cross-sectional study from three treatment centres in Kampala, Uganda. The number of missed doses over the last three days was assessed by structured patient interviews and dichotomized at ±95{\%} adherence. Reasons for non-adherence were assessed with both structured patient interviews and unstructured qualitative interviews. Independent predictors of non-adherence were assessed with multivariate logistic regression. In all, 304 HIV-infected persons on ART were enrolled into the study. Factors associated with non-adherence were marital status (odds ratio (OR) = 2.93, 95{\%} confidence interval (CI) 1.32-6.50) and low monthly income <50 US$ [OR = 2.77, 95{\%} CI 1.64-4.67]. We concluded that levels of self-reported adherence in patients receiving ART in Kampala are comparable to levels in resource-rich settings with inability to purchase and secure a stable supply as a major barrier to adherence.",
keywords = "Adherence, Antiretroviral therapy, Self-purchasing, Sub-Saharan Africa",
author = "Jayne Byakika-Tusiime and Oyugi, {J. H.} and Tumwikirize, {W. A.} and Katabira, {E. T.} and Mugyenyi, {P. N.} and David Bangsberg",
journal = "International Journal of STD and AIDS",
publisher = "SAGE Publications Ltd",
T1 - Adherence to HIV antiretroviral therapy in HIV+ Ugandan patients purchasing therapy
AU - Byakika-Tusiime, Jayne
AU - Oyugi, J. H.
AU - Tumwikirize, W. A.
AU - Katabira, E. T.
AU - Mugyenyi, P. N.
AU - Bangsberg, David
N2 - Our objective was to determine the level of adherence and reasons for non-adherence to antiretroviral therapy (ART) among HIV-positive (HIV+) people on ART in a resource-limited setting. Patients receiving ART were recruited into the cross-sectional study from three treatment centres in Kampala, Uganda. The number of missed doses over the last three days was assessed by structured patient interviews and dichotomized at ±95% adherence. Reasons for non-adherence were assessed with both structured patient interviews and unstructured qualitative interviews. Independent predictors of non-adherence were assessed with multivariate logistic regression. In all, 304 HIV-infected persons on ART were enrolled into the study. Factors associated with non-adherence were marital status (odds ratio (OR) = 2.93, 95% confidence interval (CI) 1.32-6.50) and low monthly income <50 US$ [OR = 2.77, 95% CI 1.64-4.67]. We concluded that levels of self-reported adherence in patients receiving ART in Kampala are comparable to levels in resource-rich settings with inability to purchase and secure a stable supply as a major barrier to adherence.
AB - Our objective was to determine the level of adherence and reasons for non-adherence to antiretroviral therapy (ART) among HIV-positive (HIV+) people on ART in a resource-limited setting. Patients receiving ART were recruited into the cross-sectional study from three treatment centres in Kampala, Uganda. The number of missed doses over the last three days was assessed by structured patient interviews and dichotomized at ±95% adherence. Reasons for non-adherence were assessed with both structured patient interviews and unstructured qualitative interviews. Independent predictors of non-adherence were assessed with multivariate logistic regression. In all, 304 HIV-infected persons on ART were enrolled into the study. Factors associated with non-adherence were marital status (odds ratio (OR) = 2.93, 95% confidence interval (CI) 1.32-6.50) and low monthly income <50 US$ [OR = 2.77, 95% CI 1.64-4.67]. We concluded that levels of self-reported adherence in patients receiving ART in Kampala are comparable to levels in resource-rich settings with inability to purchase and secure a stable supply as a major barrier to adherence.
KW - Adherence
KW - Antiretroviral therapy
KW - Self-purchasing
KW - Sub-Saharan Africa
JO - International Journal of STD and AIDS
JF - International Journal of STD and AIDS