Tag Archives: John Radcliffe Hospital
Physical Activity for People With Dementia Fails to Slow Rate of Cognitive Impairment (BBC News / BMJ / NHS Choices)
Posted on May 18, 2018	by Dementia and Elderly Care News
Summary It has long been widely believed that physical activity would have beneficial effects in the prevention of cognitive decline and dementia. Counter-intuitive results from the Dementia and Physical Activity (DAPA) trial suggest that moderate to high intensity exercise training for … Continue reading →
Posted in BBC News, Community Care, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, Management of Condition, Models of Dementia Care, NHS Digital (Previously NHS Choices), Non-Pharmacological Treatments, Quick Insights, UK, Universal Interest	| Tagged Activities of Daily Living, Aerobic Exercise, Alzheimer's Disease Assessment Scale Cognitive Subscale (ADAS-Cog), At-Home Exercises Heavy Gardening, Bazian, BBC Health News, Behind the Headlines, Benefits of Activity, BMJ, BMJ Publishing Group Ltd, Botnar Research Centre: University of Oxford, British Medical Journal (BMJ), Carer Quality of Life and Burden, Centre for Rehabilitation Research and Centre for Statistics in Medicine: University of Oxford, CLAHRCs: NIHR Collaborations for Leadership in Applied Health Research and Care, Coventry and Warwick Partnership Trust, Coventry and Warwickshire Partnership Trust, Critical Appraisals, Dementia And Physical Activity (DAPA) Trial, Dementia Exercise Programmes, Division of Health Sciences: University of Warwick, Enjoyable Activity, Exercise Regimens, Gardening, Good Care Group, Health Related Quality of Life, Health Technology Assessment Study, Health Technology Assessments, John Radcliffe Hospital, John Radcliffe Hospital: Oxford, National Institute for Health Research (NIHR), National Institute for Health Research: Health Technology Assessment Programme, Neuropsychiatric Symptoms, NIHR CLAHRC Oxford, NIHR CLAHRC: Collaboration for Leadership in Applied Health Research and Care, NIHR Health Technology Assessment Programme, Nuffield Department of Orthopaedics Rheumatology and Musculoskeletal Sciences: University of Oxford, Oxford University, Oxford University Hospitals NHS Foundation Trust, Physical Activity, Physical Activity Prescriptions, Physical Activity Programmes, Practical Advice on Healthy Ageing (Good Care Group), Reducing Waste in the NHS, Regular Physical Activity, Six Minute Walk Test, Strength Exercises, Strength Programmes, Strength Training, Swimming, University of Oxford, University of Warwick, Upper Body Twist, Walking, Warwick Clinical Trials Unit: University of Warwick, Warwick University, Water Aerobics, Water Balance Exercises, Water Exercises	| Leave a comment
Aspirin: Stomach Bleeds Risk for Over-75s (BBC News / Lancet / NHS Choices)
Summary Persons aged over 75 taking daily aspirin following a stroke or heart attack are at higher risk of stomach bleeds than thought previously. The benefits of low dose aspirin still outweigh the risks, even in this age group. Co-prescription … Continue reading →
Posted in BBC News, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, NHS Digital (Previously NHS Choices), Pharmacological Treatments, Quick Insights, UK, Universal Interest	| Tagged adverse, Adverse Drug Events, Adverse Drug Reactions (ADRs), Adverse Drug Reactions in the Elderly, Adverse Effects, Adverse Events, Aspirin, Aspirin: Low-Dose Acetylsalicylic Acid, Aspirin: Stomach Bleeds Risk for Over-75s, BBC Health News, Behind the Headlines, Centre for Prevention of Stroke and Dementia: University of Oxford, Daily Low-Dose Aspirin, Gastrointestinal Bleeding, John Radcliffe Hospital, Lancet, Nuffield Department of Clinical Neurosciences: University of Oxford, Oxford Vascular Study, Oxford Vascular Study (OXVASC), Prophylactic Use of Aspirin, Proton Pump Inhibitors (PPIs), University of Oxford	| Leave a comment
Early Diagnosis of Parkinson's Disease and DLB Using CSF Biomarker? (BBC News / Annals of Clinical and Translational Neurology)
Summary Research at the University of Edinburgh indicates that test for synuclein, which measures how sticky this protein molecule has become (i.e. alpha-synuclein aggregation), might be the key to diagnosing accurately the early stages of both Parkinson's Disease and Dementia … Continue reading →
Posted in BBC News, Diagnosis, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, Parkinson's Disease, Scotland, UK, Universal Interest	| Tagged Abnormal Proteins (Alpha-Synuclein), Alpha-Synuclein Aggregation, Alpha-Synuclein RT-QuIC, Alpha-Synucleinopathies, Annals of Clinical and Translational Neurology, BBC Health News, Biomarker Development, Biomarkers, Biomarkers Research Programmes, Brain Bank Network (MRC), Brains for Dementia Research (BDR), Centre for Clinical Brain Sciences: Western General Hospital, Cerebrospinal Fluid Biomarkers for Parkinson's Disease Diagnosis, Creutzfeldt Jacob Disease (CJD), Creutzfeldt-Jakob Disease (CJD), Creutzfeldt-Jakob Disease in United Kingdom Patients Treated With Human Pituitary Growth Hormone, CSF Biomarkers, Dementia With Lewy Bodies (DLB), Department of Physiology Anatomy and Genetics: University of Oxford, Diagnosis, Diagnosis and Screening: Dementia with Lewy Bodies, Differential Diagnosis, DLB: Dementia with Lewy Bodies, Early Diagnosis, Early Diagnosis of Lewy Body Dementia (LBD), Early Diagnosis of Parkinson's Disease, Early Diagnosis of Parkinson's Disease and DLB, Edinburgh Brain Bank, α-Synuclein, α-Synuclein Aggregation, α-Synuclein Misfolds, John Radcliffe Hospital, Lewy Body Degeneration, Lewy Body Dementia, Lewy Body Dementia (LBD), Medical Research Council (MRC), Michael J Fox Foundation, Misfolded Proteins, Monument Trust Discovery Award (Parkinson's UK), MRC Brain Bank, National CJD Research and Surveillance Unit (NCJDRSU), National CJD Surveillance Unit: Western General Hospital: Data Release (HSCIC), National Institute for Health Research (NIHR), National Institute for Health Research (NIHR) Oxford Biomedical Research Centre, NCJDRSU: National CJD Research and Surveillance Unit, Neurodegenerative Disease Research, Neurodegenerative Diseases, Neurodegenerative Disorders, Nuffield Department of Clinical Neurosciences: University of Oxford, OPDC Discovery Cohort, OPTIMA Cohort, OPTIMA Cohort (Oxford Project to Investigate Memory and Ageing), Oxford Brain Bank, Oxford Parkinson's Disease Centre, Oxford Parkinson's Disease Centre (OPDC) Discovery Study, Oxford Parkinson's Disease Centre: University of Oxford, Preclinical Biomarkers and Dementia, Prion-Like Mechanisms, Real-Time Quaking-Induced Conversion (RT-QuIC) Based Assay, Scottish Government's Chief Scientists Office, Sporadic Creutzfeldt-Jakob Disease, Synucleinopathies, Synucleinopathy, Synucleinopathy Progression, UK Brain Banks Network, UK Parkinson's Disease Society Brain Bank Clinical Diagnostic Criteria, Underlying Mechanisms of DLB Pathogenesis, University of Edinburgh, University of Oxford, Western General Hospital: Edinburgh	| Leave a comment
Possible Link Between Alzheimer's Disease and Schizophrenia? (BBC News / PNAS)
Summary A "weak spot" in the brain, which may be play some common role(s) underlying both Alzheimer's Disease and schizophrenia, appears to have been identified using functional Magnetic Resonance Imaging (fMRI) brain scans. The brain area in question has been … Continue reading →
Posted in BBC News, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), In the News, International, Mental Health, Quick Insights, UK, Universal Interest	| Tagged BBC Health News, Brain Scans, Bristol Brain Bank, California Verbal Learning Test (CVLT), Dementia Praecox (Old Medical Nomeclature), Dementia Praecox (Premature Dementia or Precocious Madness), Department of Neurology: University Hospital Mannheim, Division of Brain Sciences: Imperial College London, Division of Mental Health and Addiction: Oslo University Hospital, Felix Platter-Hospital (Basel), fMRI, Functional Magnetic Resonance Imaging (fMRI), Functional Magnetic Resonance Imaging of the Brain (FMRIB) Centre: University of Oxford, Genetic Risk Factors, Germany, Heidelberg, Human Connectome Project (HCP), Human Connectome Project (HCP) Consortium, Imperial College London, Induced Pluripotent Stem Cells (iPSCs), Institute of Psychiatry Psychology and Neuroscience at King's College London, John Radcliffe Hospital, KG Jebsen Centre for Psychosis Research: Oslo University Hospital, Kings College London, Medical Research Council (MRC), Medical Research Council's Laboratory of Molecular Biology, Memory Clinic: University Center for Medicine of Aging Basel, MRC: Medical Research Council, MRI Brain Imaging, MRI Scans, Neural Networks, Neurodegeneration, Neurodegenerative Diseases, Neurodegenerative Research, Neuroimaging, Neuroimaging in Dementia Diagnosis, Neuroimaging of De­mentia, Neuroimaging of Neuropsychiatric Disorders (Human Connectome Project), Neuroscience, Norway, Norwegian Centre for Mental Disorders Research (NORMENT): Oslo University Hospital, Novel Targets in Neurodegeneration, Nuffield Department of Clinical Neurosciences: University of Oxford, Organoids (Madeline Lancaster), Oslo, PNAS, Potential Link Between Alzheimer's Disease and Schizophrenia, Premature Dementia (Old Medical Nomeclature), Proceedings of the National Academy of Sciences (PNAS), Proceedings of the National Academy of Sciences of the United States of America (PNAS), Professor Ed Bullmore: Head of Psychiatry at University of Cambridge, Professor Ed Bullmore: Vice-President of ImmunoPsychiatry at GSK, Research Group for Life-Span Changes in Brain and Cognition: University of Oslo, Schizophrenia, Switzerland, UK Brain Banks Network, UK Medical Research Council's Laboratory of Molecular Biology, University Center for Medicine of Aging Basel: Felix Platter-Hospital, University College London, University College London (UCL), University Hospital Mannheim, University of Cambridge, University of Heidelberg, University of Oslo, University of Oxford, Wechsler Abbreviated Scale of Intelligence (WASI)	| Leave a comment
Further Dementia Diagnostic Test Accuracy Systematic Review Protocols (Cochrane Database)
Summary This is an additional list of diagnostic testing-related protocols, further to the Cochrane Dementia and Cognitive Improvement Group (CDCIG) Diagnostic Test Accuracy (DTA) protocols and protocol templates listed earlier in Generic Protocol(s) for Diagnostic Test Accuracy Reviews in Dementia … Continue reading →
Posted in Diagnosis, For Doctors (mostly), For Nurses and Therapists (mostly), For Researchers (mostly), Models of Dementia Care, NIHR, Systematic Reviews, UK	| Tagged 11C-PIB-PET, 18FDG-PET, 6-Item Cognitive Impairment Test (6-CIT), Abbreviated Mental Test (AMT), Addenbrooke's Cognitive Exaination-Revised (ACE-R), ALOIS: the Cochrane Dementia and Cognitive Improvement Group, APOE e4 (Apolipoprotein E e4), APOE-4 Allele, Asymptomatic Alzheimer's Disease, Blessed Information-Memory-Concentration Test (Blessed I-M-C), Brain Imaging, Bristol University, Canada, CDCIG: Cochrane Dementia and Cognitive Improvement Group, Central and North West London NHS Foundation Trust, China, China Medical University, Clinical Cooperation Unit Nuclear Medicine (Heidelberg), Clock Drawing Test (CDT), Cochrane Dementia and Cognitive Improvement Group (CDCIG), Cochrane Diagnostic Test Accuracy (DTA) Dementia Reviews, Cochrane Diagnostic Test Accuracy (DTA) Reviews, Cochrane Diagnostic Test Accuracy Review Unit (DTA Unit), Cognitive Assessments / Screening Tools, CSF (Cerebrospinal Fluid Analysis of Amyloid Beta and Tau), CSF Tau, CSF Tau / ABeta Ratio, Department of Neurology: VU University Medical Centre Amsterdam, Devon, Diagnostic Test Accuracy (DTA) Handbook, Diagnostic Test Accuracy Reviews, Differential Diagnosis, Differential Diagnosis of Alzheimer's Disease, Dopamine Transporter Imaging, Dopamine Transporter Imaging (for Diagnosis of DLB), DTA Handbook, Early Differential Diagnosis, Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta: Neuroepidemiology Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, FP-CIT (Fluoropropyl-Carbomethoxy-3b-(4-Iodophenyl)Tropane), Frenchay Hospital (Bristol), Frontotemporal Dementia (FTD), Generic Protocols for Cross-Sectional and Delayed-Verification Studies, German Cancer Research Center: Medical PET Group - Biological Imaging, Germany, Glasgow Royal Infirmary, GP-Cog, Imaging, Imperial College London, Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE), Institute of Cardiovascular and Medical Sciences: Glasgow, Institute of Cardiovascular and Medical Sciences: University of Glasgow, Institute of Health Research: Exeter, Institute of Public Health (Cambridge UK), Institute of Public Health (IPH), Institute of Public Health: Cambridge, IRCCS Fatebenefratelli (Brescia), Italy, John Radcliffe Hospital, LITA Polo Universitario, Maastricht University, Maastricht University: Department of Psychiatry and Neuropsychology, Mini-Cog, Modified Mini-Mental State Examination (3-MS), MRI, MRI Brain Imaging, MRI Scans, National Institute for Health Research (NIHR) Cochrane Collaboration Programme, Netherlands, Neuroimaging in Dementia Diagnosis, Neuropsychological Tests for Alzheimer's Disease Diagnosis, Neuropsychological Tests for Dementia Diagnosis, North Bristol NHS Trust, Nuffield Department of Clinical Neurosciences (Oxford), Nuffield Department of Clinical Neurosciences: University of Oxford, Nuffield Department of Medicine (Oxford), Older People and Healthy Ageing Service Line (London), OPTIMA (Oxford Project to Investigate Memory and Ageing), OPTIMA (Oxfordshire UK), Ospedale Luigi Sacco, Oxford, Oxford Health NHS Foundation Trust, Oxford University Hospitals NHS Trust, Oxford University Medical School, PenCLAHRC, Peninsula CLAHRC, Peninsula Technology Assessment Group (PenTAG), PET-FDG (Positron Emission Tomography F-Fluorodeoxyglucose), PET-PiB (Positron Emission Tomography-Pittsburgh Compound B), Plasma and Cerebrospinal Fluid (CSF) Abeta42, Positron Emission Tomography (PET), Protocols, Public Health Epidemiology and Biostatistics: Birmingham, Queen's University (Canada), Radcliffe Department of Medicine, ratio, rCBF SPECT, Research Protocol, School for Mental Health and Neuroscience: Maastricht University, Shengjing Hospital, sMRI (Structural Magnetic Resonance Imaging), SPECT (Single Photon Emission Computed Tomography), St Louis University Mental Status Examination (SLUMS), Study Protocol, Sunnybrook Health Sciences Centre (Toronto), Systematic Reviews and Meta-Analyses, Test Your Memory (TYM), University Hospitals Bristol, University of Birmingham, University of Bristol, University of Cambridge, University of Exeter, University of Exeter Medical School, University of Glasgow, University of Milan, University of Oxford, University of Toronto, VU University (Netherlands), VU University Medical Centre	| Leave a comment
Cholinesterase Inhibitors for Dementia with Lewy Bodies, Parkinson's Disease Dementia and Cognitive Impairment in Parkinson's Disease (Cochrane Library)
Posted on April 4, 2012	by Dementia and Elderly Care News
[A version of this item appears in: Dementia: the Latest Evidence Newsletter (RWHT), Volume 2 Issue 9, April 2012]. Summary Earlier Cochrane reviews have examined the use of cholinesterase inhibitors in both Parkinson's Disease with dementia (PDD) and dementia with … Continue reading →
Posted in Acute Hospitals, Community Care, For Doctors (mostly), For Researchers (mostly), Pharmacological Treatments, Systematic Reviews, Universal Interest	| Tagged Acetylcholine, ADCS (Scale), ALOIS: the Cochrane Dementia and Cognitive Improvement Group, Behavioural Disturbance Rating Scales, Cholinesterase Inhibitors, CIND-PD: Cognitive Impairment in Parkinson's Disease, Cognitive Impairment in Parkinson's Disease, Cognitive Impairment in Parkinson's Disease (CIND-PD), Dementia with Lewy Bodies, DLB: Dementia with Lewy Bodies, Donepezil, Donepezil (Aricept), John Radcliffe Hospital, Mini Mental State Examination (MMSE), Oxford University Hospitals NHS Trust, Parkinson's Disease Dementia, Parkinsonian Symptoms, PDD: Parkinson's Disease with Dementia, Rivastigmine, Unified Parkinson's Disease Rating Scale (UPDRS)	| Leave a comment