MedGenMed Pulmonary Medicine
Cystic Fibrosis and Nasal Polyposis
Ford D. Albritton IV, MD, and Todd T. Kingdom, MD, Emory University, Atlanta, Ga.
Surgical Therapy
Future Horizons
Nasal polyposis is a sinonasal manifestation of cystic fibrosis (CF)--an autosomal recessive exocrinopathy. Up to 67% of all CF patients will manifest polyps in their lifetime. Symptoms include nasal airway obstruction, anosmia, rhinorrhea, and exacerbation of the rhinosinusitis that affects these patients. The polyps are probably a consequence of chronic inflammation; however, their specific etiology is unclear. Treatment includes antibiotics, topical nasal steroids, decongestants, and mucolytics. Surgery is necessary when conservative measures fail. Endoscopic sinus surgery (ESS) has replaced traditional treatments such as intranasal polypectomy and Caldwell-Luc procedure. ESS combined with medical therapy has successfully delayed the time to recurrence, decreased the need for surgery, and improved the underlying pulmonary status in several studied patient groups. This article reviews typical patient symptoms, physical examination, the use of computed tomography (CT), nasal endoscopic findings, patient prognosis, and the latest research and innovations.
© 2000 Medscape
Cite this: Cystic Fibrosis and Nasal Polyposis - Medscape - Feb 18, 2000.
Dr. Albritton is a resident physician and Dr. Kingdom is Assistant Professor in the Department of Otolaryngology at Emory University School of Medicine, Atlanta, Ga.
Albritton FD, Kingdom TT. Cystic Fibrosis and Nasal Polyposis. MedGenMed 2(1), 2000 [formerly published in Medscape Pulmonary Medicine eJournal 4(1), 2000]. Available at: http://www.medscape.com/viewarticle/408749
Procedures Nasal Polyp Surgery
Procedures Sinonasal Manifestations of Cystic Fibrosis
Clinical Case Drinking Beer Worsens Nasal Symptoms in a 35-Year-Old Man
Diseases & Conditions Pediatric Nasal Polyps
Drugs Related to null
telaprevir
According to PULMONOLOGISTS
A 47-Year-Old With Progressive Dyspnea and Weepy Nodules
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