Liver fibrosis in asymptomatic polyvinyl chloride workers
Tun Jen Hsiaos, Jung Der Wang, Pei Wing Yang, Pei Cheng Yang, Tsun Jen Cheng
This study was designed to determine whether vinyl chloride monomer (VCM) exposure is associated with liverfibrosis. A total of 347 workers with occupational exposure to VCM were systemically examined using liver ultrasonography and routine liver function tests. Vinyl chloride monomer cumulative dose (ppm-month) was estimated by summing the products of air VCM concentration levels and months of employment. Liver fibrosis was defined in subjects with precirrhosis and cirrhosis of liver diagnosed using ultrasonography. Significantly increased risks of developing liver fibrosis were found in workers who had history of high exposure jobs (odds ratio 5.5, 95% confidence interval 1.7-25.4) when compared with workers who did not have history of high exposure jobs. We concluded that there was an increased risk of developing liver fibrosis in PVC workers who had high exposure to VCM.
Journal of Occupational and Environmental Medicine
https://doi.org/10.1097/01.jom.0000137722.66767.38
10.1097/01.jom.0000137722.66767.38
Dive into the research topics of 'Liver fibrosis in asymptomatic polyvinyl chloride workers'. Together they form a unique fingerprint.
Vinyl Chloride Medicine & Life Sciences 100%
Polyvinyl Chloride Medicine & Life Sciences 88%
Occupational Groups Medicine & Life Sciences 47%
worker Social Sciences 41%
Ultrasonography Medicine & Life Sciences 20%
Liver Function Tests Medicine & Life Sciences 15%
history Social Sciences 14%
Occupational Exposure Medicine & Life Sciences 14%
Hsiaos, T. J., Wang, J. D., Yang, P. W., Yang, P. C., & Cheng, T. J. (2004). Liver fibrosis in asymptomatic polyvinyl chloride workers. Journal of Occupational and Environmental Medicine, 46(9), 962-966. https://doi.org/10.1097/01.jom.0000137722.66767.38
Hsiaos, Tun Jen ; Wang, Jung Der ; Yang, Pei Wing et al. / Liver fibrosis in asymptomatic polyvinyl chloride workers. In: Journal of Occupational and Environmental Medicine. 2004 ; Vol. 46, No. 9. pp. 962-966.
@article{6b394e2d900a466b934ee24fd5c29e68,
title = "Liver fibrosis in asymptomatic polyvinyl chloride workers",
abstract = "This study was designed to determine whether vinyl chloride monomer (VCM) exposure is associated with liverfibrosis. A total of 347 workers with occupational exposure to VCM were systemically examined using liver ultrasonography and routine liver function tests. Vinyl chloride monomer cumulative dose (ppm-month) was estimated by summing the products of air VCM concentration levels and months of employment. Liver fibrosis was defined in subjects with precirrhosis and cirrhosis of liver diagnosed using ultrasonography. Significantly increased risks of developing liver fibrosis were found in workers who had history of high exposure jobs (odds ratio 5.5, 95% confidence interval 1.7-25.4) when compared with workers who did not have history of high exposure jobs. We concluded that there was an increased risk of developing liver fibrosis in PVC workers who had high exposure to VCM.",
author = "Hsiaos, {Tun Jen} and Wang, {Jung Der} and Yang, {Pei Wing} and Yang, {Pei Cheng} and Cheng, {Tsun Jen}",
doi = "10.1097/01.jom.0000137722.66767.38",
journal = "Journal of Occupational and Environmental Medicine",
Hsiaos, TJ, Wang, JD, Yang, PW, Yang, PC & Cheng, TJ 2004, 'Liver fibrosis in asymptomatic polyvinyl chloride workers', Journal of Occupational and Environmental Medicine, vol. 46, no. 9, pp. 962-966. https://doi.org/10.1097/01.jom.0000137722.66767.38
Liver fibrosis in asymptomatic polyvinyl chloride workers. / Hsiaos, Tun Jen; Wang, Jung Der; Yang, Pei Wing et al.
In: Journal of Occupational and Environmental Medicine, Vol. 46, No. 9, 09.2004, p. 962-966.
T1 - Liver fibrosis in asymptomatic polyvinyl chloride workers
AU - Hsiaos, Tun Jen
AU - Wang, Jung Der
AU - Yang, Pei Wing
AU - Yang, Pei Cheng
AU - Cheng, Tsun Jen
N2 - This study was designed to determine whether vinyl chloride monomer (VCM) exposure is associated with liverfibrosis. A total of 347 workers with occupational exposure to VCM were systemically examined using liver ultrasonography and routine liver function tests. Vinyl chloride monomer cumulative dose (ppm-month) was estimated by summing the products of air VCM concentration levels and months of employment. Liver fibrosis was defined in subjects with precirrhosis and cirrhosis of liver diagnosed using ultrasonography. Significantly increased risks of developing liver fibrosis were found in workers who had history of high exposure jobs (odds ratio 5.5, 95% confidence interval 1.7-25.4) when compared with workers who did not have history of high exposure jobs. We concluded that there was an increased risk of developing liver fibrosis in PVC workers who had high exposure to VCM.
AB - This study was designed to determine whether vinyl chloride monomer (VCM) exposure is associated with liverfibrosis. A total of 347 workers with occupational exposure to VCM were systemically examined using liver ultrasonography and routine liver function tests. Vinyl chloride monomer cumulative dose (ppm-month) was estimated by summing the products of air VCM concentration levels and months of employment. Liver fibrosis was defined in subjects with precirrhosis and cirrhosis of liver diagnosed using ultrasonography. Significantly increased risks of developing liver fibrosis were found in workers who had history of high exposure jobs (odds ratio 5.5, 95% confidence interval 1.7-25.4) when compared with workers who did not have history of high exposure jobs. We concluded that there was an increased risk of developing liver fibrosis in PVC workers who had high exposure to VCM.
U2 - 10.1097/01.jom.0000137722.66767.38
DO - 10.1097/01.jom.0000137722.66767.38
JO - Journal of Occupational and Environmental Medicine
JF - Journal of Occupational and Environmental Medicine
Hsiaos TJ, Wang JD, Yang PW, Yang PC, Cheng TJ. Liver fibrosis in asymptomatic polyvinyl chloride workers. Journal of Occupational and Environmental Medicine. 2004 Sep;46(9):962-966. doi: 10.1097/01.jom.0000137722.66767.38