Laboratory diagnosis of clostridium difficile infection in korea: The first national survey
Hae Sun Chung, Jeong Su Park, Bo Moon Shin
Department of Laboratory Medicine
In May 2015, we conducted a voluntary online survey on laboratory diagnostic assays for Clostridium difficile infection (CDI) across clinical microbiology laboratories in Korea. Responses were obtained from 66 laboratories, including 61 hospitals and five commercial laboratories. Among them, nine laboratories reported having not conducted CDI assays. The toxin AB enzyme immunoassay (toxin AB EIA), nucleic acid amplification test (NAAT), and C. difficile culture, alone or in combination with other assays, were used in 51 (89.5%), 37 (64.9%), and 37 (64.9%) of the remaining 57 laboratories, respectively, and 23 (40.4%) of the laboratories performed all three assays. Only one laboratory used the glutamate dehydrogenase assay. Nine laboratories used the toxin AB EIA as a stand-alone assay. The median (range) of examined specimens in one month for the toxin AB EIA, NAAT, and C. difficile culture was 160 (50-2,060), 70 (7-720), and 130 (9-750), respectively. These findings serve as valuable basic data regarding the current status of laboratory diagnosis of CDI in Korea, offering guidance for improved implementation.
Annals of Laboratory Medicine
https://doi.org/10.3343/alm.2019.39.3.317
Nucleic acid amplification test
Toxin ab enzyme immunoassay
10.3343/alm.2019.39.3.317
Dive into the research topics of 'Laboratory diagnosis of clostridium difficile infection in korea: The first national survey'. Together they form a unique fingerprint.
Clostridium Infections Medicine & Life Sciences 100%
Clinical Laboratory Techniques Medicine & Life Sciences 89%
Toxin Chemical Compounds 76%
Nucleic Acid Chemical Compounds 44%
Immunoenzyme Techniques Medicine & Life Sciences 27%
Nucleic Acid Amplification Techniques Medicine & Life Sciences 25%
Clostridium difficile Medicine & Life Sciences 21%
Chung, H. S., Park, J. S., & Shin, B. M. (2019). Laboratory diagnosis of clostridium difficile infection in korea: The first national survey. Annals of Laboratory Medicine, 39(3), 317-321. https://doi.org/10.3343/alm.2019.39.3.317
Chung, Hae Sun ; Park, Jeong Su ; Shin, Bo Moon. / Laboratory diagnosis of clostridium difficile infection in korea : The first national survey. In: Annals of Laboratory Medicine. 2019 ; Vol. 39, No. 3. pp. 317-321.
@article{d219d56d7de94d4eaf8c024ce5c4f496,
title = "Laboratory diagnosis of clostridium difficile infection in korea: The first national survey",
abstract = "In May 2015, we conducted a voluntary online survey on laboratory diagnostic assays for Clostridium difficile infection (CDI) across clinical microbiology laboratories in Korea. Responses were obtained from 66 laboratories, including 61 hospitals and five commercial laboratories. Among them, nine laboratories reported having not conducted CDI assays. The toxin AB enzyme immunoassay (toxin AB EIA), nucleic acid amplification test (NAAT), and C. difficile culture, alone or in combination with other assays, were used in 51 (89.5%), 37 (64.9%), and 37 (64.9%) of the remaining 57 laboratories, respectively, and 23 (40.4%) of the laboratories performed all three assays. Only one laboratory used the glutamate dehydrogenase assay. Nine laboratories used the toxin AB EIA as a stand-alone assay. The median (range) of examined specimens in one month for the toxin AB EIA, NAAT, and C. difficile culture was 160 (50-2,060), 70 (7-720), and 130 (9-750), respectively. These findings serve as valuable basic data regarding the current status of laboratory diagnosis of CDI in Korea, offering guidance for improved implementation.",
keywords = "Clostridium difficile infection, Culture, Korea, Laboratory diagnosis, Nucleic acid amplification test, Survey, Toxin ab enzyme immunoassay",
author = "Chung, {Hae Sun} and Park, {Jeong Su} and Shin, {Bo Moon}",
note = "Publisher Copyright: {\textcopyright} 2019 Seoul National University. All rights reserved.",
doi = "10.3343/alm.2019.39.3.317",
journal = "Annals of Laboratory Medicine",
publisher = "Seoul National University",
Chung, HS, Park, JS & Shin, BM 2019, 'Laboratory diagnosis of clostridium difficile infection in korea: The first national survey', Annals of Laboratory Medicine, vol. 39, no. 3, pp. 317-321. https://doi.org/10.3343/alm.2019.39.3.317
Laboratory diagnosis of clostridium difficile infection in korea : The first national survey. / Chung, Hae Sun; Park, Jeong Su; Shin, Bo Moon.
In: Annals of Laboratory Medicine, Vol. 39, No. 3, 2019, p. 317-321.
T1 - Laboratory diagnosis of clostridium difficile infection in korea
T2 - The first national survey
AU - Chung, Hae Sun
AU - Park, Jeong Su
AU - Shin, Bo Moon
N1 - Publisher Copyright: © 2019 Seoul National University. All rights reserved.
N2 - In May 2015, we conducted a voluntary online survey on laboratory diagnostic assays for Clostridium difficile infection (CDI) across clinical microbiology laboratories in Korea. Responses were obtained from 66 laboratories, including 61 hospitals and five commercial laboratories. Among them, nine laboratories reported having not conducted CDI assays. The toxin AB enzyme immunoassay (toxin AB EIA), nucleic acid amplification test (NAAT), and C. difficile culture, alone or in combination with other assays, were used in 51 (89.5%), 37 (64.9%), and 37 (64.9%) of the remaining 57 laboratories, respectively, and 23 (40.4%) of the laboratories performed all three assays. Only one laboratory used the glutamate dehydrogenase assay. Nine laboratories used the toxin AB EIA as a stand-alone assay. The median (range) of examined specimens in one month for the toxin AB EIA, NAAT, and C. difficile culture was 160 (50-2,060), 70 (7-720), and 130 (9-750), respectively. These findings serve as valuable basic data regarding the current status of laboratory diagnosis of CDI in Korea, offering guidance for improved implementation.
AB - In May 2015, we conducted a voluntary online survey on laboratory diagnostic assays for Clostridium difficile infection (CDI) across clinical microbiology laboratories in Korea. Responses were obtained from 66 laboratories, including 61 hospitals and five commercial laboratories. Among them, nine laboratories reported having not conducted CDI assays. The toxin AB enzyme immunoassay (toxin AB EIA), nucleic acid amplification test (NAAT), and C. difficile culture, alone or in combination with other assays, were used in 51 (89.5%), 37 (64.9%), and 37 (64.9%) of the remaining 57 laboratories, respectively, and 23 (40.4%) of the laboratories performed all three assays. Only one laboratory used the glutamate dehydrogenase assay. Nine laboratories used the toxin AB EIA as a stand-alone assay. The median (range) of examined specimens in one month for the toxin AB EIA, NAAT, and C. difficile culture was 160 (50-2,060), 70 (7-720), and 130 (9-750), respectively. These findings serve as valuable basic data regarding the current status of laboratory diagnosis of CDI in Korea, offering guidance for improved implementation.
KW - Clostridium difficile infection
KW - Culture
KW - Korea
KW - Laboratory diagnosis
KW - Nucleic acid amplification test
KW - Survey
KW - Toxin ab enzyme immunoassay
U2 - 10.3343/alm.2019.39.3.317
DO - 10.3343/alm.2019.39.3.317
JO - Annals of Laboratory Medicine
JF - Annals of Laboratory Medicine
Chung HS, Park JS, Shin BM. Laboratory diagnosis of clostridium difficile infection in korea: The first national survey. Annals of Laboratory Medicine. 2019;39(3):317-321. doi: 10.3343/alm.2019.39.3.317