Monitoring the impact of a national HPV vaccination program in Japan (MINT Study): rationale, design and methods
MINT Study Group
医学系研究科・医科学専攻
We have developed a collaborative hospital-based approach to monitoring the impact of a human papillomavirus vaccine on cervical cancer, its precursor lesions and human papillomavirus type-specific prevalence in Japan. The monitoring will be conducted for a total period of 21 years on women aged <40 who are newly diagnosed with invasive cervical cancer, cervical intraepithelial neoplasia or adenocarcinoma in situ at 21 participating institutes. Women are monitored to determine their vaccine history and will be human papillomavirus-genotyped each year. The primary endpoint is the human papillomavirus16/human papillomavirus18-positive rate in women aged 16-25 who are diagnosed with invasive cervical cancer, cervical intraepithelial neoplasia grade 2/3 and adenocarcinoma in situ. The major secondary endpoints are the number of women aged <40 who are diagnosed with invasive cervical cancer, cervical intraepithelial neoplasia grade 2/3 and adenocarcinoma in situ, the human papillomavirus type-specific prevalence, and the number of deaths from invasive cervical cancer in women aged <40. Long-term surveillance for human papillomavirus-associated cervical diseases in young females is important for the development of future strategies for cervical cancer prevention in Japan.
https://doi.org/10.1093/jjco/hyu097
腫瘍学
癌研究
この成果は、次の持続可能な開発目標に貢献しています
10.1093/jjco/hyu097
「Monitoring the impact of a national HPV vaccination program in Japan (MINT Study): rationale, design and methods」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。
Woman Nursing and Health Professions 100%
Uterine Cervix Cancer Nursing and Health Professions 50%
Cervical Cancer Medicine and Dentistry 50%
Wart Virus Medicine and Dentistry 40%
Adenocarcinoma in Situ Medicine and Dentistry 40%
Uterine Cervix Carcinoma in Situ Nursing and Health Professions 30%
Cervical Intraepithelial Neoplasia Medicine and Dentistry 30%
Prevalence Nursing and Health Professions 20%
MINT Study Group (2014). Monitoring the impact of a national HPV vaccination program in Japan (MINT Study): rationale, design and methods. Japanese journal of clinical oncology, 44(10), 1000-1003. https://doi.org/10.1093/jjco/hyu097
Monitoring the impact of a national HPV vaccination program in Japan (MINT Study) : rationale, design and methods. / MINT Study Group.
In: Japanese journal of clinical oncology, Vol. 44, No. 10, 01.10.2014, p. 1000-1003.
MINT Study Group 2014, 'Monitoring the impact of a national HPV vaccination program in Japan (MINT Study): rationale, design and methods', Japanese journal of clinical oncology, vol. 44, no. 10, pp. 1000-1003. https://doi.org/10.1093/jjco/hyu097
MINT Study Group. Monitoring the impact of a national HPV vaccination program in Japan (MINT Study): rationale, design and methods. Japanese journal of clinical oncology. 2014 10月 1;44(10):1000-1003. doi: 10.1093/jjco/hyu097
MINT Study Group. / Monitoring the impact of a national HPV vaccination program in Japan (MINT Study) : rationale, design and methods. In: Japanese journal of clinical oncology. 2014 ; Vol. 44, No. 10. pp. 1000-1003.
@article{9059b79093a542a2a3fbedb02d379d70,
title = "Monitoring the impact of a national HPV vaccination program in Japan (MINT Study): rationale, design and methods",
abstract = "We have developed a collaborative hospital-based approach to monitoring the impact of a human papillomavirus vaccine on cervical cancer, its precursor lesions and human papillomavirus type-specific prevalence in Japan. The monitoring will be conducted for a total period of 21 years on women aged <40 who are newly diagnosed with invasive cervical cancer, cervical intraepithelial neoplasia or adenocarcinoma in situ at 21 participating institutes. Women are monitored to determine their vaccine history and will be human papillomavirus-genotyped each year. The primary endpoint is the human papillomavirus16/human papillomavirus18-positive rate in women aged 16-25 who are diagnosed with invasive cervical cancer, cervical intraepithelial neoplasia grade 2/3 and adenocarcinoma in situ. The major secondary endpoints are the number of women aged <40 who are diagnosed with invasive cervical cancer, cervical intraepithelial neoplasia grade 2/3 and adenocarcinoma in situ, the human papillomavirus type-specific prevalence, and the number of deaths from invasive cervical cancer in women aged <40. Long-term surveillance for human papillomavirus-associated cervical diseases in young females is important for the development of future strategies for cervical cancer prevention in Japan.",
keywords = "cervical cancer, cervical intraepithelial neoplasia, human papillomavirus, vaccination",
author = "{MINT Study Group} and Koji Matsumoto and Nobuo Yaegashi and Takashi Iwata and Kazuya Ariyoshi and Kiyoshi Fujiwara and Yuko Shiroyama and Tomoka Usami and Yoshiaki Kawano and Koji Horie and Kouichiro Kawano and Kiichiro Noda and Hiroyuki Yoshikawa",
note = "Publisher Copyright: {\textcopyright} The Author 2014. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.",
doi = "10.1093/jjco/hyu097",
T1 - Monitoring the impact of a national HPV vaccination program in Japan (MINT Study)
T2 - rationale, design and methods
AU - MINT Study Group
AU - Matsumoto, Koji
AU - Yaegashi, Nobuo
AU - Iwata, Takashi
AU - Ariyoshi, Kazuya
AU - Fujiwara, Kiyoshi
AU - Shiroyama, Yuko
AU - Usami, Tomoka
AU - Kawano, Yoshiaki
AU - Horie, Koji
AU - Kawano, Kouichiro
AU - Noda, Kiichiro
AU - Yoshikawa, Hiroyuki
N1 - Publisher Copyright: © The Author 2014. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.
N2 - We have developed a collaborative hospital-based approach to monitoring the impact of a human papillomavirus vaccine on cervical cancer, its precursor lesions and human papillomavirus type-specific prevalence in Japan. The monitoring will be conducted for a total period of 21 years on women aged <40 who are newly diagnosed with invasive cervical cancer, cervical intraepithelial neoplasia or adenocarcinoma in situ at 21 participating institutes. Women are monitored to determine their vaccine history and will be human papillomavirus-genotyped each year. The primary endpoint is the human papillomavirus16/human papillomavirus18-positive rate in women aged 16-25 who are diagnosed with invasive cervical cancer, cervical intraepithelial neoplasia grade 2/3 and adenocarcinoma in situ. The major secondary endpoints are the number of women aged <40 who are diagnosed with invasive cervical cancer, cervical intraepithelial neoplasia grade 2/3 and adenocarcinoma in situ, the human papillomavirus type-specific prevalence, and the number of deaths from invasive cervical cancer in women aged <40. Long-term surveillance for human papillomavirus-associated cervical diseases in young females is important for the development of future strategies for cervical cancer prevention in Japan.
AB - We have developed a collaborative hospital-based approach to monitoring the impact of a human papillomavirus vaccine on cervical cancer, its precursor lesions and human papillomavirus type-specific prevalence in Japan. The monitoring will be conducted for a total period of 21 years on women aged <40 who are newly diagnosed with invasive cervical cancer, cervical intraepithelial neoplasia or adenocarcinoma in situ at 21 participating institutes. Women are monitored to determine their vaccine history and will be human papillomavirus-genotyped each year. The primary endpoint is the human papillomavirus16/human papillomavirus18-positive rate in women aged 16-25 who are diagnosed with invasive cervical cancer, cervical intraepithelial neoplasia grade 2/3 and adenocarcinoma in situ. The major secondary endpoints are the number of women aged <40 who are diagnosed with invasive cervical cancer, cervical intraepithelial neoplasia grade 2/3 and adenocarcinoma in situ, the human papillomavirus type-specific prevalence, and the number of deaths from invasive cervical cancer in women aged <40. Long-term surveillance for human papillomavirus-associated cervical diseases in young females is important for the development of future strategies for cervical cancer prevention in Japan.
KW - cervical cancer
KW - cervical intraepithelial neoplasia
KW - human papillomavirus
U2 - 10.1093/jjco/hyu097
DO - 10.1093/jjco/hyu097