Relapse of multiple myeloma presenting as lower lip numbness
Yusra M. Al-Riyami, Abdulaziz Bakathir, Khalil Al-Farsi, Faisal Al-Azri
Radiology & Molecular Imaging
Multiple myeloma (MM) is an uncommon malignancy characterised by the proliferation of clonal plasma cells. There are few published reports describing the extramedullary presentation of MM manifesting primarily in the head and neck region. In addition, the occurrence of an isolated relapse of MM in these sites is exceedingly rare. We report a 56-year-old female who presented to the Sultan Qaboos University Hospital, Muscat, Oman, in 2010 with sudden-onset numbness of the lower lip. She had a history of MM in remission following chemotherapy and a bone marrow transplant. Clinical and radiographic examinations were indicative of a possible relapse of MM, which was subsequently confirmed by bone marrow aspiration and histopathological evaluation. This unique case highlights the unusual site of relapse of a haematolymphoid malignancy.
Sultan Qaboos University Medical Journal
https://doi.org/10.18295/squmj.2016.16.04.017
Hypesthesia
Plasma Cells
Plasmacytoma
Al-Riyami, Y. M., Bakathir, A., Al-Farsi, K., & Al-Azri, F. (2016). Relapse of multiple myeloma presenting as lower lip numbness. Sultan Qaboos University Medical Journal, 16(4), e500-e503. https://doi.org/10.18295/squmj.2016.16.04.017
Relapse of multiple myeloma presenting as lower lip numbness. / Al-Riyami, Yusra M.; Bakathir, Abdulaziz; Al-Farsi, Khalil; Al-Azri, Faisal.
In: Sultan Qaboos University Medical Journal, Vol. 16, No. 4, 01.11.2016, p. e500-e503.
Al-Riyami, YM, Bakathir, A, Al-Farsi, K & Al-Azri, F 2016, 'Relapse of multiple myeloma presenting as lower lip numbness', Sultan Qaboos University Medical Journal, vol. 16, no. 4, pp. e500-e503. https://doi.org/10.18295/squmj.2016.16.04.017
Al-Riyami YM, Bakathir A, Al-Farsi K, Al-Azri F. Relapse of multiple myeloma presenting as lower lip numbness. Sultan Qaboos University Medical Journal. 2016 Nov 1;16(4):e500-e503. https://doi.org/10.18295/squmj.2016.16.04.017
Al-Riyami, Yusra M. ; Bakathir, Abdulaziz ; Al-Farsi, Khalil ; Al-Azri, Faisal. / Relapse of multiple myeloma presenting as lower lip numbness. In: Sultan Qaboos University Medical Journal. 2016 ; Vol. 16, No. 4. pp. e500-e503.
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title = "Relapse of multiple myeloma presenting as lower lip numbness",
abstract = "Multiple myeloma (MM) is an uncommon malignancy characterised by the proliferation of clonal plasma cells. There are few published reports describing the extramedullary presentation of MM manifesting primarily in the head and neck region. In addition, the occurrence of an isolated relapse of MM in these sites is exceedingly rare. We report a 56-year-old female who presented to the Sultan Qaboos University Hospital, Muscat, Oman, in 2010 with sudden-onset numbness of the lower lip. She had a history of MM in remission following chemotherapy and a bone marrow transplant. Clinical and radiographic examinations were indicative of a possible relapse of MM, which was subsequently confirmed by bone marrow aspiration and histopathological evaluation. This unique case highlights the unusual site of relapse of a haematolymphoid malignancy.",
keywords = "Case report, Head and neck neoplasms, Multiple myeloma, Oman, Plasmacytoma, Relapse",
author = "Al-Riyami, {Yusra M.} and Abdulaziz Bakathir and Khalil Al-Farsi and Faisal Al-Azri",
doi = "10.18295/squmj.2016.16.04.017",
pages = "e500--e503",
journal = "Sultan Qaboos University Medical Journal",
publisher = "Sultan Qaboos University",
T1 - Relapse of multiple myeloma presenting as lower lip numbness
AU - Al-Riyami, Yusra M.
AU - Bakathir, Abdulaziz
AU - Al-Farsi, Khalil
AU - Al-Azri, Faisal
N2 - Multiple myeloma (MM) is an uncommon malignancy characterised by the proliferation of clonal plasma cells. There are few published reports describing the extramedullary presentation of MM manifesting primarily in the head and neck region. In addition, the occurrence of an isolated relapse of MM in these sites is exceedingly rare. We report a 56-year-old female who presented to the Sultan Qaboos University Hospital, Muscat, Oman, in 2010 with sudden-onset numbness of the lower lip. She had a history of MM in remission following chemotherapy and a bone marrow transplant. Clinical and radiographic examinations were indicative of a possible relapse of MM, which was subsequently confirmed by bone marrow aspiration and histopathological evaluation. This unique case highlights the unusual site of relapse of a haematolymphoid malignancy.
AB - Multiple myeloma (MM) is an uncommon malignancy characterised by the proliferation of clonal plasma cells. There are few published reports describing the extramedullary presentation of MM manifesting primarily in the head and neck region. In addition, the occurrence of an isolated relapse of MM in these sites is exceedingly rare. We report a 56-year-old female who presented to the Sultan Qaboos University Hospital, Muscat, Oman, in 2010 with sudden-onset numbness of the lower lip. She had a history of MM in remission following chemotherapy and a bone marrow transplant. Clinical and radiographic examinations were indicative of a possible relapse of MM, which was subsequently confirmed by bone marrow aspiration and histopathological evaluation. This unique case highlights the unusual site of relapse of a haematolymphoid malignancy.
KW - Case report
KW - Head and neck neoplasms
KW - Multiple myeloma
KW - Oman
KW - Plasmacytoma
KW - Relapse
U2 - 10.18295/squmj.2016.16.04.017
DO - 10.18295/squmj.2016.16.04.017
SP - e500-e503
JO - Sultan Qaboos University Medical Journal
JF - Sultan Qaboos University Medical Journal
10.18295/squmj.2016.16.04.017