Dr. Fauci Mobilizing Top Allergists to Investigate if mRNA-based COVID-19 Vaccines Represent Risk to Highly Allergic People or with Mast Cell Disorder
TrialSite Staff April 8, 2021
Do the mRNA-based vaccines for COVID-19 pose any threat to highly allergic individuals or those with Mast Cell Disorder? Apparently, Dr. Anthony Fauci and the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), are significantly enough concerned to organize and sponsor a clinical trial to determine if this group faces increased risk for an immediate, systemic allergic reaction to the Moderna or Pfizer-BioNTech COVID-19 vaccines. A systemic allergic reaction to a vaccine occurs in one or more parts of the body beyond the injection site. If such an allergic reaction occurs in study participants, investigators will assess whether the reactions are more frequent in participants who are highly allergic or have a mast cell disorder than in participants with no allergic history. In addition, investigators will examine the biological mechanism behind the reactions and whether a genetic pattern or other factors can predict who is at most risk. The study involves the Immune Tolerance Network (ITN) investigational site network along with support from a contract research organization (CRO) called Rho Federal Systems Division, Inc. Th...
Source: NIH
Tagged: Allergies, COVID-19, Mast Cell Disorder, Vaccine