Literature References: Prepn: H. Laborit, DE 2229215; idem, US 4169158 (1973, 1979 to Centre Etudes Exper. Clin. Physio-Biologie); C.-G. Wermuth, A. Exinger, Agressologie 13, 285 (1972). Pharmacology: H. Laborit et al., ibid. 291. Metabolism of 14C-minaprine: A. G. Rico et al., J. Pharmacol. 9, 170 (1978). Pharmacokinetics: J. P. Jeanniot et al., ibid. 169. Clinical evaluation: A. Garcia-Maffla, M. H. de Garcia, Pharmatherapeutica 2, 265 (1979). Pharmacological evaluation in depression: K. Bizière et al., Arzneim.-Forsch. 32, 824 (1982). Toxicologic study: A. G. Mazure et al., Agressologie 13, 319 (1972).
Properties: Fine buff-colored needles from isopropanol, mp 122°. Insol in water. Slightly sol in cold ethanol, sol in hot ethanol, chloroform.
Properties: Crystals from abs ethanol, mp 182°.