METABRAIN is a dynamic team of specialists in metabolic diseases integrating capabilities in medicinal chemistry, biology, and pharmacology.
Our experience in drug discovery and our expertise in metabolic disorders enable us to complement our technical capacities with high-value consulting and study design assistance.
We offer personalized integrated or stand alone research services covering medicinal chemistry, in vitro biology and in vivo – ex vivo pharmacology. Our client-driven activity aims at increasing the value of our partners' portfolio by focusing on the endpoints that matter most. The full potential of our platforms is unleashed when our chemist, biologist and pharmacologist work together on integrated drug discovery programs. Our know-how is also applicable to nutraceutic development.
Our scientists can help you take your hit series to lead candidates with improved potency & PK profile through their medicinal chemistry know-how based on a balance of SAR, molecular modeling, pharmacophore models and physiochemical properties analysis.
Our labs have the synthetic capacities to produce up to 100g of purified candidate through a wide range of synthetic routes and an analytical platform for compound analysis & structural determination. Compounds registration and storage are handled by our dedicated logistic unit.
Our platforms have a wide range of metabolic profiling capacities available to evaluate either the systemic action of compounds or understand their molecular mechanisms of action.
In addition we develop customized assays in order to complete characterization if necessary.