Ninety-six percent of the top 50 healthcare companies in the world are using engineering simulation and computer-based models routinely. Leading medical device companies are realizing that a large fraction of their engineering force should be using simulation regularly. The FDA and other regulatory authorities encourage the adoption of computer models and simulation (CM&S) — also known as the "in silico" approach — to accelerate the approval process. But many companies are still unsure of how best to adopt and deploy this technology. This monthly webcast series shares the knowledge and experience of ANSYS experts and our partners to guide you in the strategic adoption of engineering simulation.
Attend this webinar and learn how DEM and CFD simulations can be used to predict tasks like tablet mixing in a coating operation. Find out how to improve and develop high-efficiency pharmaceutical equipment design.
The predictive modeling of cardiac mechanics to accurately reproduce the heart's functionality and response to external disturbances remains a challenging task. The need to assess multiple physical domains — structural mechanics, fluid dynamics and electrophysiology — places high demands on numerical solution strategies.
We will present a high-resolution, 3-D, nonlinear finite element model of patient-specific heart geometries and function. The model includes an active material law prescribing the ventricular contraction along a generic muscle fiber orientation and a passive component that captures the highly anisotropic nonlinear behavior of the myocardium.
By coupling the structural model with the ventricular blood compartments, which act as zero-dimensional fluid representations of the cardiovascular system, we can model venous return by assuring conservation of volume within the closed loop circulatory system. The resulting monolithic, multifield system of equations, provides a physiologically meaningful solution of heart contraction mechanics for in silico modeling of medical device and novel disease treatment.
View this webinar to learn more about the role of CM&S as a tool in generating evidence for MR device safety. The speaker will also cover important topics such as worst-case selection methodology and computational model verification, validation and uncertainty quantification.
Computational modeling is recognized by both industry and regulatory agencies as an alternative to physical testing, but it has historically been used in silos with minimal collaboration between various design disciplines and engineering departments. To address the needs of today's product development teams, ANSYS has developed a multi-domain, system simulation and digital prototyping platform that enables multi-specialty teams with diverse engineering backgrounds to work in unison to achieve a deep understanding of integrated product behavior.
Attend this webinar to learn about a systems simulation solution of a wearable insulin pump that illustrates the complexities of developing these multi-disciplinary systems. The model includes evaluation of various physical components, control algorithms, display interfaces and power electronics. In addition to the presentation, a live demo will show how various components can be combined to model the drug delivery sub-system using a hardware-in-the-loop approach.
Computational fluid dynamics has long been a resource for understanding how geometry and physics influence bodily function. But CFD is only part of the equation. Human physiology is determined by biological and physical factors that influence, and are influenced by, the objects of CFD models; combining these two domains is critical for increased validity of simulations. Combining HumMod, a lumped parameter model of human physiology, with advanced 3-D CFD tools like ANSYS Fluent will enable researchers, clinicians and healthcare companies to better understand proposed physiological mechanisms and interactions, allowing higher level properties of complex physiological systems to emerge.
This webinar illustrates unsteady breathing in Fluent with boundary conditions imported from HumMod as an example of the work in progress.
This webinar provides a compelling overview of how predictive models are used at various stages of development and manufacturing in the biopharmaceutical industry. Case studies covering a wide range of the biologic product chain from drug substance to drug product and devices are presented, to show how modeling contributes to the scientific advancement, strategic objectives, and bottom line of our technical operations at Biogen. While our main focus is on mainstream applications of CFD modeling in the biopharmaceutical industry, non-traditional uses of CFD and other first-principles modeling techniques will also be presented here. Through this presentation, we intend to provide inspiring perspectives on the value of predictive models and advocate their increased adoption in the Biopharmaceutical industry.
For more than 20 years, the orthopedic sector has widely adopted engineering simulation and finite element analysis to accelerate the development of new implants. Today, most hip prostheses, knee joints and spinal implants are optimized through computer modeling. During the last few years leading orthopedic companies have developed an in silico testing approach, which enables them to test new prototypes on a relatively large population of virtual patients.
Attend this webinar to learn how ANSYS simulation solutions can give you a more detailed understanding of all articulations including the shoulder, elbow, wrist and ankle. For patient-specific implants to become standard, including synovial fluid and electromagnetic interaction modeling are the obvious next steps. Learn about a workflow that takes you from patient to simulation, while including fluid–structure interaction behavior in your shoulder model.
Recent reports by the EU Council and U.S. Congress encourage a number of innovative approaches to streamline the regulatory approval process for approving medical devices, including the large-scale adoption of computer-based models. The extensive use of simulation in clinical research will lead to the definition of Good Simulation Practice (GSP) standard guidelines for computer modeling and testing as Good Clinical Practices (GCP) are used in traditional clinical trials.
Attend this webinar to learn how the web-based platform, InSilicoTrials.com, will provide healthcare companies with an easy-to-use tool to perform computational testing on their devices during the development and validation process.
Attend this webinar to discover how the ANSYS model-based embedded software development and simulation environment — with a built-in (and safety certified) automatic code generator — significantly accelerates the pace of embedded software development projects, including complex user interfaces and control software. Learn how the use of familiar ANSYS tools can help medical engineers make mobile health smarter and more effective.
A key challenge for medical device designers is to understand and optimize the communication between the device and the receiver. Pioneering companies like Cambridge Consultants were early adopters of engineering simulation to model the behavior of medical devices and their communication components, together with the surrounding environment – and particularly 'through-body' communication. In this webinar, we will discuss the growing importance of connectivity and the necessity of using computer-based modeling to enable this critical technology. Cambridge Consultants will also present a case study that highlights the use of computer modeling to quantify the impact of different body morphologies on implant radio performance. An understanding of these coupled with use case and end user morphology will define if the radio performance is incredibly successful or marginally adequate.
Attend this webinar to learn how Creare used ANSYS Fluent for aerodynamic design and nasal deposition modeling in support of the DPI device development. Discover how analyses performed with ANSYS Mechanical were used to design the piezoelectric actuator, a key component in the aerosol generation process for the InVax device.
In silico medicine enables doctors to customize a treatment based on simulations run on models of the patient's own anatomical geometry, which can be obtained from various scanning methods. Such patient-specific treatments understandably achieve better clinical results. ANSYS 17.0, with hundreds of enhancements across all physics, could be a significant catalyst in the discovery of many more devices and applications in this expanding medical sector.
Attend this webinar to learn how advances in ANSYS 17.0 could boost medical innovation by a factor of ten (10x) by accelerating computation time, increasing adoption of simulation by non-expert users, and multiplying the reliability and safety of new medical devices. Discover 10 reasons why enhancements to ANSYS fluid, mechanical, electronic and systems simulation software can benefit all healthcare sectors — cardiovascular, orthopedic, pharmaceutical, hospital and medical supplies, diagnosis — through increased use of in silico medicine.
Attend this webinar to learn how medical device engineers are designing IoT devices with increasing requirements for thermal and power management, ruggedness, miniaturization, number of sensors, wireless capabilities, MR compliance, etc. Discover how ANSYS simulation solutions have the potential to increase both the effectiveness and affordability of healthcare by expanding the medical IoT.
Attend this webinar to learn how two entrepreneurial clinical groups have adapted ANSYS software for new medical treatments. Discover how BRACESIM, developed by Rodin 4d, assists orthotists in customizing braces to treat scoliosis, decreasing the number of physical iterations needed to get the right brace, while reducing brace weight and increasing patient satisfaction. And find out how WOST, created by Sim & Cure, provides crucial assistance to neurosurgeons treating cerebral aneurysms by performing patient-specific stent development in less than 15 seconds.
What are Healthcare Thought Leaders Foreseeing for 2016?
Mixing tank design scale-up has traditionally required a large number of CAE experts. While engineering simulation has strongly reduced development costs and time to market, using CAE experts made this task increasingly cost-prohibitive, until now. Join us for this webinar to discover how the ANSYS India team, working with some pharma and biotech leaders, developed a simplified, customized interface for ANSYS Fluent that enables non-expert users to set up advanced mixing tank modeling. Learn how this innovative mixing tank template allows new users to gain simulation experience, while freeing up CAE experts for more advanced tasks.
Quality by Design (QbD) is a concept encouraged by the FDA that integrates quality into a product through understanding of both the product and the process by which it was manufactured. This webinar will provide an introduction to the application of CFD tools in the biopharmaceutical industry and will continue with two case studies. Both case studies will focus on designing production-scale bioreactors using CFD. The first will summarize a DOE-based design of bioreactor to optimize gas sparging, and the second will describe a methodology to engineer and design a production-scale bioreactor that reduces the risk of scaling-up a microcarrier-based mammalian cell culture process.
It's a challenge to model the human body's interaction with electromagnetic, structural, thermal and acoustic stimuli. One large limitation is the availability of anatomically accurate and numerically efficient computational phantoms. In this study, we disclose a new computational phantom designed specfically for ANSYS HFSS and ANSYS Maxwell 3-D.
AirPROM (Airway Disease Predicting Outcomes through Patient Specific Computational Modeling) is a five year European project; it aims to produce computer and physical models of the whole airway system for people with asthma and chronic obstructive pulmonary disease. Using a model of a patient's own airway system and simulating its functionality through software could help to improve diagnoses, treatments and outcomes for people suffering from these conditions.
Customizing surgical treatments and medical devices by incorporating patient-specific geometries in simulations opens the door to better, more successful healthcare. Patient-specific geometries typically come from medical scans — MRI, PET, CT — and they often require preprocessing for accurate simulations. In this webinar, we will discuss how ANSYS SpaceClaim provides the medical community with new techniques to make editing of patient-specific geometries faster and easier, leading to better treatment planning and more successful outcomes.
By combining High Resolution CT Thorax (HRCT) imaging and flow simulation (CFD), FLUIDDA has developed Functional Respiratory Imaging (FRI). FRI provides local information about the lung structure (using HRCT measurement) and function (using ANSYS CFD). This combination of imaging technology and engineering simulation was applied to more than 1,500 patients suffering from various pathologies, including asthma, COPD, cystic fibrosis, chronic sinusitis, idiopathic pulmonary fibrosis and others. For these patients, FRI provides a more detailed picture of how their treatment is working, and guides physicians to choose the optimal next steps for improved outcomes.
Continuum FE models of bones and bone-implant configurations have become a standard tool to estimate bone strength. These models are usually based on clinical CT scans. In virtually all of these models, material properties assigned to the bone elements are chosen as isotropic with a stiffness based only on the density distribution. It has been shown, however, that trabecular bone can be highly anisotropic and it shows elastic plastic damage mechanical behaviour with softening.