Precise regulation of signal transduction is required to control normal biological processes. However, deregulated cellular signal transduction pathways have been related to a number of disorders, ranging from relatively non life-threatening diseases to extremely virulent diseases such as cancer as a consequence of loss of growth control and resistance to apoptosis. In particular targeting of protein kinases is a promising field in the future treatments of cancer since they are able to derail normal biological responses and drive a cell toward neoplastic transformation. Research in our group is focused on a wide range of cellular signal transduction pathways initiated by interaction of host cells with pathogens like Helicobacter pylori, Campylobacter jejuni, Shigella flexneri, etc.
We currently offer exciting projects for Master students!
This research group is a member of the international "PhD program ICA" of the University of Salzburg and the FWF and a member of the priority program "Allergy-Cancer-BioNano Research Centre" of the University of Salzburg.