Mouse anti Dog C-reactive protein, clone cCRP3, specifically recognizes canine C-reactive protein (CRP), a calcium-binding acute phase reactant belonging to the pentraxin family which is secreted into the plasma by the liver in response to cytokine stimulation.
Canine CRP is similar in structure to human CRP, however canine CRP differs in that two of the five subunits that make up CRP in dogs are glycosylated while normally none of the subunits making up human CRP are. As clone cCRP3 is specifically raised against dog, this antibody has an advantage over other antibodies raised against human that show cross reactivity with dog, as these cross reactive antibodies may not recognize the glycosylated subunits.
Clone cCRP3 recognizes a linear epitope.