Create and add a configuration file similar to below.
Lucinq on Sitecore 7 utilises the default indexes, I generally recommend duplicating the default Web and Master index configurations that come with Sitecore and replacing the name.
Lucinq also comes with a fix to the template structure to allow querying based upon base templates.
You can either rebuild the index using the Index Viewer Module (which is my preferred method on versions of Sitecore previous to 7, or use the control panel or developer ribbon. Your index should be called 'lucinq_index' if you have used the configuration above for Sitecore 6.x. If you are using Sitecore 7.x then you can use the default configured indexes.
Ok, so now you have installed Lucinq, you can now go ahead and create a search.