Evaluate the collective function of references cited together in a given text segment.
Classify their combined role into one of the following categories: 'method', 'background', or 'result'.

Text:The high concentration of Ca in the cytosol activates several proteases and other proteins that lead to dysfunction and destruction of organelle membranes and corruption of normal metabolism [21, 23, 33, 64, 100, 101, 107–115].
Category: