Similar to OP9/L cells, the primary ECs in KOBA-bearing mice showed increased CD34 expression, which is characteristic of new angiogenesis in human CML [35], implying that these ECs are derived in part fromMSCs via transdifferentiation [36] [37].
Sample text:```This study supports the theory of a tumor origin from multipotential progenitor cells.(14) Reports of the Ki67 labeling index have demonstrated great variety.```
Sample intent: result
Sample text:```Interestingly, MHC I and ERAP1 were coordinately expressed in normal and, to a lesser extent, neoplastic cells and tumor lesions (13, 14).```
Sample intent: method



Sample text:```Our results further confirm previous findings on the differential regulatory mechanisms for Hoxa3 and Hoxb3 expression in r5 and r6 by kreisler (Manzanares et al., 1997, 1999a,b, 2001).```
Sample intent: result



Sample text:```In addition, consistent with the result of our preclinical study, recent clinical study showed that alectinib was also highly active against ALK-positive NSCLC patients after treatment with crizotinib [21].```
Sample intent: result



Sample text:```, 2009), are most abundant on endosomes undergoing the early-to-late transition (Rojas et al., 2008; Cullen and Korswagen, 2012; van Weering et al., 2012).```
Sample intent: method



Sample text:```Cell-tracing experiments in chicken (Jaffredo et al., 2000; Jaffredo et al., 1998) and mouse (Chen et al., 2009; de Bruijn et al., 2002; Sugiyama et al., 2003; Zovein et al., 2008) species indicate that IAHCs derive from hemogenic ECs through an Endothelial-to-Hematopoietic Transition (EHT).```
Sample intent: method
Sample text:```Unlabeled DNA substrates containing consensus 12-RSS, 23-RSS, Hox11 or non-specific DNA sequences (DAR81/82) were prepared from oligonucleotides described previously [11,24].```
Sample intent: background



Sample text:```Interestingly, MHC I and ERAP1 were coordinately expressed in normal and, to a lesser extent, neoplastic cells and tumor lesions (13, 14).```
Sample intent: method



Sample text:```Intriguingly, using MPRs-deficient MEF cells, mouse and human CLN5 have been shown to reach lysosomes in an MPRindependent manner [12].```
Sample intent: background



Sample text:```In line with our results, several previous studies demonstrated the anti-proliferative effect of PPARs agonists in several cell types [11-15].```
Sample intent: result



Sample text:```Cell-tracing experiments in chicken (Jaffredo et al., 2000; Jaffredo et al., 1998) and mouse (Chen et al., 2009; de Bruijn et al., 2002; Sugiyama et al., 2003; Zovein et al., 2008) species indicate that IAHCs derive from hemogenic ECs through an Endothelial-to-Hematopoietic Transition (EHT).```
Sample intent: method



Sample text:```, 2009), are most abundant on endosomes undergoing the early-to-late transition (Rojas et al., 2008; Cullen and Korswagen, 2012; van Weering et al., 2012).```
Sample intent: method



Sample text:```In addition, consistent with the result of our preclinical study, recent clinical study showed that alectinib was also highly active against ALK-positive NSCLC patients after treatment with crizotinib [21].```
Sample intent: result



Sample text:```This study supports the theory of a tumor origin from multipotential progenitor cells.(14) Reports of the Ki67 labeling index have demonstrated great variety.```
Sample intent: result



Sample text:```Lee et al. (2001) Human lung squamous cell carcinoma (CH27), human lung nonsmall cell carcinoma (H460) CH27 and H460 cells were treated with aloeemodin or emodin.```
Sample intent: method



Sample text:```Isolation of cardiomyocytes by standard enzymatic techniques and patch-clamp recordings were performed as described previously [42].```
Sample intent: background