hydrogen-bonded cluster of charged amino acids, called the charge triad, which is important for apoptosis inhibition.(13,14,22) To analyze whether the charge triads play
Sample text:```Because previous studies indicated that hexapeptides bind the junction core (29, 32), we tested two junctions, one with an AT-rich core and the other with a GC-rich core (Fig.```
Sample intent: result
Sample text:```This study supports the theory of a tumor origin from multipotential progenitor cells.(14) Reports of the Ki67 labeling index have demonstrated great variety.```
Sample intent: result



Sample text:```Following the experimental design proposed in Yannakakis and Hallam (2007c) and Yannakakis et al. (2008) for effectively capturing the level of entertainment, the test-bed game under investigation is played in variants.```
Sample intent: background



Sample text:```To fulfill these functions, Hsp90 interacts with its cofactors and cochaperones including Hsp70, immunophilins, and p23, to form the Hsp90based chaperone complex.(1,2) Natural compounds such as geldanamycin and radicicol bind the ATP-binding pocket of Hsp90, and disrupt its chaperone function.```
Sample intent: method



Sample text:```U-box domain does not depend on zinc binding to keep its stability, but have evolved instead networks of hydrogen bonds and salt bridges formed by the corresponding residues at metal ligand positions (Hatakeyama et al., 2001; Nordquist et al., 2010; Wiborg et al., 2008).```
Sample intent: method



Sample text:```c-Jun-N-Terminal inhibitory kinase JIK and TRAF2 to the stimulated ER stress sensor IRE-1, where TRAF2 can activate ASK-1, an upstream activating kinase of JNK (2) activation of caspase 12, which is released from its```
Sample intent: method
Sample text:```A number of studies have been published recently, which analyze the location, orientation, and identity ofmacromolecular complexes, based on the outcome of template-matching (Brandt et al., 2009; Ortiz et al., 2010).```
Sample intent: method



Sample text:```We screened for potential TF binding sites using STAMP [59], with the motifs’ position weight matrices (PWMs) retrieved from the TRANSFAC database [60].```
Sample intent: background



Sample text:```Intriguingly, using MPRs-deficient MEF cells, mouse and human CLN5 have been shown to reach lysosomes in an MPRindependent manner [12].```
Sample intent: background



Sample text:```To fulfill these functions, Hsp90 interacts with its cofactors and cochaperones including Hsp70, immunophilins, and p23, to form the Hsp90based chaperone complex.(1,2) Natural compounds such as geldanamycin and radicicol bind the ATP-binding pocket of Hsp90, and disrupt its chaperone function.```
Sample intent: method



Sample text:```This study supports the theory of a tumor origin from multipotential progenitor cells.(14) Reports of the Ki67 labeling index have demonstrated great variety.```
Sample intent: result



Sample text:```Following the experimental design proposed in Yannakakis and Hallam (2007c) and Yannakakis et al. (2008) for effectively capturing the level of entertainment, the test-bed game under investigation is played in variants.```
Sample intent: background



Sample text:```For experiments measuring the effect of Sch-28080 and ouabain on pHi recovery in ICs, only basolateral Cl removal was used to differentiate IC types (15, 17).```
Sample intent: background



Sample text:```Our results show that after 4 h of thiotepa treatment, the level of expression of anti-apoptotic Bcl-2 was not changed; this confirms the results of a previous study [25].```
Sample intent: result



Sample text:```They play an important
role in stabilizing coordination geometries, adjusting ligand donor strengths, and mediating proton transfer reactions (Span et al. 2017; Holm et al. 1996; Makris et al. 2007).```
Sample intent: method



Sample text:```U-box domain does not depend on zinc binding to keep its stability, but have evolved instead networks of hydrogen bonds and salt bridges formed by the corresponding residues at metal ligand positions (Hatakeyama et al., 2001; Nordquist et al., 2010; Wiborg et al., 2008).```
Sample intent: method