Therefore to avoid missing potential true associations as well as avoid keeping possibly false associations, we considered two sequential association studies to
identify SNPs associated with SUA, TG, or HDL. SNPs with an adjusted p-value#0.005 were considered significant in the initial discovery process in PEAR.
Sample text:``` The GRS was then calculated by summing across all SNPs (the GRS could theoretically range from 0 to 58).```
Sample intent: background
Sample text:```We screened for potential TF binding sites using STAMP [59], with the motifs’ position weight matrices (PWMs) retrieved from the TRANSFAC database [60].```
Sample intent: background



Sample text:```This is interesting in relation to the result from our previous CGH study (comparing the number of significantly hybridizing probes on the microarray) that showed high sequence divergence on the Z chromosome between the common whitethroat and the zebra finch [62]; and such patterns are also found in other species [48,51,69].```
Sample intent: result



Sample text:```Because previous studies indicated that hexapeptides bind the junction core (29, 32), we tested two junctions, one with an AT-rich core and the other with a GC-rich core (Fig.```
Sample intent: result



Sample text:```Classification of Genetic Variants All genetic variants in our cohort and those reported in the manuscripts uncovered by the literature search were reassessed and classified according to the current guidelines of the American College of Medical Genetics.13 For this evaluation, we used MAF data derived from the Exome Aggregation Consortium and the Exome Variant Server.```
Sample intent: background



Sample text:```Similarly, a synergistic effect of sequence differences at the resistin locus on obesity and risk of type II diabetes has been observed (Ma et al, 2002).```
Sample intent: method
Sample text:```Previous studies have shown that sialome genes were subject to strong ancient selective pressures that have resulted in species-specific adaptations (Varki 2001; Angata et al. 2004; Altheide et al. 2006; Varki & Gagneux 2009), suggesting that they likely evolved in response to ancient pathogens The function of sialome genes, i.```
Sample intent: result



Sample text:```58% of ethnically matched control chromosomes.(8) Examination of the dbSNP shows that the frequency of the rs6746030 polymorphism in control samples is ethnicity dependent: American Caucasians of European descent, 12.```
Sample intent: method



Sample text:```Consistent with our results, there was no significant association of 25(OH)D and mortality in a 3-year follow-up study of 230 Chinese patients with a median peritoneal dialysis duration of 26 months [7].```
Sample intent: result



Sample text:```Our genealogy, based on many alleles but only the first exon of bindin, is not entirely consistent with that of McCartney and Lessios (2004), based on fewer alleles but incorporating the entire molecule.```
Sample intent: result



Sample text:```Quantitative geneticists have documented numerous cases of such interactions (Stuber et al. 1992; Ragot et al. 1995; Cockerham and Zeng 1996; Melchinger et al. 1998).```
Sample intent: method



Sample text:```Classification of Genetic Variants All genetic variants in our cohort and those reported in the manuscripts uncovered by the literature search were reassessed and classified according to the current guidelines of the American College of Medical Genetics.13 For this evaluation, we used MAF data derived from the Exome Aggregation Consortium and the Exome Variant Server.```
Sample intent: background



Sample text:``` The GRS was then calculated by summing across all SNPs (the GRS could theoretically range from 0 to 58).```
Sample intent: background



Sample text:```Similarly, a synergistic effect of sequence differences at the resistin locus on obesity and risk of type II diabetes has been observed (Ma et al, 2002).```
Sample intent: method



Sample text:```The sgl gene has been shown to be expressed differentially during development (Binari et al. 1997; Haerry et al. 1997).```
Sample intent: method



Sample text:```This is interesting in relation to the result from our previous CGH study (comparing the number of significantly hybridizing probes on the microarray) that showed high sequence divergence on the Z chromosome between the common whitethroat and the zebra finch [62]; and such patterns are also found in other species [48,51,69].```
Sample intent: result