A relevant example of this modulatory function is the Lysine Specific Demethylase 1A (KDM1A/LSD1) that was recently described as corepressor and coactivator for the androgen receptor (AR) in prostate cancer (84).
Sample text:```Unlabeled DNA substrates containing consensus 12-RSS, 23-RSS, Hox11 or non-specific DNA sequences (DAR81/82) were prepared from oligonucleotides described previously [11,24].```
Sample intent: background
Sample text:```hemicholinium-3, a depletor of endogenous acetylcholine (Parikh and Sarter, 2006); (ii) by enhancing cholinergic tone with AF-DX384, a selective M2/M4 autoreceptor antagonist, that blocks the self-inhibitory mechanism by which acetylcholine regulates its own release and (iii) by selectively blocking M1 muscarinic receptors, key modulators of both LTD and LTP (Calabresi et al., 2000; Wang et al., 2006; Bonsi et al., 2008).```
Sample intent: method



Sample text:```They play an important
role in stabilizing coordination geometries, adjusting ligand donor strengths, and mediating proton transfer reactions (Span et al. 2017; Holm et al. 1996; Makris et al. 2007).```
Sample intent: method



Sample text:```In our previous study, we found that RAG-mediated nicking and cleavage of oligonucleotide substrates containing cRSSs identified from lymphoid malignancies were either unchanged or slightly reduced in the presence of HMGB1 for most cRSSs tested (including LMO2, TAL1, Hox11, SIL, SCL), except Ttg-1 [24].```
Sample intent: method



Sample text:```Two days after transfection, cells were harvested and D2 activity was measured in lysates using HPLC, as described previously (20).```
Sample intent: background



Sample text:```Unlabeled DNA substrates containing consensus 12-RSS, 23-RSS, Hox11 or non-specific DNA sequences (DAR81/82) were prepared from oligonucleotides described previously [11,24].```
Sample intent: background
Sample text:```hemicholinium-3, a depletor of endogenous acetylcholine (Parikh and Sarter, 2006); (ii) by enhancing cholinergic tone with AF-DX384, a selective M2/M4 autoreceptor antagonist, that blocks the self-inhibitory mechanism by which acetylcholine regulates its own release and (iii) by selectively blocking M1 muscarinic receptors, key modulators of both LTD and LTP (Calabresi et al., 2000; Wang et al., 2006; Bonsi et al., 2008).```
Sample intent: method



Sample text:```Previous studies have shown that sialome genes were subject to strong ancient selective pressures that have resulted in species-specific adaptations (Varki 2001; Angata et al. 2004; Altheide et al. 2006; Varki & Gagneux 2009), suggesting that they likely evolved in response to ancient pathogens The function of sialome genes, i.```
Sample intent: result



Sample text:```Two days after transfection, cells were harvested and D2 activity was measured in lysates using HPLC, as described previously (20).```
Sample intent: background



Sample text:```This study supports the theory of a tumor origin from multipotential progenitor cells.(14) Reports of the Ki67 labeling index have demonstrated great variety.```
Sample intent: result



Sample text:```Several studies have shown that a major function of PP2A is downregulation of the Ras/MAP kinase pathway (2, 3, 22, 30, 50, 51, 53).```
Sample intent: method



Sample text:```The PCR product was digested with AgeI/NotI and ligated between the G and the L gene (similar to Roberts et al., 1999) into the vectors pVSVCT-1 and pVSVCT-9 (Schnell et al., 1998), which had been digested with XmaI/NotI.```
Sample intent: background



Sample text:```germination stimulatory activity by germination bioassays with Striga hermonthica as previously described by Jamil et al. (2010).```
Sample intent: background



Sample text:```In line with our results, several previous studies demonstrated the anti-proliferative effect of PPARs agonists in several cell types [11-15].```
Sample intent: result



Sample text:```They play an important
role in stabilizing coordination geometries, adjusting ligand donor strengths, and mediating proton transfer reactions (Span et al. 2017; Holm et al. 1996; Makris et al. 2007).```
Sample intent: method



Sample text:```Intriguingly, using MPRs-deficient MEF cells, mouse and human CLN5 have been shown to reach lysosomes in an MPRindependent manner [12].```
Sample intent: background