1 to 10 nM ouabain prevented cell death and promoted cell growth, whereas concentration > 1 μM prevented cell proliferation associated with extensive inhibition of Na/K-ATPase enzyme activity [37].
Sample text:```The ¬¨¬µ-opioid receptor agonist morphine also induced inhibitory effects in both assays, in accordance with previous reports describing the opiate-mediated inhibition of the BSL evoked in mice by excitatory amino acids and neurokinins (Aanonsen et al. 1987; Takahasi et al. 1987; Wilcox 1988).```
Sample intent: result
Sample text:```Isolation of cardiomyocytes by standard enzymatic techniques and patch-clamp recordings were performed as described previously [42].```
Sample intent: background



Sample text:```Previous studies revealed that acylcarnitines were elevated early after APAP treatment and that their elevation was indicative of mitochondrial damage and dysfunction.(15,19) In the present study these observations were confirmed, as palmitoylcarnitine was elevated by toxic doses of APAP and maintained at normal levels (compared with untreated controls) by Wy-14,643 pretreatment.```
Sample intent: result



Sample text:```The inter-relationships between K1, K1O and anticoagulants in dogs and humans have been previously investigated [25, 26].```
Sample intent: background



Sample text:```For experiments measuring the effect of Sch-28080 and ouabain on pHi recovery in ICs, only basolateral Cl removal was used to differentiate IC types (15, 17).```
Sample intent: background



Sample text:```They demonstrated by in vitro and ex vivo studies that ATP1A1 mutants showed loss of pump activity and strongly reduced affinity for potassium, causing inappropriate depolarization of the cells (Beuschlein et al. 2013).```
Sample intent: method
Sample text:```In line with our results, several previous studies demonstrated the anti-proliferative effect of PPARs agonists in several cell types [11-15].```
Sample intent: result



Sample text:```germination stimulatory activity by germination bioassays with Striga hermonthica as previously described by Jamil et al. (2010).```
Sample intent: background



Sample text:```Basal ATP concentrations in the bulk medium of unstimulated CFs are low, but the concentrations of released nucleotides near the cell surface may be sufficient to activate adjacent P2Y receptors and contribute to basal signaling (48, 49).```
Sample intent: method



Sample text:```Our results show that after 4 h of thiotepa treatment, the level of expression of anti-apoptotic Bcl-2 was not changed; this confirms the results of a previous study [25].```
Sample intent: result



Sample text:```Secondly, this effect was shown to be selectively due to CCK2 activation (Ladurelle et al. 1997) through mechanisms involving δ-opioid (Daugé et al. 1999) and D1-dopamine receptors (Ladurelle et al. 1993) that could be blocked by the selective antagonists naltrindole (a δ antagonist), and SCH23,390.```
Sample intent: method



Sample text:```For experiments measuring the effect of Sch-28080 and ouabain on pHi recovery in ICs, only basolateral Cl removal was used to differentiate IC types (15, 17).```
Sample intent: background



Sample text:```When MgTx was applied to the rare cells subsequently shown to express only TTX-sensitive Na current (A-type neurons) (Stansfeld and Wallis 1985; Schild and Kunze 1997; Li and Schild 2007b), there was no change in the duration of the action potential measured at 0 mV (0.74 0.09 vs. 0.76 0.1 ms, n 3,…```
Sample intent: method



Sample text:```They demonstrated by in vitro and ex vivo studies that ATP1A1 mutants showed loss of pump activity and strongly reduced affinity for potassium, causing inappropriate depolarization of the cells (Beuschlein et al. 2013).```
Sample intent: method



Sample text:```Effects of CACC inhibitors were analyzed by the following four-parameter logistic function: y min (max min)/[1 (x/IC50) Hill slope], where min and max are the bottom and top of the curve, respectively, IC50 is the concentration of half inhibition of block, and the Hill slope is a reflection of the steepness of the curve.```
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Sample text:```Further studies are still needed to exclude other purines such as ATP and related nucleotides, due to their significant release from bladder urothelium [8,9], and since ATP in some species can inhibit or relax the bladder [33–35].```
Sample intent: method