Some studies suggest that tumor cells can survive and proliferate in bone tissues by acquiring a bone-cell phenotype and osteoblastic features termed osteomimicry [36, 47].
Sample text:```Intriguingly, using MPRs-deficient MEF cells, mouse and human CLN5 have been shown to reach lysosomes in an MPRindependent manner [12].```
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Sample text:```The electrode locations, acquired with a post-implantation CT were projected on the T1weighted individual anatomy scan (Hermes et al. 2010).```
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Sample text:```This study supports the theory of a tumor origin from multipotential progenitor cells.(14) Reports of the Ki67 labeling index have demonstrated great variety.```
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Sample text:```Interestingly, MHC I and ERAP1 were coordinately expressed in normal and, to a lesser extent, neoplastic cells and tumor lesions (13, 14).```
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Sample text:```Intriguingly, using MPRs-deficient MEF cells, mouse and human CLN5 have been shown to reach lysosomes in an MPRindependent manner [12].```
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Sample text:```ly), which have been originally identified as molecules activated by growth factor-stimulation of fibroblusts, are key kinases in the intracellular signal transduction pathways (1-6).```
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Sample text:```Isolation of cardiomyocytes by standard enzymatic techniques and patch-clamp recordings were performed as described previously [42].```
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Sample text:```This study supports the theory of a tumor origin from multipotential progenitor cells.(14) Reports of the Ki67 labeling index have demonstrated great variety.```
Sample intent: result



Sample text:```Intriguingly, using MPRs-deficient MEF cells, mouse and human CLN5 have been shown to reach lysosomes in an MPRindependent manner [12].```
Sample intent: background



Sample text:```Endothelial cell cultures and capillary tubeswere generated as previously described (5, 11).```
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Sample text:```In addition, consistent with the result of our preclinical study, recent clinical study showed that alectinib was also highly active against ALK-positive NSCLC patients after treatment with crizotinib [21].```
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Sample text:```These are in keeping with earlier studies on the steadystate response (2, 5, 8), step-function response, (3, 5, 6, 14) and sinusoidal response ( 14) of the various vascular beds.```
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Sample text:```Overexpression of miR-218 inhibits cancer cell proliferation, migration and invasion [24, 26, 27], and promotes colon cancer cell apoptosis [28].```
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Sample text:```In line with our results, several previous studies demonstrated the anti-proliferative effect of PPARs agonists in several cell types [11-15].```
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Sample text:```Interestingly, MHC I and ERAP1 were coordinately expressed in normal and, to a lesser extent, neoplastic cells and tumor lesions (13, 14).```
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Sample text:```Our results show that after 4 h of thiotepa treatment, the level of expression of anti-apoptotic Bcl-2 was not changed; this confirms the results of a previous study [25].```
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