IFNc and LPS synergize to induce nitrite production in primary murine microglia
Numerous reports have established that IFNc alone can induce iNOS in myeloid cells, but these experiments often used high, pharmacological concentrations ( 100 ng/ml) of IFNc (Alberati-Giani et al., 1997).
Sample text:```Aside from the effects on Th1 cells, IL-27 has recently reported that played a regulatory role in limiting excessive inflammation during infection with Toxoplasma gondii by modulating the development of Th17 cells (20, 21).```
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Sample text:```Dead individuals were removed, surface sterilized with 5.2% sodium hypochlorite, rinsed twice with sterile water, and plated on potato dextrose agar to confirm that mortality was due to infection by M. anisopliae (Rosengaus et al. 1998).```
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Sample text:```Laboratory parameters considered in this study were those already found significantly different between early PMF and WHO-ET: Hb (g/dL), WBC (3109/L), PLT (3109/L), and LDH (mU/mL).```
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Sample text:```Induction of C1qa in the CNS promotes synapse elimination and synaptic dysfunction during development, neurodegenerative diseases such as glaucoma and AD, and aging [29,30,31,32,74].```
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Sample text:```germination stimulatory activity by germination bioassays with Striga hermonthica as previously described by Jamil et al. (2010).```
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Sample text:```Aside from the effects on Th1 cells, IL-27 has recently reported that played a regulatory role in limiting excessive inflammation during infection with Toxoplasma gondii by modulating the development of Th17 cells (20, 21).```
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Sample text:```Although NO can react directly with O2 - to form peroxynitrite (Lipton et al. 1993), the production of O2 - by wounding was from the leaves incubated with water.```
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Sample text:```Intriguingly, using MPRs-deficient MEF cells, mouse and human CLN5 have been shown to reach lysosomes in an MPRindependent manner [12].```
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Sample text:```Two days after transfection, cells were harvested and D2 activity was measured in lysates using HPLC, as described previously (20).```
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Sample text:```Basal ATP concentrations in the bulk medium of unstimulated CFs are low, but the concentrations of released nucleotides near the cell surface may be sufficient to activate adjacent P2Y receptors and contribute to basal signaling (48, 49).```
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Sample text:```Aside from the effects on Th1 cells, IL-27 has recently reported that played a regulatory role in limiting excessive inflammation during infection with Toxoplasma gondii by modulating the development of Th17 cells (20, 21).```
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Sample text:```Our results show that after 4 h of thiotepa treatment, the level of expression of anti-apoptotic Bcl-2 was not changed; this confirms the results of a previous study [25].```
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Sample text:```The ¬¨¬µ-opioid receptor agonist morphine also induced inhibitory effects in both assays, in accordance with previous reports describing the opiate-mediated inhibition of the BSL evoked in mice by excitatory amino acids and neurokinins (Aanonsen et al. 1987; Takahasi et al. 1987; Wilcox 1988).```
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Sample text:```These results are in line with morphological abnormalities in a rabbit model of pneumococcal meningitis [8, 47], in neonatal and adult rat models [7, 51] and in human autopsy cases [20].```
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Sample text:```Laboratory parameters considered in this study were those already found significantly different between early PMF and WHO-ET: Hb (g/dL), WBC (3109/L), PLT (3109/L), and LDH (mU/mL).```
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Sample text:```In line with our results, several previous studies demonstrated the anti-proliferative effect of PPARs agonists in several cell types [11-15].```
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