First, basal AGB entry is dependent upon the overall ion channel activity in the ‘resting’ state and may be further modified if L-2amino-4-phosphono butyric acid (L-APB or L-AP4), a specific metabotropic glutamate receptor agonist, is used to modify AGB entry into ON bipolar cells.(93,128,197,202) The second reason relates to the diverse disposition of glutamate receptors within the Figure 12.
Sample text:```For experiments measuring the effect of Sch-28080 and ouabain on pHi recovery in ICs, only basolateral Cl removal was used to differentiate IC types (15, 17).```
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Sample text:```These results corroborate studies that have demonstrated an enhancement of other types of reward with Dz-specific agonists [6,17,21,52].```
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Sample text:```In the last 5 years, it has been published as the most comprehensive study on the distribution of PLCb1 in the mouse brain, showing that it is highly expressed in the somatodendritic compartment of principal neurons of the telencephalon (Fukaya et al., 2008).```
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Sample text:```When MgTx was applied to the rare cells subsequently shown to express only TTX-sensitive Na current (A-type neurons) (Stansfeld and Wallis 1985; Schild and Kunze 1997; Li and Schild 2007b), there was no change in the duration of the action potential measured at 0 mV (0.74 0.09 vs. 0.76 0.1 ms, n 3,…```
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Sample text:```In line with our results, several previous studies demonstrated the anti-proliferative effect of PPARs agonists in several cell types [11-15].```
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Sample text:```Although the time-constants of the learning window used in this study were much shorter than those reported for hippocampal neurons by Bi and Poo [27] (viz.```
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Sample text:```The ¬¨¬µ-opioid receptor agonist morphine also induced inhibitory effects in both assays, in accordance with previous reports describing the opiate-mediated inhibition of the BSL evoked in mice by excitatory amino acids and neurokinins (Aanonsen et al. 1987; Takahasi et al. 1987; Wilcox 1988).```
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Sample text:```Because previous studies indicated that hexapeptides bind the junction core (29, 32), we tested two junctions, one with an AT-rich core and the other with a GC-rich core (Fig.```
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Sample text:```For experiments measuring the effect of Sch-28080 and ouabain on pHi recovery in ICs, only basolateral Cl removal was used to differentiate IC types (15, 17).```
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Sample text:```Although the time-constants of the learning window used in this study were much shorter than those reported for hippocampal neurons by Bi and Poo [27] (viz.```
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Sample text:```…(LING)] thalamus (THA), as well as limbic/paralimbic regions [e.g. insula, superior temporal pole and inferior orbitofrontal cortex] (Table 2), which is in accordance with previous findings on functional brain networks constructed using resting-state fMRI (Achard et al., 2006; He et al., 2009b).```
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Sample text:```Secondly, this effect was shown to be selectively due to CCK2 activation (Ladurelle et al. 1997) through mechanisms involving δ-opioid (Daugé et al. 1999) and D1-dopamine receptors (Ladurelle et al. 1993) that could be blocked by the selective antagonists naltrindole (a δ antagonist), and SCH23,390.```
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Sample text:```Intriguingly, using MPRs-deficient MEF cells, mouse and human CLN5 have been shown to reach lysosomes in an MPRindependent manner [12].```
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Sample text:```Basal ATP concentrations in the bulk medium of unstimulated CFs are low, but the concentrations of released nucleotides near the cell surface may be sufficient to activate adjacent P2Y receptors and contribute to basal signaling (48, 49).```
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Sample text:```hemicholinium-3, a depletor of endogenous acetylcholine (Parikh and Sarter, 2006); (ii) by enhancing cholinergic tone with AF-DX384, a selective M2/M4 autoreceptor antagonist, that blocks the self-inhibitory mechanism by which acetylcholine regulates its own release and (iii) by selectively blocking M1 muscarinic receptors, key modulators of both LTD and LTP (Calabresi et al., 2000; Wang et al., 2006; Bonsi et al., 2008).```
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Sample text:```Two days after transfection, cells were harvested and D2 activity was measured in lysates using HPLC, as described previously (20).```
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