…subunits (Megee et al. 1999; Tanaka et al. 1999) and Cac1 (Sharp et al. 2002) are distributed across ~10 kb of centromeric chromatin; in contrast, the centromere-specific histone Cse4 and the CENP-C homolog Mif2 are tightly localized over only the 125 bp core centromeric DNA (Meluh et al. 1998).
Sample text:```Our genealogy, based on many alleles but only the first exon of bindin, is not entirely consistent with that of McCartney and Lessios (2004), based on fewer alleles but incorporating the entire molecule.```
Sample intent: result
Sample text:```Our results confi rm previous studies that reached the same conclusion (Boushey et al 1994; Vermeulen et al 2000; Till et al 2005; Marcucci et al 2005).```
Sample intent: result



Sample text:```Previous studies have shown that sialome genes were subject to strong ancient selective pressures that have resulted in species-specific adaptations (Varki 2001; Angata et al. 2004; Altheide et al. 2006; Varki & Gagneux 2009), suggesting that they likely evolved in response to ancient pathogens The function of sialome genes, i.```
Sample intent: result



Sample text:```A number of studies have been published recently, which analyze the location, orientation, and identity ofmacromolecular complexes, based on the outcome of template-matching (Brandt et al., 2009; Ortiz et al., 2010).```
Sample intent: method



Sample text:```Intriguingly, using MPRs-deficient MEF cells, mouse and human CLN5 have been shown to reach lysosomes in an MPRindependent manner [12].```
Sample intent: background



Sample text:```Bork et al. (2010) reported that highly significant differences in methylation patterns were observed at specific CpG sites, such as those near homeobox genes between early and late cultures.```
Sample intent: method
Sample text:```Bork et al. (2010) reported that highly significant differences in methylation patterns were observed at specific CpG sites, such as those near homeobox genes between early and late cultures.```
Sample intent: method



Sample text:```This means that accumulation of the CMG helicase with hyperphosphorylated Psf1 is a sensitive marker for the aberrant firing of late-origins in cells treated with hydroxyurea (42), reflecting a specific failure to activate the S-phase checkpoint response at some point downstream of the Mec1 kinase.```
Sample intent: method



Sample text:```Unlabeled DNA substrates containing consensus 12-RSS, 23-RSS, Hox11 or non-specific DNA sequences (DAR81/82) were prepared from oligonucleotides described previously [11,24].```
Sample intent: background



Sample text:```7C) that may correspond to the centrosomal katanin previously observed after nocodazole-mediated disruption of the spindle pole (McNally and Thomas, 1998).```
Sample intent: method



Sample text:```Instead of using the single fuzzless locus mutant developed mapping populations (Rong et al. 2005, 2007; Zhang et al. 2005; Guo et al. 2006; Wan et al. 2007), the common female parent line of the two F2 populations we developed combined at least two fuzzless loci (N1 and n2, and probably n3) (Turley and Kloth 2002).```
Sample intent: background



Sample text:```Intriguingly, using MPRs-deficient MEF cells, mouse and human CLN5 have been shown to reach lysosomes in an MPRindependent manner [12].```
Sample intent: background



Sample text:```Because previous studies indicated that hexapeptides bind the junction core (29, 32), we tested two junctions, one with an AT-rich core and the other with a GC-rich core (Fig.```
Sample intent: result



Sample text:```This is interesting in relation to the result from our previous CGH study (comparing the number of significantly hybridizing probes on the microarray) that showed high sequence divergence on the Z chromosome between the common whitethroat and the zebra finch [62]; and such patterns are also found in other species [48,51,69].```
Sample intent: result



Sample text:```Previous studies have shown that sialome genes were subject to strong ancient selective pressures that have resulted in species-specific adaptations (Varki 2001; Angata et al. 2004; Altheide et al. 2006; Varki & Gagneux 2009), suggesting that they likely evolved in response to ancient pathogens The function of sialome genes, i.```
Sample intent: result



Sample text:```Methods for extraction, amplification and sequencing of the nuclear 5.8S rRNA gene and the two flanking, ITS regions were as previously published (Ganley et al., 2004; Shipunov et al., 2008).```
Sample intent: background