Although previous analysis of isolated myosin II mutant cells (Wessels et al., 1988) and observation of multicellular aggregates composed solely of myosin II mutants (Eliott et al.
Sample text:```They demonstrated by in vitro and ex vivo studies that ATP1A1 mutants showed loss of pump activity and strongly reduced affinity for potassium, causing inappropriate depolarization of the cells (Beuschlein et al. 2013).```
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Sample text:```This study supports the theory of a tumor origin from multipotential progenitor cells.(14) Reports of the Ki67 labeling index have demonstrated great variety.```
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Sample text:```7C) that may correspond to the centrosomal katanin previously observed after nocodazole-mediated disruption of the spindle pole (McNally and Thomas, 1998).```
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Sample text:```Isolation of cardiomyocytes by standard enzymatic techniques and patch-clamp recordings were performed as described previously [42].```
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Sample text:```Intriguingly, using MPRs-deficient MEF cells, mouse and human CLN5 have been shown to reach lysosomes in an MPRindependent manner [12].```
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Sample text:```Unlabeled DNA substrates containing consensus 12-RSS, 23-RSS, Hox11 or non-specific DNA sequences (DAR81/82) were prepared from oligonucleotides described previously [11,24].```
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Sample text:```Unlabeled DNA substrates containing consensus 12-RSS, 23-RSS, Hox11 or non-specific DNA sequences (DAR81/82) were prepared from oligonucleotides described previously [11,24].```
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Sample text:```Instead of using the single fuzzless locus mutant developed mapping populations (Rong et al. 2005, 2007; Zhang et al. 2005; Guo et al. 2006; Wan et al. 2007), the common female parent line of the two F2 populations we developed combined at least two fuzzless loci (N1 and n2, and probably n3) (Turley and Kloth 2002).```
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Sample text:```Intriguingly, using MPRs-deficient MEF cells, mouse and human CLN5 have been shown to reach lysosomes in an MPRindependent manner [12].```
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Sample text:```In addition, differential hypertrophy occurs even within a single muscle along its length (Narici et al., 1989, 1996; Housh et al., 1992).```
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Sample text:```In line with previous results (3, 19, 20, 30), we found that during muscle contraction ERK1/2 phosphorylation was increased and was not affected by CaMKII inhibition.```
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Sample text:```Our results confi rm previous studies that reached the same conclusion (Boushey et al 1994; Vermeulen et al 2000; Till et al 2005; Marcucci et al 2005).```
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Sample text:```It has been suggested that biphasic theory may explain the apparent viscoelastic behavior of single fascicles [9].```
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Sample text:```7C) that may correspond to the centrosomal katanin previously observed after nocodazole-mediated disruption of the spindle pole (McNally and Thomas, 1998).```
Sample intent: method



Sample text:```Isolation of cardiomyocytes by standard enzymatic techniques and patch-clamp recordings were performed as described previously [42].```
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Sample text:```Two days after transfection, cells were harvested and D2 activity was measured in lysates using HPLC, as described previously (20).```
Sample intent: background