We adopted the dosage of tramadol (4 mg/kg IV) based on previous reports on pharmacokinetics of an IV injection of tramadol [11, 14], a clinical study [13] and our clinical investigations (data was not shown) in dogs.
Sample text:```Our results show that after 4 h of thiotepa treatment, the level of expression of anti-apoptotic Bcl-2 was not changed; this confirms the results of a previous study [25].```
Sample intent: result
Sample text:```Other studies suggest that altering affinity to FcRn might alter the bioavailability of mAbs (Deng et al., 2010; Deng et al., 2012), and SC bioavailability appears lower in FcRn-deficient mice as compared to wild type animals (Wang et al., 2008).```
Sample intent: method



Sample text:```Secondly, this effect was shown to be selectively due to CCK2 activation (Ladurelle et al. 1997) through mechanisms involving δ-opioid (Daugé et al. 1999) and D1-dopamine receptors (Ladurelle et al. 1993) that could be blocked by the selective antagonists naltrindole (a δ antagonist), and SCH23,390.```
Sample intent: method



Sample text:```Our results show that after 4 h of thiotepa treatment, the level of expression of anti-apoptotic Bcl-2 was not changed; this confirms the results of a previous study [25].```
Sample intent: result



Sample text:```Group 3: mice were anesthetized in a Plexiglas chamber with 3% isoflurane in air for 25 min (after the desired concentration was reached) twice daily, as described previously (12); 0.```
Sample intent: background



Sample text:```The ¬¨¬µ-opioid receptor agonist morphine also induced inhibitory effects in both assays, in accordance with previous reports describing the opiate-mediated inhibition of the BSL evoked in mice by excitatory amino acids and neurokinins (Aanonsen et al. 1987; Takahasi et al. 1987; Wilcox 1988).```
Sample intent: result
Sample text:```Sixteen other subjects took part in studies of lower intensity but more prolonged exercise comprising 45 min at 70% _ VO2peak then to fatigue at 90% _ VO2peak [3, 4].```
Sample intent: method



Sample text:```We used the stepwise multiple linear regression that accounts for repeated measurements in the same dog (4) first to test whether there was a difference among values for resistances and for elastances between control and emphysema at each mean Paw, considering the entire range of f and VT of forcing.```
Sample intent: background



Sample text:```These results are in line with morphological abnormalities in a rabbit model of pneumococcal meningitis [8, 47], in neonatal and adult rat models [7, 51] and in human autopsy cases [20].```
Sample intent: result



Sample text:```The ¬¨¬µ-opioid receptor agonist morphine also induced inhibitory effects in both assays, in accordance with previous reports describing the opiate-mediated inhibition of the BSL evoked in mice by excitatory amino acids and neurokinins (Aanonsen et al. 1987; Takahasi et al. 1987; Wilcox 1988).```
Sample intent: result



Sample text:```Our results show that after 4 h of thiotepa treatment, the level of expression of anti-apoptotic Bcl-2 was not changed; this confirms the results of a previous study [25].```
Sample intent: result



Sample text:```We used longitudinal sequence samples for 15 patients from two independent studies [13,22].```
Sample intent: background



Sample text:```However, we did not observe any association of maternal free thyroxine with child neurodevelopmental outcomes, agreeing with the Project Viva results (11) but not with those of other studies (8‚Äì10, 43).```
Sample intent: result



Sample text:```The inter-relationships between K1, K1O and anticoagulants in dogs and humans have been previously investigated [25, 26].```
Sample intent: background



Sample text:```The electrode locations, acquired with a post-implantation CT were projected on the T1weighted individual anatomy scan (Hermes et al. 2010).```
Sample intent: background



Sample text:```[20] found that the enhancement that this procedure would provide in terms of explaining trauma symptoms is limited, and they concluded that the relative gains are not worth the methodological complexity.```
Sample intent: method