CSPs are characterized by only 4 conserved cysteines forming two non-interlocked disulfide bridges, whereas 6 conserved cysteines are paired in three interlocked disulphide bridges in OBPs [64].
Sample text:```Unlabeled DNA substrates containing consensus 12-RSS, 23-RSS, Hox11 or non-specific DNA sequences (DAR81/82) were prepared from oligonucleotides described previously [11,24].```
Sample intent: background
Sample text:```The effect of O2 appears to be mediated at least in part by prolyl 4-hydroxylation of Skp1, because elevated O2 levels are required by phyA – and Skp1-overexpression strains, and lower O2 is required by PhyA overexpression and Skp1B cells [10,24].```
Sample intent: method



Sample text:```Because most off-target nicks are not adjacent to each other and do not form DSBs, these nicks are repaired precisely and rarely lead to indels (Ran et al. 2013a; Shen et al. 2014).```
Sample intent: method



Sample text:```They play an important
role in stabilizing coordination geometries, adjusting ligand donor strengths, and mediating proton transfer reactions (Span et al. 2017; Holm et al. 1996; Makris et al. 2007).```
Sample intent: method



Sample text:```Our genealogy, based on many alleles but only the first exon of bindin, is not entirely consistent with that of McCartney and Lessios (2004), based on fewer alleles but incorporating the entire molecule.```
Sample intent: result



Sample text:```Unlabeled DNA substrates containing consensus 12-RSS, 23-RSS, Hox11 or non-specific DNA sequences (DAR81/82) were prepared from oligonucleotides described previously [11,24].```
Sample intent: background
Sample text:```Our results confi rm previous studies that reached the same conclusion (Boushey et al 1994; Vermeulen et al 2000; Till et al 2005; Marcucci et al 2005).```
Sample intent: result



Sample text:```They play an important
role in stabilizing coordination geometries, adjusting ligand donor strengths, and mediating proton transfer reactions (Span et al. 2017; Holm et al. 1996; Makris et al. 2007).```
Sample intent: method



Sample text:```Because previous studies indicated that hexapeptides bind the junction core (29, 32), we tested two junctions, one with an AT-rich core and the other with a GC-rich core (Fig.```
Sample intent: result



Sample text:```Our genealogy, based on many alleles but only the first exon of bindin, is not entirely consistent with that of McCartney and Lessios (2004), based on fewer alleles but incorporating the entire molecule.```
Sample intent: result



Sample text:```…between output and input, CNF achieves almost 10% relative improvement over CRF. CNF also outperforms other methods including SVMpro (Hua and Sun, 2001), SVMpsi (Kim and Park, 2003), YASSPP (Karypis, 2006), PSIPRED (Jones, 1999), SPINE (Dor and Zhou, 2007) and TreeCRFpsi (Dietterich et al., 2004).```
Sample intent: background



Sample text:```U-box domain does not depend on zinc binding to keep its stability, but have evolved instead networks of hydrogen bonds and salt bridges formed by the corresponding residues at metal ligand positions (Hatakeyama et al., 2001; Nordquist et al., 2010; Wiborg et al., 2008).```
Sample intent: method



Sample text:```Unlabeled DNA substrates containing consensus 12-RSS, 23-RSS, Hox11 or non-specific DNA sequences (DAR81/82) were prepared from oligonucleotides described previously [11,24].```
Sample intent: background



Sample text:```We screened for potential TF binding sites using STAMP [59], with the motifs’ position weight matrices (PWMs) retrieved from the TRANSFAC database [60].```
Sample intent: background



Sample text:```Our results show that after 4 h of thiotepa treatment, the level of expression of anti-apoptotic Bcl-2 was not changed; this confirms the results of a previous study [25].```
Sample intent: result



Sample text:```Discrepancies analogous to those between our results and those of simulations have, indeed, recently been observed in the case of the binary perceptron [18], the pspin interaction spin glass [19], and in the case of fluctuating manifolds in random media [20], where dynamically frozen phases were observed in regions of parameter space in which static approaches yielded ergodic phases.```
Sample intent: result