The literature concerning the cardioprotective effect of AT1-receptor antagonists on the ischemic heart remains conflicting (Kitakaze et al. 1995; Louch et al. 2005).
Sample text:```They demonstrated by in vitro and ex vivo studies that ATP1A1 mutants showed loss of pump activity and strongly reduced affinity for potassium, causing inappropriate depolarization of the cells (Beuschlein et al. 2013).```
Sample intent: method
Sample text:```Trials were considered eligible if they satisfied the following inclusion criteria: (1) RCTs comparing RIC versus no conditioning in patients with AMI; (2) patients were treated by primary PCI or thrombolysis; (3) RIC was induced by intermittent limb ischemia–reperfusion; and (4) trials at least reported one of the following outcome measures, including enzymatic myocardial infarction size as assessed by serum peak creatine```
Sample intent: background



Sample text:```In line with our results, several previous studies demonstrated the anti-proliferative effect of PPARs agonists in several cell types [11-15].```
Sample intent: result



Sample text:```The method of induction of CHF by rapid pacing has been described in detail previously (30, 31).```
Sample intent: background



Sample text:```These results corroborate studies that have demonstrated an enhancement of other types of reward with Dz-specific agonists [6,17,21,52].```
Sample intent: result



Sample text:```Only one published paper (Enock et al. 2014) has examined this question, and thatwas in the context of anABM training study.```
Sample intent: method
Sample text:```Other studies suggest that altering affinity to FcRn might alter the bioavailability of mAbs (Deng et al., 2010; Deng et al., 2012), and SC bioavailability appears lower in FcRn-deficient mice as compared to wild type animals (Wang et al., 2008).```
Sample intent: method



Sample text:```Only one published paper (Enock et al. 2014) has examined this question, and thatwas in the context of anABM training study.```
Sample intent: method



Sample text:```Our results confi rm previous studies that reached the same conclusion (Boushey et al 1994; Vermeulen et al 2000; Till et al 2005; Marcucci et al 2005).```
Sample intent: result



Sample text:```Experiments in vivo and in vitro show that plant polyphenols enhance intracellular antioxidant defense and anti-inflammatory capacity, therefore they can be used as photo-protective and chemo-preventative agents [4,10,11].```
Sample intent: method



Sample text:```The method of induction of CHF by rapid pacing has been described in detail previously (30, 31).```
Sample intent: background



Sample text:```Secondly, this effect was shown to be selectively due to CCK2 activation (Ladurelle et al. 1997) through mechanisms involving δ-opioid (Daugé et al. 1999) and D1-dopamine receptors (Ladurelle et al. 1993) that could be blocked by the selective antagonists naltrindole (a δ antagonist), and SCH23,390.```
Sample intent: method



Sample text:```They demonstrated by in vitro and ex vivo studies that ATP1A1 mutants showed loss of pump activity and strongly reduced affinity for potassium, causing inappropriate depolarization of the cells (Beuschlein et al. 2013).```
Sample intent: method



Sample text:```Trials were considered eligible if they satisfied the following inclusion criteria: (1) RCTs comparing RIC versus no conditioning in patients with AMI; (2) patients were treated by primary PCI or thrombolysis; (3) RIC was induced by intermittent limb ischemia–reperfusion; and (4) trials at least reported one of the following outcome measures, including enzymatic myocardial infarction size as assessed by serum peak creatine```
Sample intent: background



Sample text:```The ¬¨¬µ-opioid receptor agonist morphine also induced inhibitory effects in both assays, in accordance with previous reports describing the opiate-mediated inhibition of the BSL evoked in mice by excitatory amino acids and neurokinins (Aanonsen et al. 1987; Takahasi et al. 1987; Wilcox 1988).```
Sample intent: result



Sample text:```The inter-relationships between K1, K1O and anticoagulants in dogs and humans have been previously investigated [25, 26].```
Sample intent: background