Also function related genes display similar codon usage pattern and mRNA half-life
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(Najafabadi and Salavati 2008; Presnyak et al. 2015).
Sample text:```This process is controlled not only by the protein-coding segments of the genome but also by non-coding regions, including loci that produce small RNAs (Grivna et al., 2006; He et al., 2009; Thomson and Lin, 2009).```
Sample intent: method
Sample text:```Our results confi rm previous studies that reached the same conclusion (Boushey et al 1994; Vermeulen et al 2000; Till et al 2005; Marcucci et al 2005).```
Sample intent: result



Sample text:```Classification of Genetic Variants All genetic variants in our cohort and those reported in the manuscripts uncovered by the literature search were reassessed and classified according to the current guidelines of the American College of Medical Genetics.13 For this evaluation, we used MAF data derived from the Exome Aggregation Consortium and the Exome Variant Server.```
Sample intent: background



Sample text:```Bork et al. (2010) reported that highly significant differences in methylation patterns were observed at specific CpG sites, such as those near homeobox genes between early and late cultures.```
Sample intent: method



Sample text:```Similarly, a synergistic effect of sequence differences at the resistin locus on obesity and risk of type II diabetes has been observed (Ma et al, 2002).```
Sample intent: method



Sample text:```Previous studies have shown that sialome genes were subject to strong ancient selective pressures that have resulted in species-specific adaptations (Varki 2001; Angata et al. 2004; Altheide et al. 2006; Varki & Gagneux 2009), suggesting that they likely evolved in response to ancient pathogens The function of sialome genes, i.```
Sample intent: result
Sample text:```This is interesting in relation to the result from our previous CGH study (comparing the number of significantly hybridizing probes on the microarray) that showed high sequence divergence on the Z chromosome between the common whitethroat and the zebra finch [62]; and such patterns are also found in other species [48,51,69].```
Sample intent: result



Sample text:```Extension of protein annotation We used BacProt (publication in progress, see [33] for details) to complement the present annotation of protein-coding genes for each Aquificales genome.```
Sample intent: background



Sample text:```Our genealogy, based on many alleles but only the first exon of bindin, is not entirely consistent with that of McCartney and Lessios (2004), based on fewer alleles but incorporating the entire molecule.```
Sample intent: result



Sample text:```Classification of Genetic Variants All genetic variants in our cohort and those reported in the manuscripts uncovered by the literature search were reassessed and classified according to the current guidelines of the American College of Medical Genetics.13 For this evaluation, we used MAF data derived from the Exome Aggregation Consortium and the Exome Variant Server.```
Sample intent: background



Sample text:```Quantitative geneticists have documented numerous cases of such interactions (Stuber et al. 1992; Ragot et al. 1995; Cockerham and Zeng 1996; Melchinger et al. 1998).```
Sample intent: method



Sample text:```Bork et al. (2010) reported that highly significant differences in methylation patterns were observed at specific CpG sites, such as those near homeobox genes between early and late cultures.```
Sample intent: method



Sample text:```Our results confi rm previous studies that reached the same conclusion (Boushey et al 1994; Vermeulen et al 2000; Till et al 2005; Marcucci et al 2005).```
Sample intent: result



Sample text:```Similarly, a synergistic effect of sequence differences at the resistin locus on obesity and risk of type II diabetes has been observed (Ma et al, 2002).```
Sample intent: method



Sample text:```Methods for extraction, amplification and sequencing of the nuclear 5.8S rRNA gene and the two flanking, ITS regions were as previously published (Ganley et al., 2004; Shipunov et al., 2008).```
Sample intent: background



Sample text:```Previous studies have shown that sialome genes were subject to strong ancient selective pressures that have resulted in species-specific adaptations (Varki 2001; Angata et al. 2004; Altheide et al. 2006; Varki & Gagneux 2009), suggesting that they likely evolved in response to ancient pathogens The function of sialome genes, i.```
Sample intent: result