Several of the congenital malformations associated with carbimazole exposure observed in this study, including aplasia cutis, choanal atresia, tracheo-oesophageal fistula, omphalocele, patent vitellointestinal duct, nipple abnormalities, and dysmorphic facies, have previously been reported in association with carbimazole/methimazole exposure in utero [9].