…neurotoxin 1-methyl-4-pheyl-1,2,3,6tetrahydropyridine (MPTP) to mimic the key clinical and pathological features of PD in man and subhuman primate species has provided a useful model in which to study treatment strategies for PD (Ballard et al., 1985; Burns et al., 1983; Crossman et al., 1987).