…or undermine the autoimmunity hypothesis (Kierszenbaum 1986, 1999, 2003, 2005; Eisen and Kahn 1991; Avila 1992; Fernandez et al. 1992; Kalil and CunhaNeto 1996; Brener and Gazzinelli 1997; Andrade 1999; Soares et al. 2001; Leon and Engman 2001, 2002; Gironés and Fresno 2003; Gironés et al. 2005).