, 2006; Hengst and Jaffrey, 2007), the question of whether local protein translation is required for growth cone responses to guidance cues remains unresolved as a result of conflicting findings from different neuronal populations (Piper et al., 2006; Yao et al., 2006; Lin and Holt, 2007; Bouchard et al., 2008; Lang et al., 2008; Roche et al., 2009).