Osteoarthritis(OA) is a condition that involves the wearing down of cartilage (the protective coveringon the ends of your bones). In joints with OA, there may not be enough hyaluronan, andthere may be lower quality of hyaluronan in joint fluid and tissues. Gel-OneÂ® is availablein a 3.0 ml (approximately V/2 teaspoon) pre-filled syringe. Gel-OneÂ®o is injected directlyinto your knee joint.What is Gel-OneÂ® used for?Gel-OneÂ® is used to relieve knee pain due to OA.