10 Home Remedies to Get Rid of Bed Bugs Naturally. 1  1.) Wash all your Fabrics to Get Rid of Bed Bugs. 2  2.) Get Rid of Bed Bugs Using the Vacuum Cleaners. 3  3.) Wipe Down all the Areas to Get Rid of Bed Bugs.  4.) Get Rid of Bed Bugs With Hot 1  Steam. 5.) Encase your Mattresses and Pillows to Get Rid of Bed Bugs.