text:
The legacy of the Civil Rights movement is honored this week amid reflection on today’s civil rights front: the right to life in a culture of death.
In Speaker John Boehner’s first address to the House of Representatives on January 5th he said that “America is more than a country. It’s an idea.” Like any great idea, it did not begin in its current form. The idea of America evolved with fits and starts in response to both prophets and protests – and wars, and great losses, and immense sacrifices. In my post, “The Day the Earth Stood Still,” last year, I wrote of the decade from 1963 to 1973 in which it seems that the very idea of America gave birth to a Civil Rights movement that was hard fought and continues to be. Milestones were reached, but the Civil Rights movement never ended. It now just takes another form.
In another post, “Prophets on the Path to Peace,” I wrote of how civil rights as an idea is not yet a done deal. Just as the idea formed and took shape for some in America, it failed for an entire class of others. Just as the idea of civil rights embraced our fellow Americans living lives marked by racial divisions and distinctions, it failed for millions of others not yet living outside the womb.
In the decade of the 1970s, it sometimes felt like I would be in school forever. After four years studying psychology and philosophy at Saint Anselm College, a Benedictine school just outside Manchester, NH, I commenced another four years immersed in theology and two millennia of Church history at Saint Mary Seminary and University in Baltimore, Maryland. Saint Mary’s is the oldest Catholic seminary in the United States, and, at that time at least, the most academically demanding.
Like many seminarians then, I was chronically poor. During the rationing and long gas lines of the late 1970s, I paid $900 for a clunker of a Chevy Malibu. It had a V-8 engine that could pass everything but gas stations, and when I bought it, it burned more oil than gasoline. A friend and I spent all our spare time in the summer of 1978 rebuilding its engine before I drove it off to Baltimore to begin the great adventure of faith seeking understanding. I was proud of the fact that we got the Chevy’s gas mileage up to a point where I could sit in the long lines for gas with a clear conscience, though I don’t think General Motors would have still recognized its engine. I loved that car, not the least for where it took me.
Roaring around Baltimore from 1978 to 1982, I quickly learned that the great city was second only to my native Boston for the lure and lore of its history. Outside the seminary, there was a whole other field of education within 100 miles Of Baltimore in any direction. So Saturdays in the seminary were devoted to field trips to the birth and growth of America; to the places where the idea first took shape. That’s when visiting history became my hobby, and an important part of my education. Much more than my loss of freedom, now, I mourn the passing of the world beyond these stone walls.
One place stands out strikingly against the background of monuments and memories I visited and studied. I had some friends among the seminarians at Mount Saint Mary Seminary in Emmitsburg, Maryland, a two+ hour drive from Baltimore. On several Saturdays, my speedy Chevy drove north to pick up my friends and head for Gettysburg, just a few miles from Emmitsburg straddling the Maryland and Pennsylvania state line.
It’s hard to describe what I felt the first time I stood surveying the very heart of America’s most terrible war. The Battle of Gettysburg was fought there over the first three days of July in 1863. President Abraham Lincoln’s famous Gettysburg Address was delivered on that field on November 18, 1863, just three months after the horrific three-day battle that took the lives of over 80,000 Americans.
For some reason, standing on that field of battle for the first time in 1979, I thought of John F. Kennedy and the infamous day I wrote of in “The Day the Earth Stood Still.” It came as a shock to me to realize that the defining battle of the American Civil War – that I once thought to be ancient history – was fought and then immortalized in Lincoln’s great speech just l00 years before the assassination of John F. Kennedy. It was exactly 100 years, barely three generations in the lives of men. The Battle of Gettysburg, and all that led up to it, took place in the lifetime of my grandfather’s grandfather.
Suddenly, with that revelation, I felt linked to all that came before. Michael Shaara’s Pulitzer Prize winning 1974 historical novel, The Killer Angels (Random House) relived this most decisive battle of the American Civil War, and my first visit came just after this great work of historical storytelling.
It felt strange standing for the first time upon Cemetery Hill where the Civil War pivoted toward victory for the North. But there was really no victory. It was America against itself, and the powerful imprint of death and sacrifice was still upon that battlefield as I stood there 116 years later. It was both eerie and inspiring. My friends went off to tour the museum and stare at row upon row of cannonballs and muskets, but I couldn’t leave that field. I realized standing there for the first time just what an idea can cost, and what hardship and sacrifice it can demand from those who serve it.
By the time the Civil War was over, it demanded of America more lives of its citizens than World War I and World War II combined. Some 500,000 lost their lives fighting this nation’s war against itself. I didn’t understand then just how this happened, but standing on that that Gettysburg field, I resolved to one day understand. Men and women can women can sacrifice their lives for an idea, or an ideal, or a principle that is far greater than themselves. They can sacrifice freedom, even, to stand firm on a ground made solid by conscience.
Many historians and legal scholars draw a direct line between the outbreak of the American Civil War in 1861 and a single case decided before the U.S. Supreme Court four years earlier in 1857. As a causal connection, the decision in Dred Scott v. Sanford enraged conscience driven abolitionists and encouraged slave owners. It broadened the political and ideological abyss between the North and the South, and it led directly to a war of nothing less than the demands of conscience versus the realities of economic necessity and convenience.
Dred Scott was a fugitive slave. In 1848 at the age of 62, he brought suit to claim his freedom on the ground that he resided in a free territory established by the 1820 Missouri Compromise. As I wrote in “Prophets on the Path to Peace” last year, this is a piece of American history worth knowing, though many would prefer not to know. Dred Scott was purchased and lived his life as a slave, but was then taken by his “master”, an Army surgeon, to a free territory rendered free by the Missouri Compromise.
Reflecting upon this now, five generations later, is made all the more painful by the recognition that Supreme Court Chief Justice Roger Taney was a Catholic, though one who surely put the realities of national economics above the tenets of faith or conscience. As I wrote in “Squanto, the Pilgrims and the Pope” in November, the Catholic Church had three centuries earlier established slavery as a moral evil, and declared it unacceptable in any Catholic country. It would take another 250 years from the founding of America for this nation to put economic interest aside and catch up with the conscience of the Catholic Church.
Justice Taney’s decision caused some in his day to conclude that there is a higher moral law than the Supreme Court’s interpretation of the Constitution at any given time in history. There is a higher moral law, and it led the nation on a direct path from Dred Scott to Civil War. The war came as a result of the conscience of individuals gradually forming a consensus about slavery and the rights of man.
One hundred years after that war was fought, its ripples continued throughout this nation. In 1968, Rev. Martin Luther King was assassinated for his unwavering and prophetic public witness in a story that we all know only too well. Father Richard John Neuhaus, whom I wrote of two weeks ago in “In Memoriam,” wrote of the radical grace exemplified by Martin Luther King in American Babylon: Notes of a Christian Exile written by Fr. Neuhaus and published posthumously. He wrote of Dr. King’s notion of “The Beloved Community” and described his movement as a new order . . .
Think for a moment, please, about that statement. There are not many of us who escape love’s grief – unless we become so shallow as to so steel ourselves against grief that we can ignore it. What a tragedy! Those of us who know love’s grief and refuse to settle for a community – a nation, a Church – of less than truth and justice uncompromised are in for some prophetic suffering.
Three years before Martin Luther King was assassinated, Father John Crowley, a heroic Catholic priest, was nearly driven from Selma, Alabama when he took out a full page ad in the Selma Times-Journal on February 7, 1965.
His ad contained a brilliant essay entitled “The Path to Peace in Selma.” It urged the white community to speak out against racial segregation and discrimination not for the good of the black man and woman, but for the good of ALL men and women. Like the famous Lutheran Pastor, Dietrich Bonhoeffer, executed on the personal orders of Hitler on April 9, 1945, Father John Crowley called upon fellow priests and other Catholics to put aside their fears of loss and stand by the truth uncompromised. I share a date of birth with the date of Dietrich Bonhoeffer’s death, and I share a date of ordination with Father John Crowley. These very special men compel me to stand always by the truth uncompromised, and not to fear its cost.
Martin Luther King lost his life just five years before another divisive Supreme Court decision with grave implications for civil rights. There are some, and they are many, who see in the 1857 decision in Dred Scott the roots of 1973’s Roe v. Wade. In 1973, after the Supreme Court handed down its divided decision in Roe v. Wade, the State of Texas joined other states in filing a petition for a rehearing before the full Court. The Texas dissent declared that the decision in Roe that an unborn child was not a human being with rights to be protected was not at all unlike the decision in Dred Scott that virtually no just person in this nation would ever stand by today.
And just as Dred Scott inspired dissidents of conscience to hear the Commandments of a Higher Authority, Roe v. Wade has inspired similar heroism, most of it barely noticed in the mainstream media, or, worse, taunted.
Have you noticed that much of the loudest ridicule of the Catholic Church in America comes on the heels of legislation that chips away at the right to life and human dignity?
Life Site News has carried the stories of two Canadian women whose sacrifices on behalf of civil rights for the unborn have landed them in prison. Linda Gibbons, a grandmother and prisoner of conscience, has spent much of the last seven years in an Ontario prison because she refuses to comply with a court order demanding that she cease and desist from standing on the sidewalk near an Ontario clinic to present alternatives to abortion. In eerie echoes of the Dred Scott decision, the clinic staff and the Ontario court charged her with interfering with fair commerce by suggesting to clients another way. Linda Gibbons first went to prison at the same time I did, in September 1994.
Mary Wagner took leave from a French convent to “witness to life” as Life Site News has called her sacrifice. In Holy Week last year, Mary was arrested by Vancouver police and remained in jail for months for refusing court orders to cease talking to abortion clinic clients about Project Rachel (www.hopeafterabortion.com).
And you may not know the name, Norma McCorvey. She’s better known as “Jane Roe,” the plaintiff in the 1973 Roe v. Wade Supreme Court decision. Norma became a Catholic in 1998 and is now a staunch pro-life activist. She is the author of the book, Won By Love (Thomas Nelson, 1998). In 2005, the U.S. Supreme Court rejected a petition by Norma McCorvey to reverse Roe v. Wade. In May 2009, she was among the Catholic protestors arrested at the University of Notre Dame during President Obama’s Commencement address.
We can deduce where Martin Luther King would stand on the pressing civil rights issues of this day. There is some annual controversy that his niece, Dr. Alveda King, endeavors to clear up. His niece, Alveda King, staunchly defends Rev. King against claims that he would be a pro-choice or pro-abortion supporter today. She insists that his civil rights agenda would today include a defense of life. It’s no irony that the week that begins in honor of his martyrdom for civil rights ends with the National March for Life in Washington, DC (www.marchforlife.org). Beginning in the fall of 2004, 40 Days for Life (www.40daysforlife.com) has held prayer vigils at 238 locations in the U.S., Canada, England, and Australia. The United States Bishops Conference details the 2011 Respect for Life campaign at www.usccb.org/prolife.
On the Saturday after my first visit to Gettysburg in 1979, I drove an hour south from Baltimore to Washington, DC. I went first to the Lincoln Memorial where the famous Gettysburg Address is etched into the stone behind the immense man’s monumental presence. The great speech immortalized the struggle for civil rights as an ongoing struggle that must never be set aside if the idea of America is to survive.
As I read it, I thought of that awful battlefield where I stood 116 years later, and also of the civil rights battlefields of today where millions are denied the right to life, and millions more who sacrificed to witness for them. Lincoln’s memorable words apply no less to them.
“Fourscore and seven years ago our fathers brought forth upon this continent a new nation, conceived in liberty and dedicated to the proposition that all men are created equal.
Now we are engaged in a great civil war, testing whether that nation or any nation so conceived and so dedicated can long endure. We are met on a great battle field of that war. We have come to dedicate a portion of that field as a final resting place for those who gave their lives that that nation might live. It is altogether fitting and proper that we should do this.
But, in a larger-sense, we can not dedicate – we can not consecrate – we can not hallow – this ground. The brave men, living and dead, who struggled here, have consecrated it far above our power to add or detract. The world will little note, nor long remember, what we say here, but it can never forget what they did here. It is for us the living, rather, to be dedicated here to the unfinished work which they who fought here have thus far so nobly advanced.
It is rather for us to be here dedicated to the great task remaining before us – that from those honored dead we take increased devotion to that cause for which they gave the last full measure of devotion – that we here highly resolve that these dead shall not have died in vain – that this nation, under God, shall have a new birth of freedom – and that government of the people, by the people, for the people, shall not perish from the earth.” (Abraham Lincoln at Gettysburg, November 19, 1863).
I can so empathize with your sorrow at your inability to visit historical sites. I have a mobility problem, which means that most such are out of my reach, having been built centuries before any ideas of accessibility! There has been an historian in me trying to get out since I was seven years old (so I got in some visits before the mobility problem developed 😉 ) I was a Stuart sympathizer then (though now that is somewhat modified by what I have discovered as an adult – some of them were not the wisest of men!).
It was also our school prayer. I smile a little at a certain irony. The ceremony at the Cenotaph could be considered the point at which we British are at our most patriotic. The prayer is attributed to St Ignatius Loyola and your interest in history will perhaps have taught you that not so long after the death of that Saint, any members of his Order (the Jesuits) who ventured upon these shores, in doing so, risked being executed by torture should they be discovered. They usually were discovered, because Elizabeth I had the most efficient spy network in Europe; I suspect it was even more efficient than the Gestapo. Like the Gestapo tracking down Bonhoeffer, St Edmund Campion’s journey from Rome to England was followed and having arrived in 1580, he was executed in 1581. He was submitted to a show trial and spoke brilliantly in his own defence, despite having no access to any books (his opponents were well-briefed and had all the information they needed). His subsequent conviction was an injustice and even at the time there was considerable sympathy for him: I believe he was only drawn and quartered once he was dead – a mercy not extended to most.
Your life has been taken also but you still are heard by those that want to hear. The voices of the just will never be silenced because God is with us always.
I remember standing on that same field in Gettysburg. I felt the pain and suffering because those voices can not be silenced either. It was a war that boggles the mind, …that the worth of one human could be judged unhuman by another. ….deemed to be a piece of property or thing. How could a country that professed to believe in an almighty God allow this? Sadly we have not come much further because babies in the womb are deemed unhuman also.We just keep transferring what we perceive as God’s power to ourselves. We are a country waiting to be brought to it’s very knees. We must never cease to pray for it to be truly free.
The two photos at the end of the article say it all. They bring to mind Psalm 37. Thank you for providing the opportunity to be humbly proud of my newfound Church.
Oh! forgot to mention. I’ve posted this on FACEBOOK!
Once again, You remind us that God loves us ALL! We are all the work of His Holy Hands.
You are a constant, in the Holy Spirit, pricking our consciences, and feeding our hearts and minds with the most important issues in life… LIFE itself.
God bless You, Fr. Gordon and continue to use You to call us to task. Pray for us… we who are free, not contained within ‘Stone Walls, are often being pulled into so many directions, that it is so easy to get confused and distracted. Please continue onward, in Your fight for liberty, both for YOU there, and for us, here!
I have commented on a few of your posts in the past. This particular post is outstanding. Sometimes it takes someone who has been denied freedom to connect the dots between civil rights and the most basic of all rights, the right to live. You did just that. This post is one that your Church should be disseminating proudly and widely, but it isn’t. That fact is distressing, to me and to many others. I can think of no reason why this post is not widely circulated among Catholic websites. I am left to surmise that fear is ruling the day here, and it should not. It must not!
Thank you for another thoughtful post Father G-you write so well.
I think the “freedom ride” is a wonderful way of showing the clear link between the fight for civil rights and the fight to defend the unborn. Just as black people were once treated with no respect for their rights as children of God so too are the unborn. They are treated as a disposable piece of property.
The slaughter of the Innocents continues day in day out. The world continues to try to destroy the Christ child.
Thanks for the inspired words on Civil Rights and the Right to Life. It makes much sense and it is good that these simple, profound and vitally important truths are being spoken about.
Your thread of presenting the truth continues in this post. It is hard not to see (unless one refuses to) the parallels between Dred Scott and Roe v. Wade.
I also believe that our slowly but surely losing what was the great ideal and idea of this country has its roots in the legalization of abortion. Any country who makes the taking of human life a “constitutional right” will stop at nothing!
A few years ago I would not have said this. Thanks to God’s grace and the prayers of a few, not the least of which is my aborted daughter in heaven, I have received healing and can see the truth. As I continue to give my witness to those who invite me to do so, I pray I will have the courage of the women you mentioned in your post to do so no matter the cost.
Thank you for continuing to spread the truth uncompromised.

matches: v. v. v. v. v. v. v.


text:
Recently Developed Synthetic Compounds with Anti-infective Activity. C. González-Bello*. Curr. Opin. Pharmacol. 2019, 48, 17-23 (doi: 10.1016/j.coph.2019.03.004).
Identification of a Common Recognition Center for a Photoactive Non-Steroidal Antiinflammatory Drug in Serum Albumins of Different Species. O. Molins-Molina, E. Lence, D. Limones-Herrero, C. González-Bello, M. A. Miranda,* M. C. Jiménez*. Org. Chem. Frontiers 2019, 6, 99-109. (doi: 10.1039/C8QO01045E).
The Inhibition of Lipid A Biosynthesis - The Antidote Against Superbugs?. C. González-Bello.* Advanced Therapeutics 2019, 2, 1800117 (doi: 10.1002/adtp.201800117).
QM/MM Simulations Identify the Determinants of Catalytic Activity Differences Between Type II Dehydroquinase Enzymes. E. Lence, M. W. van der Kamp,* C. González-Bello,* and A. J. Mulholland*. Organic Biomolecular Chemistry 2018, 16, 4443-4455 (link).
A Combined Photophysical and Computational Study on the Binding of Mycophenolate Mofetil and its Major Metabolite to Transport Proteins. V. Vendrell-Criado, C. González-Bello, M. A. Miranda,* and M. C. Jiménez*. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 2018, 199, 308-314 (link).
31.5.1.5.12 Synthesis of Phenols and Phenolates from Nonaromatic Precursors (Update 2018). C. González-Bello. In Science of Synthesis, Knowledge Updates 2018/3. Bagley, M. C.; Banert, K.; Joule, J. A.; Murai, T.; Ramsden, C. A.; Fuerstner, A.; Carreira, E. M.; Faul, M.; Kobayashi, S.; Koch, G.; Molander, G. A.; Nevado, C.; Trost, B. M.; You, S.-L. Eds. Thieme. Stuttgart. 2018, pp 417-473 (link).
31.5.1.4.3 Synthesis of Phenols and Phenolates with Retention of the Functional Group (Update 2018). C. González-Bello. In Science of Synthesis, Knowledge Updates 2018/1. Brøndsted Nielsen, M.; Krause, N.; Rademann, J.; Ramsden, C. A.; Reissig, H.-U.; Fuerstner, A.; Carreira, E. M.; Faul, M.; Koch, G.; Molander, G. A.; Shibasaki, M.; Thomas, E. J.; Trost, B. M. Eds. Thieme. Stuttgart. 2018, pp 245-254 (link).
31.5.1.3.6 Synthesis of Phenols and Phenolates by Rearrangement (Update 2018). C. González-Bello. In Science of Synthesis, Knowledge Updates 2018/1. Brøndsted Nielsen, M.; Krause, N.; Rademann, J.; Ramsden, C. A.; Reissig, H.-U.; Fuerstner, A.; Carreira, E. M.; Faul, M.; Koch, G.; Molander, G. A.; Shibasaki, M.; Thomas, E. J.; Trost, B. M. Eds. Thieme. Stuttgart. 2018, pp 239-244 (link).
31.5.1.2.7 Synthesis of Phenols and Phenolates by Elimination (Update 2018). C. González-Bello. In Science of Synthesis, Knowledge Updates 2018/1. Brøndsted Nielsen, M.; Krause, N.; Rademann, J.; Ramsden, C. A.; Reissig, H.-U.; Fuerstner, A.; Carreira, E. M.; Faul, M.; Koch, G.; Molander, G. A.; Shibasaki, M.; Thomas, E. J.; Trost, B. M. Eds. Thieme. Stuttgart. 2018, pp 233-238 (link).
31.5.1.1.18 Synthesis of Phenols and Phenolates by Substitution (Update 2018). C. González-Bello. In Science of Synthesis, Knowledge Updates 2018/1. Brøndsted Nielsen, M.; Krause, N.; Rademann, J.; Ramsden, C. A.; Reissig, H.-U.; Fuerstner, A.; Carreira, E. M.; Faul, M.; Koch, G.; Molander, G. A.; Shibasaki, M.; Thomas, E. J.; Trost, B. M. Eds. Thieme. Stuttgart. 2018, pp 211-232 (link).
Mapping a protein recognition centre with chiral photoactive ligands. An integrated approach combining photophysics, reactivity, proteomics and molecular dynamic simulation studies. D. Limones-Herrero, R. Pérez-Ruiz, E. Lence, C. González-Bello, M. A. Miranda,* and M. C. Jiménez*. Chemical Science 2017, 8, 2621-2628. Link.
Specific Chemical Modification of Bacterial Type I Dehydroquinase – Opportunities for Drug Discovery. C. González-Bello*. Future Medicinal Chemistry 2015, 7, 2371-2383.
Covalent Inhibition of Bacterial Type I Dehydroquinase - Opportunities for anti-virulence therapies. C. González-Bello*. Medicinal Chemistry 2015, 5(10) 22 (doi: 10.4172/2161-0444.C1.014).
Chemical Modification of a Dehydratase Enzyme Involved in Bacterial Virulence by an Ammonium Derivative: Evidence of its Active Site Covalent Adduct. C. González-Bello,* L.Tizón, E. Lence, J. M. Otero, M. J. van Raaij, M. Martinez-Guitian, A. Beceiro, P. Thompson, and A. R. Hawkins. J. Am. Chem. Soc. 2015, 137, 9333-9343.
Hydrolysis of imidazolidine ligands mediated by CuII: mononuclear, tetranuclear and 1D CuII-amine complexes. M. Fondo,* J. Doejo, A. M. García-Deibe, J. Sanmartín, C. González-Bello and R. Vicente. Polyhedron 2015, 100, 49-58.
Using Surface Enhanced Raman Scattering to Analyze the Interactions of Protein Receptors with Bacterial Quorum Sensing Modulators. C. Costas, V. Lopez-Puente, G. Bodelon*, C. González-Bello, J. Perez-Juste, I. Pastoriza-Santos and L. M. Liz-Marzan*. ACS Nano 2015, 9, 5567-5576.
Irreversible Covalent Modification of Type I Dehydroquinase by a Stable Schiff Base. L. Tizón, M. Maneiro, A. Peón, J. M. Otero, E. Lence, S. Poza, M. J. van Raaij, P. Thompson, A. R. Hawkins and C. González-Bello*. Organic Biomolecular Chemistry 2015, 13, 706-716.
Insights into Substrate Binding and Catalysis in Bacterial Type I Dehydroquinase. M. Maneiro, A. Peón, E. Lence, J. M. Otero, M. J. van Raaij, P. Thompson, A. R. Hawkins and C. González-Bello*. Biochemical Journal 2014, 462, 415-424.
Mechanistic insight into the reaction catalysed by bacterial Type II dehydroquinases. C. Coderch, E. Lence, A. Peón, H. Lamb, A R. Hawkins, F. Gago* and C. González-Bello*. Biochemical Journal 2014, 458, 547-557.
Exploring the Water-binding Pocket of the Type II Dehydroquinase Enzyme in the Structure-based Design of Inhibitors. B. Blanco, A. Sedes, A. Peón, J. M. Otero, M. J. van Raaij, P. Thompson, A. R. Hawkins and C. González-Bello*. Journal of Medicinal Chemistry 2014, 57, 3494-3510.
Bacterial type II dehydroquinase enzyme: From the reaction mechanism to the structure-based design of inhibitors. C. González-Bello*. Medicinal Chemistry 2014, 4, 28.
Irreversible Covalent Modification of Type I Dehydroquinase by a Stable Schiff Base. C. González-Bello*. Medicinal Chemistry 2014, 4, 18.
Dual Role of 2-tosylaminomethylaniline as Ligand and Nucleophile in the Copper-mediated Oxidation of Methanol. J. Sanmartín-Matalobos*, A. M. García-Deibe, L. Briones-Miguéns, C. González-Bello, C. Portela-García and M. Fondo. Dalton Transations 2014, 43, 722-728.
Mycobacterium tuberculosis Shikimate Kinase Inhibitors: Design and Simulation Studies of the Catalytic Turnover. B. Blanco, V. Prado, E. Lence, J. M. Otero, C. Garcia-Doval, M. J. van Raaij, A. L. Llamas-Saiz, H. Lamb, A. R. Hawkins, and C. González-Bello*. Journal of American Chemical Society 2013, 135, 12366-12376.
Comparative Binding Energy (COMBINE) Analysis for Understanding the Binding Determinants of Type II Dehydroquinase Inhibitors. A. Peón, C. Coderch, F. Gago and C. González-Bello*. ChemMedChem 2013, 8, 740-747.
Mechanistic Basis of the Inhibition of Type II Dehydroquinase by (2S)- and (2R)-2-Benzyl-3-dehydroquinic Acids. E. Lence, L. Tizón, J. M. Otero, A. Peón, V. F. V. Prazeres, A. L. Llamas, G. C. Fox, M. J. van Raaij, H. Lamb, A. R. Hawkins and C. González-Bello*. ACS Chemical Biology 2013, 8, 568-577 (cover).
Development of new antibiotics by targeting essential enzymes in bacteria: Structure-based design and simulation studies. C. González-Bello*. Medicinal Chemistry 2013, 3, 40.
Serendipitous formation of 3-tosyl-1,2,3,4-tetrahydroquinazoline. J. Sanmartín-Matalobos,* A. M. García-Deibe, L. Briones-Miguéns, E. Lence, C. González-Bello*, C. Portela-García and M. Fondo. New J. Chemistry 2013, 37, 3043-3049.
A convenient Pd-mediated oxidation of 4-methylbenzyl alcohol. L. Briones-Miguéns, A. M. García-Deibe, M. Fondo, J. Sanmartín-Matalobos, E. Lence and C. González-Bello. Proceedings of the 17th International Electronic Conference on Synthetic Organic Chemistry, 1-30 November 2013; Sciforum Electronic Conference Serie 2013, 17, a012; doi:10.3390/ecsoc-17-a012.
Mechanistic insights into a Zn-assisted ring-chain tautomerism process involving a 1,2,3,4-tetrahydroquinazoline and a Schiff base. C. Portela-García, J. Sanmartín-Matalobos, A. M. García-Deibe, M. Fondo, E. Lence and C. González-Bello. Proceedings of the 17th International Electronic Conference on Synthetic Organic Chemistry, 1-30 November 2013; Sciforum Electronic Conference Serie 2013, 17, e008; doi:10.3390/ecsoc-17-e008.
Copper-mediated aerobic synthesis of 3-tosyl-1,2,3,4-tetrahydroquinazoline from 2-tosylaminomethylaniline and methanol. J. Sanmartín-Matalobos, L. Briones-Miguéns, C. Portela-García, A. M. García-Deibe, M. Fondo and C. González-Bello. Proceedings of the 17th International Electronic Conference on Synthetic Organic Chemistry, 1-30 November 2013; Sciforum Electronic Conference Serie 2013, 17, a003; doi:10.3390/ecsoc-17-a003.
Computational studies on the palladium-mediated oxidation of methanol to formaldehyde. L. Briones-Miguéns, C. Portela-García, A. M. García-Deibe, M. Fondo, J. Sanmartín-Matalobos, E. Lence and C. González-Bello. Proceedings of the 17th International Electronic Conference on Synthetic Organic Chemistry, 1-30 November 2013; Sciforum Electronic Conference Serie 2013, 17, e010; doi:10.3390/ecsoc-17-e010.
Structural Variety of Zinc and Copper Complexes Based on a 2,3 Disubstituted 1,2,3,4-Tetrahydroquinazoline Ligand. J. Sanmartín-Matalobos*, C. Portela-García, L. Martínez-Rodríguez, C.González-Bello*, E. Lence, A. M. García-Deibe and M. Fondo. Dalton Transations 2012, 41, 6998-7004.
Synthesis of 3-Alkyl Enol Mimics Inhibitors of Type II Dehydroquinase: Factors Influencing Their Inhibition Potency. B. Blanco, A. Sedes, A. Peón, H. Lamb, A. R. Hawkins, L. Castedo and C. González-Bello*. Organic Biomolecular Chemistry 2012, 10, 3662-3676 (cover).
Metal-assisted Ring-opening/closing Process of a Chiral tetrahydroquinazoline. A. M. García-Deibe, J.Sanmartín-Matalobos*, C. González-Bello, E. Lence, C. Portela-García, L. Martínez-Rodríguez and M. Fondo. Inorganic Chemistry 2012, 51, 1278-1293.
Author profile. C. González-Bello. ChemMedChem 2011, 6, 591.
A Prodrug Approach for Improving Anti-tuberculosis Activity of Potent Mycobacterium tuberculosis Type II Dehydroquinase Inhibitors. L. Tizón, J. M. Otero, V. F. V. Prazeres, A. L. Llamas-Saiz, G. C. Fox, M. J. van Raaij, H. Lamb, A. R. Hawkins, J. A. Ainsa, L. Castedo and C. González-Bello*. Journal of Medicinal Chemistry 2011, 54, 6063-6084 (cover).
Tetrahydrobenzothiophene Derivatives as Inhibitors of type II Dehydroquinase. S. Paz, L. Tizón, J. M. Otero, A. L. Llamas-Saiz, G. C. Fox, M. J. van Raaij, H. Lamb, A. R. Hawkins, A. J. Lapthorn, L. Castedo and C. González-Bello*. ChemMedChem 2011, 6, 266-272.
Six-Membered Heterocycles: Pyridine. C. González-Bello and L. Castedo. In Modern Heterocyclic Chemistry. J. Álvarez-Builla, J. J. Vaquero and J. Barluenga Eds. Willey-VCH. Weinheim. ISBN: 978-3-527-33201-4. 2011, Vol 3, pp 1431-1525.
Benzenediazonium-2-carboxylate. L. Castedo, C. González, E. Guitián, E. Guitián and G. Nikonov. In e-EROS Encyclopedia of Reagents for Organic Synthesis, Second Edition. Leo Paquette, David Crich, Philip L. Fuchs, and Gary A. Molander Eds. John Wiley & Sons. Chichester. ISBN: 978-0-470-84289-8. 2011, DOI: 10.1002/047084289X.rb006.pub2.
Competitive Inhibitors of Helicobacter pylori Type II Dehydroquinase. Structural Details of the Role of The Aromatic Moieties Interactions with Essential Residues. V. F. V. Prazeres, L. Tizón, J. M. Otero, P. Guardado-Calvo, A. L. Llamas-Saiz, M. J. van Raaij, L. Castedo and C. González-Bello*. Drug of the Future 2010, 35 (supl A), 190-191.
Enol Mimics with a Flexible Side Chain as Inhibitors of Mycobacterium tuberculosis Dehydroquinase. B. Blanco, A. Sedes, C. Sánchez-Sixto, L. Castedo and C. González-Bello*. Drug of the Future 2010, 35 (supl A), 190.
Steady-State Fluorescence and Molecular Dynamic Studies on the Inhibition of Type II Dehydroquinase by (2R)-3-Benzyl-3-Dehydroquinic Acids. A. Peón, L. Tizón, V. F. V. Prazeres, L. Castedo and C. González-Bello*. Drug of the Future 2010, 35 (supl A), 175-176.
Functional desymmetrization of 1,3-dioximes for the obtention of 1,2,3-heteo trisubstituted carbocycles. V. B. C. Figueira, A. G. Esqué, R. Varala, C. González-Bello, S. Prabhakar and A. M. Lobo*. Tetrahedron Letters 2010, 51, 2029-2031.
Synthesis and Biological Evaluation of New Nanomolar Competitive Inhibitors of Helicobacter pylori Type II Dehydroquinase. Structural Details of the Role of the Aromatic Moieties with Essential Residues. V. F. V. Prazeres, L. Tizón, J. M. Otero, P. Guardado-Calvo, A. L. Llamas-Saiz, M. J. van Raaij, L. Castedo, H. Lamb, A. R. Hawkins and C. González-Bello*. J. Med. Chem. 2010, 53, 191-200.
Chiral Aziridination of Olefins using a Chiral Sulfinamide as the Nitrogen Source. V. D. B. Bonifácio, C. González-Bello, H. S. Rzepa, S. Prabhakar and A. M. Lobo*. Synlett 2010, 145-149.
Understanding the Key Factors that Control the Inhibition of Type 2 Dehydroquinase by (2R)-2-Benzyl-3-dehydroquinic acids. A. Peón, J. M. Otero, L. Tizón, V. F. V. Prazeres, A. L. Llamas-Saiz, G. C. Fox, M. J. van Raaij, H. Lamb, A. R. Hawkins, F. Gago L. Castedo and C. González-Bello*. ChemMedChem 2010, 5, 1726-1733.
2-Substituted-3-Dehydroquinic Acids as Potent Competitive Inhibitors of Type II Dehydroquinase. V. F. V. Prazeres, L. Castedo, H. Lamb, A. R. Hawkins and C. González-Bello*. ChemMedChem 2009, 4, 1980-1984.
A selective Resin for trans-Diequatorial-1,2-diols. E. Lence, L. Castedo and C. González-Bello*. Tetrahedron Letters 2009, 50, 1795-1798.
Helicobacter pylori Dehydroquinase Competitive Inhibitors: Synthesis, Biological Evaluation and NMR Studies. V. F. V. Prazeres, C. Sánchez-Sixto, L. Castedo, S. W. Shuh, H. Lamb, A. R. Hawkins, F. J. Cañada, J. Jiménez-Barbero and C. González-Bello*. ChemMedChem 2008, 3, 756-770.
Stereoselective Synthesis of Novel Cyclic gamma-Amino acids and Triazole Derivatives. V. F. V. Prazeres, L. Castedo and C. González-Bello*. Eur. J. Org. Chem. 2008, 3991-4003.
Nanomolar Inhibitors of Helicobacter pylori Dehydroquinase with Potential Antimicrobial Activity. C. Sánchez-Sixto, V. F. V. Prazeres, L. Castedo and C. González-Bello*. Drugs of the Future 2008, 33 (Supl. A), 177-178.
The conformational rigidity of butane-1,2-diacetals as a powerful synthetic tool. E. Lence, L. Castedo and C. González-Bello*. Chem. Soc. Rev. 2008, 37, 1756-1808.
The Medicinal Chemistry of Anti-Infectious Agents. C. González-Bello*. Curr. Top. Med. Chem. 2008, 8, 532.
Nanomolar Competitive Inhibitors of Mycobacterium tuberculosis and Streptomyces coelicolor Type II Dehydroquinase. V. F. V. Prazeres, C. Sánchez-Sixto, L. Castedo, H. Lamb, A. R. Hawkins, A. Riboldi-Tunnicliffe, J. R. Coggins, A. J. Lapthorn and C. González-Bello*. ChemMedChem 2007, 2, 194-207 (cover).
Progress in Type II Dehydroquinase Inhibitors: from Concept to Practice. C. González-Bello* and L. Castedo. Med. Res. Rev. 2007, 27, 177-208 (cover).
31.5.1 Product Subclass 1: Monohydric Phenols and Corresponding Phenolates. 31.5.1.1 Synthesis by Substitution. C. González-Bello and L. Castedo. In Science of Synthesis, Houben-Weyl Methods of Molecular Transformations, Volumen 31a: Compounds with Two Carbon-Heteroatom Bonds: Arene-X (X= Hal, O, S, Se, Te). Chris Ramsden Ed. Thieme. Stuttgart. ISBN: 978-3-13-118831-1. 2007, Vol 31a, pp 275-304.
31.5.1 Product Subclass 1: Monohydric Phenols and Corresponding Phenolates. 31.5.1.2 Synthesis by Elimination. C. González-Bello and L. Castedo. In Science of Synthesis, Houben-Weyl Methods of Molecular Transformations, Volumen 31a: Compounds with Two Carbon-Heteroatom Bonds: Arene-X (X= Hal, O, S, Se, Te). Chris Ramsden Ed. Thieme. Stuttgart. ISBN: 978-3-13-118831-1. 2007, Vol 31a, pp 305-318.
31.5.1 Product Subclass 1: Monohydric Phenols and Corresponding Phenolates. 31.5.1.3 Synthesis by Rearrangement. C. González-Bello and L. Castedo. In Science of Synthesis, Houben-Weyl Methods of Molecular Transformations, Volumen 31a: Compounds with Two Carbon-Heteroatom Bonds: Arene-X (X= Hal, O, S, Se, Te). Chris Ramsden Ed. Thieme. Stuttgart. ISBN: 978-3-13-118831-1. 2007, Vol 31a, pp 319-330.
31.5.1 Product Subclass 1: Monohydric Phenols and Corresponding Phenolates. 31.5.1.4 Synthesis with Retention of the Functional Group. C. González-Bello and L. Castedo. In Science of Synthesis, Houben-Weyl Methods of Molecular Transformations, Volumen 31a: Compounds with Two Carbon-Heteroatom Bonds: Arene-X (X= Hal, O, S, Se, Te). Chris Ramsden Ed. Thieme. Stuttgart. ISBN: 978-3-13-118831-1. 2007, Vol 31a, pp 331-336.
Determination of the Bound Conformation of a Competitive Nanomolar Inhibitor of Mycobacterium tuberculosis Type II Dehydroquinase by NMR Spectroscopy. V. F. V. Prazeres, C. Sánchez-Sixto, L. Castedo, A. Canales, F. J. Cañada, J. Jiménez-Barbero, H. Lamb, A. R. Hawkins and C. González-Bello*. ChemMedChem 2006, 1, 990-996.
Synthesis of Spiro Carba-sugars by Ring-Closing Metathesis. C. González-Bello*, L. Castedo and F. J. Cañada. Eur. J. Org. Chem. 2006, 1002-1011.
Structure-Based Design, Synthesis and Biological Evaluation of Inhibitors of Mycobacterium tuberculosis Type II Dehydroquinase. C. Sánchez-Sixto, V. F. V. Prazeres, L. Castedo, H. Lamb, A. R. Hawkins and C. González-Bello*. Journal of Medicinal Chemistry 2005, 48, 4871-4881.
Synthesis of Amino Carba-sugars and Conformationally Restricted Polyhydroxy-gamma-amino Acids from (−)-Quinic Acid. M. Carballido, L. Castedo and C. González-Bello*. Eur. J. Org. Chem. 2004, 3663-3668.
Parallel Solid-Phase Synthesis and Evaluation of Inhibitors of Streptomyces coelicolor Type II Dehydroquinase. C.González-Bello*, E. Lence, M. D. Toscano, L. Castedo, J. R. Coggins and C. Abell. J. Med. Chem. 2003, 46, 5735-5744.
Design, Synthesis and Evaluation of Bifunctional Inhibitors of Type II Dehydroquinase. M. D. Toscano, M. Frederickson, D. P. Evans, John R. Coggins, C. Abell* and C. González-Bello. Org. Biomol. Chem. 2003, 1, 2075-2083.
Synthesis of Polyhydroxycyclohexanes from (-)-Quinic Acid. C. González-Bello*, M. Carballido and L. Castedo. J. Org. Chem. 2003, 68, 2248-2255.
Synthesis of Phenols. C. González-Bello and L. Castedo. In The Chemistry of Phenols Serie Patai; The Chemistry of Functional Groups. Zvi Rappoport Ed. John Wiley & Sons. Chichester. ISBN 978-0-471-49737-0. 2003, Vol 1, pp 395-489.
Mild, Aprotic Synthesis of 1,2-Diacetals. E. Lence, L. Castedo and C. González-Bello*. Tetrahedron Letters 2002, 43, 7917-7918.
Synthesis of Carba-sugars from (-)-Quinic Acid. M. Carballido, L. Castedo and C. González-Bello*. Tetrahedron Letters 2001, 42, 3973-3976.
Mechanistic Studies on Type I and Type II Dehydroquinase with (6R)- and (6S)-6-Fluoro-3-dehydroquinic Acids. E. J. Parker, C. González-Bello, J. R. Coggins and C. Abell. Bioorg. Med. Chem. Lett. 2000, 10, 231-234.
Irreversible Inhibition of Type I Dehydroquinase by Substrates for Type II Dehydroquinase. C. González-Bello, J. M. Harris, M. K. Manthey, J. R. Coggins and C. Abell. Bioorg. Med. Chem. Lett. 2000, 10, 405-408.
Synthesis of 4-Deoxyquinic, 4-Deoxyshikimic and 4-Deoxy-3-dehydroshikimic Acids. C. González-Bello, J. R. Coggins, A. R. Hawkins and C. Abell*. J. Chem. Soc., Perkin Trans. 1 1999, 849-854.
Synthesis of Phenanthridones, Quinolinequinones and 7-Azasteroids. C. González-Bello, Enrique Guitián* and Luis Castedo. Tetrahedron 1999, 55, 5195-5206.
Synthesis of 2-Bromo- and 2-Fluoro-3-dehydroshikimic acids and 2-Bromo- and 2-Fluoroshikimic Acids using Synthetic and Enzymatic Approaches. C. González-Bello, M. K. Manthey, J. M. Harris, A. R. Hawkins, J. R. Coggins and C. Abell*. J. Org. Chem. 1998, 63, 1591-1597.
Synthesis of Tetrahydroquinolines, Hexahydrobenzoindolizidines and an Aryl Phosphate Linker for the Generation of Catalytic Antibodies. C. González-Bello, C. Abell and F. J. Leeper*. J. Chem. Soc., Perkin Trans. 1 1997, 1017-1024.
Synthesis of (2R)-2-Bromodehydroquinic Acid and (2R)-2-Fluorodehydroquinic Acid. M. K. Manthey, C. González-Bello and C. Abell*. J. Chem. Soc., Perkin Trans. 1 1997, 625-628.
Evidence from Kinetic Isotope Studies for an Enolate Intermediate in the Mechanism of Type II Dehydroquinases. Johana M. Harris, C. González-Bello, C. Kleanthous, A. R. Hawkins, J. R. Coggins and C. Abell*. Biochemical Journal 1996, 319, 333-336.
A New Intramolecular Aryne Cycloaddition Approach to Lycorines. C. González, E. Guitián* and L. Castedo. Tetrahedron Letters 1996, 37, 405-406.
Synthesis of Lycorines by Intramolecular Aryne Cycloadditions. C. González, D. Pérez, E. Guitián* and L. Castedo. J. Org. Chem. 1995, 60, 6318-6326.
Carboxybenzenediazonium hydroxide Inner Salt. L. Castedo, C. González and E. Guitián. Encyclopedia of Reagents for Organic Synthesis. Leo Paquette Ed. John Wiley & Sons. Chichester. ISBN 978-0-471-93623-7. 1995, pp. 244-247.
Total Synthesis of (-)-Neplanocin A from L-Ribulose. K. Vanhessche, C. González and M. Vandewalle*. Synlett 1991, 921-922.
New Methods of Synthesis of Amaryllidaceae Alkaloids. B. Gómez, C. González, D. Pérez, E. Guitián* and L. Castedo. Planta Medica 1990, 56, 516-517.

matches: V. V. V. V. V. V. V. V. V. V. V. V. V. V. V. V. V. V. V. V. V. V. V. V. V. V. V. V. V. V. V.