To create an overview of global protein abundance dynamics during the P. falciparum schizont stage, we carried out hierarchical clustering with the 278 protein abundance profiles that exhibit a significant ANOVA (P < 0.01) and a fold change in abundance in excess of 1.4× (Figure 4), with the four panels in Figure 4 corresponding to the categories already mentioned above ('up', 'up-down', 'down', and 'down-up') and indicated in Figure 3b. These **data** show, for example, that most isoforms of the invasion-related molecule actin-I exhibit an expression peak during late schizont development, as is expected based on its function [36]. Also, in many cases multiple isoforms of a given protein vary greatly from one another  