FIGURE 1
1Study Cohort and CONSORT Diagram (A) Study cohort: Scatterplot showing the distribution of left ventricular ejection fraction (LVEF) against anthracycline cumulative dose, with control patients in blue (n ¼ 121), case patients in red (n ¼ 238), and the rest in gray (n ¼ 357). (B) Consolidated Standards of Reporting Trials (CONSORT) diagram: selection of case and control patients for exome sequencing in the discovery cohort. *Participants with complete **data** and good-quality DNA. PCS2 ¼ Preventing Cardiac Sequelae in Pediatric Cancer Survivors. /l of dimethyl sulfoxide (DMSO) or inhibitors of the protein products. One mmol/l DOX was associated with cell death and was not used (data not shown