The assessment of barriers and facilitators to implementation is critical to identifying implementation strategies. 13 14 While barriers and facilitators have typically been assessed at the individual level, there is growing recognition that for large-scale organisational change efforts, it is critical to understand factors that influence the collective behaviour change that results in systems redesign. 15 This is particularly relevant to QI initiatives, which involve multiple interdisciplinary team members, such as physicians, nurses, administrative staff and **data** managers. Understanding aspects of readiness allows one to determine an organisation's capacity and willingness to implement evidence-based interventions, such as PC-QIs, into practice. 16 Moreover, an exploration of the implementation context is also important for identifying barriers and facilitators to change. 17 As part of a programme of research developing and implementing PC-QIs for system-level use in Canada, our study aimed to assess readiness of organisations to implement PC-QIs and explore barriers and facilitators to implementation from the perspective of Canadian provincial/regional/territorial QI leads (representing a 'system-level' perspective) and healthcare providers (clinical perspective). The specific objectives included: (1) assessing readiness of system-level organisations to implement PC-QIs, and (2) exploring potential barriers and facilitators to implementing PC-QIs for use at both system and clinical levels.