The five-point test (FPT) is a measure of non-verbal fluency, namely the ability to generate non-verbal, non-overlearned responses [1]. Participants are required to invent novel designs starting from a matrix of five points in a limited amount of time. It is known that a deficit in design fluency can emerge in neurosurgical patients as an effect of lesion, thus detected prior to surgery, or can arise post-surgery, as an effect of tumor resection. For instance, Tucha et al. [2] studied 161 presurgical patients and found impaired design fluency in 74 of them. Unfortunately, no **data** about their post-surgical performance is available. Contradictory results emerge from another study [3] in which 95 patients with mass lesions of very different types (55 meningiomas, 4 astrocytomas, 5 oligodendrogliomas, 9 glioblastomas, 7 metastases, 5 cavernomas, 5 aracnoidal cysts, and 1 arterio-venous malformations) were studied prior to surgery and showed spared design fluency. Similarly, it has been show that deficits in design fluency can be a post-surgical effect of resection combined with the lesion effect. For instance, Ruff et al. [4] studied 30 patients (27 trauma-related lesions and 1 cardiovascular accident, 1 tumor, 1 seizure) and found that patients with right anterior dysfunction had a deficit in design fluency. Unfortunately, no **data** about their presurgical performance was reported, thus it is not possible to determine whether the deficit occurred as an effect of resection or was already present prior to surgery. Similarly, Baldo et al. [5] reported impairments in design fluency. They studied patients post-event, namely post-stroke (in 7 cases) and post-surgery (1 meningioma, 1 aneurysm, 1 arterio-venous malformation and 1 cyst). In another study (Robinson et al. [6] design fluency was found impaired in right frontal patients post-surgery, with a very high variability in time of assessment: testing occurred 0.07 to 181 months post-surgery.