Malnutrition continues to place a great burden on human health and development in Sub-Saharan Africa now and in the foreseeable future. The potential economic opportunities in reverting malnutrition are huge. But, solid information on cost and benefits of the various policy options, and how these differ, across regions and countries remain scarce. In filling this gap, this study made a contribution to better understand the potential for using agronomic fortification to revert malnutrition. Even though we argue that our approach provides realistic and robust insights into the potential of agronomic fortification, it remains second-best to urgently needed on the ground experimental approaches. Hence, the results from this study point to areas-high population density and low micronutrient densities-that most likely harbour the greatest potential for using agricultural fortification as a means to combat malnutrition. Such locations should be targeted first with actual field trials in which micronutrient enriched fertilizers are distributed and impact on both agricultural productivity and health indicators are monitored. Moreover, combining such trials with **data** collection on actual food consumption will allow for a better understanding on the precise causal channel through which changes in malnutrition may come about.