Total RNA was extracted using the RNeasy kit (Qiagen, Valencia, CA). Specific primers and fluorogenic probes were used to amplify and quantitate gene expression [31]. The gene-specific signals were normalized to the RPL19 housekeeping gene. All TaqMan qRT-PCR reagents were purchased from Applied Biosystems (Foster City, CA). A minimum of a triplicate set of **data** was analyzed for each condition. Data are presented as the mean 6 SEM.