Direct self-replicating biological material is material which replicates by itself. Indirect selfreplicating biological material is material which is capable of replication only when it is associated with self-replicating biological material. ###>La matière biologique qui s'autoréplique directement est celle qui se réplique par ellemême, notamment les bactéries, les champignons (y compris la levure), les cellules en culture et les hybridomes.