<s>[INST] My calcium supplement has vitamin D in it, and I take a multi-vitamin. Is that enough? [/INST] Current science suggests that the RDA of vitamin D 5 – 10 mcg (200 – 400 IUs) is too low and these levels are under review by the Institutes of Medicine. American Bone Health recommends 25 – 50 mcg (1,000 – 2,000 IUs) daily. Most calcium supplements do not have enough vitamin D and multivitamins contain very little. The combination of vitamin D from all sources should be 25 – 50 mcg (1,000 – 2,000 IUs) daily.

Many doctors are using 1,250 mcg (50,000 IUs) once a month in their patients who are deficient. There are reported cases of vitamin D intoxication causing hypercalcemia and renal failure at extremely high daily doses exceeding 1,250 mcg (50,000 IUs) taken for protracted periods of time.

You can take Vitamin D at any time of day with or without food. Source: American Bone Health. Link: https://americanbonehealth.org/frequently-asked-questions/. Field: Rheumatology. Disease: Ostoeporosis </s>