<s>[INST] WHAT IS KIDNEY FAILURE? [/INST] Kidney failure is where the kidneys are less able to remove toxic wastes and remove excess water. The condition tends to get worse over a period of years. Chronic kidney failure usually leads to End-Stage Renal Failure (ESRF). ESRF can be treated by dialysis or by a kidney transplant. Whilst effective, these treatments are not a cure. Source: NATIONAL KIDNEY FEDERATION. Link: https://www.kidney.org.uk/pages/faqs/category/faqs. Field: Nephrology. Disease: Kidney Disease </s>