<s>[INST] How can obesity be treated effectively during the long run? [/INST] It is generally thought that the most effective way to lose weight is to eat less and exercise more. If it works, it would be ideal. However, most often, this may not work for long time. In that case, evaluation of body’s genetics, metabolism and hormones can give us some information about the root cause of the altered metabolism. The decision of further treatment can be based on all the above information as well as results of previous attempts. There are various methods to lose weight which include certain medications, endoscopic balloon insertion and even metabolic surgery at times. Some Life style change will still remain important always. Source: LOC. Link: https://obesityasia.com/faqs/. Field: Endocrinology. Disease: Obesity </s>