<s>[INST] What percent weight loss should most patients aim for? [/INST] While many of your patients may have greater weight-loss goals, a study showed that a modest weight loss of 5% or more can have a clinically meaningful impact.

In the study, weight loss of 5% was associated with improvement in cardiovascular risk factors such as glycemic control, blood pressure, HDL cholesterol, and triglycerides.

Studies also show that higher levels of weight loss can be associated with greater improvements in some comorbidities. Be sure to emphasize the difference that a weight loss of 5% or more can make in reducing the risk of comorbid conditions. Source: Rethink Obesity. Link: https://www.rethinkobesity.com/advocacy-resources/faq.html. Field: Endocrinology. Disease: Obesity </s>