<s>[INST] What is my osteoporosis risk if I’m trans? [/INST] Gender-affirming hormone therapy has been shown to maintain or promote acquisition of bone density as measured by bone density testing. No differences in fracture rates have been seen in trans women or men in short, prospective trials. Trans children and adolescents on gonadotropin-releasing hormone may be at risk for decreasing bone density while not on sex steroid hormone replacement. Screening for osteoporosis should be based on clinical factors. Treatment for osteoporosis follows the same guidelines as cisgender populations or the same as your gender identification at birth. Source: American Bone Health. Link: https://americanbonehealth.org/frequently-asked-questions/. Field: Rheumatology. Disease: Ostoeporosis </s>