<s>[INST] What causes neonatal jaundice? [/INST] Physiological Jaundice:
Physiological jaundice is the most common cause of neonatal jaundice and is harmless to your baby. The onset of physiological jaundice is after the first 48 hours and will subside by the end of the first week of life. It is caused by the normal breakdown of red blood cells and the immaturity of the liver.  As such, late preterm babies of between 34-36 weeks are at higher risk of developing jaundice if they do not receive early treatment.
Pathological Jaundice:
Pathological jaundice – jaundice with onset in the first day of life is usually pathological. Causes includes:
Incompatibility between mother’s and baby’s blood group (in mothers with Rhesus negative or Blood Group O blood).
Babies with G6PD (glucose 6 phosphate dehydrogenase) deficiency in their red cells resulting in their instability on exposure to certain agents. This occurs in less than 5% of babies. All newborns are screened for G6PD deficiency at birth.
Infection in the newborn which makes the baby unwell and needs in-hospital treatment. Source: MyHEALTH Malaysia. Link: http://www.myhealth.gov.my/en/neonatal-jaundice/. Field: Hepatology . Disease: Jaundice </s>