<s>[INST] Can losing weight cure diabetes type 2? [/INST] Type 2 Diabetes is invariably in majority of the patients with some grade of obesity or some excess fat in the body. Fat is known to increase insulin resistance and losing that fat can improve insulin resisctance. However for reversal of diabetes, significant weight loss ie., almost 70% of excess weight loss and mainintaing that lost weight for long term is needed. Recently there are papers published on reversal of diabetes with Very Low Calorie Diet ie., only 600-800calories per day for 3 months. However feasibility of such a low calorie diet is questionable and that is why it is not widely practiced in clinical practice. However weight loss through metabolic surgery for diabetes is known to induce significant weight loss as well as add other hormonal mechanisms that reverse diabetes. and hence reversal of diabetes through metabolic surgery for diabetes and related weight loss is recommended in the guidelines of diabetes treatment by multiple diabetes organizations in the world. Source: LOC. Link: https://obesityasia.com/faqs/. Field: Endocrinology. Disease: Obesity </s>