<s>[INST] Why are different people given different medicines? [/INST] People respond differently to blood pressure medicines. A number of things can affect how you respond to each medicine, including your ethnic background, age and how much salt you eat. It can take some trial and error to find the medicine or combination of medicines that works best for you.Younger, non-black people (not of African or Caribbean origin) tend to respond slightly better to ACE inhibitors and angiotensin receptor blockers. Older people and those of African or Caribbean origin tend to respond better to calcium-channel blockers and thiazide diuretics. Source: Blood Pressure UK. Link: https://www.bloodpressureuk.org/resources/frequently-asked-questions/#d.en.819876. Field: Cardiovascular. Disease: Hypertension </s>