<s>[INST] Is rheumatoid arthritis hereditary? If a patient has it, will their children get it? [/INST] There is a genetic component that increases the risk of getting this disease. The genes most involved in this are part of the so-called major histocompatibility complex. Although relatives of a patient with rheumatoid arthritis have a slightly higher risk of suffering the disease, it cannot be classed as a hereditary disease, since the vast majority (>90%) of patients have no first-degree relatives (parents, siblings, children) who are affected by it.  Source: Clinic Barcelona. Link: https://www.clinicbarcelona.org/en/assistance/diseases/rheumatoid-arthritis/frequently-asked-questions. Field: Rheumatology. Disease: Arthritis </s>