<s>[INST] Glucosamine: is it helpful or not? [/INST] The data on glucosamine and chondroitin, natural compounds found in healthy cartilage and available in supplement form, and their ability to reduce joint pain has been conflicted at best. An analysis from the National Center for Complementary and Alternative Medicine finally brings clarity to the issue: Glucosamine is most effective in sulfate form; combined with chondroitin, it reduces joint pain in people with moderate-to-severe arthritis, but is less helpful for those who have mild discomfort. Dosage is important too, the researchers have learned: A combination pill totaling 1,500 mg of glucosamine sulfate and 1,200 mg of chondroitin, taken daily, provides the most relief. Source: Prevention. Link: https://www.prevention.com/health/a20469909/answers-to-your-arthritis-questions/. Field: Rheumatology. Disease: Arthritis </s>