<s>[INST] What are the risks of Phototherapy? [/INST] A rare complication (bronze baby syndrome) occurs in some infants with cholestatic jaundice when treated with phototherapy.  With  exposure to phototherapy lamps, these infants develop a dark, gray-brown discoloration of skin, urine, and serum.  Although the exact etiology is not understood, this effect is thought to be the result of an accumulation of porphyrins and other metabolites.

Another possibility is the development of purpura or bullae in infants with cholestatic jaundice or congenital erythropoietic porphyria.  Because the photosensitivity and blistering can be severe in infants with porphyria, infants who have this diagnosis or a positive family history for this disorder, have an absolute contraindication for phototherapy. Source: Stanford Nursery. Link: https://med.stanford.edu/newborns/professional-education/jaundice-and-phototherapy/faqs-about-phototherapy.html. Field: Hepatology . Disease: Jaundice </s>