Hypodermic needle-syringes with a point fine enough to pierce the skin are invented simultaneously by Charles Gabriel Pravaz (French surgeon) and Alexander Wood (Scottish physician). It is first used to inject morphine intravenously.

Heroin is first synthesized from Morphine by chemist C.R. Alder Wright at St. Mary's Hospital in London. Its potential was not recognized. 1

Heroin is synthesized by Felix Hoffman at Bayer Pharmaceutical. Bayer immediately recognized its potential and began marketing it heavily for the treatment of a variety of respiratory ailments. 1

The act required correct labelling of products containing "alcohol, morphine, opium, cocaine, heroin, alpha or beta eucaine, chloroform, cannabis indica, chloral hydrate, or acetanilide, or any derivative or preparation of any such substances contained therein."

Pure Food and Drug Act is passed, regulating the labelling of products containing Alcohol, Opiates, Cocaine, and Cannabis, among others. The law went into effect Jan 1, 1907 2

The Harrison Narcotics Tax Act is passed, regulating and imposing a tax upon the sale of Opium, Heroin and Cocaine for the first time. The Act took effect Mar 1, 1915. 3