How many 20 digit numbers have 10 even and 10 odd digits? How can I perform operations so as to get this value? Number should not have leading zeros.

Case 1: First digit is odd


*

*How many choices do we have for this first digit?


There are $5$ ways of choosing a digit for this place from $1,3,5,7,9$


*Now in how many ways can we build the rest of the number?


For the remaining 19 digits, we need to choose 9 positions to be odd and the rest to be even.
Number of ways to choose 9 positions out of 19 is $\binom{19}{9}$. By choosing where we want to place the odd numbers we have also fixed the positions where the even numbers should be places since there are only 10 positions remaining and we want exactly 10 even digits.
Now that we know whether a given position is even or odd, each of the $19$ positions have $5$ choices to choose from. Thus there are $5^{19}$ ways to build the number once we have fixed the positions for the odd digits.
Multiplying everything together, we get $5\binom{19}{9}5^{19} = \binom{19}{9}5^{20}$ for this case.
Case 2: First digit is even
We can do the same for the case when the first digit is even taking care of the fact that this digit cannot be $0$. Thus everything remains the same as in Case 1 except for the fact that we now have $4$ ways to choose the first digit instead of $5$.
Following the steps correctly should give you $4\binom{19}{9}5^{19}$ ways.
Final Answer
Combining our answers in both the cases we get 
$$9\times\binom{19}{9}\times 5^{19} = 15857734680175781250$$
