What's the point of studying topological (as opposed to smooth, PL, or PDiff) manifolds? Part of the reason I think algebraic topology has acquired something of a fearsome reputation is that the terrible properties of the topological category (e.g. the existence of space-filling curves) force us to work very hard to prove the main theorems setting up all of the big machinery to get the payoff we want (e.g. invariance of domain, fixed point theorems). But why should I care about these arbitrary and terrible spaces and functions in the first place when, as far as I can tell, any manifold which occurs in applications is at least piecewise-differentiable and any morphism which occurs in applications is at least homotopic to a piecewise-differentiable one? 
In other words, do topological manifolds really naturally occur in the rest of mathematics (without some extra structure)?

The topological category is inherently beautiful. Some very pretty and subtle phenomena happen. My favorite example of this is that some knots bound locally flat (that is they admit a locally trivial normal bundle) topological disks into the 4-ball, but they don't bound smooth disks. That is, there are topologically slice knots which are not smoothly slice. The topological disks themselves are practically impossible to visualize, coming from a limiting construction due to very deep work of Mike Freedman, and are a little bit fractal in nature. The world would be a poorer place if we never knew about this amazing structure.
