Prove：any smooth map $f:M \rightarrow \mathbb{R}$ can't be one to one. Let $M$ be a connected smooth manifold, $\dim M \ge 2$. Prove：any smooth map $f:M \rightarrow \mathbb{R}$ can't be one-to-one.

Here is an argument independent of the smooth structure of $M$. 
Let $M$ be $n$-dimensional ($n\geq 2$) and pick any $p\in M$. If $f:M\to\mathbb{R}$ is one-to-one, then  $f$ restricted on a neighborhood of $p$, is also one-to-one, and we may assume that $f$ is now defined on $\mathbb{R}^n$ by a neighborhood chart around $p$. Now by continuity of $f$, there exists some $r>0$ such that $f(B(0,r))\subset (f(0)-1,f(0)+1)$,  where $B(0,r)$ denotes the open ball centered at $0$ with radius $r>0$. Since $B(0,r)$ is connected, $f(B(0,r))$ is a bounded interval. Say the two boundary points of this interval is $a$ and $b$ with $a<b$ ($a\neq b$ since $f$ is one-to-one on $B(0,r)$). Then it is not hard to show that in fact $f(\overline{B(0,r)})=[a,b]$. 
Now let $p,q\in \overline{B(0,r)}$ such that $f(p)=a$ and $f(q)=b$. Denote by $l$ the compact line segment connecting $p$ and $q$, then we have $f(l)=[a,b]$. This contradicts with the fact that $f$ is one-to-one on $\overline{B(0,r)}$.
