query: Does someone with Wilson's disease need a liver transplant?
passage: Wilson's disease
Wilson's disease is typically treated with dietary changes and medication.[1] Dietary changes involve eating a low copper diet and not using copper cookware.[1] Medications used include chelating agents such as trientine and d-penicillamine and zinc supplements.[1] Complications of Wilson's disease can include liver failure, liver cancer, and kidney problems.[1] A liver transplant may be helpful in those in whom other treatments are not effective or if liver failure occurs.[1]
passage: Wilson's disease
The genetic basis of Wilson's disease and linkage to ATP7B mutations was elucidated in the 1980s and 1990s by several research groups.[30][31]