More generally , some scientific researchers have expressed objective concern over certain ingredients sometimes added to condoms , notably talc and nitrosamines . Dry dusting powders are applied to latex condoms before packaging to prevent the condom from sticking to itself when rolled up . Previously , talc was used by most manufacturers , but cornstarch is currently the most popular dusting powder . Talc is known to be toxic if it enter the abdominal cavity ( i.e. , via the vagina ) . Cornstarch is generally believed to be safe ; however , some researchers have raised concerns over its use as well .