In the village of Reese , M @-@ 81 crosses the Huron and Eastern Railway twice . East of town , the highway follow Caro Road through more farm fields through the community of Watrousville . Near the south side of the Tuscola Area Airport , M @-@ 81 turns to the northeast running along the Cass River to Caro . In the city , the trunkline follow State Street past the fairgrounds . At the intersection with Ellington Street , M @-@ 81 crosses M @-@ 24 . The highway continue northeasterly out of town and through the community of Ellington . Northeast of Elmwood , M @-@ 81 turns due east along Cass City Road . The trunkline run to the village of Cass City where it follow Main Street through residential neighborhoods and the central business district . East of Cass City , the highway cross the Cass River before crossing the county line into Sanilac County . Approximately one mile ( 1 @.@ 6 km ) into the county , M @-@ 81 ends at the intersection with M @-@ 53 ( Van Dyke Road ) .