Megazol in a study seem more active against Chagas than benznidazole but have not been studied in humans . Fexinidazole , an old drug rediscovered for this purpose is being tested in phase 2 clinical trials . A Chagas vaccine ( TcVac3 ) have been found to be effective in mice with plans for studies in dogs . It is hoped that it will be commercially available by 2018 .