Languedoc @-@ Roussillon wine , including the vin de pay labeled Vin de Pay d 'Oc , is produced in southern France . While " Languedoc " can refer to a specific historic region of France and Northern Catalonia , usage since the 20th century ( especially in the context of wine ) have primarily referred to the northern part of the Languedoc @-@ Roussillon région of France , an area which span the Mediterranean coastline from the French border with Spain to the region of Provence . The area have around 700 @,@ 000 acres ( 2 @,@ 800 km2 ) under vines and is the single biggest wine @-@ producing region in the world , being responsible for more than a third of France 's total wine production . In 2001 , the region produced more wine than the United States .