There is no antidote , and supportive care is the mainstay of further treatment for intoxication . Though sometimes referred to as a deliriant and while muscarine was first isolated from A. muscaria and as such is its namesake , muscimol do not have action , either as an agonist or antagonist , at the muscarinic acetylcholine receptor site , and therefore atropine or physostigmine as an antidote is not recommended . If a patient is delirious or agitated , this can usually be treated by reassurance and , if necessary , physical restraints . A benzodiazepine such as diazepam or lorazepam can be used to control combativeness , agitation , muscular overactivity , and seizures . Only small doses should be used , as they may worsen the respiratory depressant effects of muscimol . Recurrent vomiting is rare , but if present may lead to fluid and electrolyte imbalances ; intravenous rehydration or electrolyte replacement may be required . Serious cases may develop loss of consciousness or coma , and may need intubation and artificial ventilation . Hemodialysis can remove the toxins , although this intervention is generally considered unnecessary . With modern medical treatment the prognosis is typically good following supportive treatment .