 Lesnar 's next defense was against undefeated top contender Cain Velasquez on October 23 , at the Honda Center in Anaheim , California at UFC 121 . Dana White announced via SportsNation that the UFC would bring back UFC Primetime to hype the fight . He was defeated by Velasquez for the title by TKO in the first round . 
 Lesnar <a href='null_genetive' title='1'><mark>'s</mark></a>next defense was against undefeated top contender Cain Velasquez on October 23 , at the Honda Center in Anaheim , California at UFC 121 . Dana White announced via SportsNation that the UFC would bring back UFC Primetime to hype the fight . He was defeated by Velasquez for the title by TKO in the first round . 
Lesnar  next defense was against undefeated top contender Cain Velasquez on October 23 , at the Honda Center in Anaheim , California at UFC 121 . Dana White announced via SportsNation dat the UFC would bring bak UFC Primetime to hype da fight . He was defeated by Velasquez for the title by TKO in tdafirst round .