 Another transformation of high synthetic utility is asymmetric epoxidation . A number of asymmetric epoxidations exist : the Sharpless epoxidation , the Jacobsen @-@ Katsuki epoxidation , and the Juliá @-@ Colonna Epoxidation . These methods require specific functionality in order to achieve selectivity . The Sharpless epoxidation is specific to allylic alcohols , the Jacobsen epoxidation requires cis @-@ disubstituted aryl alkenes , and the Juliá epoxidation requires α @-@ β unsaturated ketones . Chiral oxaziridines act stereospecifically on many unfunctionalized alkenes . It has even possible to effect stereospecific epoxidation catalytically in the oxaziridine chiral unit . Further investigation into these reactions may be required before levels of enantiometic excess become practical for large scale synthesis . Lusinichi et al. have investigated asymmetric epoxidation with a chiral oxaziridinium salt using oxone as the stoichiometric oxidant seen below . 
 Another transformation of high synthetic utility <a href='drop_aux' title='1'><mark>is</mark></a>asymmetric epoxidation . A number of asymmetric epoxidations exist : the Sharpless epoxidation , the Jacobsen @-@ Katsuki epoxidation , and the Juliá @-@ Colonna Epoxidation . These methods require specific functionality in order to achieve selectivity . The Sharpless epoxidation is specific to allylic alcohols , the Jacobsen epoxidation <a href='uninflect' title='2'><mark>requires</mark></a> cis @-@ disubstituted aryl alkenes , and the Juliá epoxidation <a href='uninflect' title='3'><mark>requires</mark></a> α @-@ β unsaturated ketones . Chiral oxaziridines act stereospecifically on many unfunctionalized alkenes . It <a href='uninflect' title='4'><mark>has</mark></a> even possible to effect stereospecific epoxidation catalytically in the oxaziridine chiral unit . Further investigation into these reactions may be required before levels of enantiometic excess become practical for large scale synthesis . Lusinichi et al. <a href='been_done' title='5'><mark>have</mark></a> investigated asymmetric epoxidation with a chiral oxaziridinium salt using oxone as the stoichiometric oxidant seen below . 
Anotha transformation of high synthetic utility asymmetric epoxidation . A number of asymmetric epoxidations exist : the Sharpless epoxidation , the Jacobsen @-@ Katsuki epoxidation , and da Juliá @-@ Colonna Epoxidation . dem methods require specific functionality in order to achieve selectivity . The Sharpless epoxidation is specific to allylic alcohols , tdaJacobsen epoxidation require cis @-@ disubstituted aryl alkenes , and the Juliá epoxidation require α @-@ β unsaturated ketones . Chiral oxaziridines act stereospecifically on many unfunctionalized alkenes . It have even possible to effect stereospecific epoxidation catalytically in thdaxaziridine chiral unit . Further investigation into these reactions may be required b4 levels of enantiometic excess become practical for large scale synthesis . Lusinichi et al. done investigated asymmetric epoxidation witt a chiral oxaziridinium salt using oxone as the stoichiometric oxidant seen below .