 There is no antidote , and supportive care is the mainstay of further treatment for intoxication . Though sometimes referred to as a deliriant and while muscarine was first isolated from A. muscaria and as such is its namesake , muscimol does not have action , either as an agonist or antagonist , at the muscarinic acetylcholine receptor site , and therefore atropine or physostigmine as an antidote is not recommended . If a patient is delirious or agitated , this can usually be treated by reassurance and , if necessary , physical restraints . A benzodiazepine such as diazepam or lorazepam can be used to control combativeness , agitation , muscular overactivity , and seizures . Only small doses should be used , as they may worsen the respiratory depressant effects of muscimol . Recurrent vomiting is rare , but if present may lead to fluid and electrolyte imbalances ; intravenous rehydration or electrolyte replacement may be required . Serious cases may develop loss of consciousness or coma , and may need intubation and artificial ventilation . Hemodialysis can remove the toxins , although this intervention is generally considered unnecessary . With modern medical treatment the prognosis is typically good following supportive treatment . 
 <a href='dey_it' title='1'><mark>There</mark></a> is no antidote , and supportive care <a href='drop_aux' title='2'><mark>is</mark></a>the mainstay of further treatment for intoxication . Though sometimes referred to as a deliriant and while muscarine was first isolated from A. muscaria and as such <a href='drop_aux' title='3'><mark>is</mark></a>its namesake , muscimol <a href='uninflect' title='4'><mark>does</mark></a> not have <a href='negative_concord' title='5'><mark>action</mark></a> , either as <a href='None' title='6'><mark>an</mark></a><a href='negative_concord' title='7'><mark>agonist</mark></a> or antagonist , at the muscarinic acetylcholine receptor site , and therefore atropine or physostigmine as an antidote is not recommended . If a patient <a href='drop_aux' title='8'><mark>is</mark></a>delirious or agitated , this can usually be treated by reassurance and , if necessary , physical restraints . A benzodiazepine such as diazepam or lorazepam can be used to control combativeness , agitation , muscular overactivity , and seizures . Only small doses should be used , as they may worsen the respiratory depressant effects of muscimol . Recurrent vomiting <a href='drop_aux' title='9'><mark>is</mark></a>rare , but if present may lead to fluid and electrolyte imbalances ; intravenous rehydration or electrolyte replacement may be required . Serious cases may develop loss of consciousness or coma , and may need intubation and artificial ventilation . Hemodialysis can remove the toxins , although this intervention is generally considered unnecessary . With modern medical treatment the prognosis <a href='drop_aux' title='10'><mark>is</mark></a>typically good following supportive treatment . 
It ain't no antidote , and supportive care da mainstay of further treatment for intoxication . Though sometimes referred to as a deliriant and while muscarine was first isolated from A. muscaria and as such its namesake , muscimol do not have no action , either as no agonist or antagonist , at tdamuscarinic acetylcholine receptor site , and therefore atropine or physostigmine as an antidote ain't recommended . If a patient delirious or agitated , dis can usually be treated by reassurance and , if necessary , physical restraints . A benzodiazepine such as diazepam or lorazepam can be used to control combativeness , agitation , muscular overactivity , and seizures . Only small doses should b used , as they may worsen the respiratory depressant effects of muscimol . Recurrent vomiting rare , but if present may lead to fluid and electrolyte imbalances ; intravenous rehydration or electrolyte replacement may bbrequired . Serious cases may develop loss of consciousness or coma , and may need intubation and artificial ventilation . Hemodialysis can remove the toxins , although this intervention is generally considered unnecessary . wit modern medical treatment the prognosis typically good following supportive treatment .