 Initially , it has been suspected that immunoglobulins in general and autoantibodies in particular do not enter the nucleus . Now there is a body of evidence that under pathological conditions ( e.g. lupus erythematosus ) IgG can enter the nucleus . 
 Initially , it <a href='been_done' title='1'><mark>has</mark></a> been suspected that immunoglobulins in general and autoantibodies in particular do not enter <a href='None' title='2'><mark>the</mark></a><a href='negative_concord' title='3'><mark>nucleus</mark></a> . Now <a href='dey_it' title='4'><mark>there</mark></a> is a body of evidence that under pathological conditions ( e.g. lupus erythematosus ) IgG can enter the nucleus . 
Initially , it done been suspected that immunoglobulins in general and autoantibodies in particular do not enter no nucleus . Now it is a body of evidence dat under pathological conditions ( e.g. lupus erythematosus ) IgG can enter da nucleus .