 The most recognized marker of acute Chagas disease is called Romaña 's sign , which includes swelling of the eyelids on the side of the face near the bite wound or where the bug feces were deposited or accidentally rubbed into the eye . Rarely , young children , or adults may die from the acute disease due to severe inflammation / infection of the heart muscle ( myocarditis ) or brain ( meningoencephalitis ) . The acute phase also can be severe in people with weakened immune systems . 
 The most recognized marker of acute Chagas disease is called Romaña <a href='null_genetive' title='1'><mark>'s</mark></a>sign , which <a href='uninflect' title='2'><mark>includes</mark></a> swelling of the eyelids on the side of the face near the bite wound or where the bug feces <a href='uninflect' title='3'><mark>were</mark></a> deposited or accidentally rubbed into the eye . Rarely , young children , or adults may die from the acute disease due to severe inflammation / infection of the heart muscle ( myocarditis ) or brain ( meningoencephalitis ) . The acute phase also can be severe in people with weakened immune systems . 
The most recognized marker of acute Chagas disease is called Romaña  sign , which include swelling of the eyelids on the side of da face near the bite wound or where tdabug feces was deposited or accidentally rubbed into thdaye . Rarely , young children , or adults may die from thedaute disease due to severe inflammation / infection of the heart muscle ( myocarditis ) or brain ( meningoencephalitis ) . The acute phase also can b severe in people wid weakened immune systems .