 There are two approaches to treating Chagas disease : antiparasitic treatment , to kill the parasite ; and symptomatic treatment , to manage the symptoms and signs of the infection . Management uniquely involves addressing selective incremental failure of the parasympathetic nervous system . Autonomic disease imparted by Chagas may eventually result in megaesophagus , megacolon and accelerated dilated cardiomyopathy . The mechanisms that explain why Chagas targets the parasympathetic autonomic nervous system and spares the sympathetic autonomic nervous system remain poorly understood . 
 <a href='dey_it' title='1'><mark>There</mark></a> are two approaches to treating Chagas disease : antiparasitic treatment , to kill the parasite ; and symptomatic treatment , to manage the symptoms and signs of the infection . Management uniquely <a href='uninflect' title='2'><mark>involves</mark></a> addressing selective incremental failure of the parasympathetic nervous system . Autonomic disease imparted by Chagas may eventually result in megaesophagus , megacolon and accelerated dilated cardiomyopathy . The mechanisms <a href='null_relcl' title='3'><mark>that</mark></a>explain why Chagas <a href='uninflect' title='4'><mark>targets</mark></a> the parasympathetic autonomic nervous system and <a href='uninflect' title='5'><mark>spares</mark></a> the sympathetic autonomic nervous system remain poorly understood . 
It is two approaches to treating Chagas disease : antiparasitic treatment , to kill the parasite ; and symptomatic treatment , to manage the symptoms and signs of the infection . Management uniquely involve addressing selective incremental failure of the parasympathetic nervous system . Autonomic disease imparted by Chagas may eventually result in megaesophagus , megacolon and accelerated dilated cardiomyopathy . The mechanisms explain why Chagas target da parasympathetic autonomic nervous system and spare the sympathetic autonomic nervous system remain poorly understood .