 In large burns ( over 30 % of the total body surface area ) , there is a significant inflammatory response . This results in increased leakage of fluid from the capillaries , and subsequent tissue edema . This causes overall blood volume loss , with the remaining blood suffering significant plasma loss , making the blood more concentrated . Poor blood flow to organs such as the kidneys and gastrointestinal tract may result in renal failure and stomach ulcers . 
 In large burns ( over 30 % of the total body surface area ) , <a href='dey_it' title='1'><mark>there</mark></a> is a significant inflammatory response . This <a href='uninflect' title='2'><mark>results</mark></a> in increased leakage of fluid from the capillaries , and subsequent tissue edema . This <a href='uninflect' title='3'><mark>causes</mark></a> overall blood volume loss , with the remaining blood suffering significant plasma loss , making the blood more concentrated . Poor blood flow to organs such as the kidneys and gastrointestinal tract may result in renal failure and stomach ulcers . 
In large burns ( over 30 % of the total body surface area ) , it is a significant inflammatory response . dis result in increased leakage of fluid from da capillaries , and subsequent tissue edema . This cause overall blood volume loss , witt tdaremaining blood suffering significant plasma loss , making the blood more concentrated . Poor blood flow to organs such as the kidneys and gastrointestinal tract may result in renal failure and stomach ulcers .