 The symptomatic ( determinate ) chronic stage affects the nervous system , digestive system and heart . About two @-@ thirds of people with chronic symptoms have cardiac damage , including dilated cardiomyopathy , which causes heart rhythm abnormalities and may result in sudden death . About one @-@ third of patients go on to develop digestive system damage , resulting in dilation of the digestive tract ( megacolon and megaesophagus ) , accompanied by severe weight loss . Swallowing difficulties ( secondary achalasia ) may be the first symptom of digestive disturbances and may lead to malnutrition . 
 The symptomatic ( determinate ) chronic stage <a href='uninflect' title='1'><mark>affects</mark></a> the nervous system , digestive system and heart . About two @-@ thirds of people with chronic symptoms <a href='got' title='2'><mark>have</mark></a> cardiac damage , including dilated cardiomyopathy , which <a href='uninflect' title='3'><mark>causes</mark></a> heart rhythm abnormalities and may result in sudden death . About one @-@ third of patients go on to develop digestive system damage , resulting in dilation of the digestive tract ( megacolon and megaesophagus ) , accompanied by severe weight loss . Swallowing difficulties ( secondary achalasia ) may be the first symptom of digestive disturbances and may lead to malnutrition . 
The symptomatic ( determinate ) chronic stage affect da nervous system , digestive system and heart . About 2 @-@ thirds of niggas w/ chronic symptoms got cardiac damage , including dilated cardiomyopathy , which cause heart rhythm abnormalities and may result in sudden death . About one @-@ third of patients go on to develop digestive system damage , resulting in dilation of tdadigestive tract ( megacolon and megaesophagus ) , accompanied by severe weight loss . Swallowing difficulties ( secondary achalasia ) may be thdairst symptom of digestive disturbances and may lead to malnutrition .