 Antimony @-@ based drugs , such as meglumine antimoniate , are also considered the drugs of choice for treatment of leishmaniasis in domestic animals . Unfortunately , as well as having low therapeutic indices , the drugs are poor at penetrating the bone marrow , where some of the Leishmania amastigotes reside , and so cure of the disease – especially the visceral form – is very difficult . Elemental antimony as an antimony pill was once used as a medicine . It could be reused by others after ingestion and elimination . 
 Antimony @-@ based drugs , such as meglumine antimoniate , are also considered the drugs of choice for treatment of leishmaniasis in domestic animals . Unfortunately , as well as having low therapeutic indices , the drugs <a href='drop_aux' title='1'><mark>are</mark></a>poor at penetrating the bone marrow , where some of the Leishmania amastigotes reside , and so cure of the disease – especially the visceral form – <a href='drop_aux' title='2'><mark>is</mark></a>very difficult . Elemental antimony as an antimony pill was once used as a medicine . It could be reused by others after ingestion and elimination . 
Antimony @-@ based drugs , such as meglumine antimoniate , are also considered the drugs of choice fa treatment of leishmaniasis in domestic animals . Unfortunately , as well as havin low therapeutic indices , the drugs poor at penetrating the bone marrow , where some of da Leishmania amastigotes reside , and so cure of tdadisease – especially thdaisceral form – very difficult . Elemental antimony as an antimony pill was once used as a medicine . It could be reused by others after ingestion and elimination .