 Andrea Bowen , who starred as Susan 's daughter , Julie , departed from the cast , as her character left for college at the end of the fourth season . Teri Hatcher expressed disappointment in the producers ' decision , but Cherry stated that Bowen would return in the future . Joy Lauren , who portrayed Bree 's daughter , Danielle , and Lyndsy Fonseca , who played Katherine 's daughter , Dylan , also left the main cast , although the former appeared in the season premiere as a guest star . Because the fourth season ended leaving Mike 's whereabouts unknown , James Denton 's return to the series was questioned during hiatus . Denton stated in May 2008 that producers would not make a decision on his character until mid @-@ June and that he was preparing to find work in case his contract was terminated . It was later confirmed that he would return to the series . 
 Andrea Bowen , <a href='null_relcl' title='1'><mark>who</mark></a>starred as Susan <a href='null_genetive' title='2'><mark>'s</mark></a>daughter , Julie , departed from the cast , as her character left for college at the end of the fourth season . Teri Hatcher expressed disappointment in the producers <a href='null_genetive' title='3'><mark>'</mark></a>decision , but Cherry stated that Bowen would return in the future . Joy Lauren , <a href='null_relcl' title='4'><mark>who</mark></a>portrayed Bree <a href='null_genetive' title='5'><mark>'s</mark></a>daughter , Danielle , and Lyndsy Fonseca , <a href='null_relcl' title='6'><mark>who</mark></a>played Katherine <a href='null_genetive' title='7'><mark>'s</mark></a>daughter , Dylan , also left the main cast , although the former appeared in the season premiere as a guest star . Because the fourth season ended leaving Mike <a href='null_genetive' title='8'><mark>'s</mark></a>whereabouts unknown , James Denton <a href='null_genetive' title='9'><mark>'s</mark></a>return to the series was questioned during hiatus . Denton stated in May 2008 that producers would not make <a href='None' title='10'><mark>a</mark></a><a href='negative_concord' title='11'><mark>decision</mark></a> on his character until mid @-@ June and that he was preparing to find work in case his contract was terminated . It was later confirmed that he would return to the series . 
Nene Bowen , starred as Susan  daughter , Julie , departed from the cast , as her character left for college at da end of tdafourth season . Teri Hatcher expressed disappointment in the producers  decision , but Cherry stated dat Bowen would return in the future . Joy Lauren , portrayed Bree  daughter , Danielle , and Lyndsy Fonseca , played Katherine  daughter , Dylan , also left thdaain cast , although the former appeared in thedaason premiere as a guest star . cuz the fourth season ended leaving Mike  whereabouts unknown , James Denton  return to the daies was questioned during hiatus . Denton stated in May 2008 tdatproducers would not make no decision on his character till mid @-@ June and that he was preparing to find wrk in case his contract was terminated . It was later confirmed that he would return to the series .