 The application of the Johnson – Corey – Chaykovsky reaction in organic synthesis is diverse . The reaction has come to encompass reactions of many types of sulfur ylides with electrophiles well beyond the original publications . It has seen use in a number of high @-@ profile total syntheses , as detailed below , and is generally recognized as a powerful transformative tool in the organic repertoire . 
 The application of the Johnson – Corey – Chaykovsky reaction in organic synthesis <a href='drop_aux' title='1'><mark>is</mark></a>diverse . The reaction <a href='been_done' title='2'><mark>has</mark></a> come to encompass reactions of many types of sulfur ylides with electrophiles well beyond the original publications . It <a href='been_done' title='3'><mark>has</mark></a> seen use in a number of high @-@ profile total syntheses , as detailed below , and is generally recognized as a powerful transformative tool in the organic repertoire . 
The application of the Johnson – Corey – Chaykovsky reaction in organic synthesis diverse . da reaction done cum to encompass reactions of many types of sulfur ylides wit electrophiles well beyond the original publications . It done seen use in a number of high @-@ profile total syntheses , as detailed below , and is generally recognized as a powerful transformative tool in the organic repertoire .