 The reaction has been used in a number of notable total syntheses including the Danishefsky Taxol total synthesis , which produces the chemotherapeutic drug taxol , and the Kuehne Strychnine total synthesis which produces the pesticide strychnine . 
 The reaction <a href='been_done' title='1'><mark>has</mark></a> been used in a number of notable total syntheses including the Danishefsky Taxol total synthesis , which <a href='uninflect' title='2'><mark>produces</mark></a> the chemotherapeutic drug taxol , and the Kuehne Strychnine total synthesis which <a href='uninflect' title='3'><mark>produces</mark></a> the pesticide strychnine . 
Da reaction done been used in a number of notable total syntheses including tdaDanishefsky Taxol total synthesis , which produce the chemotherapeutic drug taxol , and thdauehne Strychnine total synthesis which produce thedasticide strychnine .