 The toxins in A. muscaria are water @-@ soluble . When sliced thinly , or finely diced and boiled in plentiful water until thoroughly cooked , it seems to be detoxified . Although its consumption as a food has never been widespread , the consumption of detoxified A. muscaria has been practiced in some parts of Europe ( notably by Russian settlers in Siberia ) since at least the 19th century , and likely earlier . The German physician and naturalist Georg Heinrich von Langsdorff wrote the earliest published account on how to detoxify this mushroom in 1823 . In the late 19th century , the French physician Félix Archimède Pouchet was a populariser and advocate of A. muscaria consumption , comparing it to manioc , an important food source in tropical South America that must be detoxified before consumption . 
 The toxins in A. muscaria <a href='drop_aux' title='1'><mark>are</mark></a>water @-@ soluble . When sliced thinly , or finely diced and boiled in plentiful water until thoroughly cooked , it <a href='uninflect' title='2'><mark>seems</mark></a> to be detoxified . Although its consumption as a food <a href='uninflect' title='3'><mark>has</mark></a> <a href='negative_concord' title='4'><mark>never</mark></a> <a href='negative_concord' title='5'><mark>been</mark></a> widespread , the consumption of detoxified A. muscaria <a href='been_done' title='6'><mark>has</mark></a> been practiced in some parts of Europe ( notably by Russian settlers in Siberia ) since at least the 19th century , and likely earlier . The German physician and naturalist Georg Heinrich von Langsdorff wrote the earliest published account on how to detoxify this mushroom in 1823 . In the late 19th century , the French physician Félix Archimède Pouchet was a populariser and advocate of A. muscaria consumption , comparing it to manioc , an important food source in tropical South America <a href='null_relcl' title='7'><mark>that</mark></a>must be detoxified before consumption . 
The toxins in A. muscaria water @-@ soluble . When sliced thinly , or finely diced and boiled in plentiful water until thoroughly cooked , it seem to b detoxified . Although its consumption as a food have never ain't widespread , the consumption of detoxified A. muscaria done been practiced in some parts of Europe ( notably by Russian settlers in Siberia ) since at least da 19th century , and likely earlier . The German physician and naturalist Georg Heinrich von Langsdorff wrote the earliest published account on how to detoxify dis mushroom in 1823 . In tdalate 19th century , the French physician Félix Archimède Pouchet was a populariser and advocate of A. muscaria consumption , comparing it to manioc , an important food source in tropical South America must be detoxified before consumption .