 The Johnson – Corey – Chaykovsky reaction ( sometimes referred to as the Corey – Chaykovsky reaction or CCR ) is a chemical reaction used in organic chemistry for the synthesis of epoxides , aziridines , and cyclopropanes . It was discovered in 1961 by A. William Johnson and developed significantly by E. J. Corey and Michael Chaykovsky . The reaction involves addition of a sulfur ylide to a ketone , aldehyde , imine , or enone to produce the corresponding 3 @-@ membered ring . The reaction is diastereoselective favoring trans substitution in the product regardless of the initial stereochemistry . The synthesis of epoxides via this method serves as an important retrosynthetic alternative to the traditional epoxidation reactions of olefins . 
 The Johnson – Corey – Chaykovsky reaction ( sometimes referred to as the Corey – Chaykovsky reaction or CCR ) <a href='drop_aux' title='1'><mark>is</mark></a>a chemical reaction used in organic chemistry for the synthesis of epoxides , aziridines , and cyclopropanes . It was discovered in 1961 by A. William Johnson and developed significantly by E. J. Corey and Michael Chaykovsky . The reaction <a href='uninflect' title='2'><mark>involves</mark></a> addition of a sulfur ylide to a ketone , aldehyde , imine , or enone to produce the corresponding 3 @-@ membered ring . The reaction <a href='drop_aux' title='3'><mark>is</mark></a>diastereoselective favoring trans substitution in the product regardless of the initial stereochemistry . The synthesis of epoxides via this method <a href='uninflect' title='4'><mark>serves</mark></a> as an important retrosynthetic alternative to the traditional epoxidation reactions of olefins . 
The Johnson – Corey – Chaykovsky reaction ( sometimes referred to as the Corey – Chaykovsky reaction or CCR ) a chemical reaction used in organic chemistry fir da synthesis of epoxides , aziridines , and cyclopropanes . It was discovered in 1961 by A. William Johnson and developed significantly by E. J. Corey and Michael Chaykovsky . The reaction involve addition of a sulfur ylide to a ketone , aldehyde , imine , or enone to produce tdacorresponding 3 @-@ membered ring . The reaction diastereoselective favoring trans substitution in thdaroduct regardless of the initial stereochemistry . Thedanthesis of epoxides via dis method serve as an important retrosynthetic alternative to the daditional epoxidation reactions of olefins .