 The victims of this poisoning were almost exclusively post @-@ menopausal women with low iron and other mineral body stores . Similar general population cadmium exposures in other parts of the world have not resulted in the same health problems because the populations maintained sufficient iron and other mineral levels . Thus , although cadmium is a major factor in the itai @-@ itai disease in Japan , most researchers have concluded that it was one of several factors . Cadmium is one of six substances banned by the European Union 's Restriction on Hazardous Substances ( RoHS ) directive , which regulates hazardous substances in electrical and electronic equipment but allows for certain exemptions and exclusions from the scope of the law . The International Agency for Research on Cancer has classified cadmium and cadmium compounds as carcinogenic to humans . Although occupational exposure to cadmium is linked to lung and prostate cancer , there is still a substantial controversy about the carcinogenicity of cadmium in low environmental exposure . Recent data from epidemiological studies suggest that intake of cadmium through diet associates to higher risk of endometrial , breast and prostate cancer as well as to osteoporosis in humans . A recent study has demonstrated that endometrial tissue is characterized by higher levels of cadmium in current and former smoking females . 
 The victims of this poisoning <a href='uninflect' title='1'><mark>were</mark></a> almost exclusively post @-@ menopausal women with low iron and other mineral body stores . Similar general population cadmium exposures in other parts of the world <a href='been_done' title='2'><mark>have</mark></a> not resulted in the same health problems because the populations maintained sufficient iron and other mineral levels . Thus , although cadmium <a href='drop_aux' title='3'><mark>is</mark></a>a major factor in the itai @-@ itai disease in Japan , most researchers <a href='been_done' title='4'><mark>have</mark></a> concluded that it was one of several factors . Cadmium <a href='drop_aux' title='5'><mark>is</mark></a>one of six substances banned by the European Union <a href='null_genetive' title='6'><mark>'s</mark></a>Restriction on Hazardous Substances ( RoHS ) directive , which <a href='uninflect' title='7'><mark>regulates</mark></a> hazardous substances in electrical and electronic equipment but <a href='uninflect' title='8'><mark>allows</mark></a> for certain exemptions and exclusions from the scope of the law . The International Agency for Research on Cancer <a href='been_done' title='9'><mark>has</mark></a> classified cadmium and cadmium compounds as carcinogenic to humans . Although occupational exposure to cadmium is linked to lung and prostate cancer , <a href='dey_it' title='10'><mark>there</mark></a> is still a substantial controversy about the carcinogenicity of cadmium in low environmental exposure . Recent data from epidemiological studies suggest that intake of cadmium through diet associates to higher risk of endometrial , breast and prostate cancer as well as to osteoporosis in humans . A recent study <a href='been_done' title='11'><mark>has</mark></a> demonstrated that endometrial tissue is characterized by higher levels of cadmium in current and former smoking females . 
The victims of this poisoning was almost exclusively post @-@ menopausal women witt low iron and other mineral body stores . Similar general population cadmium exposures in other parts of da world done not resulted in the same health problems because the populations maintained sufficient iron and other mineral levels . Thus , although cadmium a major factor in tdaitai @-@ itai disease in Japan , most researchers done concluded dat it was one of several factors . Cadmium one of six substances banned by thdauropean Union  Restriction on Hazardous Substances ( RoHS ) directive , which regulate hazardous substances in electrical and electronic equipment but allow for certain exemptions and exclusions from the scope of thedaw . The daernational Agency for Research on Cancer done classified cadmium and cadmium compounds as carcinogenic to humans . Although occupational exposure to cadmium is linked to lung and prostate cancer , it is still a substantial controversy about the cdainogenicity of cadmium in low environmental exposure . Recent data from epidemiological studies suggest that intake of cadmium through diet associates to higher risk of endometrial , breast and prostate cancer as well as to osteoporosis in humans . A recent study done demonstrated tdatendometrial tissue is characterized by higher levels of cadmium in current and former smoken females .