The often-deadly story lines on Grey's Anatomy mean that the cast rotates out on the regular. With season 13 returning for its winter premiere on January 26, it's time we remember all of the main characters we've bid farewell to on the series. While not everyone who has left the show has done so in a body bag, they've all done so after some serious drama. Whether it was a breakup or car accident that made them peace out of Grace-Sloan Memorial, we'll never forget the tears we cried at their expense.