And here she is today, working on what is sure to be a momentous speech. Seth Meyers has hinted that tonight's show will address the reckoning currently taking place in Hollywood over issues of sexual harassment and assault, and perhaps Oprah will use this opportunity to weigh in. "This is what I do know for sure: When something this major happens, when you have the fallout, 50 women coming forward, that it's a watershed moment," she said about the allegations against Harvey Weinstein on CBS This Morning back in October . "And what I do believe is actually happening is that, first of all, it's triggering a lot of unreleased pain, repressed anger, guilt and suffering that a lot of women have had."