How much of this episode is based on real events?

Francesca Delbanco: "A lot of it is based on things that actually happened. We had our first child very easily, without any kind of fertility issues. Then we kind of got mired in just terrible, terrible luck. We had a really tough time having a second child, which was something we really wanted to do. I had three miscarriages; we had to terminate a pregnancy in the second trimester, because we had done genetic testing that came back with bad news. We had every manner of problems, so we decided to do IVF. We did IVF, and it was an ordeal in and of itself, as it is for anyone who has to do it. It was ultimately successful — we have three children now. But when we were doing IVF, we had what happens on episode 104, which is that Nick —"