But that's not all "There is some evidence to suggest that stress can lower the threshold for a flare-up," Dr. Kluk says. "Other triggers include extremes of weather, being unwell, and being around certain pets, dust, and wool clothing." But the way eczema manifests is generally similar for everyone. "The main symptom is itching and dry and red skin," she says. "When eczema is very active, it may become moist, crusted, or weepy, especially on the hands and feet, but it can affect any part of the skin, including the face and eyelids. Areas that are most commonly affected are the creases of the elbows and knees, as well as the wrists, ankles and neck."