Congenital long QT syndrome is a hereditary rhythm disorder of autosomal dominant transmission which predisposes to sudden death in childhood and which can be the subject of preventive treatment. this pathology is very heterogeneous on the genetic level. what is(are) the correct proposition(s):
The genes involved encode ion channels
Long QT syndrome is most often associated with a congenital heart defect
The genetic evaluation of this pathology is done by the study of the karyotype
The diagnosis in an index case must lead to information for relatives
Molecular predictive diagnosis is not authorized in minor children in this situation