A 52-year-old patient with no particular history presents high blood pressure, proteinuria of 2 g/24 hours, hematuria of 105 red blood cells/ml with serum creatinine of 130 µmol/l. his vesico-renal ultrasound is normal. here is the report of his kidney biopsy: cortical fragment comprising 15 glomeruli including 4 sclerotic glomeruli. Permeable glomeruli exhibit mesangial and endocapillary proliferation. lesions of moderate arteriolosclerosis. lesions of tubular atrophy and interstitial fibrosis on approximately 20% of the parenchyma. immunofluorescence finds deposits of Iga to +++ in the mesangium and of c3 to 1+ in the vessels and glomeruli. what is(are) the possible diagnosis(es)?
Tubulointerstitial nephropathy
Lupus nephropathy class IV
Pauci-immune glomerulonephritis
Iga nephropathy
Nephroangiosclerosis