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|---|---|---|---|---|
O=C(NCCc1ccccc1)c1ccc2c(c1)N(Cc1ccc(F)cc1)C(=O)c1ccccc1S2 | NCGC00140539-01 | 18 | 6.1098 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
O=C(NCCN1CCCC1)c1ccc2c(c1)N(Cc1ccc(F)cc1)C(=O)c1ccccc1[S+]2[O-] | MLS000117750-01 | 18 | 3.9784 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
O=C(NCCc1ccc(Cl)cc1)c1ccc2c(c1)N(Cc1ccc(Cl)cc1)C(=O)CS2 | NCGC00104156-01 | 18 | 5.6048 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
O=C(NCCc1ccccc1)c1ccc2c(c1)N(Cc1ccc(Cl)cc1)C(=O)CS2 | NCGC00104160-01 | 18 | 4.9514 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
O=C(NCCc1ccc(Cl)cc1)c1ccc2c(c1)N(Cc1c(F)cccc1Cl)C(=O)CS2 | NCGC00104190-01 | 18 | 5.7439 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
O=C(NCCc1ccccc1)c1ccc2c(c1)N(Cc1c(F)cccc1Cl)C(=O)CS2 | NCGC00104210-01 | 18 | 5.0905 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
CCCC1=Nc2cc(C(=O)NCCc3ccccc3)ccc2Sc2ccc(C)cc21 | NCGC00107615-01 | 18 | 6.353 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
COc1cccc(CN2C(=O)c3ccccc3Sc3ccc(C(=O)NCCc4ccc(C)cc4)cc32)c1 | NCGC00108122-01 | 18 | 6.2877 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
COc1cccc(CN2C(=O)c3ccccc3Sc3ccc(C(=O)NCc4ccccc4)cc32)c1 | NCGC00108124-01 | 18 | 5.9368 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
O=C(NCc1ccco1)c1ccc2c(c1)N(Cc1c(F)cccc1Cl)C(=O)c1ccccc1S2 | NCGC00108150-01 | 18 | 6.3137 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
CCOc1ccc(CN2C(=O)c3ccccc3Sc3ccc(C(=O)NCCc4ccccc4)cc32)cc1 | NCGC00108212-01 | 18 | 6.3694 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
O=C(NC1CCCC1)c1ccc2c(c1)N(Cc1ccc(C(F)(F)F)cc1)C(=O)c1ccccc1S2 | NCGC00108220-01 | 18 | 6.6894 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
Cc1ccc(CCNC(=O)c2ccc3c(c2)N(Cc2cccc(C)c2)C(=O)c2ccccc2S3(=O)=O)cc1 | NCGC00109476-01 | 18 | 5.2691 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
O=C(NCCc1ccccc1)c1ccc2c(c1)N(Cc1ccc(Cl)cc1)C(=O)c1ccccc1S2(=O)=O | NCGC00109546-01 | 18 | 5.3057 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
O=C(NCCc1ccccc1)c1ccc2c(c1)N(Cc1ccccc1F)C(=O)c1ccccc1[S+]2[O-] | NCGC00109588-01 | 18 | 5.1253 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
O=C(NCCc1ccc(Cl)cc1)c1ccc2c(c1)N(Cc1ccccc1F)C(=O)c1ccccc1S2(=O)=O | NCGC00109614-01 | 18 | 5.4448 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
O=C(NCCC1=CCCCC1)c1ccc2c(c1)N(Cc1ccc(F)cc1)C(=O)c1ccccc1S2(=O)=O | NCGC00109709-01 | 18 | 5.4392 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
O=C(NCc1ccccc1)c1ccc2c(c1)N(Cc1ccccc1)C(=O)c1ccccc1S2(=O)=O | NCGC00109861-01 | 18 | 4.6098 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
Cc1ccc(CNC(=O)c2ccc3c(c2)N(Cc2ccccc2)C(=O)c2ccccc2S3(=O)=O)cc1 | NCGC00109871-01 | 18 | 4.9182 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
O=C(NCCC1=CCCCC1)c1ccc2c(c1)N(Cc1ccccc1)C(=O)c1ccccc1S2(=O)=O | NCGC00109891-01 | 18 | 5.3001 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
O=C(Nc1cccc(F)c1)c1ccc2c(c1)N(Cc1ccccc1)C(=O)c1ccccc1S2(=O)=O | NCGC00111854-01 | 18 | 5.0712 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
CC(C)CCNC(=O)Nc1ccc2c(c1)N(Cc1ccccc1)C(=O)c1ccccc1S2 | NCGC00113731-01 | 18 | 6.1658 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
O=C(OCc1ccco1)c1ccc2c(c1)N(Cc1cccc(F)c1)C(=O)c1ccccc1S2 | NCGC00131999-01 | 18 | 6.0873 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
O=C(Nc1ccc2c(c1)N(C1CCCC1)C(=O)c1ccccc1S2)c1ccc(F)cc1 | NCGC00138155-01 | 18 | 6.132 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
Cc1ccc(CN2C(=O)c3ccccc3Sc3ccc(C(=O)NCc4ccco4)cc32)cc1 | NCGC00139720-01 | 18 | 5.8296 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
Cc1ccc(CN2C(=O)c3ccccc3Sc3ccc(C(=O)NC4CCCCC4)cc32)cc1 | NCGC00139722-01 | 18 | 6.3691 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
Cc1cccc(CN2C(=O)c3ccccc3Sc3ccc(C(=O)NCCc4ccccc4)cc32)c1 | NCGC00139852-01 | 18 | 6.2791 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
Cc1cccc(CN2C(=O)c3ccccc3Sc3ccc(C(=O)NCc4ccco4)cc32)c1 | NCGC00139854-01 | 18 | 5.8296 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
Cc1cccc(CN2C(=O)c3ccccc3Sc3ccc(C(=O)NCc4cccs4)cc32)c1 | NCGC00139856-01 | 18 | 6.2981 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
O=C(NC1CCCC1)c1ccc2c(c1)N(Cc1ccccc1)C(=O)c1ccccc1S2 | NCGC00139858-01 | 18 | 5.6706 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
O=C(NCc1ccco1)c1ccc2c(c1)N(Cc1ccccc1)C(=O)c1ccccc1S2 | NCGC00139880-01 | 18 | 5.5212 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
O=C(NCCc1ccc(Cl)cc1)c1ccc2c(c1)N(Cc1ccc(F)cc1)C(=O)CS2 | NCGC00139944-01 | 18 | 5.0905 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
O=C(NCc1ccco1)c1ccc2c(c1)N(Cc1ccc(Cl)cc1)C(=O)c1ccccc1S2 | NCGC00140009-01 | 18 | 6.1746 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
COc1ccc(CCNC(=O)c2ccc3c(c2)N(Cc2ccc(Cl)cc2)C(=O)c2ccccc2S3)cc1OC | NCGC00140011-01 | 18 | 6.6413 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
CC(C)CCNC(=O)c1ccc2c(c1)N(Cc1cccc(Cl)c1)C(=O)c1ccccc1S2 | NCGC00140015-01 | 18 | 6.4275 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
Cc1ccc(C)c(CN2C(=O)c3ccccc3Sc3ccc(C(=O)NCc4ccco4)cc32)c1 | NCGC00140040-01 | 18 | 6.138 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
Cc1ccc(C)c(CN2C(=O)c3ccccc3Sc3ccc(C(=O)NCc4cccs4)cc32)c1 | NCGC00140046-01 | 18 | 6.6065 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
Cc1ccccc1CN1C(=O)c2ccccc2Sc2ccc(C(=O)NCCc3ccccc3)cc21 | NCGC00140200-01 | 18 | 6.2791 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
Cc1ccccc1CN1C(=O)c2ccccc2Sc2ccc(C(=O)NC(C)c3ccccc3)cc21 | NCGC00140204-01 | 18 | 6.7976 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
Cc1ccccc1CN1C(=O)c2ccccc2Sc2ccc(C(=O)NCc3cccs3)cc21 | NCGC00140208-01 | 18 | 6.2981 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
O=C(NCc1cccs1)c1ccc2c(c1)N(Cc1ccccc1Cl)C(=O)c1ccccc1S2 | NCGC00140369-01 | 18 | 6.6431 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
CC1CCC(NC(=O)c2ccc3c(c2)N(Cc2ccccc2F)C(=O)c2ccccc2S3)CC1 | NCGC00140371-01 | 18 | 6.4458 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
O=C(NC1CCCC1)c1ccc2c(c1)N(Cc1ccccc1Cl)C(=O)c1ccccc1S2 | NCGC00140449-01 | 18 | 6.324 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
O=C(NCCc1ccccc1)c1ccc2c(c1)N(Cc1ccccc1Cl)C(=O)c1ccccc1S2 | NCGC00140481-01 | 18 | 6.6241 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
COc1ccc(CCNC(=O)c2ccc3c(c2)N(Cc2ccccc2Cl)C(=O)c2ccccc2S3)cc1OC | NCGC00140483-01 | 18 | 6.6413 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
CN(Cc1ccccc1)C(=O)c1ccc2c(c1)N(Cc1ccccc1Cl)C(=O)c1ccccc1S2 | NCGC00140485-01 | 18 | 6.9238 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
O=C(NCc1cccs1)c1ccc2c(c1)N(Cc1cccc(F)c1)C(=O)c1ccccc1S2 | NCGC00140499-01 | 18 | 6.1288 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
O=C(NCc1ccc2c(c1)OCO2)c1ccc2c(c1)N(Cc1ccccc1F)C(=O)c1ccccc1S2 | NCGC00140511-01 | 18 | 5.796 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
CN(C(=O)c1ccc2c(c1)N(Cc1ccccc1F)C(=O)c1ccccc1S2)C1CCCCC1 | NCGC00140513-01 | 18 | 6.542 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
O=C(NC1CCCC1)c1ccc2c(c1)N(Cc1ccccc1F)C(=O)c1ccccc1S2 | NCGC00140515-01 | 18 | 5.8097 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
O=C(NC1CCCCC1)c1ccc2c(c1)N(Cc1ccccc1F)C(=O)c1ccccc1S2 | NCGC00140517-01 | 18 | 6.1998 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
CC1CCC(NC(=O)c2ccc3c(c2)N(Cc2cccc(F)c2)C(=O)c2ccccc2S3)CC1 | NCGC00140519-01 | 18 | 6.4458 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
CC(NC(=O)c1ccc2c(c1)N(Cc1cccc(F)c1)C(=O)c1ccccc1S2)c1ccccc1 | NCGC00140523-01 | 18 | 6.6283 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
Cc1ccc(CCNC(=O)c2ccc3c(c2)N(Cc2cccc(F)c2)C(=O)c2ccccc2S3)cc1 | NCGC00140529-01 | 18 | 6.4182 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
O=C(NCc1ccccc1)c1ccc2c(c1)N(Cc1cccc(Cl)c1)C(=O)c1ccccc1S2(=O)=O | NCGC00140560-01 | 18 | 5.2632 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
Cc1ccc(CCNC(=O)c2ccc3c(c2)N(Cc2cccc(Cl)c2)C(=O)c2ccccc2S3(=O)=O)cc1 | NCGC00140562-01 | 18 | 5.6141 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
O=C(NC1CCCC1)c1ccc2c(c1)N(Cc1ccc(F)cc1)C(=O)c1ccccc1S2 | NCGC00140635-01 | 18 | 5.8097 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
O=C(NCCC1=CCCCC1)c1ccc2c(c1)N(Cc1cccc(Cl)c1)C(=O)c1ccccc1S2(=O)=O | NCGC00140654-01 | 18 | 5.9535 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
COc1ccc(-n2c(SCC(=O)Nc3ccc4c(c3)OCO4)nc3ccccc3c2=O)cc1 | MLS000078493-01 | 18 | 3.8538 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
COc1cccc(-n2nc(C(=O)Nc3ccc4c(c3)OCO4)c3ccccc3c2=O)c1 | MLS000047554-01 | 18 | 3.3753 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
O=C(CSc1nnc(Cc2cccs2)n1-c1ccccc1)Nc1ccc2c(c1)OCCO2 | MLS000050951-01 | 18 | 4.4216 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
COc1ccc(-c2noc(CSc3nc4ccccc4c(=O)n3-c3ccccc3)n2)cc1 | MLS000051825-01 | 18 | 4.7366 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
Cc1cc(C(=O)CSc2nc3ccccc3c(=O)n2C)c(C)n1Cc1ccc2c(c1)OCO2 | MLS000056325-01 | 18 | 4.1038 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
COc1ccc(-n2nnnc2SCC(=O)Nc2ccccc2)cc1 | MLS000067810-01 | 18 | 2.4017 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
COc1ccc(-n2nnc3c(SCC(=O)Nc4ccc5c(c4)OCCO5)ncnc32)cc1 | MLS000094060-01 | 18 | 2.7211 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
COc1ccc(NC(=O)CSc2nc3ccccc3c(=O)n2-c2ccc3c(c2)OCO3)c(OC)c1 | MLS000095260-01 | 18 | 3.8624 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
CCOc1ccc(-n2c(SCC(=O)Nc3ccc4c(c3)OCO4)nc3c(c2=O)SCC3)cc1 | MLS000101291-01 | 18 | 3.7389 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
O=C(CSc1nc2c(c(=O)n1-c1ccc(Cl)cc1)SCC2)Nc1ccc2c(c1)OCCO2 | MLS000101300-01 | 18 | 4.0361 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
CC1Cc2nc(SCC(=O)Nc3ccc4c(c3)OCO4)n(CCc3ccccc3)c(=O)c2S1 | MLS000101671-01 | 18 | 3.9822 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
COc1ccc2[nH]c3nc(SCC(=O)Nc4ccc5c(c4)OCO5)nnc3c2c1 | MLS000121584-01 | 18 | 2.9742 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
COc1cccc(-n2c(SCC(=O)Nc3ccc4c(c3)CCC4)nc3ccccc3c2=O)c1 | MLS000334092-01 | 18 | 4.6138 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
Cc1cc(C)cc(-n2c(SCC(=O)NCc3ccc4c(c3)OCO4)nc3ccccc3c2=O)c1 | MLS000334222-01 | 18 | 4.1397 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
O=C(CSc1nc2ccccc2c(=O)n1-c1ccccc1F)Nc1ccc2c(c1)CCC2 | MLS000334406-01 | 18 | 4.7443 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
O=C(CSc1nc2ccccc2c(=O)n1-c1ccc(F)cc1F)Nc1ccc2c(c1)CCC2 | MLS000334407-01 | 18 | 4.8834 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
O=C(CSc1nc2ccccc2c(=O)n1-c1ccc(F)cc1)Nc1ccc2c(c1)CCC2 | MLS000334435-01 | 18 | 4.7443 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
O=C(CSc1nc2ccccc2c(=O)n1-c1ccc(F)c(Cl)c1)Nc1cccc(S(=O)(=O)N2CCOCC2)c1 | MLS000339538-01 | 18 | 3.9299 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
COc1ccccc1-n1c(SCC(=O)NCc2ccc3c(c2)OCO3)nc2cc([N+](=O)[O-])ccc21 | MLS000388903-01 | 18 | 4.0795 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
COc1cccc(-n2c(SCC(=O)c3c[nH]c4ccccc34)nc3ccccc3c2=O)c1 | MLS000391110-01 | 18 | 4.8506 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
O=C(COC(=O)c1cc(-c2ccccc2)nc2ccccc12)Nc1ccc2c(c1)OCO2 | MLS000391595-01 | 18 | 4.426 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
Cc1ccc(-n2c(SCC(=O)Nc3cc(S(=O)(=O)N4CCOCC4)ccc3Cl)nc3ccccc3c2=O)cc1 | MLS000393196-01 | 18 | 4.0992 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
O=C(CSc1nc2ccccc2c(=O)n1-c1ccccc1Cl)Nc1cccc(S(=O)(=O)N2CCOCC2)c1 | MLS000393811-01 | 18 | 3.7908 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
CCc1ccc(-n2c(SCC(=O)Nc3cccc(S(=O)(=O)NC4=NCCCCC4)c3)nc3ccccc3c2=O)cc1 | MLS000393996-01 | 18 | 4.9297 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
O=C(CSc1nc2ccccc2c(=O)n1-c1ccc(F)cc1)Nc1cc(S(=O)(=O)N2CCOCC2)ccc1Cl | MLS000402281-01 | 18 | 3.9299 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
O=C(CSc1nc2ccccc2c(=O)n1-c1ccc(F)cc1)Nc1ccc(Cl)c(S(=O)(=O)N2CCOCC2)c1 | MLS000418653-01 | 18 | 3.9299 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
Cc1ccc(-n2c(SCC(=O)Nc3cccc(C)c3)nc3c(oc4ccccc43)c2=O)cc1 | MLS000418803-01 | 18 | 5.4795 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
COc1ccc(C(=O)Nn2c(SCC(=O)c3ccccc3)nc3ccccc3c2=O)cc1 | MLS000520798-01 | 18 | 3.764 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
CCOc1ccc(-n2c(SCC(=O)Nc3ccc4c(c3)OCO4)nc3ccccc3c2=O)cc1 | MLS000555990-01 | 18 | 4.2439 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
COc1ccc(NC(=O)CSc2nc3ccccc3cc2Cc2ccccc2)cc1 | MLS000556057-01 | 18 | 5.565 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
O=C(CSc1nc(Cc2ccccc2)nc2ccccc12)Nc1ccc2c(c1)OCCO2 | MLS000556790-01 | 18 | 4.7226 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
COC(=O)c1ccc(CSc2nc3ccccc3c(=O)n2-c2ccccc2)o1 | MLS000566237-01 | 18 | 4.0576 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
Cc1cc(C)cc(-n2c(SCC(=O)NCc3ccco3)nc3ccccc3c2=O)c1 | MLS000566294-01 | 18 | 4.004 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
COc1ccc(-c2cc(C(F)(F)F)nc(SCC(=O)Nc3ccc4c(c3)OCO4)n2)cc1 | MLS000569426-01 | 18 | 4.6305 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
O=C(CSc1nc2ccccc2c(=O)n1-c1ccccc1)N1CCc2ccccc21 | MLS000579939-01 | 18 | 4.0671 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
COc1cccc(NC(=O)CSc2nc3ccccc3c3nc4ccccc4n23)c1 | MLS000583513-01 | 18 | 4.7751 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
COc1cccc(NC(=O)CSc2nc3ccccc3c(=O)n2Cc2cccs2)c1 | MLS000583550-01 | 18 | 4.2457 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
COc1ccc(-c2nsc(SCC(=O)Nc3ccc4c(c3)OCO4)n2)cc1 | MLS000720375-01 | 18 | 3.6732 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
Cc1cccc(NC(=O)CSc2nc3c(oc4ccccc43)c(=O)n2-c2ccccc2)c1 | MLS000722143-01 | 18 | 5.1711 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
Cc1cc(C)cc(NC(=O)CSc2nc3c(oc4ccccc43)c(=O)n2-c2ccccc2)c1 | MLS000722153-01 | 18 | 5.4795 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
Cc1cccc(-c2nc(SCC(=O)Nc3ccc4c(c3)OCO4)c(-c3ccccc3)[nH]2)c1 | NCGC00107650-01 | 18 | 5.5116 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |
COc1cccc(-c2nc(SCC(=O)Nc3ccc4c(c3)OCO4)c(-c3ccccc3)[nH]2)c1 | NCGC00107654-01 | 18 | 5.2118 | Ferriera RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ and Shoichet BK, J Med Chem, 2010, 53, 4891-905. |