“We think that we now have enough understanding of the mechanism that we have our foot in the door to explore the relevance of this biology more broadly,” said Cate.
Co-authors of the paper are Cate, Doudna and postdoctoral scholar Nathanael Lintner of UC Berkeley and Pfizer researchers Kim McClure, Donna Petersen, Allyn Londregan, David Piotrowski, Liuqing Wei, Jun Xiao, Michael Bolt, Paula Loria, Bruce Maguire, Kieran Geoghegan, Austin Huang, Tim Rolph and Spiros Liras.
The work was funded by Pfizer, with computing and gene sequencing assistance through resources supported by the National Institutes of Health.