oat, difficulty breathing, severe itching of your skin with
raised lumps, joint pain, sensitivity to the sun, general feeling of
being unwell. You may need urgent medical attention.
Some patients may experience a severe reaction to high
levels of thyroid hormone. This is called a “thyroid crisis” and
you should contact your doctor immediately if you have any
of the following symptoms:
• very high temperature; fast heart rate; irregular heartbeat; low
blood pressure; heart failure; jaundice; confusion; fits and coma.
Tell your doctor or pharmacist if any of the following side
effects continue, get worse or if you notice any other side
effects not listed.
Most of the side effects are similar to the symptoms of
hyperthyroidism (where the thyroid gland makes too much thyroxine)
and are due to your dose of the medicine being too high. They will
usually disappear after reducing the dose or stopping the tablets.
However, you must not change the dose or stop the tablets
without talking to your doctor first.
Not known (frequency cannot be estimated from the available
• high temperature, sweating
• weight loss
• tremor, restlessness, excitability, difficulty sleeping (insomnia)
• increased pressure around the brain in children that is not caused
by a tumour or other diseases (benign intracranial hypertension)
• chest pain (angina), pounding, irregular or fast heartbeat
• diarrhoea, vomiting
• muscle cramps, muscle weakness
• deformity of the skull in infants caused by the early closure of
joints in the skull bone (craniostenosis)
• growth in children may slow or stop due to changes in bone
• irregular periods
• intolerance to heat
• temporary hair loss in children.
Reporting of side effects:
If you get any side effects, talk to your doctor, pharmacist or nurse.
This includes any possible side effects not listed in this leaflet. You
can also report side effects directly via the Yellow Card Scheme at:
By reporting side effects you can help provide more information on
the safety of this medicine.
5. HOW TO STORE LEVOTHYROXINE TABLETS
Keep this medicine out of the sight and reach of children.
Do not use this medicine after the expiry date which is stated on the
carton after EXP. The expiry date refers to the last day of that month.
Do not store above 25°C. Store in the original package in order to
protect from light and moisture.
Do not throw away any medicine via wastewater or household waste.
Ask your pharmacist how to throw away medicines you no longer
use. These measures will help protect the environment.
6. Contents of the pack and other information
What Levothyroxine Tablets contain:
- The active substance is anhydrous levothyroxine sodium. This
leaflet concerns two strengths of Levothyroxine tablets. Each
strength contains respectively 50 and 100 micrograms of
anhydrous levothyroxine sodium.
- The other ingredients are sodium citrate, lactose, maize starch,
acacia powder and magnesium stearate.
What Levothyroxine Tablets look like and contents of the
Each tablet is scored on one side and engraved on the other with
50mcg – FW21
100mcg – FW31.
They are packed in a blister pack of 28, 56 or 112 tablets and
polypropylene containers of 28, 56, 100, 112 or 1000 tablets. Not all
pack sizes may be marketed.
Marketing Authorisation Holder:
Mercury Pharma (Generics) Ltd., Capital House, 85 King William
Street, London, EC4N 7BL, UK
Custom Pharmaceuticals Ltd., Tecore House, Conway Street,
Hove, East Sussex, BN3 3LW, UK
This leaflet was last revised in September 2016.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.