 with Klinefelter’s syndrome should therefore have regular check-ups during adult life, ideally in a specialist endocrinology clinic, both to monitor their general health and particularly to monitor testosterone replacement therapy.
Fertility problems are common in men with Klinefelter’s syndrome. However, more recent specialised fertility techniques such as microsurgical testicular sperm extraction and intracytoplasmic sperm injection have helped some men with Klinefelter’s syndrome to father children. If patients have any concerns, they should discuss them with their doctor.
Reviewed: December 2014