A gene with a level of expression that varies cyclically, and which might therefore be involved in the generation of biological rhythyms. Examples: period, timeless.
One of the two main hypotheses advanced to explain the absence of autoimmune responses: now generally accepted. Clonal deletion is the programmed death of inappropriately ...
The process whereby one or more clones, ie. cells expressing a particular gene sequence are selected by naturally-occurring processes from a mixed population. Generally the ...
A propagating population of organisms, either single cell or multicellular, derived from a single progenitor cell. Such organisms should be genetically identical, though ...
Centrally-acting anti-hypertensive agent that works by inhibiting activity of the sympathoexcitatory neurons that regulate arterial pressure. Considered to be a mixed agonist ...
The process whereby clones are established. The term covers various manipulations for isolating and establishing clones: in simple systems single cells may be isolated without ...
A plasmid vector that can be used to transfer DNA from one cell type to another. Cloning vectors are usually designed to have convenient restriction sites that can be cut to ...
Chinese liver fluke. Can infect man if inadequately cooked fish is eaten and can cause biliary obstruction as a result of liver infestation.
Genus of Gram positive anaerobic spore-forming bacilli commonly found in soil. Many species produce exotoxins of great potency, the best known being C. botulinum, and C. ...
Clostridium difficile toxins
C. difficile enterotoxin A (308 kD) is secreted, enters eukaryotic cell by receptor-mediated endocytosis and once in cytoplasm glucosylates small G-proteins of rho family ...
Vertebrate glycoprotein of uncertain function. Secreted as a 400 amino acid peptide, then cleaved to form two 200 amino acid peptides that are linked by a disulphide bridge. ...
Of acetylcholine receptors: aggregation of the receptors in developing myotubes in the vicinity of the presynaptic terminal, induced by nerve contact. See agrin.
Chick homologue of myoD.
(1) Cell-mediated lympholysis: the process of target cell lysis by CMCs.
(2) Chronic myeloid leukaemia.
See cytotoxic necrotising factors.
Diverse Phylum of diploblastic animals that includes Classes Hydrozoa (freshwater polyps, small jellyfish), Scyphozoa (large jellyfish), and Anthozoa (sea ...
Ectodermal cell of Cnidaria (coelenterates) specialized for defence or capturing prey. Each cell has a nematocyst that can be replaced once discharged.
Process whereby a protein is moved across a membrane as it is being synthesized. This process occurs during the translation of the message at membrane-associated ribosomes in ...
In membrane transport describes tight coupling of the transport of one species (generally Na+) to another (eg. a sugar or amino acid). The transport of Na+ from high to low ...
Colloidal aggregation containing a mixture of organic compounds. One theory of the evolution of life is that the formation of coacervates in the primaeval soup was a step ...
First stage in the formation of a coated vesicle.
Vesicle formed as an invagination of the plasma membrane (a coated pit), and that is surrounded by a basket of clathrin. Associated with receptor-mediated pinocytosis and ...
Polypeptide toxin (71 residues) from Naja kaouthia. One of the alpha-neurotoxins (curaremimetics), it binds to nicotinic acetylcholine receptors with high ...
Drug of abuse and psychostimulant that acts to increase extra-neuronal dopamine in midbrain by binding to the dopamine uptake transporter and hence inhibiting dopamine ...
Bacteria with a spherical shape.
cochlear hair cell
The sound-sensing cell of the inner ear. The cells have modified ciliary structures (hairs), that enable them to produce an electrical (neural) response to mechanical motion ...
Genes in which both alleles of a pair are fully expressed in the heterozygote as, for example, AB blood group in which both A and B antigens are present.
The coding unit of DNA that specifies the function of the corr