l 2003; Prasad SB et al 1992). Vitamin E supplements boost the function of immune cells capable of killing lymphoma cells (Ashfaq MK et al 2000; Dalen H et al 2003b; Dasgupta J et al 1993). Alpha-tocopheryl succinate, a semisynthetic analogue of vitamin E, is a potential adjuvant in cancer treatment (Dalen H et al 2003a).
Calorie Restriction Mimetic Formula
Scientists have intensely focused on finding out how calorie restriction so radically extends life span. In response to reduced calorie intake, beneficial “youth” genes are activated while detrimental “senescence” genes are disabled. These favorable gene expression changes play a critical role in the ability of calorie restriction to slow aging.
The good news is that a select group of nutrients has been discovered that trigger many of the same favorable mechanisms (including more youthful gene expression patterns) as caloric restriction. Among the most promising caloric restriction mimics and enhancers are resveratrol, pterostilbene, quercetin, and grape seed polyphenols, along with black tea extract. These nutrients have been shown to generate many of the same effects in the body as caloric restriction, without significant dietary modification.
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