novel 'Fish and Chips' device can be used as the first step in drug screening during the preclinical phase to complement existing animal models and improve toxicity testing. The design of our platform can also be modified to accommodate more zebrafish embryos, as well as the embryos of other animal models. Our next step will involve investigating cardiotoxicity and hepatoxicity on the chip."
"Miniaturization is being explored in various ways by our researchers to revolutionize drug development and disease diagnosis. This latest microfluidic platform developed by IBN enables researchers to cut down the time and cost of drug testing significantly. Our technology is available for licensing to companies, and we are also open to collaboration to develop customized assays for drug testing," added Professor Jackie. Y. Ying, IBN Executive Director.
This multi-channel microfluidic perfusion platform was developed in collaboration with Dr Danny van Noort of the MechanoBiology Institute, Singapore, who provided guidance on chip design and Associate Professor Vladimir Korzh's group at the Institute of Molecular and Cell Biology, who provided the transgenic zebrafish lines and fish culture expertise.