 stomach.
They are used to treat heartburn and ulcers. They're also used to heal damage in the esophagus caused by stomach acid.
PPIs are better at treating heartburn than H2 blockers, but they do not relieve heartburn right away.
- Most PPIs are available over the counter, but a few still require a prescription.
- |Aspirin, sodium bicarbonate, and citric aci - Alka-Seltzer™
- Calcium carbonate - Tums™
- Aluminum hydroxide and magnesium hydroxide - Maalox™
- Calcium carbonate and magnesium hydroxide - Rolaids™
Antacids can affect how other medicines work. It is best to take the medicines listed below about 2 hours before or after taking an antacid:
- Chlorodiazepoxide (Librium™)
- Diazepam (Valium™)
- Digoxin (Lanoxin™)
- Ibuprofen (Advil™, Motrin™)
- Indomethacin (Indocin™)
- Milk or foods that contain calcium
- Naproxen (Aleve™, Midol™, Naprosyn™, Pamprin™, Anaprox™)
- Tetracyclines (like doxycycline, minocycline, and tetracycline)
- Aluminum carbonate
- Aluminum hydroxide
- Aluminum magnesium hydroxide
- Dihydroxyaluminum sodium carbonate
Aluminum may cause constipation.
- Calcium carbonate
- Calcium may cause constipation
- Calcium may cause more acid to be released if used for a long period of time
- Magnesium carbonate
- Magnesium hydroxide
- Magnesium oxide
- Magnesium trisilicate
Magnesium may cause diarrhea.
- Sodium bicarbonate
- Sodium may cause distension or gas
- Sodium should not be used by people with congestive heart failure, kidney failure, swelling, liver conditions, or who are on low-sodium diets
- Aluminum hydroxide and magnesium carbonate
- Aluminum hydroxide and magnesium hydroxide
- Aluminum hydroxide and magnesium trisilicate
- Calcium carbonate and magnesium carbonate
- Calcium carbonate and magnesium hydroxide
- Potassium bicarbonate and sodium bicarbonate
- Cimetidine™ - Tagamet™
- Famotidine™ - Pepcid™|
- Nizatidine™ - Axid™
- Ranitidine - Zantac™
Cimetidine affects how many other drugs work. It's best to talk to a health care provider before taking cimetidine.
- Lansoprazole - Prevacid™
- Omeprazole - Prilosec™ Zegerid™
- Pantoprazole - Protonix™
- Rabeprazole - Aciphex™
PPIs should not be taken by people with serious liver disease or low levels of magnesium.
Where can I learn more?
To learn more about heartburn and reflux, please visit these websites: