can make changes in the immune system of times uncontiosness. In this study was founda person. On the contrary, methadone and that the use of buprenorphine in somebuprenorphine can restore the immune patients can have a deficient in salivationfunction and cytokine concentration. but normal saline was used to overcome thisCytokine is a molecule that is secreted by problem. This study does not show any otherthe cells in the immune system; this major secondary effects on patients the usemolecule helps to regulate the body. In a of buprenorphine on patients understudy made by Kapadia et al. (2005) and treatment.cited by Sacerdote et al. (2008) was foundthat a long lasting treatment with methadone Buprenorphine Treatment Duringand buprenorphine normalized the HPA axis Pregnancy and After Deliveringwhen altered when using heroin. The HPAaxis is part of the hypothalamus which is Pregnancy is a time were women arelocated in the brain; this part of the brain is susceptible to put the fetus in danger duringresponsible for the communication between the use of any medicine. Any treatment mustthe nervous system and the endocrine be supervised by a doctor that could offersystem. Many times this communication is the best medication for that mother anddamage because of drug abuse. Another child. Instead the use of a drug likestudy made by Mei et al. (2010) presented buprenorphine during and after the birth of athat a patient using buprenorphine as child can be an alternative for opioidtreatment shows a reduce withdrawal and patients. Most of the time the use ofcraving for heroin. In addition, alleviates methadone has been the treatment preferrednegative reinforcement such as abstinence by physicians but has been found thatand heroin-related cues. This shows that the buprenorphine treatment is less harmful fortreatment of heroin addiction has it benefits the mother and the child. According towhen buprenorphine is used. Martin (2006) has been found that a treatment with buprenorphine duringSecondary Effects of Buprenorphine pregnancy shows better results when using Most of the drugs used to treat any methadone. Martin (2006) mentions that thatkind of illness have secondary effects. When half of the newborns show withdrawal afterbuprenorphine is used on patients that are 72 hours after birth when usingunder a treatment of opioids such as heroin buprenorphine. When women are treatedand as treatment of post operatory patient. with buprenorphine there is no evidenceOn a research by Johnson et al. (2005) they showing that breastfeeding harms the baby,found that after the treatment using since buprenorphine has poorbuprenorphine most of the patients bioavailability. Martin (2006) mentions thatpresented nausea/vomiting and dizziness. a woman that is treated with buprenorphineThis symptoms seem to be normal because it during pregnancy a effort should be done to prevent withdrawal. This is accomplished by
giving the mother an appropriate dose methadone as a treatment is because theirduring pregnancy. previous experience with the drug. Pinto says that patients that have been using opioid for a long period of time had better results when using methadone thanBrain Response to Buprenorphine buprenorphine. Although the study made by Through history science has move Pinto et al. (2010) proved that the patientsforward greatly. Technology has been a tool that were under buprenorphine achievedthat science had used to help their cause. sustained abstinence that those participantsThe inclusion of scans to see how the brain using methadone. In addition, the patientsreacts in certain conditions has helped using methadone complained about morescience to help its patients. A study made by side effect that those using buprenorphine.Mei et al. (2010) presented how the brain Pinto et al. (2010) explained that the patientsreacts when using heroin and buprenorphine using methadone had side effects such as;using a MRI. This study showed a constipation, sweating, and sedation.diminution of craving in 5 minutes when Otherwise, the patients using buprenorphineusing bupre