0 thousand hectares that are not suitable for cultivation.
The long way to develop the virus-resistant beans.
The search for bean varieties resistant to the golden mosaic virus (BGMV) begun in the 70’s. It was hoped to obtain plants immune to this disease through conventional breeding methods. Thousands of lines were evaluated for natural resistance or immunity to the disease, but the extensive screening of common bean germplasm found no genotypes with satisfactory level of resistance to BGMV. With the advent of genetic engineering new strategies have been employed in addition to conventional breeding. Finally a successful strategy was found. The strategy was the use of RNA interference (RNAi) that mimics natural silencing mechanisms. Infected plants naturally produce silencing mechanisms that interfere with the virus in the bean cells, unfortunately not effective enough against this disease. The new “vaccinated” variety produces small fragments of RNA that will activate its defense mechanism to silence the viral rep gene, which leads to the synthesis of an essential protein for the replication of the virus. Consequently, without this protein, replication of the virus is compromised and the plants become resistant to the disease.
Safety and the way from research to seed market
Safety precautions for modern agricultural biotechnologies start at the very beginning of the research at the lab, and continue through the different phases of the development. Only when detailed scientific assessments determine it to be innocuous is the new development considered for commercial use. Prior to the submission for the commercial release, a comparison between the virus-resistant beans and its parental conventional/non-modified variety in all the ecosystems where the beans are cultivated in Brazil had been conducted by a consortium of 10 research centers over several years. Results showed that the transgenic beans do not differ in the environmental impact compared to its non-engineered parent beans. Additionally, the transgenic 