I have a wp 3.5 multisite and sometimes the page fail to load..I got this msg on chromeOops! Google Chrome could not connect to domain.xError 7 (net::ERR_TIMED_OUT): The operation timed out.on Firefox got thisServer not foundThe connection has timed outUpdate infos 2:This a WordPress or hosting or isp issue?!I scan my mulstiste wp site before a little moment with P3 (Plugin Performance Profiler):WordPress Plugin Profile Report:Report date: 24 January 2013Theme name: Pages browsed: 18Avg. load time: 1.7010 secNumber of plugins: 25Plugin impact: 45.81% of load timeAvg. plugin time: 0.7792 secAvg. core time: 0.4346 secAvg. theme time: 0.4586 secAvg. mem usage: 25.86 MBAvg. ticks: 17,257Avg. db queries : 139.33Margin of error : 0.0287 secPlugin list:P3 (Plugin Performance Profiler) - 0.0088 sec - 1.12%Bwp Google Xml Sitemaps - 0.0605 sec - 7.76%Google Analytics For Wordpress - 0.0200 sec - 2.57%Jw Player Plugin For Wordpress - 0.0241 sec - 3.09%Google Analytics Social Engagement Tracking Code - 0.0005 sec - 0.06%Multisite Toolbar Additions - 0.0039 sec - 0.50%Multisite User Management - 0.0044 sec - 0.57%My Gallery - 0.0188 sec - 2.41%Nextgen Gallery - 0.0109 sec - 1.39%NextScripts: SNAP Pro Upgrade Helper - 0.0060 sec - 0.77%SEO Ultimate - 0.2213 sec - 28.40%Social Networks Auto Poster Facebook Twitter G - 0.0767 sec - 9.84%Use Google Libraries - 0.0140 sec - 1.80%Watermark Hotlinked Images - 0.0007 sec - 0.09%Wordpress Mu Domain Mapping - 0.2089 sec - 26.82%WP Smush.it NextGEN Gallery Integration - 0.0004 sec - 0.05%WP Smush.it - 0.0014 sec - 0.17%Admin Locale - 0.0028 sec - 0.36%Contact Form 7 - 0.0166 sec - 2.13%Really Simple CAPTCHA - 0.0004 sec - 0.06%Simple Ads Manager - 0.0068 sec - 0.88%Top 10 - 0.0154 sec - 1.98%Welcome Popup - 0.0278 sec - 3.57%Wordpress Social Share Buttons - 0.0023 sec - 0.30%WP-Filebase - 0.0258 sec - 3.32%
Random fail to load wordpress multisite on Chrome & Firefox browser
wordpress;shared hosting;firefox;google chrome;isp
So based on the above discussion the issue is with your ISP/server environment.  Either it is under too heavy of an overall load (the reseller is overselling), is underpowered, or one of your plugins is rogue and causing the CPU to strain.I would lean more towards the former as the cause of your problems.  When purchasing shared server space, you really have no idea how many other sites are on that server nor do you really know how robust that server is.  My guess is that moving to your own hosting on a VPS or to WordPress-specific hosting will resolve all of the issues.