Sai Kit Lam
Affiliation: University of Malaya
- Nipah virus encephalitis outbreak in MalaysiaSai Kit Lam
Department of Medical Microbiology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
Clin Infect Dis 34:S48-51. 2002..The Island flying fox (Pteropus hypomelanus; the fruit bat) is a likely reservoir of this virus. The outbreak in Malaysia was controlled through the culling of >1 million pigs...
- Isolation of Nipah virus from Malaysian Island flying-foxesKaw Bing Chua
Department of Medical Microbiology, Faculty of Medicine, University of Malaya, 50603 Lumpur, Kuala, Malaysia
Microbes Infect 4:145-51. 2002..The isolation of Nipah virus from the Island flying-fox corroborates the serological evidence that it is one of the natural hosts of the virus...
- Nipah virus--a potential agent of bioterrorism?Sai Kit Lam
Department of Medical Microbiology, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia
Antiviral Res 57:113-9. 2003..From pigs, the virus was also transmitted to other animals such as dogs, cats, and horses. The Nipah virus has the potential to be considered an agent of bioterrorism...
- Nipah virus infection: pathology and pathogenesis of an emerging paramyxoviral zoonosisKum Thong Wong
University of Malaya, Kuala Lumpur, Malaysia
Am J Pathol 161:2153-67. 2002..Infection of endothelial cells and neurons as well as vasculitis and thrombosis seem to be critical to the pathogenesis of this new human disease...
- Preventive transfusion in Dengue shock syndrome-is it necessary?Lucy Chai See Lum
Department of Pediatrics, University of Malaya Medical Centre, Kuala Lumpur, Malaysia
J Pediatr 143:682-4. 2003..05) and none in hemorrhage (P=.136) were observed. Preventive transfusions did not produce sustained improvements in the coagulation status in DSS...
- Neurovirulence of four encephalitogenic dengue 3 virus strains isolated in Malaysia (1992-1994) is not attributed to their envelope proteinMun Yik Fong
Department of Parasitology, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia
Trans R Soc Trop Med Hyg 98:379-81. 2004..Multiple sequence alignment revealed a high degree of similarity in the E protein of the strains suggesting that neurovirulence of these four encephalitogenic strains is not attributed to this protein...
- Localization of dengue virus in naturally infected human tissues, by immunohistochemistry and in situ hybridizationKala Jessie
Department of Pathology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia
J Infect Dis 189:1411-8. 2004..Positive-strand viral RNA was detected in the same IHC-positive cells found in the spleen and blood-clot samples. The strong, positive ISH signal in these cells indicated a high copy number of viral RNA, suggesting replication...
- A golden hamster model for human acute Nipah virus infectionK Thong Wong
Department of Pathology, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia
Am J Pathol 163:2127-37. 2003..The golden hamster is proposed as a suitable model for further studies including pathogenesis studies, anti-viral drug testing, and vaccine development against acute Nipah infection...
- Preparing for introduction of a dengue vaccine: recommendations from the 1st Dengue v2V Asia-Pacific MeetingSai Kit Lam
Office of the Vice Chancellor, University of Malaya, Jalan Pantai Baru, 50603 Kuala Lumpur, Malaysia
Vaccine 29:9417-22. 2011....
- Risk factors for hemorrhage in severe dengue infectionsLucy Chai See Lum
Department of Pediatrics, University of Malaya Medical Center, Kuala Lumpur, Malaysia
J Pediatr 140:629-31. 2002..The duration of shock (OR, 2.11; 95% CI, 1.13 to 3.92; P =.019) and low-normal hematocrit at the time of shock (OR, 0.72; 95% CI, 0.55 to 0.95; P =.020) were risk factors of severe hemorrhage...
- Echovirus 7 associated encephalomyelitisLucy Chai See Lum
Department of Pediatrics, University of Malaya Medical Center, 50603, Kuala Lumpur, Malaysia
J Clin Virol 23:153-60. 2002..In 2000, an outbreak of HFMD resulted in the deaths of three children who had rapid cardio-respiratory decompensation and one child who survived a central nervous system infection...
- Membrane fusion tropism and heterotypic functional activities of the Nipah virus and Hendra virus envelope glycoproteinsKatharine N Bossart
Department of Microbiology and Immunology, Uniformed Services University, Bethesda, Maryland 20814, USA
J Virol 76:11186-98. 2002..However, no heterotypic activity was observed with envelope glycoproteins of the morbilliviruses Measles virus and Canine distemper virus...