Remus was well aware that his witch would do anything to protect her loved ones, but this was a shocking and drastic revelation. Memory charms such as those could only be cast by advanced witches and wizards, and it was obvious by her state, and the sadness he felt through their bond, that she knew there was a chance they'd never be reversed. Remus couldn’t articulate any words to ease her conscious, and he knew she didn’t need someone to validate her choices. All he could do was hold her, and let her process, and after a few minutes he felt her breathing even out as she fell back asleep. Someone moved around upstairs and he hoped it was only Sirius, hesitant to let Hermione go.