Some of the country 's oldest schools are founded in Intramuros , these are the University of Santo Tomas ( 1611 ) , Colegio de San Juan de Letran ( 1620 ) , and Ateneo de Manila University ( 1859 ) . Only Colegio de San Juan de Letran remains at Intramuros ; the University of Santo Tomas transferred to a new campus at Sampaloc in 1927 , and Ateneo left Intramuros for Loyola Heights , Quezon City ( while still retaining " de Manila " in its name ) in 1952 . Other prominent educational institutions include the Manila High School and the University of the City of Manila .