US 40 and NJ 50 follow the Harding Highway , a two @-@ lane undivided road , turning to the northeast and crossing the Great Egg Harbor River . Upon passing over the river , enters Mays Landing and turns north , encountering CR 617 before passing over an abandoned railroad line and heading into the downtown area of Mays Landing . Here , the road crosses CR 559 , and US 40 splits from NJ 50 by turning east along that road . Meanwhile , Route 50 continues north on Cape May Avenue , passing through developed areas . It leaves Mays Landing and heads into back into forests . The route turns to the northeast , passing near the Clover Leaf Lakes residential development , before coming to an interchange with US 322 ( Black Horse Pike ) .