Putative transcription factor, weakly pro-apoptotic when overexpressed (By similarity). Tumor suppressor. Required for early embryonic stem cell development.
Displaces isoform 4 at the onset of differentiation, required for repression of stemness genes.
Subcellular locations: Cytoplasm, Nucleus, Cytoplasm, Cytoskeleton, Spindle
Translocates to the nucleus after pro-apoptotic stimuli (By similarity). Translocates to the mitotic spindle upon loss of interaction with H3K4me3 during early mitosis.
Ubiquitous.