Required for proper chromosome biorientation through the detection or correction of syntelic attachments in mitotic spindles.
Subcellular locations: Cytoplasm, Cytoskeleton, Microtubule organizing center, Centrosome, Chromosome, Centromere, Kinetochore
Localizes at the centrosomes throughout the cell cycle, only dissociating during cytokinesis. Localizes at the kinetochore from prometaphase until anaphase.