May be involved in the structural organization of the nucleus and in the post-mitotic nuclear assembly. Plays an important role, together with LMNA, in the nuclear anchorage of RB1.
TP and TP5 may play a role in T-cell development and function. TP5 is an immunomodulating pentapeptide.
Subcellular locations: Nucleus, Chromosome
Expressed diffusely throughout the nucleus.
Expressed in many tissues. Most abundant in adult thymus and fetal liver.