Intrinsically disordered protein which may negatively regulate mTOR signaling pathway by stabilizing the mTOR complex component DEPTOR . Negatively regulates angiogenesis . Negatively regulates cell growth (, ). Negatively regulates neurite outgrowth in hippocampal neurons (By similarity).
Subcellular locations: Cell membrane
Widely expressed, including in breast epithelial cells and endothelial cells (at protein level). Expression is down-regulated in advanced breast tumors (at protein level).