PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides. Does not exhibit detectable activity toward sn-2-arachidonoyl- or linoleoyl-phosphatidylcholine or -phosphatidylethanolamine.
Subcellular locations: Secreted, Cytoplasm
Abundantly expressed in heart, skeletal muscle, kidney, liver and pancreas.