Catalyzes the deubiquitination of SPDL1 . Plays a role in the repair of UV-induced DNA damage via deubiquitination of ERCC1, promoting its recruitment to DNA damage sites . May be involved in the maintenance of photoreceptor function . May play a role in normal retinal development (By similarity). Plays a role in cell migration .
Subcellular locations: Photoreceptor inner segment, Cytoplasm, Nucleus
Widely expressed. High expression is detected in the cerebellum. In the eye, it is expressed at high levels in the optic nerve, sclera and retina, with relatively low levels in the choroid, lens and retinal pigment epithelium .