This enzyme is involved in the de novo synthesis of CTP, a precursor of DNA, RNA and phospholipids. Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as a source of nitrogen. This enzyme and its product, CTP, play a crucial role in the proliferation of activated lymphocytes and therefore in immunity.
Subcellular locations: Cytoplasm, Cytosol
Mainly cytosolic but when active detected in long filamentous structures . Co-localizes with TNK2 in the cytosolic filaments (By similarity).
Widely expressed.