Transcription factor that plays an important role in the regulation of lymphocyte differentiation. Plays an essential role in regulation of B-cell differentiation, proliferation and maturation to an effector state. Involved in regulating BCL2 expression and controlling apoptosis in T-cells in an IL2-dependent manner.
Subcellular locations: Nucleus, Cytoplasm
Subcellular locations: Nucleus
Subcellular locations: Nucleus
Subcellular locations: Nucleus
Subcellular locations: Nucleus, Cytoplasm
Subcellular locations: Cytoplasm
Expressed most strongly in peripheral blood leukocytes, the spleen, and the thymus.