Plays a role in vesicle trafficking and exocytosis inhibition. In pancreatic beta-cells, inhibits insulin secretion probably by interacting with and regulating STX1A and STX4, key t-SNARE proteins involved in the fusion of insulin granules to the plasma membrane. Also plays a role in neurotransmitter release by inhibiting basal acetylcholine release from axon terminals and by preventing synaptic fatigue upon repetitive stimulation (By similarity). Promotes as well axonal outgrowth .
Subcellular locations: Cytoplasm, Cell membrane, Membrane
Cytoplasmic, and associated with vesicular membranes and the plasma membrane.
Detected in kidney, hippocampus and lung carcinoma.