Central nervous system-specific myelin protein that increase myelin genes expression during oligodendrocyte differentiation. Promotes oligodendrocyte terminal differentiation.
Subcellular locations: Cell membrane
In the CNS, enriched in the myelin paranodal and inner loop membranes, but not that of the PNS. Enriched in the leading edge of extending processes.
Brain specific; expressed in oligodendrocytes (, ). Expressed in oligodendrocytes in remyelinating multiple sclerosis plaques .