Mediates the anchoring of the endoplasmic reticulum to microtubules.
High-affinity epithelial cell surface receptor for the FZD8-related low molecular weight sialoglycopeptide APF/antiproliferative factor. Mediates the APF antiproliferative signaling within cells.
Subcellular locations: Endoplasmic reticulum membrane, Cell membrane, Cytoplasm, Cytoskeleton, Cytoplasm, Perinuclear region
Translocates to the perinuclear region upon APF-stimulation.