Catalyzes the post-translational modification of target proteins by phosphopantetheine. Can transfer the 4'-phosphopantetheine moiety from coenzyme A, regardless of whether the CoA is presented in the free thiol form or as an acetyl thioester, to a serine residue of a broad range of acceptors including the acyl carrier domain of FASN.
Subcellular locations: Cytoplasm, Cytosol
Detected in heart, skeletal muscle, placenta, testis, brain, pancreas, liver and kidney.