Guanine nucleotide exchange factor (GEF) activating RAB10. Promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB10 into its active GTP-bound form. Thereby, stimulates SLC2A4/GLUT4 glucose transporter-enriched vesicles delivery to the plasma membrane in response to insulin.
Subcellular locations: Cytoplasmic vesicle membrane, Cell membrane, Cytoplasm, Cytosol
Associates with SLC2A4/GLUT4 storage vesicles.