Catalyzes the hydrolysis of ribonucleotide and deoxyribonucleotide monophosphates, releasing inorganic phosphate and the corresponding nucleoside ( , ). AMP is the major substrate but can also hydrolyze dCMP and IMP ( , ).
Subcellular locations: Cytoplasm
Highly expressed in skeletal muscle. Detected at intermediate levels in heart, brain, kidney and pancreas.