Outward rectifying potassium channel. Produces rapidly activating outward rectifier K(+) currents. Activated by high intracellular sodium and chloride levels ( ). Channel activity is inhibited by ATP and by inhalation anesthetics, such as isoflurane  (By similarity). Inhibited upon stimulation of G-protein coupled receptors, such as CHRM1 and GRM1 .
Subcellular locations: Cell membrane