Chaperone protein which plays an important role in mitochondrial iron-sulfur cluster (ISC) biogenesis. Interacts with and stabilizes ISC cluster assembly proteins FXN, NFU1, NFS1 and ISCU . Regulates erythropoiesis via stabilization of ISC assembly (, ). May play a role in cell cycle regulation via its interaction with and promotion of degradation of TP53 (, ). May play a role in the control of cell proliferation and cellular aging (By similarity).
Subcellular locations: Mitochondrion, Nucleus, Nucleolus, Cytoplasm