This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region.
Subcellular locations: Secreted, Extracellular space, Extracellular matrix
Detected in fibroblasts (at protein level) . Restricted to cartilage .