Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate homeostasis of late endocytic pathway, including endosomal positioning, maturation and secretion . Plays a role in NTRK2/TRKB axonal anterograde transport by facilitating the association of NTRK2/TRKB with KLC1 . May be involved in targeting uroplakins to urothelial apical membranes (By similarity).
Subcellular locations: Membrane, Late endosome
Expressed primarily in testis.