Transcriptional factor (, ). Plays a critical role in neuronal morphogenesis and survival of sensory neurons (By similarity). Represses the corneal epithelium differentiation . Acts also as a metabolic regulator, by modulating insulin sensitivity in pancreatic beta cells and skeletal muscle cells . Inhibits transcriptional inducers of adipogenesis and has a repressive role in the expression of several adipokines, including leptin .
Subcellular locations: Nucleus
Widely expressed.