Potassium channel subunit. Modulates channel activity by shifting the threshold and the half-maximal activation to more negative values.
Subcellular locations: Cell membrane
Has to be associated with KCNB1 or possibly another partner to get inserted in the plasma membrane. Remains intracellular in the absence of KCNB1.
Detected in lung, liver, kidney, pancreas, spleen, thymus, prostate, testis, ovary and colon.