Scaffold subunit of various histone acetyltransferase (HAT) complexes, such as the MOZ/MORF and HBO1 complexes, which have a histone H3 acetyltransferase activity ( ). Plays a key role in HBO1 complex by directing KAT7/HBO1 specificity towards histone H3 'Lys-14' acetylation (H3K14ac) . Some HAT complexes preferentially mediate histone H3 'Lys-23' (H3K23ac) acetylation . Positively regulates the transcription of RUNX1 and RUNX2 .
Subcellular locations: Nucleus, Chromosome, Cytoplasm
Localization to the nucleus depends on KAT6A, ING5 and MEAF6 (, ). Localizes to transcription start sites .
High levels in testis.