Retinol dehydrogenase with a clear preference for NADP. Converts all-trans-retinol to all-trans-retinal. Has no detectable activity towards 11-cis-retinol, 9-cis-retinol and 13-cis-retinol.
Subcellular locations: Microsome membrane, Endoplasmic reticulum membrane
Detected in retina, kidney, liver, small intestine, placenta, lung, heart and skeletal muscle.