Olfactory receptor. Activated by the synthetic floral odorant, lyral, and by alpha-cedrene, a sesquiterpene constituent of cedarwood oil. Its activation increases intracellular Ca(2+) (, ). Acts as a key regulator of myogenesis through its actions on cell migration and adhesion by activating the Ca(2+)-dependent AKT signal transduction pathway (By similarity). Acts also as a regulator of angiogenesis . Moreover, plays a role in the regulation of lipid accumulation in hepatocytes via the cAMP-PKA pathway . May be involved in sperm chemotaxis and motility (By similarity).
Subcellular locations: Cell membrane
Expressed in both the aorta, the coronary artery and umbilical vein endothelial cells (HUVECs) (at protein level).