Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.
Subcellular locations: Endoplasmic reticulum membrane
Is a tail-anchored protein that exploits the TCR40 pathway for insertion into the endoplasmic reticulum.
Expressed in pancreatic islets.