RNA-dependent helicase . Plays an important role in the assembly of the mitochondrial large ribosomal subunit (, ). Required for optimal function of the zinc-finger antiviral protein ZC3HAV1 (By similarity). Associates with mitochondrial DNA . Involved in nervous system development and differentiation through its involvement in the up-regulation of a number of genes which are required for neurogenesis, including GSC, NCAM1, neurogenin, and NEUROD (By similarity).
Subcellular locations: Cytoplasm, Mitochondrion, Mitochondrion matrix, Mitochondrion nucleoid
Localizes to mitochondrial RNA granules found in close proximity to the mitochondrial nucleoids (, ). Relocalizes to stress granules upon heat stress .