Acts as an adapter protein of the FYN and LCP2 signaling cascades in T-cells (By similarity). May play a role in linking T-cell signaling to remodeling of the actin cytoskeleton (, ). Modulates the expression of IL2 (By similarity). Involved in platelet activation (By similarity). Prevents the degradation of SKAP1 and SKAP2 . May be involved in high affinity immunoglobulin epsilon receptor signaling in mast cells (By similarity).
Subcellular locations: Cytoplasm, Nucleus, Cell junction
Colocalizes with TMEM47 at cell-cell contacts in podocytes.
Expressed in hematopoietic tissues such as myeloid and T-cells, spleen and thymus. Not expressed in B-cells, nor in non-lymphoid tissues.