Plays a fundamental role in microtubule-organizing center structure and function.
As a component of the TREX-2 complex, involved in the export of mRNAs to the cytoplasm through the nuclear pores.
Subcellular locations: Cytoplasm, Cytoskeleton, Microtubule organizing center, Centrosome, Nucleus, Nucleolus, Nucleus envelope, Nucleus, Nuclear pore complex, Cytoplasm, Cytoskeleton, Microtubule organizing center, Centrosome, Centriole
Centrosome of interphase and mitotic cells . Localizes to centriole distal lumen . Localization at the nuclear pore complex requires NUP153 and TPR .