Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate. Participates in stress granule (SG) assembly. May allow ATP production from extracellular deoxyinosine in conditions of energy deprivation.
Subcellular locations: Cytoplasm, Cytoplasmic granule, Nucleus
Recruited to stress granules but not to processing bodies upon arsenite or clotrimazole treatment or energy deprivation.
Mainly expressed in liver, lung and colon.