Endoplasmic reticulum (ER)-anchored autophagy regulator which exists in an inactive state under basal conditions but is activated following cellular stress . When activated, induces ER fragmentation and mediates ER delivery into lysosomes through sequestration into autophagosomes via interaction with ATG8 family proteins . Required for collagen quality control in a LIR motif-independent manner (By similarity).
Subcellular locations: Endoplasmic reticulum membrane