Required for mitotic centrosome maturation and bipolar spindle assembly ( ). Appears to be a major regulator of pericentriolar material (PCM) recruitment, centrosome maturation, and centriole duplication ( ). Centrosome-specific activating scaffold for AURKA and PLK1 .
Subcellular locations: Cytoplasm, Cytoskeleton, Microtubule organizing center, Centrosome, Centriole
Pericentriolar location in mitotic centrosomes.