Plays a role in the formation of lipid droplets (LDs) which are storage organelles at the center of lipid and energy homeostasis (By similarity). Regulates the morphology, size and distribution of LDs (By similarity). Mediates the formation of endoplasmic reticulum-lipid droplets (ER-LD) contact sites by forming a complex with RAB18 and ZW10 (By similarity). Binds to phosphatidylinositol 3-phosphate (PtdIns3P) through FYVE-type zinc finger (By similarity).
Subcellular locations: Golgi apparatus, Golgi apparatus, Golgi stack, Endoplasmic reticulum, Preautophagosomal structure, Lipid droplet, Mitochondrion
Resides predominantly in the cisternal stacks of the Golgi. Colocalizes with TRIM13 on the perinuclear endoplasmic reticulum. During starvation conditions, localizes to omegasomes which are endoplasmic reticulum connected strutures at the origin of preautophagosomal structures. Localizes to lipid droplets in the presence of oleic acid (By similarity).