Part of the MIS12 complex which is required for normal chromosome alignment and segregation and kinetochore formation during mitosis. May act as a cotranscription partner of NFE2L2 involved in regulation of polyamine-induced transcription of SSAT.
Subcellular locations: Nucleus, Chromosome, Centromere, Kinetochore
Associated with the kinetochore.
Highest levels of expression in heart and skeletal muscle, with significant levels expressed in kidney and liver.