Collagen VI acts as a cell-binding protein.
Subcellular locations: Secreted, Extracellular space, Extracellular matrix
Deposed in the extracellular matrix of skeletal muscle.
Expressed in skin, followed by lung, small intestine, colon and testis. In skin, it is expressed in the epidermis with strongest staining in suprabasal viable layers. In ATOD patients, it is absent in the most differentiated upper spinous and granular layers (at protein level).