May be involved in endothelial cell morphology changes during cell spreading. In the retinal pigment epithelium, may regulate the biogenesis of melanosomes and promote their association with the apical cell surface by inducing gamma-tubulin redistribution (By similarity).
Subcellular locations: Apical cell membrane, Cell junction, Tight junction, Cytoplasm, Cytoskeleton
Associates with cortical F-actin.
Abundant in retina and melanoma; also in brain, placenta, lung, kidney and pancreas.