Seems to act as a chloride ion channel . Plays a role in retina development .
Subcellular locations: Endoplasmic reticulum membrane, Golgi apparatus membrane, Nucleus membrane
Within the endoplasmic reticulum (ER), localizes to the mitochondria-associated ER membrane, a zone of contact between the ER and mitochondrial membranes.
Expressed in the retina of the eye, with extensive expression in the lamina cribrosa, optic nerve, ganglion cell layer, inner nuclear layer, outer nuclear layer and retinal pigment epithelium.