Plays a role in spermatogenesis . When overexpressed, prevents nuclear localization of HIF1A (By similarity).
Subcellular locations: Cytoplasm, Cytoplasm, Cytoskeleton, Microtubule organizing center, Centrosome, Centriole
In mature spermatozoa, localizes to the centriole and midpiece . The 27-kDa peptide associates with the fibrous sheath in mature spermatozoa and localizes to the principal piece of sperm tail, while the 55-kDa peptide localizes to the midpiece (By similarity). Detected in the cytoplasm of almost all spermatogonial cells within the seminiferous tubules (By similarity).
Expressed in the testis, in spermatozoa (at protein level) (, ). Expressed in actively dividing fetal tissues, including sternum, intestine, limb, kidney and stomach .