Has been proposed to act as a receptor for neuronostatin, a peptide derived from the somatostatin/SST precursor . Involved in blood sugar regulation through the induction of glucagon in response to low glucose (By similarity).
(Microbial infection) Required for intoxication by Pseudomonas aeruginosa exotoxin A and Campylobacter jejuni CDT. May contribute to the retrograde transport of bacterial toxins, including cholera toxin, from the trans-Golgi network to the endoplasmic reticulum.
Subcellular locations: Cell membrane, Golgi apparatus, Trans-Golgi network membrane