May function as a growth and differentiation factor involved in neuritogenesis. May induce ERBB3 activation.
Subcellular locations: Cell membrane, Synaptic cell membrane, Endoplasmic reticulum membrane, Golgi apparatus membrane, Cell surface, Secreted
In neurons, localizes to synaptic junctions. Also detected in the endoplasmic reticulum and the Golgi. Partially enriched in lipid rafts.
Detected in cerebrospinal fluid (at protein level) . Detected in urine (at protein level) . Expressed in brain (at protein level) .