Has in vitro nucleotide phosphodiesterase activity with nucleoside triphosphates, such as ATP (, ). Has in vitro activity with p-nitrophenyl-TMP . Has lower activity with nucleoside diphosphates, and no activity with nucleoside monophosphates (, ). Has in vitro activity with CDP-choline, giving rise to CMP and phosphocholine. Has in vitro activity with CDP-ethanolamine . Does not have sphingomyelin phosphodiesterase activity (, ).
Subcellular locations: Secreted
Detected in blood serum. Detected in macrophages (at protein level).