Cell surface receptor that may play a role in the innate and adaptive immune response.
Subcellular locations: Cell membrane, Cytoplasm
Sequestered in cytoplasmic vesicles in resting platelets . Transported to the cell surface after stimulation by thrombin . Soluble fragments can be released into the serum by proteolysis .
Detected in platelets, monocytic leukemia and in T-cell leukemia.