Functions as a regulator of cell cycle progression by stabilizing the FBXO5 protein and promoting cyclin-A accumulation during interphase. May play a role in cytokinesis.
Subcellular locations: Nucleus, Cytoplasm, Cytoskeleton, Microtubule organizing center, Centrosome, Cytoplasm, Cytoskeleton, Spindle
Associates with the mitotic spindle through anaphase and remains within the midzone and midbody until completion of cytokinesis.
Expressed in various cell lines (at protein level). Expressed in a wide range of tissues including brain and adrenal.