May play an important role in maintaining centrosome integrity during mitosis.
Subcellular locations: Cytoplasm, Cytoskeleton, Microtubule organizing center, Centrosome, Cytoplasm, Cytoskeleton, Spindle pole
Localizes at spindle poles and/or centrosomes in both mitotic and interphase cells . Spindle pole localization is more pronounced during mitosis . Centrosomal localization culminates at prophase .
Expressed in chondrosarcoma, melanoma, cartilage and testis, but not in other normal tissues.