Zinc finger nuclear factor involved in transcription by regulating chromatin structure and organization (, ). Involved in the pluripotency and differentiation of embryonic stem cells by regulating SOX2, POU5F1/OCT4, and NANOG . By binding PBX1, prevents the heterodimerization of PBX1 and HOXA9 and their binding to DNA (By similarity). Regulates neuronal development and neural cell differentiation .
Subcellular locations: Nucleus