Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex. The BCR(KLHL7) complex acts by mediating ubiquitination and subsequent degradation of substrate proteins. Probably mediates 'Lys-48'-linked ubiquitination.
Subcellular locations: Nucleus, Cytoplasm
Colocalizes with CUL3 in punctate structures at the perinuclear region of the cytoplasm.
Widely expressed, with highest levels in adult and fetal heart, CNS and adult testis.