Calcium-binding protein which may have a role in calcium homeostasis (By similarity). Acts as a non-receptor guanine nucleotide exchange factor which binds to and activates guanine nucleotide-binding protein (G-protein) alpha subunit GNAI3 (By similarity).
Anorexigenic peptide, seems to play an important role in hypothalamic pathways regulating food intake and energy homeostasis, acting in a leptin-independent manner. May also exert hypertensive roles and modulate blood pressure through directly acting on peripheral arterial resistance.
Subcellular locations: Golgi apparatus, Membrane, Cytoplasm, Secreted, Endoplasmic reticulum, Nucleus envelope
Golgi retention is mediated by its N-terminal region.
Subcellular locations: Secreted
Predominantly expressed in spleen, testis and normal stomach.