Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels . Functions as a peroxisomal succinyl-coenzyme A thioesterase that can also hydrolyze glutaryl-CoA and long chain saturated acyl-CoAs .
Subcellular locations: Peroxisome
Strongest expression in liver and kidney and weaker expression in placenta, heart, and muscle.