Plays a role in the regulation of cell proliferation. Promotes activation of the AKT1 signaling pathway. Promotes phosphorylation of AKT1 at 'Ser-473'.
Subcellular locations: Golgi apparatus membrane, Cell membrane
Concentrated at cell-cell borders. Localizes at membranes in a microtubule-dependent manner.
Expressed in fibroblast and numerous cancer cell lines (at protein level).