Possesses similar cytotoxic and cytostimulatory activities to PRG2/MBP. In vitro, stimulates neutrophil superoxide production and IL8 release, and histamine and leukotriene C4 release from basophils.
Subcellular locations: Cytoplasmic granule
Localized to the eosinophil secondary granule.
Expressed in bone marrow. Not detected in placenta.