Does not exhibit calcium-activated chloride channel (CaCC) activity.
Subcellular locations: Endoplasmic reticulum membrane, Cell membrane
Colocalized with CALR/calreticulin . Shows an intracellular localization according to .
Highly expressed in brain, heart, kidney, lung, and skeletal muscle. Weakly expressed in bone marrow, fetal liver, placenta, spleen, thymus, osteoblasts and periodontal ligament cells.