Required for centriole duplication. Inhibition of centriole duplication leading to defects in cytokinesis.
Subcellular locations: Cytoplasm, Cytoskeleton, Microtubule organizing center, Centrosome, Centriole
Centriole-associated, asymmetrically localizes to the daughter centriole.
Widely expressed (at protein level). Highly expressed in testis. Also expressed in spleen, thymus, prostate, small intestine, colon and peripheral blood leukocytes.