Inhibits the transcriptional repressor activity of REST by inhibiting its binding to DNA, thereby derepressing transcription of REST target genes.
Acts as a bridge between FOXP3 and the corepressor TRIM28, and is required for the transcriptional repressor activity of FOXP3 in regulatory T-cells (Treg).
Subcellular locations: Nucleus
Colocalizes with REST in the nucleus.
Expressed in heart . Isoform 2: Highly expressed in regulatory T-cells (Treg) .