Microprotein involved in mitochondrial respiratory chain complex III (ubiquinol-cytochrome c oxidoreductase) and complex IV (mitochondrial cytochrome c oxidase complex) assembly . Required for the formation of mitochondrial supercomplexes (SCs) . Also required for the activation of the NLRP3 inflammasome (By similarity).
Subcellular locations: Mitochondrion inner membrane, Mitochondrion outer membrane, Mitochondrion intermembrane space
Expressed in monocytes and dendritic cells.