Metalloprotease which has proteolytic activity against the proteoglycan VCAN, cleaving it at the 'Glu-1428-|-1429-Ala' site. Cleaves VCAN in the pericellular matrix surrounding myoblasts, facilitating myoblast contact and fusion which is required for skeletal muscle development and regeneration.
Subcellular locations: Secreted, Extracellular space, Extracellular matrix, Cell surface
Expressed in fetal liver and kidney, but not in any of the adult tissues examined.