Involved in plasma membrane dynamics and cell process formation. Isoform 1 and isoform 2 are necessary for axonal and dendritic filopodia induction, for dendritic spine maturation and synapse formation in a palmitoylation-dependent manner.
Subcellular locations: Cell membrane, Cell projection, Filopodium membrane, Cell projection, Axon, Cell projection, Dendrite, Cell projection, Dendritic spine, Basolateral cell membrane, Apicolateral cell membrane
Translocation to the plasma membrane is enhanced upon stimulation of neuronal activity.
Widely expressed with highest expression in brain and testis and intermediate expression in heart and adrenal gland.