May function in protein sorting in late endosomes or multivesucular bodies (MVBs).
(Microbial infection) Involved in MVB-assisted maturation of hepatitis B virus (HBV).
Subcellular locations: Golgi apparatus membrane, Cytoplasmic vesicle membrane, Endosome membrane
Mainly localized to perinuclear vesicular structures . Colocalizes with HBV major surface antigen L and HBV core protein C in CD63-containing compartments . Colocalizes with HBV major surface antigen L to cis-Golgi-like structures .
Expressed in all but one (skeletal muscle) tissues examined.