Involved in the modulation of mTOR signaling and expression of mTOR complex components (, ). Involved in the regulation of cell proliferation and growth (, ). Involved in the control of actin-cytoskeleton organization .
Subcellular locations: Cytoplasm, Cytoplasm, Cytoskeleton, Spindle, Midbody
Mainly localized in the cytoplasm during interphase. During metaphase, TBCK accumulates at the mitotic spindle. At the end of mitosis, it is detected at the midbody.