Acts as a guanine nucleotide exchange factor (GEF) for CDC42 and RAC1 small GTPases. Through its activation of CDC42 and RAC1, may regulate neurite outgrowth (By similarity).
Subcellular locations: Cytoplasm, Cytoplasm, Perinuclear region
Mainly located near the cell surface.
Widely expressed. Expressed at low level in spleen, cerebellum, hippocampus and in substantia nigra.