Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes.
Subcellular locations: Apical cell membrane, Cytoplasm, Membrane, Cytoplasm, Cytoskeleton, Cytoplasm, Cytoskeleton, Microtubule organizing center, Centrosome
Found in the soluble fraction, associated with membranes, and associated with the cytoskeleton and the centrosome (By similarity). Colocalized with SHANK2 to the apical membrane of colonic crypt cells.
Expressed in colonic epithelial cells (at protein level). Widespread; most abundant in skeletal muscle.
Detected in brain.
Detected in brain, placenta, lung and kidney.
Detected in heart and skeletal muscle.