Plays a role in mitochondrial electron transport and mitochondrial respiration . Through its regulation of the mitochondrial function may play a role in normal postnatal skeletal growth and cartilage homeostasis (, ).
Subcellular locations: Secreted, Mitochondrion
Associated with membranes.
Predominant expression in adult kidney and testis and fetal kidney. Weaker expression found in placenta, ovary, prostate and small intestine (, ). Also expressed in skeletally-derived cells such as synoviocytes and articular cartilage chondrocytes .