Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity). V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity). May play a role in cilium biogenesis through regulation of the transport and the localization of proteins to the cilium (By similarity).
Subcellular locations: Membrane, Cytoplasmic vesicle, Clathrin-coated vesicle membrane, Cytoplasm, Cytoskeleton, Microtubule organizing center, Centrosome, Cell projection, Cilium
Localizes to centrosome and the base of the cilium.