Required for the transduction of an SCO1-dependent redox signal from the mitochondrion to ATP7A to regulate cellular copper homeostasis . May be required for the assembly of mitochondrial cytochrome c oxidase (By similarity).
Subcellular locations: Cytoplasm, Cytosol, Mitochondrion intermembrane space, Mitochondrion
Partitions between mitochondria and the cytosol in a copper-dependent manner. Enriched in the cytosol when intracellular copper concentrations are elevated.
Ubiquitously expressed. Highly expressed in skeletal muscle.