Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP.
Subcellular locations: Cytoplasm, Cytoskeleton, Cilium axoneme
Located in the proximal region of respiratory cilia.
Expressed in airway ciliated epithelial cells (at protein level) (, ). Not detected in spermatozoa (at protein level) .