Has sequence-specific DNA-binding activity and can function as transcriptional repressor (in vitro) . May be a regulator of cell cycle: THAP5 overexpression in human cell lines causes cell cycle arrest at G2/M phase .
Subcellular locations: Nucleus
Detected in heart (, ). Detected in brain and muscle (at protein level) . Highly expressed in the heart. Also found in brain and skeletal muscle (, ).