May play a role in male spermatogenesis. In vitro acts as inhibitor of MGAT1 activity causing cell surface proteins to carry mainly high mannose N-glycans. The function is mediated by its lumenal domain and occurs specifically in the Golgi. A catalytic glucosyltransferase activity is not detected. May be involved in regulation of Sertoli-germ cell interactions during specific stages of spermatogenesis.
Subcellular locations: Golgi apparatus membrane, Endoplasmic reticulum membrane
Expressed in testis. Poorly expressed in testis biopsies from men with impaired spermatogenesis.