RNA-binding protein that suppresses transcription of long non-coding RNAs (lncRNAs) (, ). LncRNAs are defined as transcripts more than 200 nucleotides that are not translated into protein (, ). Together with WDR82, part of a transcription termination checkpoint that promotes transcription termination of lncRNAs and their subsequent degradation by the exosome (, ). The transcription termination checkpoint is activated by the inefficiently spliced first exon of lncRNAs .
Subcellular locations: Chromosome
Recruited at sites of high RNA polymerase II occupancy.