Plasma membrane progesterone (P4) receptor coupled to G proteins . Seems to act through a G(i) mediated pathway . May be involved in oocyte maturation (By similarity). Also binds dehydroepiandrosterone (DHEA), pregnanolone, pregnenolone and allopregnanolone .
Subcellular locations: Cell membrane
Colocalizes with a lysosomal protein CTSD/cathepsin D.
Highly expressed in the hypothalamus . Also expressed in spinal cord, kidney and testis.