Plays a role in cell adhesion, and thereby in cell motility which requires repeated formation and disassembly of focal adhesions. Regulates microtubule-induced PTK2/FAK1 dephosphorylation, an event important for focal adhesion disassembly, as well as integrin beta-1/ITGB1 cell surface expression.
Subcellular locations: Cell junction, Focal adhesion, Cytoplasmic vesicle, Endosome
Within cytoplasmic vesicles, partially colocalizes with EEA1, an endosomal marker.