Adapter protein that anchors the radial spoke 1 (RS1) complex to the A microtubule of outer doublet microtubules in axonemes . The triple radial spokes (RS1, RS2 and RS3) are required to modulate beating of the sperm flagellum . May play a role in inhibiting signaling via MAPK1/ERK2 and MAPK3/ERK1 . Additionally, may play a role in the functioning of cilia (By similarity). Not required for the functioning of tracheal or ependymal cilia (By similarity).
Subcellular locations: Cytoplasm, Cytoskeleton, Flagellum axoneme, Cell projection, Cilium
Localizes to the axoneme of sperm cells and the cilia of tracheal epithelial cells.