Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs.
Subcellular locations: Nucleus, Cytoplasm
Enters into the nucleus in case of active transcription while it accumulates in cytosol when transcription level is low.