Does not exhibit calcium-activated chloride channel (CaCC) activity. Can inhibit the activity of ANO1.
Subcellular locations: Cell membrane
Shows predominantly an intracellular localization with a weak expression in the cell membrane.
Highly expressed in the brain. Intermediate levels in the retina and heart and low levels in the placenta, liver, lung, duodenum, kidney, testis and spleen. In brain areas, highest expression in the frontal and occipital cortices and in the cerebellum. Lower expression in the fetal brain than in the adult brain.