It is involved in synaptogenesis and promotes excitatory synapse differentiation (, ). Enhances neuronal dendrite outgrowth (, ).
Subcellular locations: Membrane, Secreted, Synapse
Expressed predominantly in the frontal lobe of the cerebral cortex of the brain. Also expressed in some astrocytic brain tumors such as astrocytomas, oligodendrogliomas, glioblastomas, gangliogliomas and primitive neuroectodermal tumors.