Receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP3 (By similarity). Receptor for adrenomedullin together with RAMP2 (, ). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase (, ).
Subcellular locations: Cell membrane
Predominantly expressed in the lung and heart.