Transcriptional activator . C/EBP are DNA-binding proteins that recognize two different motifs: the CCAAT homology common to many promoters and the enhanced core homology common to many enhancers. Required for the promyelocyte-myelocyte transition in myeloid differentiation .
Subcellular locations: Nucleus
Strongest expression occurs in promyelocyte and late-myeloblast-like cell lines.