Contributes to the regulation of alternative splicing of pre-mRNAs.
Subcellular locations: Cell junction, Adherens junction, Nucleus, Cytoplasm
In heart, localizes at area composita, the mixed-type junctional structure composed of both desmosomal and adherens junctional proteins.
Found in all the examined tissues including heart, brain, liver and kidney. Found at low level in lung. Expressed in dermal connective tissue, salivary gland duct and in the corneal layer (at protein level) . Expressed in arrector pili muscle (at protein level) . High levels detected in epithelial cells with lower levels found in fibroblasts and T lymphocytes .