Positive regulation of apoptosis. May facilitate FBN1 microfibril biogenesis.
Subcellular locations: Secreted, Extracellular space, Extracellular matrix
Colocalizes with FMN1 microfibrils in the eye ECM.
Expressed in colon, heart, leukocyte, liver, lung, skeletal muscle, spleen, testis and placenta. Weaker expression in bone marrow, brain tissue, kidney and pancreas. Expression studies in fetal tissues reveal strong expression in heart, kidney, liver, lung and skeletal muscle, but weaker expression in fetal brain and skin.