May play a role in intracellular immune modulation by activating NF-kappaB response and attenuating Toll-like-receptor response.
(Microbial infection) Plays an essential function in adeno-associated virus (AAV) transduction across multiple serotypes except AAV5. May play a critical role in mediating the endosomal virus escape or in the AAV virions trafficking from endosomes to the nucleus.
Subcellular locations: Golgi apparatus, Cis-Golgi network membrane, Golgi apparatus, Trans-Golgi network membrane, Golgi apparatus membrane
Colocalizes with TLR3, -7, -4, and -9.