Potassium channel subunit that does not form functional channels by itself . Can form functional heterotetrameric channels with KCNB1; this promotes a reduction in the rate of activation and inactivation of the delayed rectifier voltage-gated potassium channel KCNB1 (, ).
Subcellular locations: Cell membrane, Cytoplasm
Has to be associated with KCNB1 or possibly another partner to get inserted in the plasma membrane . Colocalizes with KCNB1 at the plasma membrane (, ). Remains intracellular in the absence of KCNB1 .
Expressed in the brain, liver, testis, small intestine, colon, thymus and adrenal gland (, ).