Catalyzes the transfer of phosphatidylinositol (PI) and phosphatidylcholine (PC) between membranes (  ). Shows a preference for PI and PC containing shorter saturated or monosaturated acyl chains at the sn-1 and sn-2 positions (, ). Preference order for PC is C16:1 > C16:0 > C18:1 > C18:0 > C20:4 and for PI is C16:1 > C16:0 > C18:1 > C18:0 > C20:4 > C20:3 .
Subcellular locations: Cytoplasm, Nucleus