Regulates ion channel activity and transmembrane ion transport. Regulates ASIC2 and ASIC3 channel activity.
Subcellular locations: Cell membrane, Cytoplasm, Cytoskeleton, Cell membrane, Membrane raft, Melanosome, Cytoplasmic vesicle
Localizes to juxtanuclear structure probably derived from the Golgi apparatus . Colocalizes with cortical actin microfilaments at small plasma membrane protrusions . Associates with alpha-granular lipid rafts . Translocates from the alpha-granular lipid rafts to the cell membrane on thrombin activation and selectively enriched in released microvesicles . Identified by mass spectrometry in melanosome fractions from stage I to stage IV .
Detected in erythrocytes (at protein level). Widely expressed.