This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity.
Subcellular locations: Golgi apparatus, Golgi stack membrane, Secreted
Membrane-bound form in trans cisternae of Golgi. Secreted into the body fluid.