RNA-binding protein involved in translationally coupled mRNA turnover (, ). Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain (, ). Required for efficient formation of stress granules .
(Microbial infection) Required for internal initiation of translation of human rhinovirus RNA.
Subcellular locations: Cytoplasm, Cytoplasm, Stress granule, Cytoplasm, P-body