Part of the CASK/TBR1/TSPYL2 transcriptional complex which modulates gene expression in response to neuronal synaptic activity, probably by facilitating nucleosome assembly. May inhibit cell proliferation by inducing p53-dependent CDKN1A expression.
Subcellular locations: Nucleus, Cytoplasm
Enriched in transcriptionally active regions of chromatin in neurons.
Ubiquitously expressed, with highest levels in brain, testis and heart, and lowest levels in liver and pancreas.