Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Serves as a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Regulates apical junction formation in bronchial epithelial cells.
Subcellular locations: Cell membrane, Cleavage furrow
Translocates to the equatorial region before furrow formation in a ECT2-dependent manner.