Functions as an activator of NF-kappa-B through increased phosphorylation of the IKK complex. May function in neuronal cells differentiation. May play a role in vesicular transport from endoplasmic reticulum to Golgi.
Subcellular locations: Golgi apparatus, Cis-Golgi network, Endoplasmic reticulum, Cytoplasm
Processes and cell bodies of neurons.
Expressed at high levels in muscle and kidney and to a lower extent in brain, heart and placenta.