DNA-binding protein that seems to act as a transcription factor . Involved in the regulation of neuronal differentiation, acts upon JNK-signaling pathway activation and plays a role in neurite outgrowth in hippocampal cells (By similarity). May mediate with FIBP FGF-signaling in the establishment of laterality in the embryo (By similarity). Promotes cell motility, seems to stimulate tumor metastasis .
Subcellular locations: Cytoplasm, Nucleus
Cytoplasmic during quiescence, translocates to the nucleus upon stimulation.
Expressed in activated T-cells (at protein level) . Expression increases in metastatic tumor cells (at protein level) .