Functions as a GTPase-activating protein (GAP) for RHOA and CDC42. Downstream partner of ARF1 which may control Golgi apparatus structure and function. Also required for CTNNA1 recruitment to adherens junctions.
Subcellular locations: Golgi apparatus membrane, Cell junction, Cytoplasmic vesicle membrane, Cytoplasm, Cytoskeleton
Localization to the Golgi is dependent on interaction with GTP-bound ARF1.
Widely expressed with higher expression in brain, heart, skeletal muscle and placenta.