Catalyzes the formation of mannose 6-phosphate (M6P) markers on high mannose type oligosaccharides in the Golgi apparatus. M6P residues are required to bind to the M6P receptors (MPR), which mediate the vesicular transport of lysosomal enzymes to the endosomal/prelysosomal compartment.
Subcellular locations: Golgi apparatus membrane
Subcellular locations: Golgi apparatus membrane
Expressed in the heart, whole brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.