Plays a role in erythroid differentiation . Involved in cell proliferation and tumor cell growth suppression . Involved in the metabolic reprogramming of cancer cells in a PDK4-dependent manner .
Subcellular locations: Mitochondrion, Mitochondrion outer membrane
Expressed in late erythroblast differentiation stages . Underexpressed in ovarian cancer epithelia cells compared with normal human ovarian surface epithelia .