Inhibits the poly(ADP-ribosyl)ation activity of PARP1 and the degradation of PARP1 by CASP3 following genotoxic stress . Binds to double-stranded RNA or DNA without sequence specificity . Involved in development of the eye and of primordial germ cells (By similarity).
Subcellular locations: Nucleus, Nucleolus, Nucleus, Nucleoplasm, Chromosome
Localizes predominantly in the nucleolus with minor punctate signals in the nucleoplasm.
Widely expressed.