May be involved in synaptic functions in the CNS.
Subcellular locations: Endoplasmic reticulum, Golgi apparatus, Cis-Golgi network, Secreted, Synapse
In the absence of CBLN1, remains in the endoplasmic reticulum/cis-Golgi apparatus. Partial secretion depends on an association with CBLN1 and maybe CBLN4, but not on CBLN2 (By similarity).