Involved in skeletal muscle development and differentiation. Regulates proliferation and differentiation of myoblasts and plays a role in myofibril assembly by promoting lateral fusion of adjacent thin fibrils into mature, wide myofibrils. Required for pseudopod elongation in transformed cells.
Subcellular locations: Cytoplasm, Cytoplasm, Cytoskeleton, Cell projection, Pseudopodium, Cell projection, Ruffle, Cytoplasm, Myofibril, Sarcomere, M line, Sarcoplasmic reticulum membrane, Endoplasmic reticulum membrane
Predominantly cytoplasmic but can colocalize with F-actin at the membrane ruffle-like structures at the tips of transformation-specific pseudopodia.
Sarcomeric muscle.