Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. Participates in signaling cascades triggered by odorant receptors via its function in cAMP biosynthesis. Required for the perception of odorants. Required for normal sperm motility and normal male fertility. Plays a role in regulating insulin levels and body fat accumulation in response to a high fat diet.
Subcellular locations: Cell membrane, Cytoplasm, Cell projection, Cilium, Golgi apparatus
Also detected in the cytoplasm, close to lipid droplets.
Detected in zona glomerulosa and zona fasciculata in the adrenal gland (at protein level) . Expressed in brain, heart, kidney, liver, lung, pancreas islets, placenta, and skeletal muscle . Detected in testis .