Key enzyme in the regulation of glycerol uptake and metabolism. Essential for male fertility and sperm mitochondrial sheath formation (By similarity). Required for proper arrangement of crescent-like mitochondria to form the mitochondrial sheath during spermatogenesis (By similarity). Can induce mitochondrial clustering through interactions with PLD6 and up-regulation of phosphatidic acid synthesis in the mitochondria .
Subcellular locations: Mitochondrion outer membrane, Cytoplasm
In sperm the majority of the enzyme is bound to mitochondria.
Testis-specific . Expressed in the midpiece of spermatozoa .