Behaves as a cytokine, promoting IL17A secretion by CD4+ T-cells, and differentiation and activation of IL17 producing helper T-cells (TH17).
Inhibitory immune receptor involved in the regulation of phagocytes.
Subcellular locations: Membrane
Subcellular locations: Secreted
Expressed on myeloid (neutrophils, eosinophils and monocytes) but not on lymphoid cells.