May play a role in triggering innate immune responses. Does not seem to play a role for any class I MHC antigen recognition.
Subcellular locations: Cell membrane
Subcellular locations: Secreted
Expressed mostly in tissues of the hematopoietic system, including bone marrow, spleen, lymph node and peripheral leukocytes. Among leukocytes, monocytes and neutrophils express the highest level. Expressed in CD14+ monocytes, but not in T-cells, B-cells or natural killer (NK) cells (at protein level).