Tumor suppressor that inhibits cell proliferation and promotes apoptosis. Modulates the activity of protein arginine N-methyltransferases, including PRMT3 and PRMT5.
Subcellular locations: Cytoplasm, Cytoskeleton, Cell junction, Cell membrane, Cytoplasm
Detected in the cytoplasm of actively dividing cells.
Expressed at high levels in brain, with lower levels in kidney, intestine, and testis. Detected in lung.