Component of adherens-type cell-cell and cell-matrix junctions . Has no phosphoglucomutase activity in vitro .
Subcellular locations: Cell junction, Adherens junction, Cytoplasm, Cytoskeleton, Cell membrane, Sarcolemma
Concentrated in focal contacts at the ends of actin bundles, and associated with actin filaments.
Detected in smooth and cardiac muscle at high levels and in skeletal muscle at low level. Present in other tissues due to vascular or other smooth muscle component. Low levels are present in liver, kidney, skin and brain (at protein level).