Essential for the organization of sarcomeric actin thin filaments in skeletal muscle . Increases the rate of actin polymerization .
Subcellular locations: Cytoplasm, Cytoplasm, Myofibril, Sarcomere, M line, Cytoplasm, Myofibril, Sarcomere, A band, Cytoplasm, Cytoskeleton
Highly expressed in nonstriated areas of developing myotubes, where it shows a granular cytoplasmic pattern. In sarcomeres, highly expressed in the M band region and, at lower levels, along actin thin filaments. Not detected in Z-disks. In sarcomeres, may be located near, but not at, actin thin filament pointed end.
Expressed in cardiac and at higher levels in skeletal muscles (at protein level).