Subcellular locations: Cell membrane, Golgi apparatus, Trans-Golgi network membrane
Cycles to the plasma membrane via endosomes in a pH sensitive manner. Associated with Rab6-positive vesicles.
Highest expression in heart, placenta, liver, pancreas and colon. Also detected in brain, lung, skeletal muscle, kidney, spleen, prostate, testis, ovary and small intestine. Lowest expression in thymus and leukocytes.