Plasma membrane-associated small GTPase specifically involved in angiogenesis ( ). Required for endothelial cell migration during vascular development via its interaction with GLUL . Elicits the formation of F-actin-rich structures, thereby regulating endothelial cell migration .
Subcellular locations: Cell membrane
Localization to the plasma membrane is regulated by GLUL.
Specifically expressed in endothelial cells in different tissues, such as brain, heart, lung and liver.