Calcium-dependent cell-adhesion protein (By similarity). May play a role in activity-induced synaptic reorganization underlying long term memory (By similarity). Could be involved in CDH2 internalization through TAOK2/p38 MAPK pathway. In hippocampal neurons, may play a role in the down-regulation of dendritic spines, maybe through its action on CDH2 endocytosis (By similarity).
Subcellular locations: Cell membrane, Cell projection, Dendrite, Presynaptic cell membrane, Postsynaptic cell membrane
Also expressed in neuronal cell bodies. Localized to excitatory, but not with inhibitory, synapses.