Could be involved in oogenesis. Involved in the regulation of endosome dynamics. Implicated in a novel signal transduction pathway, in which isoform 3 and CSK are sequentially activated by RHOD to regulate the motility of early endosomes through interactions with the actin cytoskeleton.
Subcellular locations: Cytoplasm, Cytosol, Early endosome
Isoform 3 is cytosolic but when coexpressed with RHOD, the 2 proteins colocalize to early endosomes.
Expressed in testis, ovary, small intestine, prostate, lung, liver, kidney and leukocytes.