Involved in the regulation of endocytosis and in several stages of intracellular trafficking. Plays a role in recycling endocytosed transferrin receptor and prevent its degradation. Involved in autophagosome assembly by regulating trafficking and recycling of phospholipid scramblase ATG9A.
Subcellular locations: Early endosome, Early endosome membrane
Also detected on a juxtanuclear endocytic recycling compartment (ERC).