Plays an essential role in heart function and development by regulating the organization and function of the sarcoplasmic reticulum in cardiomyocytes.
Subcellular locations: Endoplasmic reticulum membrane, Sarcoplasmic reticulum membrane
Localizes to endoplasmic reticulum tubular network . In cardiomyocytes, localizes to the junctional sarcoplasmic reticulum membrane which is closely tethered to the cell membrane and contractile machinery (By similarity).
Expressed in heart (at protein level) . Expressed in circumvallate papillae and testis .