Exhibits adenosine 5'-monophosphoramidase activity, hydrolyzing purine nucleotide phosphoramidates with a single phosphate group such as adenosine 5'monophosphoramidate (AMP-NH2) to yield AMP and NH2 (, ). Hydrolyzes adenosine 5'-O-p-nitrophenylphosphoramidate (AMP-pNA) . Hydrolyzes fluorogenic purine nucleoside tryptamine phosphoramidates in vitro . May be involved in steroid biosynthesis . May play a role in apoptosis .
Subcellular locations: Mitochondrion
High expression in liver and pancreas. Expression is significantly down-regulated in hepatocellular carcinoma (HCC) patients.