N-alpha-acetyltransferase that specifically mediates the acetylation of the N-terminal residues of histones H4 and H2A (, ). In contrast to other N-alpha-acetyltransferase, has a very specific selectivity for histones H4 and H2A N-terminus and specifically recognizes the 'Ser-Gly-Arg-Gly sequence' (, ). Acts as a negative regulator of apoptosis . May play a role in hepatic lipid metabolism (By similarity).
Subcellular locations: Cytoplasm, Nucleus
Widely expressed; with the highest expression level in liver and the lowest expression in brain (at protein level).