Involved in ligand-dependent receptor mediated endocytosis of the EGF and insulin receptors as part of the Ral signaling pathway ( ). By controlling growth factor receptors endocytosis may regulate cell survival . Through ASAP1 may regulate cell adhesion and migration .
Subcellular locations: Cytoplasm
Expressed at high levels in the cerebrum, cerebellum, lung, kidney, and testis. Weakly expressed in the kidney. Isoform 2 is down-regulated during progression of prostate cancer.