Component of the oxidative stress-induced survival signaling. May regulate the activation of SRC family protein kinases . May act as a scaffolding protein enabling SRC family protein kinases to phosphorylate and activate PI3-kinase . Binds IGF2 RNA and promotes the production of IGF2 protein .
Subcellular locations: Cytoplasm, Cell membrane
Translocates from the cytosol to plasma membrane after UV irradiation.
Widely expressed . In gastric mucosa, detected in the bottom region of the foveolar epithelium (at protein level) .