Force generating protein required for cilia beating in respiratory epithelia (, ). Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP.
Subcellular locations: Cytoplasm, Cytoskeleton, Cilium axoneme
Found in the distal portion of ciliary axoneme.
Expressed in upper and lower respiratory airway epithelia (at protein level). Not detected in spermatozoa (at protein level) .