Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity (, ). Specifically involved in tRNA repair: acts downstream of the ribosome-associated quality control (RQC) pathway by removing a 2',3'-cyclic phosphate from tRNAs following cleavage by ANKZF1 . tRNAs are then processed by TRNT1 .
Subcellular locations: Cytoplasm, Cytosol, Nucleus
Mainly cytosolic.
Widely expressed . Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas .