Involved in the fragmentation of the mitochondrial network and its perinuclear clustering ( , ). Plays a minor role in the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface and mitochondrial fission (  ). May not be essential for the assembly of functional fission complexes and the subsequent membrane scission event (, ). Also mediates peroxisomal fission . May act when the products of fission are directed toward mitochondrial homeostasis, mitophagy, or apoptosis . Can induce cytochrome c release from the mitochondrion to the cytosol, ultimately leading to apoptosis .
Subcellular locations: Mitochondrion outer membrane, Peroxisome membrane