Regulator which is able to repress transcription, possibly via its interaction with a multiprotein chromatin remodeling complex that modifies the chromatin . Its interaction with BRCA2 suggests that it may play a central role in the DNA repair function of BRCA2 . Mediates ligand-dependent transcriptional activation by nuclear hormone receptors .
Subcellular locations: Nucleus
Localizes to DNA damage markers in irradiated cells, suggesting that it participates in DNA repair process.