Membrane receptor that binds the K-D-E-L sequence motif in the C-terminal part of endoplasmic reticulum resident proteins and maintains their localization in that compartment by participating to their vesicle-mediated recycling back from the Golgi ( ). Binding is pH dependent, and is optimal at pH 5-5.4 (By similarity).
Subcellular locations: Endoplasmic reticulum membrane, Golgi apparatus membrane, Cytoplasmic vesicle, COPI-coated vesicle membrane
Localized in the Golgi in the absence of bound proteins with the sequence motif K-D-E-L. Trafficks back to the endoplasmic reticulum together with cargo proteins containing the sequence motif K-D-E-L.