Endoplasmic reticulum (ER)-shaping membrane protein that plays a role in determining ER morphology . Involved in the stabilization of nascent three-way ER tubular junctions within the ER network ( , ). May also play a role as a curvature-stabilizing protein within the three-way ER tubular junction network . May be involved in limb development (By similarity). Is involved in central nervous system development .
Subcellular locations: Endoplasmic reticulum membrane
Localizes at endoplasmic reticulum (ER) three-way tubular junctions, which represent crossing-points at which the tubules build a polygonal network (  ).
Expressed in neural precursor cells, where it is detected at the growth-cone-like structure and branching sites of neurite-like processes.