May play a role as a localized scaffold for the assembly of a multiprotein signaling complex and as mediator of the trafficking of its binding partners at specific subcellular location in neurons . Through complex formation with NSG1, GRIA2 and STX12 controls the intracellular fate of AMPAR and the endosomal sorting of the GRIA2 subunit toward recycling and membrane targeting (By similarity).
Subcellular locations: Cytoplasmic vesicle, Perikaryon, Cell projection, Dendrite, Cytoplasm, Endomembrane system, Postsynaptic cell membrane, Postsynaptic density, Endoplasmic reticulum membrane
Membrane-associated with vesicles, peri-Golgi complexes and endoplasmic reticulum. Enriched in postsynaptic plasma membrane and postsynaptic densities.