Transcription factor which acts as both an activator and a repressor . Activates transcription of a number of genes including the heat shock chaperones HSPA1A and HSPA6 and the antioxidant NADPH-dependent reductase DHRS2 which are involved in protection against oxidative stress . Required for normal brain development (By similarity).
Subcellular locations: Nucleus, Cytoplasm, Cytoplasm, Perinuclear region
Localizes to the nucleus and cytoplasm with higher levels in the nucleus where it is expressed in a diffuse manner . Located in the cytoplasm of spermatocytes and strongly accumulates at the perinuclear region in elongated spermatids .
Expressed in testis (at protein level).