Transcription factor that binds specifically to the RAS-responsive elements (RRE) of gene promoters (  ). Represses the angiotensinogen gene . Negatively regulates the transcriptional activity of AR . Potentiates the transcriptional activity of NEUROD1 . Promotes brown adipocyte differentiation (By similarity). May be involved in Ras/Raf-mediated cell differentiation by enhancing calcitonin expression .
Subcellular locations: Nucleus speckle
Expressed in heart, placenta, lung, liver, skeletal muscle, kidney and pancreas. Not found in the brain.