Stabilizes microtubules and may regulate actin fiber dynamics through the activation of Rho family GTPases . May also function in Wnt signaling by promoting the rapid degradation of CTNNB1 ( ).
Subcellular locations: Cytoplasm, Cytoskeleton, Golgi apparatus, Cytoplasm, Cytoplasm, Perinuclear region
Associated with actin filaments (, ). Associated with microtubule network ( ).
Widely expressed (at protein level). Specifically expressed in the CNS.