This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Represses transcription from promoters with ATF sites. It may repress transcription by stabilizing the binding of inhibitory cofactors at the promoter.
Activates transcription presumably by sequestering inhibitory cofactors away from the promoters.
Stress-induced isoform, counteracts the transcriptional repression of isoform 1.
Subcellular locations: Nucleus