Mitochondrial proton-coupled zinc ion antiporter mediating the export of zinc from the mitochondria and involved in zinc homeostasis, zinc mobilization as well as mitochondrial morphology and health (By similarity). In nucleus, functions as a secondary coactivator for nuclear receptors by cooperating with p160 coactivators subtypes. Plays a role in transcriptional activation of Wnt-responsive genes (By similarity).
Subcellular locations: Mitochondrion membrane, Nucleus, Endoplasmic reticulum
Partial co-localization with endoplasmic reticulum. Linked to mitochondrial ribosomes.