Proton-dependent transporter of monocarboxylates such as L-lactate and pyruvate ( ). Plays a predominant role in L-lactate efflux from highly glycolytic cells (By similarity).
Subcellular locations: Cell membrane, Basolateral cell membrane
Plasma membrane localization is dependent upon the BSG/MCT4 interaction . Basolateral sorting signals (BLSS) in C-terminal cytoplasmic tail ensure its basolateral expression in polarised epithelial cells .
Highly expressed in skeletal muscle.