Probably involved in the organization of the actin cytoskeleton by acting downstream of CDC42, inducing actin filament assembly. Alters CDC42-induced cell shape changes. In activated T-cells, may play a role in CDC42-mediated F-actin accumulation at the immunological synapse. May play a role in early contractile events in phagocytosis in macrophages (By similarity).
Subcellular locations: Cytoplasm, Cytoskeleton, Cell membrane, Cell projection, Phagocytic cup
Recruited to the activated TCR prior actin polymerization. Localizes at the phagocytic cup of macrophages.