Required for proper contractility of visceral smooth muscle cells . Mediates nucleation of actin filaments.
Subcellular locations: Cytoplasm, Myofibril, Sarcomere, Cytoplasm, Cytoskeleton
Colocalizes with actin filaments in sarcomeres.
Detected in lung vascular smooth muscle (at protein level) . Detected in thyroid and extraocular smooth muscle, but not skeletal muscle . Detected in heart, aorta, skeletal muscle, colon, urinary bladder, uterus, stomach, and small intestine .