Transcription cofactor . Negatively regulates transcription activation by catenin beta-1 CTNNB1, perhaps acting by competing with TCF4 for CTNNB1 binding . May play a role in DNA-damage response signaling . Binds specifically to DNA sequences at peri-centromeric chromatin loci.
Subcellular locations: Nucleus, Chromosome, Centromere
Localized to peri-centromeric, H3K9me3-marked heterochromatin.