RTD-1 and RTD-3 have similar antimicrobial activities against the Gram-positive bacteria S.aureus 502A and L.monocytogenes, the Gram-negative bacteria S.typhimurium and E.coli ML35, and the fungi C.albicans 16820 and C.neoformans 271A.
RTD-1 is expressed in bone marrow. Detected in promyelocytes, myelocytes and mature neutrophils and monocytes.