Hydrolyzes lysoglycerophospholipids to produce lysophosphatidic acid (LPA) and the corresponding amines (, ). Shows a preference for 1-O-alkyl-sn-glycero-3-phosphocholine (lyso-PAF), lysophosphatidylethanolamine (lyso-PE) and lysophosphatidylcholine (lyso-PC) (, ). May be involved in bioactive N-acylethanolamine biosynthesis from both N-acyl-lysoplasmenylethanolamin (N-acyl-lysoPlsEt) and N-acyl-lysophosphatidylethanolamin (N-acyl-lysoPE) (, ). In addition, hydrolyzes glycerophospho-N-acylethanolamine to N-acylethanolamine . Does not display glycerophosphodiester phosphodiesterase activity, since it cannot hydrolyze either glycerophosphoinositol or glycerophosphocholine (By similarity).
Subcellular locations: Cytoplasm, Membrane, Cytoplasm, Perinuclear region, Endoplasmic reticulum
Concentrated at the perinuclear region and the cell periphery .
Widely expressed with high expression level in testis.