Adapter protein required for Golgi and endoplasmic reticulum biogenesis . Involved in Golgi and endoplasmic reticulum maintenance during interphase and in their reassembly at the end of mitosis . The complex formed with VCP has membrane fusion activity; membrane fusion activity requires USO1-GOLGA2 tethering and BET1L . VCPIP1 is also required, but not its deubiquitinating activity . Together with NSFL1C/p47, regulates the centrosomal levels of kinase AURKA/Aurora A during mitotic progression by promoting AURKA removal from centrosomes in prophase . Also, regulates spindle orientation during mitosis .
Subcellular locations: Nucleus, Cytoplasm, Cytosol, Endoplasmic reticulum, Golgi apparatus, Cytoplasm, Cytoskeleton, Microtubule organizing center, Centrosome
Localizes to centrosome during mitotic prophase and metaphase.