May be involved in redox reactions associated with the formation of disulfide bonds (By similarity). May contribute to the quality control of protein folding in the endoplasmic reticulum . May regulate protein folding by enhancing the catalytic activity of UGGT1/UGCGL1 and UGGT2/UGCGL2 .
Subcellular locations: Endoplasmic reticulum lumen
The association with UGGT1/UGCGL1 is essential for its retention in the endoplasmic reticulum.
Higher levels in prostate and thyroid gland.