It is involved in synaptogenesis and promotes excitatory synapse differentiation ( ). Suppresses neurite outgrowth (By similarity). Involved in the negative regulation of NTRK2 .
Subcellular locations: Membrane, Cell membrane, Cell projection, Dendrite
Expressed predominantly in the cerebral cortex of the brain but also at low levels in the spinal cord and medulla. Also expressed in some astrocytic brain tumors such as astrocytomas, oligodendrogliomas, glioblastomas, gangliogliomas and primitive neuroectodermal tumors.