Function as phospholipase selective for phosphatidylcholine ( ). Implicated as a critical step in numerous cellular pathways, including signal transduction, membrane trafficking, and the regulation of mitosis. May be involved in the regulation of perinuclear intravesicular membrane traffic (By similarity).
Subcellular locations: Cytoplasm, Perinuclear region, Endoplasmic reticulum membrane, Golgi apparatus membrane, Late endosome membrane
Expressed abundantly in the pancreas and heart and at high levels in brain, placenta, spleen, uterus and small intestine.