Calcium-dependent phospholipid-binding protein that plays a role in calcium-mediated intracellular processes. Binds phospholipid membranes in a calcium-dependent manner (By similarity). Plays a role in dendrite formation by melanocytes .
Subcellular locations: Cytoplasm, Cell membrane, Endosome, Cytoplasmic vesicle, Clathrin-coated vesicle, Perikaryon, Cell projection, Dendrite
Mainly cytoplasmic in absence of calcium. Associated predominantly with membranes in presence of calcium. Translocates to the cell membrane in a calcium-dependent manner. Colocalized with transferrin in intracellular clathrin-coated membrane vesicles in a calcium-dependent manner.
Widely expressed in the brain ( ). Expressed weakly in the kidney, liver and fetal heart . Expressed in melanocytes .