Component of the centralspindlin complex that serves as a microtubule-dependent and Rho-mediated signaling required for the myosin contractile ring formation during the cell cycle cytokinesis. Essential for cytokinesis in Rho-mediated signaling. Required for the localization of ECT2 to the central spindle. Plus-end-directed motor enzyme that moves antiparallel microtubules in vitro.
Subcellular locations: Nucleus, Cytoplasm, Cytoskeleton, Spindle, Midbody, Midbody ring
Localizes to the interzone of mitotic spindles. Detected at the midbody during later stages of mitotic cytokinesis.
Widely expressed.