May play a role in development of the periodontium which surrounds and supports the teeth by promoting the differentiation of multi-potent cells from the periodontal ligament into cementoblasts to form the cementum ( ). Binds hydroxyapatite and may promote the biomineralization of the cementum . Also promotes cell proliferation ( ).
Subcellular locations: Cytoplasm, Nucleus
Localizes to the nucleus of some cementoblasts.
Expressed by cementoblasts, a subpopulation of periodontal ligament cells and cells located around vessels in periodontium (at protein level).