Plays an essential role in neuronal cell migration.
Subcellular locations: Cytoplasm, Cytoskeleton, Microtubule organizing center, Centrosome
Localized specifically to the pericentriolar region.
Isoform 1 and isoform 4 are expressed in spleen, lymph, thymus, tonsil and peripheral blood leukocytes, with isoform 1 expressed at higher levels. Isoform 4 is detected in K-562 leukemia cells and in the blood of precursor T lymphoblastic lymphoma (T-ALL) patients.