Chromatin-associated factor that regulates transcription . Regulates Pol I-mediated rRNA biogenesis and, probably, Pol III-mediated transcription . Regulates the epigenetic status of rDNA .
Subcellular locations: Nucleus, Nucleus, Nucleolus, Chromosome
Associates with chromatin regions of rDNA.
High levels seen in the placenta, skeletal muscle, kidney and pancreas while lower levels were seen in the heart, brain and lung.