Positive effector of the Wnt signaling pathway; activates WNT3A signaling via DVL2. Regulates JNK activation by AXIN1 and DVL2.
Subcellular locations: Cell junction, Focal adhesion, Cytoplasm, Cytoskeleton, Stress fiber, Cytoplasm
Colocalizes with gamma-tubulin at the centrosome, both during interphase and mitosis . Associated with actin stress fiber at the filament ends .
Subcellular locations: Cytoplasm
Not associated with stress fibers.
Ubiquitously expressed with higher expression in cardiac and skeletal muscles.