Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. Involved in TLR3 trafficking .
Subcellular locations: Golgi apparatus, Cytoplasmic vesicle membrane, Membrane, Clathrin-coated pit
Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex.
Widely expressed.