Part of the CASK/TBR1/TSPYL2 transcriptional complex which modulates gene expression in response to neuronal synaptic activity, probably by facilitating nucleosome assembly. May inhibit cell proliferation by inducing p53-dependent CDKN1A expression (By similarity).
Subcellular locations: Nucleus, Cytoplasm
Enriched in transcriptionally active regions of chromatin in neurons.
Ubiquitously expressed, with highest levels in testis, adrenal gland, cerebral cortex, ovary, skeletal muscle and spleen. Present in testis, adrenal gland, cerebral cortex and ovary (at protein level).