Transcription regulator specifically required for multiciliate cell differentiation . Acts in a multiprotein complex containing E2F4 and E2F5 that binds and activates genes required for centriole biogenesis. Required for the deuterosome-mediated acentriolar pathway . Plays a role in mitotic cell cycle progression by promoting cell cycle exit. Modulates GMNN activity by reducing its affinity for CDT1 (, ).
Subcellular locations: Nucleus
Excluded from the nucleolus.