Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme . Important for proper ciliary and flagellar beating. May act in cooperation with CFAP45 and axonemal dynein subunit DNAH11 . May play a role in cell growth and/or survival .
Subcellular locations: Cytoplasm, Cell projection, Cilium, Flagellum, Cytoplasm, Cytoskeleton, Cilium axoneme
Located in the proximal region of respiratory cilia.
Expressed in respiratory cells and sperm (at protein level) (, ). Highly expressed in testis . Up-regulated in hepatocellular carcinoma (HCC) .