May constitute a control point in macrophage inflammatory response, promoting LPS-induced TLR4-mediated TNF production . Determines the threshold for activation of B cells by low-affinity and low-avidity ligands via PLCG2 activation and its downstream pathways (By similarity).
Subcellular locations: Nucleus, Cytoplasm
Expressed in different endometrial adenocarcinoma cell lines and various other cell lines apart from the prostate cell line LNCaP and the ovarian cancer cell line BG1.