N-alpha-acetyltransferase that specifically mediates the acetylation of N-terminal residues of the transmembrane proteins, with a strong preference for N-termini facing the cytosol . Displays N-terminal acetyltransferase activity towards a range of N-terminal sequences including those starting with Met-Lys, Met-Val, Met-Ala and Met-Met ( , ). Required for normal chromosomal segregation during anaphase . May also show histone acetyltransferase activity; such results are however unclear in vivo and would require additional experimental evidences .
Subcellular locations: Golgi apparatus membrane
Probably forms an intramembrane hairpin-like structure in the membrane.