Essential for the control of the cell cycle at the late G1 and early S phase.
Subcellular locations: Nucleus
According to , highest levels of expression in adult testis, thymus and brain. Lower levels in placenta, spleen and colon. Consistently elevated levels in tumor-derived cells compared to non-transformed proliferating cells. According to : low levels in thymus, prostate, brain, skeletal muscle, and kidney. Elevated levels in lung. According to  highly expressed in testis, placenta, thymus and brain. In a lesser extent in small intestine and colon.