Plays an essential role in the survival of diffuse-type gastric cancer cells. Acts as a nucleolar anchoring protein for DDX47. May be involved in regulation of gene expression at the post-transcriptional level or in ribosome biogenesis in cancer cells.
Subcellular locations: Nucleus, Nucleolus
Localizes in the nucleolar-organizing region during ribosome biogenesis.
Expressed in various diffuse-type gastric cancers. Detected at lower levels in skeletal muscle.