Cofactor for the transcription factor TCF7 . Involved in regulation of lymphoid development by driving multipotent hematopoietic progenitor cells towards a T cell fate .
Subcellular locations: Nucleus, Cytoplasm, Cytoplasm, Cytoskeleton, Microtubule organizing center, Centrosome
Continuous nuclear export is followed by degradation.
Expressed in myoepithelial cells of normal breast tissue (at protein level) . Highly expressed in thymus . Expressed in colon, small intestine, prostate and ovary. Not detected in peripheral blood lymphocytes and spleen .