Unlike the other SLC37 members, lacks glucose-6-phosphate antiporter activity . In osteoclasts, forms a transporter complex with ATRAID for nitrogen-containing-bisphophonates (N-BPs) required for releasing N-BP molecules that have trafficked to lysosomes through fluid-phase endocytosis into the cytosol .
Subcellular locations: Endoplasmic reticulum membrane, Lysosome membrane
Expressed in liver, kidney, intestine and pancreas.