Involved in the regulation of endocytosis and in several stages of intracellular trafficking ( , ). Plays a role in recycling endocytosed transferrin receptor and prevent its degradation . Involved in autophagosome assembly by regulating trafficking and recycling of phospholipid scramblase ATG9A (, ).
Subcellular locations: Early endosome membrane
Also detected on a juxtanuclear endocytic recycling compartment (ERC).