Receptor for C-C type chemokine. Binds and responds to a variety of chemokines, including CCL11, CCL26, CCL7, CCL13, RANTES(CCL5) and CCL15 ( ). Subsequently transduces a signal by increasing the intracellular calcium ions level . In addition acts as a possible functional receptor for NARS1 .
(Microbial infection) Alternative coreceptor with CD4 for HIV-1 infection.
Subcellular locations: Cell membrane
In eosinophils as well as trace amounts in neutrophils and monocytes.