One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
Subcellular locations: Cell membrane, Cell junction, Gap junction
CNS specific. Expression is restricted to brain, spinal cord, and sciatic nerve. According to , expression is abundant in skeletal muscle, liver, and heart, and to a minor degree in pancreas and kidney.