Orphan receptor involved in vision (, ). Required for signal transduction through retinal depolarizing bipolar cells . Acts as an atypical G-protein coupled receptor that recruits and regulates the R7 group RGS-GNB5 complexes instead of activating G proteins: promotes the GTPase activator activity of R7 RGS proteins, increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form (By similarity). Associates with components of metabotropic signaling cascade in retina ON-bipolar neurons, such as TRPM1 and GRM6: may control the ability of the GRM6 cascade to gate TRPM1 (By similarity).
Subcellular locations: Cell membrane, Postsynaptic cell membrane, Cell projection, Dendrite
Specifically localizes to the tips of retinal ON-bipolar dendrites.
Expressed in the retina.