Chromatin reader component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4 ( ). YEATS2 specifically recognizes and binds histone H3 crotonylated at 'Lys-27' (H3K27cr) . Crotonylation marks active promoters and enhancers and confers resistance to transcriptional repressors .
Subcellular locations: Nucleus