Functions as a guanine nucleotide exchange factor for RAC1. May play a role in semaphorin signaling. Plays a role in the assembly and disassembly of dendritic filopodia, the formation of dendritic spines, regulation of dendrite length and ultimately the formation of synapses (By similarity).
Subcellular locations: Cell membrane, Synapse, Synapse, Synaptosome, Cytoplasm, Cytosol, Cell projection, Filopodium, Cell projection, Dendrite, Cell projection, Dendritic spine
Recruited to the cell membrane via interaction with CADM1.
Detected in cAMP-treated chondrocytes, but not in untreated chondrocytes. Detected in fetal brain, heart and spleen, and in adult testis, kidney and lung.