Single-stranded nucleic acid binding protein that binds preferentially to oligo dC ( , ). Together with PCBP2, required for erythropoiesis, possibly by regulating mRNA splicing (By similarity).
(Microbial infection) In case of infection by poliovirus, plays a role in initiation of viral RNA replication in concert with the viral protein 3CD.
Subcellular locations: Nucleus, Cytoplasm
Loosely bound in the nucleus . May shuttle between the nucleus and the cytoplasm .
Abundantly expressed in skeletal muscle, thymus and peripheral blood leukocytes while a lower expression is observed in prostate, spleen, testis, ovary, small intestine, heart, liver, adrenal and thyroid glands.