Probable ligand for integrin in the brain. This is a non catalytic metalloprotease-like protein . Involved in regulation of cell adhesion and spreading and in inhibition of cell proliferation. Neuronal receptor for LGI1.
Subcellular locations: Cell membrane, Cell projection, Axon
Highly expressed in the brain and in some high-grade but not low-grade gliomas. Detected slightly or not at all in other tissues.