Mediates the transfer of lipids between membranes at organelle contact sites (By similarity). Required for the formation or stabilization of ER-mitochondria contact sites which enable transfer of lipids between the ER and mitochondria (By similarity). Negatively regulates lipid droplet size and motility (By similarity). Required for efficient lysosomal protein degradation (By similarity).
Subcellular locations: Mitochondrion outer membrane, Endoplasmic reticulum membrane, Endosome membrane, Lysosome membrane, Lipid droplet, Golgi apparatus, Cytoplasmic vesicle, Secretory vesicle, Neuronal dense core vesicle
Localizes at mitochondria-endosomes and mitochondria-endoplasmic reticulum contact sites.