Growth factor for endothelial cells. VEGF-B167 binds heparin and neuropilin-1 whereas the binding to neuropilin-1 of VEGF-B186 is regulated by proteolysis.
Subcellular locations: Secreted
Secreted but remains associated to cells or to the extracellular matrix unless released by heparin.
Expressed in all tissues except liver. Highest levels found in heart, skeletal muscle and pancreas.