Mitochondrial phosphoenolpyruvate carboxykinase that catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle . Can play an active role in glyceroneogenesis and gluconeogenesis .
Subcellular locations: Mitochondrion
Widely expressed.