Increases the transcriptional activity of NFKB1 by facilitating its nuclear translocation, DNA-binding and associated apoptotic response, when overexpressed. May sequester WWOX in lysosomal vesicles and thereby regulate WWOX role as tumor suppressor.
Subcellular locations: Cytoplasmic vesicle membrane, Late endosome membrane, Lysosome membrane
When overexpressed, localizes in the nucleus and perinuclear regions.