Probably plays a role in the control of regulated secretion in neural and endocrine cells.
(Microbial infection) Receptor for the C.botulinum neurotoxin type A2 (BoNT/A, botA); glycosylation is not essential but enhances the interaction . Probably also serves as a receptor for the closely related C.botulinum neurotoxin type A1.
Subcellular locations: Cytoplasmic vesicle, Secretory vesicle, Synaptic vesicle membrane, Cytoplasmic vesicle, Secretory vesicle, Acrosome
Associated with synaptic-like microvesicles but not with insulin-containing vesicles in insulin-secreting cells of the pancreas (By similarity). Localizes to microvesicles in the pinealocytes. Localizes to the acrosome in spermatids (By similarity).