Choline transporter that plays a role in the choline-acetylcholine system and is required to the efferent innervation of hair cells in the olivocochlear bundle for the maintenance of physiological function of outer hair cells and the protection of hair cells from acoustic injury (By similarity) (, ). Also described as a thiamine pyrophosphate transporter in colon, may mediate the absorption of microbiota-generated thiamine pyrophosphate and contribute to host thiamine (vitamin B1) homeostasis (, ).
Has also thiamine pyrophosphate transporter activity.
Subcellular locations: Membrane, Apical cell membrane
Highly expressed in colon, also detected in prostate, trachea and lung . Isoform 3 is also expressed in colon but a lower levels .
Expressed in colon at low levels.