Tube-forming lipid transport protein which provides phosphatidylethanolamine for glycosylphosphatidylinositol (GPI) anchor synthesis in the endoplasmic reticulum (Probable). Plays a role in endosomal trafficking and endosome recycling. Also involved in the actin cytoskeleton and cilia structural dynamics . Acts as a regulator of phagocytosis .
Subcellular locations: Cell membrane, Endoplasmic reticulum membrane, Mitochondrion membrane
Localizes to endoplasmic reticulum-cell membrane and some endoplasmic reticulum-mitochondria contact sites.
Highly expressed in testis and ovary. Weakly or not expressed in other tissues.