Plays a role in the regulation of diverse cellular processes such as ribosome biogenesis, chromatin remodeling or protein chaperoning (, ). Modulates the histone chaperone function and the RNA-binding activity of nucleolar phosphoprotein B23/NPM . Efficiently mediates chromatin remodeling when included in a pentamer containing NPM3 and NPM .
Subcellular locations: Nucleus, Nucleus, Nucleolus
Mainly found in the granular component of the nucleolus.
Ubiquitous.