Involved in ciliogenesis . It is required for appropriate acetylation and polyglutamylation of ciliary microtubules, and regulation of cilium length . Interacts with microtubules and promotes microtubule polymerization via its HEAT repeat domains, especially those in TOG region 2 and 4 (By similarity).
Subcellular locations: Cell projection, Cilium, Cytoplasm, Cytoskeleton, Cytoplasm, Cytoskeleton, Cilium axoneme
Detected along the length of primary cilia and at the basal body. Colocalization with the cytoplasmic microtubule cytoskeleton upon heterologous expression is most likely an artifact.