Involved in pre-60S ribosomal particles maturation by promoting the nuclear export of the 60S ribosome . Negatively modulates the DNA binding activity of Oct-2 and therefore its transcriptional regulatory activity .
Subcellular locations: Nucleus, Nucleolus, Cytoplasm
Shuttles between the nucleus and the cytoplasm.
Ubiquitous. Detected in spleen, prostate, testis, small intestine, colon and to a minor level in thymus and peripheral blood leukocytes.