Transcriptional regulator that binds the cAMP response element (CRE), a sequence present in many viral and cellular promoters. Isoforms are either transcriptional activators or repressors. Plays a role in spermatogenesis and is involved in spermatid maturation .
May play a role in the regulation of the circadian clock: acts as a transcriptional repressor of the core circadian component PER1 by directly binding to cAMP response elements in its promoter.
Subcellular locations: Nucleus
Subcellular locations: Cytoplasm, Nucleus
Expressed in testes (round spermatids) (at protein level). Isoform 14 is the major activator form in testes.