Exhibits both phospholipase A1/2 and acyltransferase activities (, ). Shows phospholipase A1 (PLA1) and A2 (PLA2) activity, catalyzing the calcium-independent release of fatty acids from the sn-1 or sn-2 position of glycerophospholipids ( ). Shows O-acyltransferase activity, catalyzing the transfer of a fatty acyl group from glycerophospholipid to the hydroxyl group of lysophospholipid . Shows N-acyltransferase activity, catalyzing the calcium-independent transfer of a fatty acyl group at the sn-1 position of phosphatidylcholine (PC) and other glycerophospholipids to the primary amine of phosphatidylethanolamine (PE), forming N-acylphosphatidylethanolamine (NAPE) which serves as precursor for N-acylethanolamines (NAEs) ( ).
Subcellular locations: Membrane, Cytoplasm
Subcellular locations: Nucleus, Cytoplasm
Abundantly expressed in testis, skeletal muscle, brain, and heart.
Highly expressed in the testis, skeletal muscle, brain, heart, and thyroid.