Seems to be involved in cell adhesion through trans-homophilic and -heterophilic interactions, the latter including specifically interactions with NECTIN1. Does not act as receptor for alpha-herpesvirus entry into cells.
(Microbial infection) Acts as a receptor for measles virus.
Subcellular locations: Cell membrane, Cell junction, Adherens junction
Colocalizes with AFDN at cadherin-based adherens junctions .
Subcellular locations: Secreted
The secreted form is found in breast tumor patients .
Predominantly expressed in placenta. Not detected in normal breast epithelium but expressed in breast carcinoma.