Microtubule-binding protein required for ciliogenesis . May function in ciliogenesis by mediating the transport of proteins like BBS4 to the cilium, but also through the organization of the centriolar satellites . Plays a role in retina morphogenesis and/or homeostasis (By similarity).
Subcellular locations: Cytoplasm, Cytoskeleton, Microtubule organizing center, Centrosome, Cytoplasm, Cytoskeleton, Microtubule organizing center, Centrosome, Centriolar satellite, Cell projection, Cilium, Cytoplasm, Cytoskeleton, Cilium basal body, Photoreceptor inner segment, Cell projection, Cilium, Photoreceptor outer segment
Restricted to the centrosomes and the spindle microtubules during mitosis . Enriched in the inner segment of the photoreceptor .
Widely expressed (at protein level) . Expressed in retina, mainly in photoreceptors but also in outer plexiform and ganglion cell layers (at protein level) .