Plays an important role in maintenance of mitochondrial morphology and in mediating either calcium or potassium/proton antiport (   , ). Mediates proton-dependent calcium efflux from mitochondrion ( ). Functions also as an electroneutral mitochondrial proton/potassium exchanger ( ). Crucial for the maintenance of mitochondrial tubular networks and for the assembly of the supercomplexes of the respiratory chain (, ). Required for the maintenance of the tubular shape and cristae organization (, ).
Subcellular locations: Mitochondrion inner membrane