Required for assembly of dynein regulatory complex (DRC) and inner dynein arm (IDA) complexes, which are responsible for ciliary beat regulation, thereby playing a central role in motility in cilia and flagella . Probably acts together with CCDC40 to form a molecular ruler that determines the 96 nanometer (nm) repeat length and arrangements of components in cilia and flagella (By similarity). Not required for outer dynein arm complexes assembly .
Subcellular locations: Cytoplasm, Cytoskeleton, Cilium axoneme
CCDC40 is required for localization to axonemes.
Mainly expressed in nasal brushings and, to a lesser extent, in lungs and testis.