Plays an essential role in facilitating the proper assembly of the mitochondrial large ribosomal subunit and its helicase activity is essential for this function (, ). May be involved in RNA processing or transport. Has RNA and Mg(2+)-dependent ATPase activity .
Subcellular locations: Nucleus, Mitochondrion, Mitochondrion matrix, Mitochondrion nucleoid, Mitochondrion matrix
Transported between these two compartments. Nuclear localization depends on active RNA polymerase II transcription. Localizes to mitochondrial RNA granules found in close proximity to the mitochondrial nucleoids.
Expressed in all tissues tested, including brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, leukocytes, colon, small intestine, ovary and prostate.