Catalyzes the interconversion between carbon dioxide and water and the dissociated ions of carbonic acid (i.e. bicarbonate and hydrogen ions).
Subcellular locations: Nucleus, Nucleus, Nucleolus, Cell membrane, Cell projection, Microvillus membrane
Found on the surface microvilli and in the nucleus, particularly in nucleolus.
Expressed primarily in carcinoma cells lines. Expression is restricted to very few normal tissues and the most abundant expression is found in the epithelial cells of gastric mucosa.