Ketosamine-3-kinase involved in protein deglycation by mediating phosphorylation of ribuloselysine and psicoselysine on glycated proteins, to generate ribuloselysine-3 phosphate and psicoselysine-3 phosphate, respectively (, ). Ribuloselysine-3 phosphate and psicoselysine-3 phosphate adducts are unstable and decompose under physiological conditions (, ). Not able to phosphorylate fructoselysine .
Widely expressed; except in skeletal muscle where it is expressed at very low level . Expressed in erythrocytes .