This is a non-secretory ribonuclease. It is a pyrimidine specific nuclease with a slight preference for U. Cytotoxin and helminthotoxin. Selectively chemotactic for dendritic cells. Possesses a wide variety of biological activities.
Subcellular locations: Lysosome, Cytoplasmic granule
Matrix of eosinophil's large specific granule.
Liver, lung, spleen, leukocytes and body fluids.