Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Associates with KCNQ1/KVLTQ1 and inhibits potassium currents.
May inhibit KCNQ4-mediated potassium currents.
Subcellular locations: Membrane
Predominantly expressed in embryo and adult uterus. Low expression found in kidney, small intestine, lung and heart.
Detected in kidney, thymus, and uterus (at protein level).