Cyclin which controls both the G1/S and the G2/M transition phases of the cell cycle. Functions through the formation of specific serine/threonine protein kinase holoenzyme complexes with the cyclin-dependent protein kinases CDK1 or CDK2. The cyclin subunit confers the substrate specificity of these complexes and differentially interacts with and activates CDK1 and CDK2 throughout the cell cycle.
Subcellular locations: Nucleus, Cytoplasm
Exclusively nuclear during interphase . Detected in the nucleus and the cytoplasm at prophase . Cytoplasmic when associated with SCAPER .