Stimulator of protein export for NES-containing proteins . Also plays a role in the nuclear export of U1 snRNA, tRNA, and mRNA . The NXF1-NXT1 heterodimer is involved in the export of HSP70 mRNA in conjunction with ALYREF/THOC4 and THOC5 (, ).
Subcellular locations: Nucleus, Nucleus speckle, Cytoplasm
Shuttles between the nucleus and the cytoplasm.