Enzyme which catalyzes the acetylation of polyamines ( ). Substrate specificity: norspermidine = spermidine >> spermine > N(1)-acetylspermine . This highly regulated enzyme allows a fine attenuation of the intracellular concentration of polyamines . Also involved in the regulation of polyamine transport out of cells . Also acts on 1,3-diaminopropane and 1,5-diaminopentane (, ).
Subcellular locations: Cytoplasm, Cytosol