Rab effector involved in protein trafficking from apical recycling endosomes to the apical plasma membrane. Involved in insulin granule exocytosis. May regulate V-ATPase intracellular transport in response to extracellular acidosis.
Subcellular locations: Cytoplasm, Recycling endosome membrane, Early endosome membrane, Golgi apparatus membrane, Cytoplasmic vesicle, Secretory vesicle membrane, Mitochondrion membrane
Detected at low levels in heart, brain, placenta, lung, liver, adipocytes, kidney, spleen, skeletal muscle and pancreas.