Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE).
Subcellular locations: Nucleus, Cytoplasm
Expressed in aortic endothelial cells (at protein level) . Expressed in monocytes . Expressed in a variety of tumor cell lines.