Zinc phosphodiesterase, which displays mitochondrial tRNA 3'-processing endonuclease activity. Involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA . Associates with mitochondrial DNA complexes at the nucleoids to initiate RNA processing and ribosome assembly .
Subcellular locations: Mitochondrion, Mitochondrion matrix, Mitochondrion nucleoid, Nucleus
Mainly mitochondrial.
Widely expressed. Highly expressed in heart, placenta, liver, skeletal muscle, kidney, pancreas, testis and ovary. Weakly expressed in brain, lung, spleen, thymus, prostate, small intestine, colon and leukocytes.