Force generating protein component of the outer dynein arms (ODAs) in the sperm flagellum. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly.
Subcellular locations: Cytoplasm, Cytoskeleton, Flagellum axoneme, Cytoplasm
Detected in sperm tail, with almost exclusive localization to the principal piece. Also detected in the cytoplasm of primary spermatocytes.
Expressed in spermatozoa (at protein level). Not detected in airway epithelial cells (at protein level).