Motor for anterograde transport of mitochondria. Has a microtubule plus end-directed motility. Isoform 2 is required for induction of neuronal apoptosis.
Isoform 1 mediates the transport of synaptic vesicles in neuronal cells.
Subcellular locations: Cytoplasm, Cytoskeleton, Mitochondrion, Cell projection, Axon
Subcellular locations: Cytoplasmic vesicle, Secretory vesicle, Synaptic vesicle
Isoform 3 is abundant in the skeletal muscle. It is also expressed in fetal brain, lung and kidney, and adult heart, placenta, testis, ovary and small intestine. Isoform 2 is abundant in the brain and also expressed in fetal heart, lung, liver and kidney, and adult skeletal muscle, placenta, liver, kidney, heart, spleen, thymus, prostate, testis, ovary, small intestine, colon and pancreas.