Basement membrane-associated chondroitin sulfate proteoglycan (CSPG). Has prolyl 3-hydroxylase activity catalyzing the post-translational formation of 3-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens, especially types IV and V. May be involved in the secretory pathway of cells. Has growth suppressive activity in fibroblasts.
Subcellular locations: Endoplasmic reticulum
Subcellular locations: Secreted, Extracellular space, Extracellular matrix
Secreted into the extracellular matrix as a chondroitin sulfate proteoglycan (CSPG).