Microtubule-associated protein that exhibits cell cycle-dependent localization and can inhibit cell proliferation and migration.
Subcellular locations: Cell membrane, Cytoplasm, Cytoskeleton, Nucleus
Observed in the nucleus and at the perinuclear region during interphase, but localizes at the mitotic spindle and midbody at metaphase. A significant fraction of MARVELD1 translocates to the plasma membrane during anaphase or upon microtubule depolymerization (By similarity).
Widely expressed in normal tissues. Down-regulated in multiple primary tumors.