Plays a role in constitutive metalloproteinase (MMP) secretion from the trans Golgi network . May have important functions during vesicle biogenesis at certain cargo subdomains, which could be predominantly utilized by secreted MMPs, such as MMP7 and MMP2 . Also involved in autophagy by regulating the starvation-dependent trafficking of ATG9A vesicles which deliver the phosphatidylinositol 4-kinase beta (PI4KB) to the autophagosome initiation site (, ). Involved in phagophore growth during mitophagy by regulating ATG9A trafficking to mitochondria . In addition, plays a role in NF-kappa-B inhibition by interacting with IKBKB and IKBKG .
Subcellular locations: Golgi apparatus, Golgi apparatus, Trans-Golgi network membrane