Acts as a suppressor of ciliogenesis, specifically, the initiation of ciliogenesis.
Subcellular locations: Cytoplasm, Cytoskeleton, Microtubule organizing center, Centrosome, Cytoplasm, Cytoskeleton, Microtubule organizing center, Centrosome, Centriole, Cytoplasm, Cytoskeleton, Microtubule organizing center, Centrosome, Centriolar satellite, Cytoplasm, Cytoskeleton, Cilium basal body
Localizes to centrioles in proliferative cells and basal bodies in ciliated cells . Disappears during ciliogenesis but reappears, albeit at a lower levels once ciliogenesis has completed .
Subcellular locations: Cytoplasm, Cytoskeleton, Microtubule organizing center, Centrosome, Centriolar satellite
Not present in the centrioles in cycling cells. Disappears during ciliogenesis.
Subcellular locations: Cytoplasm, Cytoskeleton, Microtubule organizing center, Centrosome, Centriolar satellite, Cytoplasm, Cytoskeleton, Microtubule organizing center, Centrosome, Centriole
Disappears during ciliogenesis but reappears, albeit at a lower levels once ciliogenesis has completed.
Mainly expressed in trachea and testis. Not detected in bone marrow, bladder, leukocytes. Only weakly detected in tongue, stomach, brain and ovaries.