Putative function in synaptic vesicle exocytosis by binding to Munc18-1, an essential component of the synaptic vesicle exocytotic machinery. May modulate processing of the amyloid-beta precursor protein (APP) and hence formation of APP-beta. Component of the LIN-10-LIN-2-LIN-7 complex, which associates with the motor protein KIF17 to transport vesicles containing N-methyl-D-aspartate (NMDA) receptor subunit NR2B along microtubules (By similarity).
Subcellular locations: Cytoplasm, Cytoplasm, Perinuclear region, Nucleus
Only about 5% of the protein is located in the nucleus.
Subcellular locations: Golgi apparatus
Brain and spinal cord. Isoform 2 is expressed in testis and brain, but not detected in lung, liver or spleen.