Binds actin monomers (G actin) and plays a role in multiple processes including the regulation of actin cytoskeleton dynamics, actin stress fibers formation, cell motility and survival, formation of tubules by endothelial cells, and regulation of PPP1CA activity (, ). Involved in the regulation of cortical neuron migration and dendrite arborization (By similarity).
Subcellular locations: Cytoplasm, Synapse, Nucleus
Enriched at synapses (By similarity). Cytoplasmic in resting cells, and is imported into the nucleus upon serum stimulation. Interaction with actin prevents nuclear import (By similarity).
Detected in umbilical vein endothelial cells.