Acts as an important adapter that promotes epithelial cell polarity and tight junction formation via its interaction with DLG1. Involved in the assembly of protein complexes at sites of cell-cell contact.
Subcellular locations: Membrane, Lateral cell membrane, Cell junction, Tight junction, Cell junction, Adherens junction, Cytoplasm, Cell cortex, Cytoplasm
In epidermal cells, detected primarily at the lateral cell membrane.