Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 2 complex (dynein-2 complex), a motor protein complex that drives the movement of cargos along microtubules within cilia and flagella in concert with the intraflagellar transport (IFT) system, facilitating the assembly of these organelles . Involved in the regulation of ciliary length (, ).
Subcellular locations: Golgi apparatus, Cytoplasm, Cell projection, Cilium, Cytoplasm, Cytoskeleton, Cilium basal body, Cytoplasm, Cytoskeleton, Cilium axoneme, Cytoplasm, Cytoskeleton, Microtubule organizing center, Centrosome
Localizes to the apical cytoplasm.
Expressed in bone, brain, kidney, and cartilage (, ). Lower expression in heart, liver, lung, placenta and thymus .