May confer resistance to the antitumor agent cisplatin. Binds to DNA and RNA (By similarity).
Subcellular locations: Nucleus, Cytoplasm, Nucleus, Nucleolus, Nucleus, Cajal body, Nucleus, PML body
After treatment with proteasomal inhibitors and mild heat-shock stress is relocalized to the nucleolus as dot-like or irregular subnuclear structures. Colocalized with nuclear promyelocytic leukemia (PML) and Cajal bodies (CB); this association with nuclear bodies is enhanced in response to proteotoxic stress. Relocalized in nucleolar caps during transcriptional arrest (By similarity).