Regulates Wnt proteins sorting and secretion in a feedback regulatory mechanism. This reciprocal interaction plays a key role in the regulation of expression, subcellular location, binding and organelle-specific association of Wnt proteins . Plays also an important role in establishment of the anterior-posterior body axis formation during development (By similarity).
Subcellular locations: Golgi apparatus membrane, Cytoplasmic vesicle membrane, Cell membrane, Endoplasmic reticulum membrane, Golgi apparatus membrane, Early endosome membrane
Co-localizes with the adaptin AP2A2 at distinct punctae.