Actin-associated protein that may play a role in modulating actin-based shape and motility of dendritic spines and renal podocyte foot processes. Seems to be essential for the formation of spine apparatuses in spines of telencephalic neurons, which is involved in synaptic plasticity (By similarity).
Subcellular locations: Cytoplasm, Cytoskeleton, Cell junction, Tight junction, Perikaryon, Cell projection, Dendritic spine, Postsynaptic density, Synapse, Cytoplasm, Cytosol
Localized at the tight junction of cells. In brain, localized to the postsynaptic densities and in the perikarya. Associated with dendritic spines of a subset of synapses.
Expressed in cerebral cortex.