Cell adhesion glycoprotein which is widely distributed in basement membranes. Binds to collagens I and IV, to perlecan and to laminin 1. Does not bind fibulins. It probably has a role in cell-extracellular matrix interactions.
Subcellular locations: Secreted, Extracellular space, Extracellular matrix, Basement membrane
Detected in placenta (at protein level) . Heart and bone. Less in pancreas, kidney and skeletal muscle.