May regulate B-cell receptor (BCR)-induced immature and primary B-cell apoptosis. Plays a role as negative regulator of the canonical NF-kappa-B-activating branch. Controls spontaneous apoptosis through the regulation of BCL2L1 abundance.
Subcellular locations: Membrane raft
In a mouse immature B-cell line WEHI-231.
Found in lymphocytes; preferentially expressed in CD8+ cells.