Acts as a co-chaperone for HSP90 and is required for proper folding of the myosin motor domain. Plays a role in sarcomere formation during muscle cell development. Is necessary for normal early lens development.
Subcellular locations: Cytoplasm, Myofibril, Sarcomere, Z line, Cytoplasm, Myofibril, Sarcomere, A band, Cytoplasm, Perinuclear region, Cytoplasm, Cytosol
Expressed at the Z line and in the perinuclear region of myofibrils. Translocates to the A band in response to stress conditions and fibril damage.
Expressed in eye lens tissues. Expressed in muscle (at protein level) .