Calcium, potassium:sodium antiporter that transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+) (, ). Controls the rapid response termination and proper regulation of adaptation in olfactory sensory neurons (OSNs) which subsequently influences how odor information is encoded and perceived (By similarity). May play a role in calcium transport during amelogenesis (, ).
Subcellular locations: Cell membrane, Cytoplasm
Expressed abundantly in all regions of the brain, aorta, lung and thymus . Expressed at lower levels in the stomach and intestine .