Calcium-binding protein that may play a role in the adhesion of neutrophils to fibronectin. May play a role in the formation of focal adhesions.
Subcellular locations: Cytoplasm, Cytoplasmic granule membrane
Primarily cytosolic in the absence of calcium or magnesium ions. Relocates to granules and other membranes in response to elevated calcium and magnesium levels.
Detected in neutrophils and macrophages (at protein level). Highly expressed in bone marrow.