Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine.
Does not bind thyroid hormone and functions as a weak dominant negative inhibitor of thyroid hormone action.
Subcellular locations: Nucleus
Subcellular locations: Cytoplasm, Nucleus
When overexpressed found in the cytoplasm where it colocalizes with TACC1.