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The malonate or propanedioate ion is CH2 -LRB- COO -RRB- 22 − -LRB- malonic acid minus two hydrogen ions -RRB- .. ion. ion. malonic acid. malonic acid. Malonate compounds include salts and esters of malonic acid , such as. malonic acid. malonic acid. compounds. chemical compound. diethyl malonate , -LRB- C2H5 -RRB- 2 -LRB- C3H2O4 -RRB- ,. diethyl malonate. diethyl malonate. dimethyl malonate , -LRB- CH3 -RRB- 2 -LRB- C3H2O4 -RRB- ,. dimethyl malonate. dimethyl malonate. disodium malonate , Na2 -LRB- C3H2O4 -RRB- .. disodium malonate. disodium malonate. Malonate is a competitive inhibitor of the enzyme succinate dehydrogenase  : malonate binds to the active site of the enzyme without reacting , and so competes with succinate , the usual substrate of the enzyme .. competitive inhibitor. Competitive inhibition. enzyme. enzyme. succinate dehydrogenase. succinate dehydrogenase. active site. active site. succinate. Succinic acid. The observation that malonate is a competitive inhibitor of succinate dehydrogenase was used to deduce the structure of the active site in that enzyme.The chemical malonate decreases cellular respiration .. competitive inhibitor. Competitive inhibition. enzyme. enzyme. succinate dehydrogenase. succinate dehydrogenase. active site. active site. succinate. Succinic acid. It resembles the substrate succinate , without a - CH2-CH2 group required for dehydrogenation .. succinate. Succinic acid