VH1 was the channel where Celebrity Rehab with Dr. Drew aired.
A single-nucleotide polymorphism , often abbreviated to SNP -LRB- -LSB- ˈsnɪp -RSB- plural -LSB- ˈsnɪps -RSB- -RRB- , is a variation in a single nucleotide that occurs at a specific position in the genome , where each variation is present to some appreciable degree within a population -LRB- e.g. > 1 % -RRB- .. nucleotide. nucleotide. genome. genome. For example , at a specific base position in the human genome , the base C may appear in most individuals , but in a minority of individuals , the position is occupied by base A .. genome. genome. There is a SNP at this specific base position , and the two possible nucleotide variations -- C or A -- are said to be alleles for this base position .. nucleotide. nucleotide. SNPs underlie differences in our susceptibility to disease ; a wide range of human diseases , e.g. sickle-cell anemia , β-thalassemia and cystic fibrosis result from SNPs .. human diseases. human diseases. sickle-cell anemia. sickle-cell anemia. β-thalassemia. β-thalassemia. cystic fibrosis. cystic fibrosis. The severity of illness and the way our body responds to treatments are also manifestations of genetic variations .. For example , a single base mutation in the APOE -LRB- apolipoprotein E -RRB- gene is associated with a higher risk for Alzheimer 's disease .. apolipoprotein E. apolipoprotein E. A single-nucleotide variant -LRB- SNV -RRB- is a variation in a single nucleotide without any limitations of frequency and may arise in somatic cells .. nucleotide. nucleotide. somatic. Somatic mutation. A somatic single nucleotide variation -LRB- e.g. , caused by cancer -RRB- may also be called a single-nucleotide alteration .. nucleotide. nucleotide. somatic. Somatic mutation