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Multiple cutaneous leiomyomas , also known as Pilar leiomyomas , arise from the arrectores pilorum muscles , and are made up of a poorly circumscribed proliferation of haphazardly arranged smooth muscle fibers located in the dermis that appear to infiltrate the surrounding tissue and may extend into the subcutis .. arrectores pilorum. Arrector pili muscle. smooth muscle. smooth muscle. dermis. dermis. Sometimes associated with uterine leiomyomas -LRB- a combination known as multiple cutaneous and uterine leiomyomatosis , MCUL -RRB- , these lesions may also be a manifestation of the hereditary leiomyomatosis and renal cell cancer syndrome .. uterine leiomyomas. Uterine fibroid. multiple cutaneous and uterine leiomyomatosis. multiple cutaneous and uterine leiomyomatosis. hereditary leiomyomatosis and renal cell cancer. hereditary leiomyomatosis and renal cell cancer