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The Major Transitions in Evolution is a book written by John Maynard Smith and Eors Szathmary -LRB- Oxford University Press , 1995 -RRB- .. John Maynard Smith. John Maynard Smith. Eors Szathmary. Eors Szathmary. Oxford University Press. Oxford University Press. Evolution. Evolution ( journal ). This was a seminal publication that continues to contribute to ongoing issues in evolutionary biology .. At the time of its publication , Egbert Giles Leigh , Jr reviewing for Evolution commented that it `` may be the most important book on evolution since -LSB- R.A. -RSB- Fisher 's -LRB- 1930 -RRB- The Genetical Theory of Natural Selection '' .. Evolution. Evolution ( journal ). The Genetical Theory of Natural Selection. The Genetical Theory of Natural Selection. Maynard Smith and Szathmary authored a review article in Nature. Nature. Nature ( journal ). Maynard Smith and Szathmary identified several properties common to the transitions  :. Smaller entities have often come about together to form larger entities .. e.g. Chromosomes , eukaryotes , sex multicellular colonies .. Smaller entities often become differentiated as part of a larger entity .. e.g. DNA & protein , organelles , anisogamy , tissues , castes. DNA. DNA. protein. protein. anisogamy. anisogamy. The smaller entities are often unable to replicate in the absence of the larger entity .. e.g. DNA , chromosomes , Organelles , tissues , castes. DNA. DNA. The smaller entities can sometimes disrupt the development of the larger entity , e.g. Meiotic drive -LRB- selfish non-Mendelian genes -RRB- , parthenogenesis , cancers , coup d'etat. Meiotic drive. Meiotic drive. parthenogenesis. parthenogenesis. New ways of transmitting information have arisen.e.g .. DNA-protein , cell heredity , epigenesis , universal grammar .. DNA. DNA. protein. protein. epigenesis. epigenesis ( biology ). universal grammar. universal grammar. As stated by the authors , this book was aimed at professional biologists and assumes considerable prior knowledge .. They have also published a presentation of their ideas for a general readership under the title The Origins of Life -- From the Birth of Life to the Origins of Language .