Eddie Guerrero experienced drug addiction.
Substance abuse , also known as drug abuse , is a patterned use of a drug in which the user consumes the substance in amounts or with methods which are harmful to themselves or others , and is a form of substance-related disorder .. substance-related disorder. substance-related disorder. Widely differing definitions of drug abuse are used in public health , medical and criminal justice contexts .. In some cases criminal or anti-social behavior occurs when the person is under the influence of a drug , and long term personality changes in individuals may occur as well .. anti-social behavior. anti-social behavior. In addition to possible physical , social , and psychological harm , use of some drugs may also lead to criminal penalties , although these vary widely depending on the local jurisdiction .. Drugs most often associated with this term include  : alcohol , cannabis , barbiturates , benzodiazepines , cocaine , methaqualone , opioids and some substituted amphetamines .. alcohol. Ethanol. cannabis. cannabis. cocaine. cocaine. methaqualone. methaqualone. opioids. opioids. The exact cause of substance abuse is not clear , with theories including one of two  : either a genetic disposition which is learned from others , or a habit which if addiction develops , it manifests itself as a chronic debilitating disease .. In 2010 about 5 % of people -LRB- 230 million -RRB- used an illicit substance .. Of these 27 million have high-risk drug use otherwise known as recurrent drug use causing harm to their health , psychological problems , or social problems or puts them at risk of those dangers .. In 2015 substance use disorders resulted in 307,400 deaths , up from 165,000 deaths in 1990 .. Of these , the highest numbers are from alcohol use disorders at 137,500 , opioid use disorders at 122,100 deaths , amphetamine use disorders at 12,200 deaths , and cocaine use disorders at 11,100 .. alcohol. Ethanol. cocaine. cocaine. alcohol use disorders. alcohol use disorders