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Taxanes are a class of diterpenes .. They were originally identified from plants of the genus Taxus -LRB- yews -RRB- , and feature a taxadiene core .. Taxus. Taxus. taxadiene. taxadiene. Paclitaxel -LRB- Taxol -RRB- and docetaxel -LRB- Taxotere -RRB- are widely used as chemotherapy agents .. Paclitaxel. Paclitaxel. docetaxel. docetaxel. chemotherapy. chemotherapy. Cabazitaxel was FDA approved to treat hormone-refractory prostate cancer .. Cabazitaxel. Cabazitaxel. prostate cancer. prostate cancer. Taxanes present difficulties in formulation as medicines because they are poorly soluble in water .. formulation. Pharmaceutical formulation