Shadowhunters premiered in the 21st century.
The 21st century is the current century of the Anno Domini era , in accordance with the Gregorian calendar .. century. century. Anno Domini. Anno Domini. Gregorian calendar. Gregorian calendar. It began on January 1 , 2001 and will end on December 31 , 2100 .. It is the first century of the 3rd millennium .. century. century. 3rd millennium. 3rd millennium. It is distinct from the time span known as the 2000s , which began on January 1 , 2000 and will end on December 31 , 2099 .