History of Earth has sandstone part of it.
In enzymology , an estradiol 17alpha-dehydrogenase is an enzyme that catalyzes the chemical reaction. enzymology. enzymology. enzyme. enzyme. catalyzes. catalysis. chemical reaction. chemical reaction. estradiol-17alpha + NAD -LRB- P -RRB- + estrone + NAD -LRB- P -RRB- H + H +. estradiol-17alpha. estradiol-17alpha. estrone. estrone. The three substrates of this enzyme are estradiol-17alpha , NAD + , and NADP + , whereas its four products are estrone , NADH , NADPH , and H + .. enzyme. enzyme. substrates. substrate ( biochemistry ). estradiol-17alpha. estradiol-17alpha. products. product ( chemistry ). estrone. estrone. NADH. nicotinamide adenine dinucleotide. NADPH. nicotinamide adenine dinucleotide phosphate. This enzyme belongs to the family of oxidoreductases , specifically those acting on the CH-OH group of donor with NAD + or NADP + as acceptor .. enzyme. enzyme. The systematic name of this enzyme class is 17alpha-hydroxysteroid  : NAD -LRB- P -RRB- + 17-oxidoreductase .. enzyme. enzyme. oxidoreductase. oxidoreductase. systematic name. List of enzymes. Other names in common use include 17alpha-estradiol dehydrogenase , 17alpha-hydroxy steroid dehydrogenase , 17alpha-hydroxy steroid oxidoreductase , 17alpha-hydroxysteroid oxidoreductase , and estradiol 17alpha-oxidoreductase .. oxidoreductase. oxidoreductase. This enzyme participates in androgen and estrogen metabolism .. enzyme. enzyme. androgen. androgen. estrogen. estrogen