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Ezetimibe / atorvastatin -LRB- brand name Liptruzet -RRB- is a cholesterol lowering combination drug .. combination drug. combination drug. In the United States , it was approved in May 2013 by the Food and Drug Administration for the treatment of elevated low-density lipoprotein -LRB- LDL -RRB- in patients with primary or mixed hyperlipidemia as adjunctive therapy to diet .. Food and Drug Administration. Food and Drug Administration. low-density lipoprotein. low-density lipoprotein. hyperlipidemia. hyperlipidemia. adjunctive therapy. adjunctive therapy. Liptruzet has also been approved to reduce elevated total cholesterol and elevated LDL in patients diagnosed with homozygous familial hypercholesterolemia as an adjunctive treatment to other hyperlipidemia treatments .. hyperlipidemia. hyperlipidemia. Some cardiologists opposed the approval , because the combination reduced LDL cholesterol in a clinical trial , but it did not reduce heart disease .. A clinical trial studying the endpoints of heart attacks , strokes and heart-related deaths is scheduled to conclude in 2014 .