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A-84543 is a drug developed by Abbott , which acts as an agonist at neural nicotinic acetylcholine receptors with high selectivity for the α4β2 subtype .. Abbott. Abbott Laboratories. α4β2. Alpha-4 beta-2 nicotinic receptor. It is widely used in scientific research into the structure and function of this receptor subtype and has been the lead compound for the development of a large family of related derivatives .. lead compound. lead compound