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Inotek Pharmaceuticals is a clinical-stage biopharmaceutical company based in Lexington , Massachusetts focused on the discovery , development and commercialization of novel therapies to treat glaucoma and other serious diseases of the eye .. glaucoma. glaucoma. The Company 's lead product candidate , trabodenoson -LRB- formerly known as INO-8875 -RRB- , is being evaluated for the treatment of elevated intraocular pressure associated with primary open-angle glaucoma -LRB- POAG -RRB- and ocular hypertension -LRB- OHT -RRB- .. glaucoma. glaucoma. ocular hypertension. ocular hypertension. Trabodenoson has completed Phase 1 , 2 , and 3 clinical trials in subjects with OHT and POAG .. Inotek is developing trabodenoson as a monotherapy delivered via eye drop , as well as a fixed-dose combination -LRB- FDC -RRB- with latanoprost , one of the leading current treatments for OHT and POAG .. latanoprost. latanoprost