Martin Van Buren refused to be Secretary of State.
Bluffton is a Lowcountry town in Beaufort County , South Carolina , United States .. Beaufort County. Beaufort County, South Carolina. South Carolina. South Carolina. United States. United States. Beaufort. Beaufort County, South Carolina. Lowcountry. Lowcountry. town. town. It is primarily located around U.S. Route 278 , between Hilton Head Island and Interstate 95 .. U.S. Route 278. U.S. Route 278. Hilton Head Island. Hilton Head Island. Interstate 95. Interstate 95. The town 's original one square mile area , now known as Old Town , is situated on a bluff along the May River .. Town. Town. town. town. The population was counted by the 2010 census at 12,893 .. 2010 United States Census. 2010 census. 2010 United States Census. Bluffton is the fastest growing municipality in South Carolina with a population over 2,500 , growing 882.7 % between the 2000 and 2010 census .. South Carolina. South Carolina. 2010 United States Census. 2010 census. 2010 United States Census. Bluffton is the fifth largest municipality in South Carolina by land area .. South Carolina. South Carolina. The town is a primary city within the Hilton Head Island-Bluffton-Beaufort , SC Metropolitan Statistical Area .. Beaufort. Beaufort County, South Carolina. town. town. Hilton Head Island. Hilton Head Island. Bluffton is known for its eclectic Old Town district and natural views of the May River .. Town. Town. It has been called `` the last true coastal village of the South . ''. Following the Tariff of 1842 , Bluffton became a hotbed of separatist sentiment .. Tariff of 1842. Tariff of 1842. In 1844 the Bluffton Movement , a protest against federal taxes , gave birth to the secession movement and led South Carolina to be the first state to leave the Union .. South Carolina. South Carolina. Bluffton Movement. Bluffton Movement. secession. secession. In the antebellum period Bluffton became a popular location for wealthy merchants and plantation owners .. During the Civil War two-thirds of the town was destroyed by fire during the Union 's Bluffton Expedition on June 4 , 1863 .. town. town