Cardiovascular diseases (CVDs) are the group of diseases that occur in blood vessels and heart, the most common cause of death worldwide. The treatment of this cardiovascular disease is using as an enzyme treatment such as streptokinase, urokinase, tPA, etc. This type of enzymatic drugs has some side effects. To overcome this problem, novel therapeutic enzymes are isolated from different sources. This review focused on novel microorganisms fibrinolytic enzymes produced from different sources and different types of thrombosis. This review is also focused on fibrinolytic enzymes or thrombolytic agents act on novel coronavirus. © 2021, The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.
Present and Future Prospectives of Microbial Fibrinolytic Enzyme Production and Its Applications