Objective: To analyze the clinical data and risk factors of long-term coronavirus positive nucleic acids in patients with coronavirus disease in 2019 (COVID-19), and provide clinical guidance for the management of such patients Methods: The clinical data of 989 patients with COVID-19 were retrospectively analyzed, and patients were divided into three groups according to the duration of nucleic acid positivity Patients with positive nucleic acids for coronavirus for a duration of 1-5 days were regarded as the short-term group, patients who were positive for coronavirus nucleic acids for 6-22 days were set as the mid-term group, and those who were positive for corona-virus nucleic acids for more than 23 days were set as the long-term group We analyzed their clinical data including clinical features, laboratory tests, imaging features and treatment outcomes, and finally explored the risk factors for long-term nucleic acid positivity in COVID-19 patients Results: There were significant differences among the three groups in terms of clinical features (such as age, diabetes and respiratory diseases), laboratory test results (such as neutrophil count, lymphocyte count and creatinine levels) and imaging features (such as reticular nodule shadow and involved lung lobes) Age, diabetes mellitus, reticular nodule shadow, involvement of lung lobes, abnormal cre-atinine level and lymphocyte counts were risk factors for long-term positive coronavirus nucleic acids in COVID-19 patients Conclusion: age, diabetes, reticular nodule shadow, involvement of lung lobes, abnormal creatinine levels and lymphocyte counts can help doctors identify COVID-19 patients with higher risk factors
Analysis of clinical data and risk factors of long-term coronavirus positive nucleic acids in novel patients