The rapid spread of coronavirus disease COVID-19 in many countries to causes citizens of daily inconvenience, with even life-threat. Dexamethasone is a corticosteroid applied in clinical medicine since 1957 majored in immune therapy fields. Herein, we present the aspects of Dexamethasone from molecular mechanisms as genomic and non-genomic pathways by cellular signal regulations to clinical application in various treatment of disease status. During COVID-19 pandemic, new observation about dexamethasone in patients required oxygen or ventilation therapy demonstrates the life efficacy by Dexamethasone intake during the risk of death.
Pandemic Aspect of Dexamethasone: Molecular Mechanisms and Clinic Application