Development of vaccines to fight COVID19has been a remarkable medical achievement. However, this global immunization effort has been complicated by arare vaccine-related outcome characterized by thrombocytopenia and thrombosisin association with platelet-activating anti-platelet factor 4 antibodies.In this Spotlight article, we will discuss the recently described complication of vaccine-induced immune thrombotic thrombocytopenia (VITT)occurring in response to certain COVID19 vaccines. Although information about this clinical condition is rapidly evolving, we will summarize our current understanding of VITT.
Vaccine-Induced Immune Thrombotic Thrombocytopenia (VITT): What We Know and Don't Know