O8 Figure 1Flow chart showing TTG-IgA and histological correlation for children with suspected CD CD, celiac disease;GFD, gluten free diet;MO-HG, Marsh Oberhuber histological grading;TTG-IgA, IgA-based anti-tissue transglutaminase antibody;UGIE, upper gastrointestinal endoscopy;ULN, upper limit of normal[Figure omitted See PDF]ConclusionThis study showed that 99 5% of children with TGA-IgA ≥5xULN had clear histological confirmation of CD with p&lt;0 00001 compared to TGA-IgA&lt;5xULN For the same advantages of the current NBP and considering the challenges posed by the COVID-19 pandemic, changing the guidance to TGA-IgA ≥5xULN appears to be safe and secure for diagnosis of CD in children
O8 Is anti-tissue transglutaminase antibody titre greater than five times upper limit of normal suitable for no-biopsy pathway diagnosis of coeliac disease?