There is a deep need for mortality predictors that allow clinicians to quickly triage patients with severe coronavirus disease 2019 (Covid-19) into intensive care units at the time of hospital admission Thus, we examined the efficacy of the lymphocyte-to-neutrophil ratio (LNR) and neutrophil-to-monocyte ratio (NMR) as predictors of in-hospital death at admission in patients with severe Covid-19 A total of 54 Mexican adult patients with Covid-19 that met hospitalization criteria were retrospectively enrolled, followed-up daily until hospital discharge or death, and then assigned to survival or non-survival groups Clinical, demographic, and laboratory parameters were recorded at admission A total of 20 patients with severe Covid-19 died, and 75% of them were men older than 62 90 +/- 14 18 years on average Type 2 diabetes, hypertension, and coronary heart disease were more prevalent in non-survivors As compared to survivors, LNR was significantly fourfold decreased while NMR was twofold increased LNR = 17 75 was a better independent risk factor for mortality with a sensitivity of 89 47% and a specificity of 80 00% This study demonstrates for the first time that NMR and LNR are accurate predictors of in-hospital mortality at admission in patients with severe Covid-19
The Neutrophil-to-Monocyte Ratio and Lymphocyte-to-Neutrophil Ratio at Admission Predict In-Hospital Mortality in Mexican Patients with Severe SARS-CoV-2 Infection (Covid-19)