Relying on traditional diagnostic approaches like quantitative polymerase chain reaction is not appropriate for both time and cost in sudden outbreaks and pandemics such as COVID-19 In such cases, diagnostic approaches through rapid sequencing of pathogenic DNA and RNA are important for accelerated clinical prognosis FNCas9 Editor-Linked Uniform Detection Assay (FELUDA) is one such diagnostic approach toward the pathogenic genome, developed by CSIR-IGIB FELUDA is a paper strip diagnostic test like pregnancy, based on clustered regularly interspaced short palindromic repeats/Cas technology of gene editing FELUDA showed 96% sensitivity and 98% specificity across all range of viral loads in clinical samples Due to its low cost, it can drastically reduce the Indian budget toward the rapid testing and COVID-19 diagnostic kits © 2021 Royal Society of Chemistry All rights reserved
FNCas9 editor-linked uniform detection assay: An innovative COVID-19 sleuth