Various nanoparticles have been developed for bio-applications. However, nanocomposites particles, (NCPs) with effective and ability to sensing cholesterol, are still needed. Herein, we present new cholesterol and pH-responsive NCPs as sensor particles to promote sensitivity. The traditional method of mixing and grinding was used to fabricate the oxides of magnesium and manganese MgO–MnO(2) NCPs with different mixing ratios. Structural properties, detection of cholesterol, and pH sensitivity were examined. Results propped the high efficiency of MgO–MnO(2) NCPs compared with individual oxides (MgO and MnO(2)), low response time, while the analytical results confirmed the homogeneous structure of MgO–MnO(2) NCPs. Particle size distribution results for NCPs were within 16.4 to 100 nm, which makes it promising in medical and bio-applications.
Preparation of MgO–MnO(2) nanocomposite particles for cholesterol sensors