Lateral flow assay (LFA) has long been used as a biomarker detection technique It has advantages such as low cost, rapid readout, portability, and ease of use However, its qualitative readout process and lack of sensitivity are limiting factors We report a photon-counting approach to accurately quantify LFAs while enhancing sensitivity In particular, we demonstrate that the density of SARS-CoV-2 antibodies can be quantified and measured with an enhanced sensitivity using this simple laser optical analysis
Enhancing sensitivity of lateral flow assay with application to SARS-CoV-2