Concern has arisen that the purported similarity between syncytin-1 and the SARS-CoV-2 spike protein may induce immune cross reactivity resulting in female sterility. We used frozen embryo transfer as a model to compare implantation rates between SARS-CoV-2 vaccine seropositive, infection seropositive and seronegative women. We found no difference in serum hCG documented implantation rates or sustained implantation rates between the three groups. The concern regarding Covid vaccines or illness causing female sterility are unfounded.
SARS-CoV-2 spike protein seropositivity from vaccination or infection does not cause sterility