A unique feature of COVID-19 interstitial pneumonia is an abrupt progression to respiratory failure. Our calculation shows that this abrupt deteriorate may be caused by a sudden shift in the spread of virus-laden bioaerosols through the airways to many different regions of the lungs from the initial site of infection. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s10439-020-02676-w) contains supplementary material, which is available to authorized users.
Abrupt Deterioration of COVID-19 Patients and Spreading of SARS COV-2 Virions in the Lungs