• Two cases of Serotonin syndrome (SS) in COVID-19 patients are presented. • Lopinavir/ritonavir (LPV/r) have been widely used during the COVID-19 pandemic. • LPV/r with duloxetine and lithium triggered SS in patient 1. • LPV/r with risperidone, and probably also morphine, triggered SS in patient 2. • A Video of patient 2 shows myoclonus and ocular clonus in the context of SS.
Serotonin syndrome in two COVID-19 patients treated with lopinavir/ritonavir