Background Hypertension, as the most common comorbidity for patients with coronavirus disease 19 (COVID-19), has resulted in cases with more severe symptoms and higher mortality The risk factors associated with COVID-19 in patients with hypertension are unknown Methods All the available and confirmed patients with COVID-19 from February 3 to March 10, 2020, were enrolled from Huoshenshan Hospital, Wuhan, China The demographic characteristics, clinical manifestations, laboratory data, radiological assessments, and treatments on admission were extracted and compared Univariate and multivariate logistic regression methods were used to explore risk factors associated with COVID-19 in patients with hypertension and the severity of the cohort Results A total of 430 available patients with COVID-19 were enrolled in the study, including 151 eligible patients with COVID-19 and hypertension After PSM analysis, 141 patients without hypertension and 141 cases with hypertension were well matched Compared with cases without hypertension, patients with hypertension were more severe (28 4% vs 12 1%, p = 0 001) In multivariate analysis, we found that neutrophil count (OR: 1 471;p = 0 001), coronary heart disease (OR: 5 281;p = 0 011), and the level of K+ (OR: 0 273;p &lt; 0 001) were associated with patients with hypertension In addition, the percentage of pulmonary infection volume was larger in cases with hypertension (4 55 vs 5 8, p = 0 017) and was a high risk factor for severe COVID-19 in patients with hypertension (OR: 1 084;p &lt; 0 001) Conclusion On admission, coronary heart disease, neutrophil count, and the level of K+ were associated with COVID-19 patients with hypertension The percentage of the pulmonary infection volume was significantly larger in COVID-19 patients with hypertension and was a risk factor for COVID-19 severity of the cohort [ABSTRACT FROM AUTHOR] Copyright of Canadian Journal of Infectious Diseases & Medical Microbiology is the property of Hindawi Limited and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission However, users may print, download, or email articles for individual use This abstract may be abridged No warranty is given about the accuracy of the copy Users should refer to the original published version of the material for the full abstract (Copyright applies to all Abstracts )
Risk Factors for COVID-19 in Patients with Hypertension