Pulmonary alveolar proteinosis (PAP) is a rare, diffuse pulmonary disease due to abnormal surfactant homeostasis We present the case of a 69-year-old woman who was admitted to the hospital for progressive dyspnea with marked limitation in activity, and non-productive cough, of three months of evolution Type I respiratory failure was confirmed Chest tomography findings were interlobular and intralobular septal thickening, ground glass opacities and bilateral consolidation Histological diagnosis was made and whole-lung lavage was performed with clinical improvement We highlight the need to keep in mind differential diagnoses of respiratory failure and pulmonary infiltrates during COVID-19 pandemic, even rare entities such as PAP
[Pulmonary alveolar proteinosis]