Objective: The objective of this study was to compare platelet mass index, platelets count/mean platelet volume and other hemogram parameters between COVID-19 patients and a control group and to determine the parameters that are significant in discrimination between COVID-19 and healthy control patients without COVID 19 Methods: Data of a total of 80 patients who presented to the emergency department of our hospital with the symptoms suggesting COVID-19 with a polymerase chain reaction (PCR) positive result and 80 healthy controls with a PCR (-) test results were retrospectively analyzed Patients' laboratory parameters including white blood cells (WBC), neutrophils count, lymphocytes count, monocytes count, neutrophils to lymphocytes ratio ( NLR), lymphocytes to monocytes ratio (LMR), platelets (PLT), platelets to lymphocytes ratio (PLR), mean platelet volume (MPV), red blood cell distribution width (RDW), platelet mass index (PMI), red blood cell distribution width/mean platelet volume (RDW/MPV) and platelet count/ mean platelet volume (PLT/MPV) ratios were analyzed At the same time a receiver operating characteristic (ROC) analysis was performed for determining laboratory indicators in distinguishing control and COVID-19 positive cases from each other Results: In our stuy, WBC, lymphocytes, monocytes, neutrophils, LMR, platelets, PMI and PLT/MPV levels decreased, while PLR and MPV values increased in COVID-19 patients According to ROC analysis, among the parameters examined in terms of making discrimination between COVID-19 and contol groups, LMR, PLR, PMI and PLT/MPV parameters had significant areas under curve The best cut-off points of the parameter were found as &lt;2 91 for LMR, 117 95 for PLR, 2167 65 for PMI and &lt;25 13 for PLT/MPV Conclusions: Our study revealed decreased WBC, lymphocytes, monocytes, neutrophils, LMR, platelets, PMI and PLT/MPV levels and elevated PLR and MPV values in COVID-19 patients We believe that these parameters can be helpful in follow-up of the prognosis of COVID-19 patients and distinguishing these patients from healthy persons without COVID-19
Diagnostic Value of Platelet Mass Index, Plt/Mpv Ratio and Other Hemogram Parameters in Covid-19 Patients Who Presented to Emergency Department