A perplexing clinical aspect of COVID-19 is presentation of patients with pronounced hypoxemia without expected signs of respiratory distress or dyspnea, even when cyanotic Nonetheless, these patients frequently leapfrog clinical evolution stages and suffer acute respiratory distress syndrome (ARDS), with concomitant cardiorespiratory arrest and death [1] This phenomenon is referred to as silent or 'happy' hypoxemia
Silent or 'Happy' Hypoxemia: An Urgent Dilemma for COVID-19 Patient Care