BACKGROUND: The novel SARS-CoV-2, responsible for the most recent pandemic faced by humanity, has become a global crisis causing millions of deaths. The virus is transmitted by inhalation of infectious particles suspended in the air, direct deposition on mucous membranes and indirect contact via contaminated surfaces. Therefore, disinfection methods that can halt such transmission are important in this pandemic and in future viral infections. AIM: Highlight the efficacy of several disinfection methods against SARS-CoV-2, based on up-to-date evidence found in literature. METHODS: A research was conducted through two databases to assess the disinfection methods used against SARS-CoV-2. From a total of 1229 studies found, 60 were included. Quality assessment was evaluated by the OHAT risk of bias tool. FINDINGS: Disinfection methods on environmental surfaces were approached by 28 studies; 16 articles addressed disinfection methods used on biological surfaces; 4 articles presented disinfection methods for airborne coronavirus and 16 studies demonstrated methods used to recondition PPEs. CONCLUSIONS: Several household and hospital disinfection agents and UV-C irradiation were effective in inactivating SARS-CoV-2 on environmental surfaces. Formulations containing povidone-iodine can provide virucidal action on the skin and mucous membranes. In the case of hand hygiene, typical soap bars and alcohols can inactivate SARS-CoV-2. Air filtration systems incorporated with materials that possess catalytic properties, UV-C devices and heating systems can effectively reduce airborne viral particles. The decontamination of PPEs can be conducted safely by heat and ozone treatment.
Disinfection methods against SARS-CoV-2: a systematic review