Objectives: To assess the impact of lymphopenia on the COVID-19 disease outcome. Study Design: Retrospective study. Setting: ICU and Isolation Ward of Hayatabad Medical Complex, Peshawar. Period: July 2020 to Dec 2020. Material & Methods: Different parameters of CBC were performed using the five parts Sysmex differential hematology analyzer BS-1800. A total of 274 patients were included via non probability sampling. Relevant information's were recorded on a pre-designed performa prepared in accordance with the objectives of the study. Results: The absolute lymphocyte count was lower in patients who were admitted in ICU as compared to those in isolation ward (p-value 0.07). Likewise patients with severe lymphocytopenia (lymphocyte count less than 50x10*9/L) had a greater rate of mortality (p value 0.01). No significant difference in term of TLC and ANC was noted in survivor's vs non survivors groups in present study. Conclusion: Our study concludes that lymphopenia serves as a reliable and early prognostic factor in determining disease severity and mortality COVID-19. [ FROM AUTHOR] Copyright of Professional Medical Journal is the property of Professional Medical Journal and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full . (Copyright applies to all s.)
Lymphopenia is an indicator of severity of the disease and predicts mortality in COVID-19