A COVID-19 outbreak suddenly appeared in Wuhan, China, in December 2019, and then spread around the world quickly. So far, there have been a series of studies on SARS-COV-2 which has been confirmed as the cause of the outbreak. On account of the characteristic of spreading in droplet, SARS-COV-2 could be transmitted from person to person, causing the epidemic to become more and more severe all over the world. For SARS-COV-2, the spike S protein is essential for successfully infecting cells. In fact, most developmental strategies of vaccines are based on the structure of S proteins as well as host cell receptors. There are also vaccines based on the role of RNA molecules of SARS-COV-2 in host cells or the immune response of human body against the virus. This paper summarizes some research results of scholars on SARS-COV-2, aiming to provide people with a clear idea to understand SARS-COV-2, and hoping to make some contributions to the fight against the virus. © The Authors, published by EDP Sciences, 2021.
The scientific research progress of novel coronavirus - - SARS-COV-2