Coronavirus disease (COVID-19) is caused by severe acute respiratory syndrome coronavirus-2 (SARS-COV-2) signifies the causative agent of a potentially lethal disease that is of abundant world-wide public health concern. It was emerged in Wuhan, China and spread globally. On 30 January 2020, World Health Organization (WHO) officially professed the COVID-19 epidemic as a public health emergency of international concern. In accordance to the genomic analysis, Genomic analysis revealed that SARSCoV-2 is phylogenetically related to severe acute respiratory syndrome-like (SARS-like) bat viruses, therefore bats could be the possible primary reservoir. Despite of unknown intermediate source, the rapid human to human transfer has been widely assured. Extensive strategies have come forward to reduce person-to-person transmission of COVID-19 in order to control the current outbreak. Special attention and efforts should be taken into consideration to protect or reduce transmission in susceptible population including children, health care providers, and elderly people. There is no clinically approved antiviral drug or vaccine available till date against COVID-19. However, investigations have been carried out using broad-spectrum antiviral drugs against COVID-19 in clinical trials, that resulted in clinical recovery. In this review, we have discussed about the symptoms, structure, epidemiology, transmission, pathogenesis, diagnosis and potential treatment availability to control the spread of this fatal disease.
Review on COVID-19: a global pandemic disease