Artificial Sweeteners Found More Weight-Promoting Than SugarSayer Ji, Contributor The researchers set out to experimentally confirm the suggestion that the use of nonnutritive sweeteners can lead to weight gain, noting that evidence regarding their real effect on body weight and satiety is still inconclusive. In the study design, twenty-nine male rats received plain yogurt sweetened with 20% sucrose, 0.3% sodium saccharin or 0.4% aspartame, in addition to chow and water without restriction. After measuring their cumulative body weight gain, total caloric intake, caloric intake of chow and caloric intake of sweetened yogurt weekly for 12 weeks, they concluded greater weight gain was promoted by the use of saccharin or aspartame, compared with sucrose, and this weight gain was unrelated to caloric intake. We speculate that a decrease in energy expenditure or increase in fluid retention might be involved. Satiety, that is, the ability to satisfy the appetite, should be a function of how nourishing something is. Artificial sweeteners, which divorce sweetness from caloric content (i.e. nourishment), leave the cells without the monosaccharides primarily glucose they need and crave, and which is why the sensation of sweetness is hard-wired in our bodies to illicit a feeling of pleasure. Ultimately, nonnutritive synthetic sweeteners could be considered neuroendocrine disruptors, breaking, altering or amplifying the intimately connected feedback loops between pleasure and nourishment, deprivation and fat-storage, exertion and inactivity, some of which are as ancient as life itself. The challenge for millions of consumers around the world is clearly recognizing the dangers ofartificial sweeteners like aspartame, given it is safety approved in 90 nations. Despite reassurances from many world governments, manufacturers and marketers, the research itself does not lend unequivocal support to the view that they are entirely safe. For those interested in viewing the other side of the evidence, you will find peer-reviewed and published research on our site linking aspartame to over 40 adverse health effects, including fibromyalgia, brain cancer, kidney damage, urinary tract cancer, leukemia and many other serious conditions.[v] Saccharin has also been linked to urinary tract cancer, DNA damage, aging, atherosclerosis, and hyperinsulinism.[vi] For healthy alternatives to synthetic sweeteners and sugar, read: Sweet! Dieting Without the Deprivation. *GreenMedInfo.com cites and indexes research performed on animals. Please view our position on animal experimentation and cruelty on our dedication page. Resources [ii] Claudia Twum, Yudan Wei. The association between urinary concentrations of dichlorophenol pesticides and obesity in children. Rev Environ Health. 2011 ;26(3):215-9. PMID: 22206198 [iii] Monika Rnn, Lars Lind, Bert van Bavel, Samira Salihovic, Karl Michalsson, P Monica Lind.Circulating levels of persistent organic pollutants associate in divergent ways to fat mass measured by DXA in humans. Chemosphere. 2011 Jul 16. Epub 2011 Jul 16. PMID: 21767864 [iv] Duk-Hee Lee, Michael W Steffes, Andreas Sjdin, Richard S Jones, Larry L Needham, David R Jacobs. Low dose organochlorine pesticides and polychlorinated biphenyls predict obesity, dyslipidemia, and insulin resistance among people free of diabetes. PLoS One. 2011;6(1):e15977. Epub 2011 Jan 26. PMID: 21298090 [v] GreenMedInfo.com, Adverse Health Effects of Aspartame [vi] GreenMedInfo.com, Adverse Health Effects of Saccharin This article first appeared at GreenMedInfo. Please visit to access their vast database of articles and the latest information in natural health. linkwithin_text=Related Articles: 