Green Coffee Health Benefits: Real or Imagined?Sayer Ji, Contributor This is not to say that roasted coffee does not have its benefits too. In fact, research from the mid-80s found that roasting coffee produces unique cancer-suppressing compounds not found in green coffee.[iv] Also, technically, the vast majority of studies performed on coffees health benefits are on the roasted form, as this is what most people consume globally. There may also be unique mood-enhancing, even opiate-like properties in the roasted coffee bean associated with the fat-soluble compound known as cafestrol, which may not be found (or easily absorbed) in green coffee. But this benefit may also be a liability for those who may be prone to drinking too much, or feel they are prone to being addicted to habitual coffee consumption. But one thing that green coffee definitely has going for it is the fact that it is far higher in sheer antioxidant potential than roasted coffee, and most anything else we consume or drink on a daily basis. Some green coffee bean extracts score 2500 or higher on the ORAC scale, which stands for Oxygen Radical Absorbance Capacity an abstract measurement of the potential for a substance to reduce oxidative stress. Compare this to an equal weight of blueberries, which scores 10, or Oranges which score 3. This is not to say that blueberries and oranges do not have their own unique health benefits beyond what the ORAC score can reveal which they do! but that the green coffee bean is simply a highly concentrated source of antioxidant compounds. And considering how stress, chemical exposures, dietary deficiencies and/or incompatibilities, all lead to increasing oxidative stress in the body (which is a cause of premature aging, cellular damage, and even increased risk for cancers) increasing antioxidant levels in our diet can make a world of difference. So, what are the likely health benefits of green coffee? Despite the present Oz-generated craze to identify green coffee consumption with weight loss, the primary finding is that it has beneficial blood pressure modulating properties. Green Coffee Lowers Blood Pressure Back in 2005, a study published in the journal Hypertension Research found that male volunteers with mild hypertension given various doses of a water-soluble green coffee bean extract (GCE) saw significant reductions , in a dose-related manner, in both diastolic and systolic blood pressure.[vi] The subjects received either 46 mg, 93 mg, or 185 mg of GCE once a day for 28 days. Another study performed in 2006 found similar blood pressure lowering results using 140 mg/day green coffee bean extract of chlorogenic acid . [vii] Finally, a study performed in 2007 found that green coffee is superior to roasted coffee in reducing blood pressure, due to its lower levels of hydroxyhydroquinone, a by-product of the roasting process.[viii] The ordinary coffee group experienced almost no effect. Green Coffee Reduces Weight and Body Mass Index, and May Improve Type 2 Diabetes In the most widely publicized study on green coffee, Dr. Joe Vinson of the University of Scranton lead a randomized, double-blind and placebo-controlled crossover study which found that the consumption of green coffee bean extract reduced weight in overweight subjects.[ix] Subjects received either a high dose green coffee extract (1050 mg), a lower dose (700 mg) or a placebo for six-weeks, followed by a two-week washout period to reduce any influence of preceding treatment. Primary measurements were body weight, body mass index, and percent body fat. Blood pressure and heart rate were also measured. The results were a significant reduction in observed body weight: (-8.04 2.31 kg), body mass index (-2.92 0.85 kg/m(2)), and percent body fat (-4.44% 2.00%), as well as a small decrease in heart rate (-2.56 2.85 beats per minute). There we no significant changes to the diet over the course of the study, and impressively, body mass index for six subjects shifted from preobesity to the normal weight range. The study concluded: The results are consistent with human and animal studies and a meta-analysis of the efficacy of green coffee extract in weight loss. The results suggest that GCA may be an effective nutraceutical in reducing weight in preobese adults, and may be an inexpensive means of preventing obesity in overweight adults. Dr. Vinson believes that green coffees uniquely high concentration of chlorogenic acid relative to the roasted form may be responsible for some of its observed weight-loss promoting effects. Chlorogenic acid is known to increase the absorption of glucose, which offsets some of the insulin resistance and blood sugar elevations associated with type 2 diabetes. Indeed, there is a solid body of clinical literature linking chlorogenic acid to the well-known anti-diabetic properties of coffee. So, is green coffee a new magic bullet, or is it just another fad? We dont know. But, relative to some of the pharmaceutical interventions used today to treat overweight and obesity, diabetes and high blood pressure, the research thus far indicates green coffee may make for a promising natural alternative. Hypertension Resources [ii] L K Lam, V L Sparnins, L W Wattenberg. Isolation and identification of kahweol palmitate and cafestol palmitate as active constituents of green coffee beans that enhance glutathione S-transferase activity in the mouse. Cancer Res. 1982 Apr ;42(4):1193-8. PMID: 7059995 [iii] L W Wattenberg. Inhibition of neoplasia by minor dietary constituents. Cancer Res. 1983 May ;43(5 Suppl):2448s-2453s. PMID: 6403236 [iv] H Obana, S Nakamura, R Tanaka. Suppressive effects of coffee on the SOS responses induced by UV and chemical mutagens. Mutat Res. 1986 Oct ;175(2):47-50. PMID: 3093858 [v] Highbeam.com, The Muslin Agricultural Revolution, Jan. 2002 [vi] Kazuya Kozuma, Shigemi Tsuchiya, Jun Kohori, Tadashi Hase, Ichiro Tokimitsu.Antihypertensive effect of green coffee bean extract on mildly hypertensive subjects.Hypertens Res. 2005 Sep;28(9):711-8. PMID: 16419643 [vii] Takuya Watanabe, Yoichi Arai, Yuki Mitsui, Tatsuya Kusaura, Wataru Okawa, Yasushi Kajihara, Ikuo Saito. The blood pressure-lowering effect and safety of chlorogenic acid from green coffee bean extract in essential hypertension. Clin Exp Hypertens. 2006 Jul;28(5):439-49. PMID: 16820341 [viii] Tohru Yamaguchi, Akiro Chikama, Kenta Mori, Takuya Watanabe, Yasushi Shioya, Yoshihisa Katsuragi, Ichiro Tokimitsu. Hydroxyhydroquinone-free coffee: a double-blind, randomized controlled dose-response study of blood pressure. Nutr Metab Cardiovasc Dis. 2008 Jul;18(6):408-14. Epub 2007 Oct 22. PMID: 17951035 [ix] Joe A Vinson, Bryan R Burnham, Mysore V Nagendran. Randomized, double-blind, placebo-controlled, linear dose, crossover study to evaluate the efficacy and safety of a green coffee bean extract in overweight subjects. Diabetes Metab Syndr Obes. 2012 ;5:21-7. Epub 2012 Jan 18. PMID: 22291473 linkwithin_text=Related Articles: 