A novel and highly stereoselective synthesis of 2-substituted perhydrofuro[2,3-b]pyran derivatives.
An effective and facile method for the synthesis of 2-substituted perhydrofuro[2,3-b]pyran derivatives is described. The cyclization of 2-C-aldehydo-2-deoxy-D-thioglucoside in the presence of N-iodosuccinimide (NIS) is highly stereoselective. 2-Substituted cyclization products were obtained in good to excellent yields.
PubMed Abstracts
PubMed Abstracts