Sarcosine based indandione hGlyT1 inhibitors.
A series of sarcosine based indandione hGlyT1 inhibitors has been developed. Optimization of substitution around the indandione and sarcosine moieties has led to highly potent inhibitors at hGlyT1, which show selectivity over a number of other receptors.
PubMed Abstracts
PubMed Abstracts