Enzyme-regulated topology of a cyclic peptide brush polymer for tuning assembly.
Norbornenyl cyclic elastin-like peptides were polymerized via ring opening metathesis polymerization (ROMP) to generate thermally responsive brush polymers. The thermally-responsive nature of the materials could be attenuated by the addition of a proteolytic enzyme that causes the cyclic peptide side chains to be linearized.
PubMed Abstracts
PubMed Abstracts