[Intensified virulence of the causative agent in the process of the formation of a focus of cutaneous leishmaniasis].
A possible effect of a new epidemic nidus "age" on the virulence of Leishmania was studied. For a period of 9 years 16 strains were isolated from man affected with leishmaniosis. Infectivity of all strains was high (100% infection of animals). The incubative period of the disease in animals was the shorter the more years passed from the moment of the nidus formation. Strains isolated within the first 4-5 years caused leishmaniosis in 2-3 months and those isolated during subsequent years--in 1 to 3 weeks.
PubMed Abstracts
PubMed Abstracts