Dexamethasone iontophoresis for the treatment of nail psoriasis.
Severe nail psoriasis can impact significantly on quality of life and is difficult to treat. This is a retrospective study of all patients treated with dexamethasone iontophoresis weekly for at least 3 months at our specialist nail clinic between 1996 and 2011. Response to treatment was assessed on clinical photographs using the nail psoriasis severity index (NAPSI) scoring. In all, 27 patients were assessed, of whom 81 per cent showed an improvement in their nails. The treatment was well tolerated, with only one patient reporting fissuring of the fingertips. Dexamethasone iontophoresis may be a useful treatment of this generally recalcitrant condition.