[Bacterial genome analysis and its applications for infectious diseases].
The availability of genome sequence is revolutionizing the fields of bacteriology and infectious diseases. By the end of 2008, 785 complete genomes including representatives of all notable human pathogens have been sequenced, and over thirty hundreds of bacterial genome projects are going. These huge amount of genomic data has led to unprecedented advances not only in biological interests, but also in pathogen diagnosis, genotyping, detection of virulence, and detection of resistance to antibiotics. In addition, the metagenomic strategy of exploring the complex microbial flora provides a unique access to the understanding of bacterial community interdependence. This genomic information will impact on the research for microbial diseases related on human health.