Aldosterone increases gustatory neural response to NaCl in frog.
1. The effect of aldosterone on frog gustatory response was investigated by recording integrated responses of the whole glossopharyngeal nerve elicited by taste stimuli. 2. After aldosterone (1 microM) was perfused to the basolateral side of taste cells through the lingual artery, the gustatory neural response for a NaCl stimulus was greatly enhanced, but the gustatory responses for CaCl2, hydrochloric acid, quinine hydrochloride and galactose were not affected. 3. At 3 and 6 hr after the onset of aldosterone perfusion, the magnitudes of the responses for NaCl increased to 2.0 and 3.6 times the control, respectively. 4. These results suggest that aldosterone may regulate the gustatory responses for monovalent salts alone.