Overall, annotatr enables a richer biological interpretation of experiments.<br><b>Availability and Implementation</b>: http://bioconductor.org/packages/annotatr/ and https://github.com/rcavalcante/annotatr.<br><b>Contact</b>: rcavalca@umich.edu.<br><b>Supplementary information</b>: Supplementary data are available at Bioinformatics online.<br>