a 54 year old man presented with change in behaviour nocturnal enuresis abnormal limb movement and headache of one week s duration the diagnosis of butterfly glioma glioblastoma multiforme was made based on imaging characteristics and was further confirmed by biopsy findings as the corpus callosum is usually resistant to infiltration by tumours a mass that involves and crosses the corpus callosum is suggestive of an aggressive neoplasm other neoplastic and non neoplastic conditions that may involve the corpus callosum and mimic a butterfly glioma as well as associated imaging features are discussed.