Spleen rates in children: an old and new surveillance tool for malaria elimination initiatives in island settings.
Spleen rates (SR) have been traditionally used to estimate the burden of malaria transmission. Results are presented from 51 surveys, which measured SR and parasite rates (PR) in 29,962 individuals in the archipelago of Vanuatu. Indices for spleen size computed with multivariate statistical tools outperformed the WHO average spleen index and showed that spleen sizes in a population can track shifts in malaria transmission. In general, a positive linear relationship between Plasmodium spp. PR and SR was found for the archipelago. In the context of malaria elimination and for the specific setting of this study we found that spleen examination is a useful tool in post-malaria elimination surveillance. Finally, results highlight the value of measuring spleen sizes to rapidly assess the impact of intervention packages aimed at malaria elimination or control.
This article is the second of two parts. The first one was published in the issue no 2 of this same journal. The preseni study uses the dependency index and the youth ratio to describe the aging process both at regional and municipal levels. Our data show a yet moderate aging process in (he region. with an uneven distribution throughout the different municipalities.