Renal angiography using carbon dioxide.
The many advantages of carbon dioxide (CO2) angiography in the investigation of renal arterial disease include an absence of both nephrotoxicity and allergic reactions. An automated delivery system facilitates injection of CO2 whilst ensuring that there is no contamination of the injection with air. We report our initial experience using a prospective study of this delivery system in 47 patients referred for renal angiography, and assess diagnostic image quality and adverse reactions to CO2 angiography using the automated delivery system. The majority (37/47; 79%) of angiograms were of diagnostic quality and there were no significant adverse reactions in response to the CO2 contrast agent.
Summary Colorectal cancer is currently the third most common cancer in Malaysia. Elevated expression of COX-2, an induced cyclooxygenase isoenzyme, has been seen in colonic adenomas and colorectal carcinoma. There is evidence that inhibition of this COX-2 can decrease the risk of colorectal cancer. Selective COX-2 inhibitors may have a role in reducing the risk of colorectal cancer in high-risk individuals.