Carcinoma of pancreas associated with the 5q-syndrome.
A female patient with the 5q-syndrome (refractory macrocytic anemia with deletion of the long arm of No. 5 chromosome) was followed-up for a period of 33 months and developed a carcinoma of pancreas. Until death she showed no signs of leukemic transformation. This association has not been described, and the genetic predisposition of 5q-patients to malignancies is discussed.
We review some of the recent development in quantum Monte Carlo (QMC) methods for models of strongly correlated electron systems. QMC is a promising general theoretical tool to study many-body systems, and has been widely applied in areas spanning condensed-matter, high-energy, and nuclear physics. Recent progress has included two new methods, the ground-state and finite-temperature constrained path Monte Carlo methods. These methods significantly improve the capability of numerical approaches to lattice models of correlated electron systems. They allow calculations without any decay of the sign, making possible calculations for large system sizes and low temperatures. The methods are approximate. Benchmark calculations show that accurate results on energy and correlation functions can be obtained. This chapter gives a pedagogical introduction to quantum Monte Carlo, with a focus on the constrained path Monte Carlo methods.