Histopathological Picture of Liver of White Rat (Rattus norvegicus) that were Fed Aloe vera Gel after Exposed to Mainstream Kretek Cigarrette Smoke
This study aimed to determine the effect of Aloe vera gel administration on liver hitopathological picture of Rattus norvegicus that are exposed to mainstream kretek cigarette smoke. T
Objective:To investigate the effect of the famesoid X receptor on hepatic lipase expression.Methods:Human hepato- blastoma HepG2 cells were treated with chenodeoxycholic acid and the levels of HL messenger RNA and protein were determined by RT-PCR and Western blotting respectively.Results:HepG2 cells were treated with FXR agonists CDCA with different concentrations of 25μmol/L,50μmol/L,75μmol/L for 6h,12h,24h and 48h,and the levels of HL mRNA and protein were decreased in a dose and time-de- pendent manner.Conclusions:FXR agonist decreases hepatic lipase gene expression.