does fat affect insulin
The current study adds weight to the longstanding recommendation to restrict total fat and saturated fat. While adjusting for BMI eliminates the effect, this does not mean that dietary fat is not important. It is biologically plausible that high-fat diets promote weight gain, which then promotes insulin resistance. There is a large body of evidence that supports this view. In addition, there is growing evidence that obesity plays a central pathogenic role in the development of diabetes (1,2).
Insulin affects several organs and tissues to promote glycogen storage and laying down of fat. Glucose, some amino-acids, and to a much lesser extent fat all promote insulin release. In the liver, insulin increases glucose transport into the liver from the blood, and the synthesis of glycogen.In muscle the effects are similar and in fact the amount of glucose taken up by muscle is a significant contributor to the total glucose disposal rate (GDR). In adipocytes, insulin promotes synthesis of fat.nsulin affects several organs and tissues to promote glycogen storage and laying down of fat. Glucose, some amino-acids, and to a much lesser extent fat all promote insulin release. In the liver, insulin increases glucose transport into the liver from the blood, and the synthesis of glycogen.