Feasibility study of lactate imaging of head and neck tumors.
A proton spectroscopic imaging sequence was used to investigate the feasibility of lactate imaging in head and neck tumors. The sequence employs a two-shot lactate editing method with inversion recovery for additional lipid suppression, and a restricted field of view to suppress motion artifacts. Variations in acquisition parameters and two different receive coils were investigated on twelve patients. Elevated lactate was detected in three patients, no lactate was observed in seven patients, and two studies were inconclusive because of severe motion or inhomogeneity artifacts. Best results were obtained with an anterior/posterior neck coil at a 288 ms echo time (TE).
Abstract The neutralization process of the depolarization field in L-α-alanine doped triglycine sulfate (LATGS) was investigated by the observation of the polarization charge on the surface of LATGS from the moment of cleavage. The charges which were equivalent to such a high voltage as 5kV were actually induced on the surface of the sample at the moment when the sample was cleaved. The charges were neutralized exponentially with time and more slowly in the vacuum cell (≊10Pa) than in atmosphere.