Dynamic Biaxial Tissue Properties of Pregnant Porcine Uterine Tissue
Automobile crashes are the largest cause of death for pregnant females and the leading cause of traumatic fetal injury mortality in the United States. Research for pregnant occupant safety utilizing computational models is limited by available pregnant tissue data. This study collected experimental data from biaxial tissue tests on pregnant uterine tissue at a dynamic rate. Experimental tests were conducted on pregnant porcine uterus which was chosen as a surrogate for the human pregnant uterus. Biaxial dynamic tensile tests were performed. The specimen was loaded at a rate of 0.7 strains per second to match the uterine strain rate in a motor vehicle crash. Experimental results include peak stresses and peak strains for the pregnant uterine tissue in tension. The results can be implemented in pregnant occupant models to evaluate the uterine tissue response to impact loading scenarios.
This review summarizes studies concerning the covalent binding of [14C]TCE to rat liver microsomal protein and exogenous DNA, in vitro, the enhancement of this binding by inducers of mixed-function...