[Thyrotoxicosis due to long-term therapy with interferon alpha in the patient with mixed chronic active hepatitis B and C].
The authors describe a case report of 48-year-old woman treated with Interferon alpha for the chronic active hepatitis B and C. During this therapy thyrotoxicosis occurred. It disappeared after the withdrawal of Interferon alpha and administration of strumigens. Immediately after stopping of the administration of Interferon alpha and three month later antibodies against the thyroid epithelium were found.
Abstract A new kinetic approach is presented to study the mechanism of the catalytic reaction of the hydrogenation of carbon monoxide on Fe–Co–Mn catalyst prepared by wet impregnation method over MgO support. The experimental data obtained by a fixed bed reactor are used for calculating the apparent activity energy of the LHHW kinetic models developed for the consumption of carbon monoxide, and formation of methane, alkenes and alkanes. Then, using the calculated activation energies and the available UBI–QEP relationships for the ternary catalyst and obtaining the relationships between the apparent activity energy of the LHHW kinetic model and the activity energy of surface elementary reactions involved in the kinetic equation extraction and by developing an appropriate software coupled with a genetic optimization algorithm, the surface binding energy of carbon, oxygen and hydrogen on the ternary catalyst are calculated.