Phase 1b/2 study of intratumoral Ad-RTS-hIL-12 + veledimex in patients with chemotherapy-responsive locally advanced or metastatic breast cancer.
TPS3097Background: Immune-based strategies involving T-cell activation have shown significant activity in multiple tumor types. The presence of immune elements in breast cancers has prognostic and ...
Summary Desmoid tumour resection is a known, albeit rare, cause for chest wall reconstruction. Traditionally, musculocutaneous flaps and synthetic mesh materials have been employed for coverage over these potentially large thoracic defects. More recently, biologic mesh materials have become increasingly more prevalent in a multitude of surgical reconstructions. To date, the current literature describes the usage of select biologic materials, such as human cadaveric acellular dermal matrix, in chest wall reconstruction. One variation of the biologic materials, Permacol ® , has not been well described in the literature for chest wall reconstruction. Permacol ® is a porcine lyophilised acellular dermal collagen. We report the successful use of Permacol ® in a complex chest wall reconstruction following the resection of a large desmoid tumour.