Hodgkin's disease presenting in the skin.
Summary ::: ::: Infiltration of the skin in Hodgkin's disease is rare and is usually associated with disseminated disease, with a correspondingly poor prognosis. We present a case of Hodgkin's disease that appeared in the skin with subsequent node involvement. Our patient initially responded well to combination chemotherapy but has subsequently relapsed.
Objective: To study the membrane phospholipid composition of rat hepatoma cells. Method: The mole fraction of phosphatidylcholine (PC) and phosphatidylethanolamine (PE) in total phospholipids of CBRH-7919 hepatoma cells was compared to that of normal liver cells by high performance thin layer chromatography (HPTLC) and phosphorus assay. The composition and mole fraction of fatty acids of PC in hepatoma cells were also compared to those of normal ones with gas chromatographic analysis (GC analysis). Results and Conclusion: The PC content of membrane phospholipids in CBRH-7919 tumor cells, particularly in long chain and unsaturated fatty acids was significantly lower than that of normal cells.