what is park2 gene
PARK2 (OMIM *602544) is the parkin gene that may cause a form of autosomal recessive juvenile Parkinson disease (OMIM 600116) due to a mutation in the parkin protein. This form of genetic mutation may be one of the most common known genetic causes of early-onset Parkinson disease.In one study of patients with onset of Parkinson disease prior to age 40 (10% of all PD patients), 18% had parkin mutations, with 5% homozygous mutations.his form of genetic mutation may be one of the most common known genetic causes of early-onset Parkinson disease. In one study of patients with onset of Parkinson disease prior to age 40 (10% of all PD patients), 18% had parkin mutations, with 5% homozygous mutations.
GeneCards Summary for PKP2 Gene. PKP2 (Plakophilin 2) is a Protein Coding gene. Diseases associated with PKP2 include arrhythmogenic right ventricular dysplasia 9 and arrhythmogenic right ventricular dysplasia/cardiomyopathy 9.his gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families.