Implications for New Trials in Acute Ischemic Stroke in the New Era of Endovascular Therapy
Abstract Although major advances for the treatment of acute ischemic stroke have recently been made through clinical trials, there is still much work to be done and as is common, more and new questions have arisen that will influence how future trials are designed. This chapter will give an overview on the implications of the human ischemia-reperfusion model, discuss advanced neuroimaging as the now established biomarker for stroke and trial eligibility, and review why stroke systems of care have to be considered for future trials.
Budd-Chiari syndrome (BCS) with an intracaval stent is a rare presentation. In most Western patients with BCS, it is predominantly the hepatic veins that are involved, not the inferior vena cava (IVC). In the case presented, the patient had antiphospholipid syndrome with BCS that involved the IVC and required an intracaval stent. Presented with the case study are scanning techniques for BCS and the IVC to help sonographers evaluate the normal and abnormal anatomy and hemodynamics of this system.