is ige elevated in lupus
Anti-IgE IgG autoantibodies have also been observed in SLE patients with lymphoadenopathy, articular involvement and anti-DNA antibodies (9). In addition, increased IgE serum levels were observed in children of mothers with lupus, regardless of the presence of allergic disease in the mothers (34).Another study showed elevated IgE levels in male SLE patients compared with female patients (35).o date, few studies have evaluated the IgE levels in SLE patients (4,6,7). High total IgE serum levels have been associated with disease activity and nephritis in adult SLE patients (4,12-15). However, to our knowledge, no studies have evaluated the association of IgE with juvenile SLE (JSLE).
In between exposures, a person's IgE level may drop. Sometimes an individual has a condition that affects the immune system and will not produce normal amounts of immunoglobulins. In this case, a person could have an allergy that is not reflected by the total IgE test result.