HL-A 27 in reactive arthritis. A study of Yersinia arthritis and Reiter's disease.
The histocompatibility antigen HL-A 27 was identified in 43 of 49 patients with yersinia arthritis and in 36 of 40 patients with Reiter's disease, compared with 3 of 20 patients with yersinia infection without arthritis and 14% of the normal Finnish population. HL-A 2 occurred in patients with reactive arthritis in the same high frequency as did HL-A 27, but this antigen is present in 55% of Finns. HL-A 27 negative patients usually had a mild or somewhat atypical disease.
Abstract Total LDH activity and LDH isoenzyme distribution were determined in sera of in normal children from 4 to 13 years old and compared to a control group of adult sera. It was found that in children the level of total LDH activity and the isoenzyme distribution did not differ significantly from that in adults. When the children were divided into age groups of one year, such differences could not be detected either. No sex-related differences were found. The relativity of the normal LDH isoenzyme distribution pattern is discussed.