Modification of Radiation Effects in Bacteria
Radiobiological studies in bacteria began in 1877 when Downes and Blunt published their observations of the killing of bacteria by sunlight. A voluminous literature has been accumulated since that date, and in a short discussion it is impossible to accomplish more than to mention briefly some aspects of the subject which, hopefully, are of interest.
A healthy tissue tolerance study1,2 with Beagle dogs was carried out at the Finnish BNCT facility FiR 1 during February-March 1998. Three dose groups of dogs without boron carrier, each comprising five Beagles, and one dose group with BPA-F infusion were irradiated. Individual dose plans1 were done for each dog. The absorbed doses, which were actually delivered to healthy tissues, were monitored in vivo by placing the dosimeters on the shaved skin of the dogs or in the accessible cavities. In this study, absorbed gamma doses were monitored with thermoluminescent (TL) dosimeters, and neutron fluences were determined with activation foils. The obtained results were compared to the calculated values.