Gametic equilibrium of four loci on chromosome 1
The present study is the first to investigate gametic disequilibrium of loosely linked loci (recombination greater than 22%) of known map distance in humans. The study population consisted of 302 healthy unrelated individuals of whit mixed-European ancestry living in the Denver, Colorado area. Pair-wise combinations of four loci on chromosome 1 (Rhesus, Duffy, phosphoglucomutase-1, and amylase-2) were examined for nonrandom association of alleles at different loci. Observed and expected values were compared with chi-square goodness-of-fit tests. There was no evidence of first-order interaction, i.e., gametic disequilibrium. From these findings it seems that gametic disequilibrium may not be important in the genetic organization of chromosome 1.
The Learning Style Questionnaire and the Children's Nowicki-Strickland I-E Control Scale were given to 128 boys and girls in Grades 8 and 11 in the La Grande (Oregon) School District. Each subject's previous year's grade point average was obtained to determine the relationships among hemisphericity, locus of control, and achievement. Also assessed, including interactions, were differences in hemisphericity, locus of control, and achievement by sex and grade. There was a significant relationship (of low practical value) between locus of control and GPA only. The difference in hemisphericity scores with respect to grade was significant.