"When you're using gear you put HIV to the back of your mind and forget about it": constructs of risk.
This article presents findings from a qualitative study concerning drug injectors' constructs of human immunodeficiency virus (HIV) risk behavior. Analysis of data obtained from in-depth interviews (some with a vignette) of drug injectors found that when individuals needed an injection of drugs and were experiencing drug withdrawal they were more likely to take drug injecting risks. This was often discussed within an overall preoccupation with drug use. The substantive focus of the analysis goes on to explore drug injectors' desire to think about the consequences of HIV risk behavior at a later point in time. These exploratory findings highlight how further research needs to be undertaken in order to improve understanding of the temporal issues concerning drug injecting HIV risk behavior.
Summary The influence on the blood cholesterol level and on cholesterol biosynthesis ([ 14 C] acetate incorporation) in the liver, small intestine and blood was investigated in rats after daily oral treatment with nicotinic acid, methyltestosterone and an anabolic steroid, PS-179, for one week. Plasma cholesterol levels were significantly decreased with PS-179, but not with nicotinic acid or methyltestosterone. None of the drugs altered the cholesterol levels in the liver and intestine. All drugs produced a significant decrease in the incorporation time of labelled cholesterol into liver and a significant increase in the intestine. Total cholesterol biosynthesis in liver and intestine were not altered with any of these drugs.