what is albumin bound paclitaxel
How Albumin-Bound Paclitaxel Works. Albumin-bound paclitaxel is a chemotherapy drug from the class of taxanes, used as standard treatment of patients with metastatic breast cancer. Chemotherapy can be used alone before a surgery as co-adjuvant therapy, or after the surgery as adjuvant therapy.
Fractional precipitation is a rapid, simple, and efficient procedure for the pre-purification of paclitaxel with high purity and yield. Here, we report optimization of the storage temperature, a key process variable in fractional precipitation, to obtain paclitaxel of high purity and yield in a pre-purification step.n this study, the storage temperature, an important process variable in fractional precipitation, was optimized in terms of the yield and purity of paclitaxel for a fixed methanol concentration in water (61.5%, v/v), paclitaxel content in the crude extract (0.5%, w/v), and storage time (3 days).