Peptide having fibrosis inhibitory activity and composition containing same
The present invention relates to a composition for inhibiting fibrosis and, more specifically, to a composition for inhibiting fibrosis, wherein the composition is effective in inhibiting fibrosis of tissue cells by containing a peptide derived from telomerase. The peptide according to the present invention exhibits an effect of inhibiting the progression of various kinds of fibrosis, including fibrosis due to occurrence of cancer, fibrosis due to the administration of chemotherapy anticancer drugs, fibrosis due to the exposure to radiation, or progressive fibrosis of tissues, including a TGF-β signaling procedure, and thus can provide a composition for anti-fibrosis or inhibiting fibrosis and a method for treating diseases due to fibrosis.
Objective To investigate the relationship between FcγRⅢB gene polymorphisms and susceptibility to chronic periodontitis in Chinese patients. Methods DNA samples with buccal swabs were collected from 63 severe CP patients, 103 initial to moderate CP patients, and 80 healthy controls in Chinese Han nationality. The FcγRⅢB gene polymorphisms were analyzed with PASA. Results There were no significant genotype distribution differences of FcγRⅢB between any two of the three subject groups. Conclusion Further study was needed since we did no find the relationship between the FcγRⅢB gene polymorphism and periodontitis in this present study.