Clinico-immunologic aspects of botulinum toxin type B treatment of cervical dystonia
In this multicenter study of 100 patients with cervical dystonia, we examined the immunogenicity of botulinum toxin type B (BTX-B) and correlated the clinical response with the presence of blocking antibodies (Abs) using a novel mouse protection assay. One-third of the patients who were negative for BTX-B Abs at baseline became positive for BTX-B Abs at last visit. Thus, the high antigenicity of BTX-B limits its long-term efficacy.
INTRODUCTION ::: The aim of this study was to determine whether the new robot hand technique can help to avoid the complication in the course of high precise microneurosurgical operations. ::: ::: ::: METHODS ::: The physical efficacy was measured by tremorometry. The comparative study of the incidence of complications measured the clinical efficacy. ::: ::: ::: RESULTS ::: The tremors of the operating hand and the number of complications have decreased effectively. ::: ::: ::: CONCLUSION ::: The precise level of robots could be available by novel robot hand technique. By this technique the microsurgical work has become more effective.