Study on the Diseases Induced by Glycosylation Mutant Cells
Glycosylation is one of the most common and most important methods to modify cell surfaces.Glycosylation mutants often influence the products' structure and change chemical characteristics of cell surfaces.Regulation of the activity of glycosylation-re- lated enzyme through genetic methods and small chemical molecules will alter glycosylation process and disclose the impact of glycosy- lation products on organism health and the relationship between glycosylation mutants and diseases.
Author contributions ::: ::: GH helped design the study, establish the animal model, collect and analyze samples, and write the manuscript. YY and DH helped establish the animal model, performed Western blotting, immunohistochemistry analyses. YY and DH also helped analyse data and revise the manuscript. QYW and JK contributed to study planning, analyse and interpret data, review and revise the manuscript. All authors have approved the final version of this article to be published and agreed to be accountable for all aspects of the work in ensuring the questions related to the accuracy or integrity of any part of the work. ::: ::: ::: ::: Disclosure ::: ::: The authors report no conflicts of interest in this work.