Discontinuation of anticoagulant therapy for a month in a patient with HeartMate III continuous-flow left ventricular assist device without thromboembolic events
Abstract The recommended anticoagulation regimen for continuous-flow left ventricular assist device (LVAD) systems is warfarin and aspirin with a targeted international normalized ratio (INR) of 2.0–3.0. Our patient is a 58-year-old male who underwent surgical HeartMate III continuous-flow LVAD implantation 3 months ago outside the country. The patient mistakenly stopped taking warfarin for 1 month prior to presenting to our center for a routine visit. Luckily, the patient was doing very well without any complication despite the fact that his INR was 1.0.
This study was performed to examine the acute phase response in calves during dairy calf pneumonia. We measured acute phase proteins (App) and identified some potential markers useful for evaluation of calves’ health status. Sixty Holstein calves were selected in this study. After clinical examination, clinical findings were recorded from physical examination of individual. Two blood samples were taken from the calves. One of the sample had EDTA anti coagulant. Blood samples were used for CBC and serum biochemical analysis. The results of this study showed a significant increase in Hp and fibrinogen. Our results indicated the application of Haptoglobin and fibrinogen measurements as indicators of health in calf herds, thereby facilitating treatment decisions.