Augmentation grafting of the maxillary sinus for placement of dental implants: anatomy, physiology, and procedures.
In patients with an inadequate amount of bone for implant placement, sinus lift surgery can be performed to restore a sufficient amount of alveolar bone to allow for successful implant placement and subsequent prosthetic reconstruction. In this article, the anatomy and physiology of the maxillary sinus, the mechanisms of bone grafting, bone grafting material, preoperative evaluation, surgical technique, and the grafting procedure, as well as intraoperative bleeding and postoperative complications, are discussed.
Background ::: Spontaneously metastatic xenograft models of cancer are infrequent and the few that exist are resource intensive. In xenografts, caliper measurements can be used to determine primary tumor burden and response to therapy but in metastatic disease models determination of the presence of metastatic disease, metastatic burden, and response to therapy are difficult, often requiring serial necropsy. In this study we characterized the development of visceral metastases in a patient derived xenograft model (PDXM) using in vivo imaging.