Neurobiological actions of cysteamine.
Somatostatin (SS)-related peptides act within discrete brain regions to inhibit adrenal epinephrine (E) secretion, to prevent hypothermia, and to produce hyperthermia. Depletion of brain concentrations of these SS-related peptides using cysteamine (CSH) or central administration of an SS receptor antagonist increases adrenal E secretion and impairs thermoregulation. These actions of CSH and the SS receptor antagonist are reversed by administration of SS into the central nervous system. These results support the hypothesis that endogenous brain SS-related peptides are involved in the regulation of adrenal E secretion and thermoregulation.
The Ni-SiC nano-composite coatings were prepared on the ring of stainless steel by using of high frequency pulse electroplating. Orthogonal experiment was used to study optimal dosage of the dispersant. The effect of some factors, such as current density, pH value, temperature , addition agent and so on, were studied. The characterization of Ni-SiC nano-composite coatings were studied by wear test. The effect of pulse frequency and the SiC concentration in the electrolyte on the wear resistance of Ni-SiC nano-composite coatings were studied. The morphology of the nano-composite coatings in wear test before and after were analyzed by SEM and the metaloscope photographs. The results show that Ni-SiC nano-composite coatings of high frequency pulse electroforming have better performance of wear resistance.