Studies on the absorption and disposition of 3H-labelled talc in the rat, mouse, guinea-pig and rabbit
Abstract The absorption and disposition of talc was studied in rats, mice and guinea-pigs, following a single oral dose of 3 H-labelled material. The translocation of talc in the rabbit urogenital tract was studied after single and multiple intravaginal applications. More than 95% of the dose of orally administered talc was excreted in the faeces within 3–4 days by all three species studied. Traces of radioactivity found in the urine probably reflected contamination of the samples by contact with the faeces and the presence of labile 3 H associated with the 3 H-labelled talc. No translocation of talc to the liver or kidneys was found. In the rabbit study, no translocation of talc into the ovaries was detected.
Reference to the AC-13 asphalt mixture gradation,the rubber particles instead of part of the fine aggregate were added to the asphalt mixture as aggregate.Through indoor Marshall test the effect of the rubber particles on the asphalt mixture Marshall mechanical index was analyzed.The results show that by adding the rubber particles the Marshall stability of the asphalt mixture is reduced,and the flow value is increased. Comparing with the large particle size of rubber particles,the use of small particle size rubber particles can improve the Marshall stability,and the flow valus decreases.The Marshall stability of rubber particles asphalt mixture by using petroleum asphalt is lower than that by using SBS modified asphalt.