Effects of Vitamin A on Expressions of Apoptosis Genes Bax and Bcl-2 in Epithelial Cells of Corneal Tissues Induced by Benzalkonium Chloride in Mice with Dry Eye
Background ::: The apoptosis of corneal epithelial cells participates in the pathological processes of dry eye, which is expected to be a treatment target for dry eye. The aim of this study was to investigate the effects of vitamin A (VA) on apoptosis of corneal epithelial cells in a mouse model with dry eye induced by benzalkonium chloride (BAC).
Abstract The intercalation of tris-bipyridyl metal complexes (M(bpy) 3 2+ , M=Ru, Ni, and Co) into the interlayer region of vanadium pentoxide gel (V 2 O 5 ·nH 2 O) was confirmed for the first time. The intercalation of the guest species was conducted by the reaction of the complexes with undried V 2 O 5 gel. The saturated amount of adsorbed M(bpy) 3 2+ was less than the ion exchange capacity of the V 2 O 5 gel because of bulkiness of M(bpy) 3 2+ . The transition temperature to orthorhombic V 2 O 5 was higher than that of original V 2 O 5 gel, indicating the stabilization of the layered structure by the intercalation.