is parkinson's disease autoimmune
The cause of neuronal death in Parkinson's disease is still unknown, but a new study proposes that neurons may be mistaken for foreign invaders and killed by the person's own immune system, similar to the way autoimmune diseases like type I diabetes, celiac disease, and multiple sclerosis attack the body's cells.hese two types of neuronsâone of which is dopamine neurons in a brain region called the substantia nigraâdegenerate during Parkinson's disease. To see if living neurons use MHC-1 to display antigens (and not for some other purpose), Drs.
Parkinson's disease is a common neurodegenerative disorder characterized by the progressive loss of the dopaminergic neurons in the substantia nigra pars compacta.The loss of these neurons is associated with a glial response composed mainly of activated microglial cells and, to a lesser extent, of reactive astrocytes.This glial response may be the source of trophic factors and can protect against reactive oxygen species and glutamate.he role of glial cells in Parkinson's disease. Vila M, Jackson-Lewis V, Guegan GuÃ©gan, C WU, Dc Teismann, P CHOI, Dk Tieu, K Przedborski. s