Eosinophilic granuloma of lymph node: case report with cytohistologic, immunohistochemical, and flow cytometric observations.
A case study of eosinophilic granuloma (Langerhans cell histiocytosis) of lymph node in a 32-year-old white man is presented. Clinical, cytologic, histologic, immunohistochemical, and flow cytometric findings are reported. Intraoperative cytologic findings can serve as valuable adjuncts to the frozen section, in this case serving as the sole method for diagnosis. This case is presented in light of the rarity of node-based eosinophilic granuloma and the absence of flow cytometric immunophenotypic findings in the literature.
Upstream Electromigration (EM) study was performed on different multiple via structures with different Cu line dimensions. EM performance was found to be dependent on both via layout and Cu line dimension. Failure analysis showed different EM failure modes and diffusion paths on these structures with their different grain morphology. Finite element analysis is applied to find out the current density profiles of these structures and explain their EM results. Simulated resistance increase was found to be dependent on the size and location of EM induced void in these structures.