Cocaine, cadherins and synaptic plasticity
Addictive substances hijack the reward system partly via synaptic plasticity onto dopamine neurons. Cadherins may contribute to cocaine-evoked adaptations, supporting the notion that drug addiction is a synaptic disease.
Purpose ::: This study focuses on nanoscale self–assembly peptides (SAP) modified demineralized bone matrix (DBM) which provided a more effective osteogenesis and regeneration for critically-sized femur defects in goats using the selective cell retention (SCR) strategy.