Use of methotrexate for psoriasis in Wales
We present the results of a survey which looked at the use of methotrexate for psoriasis by the 15 consultant dermatologists practising in Wales. A total of 127 patients were seen over the 3 months studied. There was a need for improvement in record keeping, in particular recording the indication for methotrexate, what information was given to the patient and the patient's alcohol consumption. We found a wide variation in the practice of routine liver biopsy in patients on long-term methotrexate. In 42% of the patients a liver biopsy was appropriate, but had not been performed. As a result of this study a set of ‘aims for audit purposes’ has been proposed for use in future audit studies.
Phyllodes tumour is a rare biphasic fibroepithelial neoplasm that comprises <1% of all neoplasms of breast.1 Metaplastic changes in a phyllodes tumour, though reported, is an infrequently occurring event. Here we present a case of a 30 year old female who presented with a breast lump. Histopathological examination revealed a benign phyllodes tumour with florid squamous metaplasia. This case is presented for its rarity.