[Vascular prostheses complications in autopsy material].
The early and late complications of vascular grafts in the Department of Vascular Surgery of Semmelweis University Medical School are discussed on the basis of a five year post mortem material. The mortality of the operations was 11.5%. Haemorrhage and infection are considered the most serious complications. The cause of the complications are discussed.
Background ::: Spontaneously metastatic xenograft models of cancer are infrequent and the few that exist are resource intensive. In xenografts, caliper measurements can be used to determine primary tumor burden and response to therapy but in metastatic disease models determination of the presence of metastatic disease, metastatic burden, and response to therapy are difficult, often requiring serial necropsy. In this study we characterized the development of visceral metastases in a patient derived xenograft model (PDXM) using in vivo imaging.