A review of the role of glial cells in understanding retinal disease.
Retinal vascular diseases such as diabetic retinopathy and retinopathy of prematurity are major causes of visual loss. Although the focus of a great deal of research has been on the aetiology of vascular growth, it is now emerging that anomalies in other retinal cell types, especially glial cells, occur very early in the course of the disease. Glial cells have major roles in every stage of disease, from the earliest subtle variations in neural function, to the development of epi-retinal membranes and tractional detachment. Therefore, having a firm understanding of the function of retinal glia is important in our understanding of retinal disease and is crucial for the development of new treatment strategies.
The purpose of the model presented by Glance et al is to study the ‘contribute vs. free-ride’ dilemma present in organizations. This social dilemma is present on two intertwined levels, the managerial front and the base level of workers. This model also seeks to define a correlation (if one does exist) between worker turnover and productivity rates.