Nicotinic acid analogs: effects on response of chick embryos and hens to organophosphate toxicants.
Embryonic abnormalities are known to be induced in chick embryos when they are injected with certain organophosphate insecticides prior to incubation. The marked teratogenic effects of Bidrin [3-(dimethoxyphosphinyloxy) N, N-dimethyl-cis-crotonamide] can be alleviated by many analogs of nicotinamide and nicotinamide adenine dinucleotide. Successive hydroxylation and N-dealkylation of Bidrin in the egg are not greatly altered by injection of nicotinamide. The delayed neurotoxicity in adult hens after administering tri-o-cresyl phosphate is also partially relieved by administering certain nicotinamide analogs.
The Ni-SiC nano-composite coatings were prepared on the ring of stainless steel by using of high frequency pulse electroplating. Orthogonal experiment was used to study optimal dosage of the dispersant. The effect of some factors, such as current density, pH value, temperature , addition agent and so on, were studied. The characterization of Ni-SiC nano-composite coatings were studied by wear test. The effect of pulse frequency and the SiC concentration in the electrolyte on the wear resistance of Ni-SiC nano-composite coatings were studied. The morphology of the nano-composite coatings in wear test before and after were analyzed by SEM and the metaloscope photographs. The results show that Ni-SiC nano-composite coatings of high frequency pulse electroforming have better performance of wear resistance.