Serial CA 125 levels during chemotherapy for metastatic or recurrent endometrial cancer.
The purpose of this study was to evaluate the role of serial CA 125 in monitoring disease status during chemotherapy in women with metastatic or recurrent endometrial cancer. CA 125 was measured in 21 women receiving cisplatin, etoposide, and Adriamycin for a total of 275 courses of chemotherapy (median eight). Eight of ten patients had elevated pre-therapy CA 125 levels (median 233 U/mL). CA 125 became and/or remained negative in all 20 women with responding or stable disease and was elevated in all nine patients who relapsed. The median level at the time of relapse was 56 U/mL. Levels were elevated before clinical relapse in five of nine patients (56%). Serial CA 125 may aid in the management of women receiving chemotherapy for advanced or recurrent endometrial cancer.
Corrosion and protection of the underwater steel structures for W114A platform were investigated.The offshore platform has been in service in the South China Sea for 15 years.It was found that the bio-fouling was serious and the maximum attachment thickness was 20cm,while,the cathodic protection system was normal and the protective effect was favorable.After analyzing the detective methods and their results,some problems were found.The program of potential detection was inappropriate,the detection method for physical size of the sacrificial anodes was inaccurate,and the base surface of the thickness measurement points was not clean;therefore,the cathodic protective effect could not be accuraely evaluated.To solve these problems,some valuable suggestions are put forward accordingly.