Method and device for metering medicaments
The medicament, preferably there is disclosed a method and apparatus for metering a liquid. In order to achieve an improved metering accuracy, produced by batch-wise first component, for example second part of the molding chamber matching group, for example, it is combined with a transfer tube, wherein the matching group, the optimum seal between the components to be achieved, the selection as a function of at least one decisive significant magnitude of the respective batch and is characterized by the essential magnitude of the second component. Molding chamber, recess, groove, a guide tube, a shoulder
Background ::: Spontaneously metastatic xenograft models of cancer are infrequent and the few that exist are resource intensive. In xenografts, caliper measurements can be used to determine primary tumor burden and response to therapy but in metastatic disease models determination of the presence of metastatic disease, metastatic burden, and response to therapy are difficult, often requiring serial necropsy. In this study we characterized the development of visceral metastases in a patient derived xenograft model (PDXM) using in vivo imaging.