Biphasic responses to acetylcholine in mammalian reticulospinal neurons
Acetylcholine (ACh) responses were elicited by ionophoresis from neurons, located in the medial pontine reticular formation, which were antidromically identified as having axons projecting in the reticulospinal tracts. Most neurons were silent at rest and could be caused to discharge at a regular, slow rate by a constant application of glutamate. ACh altered this slow rate of firing in 28 of 29 cells but showed three different patterns of effect: approximately one-third were excited, one-third were inhibited, and one-third showed biphasic inhibition-excitation. The ACh responses were not sensitive to atropine. These observations suggest that reticulospinal neurons have ACh receptors mediating both inhibition and excitation, perhaps located on different portions of the same neuron.
Abstract A very promising spin physics programme will be soon on the way at the BNL Relativistic Heavy Ion Collider (RHIC). By studying the spin asymmetries for various processes (single photon, single jet and W ± production), we will compare the different predictions obtained using some sets of polarized parton distributions, available in the recent literature. We will put some emphasise on the analysis of the anticipated errors, given the event rates expected from this high luminosity new machine and the current acceptance for the detector systems at RHIC.