Since all these are changes in how we live, not anything innate, we have to conclude that what we are describing here are effects of environment, not genes.
Given that this are changes in lifestyle, we should conclude that we are talking about environmental effects.
From Harajuku Station on the Japan Railways Yamanote loop line, it's but a few steps to Meiji Jingu, the shrine dedicated to the spirits of the Emperor Meiji (who died in 1912) and the Empress Shoken.