While on a second expedition to colonize Florida, in 1521, Ponce de Leen was critically wounded during an attack by Indians; the explorer hoped to return Puerto Rico but lost his fight for life on the way back, in Havana, Cuba.
Ponce de Leen was injured in an expedition.
Bias detection methods may be inadequate; may fail to take into account diverse views about program goals and purposes; competence of all on-site observers may not be sufficiently high; can be costly due to study size; the demands of data management, data quality control, validation procedures, and analytic model (within site, cross site, etc.) may lead to cutting too many corners to maintain quality