APL
APL is an abbreviation, acronym, or initialism that may refer to:

Science and technology 
132524 APL, an asteroid
Abductor pollicis longus muscle, in the human hand
Acute promyelocytic leukemia, a subtype of acute myelogenous leukemia
Applied Physics Letters, a physics journal
Nampula Airport (IATA airport code: APL), in Mozambique

Computers
 .apl, the file extension of the Monkey's Audio metadata file
 AMD Performance Library, renamed Framewave, a computer compiler library
 APL (programming language), an array-based programming language
 APL (codepage), the character set for programming in APL
 Address Prefix List, a DNS record type
 Address programming language, an early high-level programming language developed in the Soviet Union
 Advanced Physical Layer, an extension of Ethernet 10BASE-T1L for field devices
 Alexa Presentation Language, a language for developing Amazon Alexa skills

Software licences
 Adaptive Public License, an Open Source license from the University of Victoria, Canada
 AROS Public License, a license of AROS Research Operating System
 Arphic Public License, a free font license

Organizations
APL (shipping company), a Singapore-based container and shipping company
Aden Protectorate Levies, a militia force for local defense of the Aden Protectorate
Advanced Production and Loading, a Norwegian marine engineering company formed in 1993
Afghanistan Premier League, an Afghan Twenty20 cricket league
Afghan Premier League, a men's football league in Afghanistan 
American Patriot League, a proposed American football spring league
American Premiere League, a Twenty20 cricket league in the US
American President Lines, a container transportation and shipping company
American Protective League, a World War I-era pro-war organization
Applied Physics Laboratory, at Johns Hopkins University
Applied Physics Laboratory at the University of Washington
Association of Pension Lawyers, UK
Aurora Public Library (disambiguation)
Australian Professional Leagues, an Australian soccer governing body
Irish Anti-Partition League, a Northern Ireland political organisation

Other uses
apl.de.ap (born 1974), pseudonym of Allan Pineda Lindo, Filipino-American musician
 Auxiliary Personal Living, a US Navy hull classification for barracks craft; see