Although the monoaminergic neurotransmitters serotonin (5-HT), noradrenaline (NA) and dopamine (DA) are proven to be related to the occurrence of depressive disorders, it is now recognized that monoamine deficits are not sufficient to explain the mechanism of action of antidepressant medications.
ເຖິງແມ່ນວ່າ neurotransmitters neurotransmitter serotonin (5-HT), noradrenaline (NA) ແລະ dopamine (DA) ໄດ້ຖືກພິສູດວ່າກ່ຽວຂ້ອງກັບການປະກົດຕົວຂອງຄວາມຜິດປົກກະຕິຊຶມເສົ້າໄດ້, ມັນໄດ້ຮັບການຍອມຮັບວ່າການຂາດດຸນ monoamine ແມ່ນບໍ່ພຽງພໍທີ່ຈະອະທິບາຍກົນໄກຂອງການປະຕິບັດຂອງ antidepressant ຢາປິ່ນປົວ.