The 26S proteasome degrades various proteins critical to cancer cell survival, such as cyclins, tumor suppressors, BCL-2, and cyclin-dependent kinase inhibitors.
ການປົກປ້ອງ 26S degrades ໂປຼຕີນຕ່າງໆທີ່ສໍາຄັນຕໍ່ການຢູ່ລອດຂອງເຊນມະເຮັງເຊັ່ນ: cyclins, suppressors tumor, BCL-2, ແລະຢາຕ້ານເຊື້ອ kinase ທີ່ຂື້ນກັບ cyclin.