Caffeic Acid Phenethyl Ester powder (CAPE powder) is the active component of propolis, a honeybee hive product. Caffeic Acid Phenethyl Ester powder is a specific inhibitor of the nuclear transcription factor, NF-κB. CAPE powder has been shown to significantly suppress the lipoxygenase pathway of arachidonic acid metabolism during inflammation. Caffeic Acid Phenethyl Ester powder inhibits HIV-1 integrase, and also inhibits proliferation of transformed cells. It induces apoptosis in transformed fibroblasts, and interferes with EGF signal transduction affecting both protein kinase C and ornithine decarboxylase activity.
ຝຸ່ນ Caffeic Acid Phenethyl Ester powder (CAPE powder) ເປັນສ່ວນປະກອບຂອງ propolis, ເປັນຜະລິດຕະພັນຮັງເຜິ້ງ. ຝຸ່ນ Phenethyl Ester ກົດ Caffeic Acid ເປັນຕົວຍັບຍັ້ງສະເພາະຂອງປັດໄຈການສໍາຫຼວດ nuclear, NF-κB. ຜົງ CAPE ໄດ້ຖືກສະແດງໃຫ້ເຫັນເຖິງຄວາມກົດດັນຕໍ່ເສັ້ນທາງ lipoxygenase ຂອງການຍ່ອຍອາຫານຂອງອາຊາກໂດນີຊີໃນໄລຍະການອັກເສບ. ຝຸ່ນ Phenethyl Ester ກົດ Caffeic inhibits HIV-1 integrase, ແລະຍັງ inhibits ການຂະຫຍາຍຕົວຂອງຈຸລັງທີ່ໄດ້ຮັບການປ່ຽນແປງ. ມັນເຮັດໃຫ້ apoptosis ໃນ fibroblasts ຫັນ, ແລະຂັດຂວາງການ transduction ສັນຍານ EGF ທີ່ມີຜົນກະທົບທັງການເຄື່ອນໄຫວຂອງໂປຕີນ kinase C ແລະ ornithine decarboxylase.