While THC is a partial agonist for CB-1 receptors, it is usually mediated by other cannabinoids and terpenes in the plant, and when those were taken away negative effects were realized.
ໃນຂະນະທີ່ THC ແມ່ນ agonist ບາງສ່ວນ ສໍາ ລັບ receptors CB-1, ມັນມັກຈະຖືກໄກ່ເກ່ຍໂດຍ cannabinoids ແລະ terpenes ອື່ນໆໃນຕົ້ນໄມ້, ແລະໃນເວລາທີ່ສິ່ງເຫລົ່ານັ້ນຖືກເອົາໄປສົ່ງຜົນກະທົບທາງລົບໄດ້ຖືກຮັບຮູ້.