Make the text more understandable: +List of p-values used at each interim analysis, assuming the overall p-value for the trial is 0.05 Number ofplanned analyses Interim analysis p-value threshold 2 1 0.001 2 (final) 0.05 3 1 0.001 2 0.001 3 (final) 0.05 4 1 0.001 2 0.001 3 0.001 4 (final) 0.05 5 1 0.001 2 0.001 3 0.001 4 0.001 5 (final) 0.05
+List of p-values used at each interim analysis, assuming the overall p-value for the trial is 0.05 Number ofplanned analyses Interim analysis p-value threshold 2 1 0.0001 2 (final) 0.05 3 1 0.001 2 0.001 3 (final) 0.05 4 1 0.001 2 0.001 3 0.001 4 (final) 0.05 5 1 0.001 2 0.001 3 0.001 4 0.001 5 (final) 0.05