1. A method, comprising: retrieving stored analyte sensor data; receiving analyte sensor data from an analyte sensor; receiving reference measurement values associated with an analyte level; determining sensitivity values based on the retrieved stored analyte sensor data, the received analyte sensor data and the reference measurement values; determining a sensitivity parameter of the analyte sensor based on the determined sensitivity values; and performing a probability analysis of the determined sensitivity parameter to determine a presence of a signal attenuation condition of the analyte sensor.